Anzahl der Publikationen: 247
Zeitschriftenartikel
Vos, Winnie G.; van Os, Bram W.; den Toom, Myrthe; Beckers, Linda; van Roomen, Cindy P. A. A.; van Tiel, Claudia M.; Mohapatra, Bhopal C.; Band, Hamid; Nitz, Katrin; Weber, Christian; Atzler, Dorothee; de Winther, Menno P. J.; Bosmans, Laura A.; Lutgens, Esther und Seijkens, Tom T. P.
(2024):
T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation.
In: Frontiers in Immunology, Bd. 15, 1297893
[PDF, 3MB]
Doering, Yvonne; van der Vorst, Emiel P. C.; Yan, Yi; Neideck, Carlos; Blanchet, Xavier; Jansen, Yvonne; Kemmerich, Manuela; Bayasgalan, Soyolmaa; Peters, Linsey J. F.; Hristov, Michael; Bidzhekov, Kiril; Yin, Changjun; Zhang, Xi; Leberzammer, Julian; Li, Ya; Park, Inhye; Kral, Maria; Nitz, Katrin; Parma, Laura; Gencer, Selin; Habenicht, Andreas J. R.; Faussner, Alexander; Teupser, Daniel; Monaco, Claudia; Holdt, Lesca; Megens, Remco T. A.; Atzler, Dorothee; Santovito, Donato; von Hundelshausen, Philipp und Weber, Christian
(2024):
Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive atherosclerosis.
In: Nature Cardiovascular Research, Bd. 3, Nr. 2
[PDF, 21MB]
Strohm, Lea; Daiber, Andreas; Ubbens, Henning; Krishnankutty, Roopesh; Oelze, Matthias; Kuntic, Marin; Hahad, Omar; Klein, Veronique; Hoefer, Imo E.; von Kriegsheim, Alex; Kleinert, Hartmut; Atzler, Dorothee; Lurz, Philipp; Weber, Christian; Wild, Philipp S.; Muenzel, Thomas; Knosalla, Christoph; Lutgens, Esther und Daub, Steffen
(2024):
Role of inflammatory signaling pathways involving the CD40-CD40L-TRAF cascade in diabetes and hypertension-insights from animal and human studies.
In: Basic Research in Cardiology
[PDF, 2MB]
Wang, Yong; Li, Guo; Chen, Bingni; Shakir, George; Volz, Mario; van der Vorst, Emiel P C ORCID: https://orcid.org/0000-0001-5771-6278; Maas, Sanne L.; Geiger, Martina; Jethwa, Carolin; Bartelt, Alexander ORCID: https://orcid.org/0000-0001-7840-3991; Li, Zhaolong; Wettich, Justus; Sachs, Nadja; Maegdefessel, Lars; Nazari Jahantigt, Maliheh; Hristov, Michael; Lacy, Michael; Lutz, Beat ORCID: https://orcid.org/0000-0002-1062-6889; Weber, Christian ORCID: https://orcid.org/0000-0003-4610-8714; Herzig, Stephan; Guillamat Prats, Raquel und Steffens, Sabine ORCID: https://orcid.org/0000-0002-6892-9751
(2024):
Myeloid cannabinoid CB1 receptor deletion confers atheroprotection in male mice by reducing macrophage proliferation in a sex-dependent manner.
In: Cardiovascular Research, Bd. 120, Nr. 12: S. 1411-1426
[PDF, 2MB]
Santovito, Donato ORCID: https://orcid.org/0000-0003-1811-4746; Henderson, James M. ORCID: https://orcid.org/0000-0002-6767-6545; Bidzhekov, Kiril; Triantafyllidou, Vasiliki; Jansen, Yvonne; Chen, Zhifen ORCID: https://orcid.org/0000-0002-1622-2105; Farina, Floriana M. ORCID: https://orcid.org/0000-0002-5105-5672; Diagel, Anastasiia; Aslani, Maria; Blanchet, Xavier ORCID: https://orcid.org/0000-0001-7936-3848; Schunkert, Heribert ORCID: https://orcid.org/0000-0001-6428-3001; Megens, Remco T.A. ORCID: https://orcid.org/0000-0001-9871-6696; Döring, Yvonne ORCID: https://orcid.org/0000-0001-9307-3396; Sattler, Michael ORCID: https://orcid.org/0000-0002-1594-0527 und Weber, Christian ORCID: https://orcid.org/0000-0003-4610-8714
(2024):
Mex3a Protects Against Atherosclerosis. Evidence From Mice and Humans.
In: Circulation, Bd. 150, Nr. 15: S. 1213-1216
Krammer, Christine; Yang, Bishan; Reichl, Sabrina; Besson‐Girard, Simon ORCID: https://orcid.org/0000-0003-1194-5256; Ji, Hao; Bolini, Verena; Schulte, Corinna; Noels, Heidi; Schlepckow, Kai; Jocher, Georg; Werner, Georg; Willem, Michael; El Bounkari, Omar ORCID: https://orcid.org/0000-0002-3051-2096; Kapurniotu, Aphrodite ORCID: https://orcid.org/0000-0001-6124-7232; Gokce, Ozgun; Weber, Christian; Mohanta, Sarajo ORCID: https://orcid.org/0000-0001-6144-4092 und Bernhagen, Jürgen ORCID: https://orcid.org/0000-0003-2996-2652
(2023):
Pathways linking aging and atheroprotection in Mif‐deficient atherosclerotic mice.
In: The FASEB Journal, Bd. 37, Nr. 3
[PDF, 12MB]
Mohanta, Sarajo K.; Sun, Ting; Lu, Shu; Wang, Zhihua; Zhang, Xi; Yin, Changjun; Weber, Christian und Habenicht, Andreas J. R.
(2023):
The Impact of the Nervous System on Arteries and the Heart: The Neuroimmune Cardiovascular Circuit Hypothesis.
In: Cells, Bd. 12, Nr. 20, 2485
[PDF, 1MB]
Ebert, Simon; Zang, Lan; Ismail, Noor; Otabil, Michael; Frohlich, Adrian; Egea, Virginia; Acs, Susann; Hoeberg, Mikkel; Berres, Marie-Luise; Weber, Christian; Moreira, Jose M. A.; Ries, Christian; Bernhagen, Juergen und El Bounkari, Omar
(2023):
Tissue Inhibitor of Metalloproteinases-1 Interacts with CD74 to Promote AKT Signaling, Monocyte Recruitment Responses, and Vascular Smooth Muscle Cell Proliferation.
In: Cells, Bd. 12, Nr. 14, 1899
[PDF, 4MB]
Sachs, Stephan; Goetz, Anna; Finan, Brian; Feuchtinger, Annette; DiMarchi, Richard D.; Doering, Yvonne; Weber, Christian; Tschoep, Matthias H.; Mueller, Timo D. und Hofmann, Susanna M.
(2023):
GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease.
In: Cardiovascular Diabetology, Bd. 22, Nr. 1, 217
[PDF, 1MB]
Mohanta, Sarajo K. K.; Yin, Changjun; Weber, Christian; Godinho-Silva, Cristina; Veiga-Fernandes, Henrique; Xu, Qian J. J.; Chang, Rui B. B. und Habenicht, Andreas J. R.
(2023):
Cardiovascular Brain Circuits.
In: Circulation Research, Bd. 132, Nr. 11: S. 1546-1565
Cimen, Ismail; Natarelli, Lucia; Kichi, Zahra Abedi; Henderson, James M.; Farina, Floriana M.; Briem, Eva; Aslani, Maria; Megens, Remco T. A.; Jansen, Yvonne; Mann-Fallenbuchel, Elizabeth; Gencer, Selin; Duchene, Johan; Nazari-Jahantigh, Maliheh; van der Vorst, Emiel P. C.; Enard, Wolfgang; Doering, Yvonne; Schober, Andreas; Santovito, Donato und Weber, Christian
(2023):
Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice.
In: Science Translational Medicine, Bd. 15, Nr. 720, eadf3357
[PDF, 2MB]
Wagner, Julian U. G.; Tombor, Lukas S.; Malacarne, Pedro Felipe; Kettenhausen, Lisa-Maria; Panthel, Josefine; Kujundzic, Haris; Manickam, Nivethitha; Schmitz, Katja; Cipca, Maria; Stilz, Kathrin A.; Fischer, Ariane; Muhly-Reinholz, Marion; Abplanalp, Wesley T.; John, David; Mohanta, Sarajo K.; Weber, Christian; Habenicht, Andreas J. R.; Buchmann, Giulia K.; Angendohr, Stephan; Amin, Ehsan; Scherschel, Katharina; Kloecker, Nikolaj; Kelm, Malte; Schuettler, Dominik; Clauss, Sebastian; Guenther, Stefan; Boettger, Thomas; Braun, Thomas; Baer, Christian; Pham, Minh-Duc; Krishnan, Jaya; Hille, Susanne; Mueller, Oliver J.; Bozoglu, Tarik; Kupatt, Christian; Nardini, Eleonora; Osmanagic-Myers, Selma; Meyer, Christian; Zeiher, Andreas M.; Brandes, Ralf P.; Luxan, Guillermo und Dimmeler, Stefanie
(2023):
Aging impairs the neurovascular interface in the heart.
In: Science, Bd. 381, Nr. 6660: S. 897-905
Wang, Zhihua; Zhang, Xi; Lu, Shu; Zhang, Chuankai; Ma, Zhe; Su, Rui; Li, Yuanfang; Sun, Ting; Li, Yutao; Hong, Mingyang; Deng, Xinyi; Monjezi, Mohammad Rafiee; Hristov, Michael; Steffens, Sabine; Santovito, Donato; Dornmair, Klaus; Ley, Klaus; Weber, Christian; Mohanta, Sarajo K.; Habenicht, Andreas J. R. und Yin, Changjun
(2023):
Pairing of single-cell RNA analysis and T cell antigen receptor profiling indicates breakdown of T cell tolerance checkpoints in atherosclerosis.
In: Nature Cardiovascular Research, Bd. 2, Nr. 3:
290-+
[PDF, 27MB]
Pekayvaz, Kami; Gold, Christoph; Hoseinpour, Parandis; Engel, Anouk; Martinez-Navarro, Alejandro; Eivers, Luke; Coletti, Raffaele; Joppich, Markus; Dionisio, Flavio; Kaiser, Rainer; Tomas, Lukas; Janjic, Aleksandar; Knott, Maximilian; Mehari, Fitsumbirhan; Polewka, Vivien; Kirschner, Megan; Boda, Annegret; Nicolai, Leo; Schulz, Heiko; Titova, Anna; Kilani, Badr; Lorenz, Michael; Fingerle-Rowson, Gunter; Bucala, Richard; Enard, Wolfgang; Zimmer, Ralf; Weber, Christian; Libby, Peter; Schulz, Christian; Massberg, Steffen und Stark, Konstantin
(2023):
Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation.
In: Immunity, Bd. 56, Nr. 10
[PDF, 9MB]
van Os, Bram W ORCID: https://orcid.org/0000-0002-2327-0527; Vos, Winnie G; Bosmans, Laura A; van Tiel, Claudia M; Lith, Sanne C; den Toom, Myrthe S; Beckers, Linda; Levels, Johannes H M; van Wouw, Suzanne A E; Zelcer, Noam; Zaal, Esther A; Berkers, Celia R; van der Lest, Chris H A; Helms, J Bernd; Weber, Christian ORCID: https://orcid.org/0000-0003-4610-8714; Atzler, Dorothee; de Winther, Menno P J; Baardman, Jeroen; Lutgens, Esther und Ketelhuth, Daniel FJ
(2023):
Hyperlipidaemia elicits an atypical, T helper 1–like CD4+ T-cell response: a key role for very low-density lipoprotein.
In: European Heart Journal Open, Bd. 3, Nr. 2
[PDF, 2MB]
Krammer, Christine; Yang, Bishan; Reichl, Sabrina; Besson‐Girard, Simon ORCID: https://orcid.org/0000-0003-1194-5256; Ji, Hao; Bolini, Verena; Schulte, Corinna; Noels, Heidi; Schlepckow, Kai; Jocher, Georg; Werner, Georg; Willem, Michael; El Bounkari, Omar ORCID: https://orcid.org/0000-0002-3051-2096; Kapurniotu, Aphrodite ORCID: https://orcid.org/0000-0001-6124-7232; Gokce, Ozgun; Weber, Christian; Mohanta, Sarajo ORCID: https://orcid.org/0000-0001-6144-4092 und Bernhagen, Jürgen ORCID: https://orcid.org/0000-0003-2996-2652
(2023):
Pathways linking aging and atheroprotection in Mif‐deficient atherosclerotic mice.
In: The FASEB Journal, Bd. 37, Nr. 3
[PDF, 12MB]
Petzold, Tobias ORCID: https://orcid.org/0000-0001-7805-5632; Zhang, Zhe; Ballesteros, Iván; Saleh, Inas; Polzin, Amin; Thienel, Manuela; Liu, Lulu; Ul Ain, Qurrat; Ehreiser, Vincent; Weber, Christian; Kilani, Badr; Mertsch, Pontus; Götschke, Jeremias; Cremer, Sophie; Fu, Wenwen; Lorenz, Michael; Ishikawa-Ankerhold, Hellen; Raatz, Elisabeth; El-Nemr, Shaza; Görlach, Agnes; Marhuenda, Esther; Stark, Konstantin; Pircher, Joachim; Stegner, David; Gieger, Christian; Schmidt-Supprian, Marc; Gaertner, Florian; Almendros, Isaac; Kelm, Malte; Schulz, Christian; Hidalgo, Andrés und Massberg, Steffen ORCID: https://orcid.org/0000-0001-7387-3986
(2022):
Neutrophil “plucking” on megakaryocytes drives platelet production and boosts cardiovascular disease.
