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Springe zu: Zeitschriftenartikel
Anzahl der Publikationen: 23
Zeitschriftenartikel
Steiner, Philip; Arlt, Elisabeth; Boekhoff, Ingrid; Gudermann, Thomas und Zierler, Susanna
(2022):
Two-Pore Channels Regulate Inter-Organellar Ca2+ Homeostasis in Immune Cells.
In: Cells, Bd. 11, Nr. 9, 1465
Rossig, Anna; Hill, Kerstin; Noerenberg, Wolfgang; Weidenbach, Sebastian; Zierler, Susanna; Schaefer, Michael; Gudermann, Thomas und Chubanov, Vladimir
(2022):
Pharmacological agents selectively acting on the channel moieties of TRPM6 and TRPM7.
In: Cell Calcium, Bd. 106, 102640
Hollenhorst, Monika I.; Nandigama, Rajender; Evers, Saskia B.; Gamayun, Igor; Wadood, Noran Abdel; Salah, Alaa; Pieper, Mario; Wyatt, Amanda; Stukalov, Alexey; Gebhardt, Anna; Nadolni, Wiebke; Burow, Wera; Herr, Christian; Beisswenger, Christoph; Kusumakshi, Soumya; Ectors, Fabien; Kichko, Tatjana I.; Huebner, Lisa; Reeh, Peter; Munder, Antje; Wienhold, Sandra-Maria; Witzenrath, Martin; Bals, Robert; Flockerzi, Veit; Gudermann, Thomas; Bischoff, Markus; Lipp, Peter; Zierler, Susanna; Chubanov, Vladimir; Pichlmair, Andreas; Koenig, Peter; Boehm, Ulrich und Krasteva-Christ, Gabriela
(2022):
Bitter taste signaling in tracheal epithelial brush cells elicits innate immune responses to bacterial infection.
In: Journal of Clinical Investigation, Bd. 132, Nr. 13, e150951
Hoeger, Birgit und Zierler, Susanna
(2022):
Engulf and digest-TRPM7 as key regulator of macrophage phagosome maturation.
In: Cell Calcium, Bd. 106, 102636
Zeitlmayr, Sarah; Zierler, Susanna; Staab-Weijnitz, Claudia A.; Dietrich, Alexander; Geiger, Fabienne; Horgen, F. David; Gudermann, Thomas und Breit, Andreas
(2022):
TRPM7 restrains plasmin activity and promotes transforming growth factor-beta 1 signaling in primary human lung fibroblasts.
In: Archives of Toxicology, Bd. 96, Nr. 10: S. 2767-2783
[PDF, 1MB]
Schmidt, Eva; Narangoda, Chamali; Nörenberg, Wolfgang; Egawa, Miyuki; Rössig, Anna; Leonhardt, Marion; Schäfer, Michael; Zierler, Susanna; Kurnikova, Maria G.; Gudermann, Thomas und Chubanov, Vladimir 
ORCID: https://orcid.org/0000-0002-6042-4193
(2022):
Structural mechanism of TRPM7 channel regulation by intracellular magnesium.
In: Cellular and Molecular Life Sciences, Bd. 79, Nr. 5
[PDF, 4MB]
ORCID: https://orcid.org/0000-0002-6042-4193
(2022):
Structural mechanism of TRPM7 channel regulation by intracellular magnesium.
In: Cellular and Molecular Life Sciences, Bd. 79, Nr. 5
[PDF, 4MB]
Spix, Barbara; Butz, Elisabeth S.; Chen, Cheng-Chang; Rosato, Anna Scotto; Tang, Rachel; Jeridi, Aicha; Kudrina, Veronika; Plesch, Eva; Wartenberg, Philipp; Arlt, Elisabeth; Briukhovetska, Daria; Ansari, Meshal; Günsel, Gizem Günes; Conlon, Thomas M.; Wyatt, Amanda; Wetzel, Sandra; Teupser, Daniel; Holdt, Lesca M.; Ectors, Fabien; Boekhoff, Ingrid; Boehm, Ulrich; García-Añoveros, Jaime; Saftig, Paul; Giera, Martin; Kobold, Sebastian; Schiller, Herbert B.; Zierler, Susanna; Gudermann, Thomas; Wahl-Schott, Christian; Bracher, Franz; Yildirim, Ali Önder; Biel, Martin und Grimm, Christian
(2022):
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice.
