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Eine Ebene höherGruppiert nach: Dokumententyp |
Veröffentlichungsdatum
Anzahl der Publikationen: 29
2024
Germer, Janin; Lessl, Anna-Lina; Pöhmerer, Jana; Grau, Melina; Weidinger, Eric; Höhn, Miriam; Yazdi, Mina; Cappelluti, Martino Alfredo; Lombardo, Angelo; Lächelt, Ulrich und Wagner, Ernst 
ORCID: https://orcid.org/0000-0001-8413-0934
(2024):
Lipo-Xenopeptide Polyplexes for CRISPR/Cas9 based Gene editing at ultra-low dose.
In: Journal of Controlled Release, Bd. 370: S. 239-255
[PDF, 10MB]
ORCID: https://orcid.org/0000-0001-8413-0934
(2024):
Lipo-Xenopeptide Polyplexes for CRISPR/Cas9 based Gene editing at ultra-low dose.
In: Journal of Controlled Release, Bd. 370: S. 239-255
[PDF, 10MB]
2022
Lin, Yi; Wilk, Ulrich; Poehmerer, Jana; Hörterer, Elisa; Höhn, Miriam; Luo, Xianjin; Mai, Hongcheng; Wagner, Ernst und Lächelt, Ulrich
(2022):
Folate Receptor-Mediated Delivery of Cas9 RNP for Enhanced Immune Checkpoint Disruption in Cancer Cells.
In: Small, Bd. 19, Nr. 2, 2205318
Lyu, Meng; Yazdi, Mina; Lin, Yi; Höhn, Miriam; Lächelt, Ulrich und Wagner, Ernst
(2022):
Receptor-Targeted Dual pH-Triggered Intracellular Protein Transfer.
In: ACS Biomaterials Science & Engineering, Bd. 10, Nr. 1: S. 99-114
Lin, Yi; Wagner, Ernst und Lächelt, Ulrich
(2022):
Non-viral delivery of the CRISPR/Cas system: DNA versus RNA versus RNP.
In: Biomaterials Science, Bd. 10, Nr. 5: S. 1166-1192
2021
Loy, Dominik M.; Krzyszton, Rafal; Lächelt, Ulrich; Rädler, Joachim O. und Wagner, Ernst
(2021):
Controlling Nanoparticle Formulation: A Low-Budget Prototype for the Automation of a Microfluidic Platform.
In: Processes, Bd. 9, Nr. 1, 129
Krhač Levačić, Ana; Berger, Simone; Mueller, Judith; Wegner, Andrea; Lächelt, Ulrich; Dohmen, Christian; Rudolph, Carsten und Wagner, Ernst
(2021):
Dynamic mRNA polyplexes benefit from bioreducible cleavage sites for in vitro and in vivo transfer.
In: Journal of Controlled Release, Bd. 339: S. 27-40
Kamenac, Andrej; Schilberth, Felix L.; Wagner, Ernst; Wixforth, Achim; Lächelt, Ulrich und Westerhausen, Christoph
(2021):
Transient Permeabilization of Living Cells: Combining Shear Flow and Acoustofluidic Trapping for the Facilitated Uptake of Molecules.
In: Processes, Bd. 9, Nr. 6, 913
2019
Kuhn, Jasmin; Klein, Philipp M.; Danaf, Nader al; Nordin, Joel Z.; Reinhard, Sören; Loy, Dominik M.; Höhn, Miriam; Andaloussi, Samir el; Lamb, Don C.; Wagner, Ernst; Aoki, Yoshitsugu; Lehto, Taavi und Lächelt, Ulrich
(2019):
Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles.
In: Advanced Functional Materials, Bd. 29, Nr. 48, 1906432
[PDF, 1MB]
Steinborn, Benjamin; Hirschle, Patrick; Höhn, Miriam; Bauer, Tobias; Barz, Matthias; Wuttke, Stefan; Wagner, Ernst und Lächelt, Ulrich
(2019):
Core‐Shell Functionalized Zirconium‐Pemetrexed Coordination Nanoparticles as Carriers with a High Drug Content.