In: Immunity, Bd. 55: S. 1-15
[PDF, 4MB]
Brandhofer, Markus ORCID: https://orcid.org/0000-0002-1629-8353; Hoffmann, Adrian; Blanchet, Xavier ORCID: https://orcid.org/0000-0001-7936-3848; Siminkovitch, Elena; Rohlfing, Anne-Katrin ORCID: https://orcid.org/0000-0001-5469-3648; El Bounkari, Omar ORCID: https://orcid.org/0000-0002-3051-2096; Nestele, Jeremy A.; Bild, Alexander; Kontos, Christos; Hille, Kathleen; Rohde, Vanessa; Fröhlich, Adrian; Golemi, Jona; Gokce, Ozgun; Krammer, Christine; Scheiermann, Patrick ORCID: https://orcid.org/0000-0001-7334-3096; Tsilimparis, Nikolaos; Sachs, Nadja; Kempf, Wolfgang E.; Maegdefessel, Lars; Otabil, Michael K.; Megens, Remco T. A. ORCID: https://orcid.org/0000-0001-9871-6696; Ippel, Hans; Koenen, Rory R. ORCID: https://orcid.org/0000-0002-9955-9730; Luo, Junfu; Engelmann, Bernd; Mayo, Kevin H.; Gawaz, Meinrad; Kapurniotu, Aphrodite; Weber, Christian ORCID: https://orcid.org/0000-0003-4610-8714; Hundelshausen, Philipp von und Bernhagen, Jürgen ORCID: https://orcid.org/0000-0003-2996-2652
(2022):
Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation.
In: Cellular and Molecular Life Sciences, Bd. 79, Nr. 10
[PDF, 3MB]
Gencer, Selin; Doering, Yvonne; Jansen, Yvonne; Bayasgalan, Soyolmaa; Yan, Yi; Bianchini, Mariaelvy; Cimen, Ismail; Mueller, Madeleine; Peters, Linsey J. F.; Megens, Remco T. A.; Hundelshausen, Philipp von; Duchene, Johan; Lemnitzer, Patricia; Soehnlein, Oliver; Weber, Christian und Vorst, Emiel P. C. van der
(2022):
Endothelial ACKR3 drives atherosclerosis by promoting immune cell adhesion to vascular endothelium.
In: Basic Research in Cardiology, Bd. 117, Nr. 1, 30
[PDF, 5MB]
Egea, Virginia; Megens, Remco Theodorus Adrianus; Santovito, Donato; Wantha, Sarawuth; Brandl, Richard; Siess, Wolfgang; Khani, Sajjad; Soehnlein, Oliver; Bartelt, Alexander; Weber, Christian und Ries, Christian
(2022):
Properties and fate of human mesenchymal stem cells upon miRNA let-7f-promoted recruitment to atherosclerotic plaques.
In: Cardiovascular Research, Bd. 119, Nr. 1: S. 155-166
[PDF, 6MB]
Bosmans, Laura A.; Tiel, Claudia M. van; Aarts, Suzanne A. B. M.; Willemsen, Lisa; Baardman, Jeroen; Os, Bram W. van; Toom, Myrthe den; Beckers, Linda; Ahern, David J.; Levels, Johannes H. M.; Jongejan, Aldo; Moerland, Perry D.; Verberk, Sanne G. S.; Bossche, Jan van den; Winther, Menno M. P. J. de; Weber, Christian; Atzler, Dorothee; Monaco, Claudia; Gerdes, Norbert; Shami, Annelie und Lutgens, Esther
(2022):
Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state.
In: Cardiovascular Research, Bd. 119, Nr. 5: S. 1146-1160
[PDF, 1MB]
Evans, Paul C.; Davidson, Sean M.; Wojta, Johann; Baeck, Magnus; Bollini, Sveva; Brittan, Mairi; Catapano, Alberico L.; Chaudhry, Bill; Cluitmans, Matthijs; Gnecchi, Massimiliano; Guzik, Tomasz J.; Hoefer, Imo; Madonna, Rosalinda; Monteiro, Joao P.; Morawietz, Henning; Osto, Elena; Padro, Teresa; Sluimer, Judith C.; Tocchetti, Carlo Gabriele; Heiden, Kim van der; Vilahur, Gemma; Waltenberger, Johannes und Weber, Christian
(2022):
From novel discovery tools and biomarkers to precision medicine-basic cardiovascular science highlights of 2021/22.
In: Cardiovascular Research, Bd. 118, Nr. 13: S. 2754-2767
[PDF, 2MB]
Nitz, Katrin; Lacy, Michael; Bianchini, Mariaelvy; Wichapong, Kanin; Kücükgöze, Irem Avcilar; Bonfiglio, Cecilia A.; Migheli, Roberta; Wu, Yuting; Burger, Carina; Li, Yuanfang; Forne, Ignasi; Ammar, Constantin; Janjic, Aleksandar; Mohanta, Sarajo; Duchene, Johan; Heemskerk, Johan W. M.; Megens, Remco T. A.; Schwedhelm, Edzard; Huveneers, Stephan; Lygate, Craig A.; Santovito, Donato; Zimmer, Ralf; Imhof, Axel; Weber, Christian; Lutgens, Esther und Atzler, Dorothee
(2022):
The Amino Acid Homoarginine Inhibits Atherogenesis by Modulating T-Cell Function.
In: Circulation Research, Bd. 131, Nr. 8: S. 701-712
Leberzammer, Julian; Agten, Stijn M.; Blanchet, Xavier; Duan, Rundan; Ippel, Hans; Megens, Remco T. A.; Schulz, Christian; Aslani, Maria; Duchene, Johan; Doring, Yvonne; Jooss, Natalie J.; Zhang, Pengyu; Brandl, Richard; Stark, Konstantin; Siess, Wolfgang; Jurk, Kerstin; Heemskerk, Johan W. M.; Hackeng, Tilman M.; Mayo, Kevin H.; Weber, Christian und Hundelshausen, Philipp von
(2022):
Targeting platelet-derived CXCL12 impedes arterial thrombosis.
In: Blood, Bd. 139, Nr. 17: S. 2691-2705
[PDF, 1MB]
Liu, Yan; Shi, Jun-Zhuo; Jiang, Rong; Liu, Shao-Fei; He, Yang-Yang; Vorst, Emiel P. C. van der; Weber, Christian; Döring, Yvonne und Yan, Yi
(2022):
Regulatory T Cell-Related Gene Indicators in Pulmonary Hypertension.
In: Frontiers in Pharmacology, Bd. 13, 908783
[PDF, 3MB]
Hettwer, Jan; Hinterdobler, Julia; Miritsch, Benedikt; Deutsch, Marcus-Andre; Li, Xinghai; Mauersberger, Carina; Moggio, Aldo; Braster, Quinte; Gram, Hermann; Robertson, Avril A. B.; Cooper, Matthew A.; Gross, Olaf; Krane, Markus; Weber, Christian; Koenig, Wolfgang; Soehnlein, Oliver; Adamstein, Nicholas H.; Ridker, Paul; Schunkert, Heribert; Libby, Peter; Kessler, Thorsten und Sager, Hendrik B.
(2022):
Interleukin-1 beta suppression dampens inflammatory leucocyte production and uptake in atherosclerosis.
In: Cardiovascular Research, Bd. 118, Nr. 13, cvab337: S. 2778-2791
[PDF, 2MB]
Tas, Karin; Dalla Volta, Beatrice; Lindner, Christina; El Bounkari, Omar; Hille, Kathleen; Tian, Yuan; Puig-Bosch, Xenia; Ballmann, Markus; Hornung, Simon; Ortner, Martin; Prem, Sophia; Meier, Laura; Rammes, Gerhard; Haslbeck, Martin; Weber, Christian; Megens, Remco T. A.; Bernhagen, Juergen und Kapurniotu, Aphrodite
(2022):
Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly.
In: Nature Communications, Bd. 13, Nr. 1, 5004
[PDF, 9MB]
Mohanta, Sarajo K.; Peng, Li; Li, Yuanfang; Lu, Shu; Sun, Ting; Carnevale, Lorenzo; Perrotta, Marialuisa; Ma, Zhe; Forstera, Benjamin; Stanic, Karen; Zhang, Chuankai; Zhang, Xi; Szczepaniak, Piotr; Bianchini, Mariaelvy; Saeed, Borhan R.; Carnevale, Raimondo; Hu, Desheng; Nosalski, Ryszard; Pallante, Fabio; Beer, Michael; Santovito, Donato; Erturk, Ali; Mettenleiter, Thomas C.; Klupp, Barbara G.; Megens, Remco T. A.; Steffens, Sabine; Pelisek, Jaroslav; Eckstein, Hans-Henning; Kleemann, Robert; Habenicht, Livia; Mallat, Ziad; Michel, Jean-Baptiste; Bernhagen, Jürgen; Dichgans, Martin; D'Agostino, Giuseppe; Guzik, Tomasz J.; Olofsson, Peder S.; Yin, Changjun; Weber, Christian; Lembo, Giuseppe; Carnevale, Daniela und Habenicht, Andreas J. R.
(2022):
Neuroimmune cardiovascular interfaces control atherosclerosis.
In: Nature, Bd. 605, Nr. 7908: S. 152-159
[PDF, 100MB]
Habenicht, Livia K. L.; Wang, Zhihua; Zhang, Xi; Li, Yuanfang; Mogler, Carolin; Huspenina, Julia Slotta; Schmid, Roland M.; Weber, Christian; Mohanta, Sarajo K.; Ma, Zhe und Yin, Changjun
(2022):
The C1q-ApoE complex: A new hallmark pathology of viral hepatitis and nonalcoholic fatty liver disease.
In: Frontiers in Immunology, Bd. 13, 970938
[PDF, 13MB]
Peters, Linsey J. F.; Baaten, Constance C. F. M. J.; Maas, Sanne L.; Lu, Chang; Nagy, Magdolna; Jooss, Natalie J.; Bidzhekov, Kiril; Santovito, Donato; Moreno-Andres, Daniel; Jankowski, Joachim; Biessen, Erik A. L.; Doering, Yvonne; Heemskerk, Johan W. M.; Weber, Christian; Kuijpers, Marijke J. E. und Vorst, Emiel P. C. van der
(2022):
MicroRNA-26b Attenuates Platelet Adhesion and Aggregation in Mice.
In: Biomedicines, Bd. 10, Nr. 5, 983
[PDF, 1MB]
Bozoglu, Tarik; Lee, Seungmin; Ziegler, Tilman; Jurisch, Victoria; Maas, Sanne; Baehr, Andrea; Hinkel, Rabea; Hoenig, Amelie; Hariharan, Anjana; Kim, Christina Inyeop; Decker, Simon; Sami, Haider; Koppara, Tobias; Oellinger, Ruppert; Müller, Oliver J.; Frank, Derk; Megens, Remco; Nelson, Peter; Weber, Christian; Schnieke, Angelika; Sperandio, Markus; Santamaria, Gianluca; Rad, Roland; Moretti, Alessandra; Laugwitz, Karl-Ludwig; Soehnlein, Oliver; Ogris, Manfred und Kupatt, Christian
(2022):
Endothelial Retargeting of AAV9 In Vivo.
In: Advanced Science, Bd. 9, Nr. 7, 2103867
Asare, Yaw ORCID: https://orcid.org/0000-0002-8946-5650; Shnipova, Margarita; Živković, Luka; Schlegl, Christina ORCID: https://orcid.org/0000-0001-7314-5954; Tosato, Federica ORCID: https://orcid.org/0000-0002-2783-4764; Aronova, Arailym ORCID: https://orcid.org/0000-0002-1337-2415; Brandhofer, Markus; Strohm, Laura; Beaufort, Nathalie; Malik, Rainer; Weber, Christian ORCID: https://orcid.org/0000-0003-4610-8714; Bernhagen, Jürgen ORCID: https://orcid.org/0000-0003-2996-2652 und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2022):
IKKβ binds NLRP3 providing a shortcut to inflammasome activation for rapid immune responses.
In: Signal Transduction and Targeted Therapy, Bd. 7, 355
[PDF, 1MB]
Guillamat-Prats, Raquel; Hering, Daniel; Derle, Abhishek; Rami, Martina; Haerdtner, Carmen; Santovito, Donato; Rinne, Petteri; Bindila, Laura; Hristov, Michael; Pagano, Sabrina; Vuilleumier, Nicolas; Schmid, Sofie; Janjic, Aleksandar; Enard, Wolfgang; Weber, Christian; Maegdefessel, Lars; Faussner, Alexander; Hilgendorf, Ingo und Steffens, Sabine
(2022):
GPR55 in B cells limits atherosclerosis development and regulates plasma cell maturation.
In: Nature Cardiovascular Research, Bd. 1, Nr. 11:
1056-+
[PDF, 8MB]
Rot, Antal; Gutjahr, Julia C.; Biswas, Aindrila; Aslani, Maria; Hub, Elin; Thiriot, Aude; von Andrian, Ulrich H.; Megens, Remco T. A.; Weber, Christian und Duchene, Johan
(2022):
Murine bone marrow macrophages and human monocytes do not express atypical chemokine receptor 1.
In: Cell Stem Cell, Bd. 29, Nr. 7: S. 1013-1015
He, Yang-Yang; Xie, Xin-Mei; Zhang, Hong-Da; Ye, Jue; Gencer, Selin; Vorst, Emiel P. C. van der; Doering, Yvonne; Weber, Christian; Pang, Xiao-Bin; Jing, Zhi-Cheng; Yan, Yi und Han, Zhi-Yan
(14. Dezember 2021):
Identification of Hypoxia Induced Metabolism Associated Genes in Pulmonary Hypertension.
In: Frontiers in Pharmacology, Bd. 12, 753727
[PDF, 2MB]
Duan, Rundan; Goldmann, Luise; Brandl, Richard; Spannagl, Michael; Weber, Christian; Siess, Wolfgang und Hundelshausen, Philipp von
(24. September 2021):
Effects of the Btk-Inhibitors Remibrutinib (LOU064) and Rilzabrutinib (PRN1008) With Varying Btk Selectivity Over Tec on Platelet Aggregation and in vitro Bleeding Time.