In: Nature Communications, Bd. 13, 318
[PDF, 3MB]
Nadolni, Wiebke; Immler, Roland; Hoelting, Kilian; Fraticelli, Marco; Ripphahn, Myriam; Rothmiller, Simone; Matsushita, Masayuki; Boekhoff, Ingrid; Gudermann, Thomas; Sperandio, Markus und Zierler, Susanna
(15. Februar 2021):
TRPM7 Kinase Is Essential for Neutrophil Recruitment and Function via Regulation of Akt/mTOR Signaling.
In: Frontiers in Immunology, Bd. 11, 606893
[PDF, 3MB]
Kollewe, Astrid; Chubanov, Vladimir; Tseung, Fong Tsuen; Correia, Leonor; Schmidt, Eva; Roessig, Anna; Zierler, Susanna; Haupt, Alexander; Mueller, Catrin Swantje; Bildl, Wolfgang; Schulte, Uwe; Nicke, Annette; Fakler, Bernd und Gudermann, Thomas
(2021):
The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics.
In: eLife, Bd. 10, e68544
[PDF, 2MB]
Immler, Roland; Nadolni, Wiebke; Bertsch, Annika; Morikis, Vasilios; Rohwedder, Ina; Masgrau-Alsina, Sergi; Schroll, Tobias; Yevtushenko, Anna; Soehnlein, Oliver; Moser, Markus; Gudermann, Thomas; Barnea, Eytan R.; Rehberg, Markus; Simon, Scott I.; Zierler, Susanna; Pruenster, Monika und Sperandio, Markus
(2021):
The voltage-gated potassium channel K(V)1.3 regulates neutrophil recruitment during inflammation.
In: Cardiovascular Research, Bd. 118, Nr. 5: S. 1289-1302
Arlt, Elisabeth; Fraticelli, Marco; Tsvilovskyy, Volodymyr; Nadolni, Wiebke; Breit, Andreas; O'Neill, Thomas J.; Resenberger, Stefanie; Wennemuth, Gunther; Wahl-Schott, Christian; Biel, Martin; Grimm, Christian; Freichel, Marc; Gudermann, Thomas; Klugbauer, Norbert; Boekhoff, Ingrid und Zierler, Susanna
(2020):
TPC1 deficiency or blockade augments systemic anaphylaxis and mast cell activity.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 117, Nr. 30: S. 18068-18078
Gerndt, Susanne; Chen, Cheng-Chang; Chao, Yu-Kai; Yuan, Yu; Burgstaller, Sandra; Rosato, Anna Scotto; Krogsaeter, Einar; Urban, Nicole; Jacob, Katharina; Ong, Nam Phuong Nguyen; Miller, Meghan T.; Keller, Marco; Vollmar, Angelika M.; Gudermann, Thomas; Zierler, Susanna; Schredelseker, Johann; Schaefer, Michael; Biel, Martin; Malli, Roland; Wahl-Schott, Christian; Bracher, Franz; Patel, Sandip und Grimm, Christian
(2020):
Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function.
In: eLife, Bd. 9, e54712
[PDF, 4MB]
Voringer, Sandra; Schreyer, Laura; Nadolni, Wiebke; Meier, Melanie A.; Woerther, Katharina; Mittermeier, Constanze; Ferioli, Silvia; Singer, Stephan; Holzer, Kerstin; Zierler, Susanna; Chubanov, Vladimir; Liebl, Bernhard; Gudermann, Thomas und Muehlich, Susanne
(2020):
Inhibition of TRPM7 blocks MRTF/SRF-dependent transcriptional and tumorigenic activity.
In: Oncogene, Bd. 39, Nr. 11: S. 2328-2344
Nadolni, Wiebke und Zierler, Susanna
(2018):
The Channel-Kinase TRPM7 as Novel Regulator of Immune System Homeostasis.
In: Cells, Bd. 7, Nr. 8, 109
[PDF, 2MB]
Gotru, Sanjeev K.; Chen, Wenchun; Kraft, Peter; Becker, Isabelle C.; Wolf, Karen; Stritt, Simon; Zierler, Susanna; Hermanns, Heike M.; Rao, Deviyani; Perraud, Anne-Laure; Schmitz, Carsten; Zahedi, Rene P.; Noy, Peter J.; Tomlinson, Michael G.; Dandekar, Thomas; Matsushita, Masayuki; Chubanov, Vladimir; Gudermann, Thomas; Stoll, Guido; Nieswandt, Bernhard und Braun, Attila
(2018):
TRPM7 Kinase Controls Calcium Responses in Arterial Thrombosis and Stroke in Mice.