In: Advanced Therapeutics, Bd. 2, Nr. 11
[PDF, 7MB]
2017
Levacic, Ana Krhac; Morys, Stephan; Kempter, Susanne; Lächelt, Ulrich und Wagner, Ernst
(2017):
Minicircle Versus Plasmid DNA Delivery by Receptor-Targeted Polyplexes.
In: Human Gene therapy, Bd. 28, Nr. 10: S. 862-874
Röder, Ruth; Preiß, Tobias; Hirschle, Patrick; Steinborn, Benjamin; Zimpel, Andreas; Höhn, Miriam; Rädler, Joachim O.; Bein, Thomas; Wagner, Ernst; Wuttke, Stefan und Lächelt, Ulrich
(2017):
Multifunctional Nanoparticles by Coordinative Self-Assembly of His Tagged Units with Metal Organic Frameworks.
In: Journal of the American Chemical Society, Bd. 139, Nr. 6: S. 2359-2368
Wang, Shanshan; Reinhard, Sören; Li, Chengyi; Qian, Min; Jiang, Huiling; Du, Yilin; Lächelt, Ulrich; Lu, Weiyue; Wagner, Ernst und Huang, Rongqin
(2017):
Antitumoral Cascade-Targeting Ligand for IL-6 Receptor-Mediated Gene Delivery to Glioma.
In: Molecular therapy, Bd. 25, Nr. 7: S. 1556-1566
Zhang, Peng; Steinborn, Benjamin; Lächelt, Ulrich; Zahler, Stefan und Wagner, Ernst
(2017):
Lipo-Oligomer Nanoformulations for Targeted Intracellular Protein Delivery.
In: Biomacromolecules, Bd. 18, Nr. 8: S. 2509-2520
Liu, Xiaowen; Zhang, Peng; Rodl, Wolfgang; Maier, Kevin; Lächelt, Ulrich und Wagner, Ernst
(2017):
Toward Artificial Immunotoxins: Traceless Reversible Conjugation of RNase A with Receptor Targeting and Endosomal Escape Domains.
In: Molecular Pharmaceutics, Bd. 14, Nr. 5: S. 1439-1449
Wang, Shanshan; Li, Chengyi; Qian, Min; Jiang, Huiling; Shi, Wei; Chen, Jian; Lächelt, Ulrich; Wagner, Ernst; Lu, Weiyue; Wang, Yi und Huang, Rongqin
(2017):
Augmented glioma-targeted theranostics using multifunctional polymer-coated carbon nanodots.
In: Biomaterials, Bd. 141: S. 29-39
Trübenbach, Ines; Gorges, Jan; Kuhn, Jasmin; Kern, Sarah; Baratti, Emanuele; Kazmaier, Uli; Wagner, Ernst und Lächelt, Ulrich
(2017):
Sequence-Defined Oligoamide Drug Conjugates of Pretubulysin and Methotrexate for Folate Receptor Targeted Cancer Therapy.
In: Macromolecular Bioscience, Bd. 17, Nr. 10, 1600520
Hall, Arnaldur; Lächelt, Ulrich; Bartek, Jiri; Wagner, Ernst und Moghimi, Seyed Moein
(2017):
Polyplex Evolution: Understanding Biology, Optimizing Performance.
In: Molecular therapy, Bd. 25, Nr. 7: S. 1476-1490
Heller, Philipp; Hobernik, Dominika; Lächelt, Ulrich; Schinnerer, Meike; Weber, Benjamin; Schmidt, Manfred; Wagner, Ernst; Bros, Matthias und Barz, Matthias
(2017):
Combining reactive triblock copolymers with functional cross-linkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines.
In: Journal of Controlled Release, Bd. 258: S. 146-160
Morys, Stephan; Levacic, Ana Krhac; Urnauer, Sarah; Kempter, Susanne; Kern, Sarah; Rädler, Joachim O.; Spitzweg, Christine; Lächelt, Ulrich und Wagner, Ernst
(2017):
Influence of Defined Hydrophilic Blocks within Oligoaminoamide Copolymers: Compaction versus Shielding of pDNA Nanoparticles.