In: Frontiers in Cardiovascular Medicine, Bd. 8, 749022
[PDF, 2MB]
Vorst, Emiel P. C. van der; Pepe, Mario A. A.; Peters, Linsey J. F.; Haberbosch, Markus; Jansen, Yvonne; Naumann, Ronald; Stathopoulos, Georgios T.; Weber, Christian und Bidzhekov, Kiril
(2021):
Transcriptome signature of miRNA-26b KO mouse model suggests novel targets.
In: BMC genomic data, Bd. 22, Nr. 1, 23
[PDF, 2MB]
Alexander, Yvonne; Osto, Elena; Schmidt-Trucksäss, Arno; Shechter, Michael; Trifunovic, Danijela; Duncker, Dirk J.; Aboyans, Victor; Bäck, Magnus; Badimon, Lina; Cosentino, Francesco; De Carlo, Marco; Dorobantu, Maria; Harrison, David G.; Guzik, Tomasz J.; Hoefer, Imo; Morris, Paul D.; Norata, Giuseppe D.; Suades, Rosa; Taddei, Stefano; Vilahur, Gemma; Waltenberger, Johannes; Weber, Christian; Wilkinson, Fiona; Bochaton-Piallat, Marie-Luce und Evans, Paul C.
(2021):
Endothelial function in cardiovascular medicine: a consensus paper of the European Society of Cardioloy working Groups on Artherosclerosis and Vascular Biology, Aorta and Perirpheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis.
In: Cardiovascular Research, Bd. 117, Nr. 1: S. 29-42
Davidson, Sean M.; Padro, Teresa; Bollini, Sveva; Vilahur, Gemma; Duncker, Dirk J.; Evans, Paul C.; Guzik, Tomasz; Hoefer, Imo E.; Waltenberger, Johannes; Wojta, Johann und Weber, Christian
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Progress in cardiac research: from rebooting cardiac regeneration to a complete cell atlas of the heart.
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Gencer, Selin; Doering, Yvonne; Jansen, Yvonne; Bayasgalan, Soyolmaa; Schengel, Olga; Mueller, Madeleine; Peters, Linsey J. F.; Weber, Christian und Vorst, Emiel P. C. van der
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Adipocyte-Specific ACKR3 Regulates Lipid Levels in Adipose Tissue.
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Hinkel, Rabea; Batkai, Sandor; Baehr, Andrea; Bozoglu, Tarik; Straub, Sarah; Borchert, Tobias; Viereck, Janika; Howe, Andrea; Hornaschewitz, Nadja; Oberberger, Lisa; Jurisch, Victoria; Kozlik-Feldmann, Rainer; Freudenthal, Franz; Ziegler, Tilman; Weber, Christian; Sperandio, Markus; Engelhardt, Stefan; Laugwitz, Karl Ludwig; Moretti, Alessandra; Klymiuk, Nik; Thum, Thomas und Kupatt, Christian
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AntimiR-132 Attenuates Myocardial Hypertrophy in an Animal Model of Percutaneous Aortic Constriction.
In: Journal of the American College of Cardiology, Bd. 77, Nr. 23: S. 2923-2935
Hinterdobler, Julia; Schott, Simin; Jin, Hong; Meesmann, Almut; Steinsiek, Anna-Lena; Zimmermann, Anna-Sophia; Wobst, Jana; Mueller, Philipp; Mauersberger, Carina; Vilne, Baiba; Baecklund, Alexandra; Chen, Chien-Sin; Moggio, Aldo; Braster, Quinte; Molitor, Michael; Krane, Markus; Kempf, Wolfgang E.; Ladwig, Karl-Heinz; Hristov, Michael; Hulsmans, Maarten; Hilgendorf, Ingo; Weber, Christian; Wenzel, Philip; Scheiermann, Christoph; Maegdefessel, Lars; Soehnlein, Oliver; Libby, Peter; Nahrendorf, Matthias; Schunkert, Heribert; Kessler, Thorsten und Sager, Hendrik B.
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Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis.
In: European Heart Journal, Bd. 42, Nr. 39: S. 4077-4088
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Lacy, Michael; Buerger, Christina; Shami, Annelie; Ahmadsei, Maiwand; Winkels, Holger; Nitz, Katrin; Tiel, Claudia M. van; Seijkens, Tom T. P.; Kusters, Pascal J. H.; Karshovka, Ela; Prange, Koen H. M.; Wu, Yuting; Brouns, Sanne L. N.; Unterlugauer, Sigrid; Kuijpers, Marijke J. E.; Reiche, Myrthe E.; Steffens, Sabine; Edsfeldt, Andreas; Megens, Remco T. A.; Heemskerk, Johan W. M.; Goncalves, Isabel; Weber, Christian; Gerdes, Norbert; Atzler, Dorothee und Lutgens, Esther
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Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease.
In: Nature Communications, Bd. 12, Nr. 1, 3754
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Natarelli, Lucia; Parca, Luca; Mazza, Tommaso; Weber, Christian; Virgili, Fabio und Fratantonio, Deborah
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MicroRNAs and Long Non-Coding RNAs as Potential Candidates to Target Specific Motifs of SARS-CoV-2.
In: Non-Coding Rna, Bd. 7, Nr. 1, 14
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Santovito, Donato; Toto, Lisa; De Nardis, Velia; Marcantonio, Pamela; D'Aloisio, Rossella; Mastropasqua, Alessandra; De Cesare, Domenico; Bucci, Marco; Paganelli, Camilla; Natarelli, Lucia; Weber, Christian; Consoli, Agostino; Mastropasqua, Rodolfo und Cipollone, Francesco
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Plasma microRNA signature associated with retinopathy in patients with type 2 diabetes.
In: Scientific Reports, Bd. 11, Nr. 1, 4136
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Schober, Andreas; Blay, Richard M.; Saboor Maleki, Saffiyeh; Zahedi, Farima; Winklmaier, Anja E.; Kakar, Mati Y.; Baatsch, Isabelle M.; Zhu, Mengyu; Geissler, Claudia; Fusco, Anja E.; Eberlein, Anna; Li, Nan; Megens, Remco T. A.; Banafsche, Ramin; Kumbrink, Jörg; Weber, Christian und Nazari-Jahantigh, Maliheh
(2021):
MicroRNA-21 Controls Circadian Regulation of Apoptosis in Atherosclerotic Lesions.
In: Circulation, Bd. 144, Nr. 13: S. 1059-1073
Sundararaman, Sai Sahana; Peters, Linsey J. F.; Jansen, Yvonne; Gencer, Selin; Yan, Yi; Nazir, Sumra; Marquez, Andrea Bonnin; Kahles, Florian; Lehrke, Michael; Biessen, Erik A. L.; Jankowski, Joachim; Weber, Christian; Doering, Yvonne und Vorst, Emiel P. C. van der
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Adipocyte calcium sensing receptor is not involved in visceral adipose tissue inflammation or atherosclerosis development in hyperlipidemic Apoe(-/-) mice.
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Vorst, Emiel P. C. van der; Pepe, Mario A. A.; Peters, Linsey J. F.; Haberbosch, Markus; Jansen, Yvonne; Nauman, Ronald; Stathopoulos, Georgios T.; Weber, Christian und Bidzhekov, Kiril
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Transcriptome signature of miRNA-26b KO mouse model suggests novel targets.
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Egea, Virginia; Kessenbrock, Kai; Lawson, Devon; Bartelt, Alexander; Weber, Christian und Ries, Christian
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Let-7f miRNA regulates SDF-1α- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release.
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A MIF-Derived Cyclopeptide that Inhibits MIF Binding and Atherogenic Signaling via the Chemokine Receptor CXCR2.
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Tilstam, Pathricia V.; Soppert, Josefin; Hemmers, Christian; Harlacher, Eva; Döring, Yvonne; Vorst, Emiel P. C. van der; Schulte, Corinna; Alampour-Rajabi, Setareh; Theelen, Wendy; Asare, Yaw; Winther, Menno P. J. de; Lawrence, Toby; Bernhagen, Jürgen; Schober, Andreas; Zernecke, Alma; Jankowski, Joachim; Weber, Christian und Noels, Heidi
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Non-activatable mutant of inhibitor of kappa B kinase alpha (IKK alpha) exerts vascular site-specific effects on atherosclerosis in Apoe-deficient mice.
In: Atherosclerosis, Bd. 292: S. 23-30
Santovito, Donato; Marcantonio, Pamela; Mastroiacovo, Daniela; Natarelli, Lucia; Mandolini, Claudia; De Nardis, Velia; Paganelli, Camilla; De Cesare, Domenico; Affaitati, Giannapia; Giamberardino, Maria Adele; Stellin, Luisa; Pinelli, Mauro; Weber, Christian; De Blasis, Giovanni; Occhiuzzi, Umberto; Bucci, Marco; Desideri, Giovambattista und Cipollone, Francesco
(2020):
High dose rosuvastatin increases ABCA1 transporter in human atherosclerotic plaques in a cholesterol-independent fashion.
In: International Journal of Cardiology, Bd. 299: S. 249-253
Hinkel, Rabea; Ramanujam, Deepak; Kaczmarek, Veronika; Howe, Andrea; Klett, Katharina; Beck, Christina; Dueck, Anne; Thum, Thomas; Laugwitz, Karl-Ludwig; Maegdefessel, Lars; Weber, Christian; Kupatt, Christian und Engelhardt, Stefan
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AntimiR-21 Prevents Myocardial Dysfunction in a Pig Model of Ischemia/Reperfusion Injury.
In: Journal of the American College of Cardiology, Bd. 75, Nr. 15: S. 1788-1800
Kontos, Christos; El Bounkari, Omar; Krammer, Christine; Sinitski, Dzmitry; Hille, Kathleen; Zan, Chunfang; Yan, Guangyao; Wang, Sijia; Gao, Ying; Brandhofer, Markus; Megens, Remco T. A.; Hoffmann, Adrian; Pauli, Jessica; Asare, Yaw; Gerra, Simona; Bourilhon, Priscila; Leng, Lin; Eckstein, Hans-Henning; Kempf, Wolfgang E.; Pelisek, Jaroslav; Gokce, Ozgun; Maegdefessel, Lars; Bucala, Richard; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Weber, Christian; Kapurniotu, Aphrodite und Bernhagen, Jürgen
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Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting.
In: Nature Communications, Bd. 11, Nr. 1, 5981
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Adrover, Jose M.; Aroca-Crevillen, Alejandra; Crainiciuc, Georgiana; Ostos, Fernando; Rojas-Vega, Yeny; Rubio-Ponce, Andrea; Cilloniz, Catia; Bonzon-Kulichenko, Elena; Calvo, Enrique; Rico, Daniel; Moro, Maria A.; Weber, Christian; Lizasoain, Ignacio; Torres, Antoni; Ruiz-Cabello, Jesus; Vazquez, Jesus und Hidalgo, Andres
(2020):
Programmed 'disarming' of the neutrophil proteome reduces the magnitude of inflammation.
In: Nature Immunology, Bd. 21, Nr. 2: S. 135-144
Zhang, Danmei; Ebrahim, Mariam; Adler, Kristin; Blanchet, Xavier; Jamasbi, Janina; Megens, Remco T. A.; Uhland, Kerstin; Ungerer, Martin; Muench, Goetz; Deckmyn, Hans; Weber, Christian; Elia, Natalie; Lorenz, Reinhard und Siess, Wolfgang
(2020):
Glycoprotein VI is not a Functional Platelet Receptor for Fibrin Formed in Plasma or Blood.
In: Thrombosis and Haemostasis, Bd. 120, Nr. 6: S. 977-993
Bernlochner, Isabell; Klug, Melissa; Larasati, Ditya; Scheidt, Moritz von; Santovito, Donato; Hristov, Michael; Weber, Christian; Laugwitz, Karl-Ludwig und Bongiovanni, Dario
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Sorting and magnetic-based isolation of reticulated platelets from peripheral blood.
In: Platelets, Bd. 32, Nr. 1: S. 113-119
Santovito, Donato; Egea, Virginia; Bidzhekov, Kiril; Natarelli, Lucia; Mourao, Andre; Blanchet, Xavier; Wichapong, Kanin; Aslani, Maria; Brunssen, Coy; Horckmans, Michael; Hristov, Michael; Geerlof, Arie; Lutgens, Esther; Daemen, Mat J. A. P.; Hackeng, Tilman; Ries, Christian; Chavakis, Triantafyllos; Morawietz, Henning; Naumann, Ronald; Hundelshausen, Philipp von; Steffens, Sabine; Duchene, Johan; Megens, Remco T. A.; Sattler, Michael und Weber, Christian
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Autophagy unleashes noncanonical microRNA functions.
In: Autophagy, Bd. 16, Nr. 12: S. 2294-2296
Kiouptsi, Klytaimnistra; Pontarollo, Giulia; Todorov, Hristo; Braun, Johannes; Jäckel, Sven; Koeck, Thomas; Bayer, Franziska; Karwot, Cornelia; Karpi, Angelica; Gerber, Susanne; Jansen, Yvonne; Wild, Philipp; Ruf, Wolfram; Daiber, Andreas; Vorst, Emiel van der; Weber, Christian; Döring, Yvonne und Reinhardt, Christoph
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Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice.
In: Gut Microbes, Bd. 11, Nr. 6: S. 1809-1823
Shami, Annelie; Atzler, Dorothee; Bosmans, Laura A.; Winkels, Holger; Meiler, Svenja; Lacy, Michael; Tiel, Claudia van; Megens, Remco Ta; Nitz, Katrin; Baardman, Jeroen; Kusters, Pascal; Seijkens, Tom; Buerger, Christina; Janjic, Aleksandar; Riccardi, Carlo; Edsfeldt, Andreas; Monaco, Claudia; Daemen, Mat; Winther, Menno P. J. de; Nilsson, Jan; Weber, Christian; Gerdes, Norbert; Goncalves, Isabel und Lutgens, Esther
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Glucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans.