In: Arteriosclerosis Thrombosis and Vascular Biology, Bd. 38, Nr. 2: S. 344-352
[PDF, 812kB]
Ferioli, Silvia; Zierler, Susanna; Zaisserer, Joanna; Schredelseker, Johann; Gudermann, Thomas und Chubanov, Vladimir
(2017):
TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg2+ and Mg center dot ATP.
In: Scientific Reports, Bd. 7, 8806
[PDF, 3MB]
Zierler, Susanna; Hampe, Sarah und Nadolni, Wiebke
(2017):
TRPM channels as potential therapeutic targets against pro-inflammatory diseases.
In: Cell Calcium, Bd. 67: S. 105-115
Romagnani, Andrea; Vettore, Valentina; Rezzonico-Jost, Tanja; Hampe, Sarah; Rottoli, Elsa; Nadolni, Wiebke; Perotti, Michela; Meier, Melanie A.; Hermanns, Constanze; Geiger, Sheila; Wennemuth, Gunther; Recordati, Camilla; Matsushita, Masayuki; Mühlich, Susanne; Proietti, Michele; Chubanov, Vladimir; Gudermann, Thomas; Grassi, Fabio und Zierler, Susanna
(2017):
TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut.
In: Nature Communications, Bd. 8, 1917
[PDF, 2MB]
Chubanov, Vladimir; Ferioli, Silvia; Wisnowsky, Annika; Simmons, David G.; Leitzinger, Christin; Einer, Claudia; Jonas, Wenke; Shymkiv, Yuriy; Bartsch, Harald; Braun, Attila; Akdogan, Banu; Mittermeier, Lorenz; Sytik, Ludmila; Torben, Friedrich; Jurinovic, Vindi; Vorst, Emiel P. C. van der; Weber, Christian; Yildirim, Önder A.; Sotlar, Karl; Schürmann, Annette; Zierler, Susanna; Zischka, Hans; Ryazanov, Alexey G. und Gudermann, Thomas
(2016):
Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival.
In: eLife, Bd. 5, e20914
[PDF, 3MB]
Schäfer, Sebastian; Ferioli, Silvia; Hofmann, Thomas; Zierler, Susanna; Gudermann, Thomas und Chubanov, Vladimir
(2016):
Mibefradil represents a new class of benzimidazole TRPM7 channel agonists.
In: Pflugers Archiv-European Journal of Physiology, Bd. 468, Nr. 4: S. 623-634
Borth, Heike; Weber, Nele; Meyer, Dorke; Wartenberg, Andrea; Arlt, Elisabeth; Zierler, Susanna; Breit, Andreas; Wennemuth, Gunther; Gudermann, Thomas und Boekhoff, Ingrid
(2016):
The IP3R Binding Protein Released With Inositol 1,4,5-Trisphosphate Is Expressed in Rodent Reproductive Tissue and Spermatozoa.
In: Journal of Cellular Physiology, Bd. 231, Nr. 5: S. 1114-1129
Zierler, Susanna; Sumoza-Toledo, Adriana; Suzuki, Sayuri; Dúill, Fionán Ó.; Ryazanova, Lillia V.; Penner, Reinhold; Ryazanov, Alexey G. und Fleig, Andrea
(2016):
TRPM7 kinase activity regulates murine mast cell degranulation.
In: Journal of Physiology, Bd. 594, Nr. 11: S. 2957-2970
Stritt, Simon; Nurden, Paquita; Favier, Remi; Favier, Marie; Ferioli, Silvia; Gotru, Sanjeev K.; Eeuwijk, Judith M. M. van; Schulze, Harald; Nurden, Alan T.; Lambert, Michele P.; Turro, Ernest; Burger-Stritt, Stephanie; Matsushita, Masayuki; Mittermeier, Lorenz; Ballerini, Paola; Zierler, Susanna; Laffan, Michael A.; Chubanov, Vladimir; Gudermann, Thomas; Nieswandt, Bernhard und Braun, Attila
(2016):
Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg2+ homeostasis and cytoskeletal architecture.
In: Nature Communications, Bd. 7, 11097
[PDF, 4MB]