In: Polymers, Bd. 9, Nr. 4, 142
[PDF, 2MB]
2016
Lächelt, Ulrich; Levacic, Ana Krhac; Wendel, Dominik und Wagner, Ernst
(2016):
Nonviral Gene Transfer by Sequence-Defined Proton-Sponges with Combined Nucleic Acid Binding and Endosomal Buffering: Balancing Basicities.
In: Molecular therapy, Bd. 24:
S195-S195
Lee, Dian-Jang; He, Dongsheng; Kessel, Eva; Padari, Kärt; Kempter, Susanne; Lächelt, Ulrich; Rädler, Joachim O.; Pooga, Margus und Wagner, Ernst
(2016):
Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes.
In: Journal of Controlled Release, Bd. 244: S. 280-291
Lee, Dian-Jang; Kessel, Eva; Edinger, Daniel; He, Dongsheng; Klein, Philipp M.; Voith von Voithenberg, Lena; Lamb, Don C.; Lächelt, Ulrich; Lehto, Taavi und Wagner, Ernst
(2016):
Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand.
In: Biomaterials, Bd. 77: S. 98-110
Zimpel, Andreas; Preiß, Tobias; Röder, Ruth; Engelke, Hanna; Ingrisch, Michael; Peller, Michael; Rädler, Joachim O.; Wagner, Ernst; Bein, Thomas; Lächelt, Ulrich und Wuttke, Stefan
(2016):
Imparting Functionality to MOF Nanoparticles by External Surface Selective Covalent Attachment of Polymers.
In: Chemistry of Materials, Bd. 28, Nr. 10: S. 3318-3326
Liu, Xiaowen; Zhang, Peng; He, Dongsheng; Rödl, Wolfgang; Preiß, Tobias; Rädler, Joachim O.; Wagner, Ernst und Lächelt, Ulrich
(2016):
pH-Reversible Cationic RNase A Conjugates for Enhanced Cellular Delivery and Tumor Cell Killing.
In: Biomacromolecules, Bd. 17, Nr. 1: S. 173-182
He, Dongsheng; Müller, Katharina; Levacic, Ana Krhac; Kos, Petra; Lächelt, Ulrich und Wagner, Ernst
(2016):
Combinatorial Optimization of Sequence-Defined Oligo(ethanamino)amides for Folate Receptor-Targeted pDNA and siRNA Delivery.
In: Bioconjugate Chemistry, Bd. 27, Nr. 3: S. 647-659
Westerhausen, Christoph; Schnitzler, Lukas G.; Wendel, Dominik; Krzyszton, Rafal; Lächelt, Ulrich; Wagner, Ernst; Rädler, Joachim O. und Wixforth, Achim
(2016):
Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles.
In: Micromachines, Bd. 7, Nr. 9, 150
[PDF, 4MB]
2014
Kos, Petra; Lächelt, Ulrich; Herrmann, Annika; Mickler, Frauke M.; Krhač Levačić, Ana; Morys, Stephan; Bräuchle, Christoph und Wagner, Ernst
(2014):
Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer.
In: Nanoscale, Bd. 7, Nr. 12: S. 5350-5362
[PDF, 0B]
2012
Dohmen, Christian; Edinger, Daniel; Fröhlich, Thomas; Schreiner, Laura; Lächelt, Ulrich; Troiber, Christina; Rädler, Joachim O.; Hadwiger, Philipp; Vornlocher, Hans-Peter und Wagner, Ernst
(2012):
Nanosized Multifunctional Polyplexes for Receptor-Mediated SiRNA Delivery.
In: ACS Nano, Bd. 6, Nr. 6: S. 5198-5208
[PDF, 660kB]
Martin, Irene; Dohmen, Christian; Mas-Moruno, Carlos; Troiber, Christina; Kos, Petra; Schaffert, David; Lächelt, Ulrich; Teixido, Meritxell; Günther, Michael; Kessler, Horst; Giralt, Ernest und Wagner, Ernst
(2012):
Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery.
In: Organic and Biomolecular Chemistry, Bd. 10, Nr. 16: S. 3258-3268
[PDF, 1MB]