In: European Heart Journal, Bd. 41, Nr. 31: S. 2938-2948
Santovito, Donato; Egea, Virginia; Bidzhekov, Kiril; Natarelli, Lucia; Mourao, Andre; Blanchet, Xavier; Wichapong, Kanin; Aslani, Maria; Brunssen, Coy; Horckmans, Michael; Hristov, Michael; Geerlof, Arie; Lutgens, Esther; Daemen, Mat J. A. P.; Hackeng, Tilman M.; Ries, Christian; Chavakis, Triantafyllos; Morawietz, Henning; Naumann, Ronald; Hundelshausen, Philipp von; Steffens, Sabine; Duchene, Johan; Megens, Remco T. A.; Sattler, Michael und Weber, Christian
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Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis.
In: Science Translational Medicine, Bd. 12, Nr. 546, eaaz2294
Hamid, Syed Muhammad; Citir, Mevlut; Terzi, Erdem Murat; Cimen, Ismail; Yildirim, Zehra; Dogan, Asli Ekin; Kocaturk, Begum; Onat, Umut Inci; Arditi, Moshe; Weber, Christian; Traynor-Kaplan, Alexis; Schultz, Carsten und Erbay, Ebru
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Inositol-requiring enzyme-1 regulates phosphoinositide signaling lipids and macrophage growth.
In: EMBO Reports, Bd. 21, Nr. 12, e51462
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Butt, Elke; Stempfle, Katrin; Lister, Lorenz; Wolf, Felix; Kraft, Marcella; Herrmann, Andreas B.; Viciano, Cristina Perpina; Weber, Christian; Hochhaus, Andreas; Ernst, Thomas; Hoffmann, Carsten; Zernecke, Alma und Frietsch, Jochen J.
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Phosphorylation-Dependent Differences in CXCR4-LASP1-AKT1 Interaction between Breast Cancer and Chronic Myeloid Leukemia.
In: Cells, Bd. 9, Nr. 2, 444
Gencer, Selin; Lacy, Michael; Atzler, Dorothee; Vorst, Emiel P. C. van der; Döring, Yvonne und Weber, Christian
(2020):
Immunoinflammatory, Thrombohaemostatic, and Cardiovascular Mechanisms in COVID-19.
In: Thrombosis and Haemostasis, Bd. 120, Nr. 12: S. 1629-1641
Evans, Paul C.; Rainger, G. Ed; Mason, Justin C.; Guzik, Tomasz J.; Osto, Elena; Stamataki, Zania; Neil, Desley; Hoefer, Imo E.; Fragiadaki, Maria; Waltenberger, Johannes; Weber, Christian; Bochaton-Piallat, Marie-Luce und Back, Magnus
(2020):
Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science.
In: Cardiovascular Research, Bd. 116, Nr. 14: S. 2177-2184
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Döring, Yvonne; Jansen, Yvonne; Cimen, Ismail; Aslani, Maria; Gencer, Selin; Peters, Linsey J.F.; Duchene, Johan; Weber, Christian ORCID: https://orcid.org/0000-0003-4610-8714 und van der Vorst, Emiel P.C. ORCID: https://orcid.org/0000-0001-5771-6278
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B-Cell–Specific CXCR4 Protects Against Atherosclerosis Development and Increases Plasma IgM Levels.
In: Circulation Research, Bd. 126, Nr. 6: S. 787-788
Eckardt, Veit; Miller, Michelle C.; Blanchet, Xavier; Duan, Rundan; Leberzammer, Julian; Duchene, Johan; Soehnlein, Oliver; Megens, Remco T. A.; Ludwig, Anna‐Kristin; Dregni, Aurelio; Faussner, Alexander; Wichapong, Kanin; Ippel, Hans; Dijkgraaf, Ingrid; Kaltner, Herbert; Döring, Yvonne; Bidzhekov, Kiril; Hackeng, Tilman M.; Weber, Christian; Gabius, Hans‐Joachim; Hundelshausen, Philipp von und Mayo, Kevin H.
(2020):
Chemokines and galectins form heterodimers to modulate inflammation.
In: Embo Reports, e47852
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Nagy, Magdolna; van Geffen, Johanna P.; Stegner, David; Adams, David J.; Braun, Attila; de Witt, Susanne M.; Elvers, Margitta; Geer, Mitchell J.; Kuijpers, Marijke J. E.; Kunzelmann, Karl; Mori, Jun; Oury, Ccile; Pircher, Joachim; Pleines, Irina; Poole, Alastair W.; Senis, Yotis A.; Verdoold, Remco; Weber, Christian; Nieswandt, Bernhard; Heemskerk, Johan W. M. und Baaten, Constance C. F. M. J.
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Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis.
In: Frontiers in Cardiovascular Medicine, Bd. 6, 99
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Vorst, Emiel P. C. van der; Peters, Linsey J. F.; Müller, Madeleine; Gencer, Selin; Yan, Yi; Weber, Christian und Döring, Yvonne
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G-Protein Coupled Receptor Targeting on Myeloid Cells in Atherosclerosis.
In: Frontiers in Pharmacology, Bd. 10, 531
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Cimen, Ismail; Yildirim, Zehra; Dogan, Asli Ekin; Yildirim, Asli Dilber; Tufanli, Ozlem; Onat, Umut Inci; UyenThao, Nguyen; Watkins, Steven M.; Weber, Christian und Erbay, Ebru
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Double bond configuration of palmitoleate is critical for atheroprotection.
In: Molecular Metabolism, Bd. 28: S. 58-72
Kiouptsi, Klytaimnistra; Jäckel, Sven; Pontarollo, Giulia; Grill, Alexandra; Kuijpers, Marijke J. E.; Wilms, Eivor; Weber, Christian; Sommer, Felix; Nagy, Magdolna; Neideck, Carlos; Jansen, Yvonne; Ascher, Stefanie; Formes, Henning; Karwot, Cornelia; Bayer, Franziska; Kollar, Bettina; Subramaniam, Saravanan; Molitor, Michael; Wenzel, Philip; Rosenstiel, Philip; Todorov, Hristo; Gerber, Susanne; Walter, Ulrich; Jurk, Kerstin; Heemskerk, Johan W. M.; Vorst, Emiel P. C. van der; Döring, Yvonne und Reinhardt, Christoph
(2019):
The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice.
In: Mbio, Bd. 10, Nr. 5, e02298-19
Ketelhuth, Daniel F. J.; Lutgens, Esther; Back, Magnus; Binder, Christoph J.; Van den Bossche, Jan; Daniel, Carolin; Dumitriu, Ingrid E.; Hoefer, Imo; Libby, Peter; O'Neill, Luke; Weber, Christian und Evans, Paul C.
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Immunometabolism and atherosclerosis: perspectives and clinical significance: a position paper from the Working Group on Atherosclerosis and Vascular Biology of the European Society of Cardiology.
In: Cardiovascular Research, Bd. 115, Nr. 9: S. 1385-1392
Vila-Caballer, Marian; Gonzalez-Granado, Jose M.; Zorita, Virginia; Abu Nabah, Yafa N.; Silvestro-Roig, Carlos; del Monte-Monge, Alberto; Molina-Sanchez, Pedro; Ait-Oufella, Hafid; Andres-Manzano, Maria J.; Sanz, Maria J.; Weber, Christian; Kremer, Leonor; Gutierrez, Julio; Mallat, Ziad und Andres, Vicente
(2019):
Disruption of the CCL1-CCR8 axis inhibits vascular Treg recruitment and function and promotes atherosclerosis in mice.
In: Journal of Molecular and Cellular Cardiology, Bd. 132: S. 154-163
Bianchini, Mariaelvy; Duchene, Johan; Santovito, Donato; Schloss, Maximilian J.; Evrard, Maximilien; Winkels, Holger; Aslani, Maria; Mohanta, Sarajo K.; Horckmans, Michael; Blanchet, Xavier; Lacy, Michael; Hundelshausen, Philipp von; Atzler, Dorothee; Habenicht, Andreas; Gerdes, Norbert; Pelisek, Jaroslav; Ng, Lai Guan; Steffens, Sabine; Weber, Christian und Megens, Remco T. A.
(2019):
PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function.
In: Science Immunology, Bd. 4, Nr. 36, eaar3054
Silvestre-Roig, Carlos; Braster, Quinte; Wichapong, Kanin; Lee, Ernest Y.; Marie Teulon, Jean; Berrebeh, Nihel; Winter, Janine; Adrover, Jose M.; Santos, Giancarlo Santiago; Froese, Alexander; Lemnitzer, Patricia; Ortega-Gomez, Almudena; Chevre, Raphael; Marschner, Julian; Schumski, Ariane; Winter, Carla; Perez-Olivares, Laura; Pan, Chang; Paulin, Nicole; Schoufour, Tom; Hartwig, Helene; Gonzalez-Ramos, Silvia; Kamp, Frits; Megens, Remco T. A.; Mowen, Kerri A.; Gunzer, Matthias; Maegdefessel, Lars; Hackeng, Tilman; Lutgens, Esther; Daemen, Mat; Blume, Julia von; Anders, Hans-Joachim; Nikolaev, Viacheslav O.; Pellequer, Jean-Luc; Weber, Christian; Hidalgo, Andres; Nicolaes, Gerry A. F.; Wong, Gerard C. L. und Soehnlein, Oliver
(2019):
Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death.
In: Nature, Bd. 569, Nr. 7755
Vorst, Emiel P. C. van der; Mandl, Manuela; Müller, Madeleine; Neideck, Carlos; Jansen, Yvonne; Hristov, Michael; Gencer, Selin; Peters, Linsey J. F.; Meiler, Svenja; Feld, Micha; Geiselhoeringer, Anna-Lena; Jong, Renske J. de; Ohnmacht, Caspar; Noels, Heidi; Soehnlein, Oliver; Drechsler, Maik; Weber, Christian und Döring, Yvonne
(2019):
Hematopoietic ChemR23 (Chemerin Receptor 23) Fuels Atherosclerosis by Sustaining an M1 Macrophage-Phenotype and Guidance of Plasmacytoid Dendritic Cells to Murine Lesions-Brief Report.
In: Arteriosclerosis Thrombosis and Vascular Biology, Bd. 39, Nr. 4: S. 685-693
Cremer, Sebastian; Michalik, Katharina M.; Fischer, Ariane; Pfisterer, Larissa; Jae, Nicolas; Winter, Carla; Boon, Reinier A.; Muhly-Reinholz, Marion; John, David; Uchida, Shizuka; Weber, Christian; Poller, Wolfgang; Guenther, Stefan; Braun, Thomas; Li, Daniel Y.; Maegdefessel, Lars; Matic, Ljubica Perisic; Hedin, Ulf; Soehnlein, Oliver; Zeiher, Andreas und Dimmeler, Stefanie
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Hematopoietic Deficiency of the Long Noncoding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation.
In: Circulation, Bd. 139, Nr. 10: S. 1320-1334
Schloss, Maximilian J.; Horckmans, Michael; Guillamat-Prats, Raquel; Hering, Daniel; Lauer, Estelle; Lenglet, Sebastien; Weber, Christian; Thomas, Aurelien und Steffens, Sabine
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2-Arachidonoylglycerol mobilizes myeloid cells and worsens heart function after acute myocardial infarction.
In: Cardiovascular Research, Bd. 115, Nr. 3: S. 602-613
Yin, Changjun; Ackermann, Susanne; Ma, Zhe; Mohanta, Sarajo K.; Zhang, Chuankai; Li, Yuanfang; Nietzsche, Sandor; Westermann, Martin; Peng, Li; Hu, Desheng; Bontha, Sai Vineela; Srikakulapu, Prasad; Beer, Michael; Megens, Remco T. A.; Steffens, Sabine; Hildner, Markus; Halder, Luke D.; Eckstein, Hans-Henning; Pelisek, Jaroslav; Herms, Jochen; Roeber, Sigrun; Arzberger, Thomas; Borodovsky, Anna; Habenicht, Livia; Binder, Christoph J.; Weber, Christian; Zipfel, Peter F.; Skerka, Christine und Habenicht, Andreas J. R.
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ApoE attenuates unresolvable inflammation by complex formation with activated C1q.
In: Nature Medicine, Bd. 25, Nr. 3
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Denzinger, Viola; Busygina, Kristina; Jamasbi, Janina; Pekrul, Isabell; Spannagl, Michael; Weber, Christian; Lorenz, Reinhard und Siess, Wolfgang
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Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS-4059, BGB-3111 and Evobrutinib.
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Adrover, Jose M.; del Fresno, Carlos; Crainiciuc, Georgiana; Isabel Cuartero, Maria; Casanova-Acebes, Maria; Weiss, Linnea A.; Huerga-Encabo, Hector; Silvestre-Roig, Carlos; Rossaint, Jan; Cossio, Itziar; Lechuga-Vieco, Ana V.; Garcia-Prieto, Jaime; Gomez-Parrizas, Monica; Quintana, Juan A.; Ballesteros, Ivan; Martin-Salamanca, Sandra; Aroca-Crevillen, Alejandra; Chong, Shu Zhen; Evrard, Maximilien; Balabanian, Karl; Lopez, Jörge; Bidzhekov, Kiril; Bachelerie, Frangoise; Abad-Santos, Francisco; Munoz-Calleja, Cecilia; Zarbock, Alexander; Soehnlein, Oliver; Weber, Christian; Ng, Lai Guan; Lopez-Rodriguez, Cristina; Sancho, David; Moro, Maria A.; Ibanez, Borja und Hidalgo, Andres
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A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.
In: Immunity, Bd. 50, Nr. 2
Prats, Raquel Guillamat; Rami, Martina; Ring, Larisa; Rinne, Petteri; Lauer, Estelle; Lenglet, Sebastien; Thomas, Aurelien; Pagano, Sabrina; Vuilleumier, Nicolas; Cravatt, Benjamin F.; Weber, Christian; Faussner, Alexander und Steffens, Sabine
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Deficiency of Monoacylglycerol Lipase Enhances IgM Plasma Levels and Limits Atherogenesis in a CB2-Dependent Manner.
