Lower-Resolution Retrieval of Scenes in Older Adults With Subjective Cognitive Decline

Ruiz-Rizzo, Adriana L. ; Pruitt, Patrick J.; Finke, Kathrin ; Müller, Hermann J. und Damoiseaux, Jessica S. (1. März 2022): Lower-Resolution Retrieval of Scenes in Older Adults With Subjective Cognitive Decline. In: Archives of Clinical Neuropsychology, Bd. 37, Nr. 2: S. 408-422

Abstract

Objective Scenes with more perceptual detail can help detect subtle memory deficits more than scenes with less detail. Here, we investigated whether older adults with subjective cognitive decline (SCD) show less brain activation and more memory deficits to scenes with more (vs. scenes with less) perceptual detail compared to controls (CON).

Method In 37 healthy older adults (SCD: 16), we measured blood oxygenation level-dependent-functional magnetic resonance imaging during encoding and behavioral performance during retrieval.

Results During encoding, higher activation to scenes with more (vs. less) perceptual detail in the parahippocampal place area predicted better memory performance in SCD and CON. During retrieval, superior performance for new scenes with more (vs. less) perceptual detail was significantly more pronounced in CON than in SCD.

Conclusions Together, these results suggest a present, but attenuated benefit from perceptual detail for memory retrieval in SCD. Memory complaints in SCD might, thus, refer to a decreased availability of perceptual detail of previously encoded stimuli.

• Dokumententyp: Zeitschriftenartikel
• EU Funded Grant Agreement Number: 754388
• EU-Projekte: Horizon 2020 > Marie Skłodowska Curie Actions > Marie Skłodowska-Curie: Sonstige Programme > 754388: The LMU Research Fellowship Program: Promoting excellent early-stage postdoctoral researchers at LMU Munich
• Publikationsform: Publisher's Version
• Keywords: Memory encoding, Memory retrieval, Older adults, Parahippocampal place area, Scene complexity, Subjective cognitive decline
• Fakultät: Psychologie und Pädagogik > Department Psychologie > Allgemeine und Experimentelle Psychologie
• Themengebiete: 100 Philosophie und Psychologie > 150 Psychologie ; 500 Naturwissenschaften und Mathematik > 500 Naturwissenschaften
• Sprache: Englisch