In: Thrombosis and Haemostasis, Bd. 119, Nr. 2: S. 348-351
Pfeiler, Susanne; Thakur, Manovriti; Grünauer, Petra; Megens, Remco T. A.; Joshi, Urjita; Coletti, Raffaele; Samara, Verena; Müller-Stoy, Geraldine; Ishikawa-Ankerhold, Hellen; Stark, Konstantin; Klingl, Andreas; Fröhlich, Thomas; Arnold, Georg J.; Woermann, Sonja; Bruns, Christiane J.; Alguel, Hana; Weber, Christian; Massberg, Steffen und Engelmann, Bernd
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CD36-triggered cell invasion and persistent tissue colonization by tumor microvesicles during metastasis.
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Seijkens, Tom T. P.; Poels, Kikkie; Meiler, Svenja; van Tiel, Claudia M.; Kusters, Pascal J. H.; Reiche, Myrthe; Atzler, Dorothee; Winkels, Holger; Tjwa, Marc; Poelman, Hessel; Slutter, Bram; Kuiper, Johan; Gijbels, Marion; Kuivenhoven, Jan Albert; Matic, Ljubica Perisic; Paulsson-Berne, Gabrielle; Hedin, Ulf; Hansson, Goran K.; Nicolaes, Gerry A. F.; Daemen, Mat J. A. P.; Weber, Christian; Gerdes, Norbert; de Winther, Menno P. J. und Lutgens, Esther
(2019):
Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8(+) T cell-mediated macrophage death.
In: European Heart Journal, Bd. 40, Nr. 4
Tunon, Jose; Badimon, Lina; Bochaton-Piallat, Marie-Luce; Cariou, Bertrand; Daemen, Mat J.; Egido, Jesus; Evans, Paul C.; Hoefer, Imo E.; Ketelhuth, Daniel F. J.; Lutgens, Esther; Matter, Christian M.; Monaco, Claudia; Steffens, Sabine; Stroes, Erik; Vindis, Cecile; Weber, Christian und Back, Magnus
(2019):
Identifying the anti-inflammatory response to lipid lowering therapy: a position paper from the working group on atherosclerosis and vascular biology of the European Society of Cardiology.
In: Cardiovascular Research, Bd. 115, Nr. 1: S. 10-19
Goldmann, Luise; Duan, Rundan; Kragh, Thorsten; Wittmann, Georg; Weber, Christian; Lorenz, Reinhard; Hundelshausen, Philipp von; Spannagl, Michael und Siess, Wolfgang
(2019):
Oral Bruton tyrosine kinase inhibitors block activation of the platelet Fc receptor CD32a (Fc gamma RIIA): a new option in HIT?
In: Blood Advances, Bd. 3, Nr. 23: S. 4021-4033
Varasteh, Zohreh; Mohanta, Sarajo; Robu, Stephanie; Braeuer, Miriam; Li, Yuanfang; Omidvari, Negar; Topping, Geoffrey; Sun, Ting; Nekolla, Stephan G.; Richter, Antonia; Weber, Christian; Habenicht, Andreas; Haberkorn, Uwe A. und Weber, Wolfgang A.
(2019):
Molecular Imaging of Fibroblast Activity After Myocardial Infarction Using a Ga-68-Labeled Fibroblast Activation Protein Inhibitor, FAPI-04.
In: Journal of Nuclear Medicine, Bd. 60, Nr. 12: S. 1743-1749
Bongiovanni, Dario; Santamaria, Gianluca; Klug, Melissa; Santovito, Donato; Felicetta, Arianna; Hristov, Michael; Scheidt, Moritz von; Aslani, Maria; Cibella, Javier; Weber, Christian; Moretti, Alessandra; Laugwitz, Karl-Ludwig; Peano, Clelia und Bernlochner, Isabell
(2019):
Transcriptome Analysis of Reticulated Platelets Reveals a Prothrombotic Profile.
In: Thrombosis and Haemostasis, Bd. 119, Nr. 11: S. 1795-1806
Viola, Joana R.; Lemnitzer, Patricia; Paulin, Nicole; Drechsler, Maik; Nazari-Jahantigh, Maliheh; Maas, Sanne L.; Jong, R. J. de; Winter, Janine; Schober, Andreas; Weber, Christian; Atabai, Kamran und Soehnlein, Oliver
(12. März 2018):
Deletion of MFGE8 Inhibits Neointima Formation upon Arterial Damage.
In: Thrombosis and Haemostasis, Bd. 118, Nr. 7: S. 1340-1342
[PDF, 1MB]
Lacy, Michael; Kontos, Christos; Brandhofer, Markus; Hille, Kathleen; Groening, Sabine; Sinitski, Dzmitry; Bourilhon, Priscila; Rosenberg, Eric; Krammer, Christine; Thavayogarajah, Tharshika; Pantouris, Georgios; Bakou, Maria; Weber, Christian; Lolis, Elias; Bernhagen, Jürgen und Kapurniotu, Aphrodite
(2018):
Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4.
In: Scientific Reports, Bd. 8, 5171
[PDF, 4MB]
Merckelbach, Sophie; Vorst, Emiel P. C. van der; Kallmayer, Michael; Rischpler, Christoph; Burgkart, Rainer; Döring, Yvonne; Borst, Gert-Jan de; Schwaiger, Markus; Eckstein, Hans-Henning; Weber, Christian und Pelisek, Jaroslav
(2018):
Expression and Cellular Localization of CXCR4 and CXCL12 in Human Carotid Atherosclerotic Plaques.
In: Thrombosis and Haemostasis, Bd. 118, Nr. 1: S. 195-206
Braza, Mounia S.; Leent, Mandy M. T. van; Lameijer, Marnix; Sanchez-Gaytan, Brenda L.; Arts, Rob J. W.; Perez-Medina, Carlos; Conde, Patricia; Garcia, Mercedes R.; Gonzalez-Perez, Maria; Brahmachary, Manisha; Fay, Francois; Kluza, Ewelina; Kossatz, Susanne; Dress, Regine J.; Salem, Fadi; Rialdi, Alexander; Reiner, Thomas; Boros, Peter; Strijkers, Gustav J.; Calcagno, Claudia C.; Ginhoux, Florent; Marazzi, Ivan; Lutgens, Esther; Nicolaes, Gerry A. F.; Weber, Christian; Swirski, Filip K.; Nahrendorf, Matthias; Fisher, Edward A.; Duivenvoorden, Raphael; Fayad, Zahi A.; Netea, Mihai G.; Mulder, Willem J. M. und Ochando, Jordi
(2018):
Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance.
In: Immunity, Bd. 49, Nr. 5: S. 819-828
Curaj, Adelina; Wu, Zhuojun; Rix, Anne; Gresch, Oliver; Sternkopf, Marieke; Alampour-Rajabi, Setareh; Lammers, Twan; Zandvoort, Marc van; Weber, Christian; Könen, Rory R.; Liehn, Elisa A. und Kiessling, Fabian
(2018):
Molecular Ultrasound Imaging of Junctional Adhesion Molecule A Depicts Acute Alterations in Blood Flow and Early Endothelial Dysregulation.
In: Arteriosclerosis Thrombosis and Vascular Biology, Bd. 38, Nr. 1: S. 40-48
[PDF, 754kB]
Casanova-Acebes, Maria; Nicolas-Avila, Jose A.; Li, Jackson LiangYao; Garcia-Silva, Susana; Balachander, Akhila; Rubio-Ponce, Andrea; Weiss, Linnea A.; Adrover, Jose M.; Burrows, Kyle; A-Gonzalez, Noelia; Ballesteros, Ivan; Devi, Sapna; Quintana, Juan A.; Crainiciuc, Georgiana; Leiva, Magdalena; Gunzer, Matthias; Weber, Christian; Nagasawa, Takashi; Söhnlein, Oliver; Merad, Miriam; Mortha, Arthur; Ng, Lai Guan; Peinado, Hector und Hidalgo, Andres
(2018):
Neutrophils instruct homeostatic and pathological states in naive tissues.
In: Journal of Experimental Medicine, Bd. 215, Nr. 11: S. 2778-2795
Lu, Hong S.; Schmidt, Ann Marie; Hegele, Robert A.; Mackman, Nigel; Rader, Daniel J.; Weber, Christian und Daugherty, Alan
(2018):
Reporting Sex and Sex Differences in Preclinical Studies.
In: Arteriosclerosis Thrombosis and Vascular Biology, Bd. 38, Nr. 10, E171-E184
[PDF, 147kB]
Tunon, Jose; Back, Magnus; Badimon, Lina; Bochaton-Piallat, Marie-Luce; Cariou, Bertrand; Daemen, Mat J.; Egido, Jesus; Evans, Paul C.; Francis, Sheila E.; Ketelhuth, Daniel F. J.; Lutgens, Esther; Matter, Christian M.; Monaco, Claudia; Steffens, Sabine; Strös, Erik; Vindis, Cecile; Weber, Christian und Höfer, Imo E.
(2018):
Interplay between hypercholesterolaemia and inflammation in atherosclerosis: Translating experimental targets into clinical practice.
In: European Journal of Preventive Cardiology, Bd. 25, Nr. 9: S. 948-955
[PDF, 356kB]
Ziegler, Tilman; Kraus, Markus; Husada, Wira; Gesenhues, Florian; Jiang, Qui; Pinkenburg, Olaf; Trenkwalder, Teresa; Laugwitz, Karl-Ludwig; Noble, Ferdinand le; Weber, Christian; Kupatt, Christian und Hinkel, Rabea
(2018):
Steerable Induction of the Thymosin beta 4/MRTF-A Pathway via AAV-Based Overexpression Induces Therapeutic Neovascularization.
In: Human Gene Therapy, Bd. 29, Nr. 12: S. 1407-1415
Domschke, Gabriele; Linden, Fabian; Pawig, Lukas; Hafner, Anna; Akhavanpoor, Mohammadreza; Reymann, Jürgen; Dösch, Andreas O.; Erbel, Christian; Weber, Christian; Katus, Hugo A.; Nöls, Heidi; Erfle, Holger; Gleissner, Christian A. und Runz, Heiko
(2018):
Systematic RNA-interference in primary human monocyte-derived macrophages: A high-throughput platform to study foam cell formation.
In: Scientific Reports, Bd. 8, 10516
[PDF, 1MB]
Ziegler, Tilman; Bähr, Andrea; Howe, Andrea; Klett, Katharina; Husada, Wira; Weber, Christian; Laugwitz, Karl-Ludwig; Kupatt, Christian und Hinkel, Rabea
(2018):
T beta 4 Increases Neovascularization and Cardiac Function in Chronic Myocardial Ischemia of Normo- and Hypercholesterolemic Pigs.
In: Molecular Therapy, Bd. 26, Nr. 7: S. 1706-1714
Stocker, Thomas J.; Pircher, Joachim; Skenderi, Artid; Ehrlich, Andreas; Eberle, Clemens; Megens, Remco T. A.; Petzold, Tobias; Zhang, Zhe; Walzog, Barbara; Müller-Taubenberger, Annette; Weber, Christian; Massberg, Steffen; Ishikawa-Ankerhold, Hellen und Schulz, Christian
(2018):
The Actin Regulator Coronin-1A Modulates Platelet Shape Change and Consolidates Arterial Thrombosis.
In: Thrombosis and Haemostasis, Bd. 118, Nr. 12: S. 2098-2111
Rami, Martina; Guillamat-Prats, Raquel; Rinne, Petteri; Salvermoser, Melanie; Ring, Larisa; Bianchini, Mariaelvy; Blanchet, Xavier; Megens, Remco T. A.; Doering, Yvonne; Walzog, Barbara; Soehnlein, Oliver; Weber, Christian; Faussner, Alexander und Steffens, Sabine
(2018):
Chronic Intake of the Selective Serotonin Reuptake Inhibitor Fluoxetine Enhances Atherosclerosis.
In: Arteriosclerosis Thrombosis and Vascular Biology, Bd. 38, Nr. 5: S. 1007-1019
[PDF, 1MB]
Ebrahim, Mariam; Jamasbi, Janina; Adler, Kristin; Megens, Remco T. A.; M'Bengue, Yacine; Blanchet, Xavier; Uhland, Kerstin; Ungerer, Martin; Brandl, Richard; Weber, Christian; Elia, Natalie; Lorenz, Reinhard; Münch, Götz und Siess, Wolfgang
(2018):
Dimeric Glycoprotein VI Binds to Collagen but Not to Fibrin.
In: Thrombosis and Haemostasis, Bd. 118, Nr. 2: S. 351-361
Schmitz, Corinna; Noels, Heidi; El Bounkari, Omar; Straussfeld, Eva; Megens, Remco T. A.; Sternkopf, Marieke; Alampour-Rajabi, Setareh; Krammer, Christine; Tilstam, Pathricia V.; Gerdes, Norbert; Bürger, Christina; Kapurniotu, Aphrodite; Bucala, Richard; Jankowski, Joachim; Weber, Christian und Bernhagen, Jürgen
(2018):
Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis.
In: FASEB Journal, Bd. 32, Nr. 8: S. 4428-4443
Busygina, Kristina; Jamasbi, Janina; Seiler, Till; Deckmyn, Hans; Weber, Christian; Brandl, Richard; Lorenz, Reinhard und Siess, Wolfgang
(2018):
Oral Bruton tyrosine kinase inhibitors selectively block atherosclerotic plaque-triggered thrombus formation in humans.
In: Blood, Bd. 131, Nr. 24: S. 2605-2616
Rinne, Petteri; Guillamat-Prats, Raquel; Rami, Martina; Bindila, Laura; Ring, Larisa; Lyytikainen, Leo-Pekka; Raitoharju, Emma; Oksala, Niku; Lehtimaki, Terho; Weber, Christian; Vorst, Emiel P. C. van der und Steffens, Sabine
(2018):
Palmitoylethanolamide Promotes a Proresolving Macrophage Phenotype and Attenuates Atherosclerotic Plaque Formation.
In: Arteriosclerosis Thrombosis and Vascular Biology, Bd. 38, Nr. 11: S. 2562-2575
[PDF, 4MB]
Horckmans, Michael; Bianchini, Mariaelvy; Santovito, Donato; Megens, Remco T. A.; Springael, Jean-Yves; Negri, Irene; Vacca, Michele; Di Eusanio, Marco; Moschetta, Antonio; Weber, Christian; Duchene, Johan und Steffens, Sabine
(2018):
Pericardial Adipose Tissue Regulates Granulopoiesis, Fibrosis, and Cardiac Function After Myocardial Infarction.
In: Circulation, Bd. 137, Nr. 9: S. 948-960
[PDF, 7kB]
Nicolaou, Alexandros; Northoff, Bernd H.; Zhao, Zhen; Kohlmaier, Alexander; Sass, Kristina; Rose-John, Stefan; Steffens, Sabine; Weber, Christian; Teupser, Daniel und Holdt, Lesca M.
(2018):
The ADAM17 Metalloproteinase Maintains Arterial Elasticity.
In: Thrombosis and Haemostasis, Bd. 118, Nr. 1: S. 210-213
Winter, Carla; Silvestre-Roig, Carlos; Ortega-Gomez, Almudena; Lemnitzer, Patricia; Poelman, Hessel; Schumski, Ariane; Winter, Janine; Drechsler, Maik; Jong, Renske de; Immler, Roland; Sperandio, Markus; Hristov, Michael; Zeller, Tanja; Nicolaes, Gerry A. F.; Weber, Christian; Viola, Joana R.; Hidalgo, Andres; Scheiermann, Christoph und Soehnlein, Oliver
(2018):
Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis.
In: Cell Metabolism, Bd. 28, Nr. 1: S. 175-182
Baaten, Constance C. F. M. J.; Meacham, Stuart; Witt, Susanne M. de; Feijge, Marion A. H.; Adams, David J.; Akkerman, Jan-Willem N.; Cosemans, Judith M. E. M.; Grassi, Luigi; Jupe, Steve; Kostadima, Myrto; Mattheij, Nadine J. A.; Prins, Martin H.; Ramirez-Solis, Ramiro; Soehnlein, Oliver; Swieringa, Frauke; Weber, Christian; White, Jacqueline K.; Ouwehand, Willem H. und Heemskerk, Johan W. M.
(2018):
A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding.
In: Blood, Bd. 132, Nr. 24, E35-E46
Vajen, Tanja; Koenen, Rory R.; Werner, Isabella; Staudt, Mareike; Projahn, Delia; Curaj, Adelina; Soenmez, Tolga Taha; Simsekyilmaz, Sakine; Schumacher, David; Möllmann, Julia; Hackeng, Tilman M.; Hundelshausen, Philipp von; Weber, Christian und Liehn, Elisa A.
(2018):
Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis.
In: Scientific Reports, Bd. 8, 10647
[PDF, 4MB]
Poller, Wolfgang; Dimmeler, Stefanie; Heymans, Stephane; Zeller, Tanja; Haas, Jan; Karakas, Mahir; Leistner, David-Manuel; Jakob, Philipp; Nakagawa, Shinichi; Blankenberg, Stefan; Engelhardt, Stefan; Thum, Thomas; Weber, Christian; Meder, Benjamin; Hajjar, Roger und Landmesser, Ulf
(2018):
Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives.
In: European Heart Journal, Bd. 39, Nr. 29: S. 2704-2716
Seijkens, Tom T. P.; Tiel, Claudia M. van; Kusters, Pascal J. H.; Atzler, Dorothee; Soehnlein, Oliver; Zarzycka, Barbara; Aarts, Suzanne A. B. M.; Lameijer, Marnix; Gijbels, Marion J.; Beckers, Linda; Toom, Myrthe den; Slutter, Bram; Kuiper, Johan; Duchene, Johan; Aslani, Maria; Megens, Remco T. A.; Veer, Cornelis van 't; Kooij, Gijs; Schrijver, Roy; Hoeksema, Marten A.; Boon, Louis; Fay, Francois; Tang, Jun; Baxter, Samantha; Jongejan, Aldo; Moerland, Perry D.; Vriend, Gert; Bleijlevens, Boris; Fisher, Edward A.; Duivenvoorden, Raphael; Gerdes, Norbert; Winther, Menno P. J. de; Nicolaes, Gerry A.; Mulder, Willem J. M.; Weber, Christian und Lutgens, Esther
(2018):
Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.
In: Journal of the American College of Cardiology, Bd. 71, Nr. 5: S. 527-542
Winkels, Holger; Meiler, Svenja; Lievens, Dirk; Engel, David; Spitz, Charlotte; Bürger, Christina; Beckers, Linda; Dandl, Angelika; Reim, Sigrid; Ahmadsei, Maiwand; Hartwig, Helene; Holdt, Lesca M.; Hristov, Michael; Megens, Remco T. A.; Schmitt, Martin M.; Biessen, Eric A.; Borst, Jannie; Faussner, Alexander; Weber, Christian; Lutgens, Esther und Gerdes, Norbert
(2017):
CD27 co-stimulation increases the abundance of regulatory T cells and reduces atherosclerosis in hyperlipidaemic mice.
In: European Heart Journal, Bd. 38, Nr. 48:
3590-U42
Nicolaou, Alexandros; Zhao, Zhen; Northoff, Bernd H.; Sass, Kristina; Herbst, Andreas; Kohlmaier, Alexander; Chalaris, Athena; Wolfrum, Christian; Weber, Christian; Steffens, Sabine; Rose-John, Stefan; Teupser, Daniel und Holdt, Lesca M.
(2017):
Adam17 Deficiency Promotes Atherosclerosis by Enhanced TNFR2 Signaling in Mice.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 37, Nr. 2: S. 247-257
Winkels, Holger; Meiler, Svenja; Smeets, Esther; Lievens, Dirk; Engel, David; Spitz, Charlotte; Bürger, Christina; Rinne, Petteri; Beckers, Linda; Dandl, Angelika; Reim, Sigrid; Ahmadsei, Maiwand; Bossche, Jan van den; Holdt, Lesca M.; Megens, Remco T. A.; Schmitt, Martin M.; Winther, Menno de; Biessen, Eric A.; Borst, Jannie; Faussner, Alexander; Weber, Christian; Lutgens, Esther und Gerdes, Norbert
(2017):
CD70 limits atherosclerosis and promotes macrophage function.
In: Thrombosis and Haemostasis, Bd. 117, Nr. 1: S. 164-175
Schloss, Maximilian J.; Hilby, Michael; Nitz, Katrin; Prats, Raquel Guillamat; Ferraro, Bartolo; Leoni, Giovanna; Söhnlein, Oliver; Kessler, Thorsten; He, Wenyan; Luckow, Bruno; Horckmans, Michael; Weber, Christian; Duchene, Johan und Steffens, Sabine
(2017):
Ly6C(high) Monocytes Oscillate in the Heart During Homeostasis and After Myocardial Infarction-Brief Report.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 37, Nr. 9: S. 1640-1645
Munoz, Ann-Katrin Mojica; Jamasbi, Janina; Uhland, Kerstin; Degen, Heidrun; Münch, Götz; Ungerer, Martin; Brandl, Richard; Megens, Remco; Weber, Christian; Lorenz, Reinhard und Siess, Wolfgang
(2017):
Recombinant GPVI-Fc added to single or dual antiplatelet therapy in vitro prevents plaque-induced platelet thrombus formation.
In: Thrombosis and Haemostasis, Bd. 117, Nr. 8: S. 1651-1659
Asare, Yaw; Ommer, Miriam; Azombo, Florence. A.; Alampour-Rajabi, Setareh; Sternkopf, Marieke; Sanati, Maryam; Gijbels, Marion J.; Schmitz, Corinna; Sinitski, Dzmitry; Tilstam, Pathricia V.; Lue, Hongqi; Gessner, Andre; Lange, Denise; Schmid, Johannes A.; Weber, Christian; Dichgans, Martin; Jankowski, Joachim; Pardi, Ruggero; Winther, Menno P. J. de; Nöls, Heidi und Bernhagen, Jürgen
(2017):
Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 114, Nr. 13, E2766-E2775
Horckmans, Michael; Ring, Larisa; Duchene, Johan; Santovito, Donato; Schloss, Maximilian J.; Drechsler, Maik; Weber, Christian; Söhnlein, Oliver und Steffens, Sabine
(2017):
Neutrophils orchestrate post-myocardial infarction healing by polarizing macrophages towards a reparative phenotype.
In: European Heart Journal, Bd. 38, Nr. 3: S. 187-197
[PDF, 1MB]
Aarts, Suzanne A. B. M.; Seijkens, Tom T. P.; Kusters, Pascal J. H.; Pol, Susanne M. A. van der; Zarzycka, Barbara; Heijnen, Priscilla D. A. M.; Beckers, Linda; Toom, Myrthe den; Gijbels, Marion J. J.; Boon, Louis; Weber, Christian; Vries, Helga E. de; Nicolaes, Gerry A. F.; Dijkstra, Christine D.; Kooij, Gijs und Lutgens, Esther
(2017):
Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation.
In: Journal of Neuroinflammation
14:105
[PDF, 3MB]
Kusters, Pascal; Seijkens, Tom; Bürger, Christina; Legein, Bart; Winkels, Holger; Gijbels, Marion; Barthels, Christian; Bennett, Remy; Beckers, Linda; Atzler, Dorothee; Biessen, Erik; Brocker, Thomas; Weber, Christian; Gerdes, Norbert und Lutgens, Esther
(2017):
Constitutive CD40 Signaling in Dendritic Cells Limits Atherosclerosis by Provoking Inflammatory Bowel Disease and Ensuing Cholesterol Malabsorption.
In: American Journal of Pathology, Bd. 187, Nr. 12: S. 2912-2919
Bamberg, Fabian; Hetterich, Holger; Rospleszcz, Susanne; Lorbeer, Roberto; Auweter, Sigrid D.; Schlett, Christopher L.; Schafnitzel, Anina; Bayerl, Christian; Schindler, Andreas; Saam, Tobias; Müller-Peltzer, Katharina; Sommer, Wieland; Zitzelsberger, Tanja; Machann, Jürgen; Ingrisch, Michael; Selder, Sonja; Rathmann, Wolfgang; Heier, Margit; Linkohr, Birgit; Meisinger, Christa; Weber, Christian; Ertl-Wagner, Birgit; Massberg, Steffen; Reiser, Maximilian F. und Peters, Annette
(2017):
Subclinical Disease Burden as Assessed by Whole-Body MRI in Subjects With Prediabetes, Subjects With Diabetes, and Normal Control Subjects From the General Population: The KORA-MRI Study.
In: Diabetes, Bd. 66, Nr. 1: S. 158-169
Theodorou, Kosta; Vorst, Emiel P. C. van der; Gijbels, Marion J.; Wolfs, Ine M. J.; Jeurissen, Mike; Theelen, Thomas L.; Sluimer, Judith C.; Wijnands, Erwin; Cleutjens, Jack P.; Li, Yu; Jansen, Yvonne; Weber, Christian; Ludwig, Andreas; Bentzon, Jacob F.; Bartsch, Jörg W.; Biessen, Erik A. L. und Donners, Marjo M. P. C.
(2017):
Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression.
In: Scientific Reports, Bd. 7, 11670
[PDF, 6MB]
Xu, Yiming; Wang, Yong; Yan, Siyuan; Zhou, Yaqi; Yang, Qiuhua; Pan, Yue; Zeng, Xianqiu; An, Xiaofei; Liu, Zhiping; Wang, Lina; Xu, Jiean; Cao, Yapeng; Fulton, David J.; Weintraub, Neal L.; Bagi, Zsolt; Hoda, Md Nasrul; Wang, Xiaoling; Li, Qinkai; Hong, Mei; Jiang, Xuejun; Boison, Detlev; Weber, Christian; Wu, Chaodong und Huo, Yuqing
(2017):
Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis.
In: Embo Molecular Medicine, Bd. 9, Nr. 9: S. 1263-1278
Rinne, Petteri; Rami, Martina; Nuutinen, Salla; Santovito, Donato; Vorst, Emiel P. C. van der; Guillamat-Prats, Raquel; Lyytikainen, Leo-Pekka; Raitoharju, Emma; Oksala, Niku; Ring, Larisa; Cai, Minying; Hruby, Victor J.; Lehtimaki, Terho; Weber, Christian und Steffens, Sabine
(2017):
Melanocortin 1 Receptor Signaling Regulates Cholesterol Transport in Macrophages.
In: Circulation, Bd. 136, Nr. 1: S. 83-97
Ridger, Victoria C.; Boulanger, Chantal M.; Angelillo-Scherrer, Anne; Badimon, Lina; Blanc-Brude, Olivier; Bochaton-Piallat, Marie-Luce; Boilard, Eric; Buzas, Edit I.; Caporali, Andreas; Dignat-George, Francoise; Evans, Paul C.; Lacroix, Romaric; Lutgens, Esther; Ketelhuth, Daniel F. J.; Nieuwland, Rienk; Toti, Florence; Tunon, Jose; Weber, Christian; Höfer, Imo E.; Lip, Gregory Y. H.; Werner, Nikos; Shantsila, Eduard; Cate, Hugo ten; Thomas, Mark und Harrison, Paul
(2017):
Microvesicles in vascular homeostasis and diseases Position Paper of the European Society of Cardiology (ESC) Working Group on Atherosclerosis and Vascular Biology.
In: Thrombosis and Haemostasis, Bd. 117, Nr. 7: S. 1296-1316
Duchene, Johan; Novitzky-Basso, Igor; Thiriot, Aude; Casanova-Acebes, Maria; Bianchini, Mariaelvy; Etheridge, S. Leah; Hub, Elin; Nitz, Katrin; Artinger, Katharina; Eller, Kathrin; Caamano, Jörge; Rulicke, Thomas; Moss, Paul; Megens, Remco T. A.; Andrian, Ulrich H. von; Hidalgo, Andres; Weber, Christian und Rot, Antal
(2017):
Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis.
In: Nature Immunology, Bd. 18, Nr. 7: S. 753-761
Zhao, Zhen; Vajen, Tanja; Karshovska, Ela; Dickhout, Annemiek; Schmitt, Martin M.; Megens, Remco T. A.; Hundelshausen, Philipp von; Köppel, Thomas A.; Hackeng, Tilman M.; Weber, Christian und Könen, Rory R.
(2017):
Deletion of junctional adhesion molecule A from platelets increases early-stage neointima formation after wire injury in hyperlipidemic mice.
In: Journal of Cellular and Molecular Medicine, Bd. 21, Nr. 8: S. 1523-1531
Döring, Yvonne; Noels, Heidi; Vorst, Emiel P. C. van der; Neideck, Carlos; Egea, Virginia; Drechsler, Maik; Mandl, Manuela; Pawig, Lukas; Jansen, Yvonne; Schröder, Katrin; Bidzhekov, Kiril; Megens, Remco T. A.; Theelen, Wendy; Klinkhammer, Barbara M.; Boor, Peter; Schurgers, Leon; Gorp, Rick van; Ries, Christian; Kusters, Pascal J. H.; Wal, Allard van der; Hackeng, Tilman M.; Gäbel, Gabor; Brandes, Ralf P.; Söhnlein, Oliver; Lutgens, Esther; Vestweber, Dietmar; Teupser, Daniel; Holdt, Lesca M.; Rader, Daniel J.; Saleheen, Danish und Weber, Christian
(2017):
Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity Evidence From Mouse and Human Studies.
In: Circulation, Bd. 136, Nr. 4: S. 388-403
[PDF, 3MB]
Hundelshausen, Philipp von; Agten, Stijn M.; Eckardt, Veit; Blanchet, Xavier; Schmitt, Martin M.; Ippel, Hans; Neideck, Carlos; Bidzhekov, Kiril; Leberzammer, Julian; Wichapong, Kanin; Faussner, Alexander; Drechsler, Maik; Grommes, Jochen; Geffen, Johanna P. van; Li, He; Ortega-Gomez, Almudena; Megens, Remco T. A.; Naumann, Ronald; Dijkgraaf, Ingrid; Nicolaes, Gerry A. F.; Döring, Yvonne; Soehnlein, Oliver; Lutgens, Esther; Heemskerk, Johan W. M.; Könen, Rory R.; Mayo, Kevin H.; Hackeng, Tilman M. und Weber, Christian
(2017):
Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.
In: Science Translational Medicine, Bd. 9, Nr. 384, eaah6650
Krishnasamy, Kashyap; Limbourg, Anne; Kapanadze, Tamar; Gamrekelashvili, Jaba; Beger, Christian; Häger, Christine; Lozanovski, Vladimir J.; Falk, Christine S.; Napp, L. Christian; Bauersachs, Johann; Mack, Matthias; Haller, Hermann; Weber, Christian; Adams, Ralf H. und Limbourg, Florian P.
(2017):
Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia.
In: Nature Communications, Bd. 8, 952
[PDF, 3MB]
Seijkens, Tom T.; Winkels, Holger; Gijbels, Marion; Kuivenhoven, Jan A.; Perisic, Ljubica; Paulsson-Berne, Gabrielle; Hedin, Ulf; Hansson, Goran K.; Weber, Christian; Gerdes, Norbert; Winther, Menno P. de und Lutgens, Esther
(2017):
Deficiency of the T Cell Regulator Cbl-B Aggravates Atherosclerosis by Inducing CD8(+) T Cell-Mediated Macrophage Death.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 37
Hyafil, Fabien; Pelisek, Jaroslav; Laitinen, Iina; Schottelius, Margret; Mohring, Miriam; Döring, Yvonne; Vorst, Emiel P. C. van der; Kallmayer, Michael; Steiger, Katja; Poschenrieder, Andreas; Notni, Johannes; Fischer, Johannes; Baumgartner, Christine; Rischpler, Christoph; Nekolla, Stephan G.; Weber, Christian; Eckstein, Hans-Henning; Wester, Hans-Jürgen und Schwaiger, Markus
(2017):
Imaging the Cytokine Receptor CXCR4 in Atherosclerotic Plaques with the Radiotracer Ga-68-Pentixafor for PET.
In: Journal of Nuclear Medicine, Bd. 58, Nr. 3: S. 499-506
Rowinska, Zuzanna; Koeppel, Thomas A.; Sanati, Maryam; Schelzig, Hubert; Jankowski, Joachim; Weber, Christian; Zernecke, Alma und Liehn, Elisa A.
(2017):
Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation.
In: PLOS One
12(2), e0170644
[PDF, 1MB]
Tufanli, Ozlem; Akillilar, Pelin Telkoparan; Acosta-Alvear, Diego; Kocaturk, Begum; Onat, Umut Inci; Hamid, Syed Muhammad; Çimen, Ismail; Walter, Peter; Weber, Christian und Erbay, Ebru
(2017):
Targeting IRE1 with small molecules counteracts progression of atherosclerosis.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 114, Nr. 8, E1395-E1404
Paulin, Nicole; Döring, Yvonne; Kooijman, Sander; Blanchet, Xavier; Viola, Joana R.; Jong, Renske de; Mandl, Manuela; Hendrikse, Jeffrey; Schiener, Maximilian; Hundelshausen, Philipp von; Vogt, Anja; Weber, Christian; Bdeir, Khalil; Hofmann, Susanna M.; Rensen, Patrick C. N.; Drechsler, Maik und Soehnlein, Oliver
(2017):
Human Neutrophil Peptide 1 Limits Hypercholesterolemia-induced Atherosclerosis by Increasing Hepatic LDL Clearance.
In: Ebiomedicine, Bd. 16: S. 204-211
Jong, Renske J. de; Paulin, Nicole; Lemnitzer, Patricia; Viola, Joana R.; Winter, Carla; Ferraro, Bartolo; Grommes, Jochen; Weber, Christian; Reutelingsperger, Chris; Drechsler, Maik und Soehnlein, Oliver
(2017):
Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 37, Nr. 2: S. 312-315
[PDF, 1MB]
Wolf, Dennis; Bukosza, Nora; Enge, David; Poggi, Marjorie; Jehle, Felix; Michel, Nathaly Anto; Chen, Yung-Chih; Colberg, Christian; Hoppe, Natalie; Dufner, Bianca; Boon, Louis; Blankenbach, Hermann; Hilgendorf, Ingo; Muhlen, Constantin Von Zur; Reinoehl, Jochen; Sommer, Björn; Marchini, Timoteo; Febbraio, Mark A.; Weber, Christian; Bode, Christoph; Peter, Karlheinz; Lutgens, Esther und Zirlik, Andreas
(2017):
Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO).
In: Thrombosis and Haemostasis, Bd. 117, Nr. 2: S. 325-338
Feng, Shuang; Bowden, Neil; Fragiadaki, Maria; Souilhol, Celine; Hsiao, Sarah; Mahmoud, Marwa; Allen, Scott; Pirri, Daniela; Ayllon, Blanca Tardajos; Akhtar, Shamima; Thompson, A. A. Roger; Jo, Hanjoong; Weber, Christian; Ridger, Victoria; Schober, Andreas und Evans, Paul C.
(2017):
Mechanical Activation of Hypoxia-Inducible Factor 1 alpha Drives Endothelial Dysfunction at Atheroprone Sites.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 37, Nr. 11: S. 2087-2101
[PDF, 3MB]
Zahedi, Farima; Nazari-Jahantigh, Maliheh; Zhou, Zhe; Subramanian, Pallavi; Wei, Yuanyuan; Grommes, Jochen; Offermanns, Stefan; Steffens, Sabine; Weber, Christian und Schober, Andreas
(2017):
Dicer generates a regulatory microRNA network in smooth muscle cells that limits neointima formation during vascular repair.
In: Cellular and Molecular Life Sciences, Bd. 74, Nr. 2: S. 359-372
Horckmans, Michael; Schloss, Maximilian; Bianchini, Mariaelvy; Megens, Remco; Ring, Larisa; Thomas, Aurelien; Lauer, Estelle; Lenglet, Sebastien; Weber, Christian; Duchene, Johan und Steffens, Sabine
(2017):
The 2-arachidonoylglyercol/cannabinoid receptor 2 axis regulates bone marrow mobilization and myeloid cell recruitment after myocardial infarction.
In: Journal of Vascular Research, Bd. 54: S. 59
Chubanov, Vladimir; Ferioli, Silvia; Wisnowsky, Annika; Simmons, David G.; Leitzinger, Christin; Einer, Claudia; Jonas, Wenke; Shymkiv, Yuriy; Bartsch, Harald; Braun, Attila; Akdogan, Banu; Mittermeier, Lorenz; Sytik, Ludmila; Torben, Friedrich; Jurinovic, Vindi; Vorst, Emiel P. C. van der; Weber, Christian; Yildirim, Önder A.; Sotlar, Karl; Schürmann, Annette; Zierler, Susanna; Zischka, Hans; Ryazanov, Alexey G. und Gudermann, Thomas
(2016):
Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival.
In: eLife, Bd. 5, e20914
[PDF, 3MB]
Schloss, Maximilian J.; Horckmans, Michael; Nitz, Katrin; Duchene, Johan; Drechsler, Maik; Bidzhekov, Kiril; Scheiermann, Christoph; Weber, Christian; Soehnlein, Oliver und Steffens, Sabine
(2016):
The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment.
In: Embo Molecular Medicine, Bd. 8, Nr. 8: S. 937-948
[PDF, 2MB]
Simsekyilmaz, Sakine; Liehn, Elisa A.; Weinandy, Stefan; Schreiber, Fabian; Megens, Remco T. A.; Theelen, Wendy; Smeets, Ralf; Jockenhövel, Stefan; Gries, Thomas; Möller, Martin; Klee, Doris; Weber, Christian und Zernecke, Alma
(2016):
Targeting In-Stent-Stenosis with RGD- and CXCL1-Coated Mini-Stents in Mice.
In: PLOS ONE
11(5), e0155829
[PDF, 846kB]
Hartmann, Petra; Zhou, Zhe; Natarelli, Lucia; Wei, Yuanyuan; Nazari-Jahantigh, Maliheh; Zhu, Mengyu; Grommes, Jochen; Steffens, Sabine; Weber, Christian und Schober, Andreas
(2016):
Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4.
In: Nature Communications, Bd. 7, 10521
[PDF, 2MB]
Chong, Shu Zhen; Evrard, Maximilien; Devi, Sapna; Chen, Jinmiao; Lim, Jyue Yuan; See, Peter; Zhang, Yiru; Adrover, Jose M.; Lee, Bernett; Tan, Leonard; Li, Jackson L. Y.; Liong, Ka Hang; Phua, Cindy; Balachander, Akhila; Boey, Adrian; Liebl, David; Tan, Suet Mien; Chan, Jerry K. Y.; Balabanian, Karl; Harris, John E.; Bianchini, Mariaelvy; Weber, Christian; Duchene, Johan; Lum, Josephine; Poidinger, Michael; Chen, Qingfeng; Renia, Laurent; Wang, Cheng-I; Larbi, Anis; Randolph, Gwendalyn J.; Weninger, Wolfgang; Looney, Mark R.; Krummel, Matthew F.; Biswas, Subhra K.; Ginhoux, Florent; Hidalgo, Andres; Bachelerie, Francoise und Ng, Lai Guan
(2016):
CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses.
In: Journal of Experimental Medicine, Bd. 213, Nr. 11: S. 2293-2314
Rajasekaran, Deepa; Gröning, Sabine; Schmitz, Corinna; Zierow, Swen; Drucker, Natalie; Bakou, Maria; Kohl, Kristian; Mertens, André; Lue, Hongqi; Weber, Christian; Xiao, Annie; Luker, Gary; Kapurniotu, Aphrodite; Lolis, Elias und Bernhagen, Jürgen
(2016):
Macrophage Migration Inhibitory Factor-CXCR4 Receptor Interactions EVIDENCE FOR PARTIAL ALLOSTERIC AGONISM IN COMPARISON WITH CXCL12 CHEMOKINE.
In: Journal of Biological Chemistry, Bd. 291, Nr. 30: S. 15881-15895
Finan, Brian; Clemmensen, Christoffer; Zhu, Zhimeng; Stemmer, Kerstin; Gauthier, Karine; Müller, Luisa; De Angelis, Meri; Moreth, Kristin; Neff, Frauke; Perez-Tilve, Diego; Fischer, Katrin; Lutter, Dominik; Sánchez-Garrido, Miguel A.; Liu, Peng; Tuckermann, Jan; Malehmir, Mohsen; Healy, Marc E.; Weber, Achim; Heikenwalder, Mathias; Jastroch, Martin; Kleinert, Maximilian; Jall, Sigrid; Brandt, Sara; Flamant, Frédéric; Schramm, Karl-Werner; Biebermann, Heike; Doering, Yvonne; Weber, Christian; Habegger, Kirk M.; Keuper, Michaela; Gelfanov, Vasily; Liu, Fa; Köhrle, Josef; Rozman, Jan; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Hofmann, Susanna M.; Yang, Bin; Tschöp, Matthias H.; DiMarchi, Richard und Müller, Timo D.
(2016):
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.
In: Cell, Bd. 167, Nr. 3: S. 843-857
Schmohl, Joerg; Santovito, Donato; Guenther, Thomas; Sutanto, Wishnu; Kroell, Tanja; Salih, Helmut; Pitsch, Thomas; Egea, Virginia; Weber, Christian; Schmetzer, Helga und Ries, Christian
(2016):
Expression of surface-associated 82kDa-proMMP-9 in primary acute leukemia blast cells inversely correlates with patients' risk.
In: Experimental Hematology, Bd. 44, Nr. 5: S. 358-362
Gerdes, Norbert; Seijkens, Tom; Lievens, Dirk; Kuijpers, Marijke J. E.; Winkels, Holger; Projahn, Delia; Hartwig, Helene; Beckers, Linda; Megens, Remco T. A.; Boon, Louis; Noelle, Randolph J.; Soehnlein, Oliver; Heemskerk, Johan W. M.; Weber, Christian und Lutgens, Esther
(2016):
Platelet CD40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 36, Nr. 3: S. 482-490
Meiler, Svenja; Smeets, Esther; Winkels, Holger; Shami, Annelie; Pascutti, Maria Fernanda; Nolte, Martijn A.; Beckers, Linda; Weber, Christian; Gerdes, Norbert und Lutgens, Esther
(2016):
Constitutive GITR Activation Reduces Atherosclerosis by Promoting Regulatory CD4(+) T-Cell ResponsesBrief Report.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 36, Nr. 9: S. 1748-1752
Gamrekelashvili, Jaba; Giagnorio, Roberto; Jussofie, Jasmin; Soehnlein, Oliver; Duchene, Johan; Briseño, Carlos G.; Ramasamy, Saravana K.; Krishnasamy, Kashyap; Limbourg, Anne; Häger, Christine; Kapanadze, Tamar; Ishifune, Chieko; Hinkel, Rabea; Radtke, Freddy; Strobl, Lothar J.; Zimber-Strobl, Ursula; Napp, L. Christian; Bauersachs, Johann; Haller, Hermann; Yasutomo, Koji; Kupatt, Christian; Murphy, Kenneth M.; Adams, Ralf H.; Weber, Christian und Limbourg, Florian P.
(2016):
Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.
In: Nature Communications, Bd. 7, 12597
[PDF, 4MB]
Srikakulapu, Prasad; Hu, Desheng; Yin, Changjun; Mohanta, Sarajo K.; Bontha, Sai Vineela; Peng, Li; Beer, Michael; Weber, Christian; McNamara, Coleen A.; Grassia, Gianluca; Maffia, Pasquale; Manz, Rudolf A. und Habenicht, Andreas J. R.
(2016):
Artery Tertiary Lymphoid Organs Control Multilayered Territorialized Atherosclerosis B-Cell Responses in Aged ApoE(-/-) Mice.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 36, Nr. 6: S. 1174-1185
Li, Jie; McArdle, Sara; Gholami, Amin; Kimura, Takayuki; Wolf, Dennis; Gerhardt, Teresa; Miller, Jacqueline; Weber, Christian und Ley, Klaus
(2016):
CCR5⁺T-bet⁺FoxP3⁺ Effector CD4 T Cells Drive Atherosclerosis.
In: Circulation Research, Bd. 118, Nr. 10:
1540-U213
Viola, Joana R.; Lemnitzer, Patricia; Jansen, Yvonne; Csaba, Gergely; Winter, Carla; Neideck, Carlos; Silvestre-Roig, Carlos; Dittmar, Gunnar; Döring, Yvonne; Drechsler, Maik; Weber, Christian; Zimmer, Ralf; Cenac, Nicolas und Soehnlein, Oliver
(2016):
Resolving Lipid Mediators Maresin 1 and Resolvin D2 Prevent Atheroprogression in Mice.
In: Circulation Research, Bd. 119, Nr. 9: S. 1030-1038
Ortega-Gomez, Almudena; Salvermoser, Melanie; Rossaint, Jan; Pick, Robert; Brauner, Janine; Lemnitzer, Patricia; Tilgner, Jessica; Jong, Renske J. de; Megens, Remco T. A.; Jamasbi, Janina; Döring, Yvonne; Pham, Christine T.; Scheiermann, Christoph; Siess, Wolfgang; Drechsler, Maik; Weber, Christian; Grommes, Jochen; Zarbock, Alexander; Walzog, Barbara und Soehnlein, Oliver
(2016):
Cathepsin G Controls Arterial But Not Venular Myeloid Cell Recruitment.
In: Circulation, Bd. 134, Nr. 16: S. 1176-1188
Agten, Stijn M.; Koenen, Rory R.; Ippel, Hans; Eckardt, Veit; Hundelshausen, Philipp von; Mayo, Kevin H.; Weber, Christian und Hackeng, Tilman M.
(2016):
Probing Functional Heteromeric Chemokine Protein-Protein Interactions through Conformation-Assisted Oxime Ligation.
In: Angewandte Chemie-international Edition, Bd. 55, Nr. 48: S. 14963-14966
Mahl, Christian; Egea, Virginia; Megens, Remco T. A.; Pitsch, Thomas; Santovito, Donato; Weber, Christian und Ries, Christian
(2016):
RECK (reversion-inducing cysteine-rich protein with Kazal motifs) regulates migration, differentiation and Wnt/β -catenin signaling in human mesenchymal stem cells.
In: Cellular and Molecular Life Sciences, Bd. 73, Nr. 7: S. 1489-1501
Deppe, Janina; Popp, Tanja; Egea, Virginia; Steinritz, Dirk; Schmidt, Annette; Thiermann, Horst; Weber, Christian und Ries, Christian
(2016):
Impairment of hypoxia-induced HIF-1 alpha signaling in keratinocytes and fibroblasts by sulfur mustard is counteracted by a selective PHD-2 inhibitor.
In: Archives of Toxicology, Bd. 90, Nr. 5: S. 1141-1150
Tilstam, Pathricia V.; Theelen, Wendy; Alampour-Sarabi, Setareh; Pawig, Lukas; Asare, Yaw; Döring, Yvonne; Winther, Menno P. J. de; Lawrence, Toby; Zernecke, Alma; Bernhagen, Jürgen; Schober, Andreas; Jankowski, Joachim; Weber, Christian und Noels, Heidi
(2016):
Non-activatable mutant of inhibitor of kappa b kinase α (ikk α) exerts site-specific effects on atherosclerosis.
In: Nephrology Dialysis Transplantation, Bd. 31: S. 48
Weber, Christian; Shantsila, Eduard; Hristov, Michael; Caligiuri, Giuseppina; Guzik, Tomasz; Heine, Gunnar H.; Hoefer, Imo E.; Monaco, Claudia; Peter, Karlheinz; Rainger, Ed; Siegbahn, Agneta; Steffens, Sabine; Wojta, Johann und Lip, Gregory Y. H.
(2016):
Role and analysis of monocyte subsets in cardiovascular disease Joint consensus document of the European Society of Cardiology (ESC) Working Groups "Atherosclerosis & Vascular Biology" and "Thrombosis".
In: Thrombosis and Haemostasis, Bd. 116, Nr. 4: S. 626-637
Brastert, Quinte; Silvestre-Roig, Carlos; Hartwigl, Helene; Kusters, Pascal; Aarts, Suzanne; den Toom, Myrthe; Gallo, Richard L.; Weber, Christian; Lutgens, Esther und Soehnlein, Oliver
(2016):
Cathelicidin regulates myeloid cell accumulation in adipose tissue and promotes insulin resistance during obesity.
In: Thrombosis and Haemostasis, Bd. 115, Nr. 6: S. 1237-1239
Mandl, Manuela; Drechsler, Maik; Jansen, Yvonne; Neideck, Carlos; Noels, Heidi; Faussner, Alexander; Soehnlein, Oliver; Weber, Christian und Doering, Yvonne
(2015):
Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation.
In: PLOS ONE
10(8), e0134176
[PDF, 4MB]
Aoqui, Cristiane; Chmielewski, Stefan; Scherer, Elias; Eissler, Ruth; Sollinger, Daniel; Heid, Irina; Braren, Rickmer; Schmaderer, Christoph; Megens, Remco T. A.; Weber, Christian; Heemann, Uwe; Tschöp, Matthias und Baumann, Marcus
(2014):
Microvascular dysfunction in the course of metabolic syndrome induced by high-fat diet.
In: Cardiovascular Diabetology
13:31
[PDF, 3MB]
Blanchet, Xavier; Cesarek, Katja; Brandt, Johanna; Herwald, Heiko; Teupser, Daniel; Küchenhoff, Helmut ORCID: https://orcid.org/0000-0002-6372-2487; Karshovska, Ela; Mause, Sebastian F.; Siess, Wolfgang; Wasmuth, Hermann; Soehnlein, Oliver; Koenen, Rory R.; Weber, Christian und Hundelshausen, Philipp von
(2014):
Inflammatory role and prognostic value of platelet chemokines in acute coronary syndrome.
In: Thrombosis and Haemostasis, Bd. 112, Nr. 6: S. 1277-1287
Hinkel, Rabea; Trenkwalder, Teresa; Petersen, Björn; Husada, Wira; Gesenhues, Florian; Lee, Seungmin; Hannappel, Ewald; Bock-Marquette, Ildiko; Theisen, Daniel; Leitner, Laura; Boekstegers, Peter; Cierniewski, Czeslaw; Müller, Oliver J.; le Noble, Ferdinand; Adams, Ralf H.; Weinl, Christine; Nordheim, Alfred; Reichart, Bruno; Weber, Christian; Olson, Eric; Posern, Guido; Deindl, Elisabeth; Niemann, Heiner und Kupatt, Christian
(2014):
MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2.
In: Nature Communications, Bd. 5, 3970
[PDF, 1MB]
Projahn, Delia; Simsekyilmaz, Sakine; Singh, Smriti; Kanzler, Isabella; Kramp, Birgit K.; Langer, Marcella; Burlacu, Alexandrina; Bernhagen, Jürgen; Klee, Doris; Zernecke, Alma; Hackeng, Tilman M.; Groll, Jürgen; Weber, Christian; Liehn, Elisa A. und Koenen, Rory R.
(2014):
Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction.
In: Journal of Cellular and Molecular Medicine, Bd. 18, Nr. 5: S. 790-800
[PDF, 633kB]
Tilstam, Pathricia V.; Gijbels, Marion J.; Habbeddine, Mohamed; Cudejko, Céline; Asare, Yaw; Theelen, Wendy; Zhou, Baixue; Döring, Yvonne; Drechsler, Maik; Pawig, Lukas; Simsekyilmaz, Sakine; Koenen, Rory R.; de Winther, Menno P. J.; Lawrence, Toby; Bernhagen, Jürgen; Zernecke, Alma; Weber, Christian und Noels, Heidi
(2014):
Bone Marrow-Specific Knock-In of a Non-Activatable Ikk alpha Kinase Mutant Influences Haematopoiesis but Not Atherosclerosis in Apoe-Deficient Mice.
In: PLOS ONE
9(2), e87452
[PDF, 1MB]
Grommes, Jochen; Vijayan, Santosh; Drechsler, Maik; Hartwig, Helene; Mörgelin, Matthias; Dembinski, Rolf; Jacobs, Michael; Koeppel, Thomas Andreas; Binnebösel, Marcel; Weber, Christian und Soehnlein, Oliver
(2012):
Simvastatin reduces endotoxin-induced acute lung injury by decreasing neutrophil recruitment and radical formation.
In: PLOS ONE
7(6), e38917
[PDF, 1MB]
Redondo, Santiago; Gonzalez-Rocafort, Alvaro; Navarro-Dorado, Jorge; Ramajo, Marta; Hristov, Mihail; Gordillo-Moscoso, Antonio; Reguillo, Fernando; Carnero, Manuel; Martinez-Gonzalez, Jose; Rodriguez, Enrique; Weber, Christian und Tejerina, Teresa
(2012):
Decreased pre-surgical CD34(+)/CD144(+) cell number in patients undergoing coronary artery bypass grafting compared to coronary artery disease-free valvular patients.
In: Journal of Cardiothoracic Surgery
7:2
[PDF, 2MB]
Blanchet, Xavier; Langer, Marcella; Weber, Christian; Koenen, Rory R. und Hundelshausen, Philipp von
(2012):
Touch of chemokines.
In: Frontiers in Immunology, Bd. 3, 175
[PDF, 680kB]
Kupatt, Christian; Habazettl, Helmut; Zahler, Stefan; Weber, Christian; Becker, Bernhard F.; Messmer, Konrad und Gerlach, Eckehart
(1997):
ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury.
In: Cardiovascular Research, Bd. 36, Nr. 3: S. 386-395
[PDF, 2MB]
Buchbeitrag
Zhang, Xi; Wang, Zhihua; Zhang, Chuankai; Li, Yutao; Lu, Shu; Steffens, Sabine; Mohanta, Sarajo; Weber, Christian; Habenicht, Andreas und Yin, Changjun
(2022):
Laser Capture Microdissection–Based mRNA Expression Microarrays and Single-Cell RNA Sequencing in Atherosclerosis Research.
In: Ramji, Dipak (Hrsg.):
Atherosclerosis. Methods and protocols. Methods in Molecular Biology, Bd. 2419. New York: Springer US. S. 715-726
Wang, Zhihua; Zhang, Xi; Zhang, Chuankai; Li, Yutao; Lu, Shu; Mohanta, Sarajo; Weber, Christian ORCID: https://orcid.org/0000-0003-4610-8714; Habenicht, Andreas und Yin, Changjun
(2022):
Combined Single-Cell RNA and Single-Cell α/β T Cell Receptor Sequencing of the Arterial Wall in Atherosclerosis.
In: Ramji, Dipak (Hrsg.):
Atherosclerosis. Methods and Protocols. Methods in Molecular Biology, Bd. 2419. New York: Springer US. S. 727-746
Sun, Ting; Li, Yuanfang; Förstera, Benjamin; Stanic, Karen; Lu, Shu; Steffens, Sabine; Yin, Changjun; Ertürk, Ali; Megens, Remco T. A.; Weber, Christian ORCID: https://orcid.org/0000-0003-4610-8714; Habenicht, Andreas und Mohanta, Sarajo K.
(2022):
Tissue Clearing Approaches in Atherosclerosis.
In:
Atherosclerosis. Methods and protocols. Methods in Molecular Biology, Bd. 2419. New York: Humana Press. S. 747-763
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