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Anzahl der Publikationen: 43
Zeitschriftenartikel
Brech, Dorothee; Herbstritt, Anna S.; Diederich, Sarah; Straub, Tobias; Kokolakis, Evangelos; Irmler, Martin; Beckers, Johannes; Buettner, Florian A.; Schaeffeler, Elke; Winter, Stefan; Schwab, Matthias; Nelson, Peter J. und Noessner, Elfriede
(2022):
Dendritic Cells or Macrophages? The Microenvironment of Human Clear Cell Renal Cell Carcinoma Imprints a Mosaic Myeloid Subtype Associated with Patient Survival.
In: Cells, Bd. 11, Nr. 20, 3289
Sanchez-Gonzalez, Rosario; Koupourtidou, Christina; Lepko, Tjasa; Zambusi, Alessandro; Novoselc, Klara Tereza; Durovic, Tamara; Aschenbroich, Sven; Schwarz, Veronika; Breunig, Christopher T.; Straka, Hans; Huttner, Hagen B.; Irmler, Martin; Beckers, Johannes; Wurst, Wolfgang; Zwergal, Andreas; Schauer, Tamas; Straub, Tobias; Czopka, Tim; Trümbach, Dietrich; Götz, Magdalena; Stricker, Stefan H. und Ninkovic, Jovica
(2022):
Innate Immune Pathways Promote Oligodendrocyte Progenitor Cell Recruitment to the Injury Site in Adult Zebrafish Brain.
In: Cells, Bd. 11, Nr. 3, 520
[PDF, 9MB]
Trefzer, Anne; Kadam, Pallavi; Wang, Shu-Hung; Pennavaria, Stefanie; Lober, Benedikt; Akcabozan, Batuhan; Kranich, Jan; Brocker, Thomas; Nakano, Naoko; Irmler, Martin; Beckers, Johannes; Straub, Tobias und Obst, Reinhard
(2021):
Dynamic adoption of anergy by antigen-exhausted CD4(+) T cells.
In: Cell Reports, Bd. 34, Nr. 6, 108748
Giroud, Maude; Tsokanos, Foivos-Filippos; Caratti, Giorgio; Kotschi, Stefan; Khani, Sajjad; Jouffe, Celine; Vogl, Elena S.; Irmler, Martin; Glantschnig, Christina; Gil-Lozano, Manuel; Hass, Daniela; Khan, Asrar Ali; Garcia, Marcos Rios; Mattijssen, Frits; Maida, Adriano; Tews, Daniel; Fischer-Posovszky, Pamela; Feuchtinger, Annette; Virtanen, Kirsi A.; Beckers, Johannes; Wabitsch, Martin; Uhlenhaut, Henriette; Bluher, Matthias; Tuckermann, Jan; Scheideler, Marcel; Bartelt, Alexander und Herzig, Stephan
(2021):
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.
In: Diabetologia, Bd. 64, Nr. 8: S. 1850-1865
Gerckens, Michael; Schorpp, Kenji; Pelizza, Francesco; Woegrath, Melanie; Reichau, Kora; Ma, Huilong; Dworsky, Armando-Marco; Sengupta, Arunima; Stoleriu, Mircea Gabriel; Heinzelmann, Katharina; Merl-Pham, Juliane; Irmler, Martin; Alsafadi, Hani N.; Trenkenschuh, Eduard; Sarnova, Lenka; Jirouskova, Marketa; Friess, Wolfgang; Hauck, Stefanie M.; Beckers, Johannes; Kneidinger, Nikolaus; Behr, Jürgen; Hilgendorff, Anne; Hadian, Kamyar; Lindner, Michael; Koenigshoff, Melanie; Eickelberg, Oliver; Gregor, Martin; Plettenburg, Oliver; Yildirim, Ali Oender und Burgstaller, Gerald
(2021):
Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics.
In: Science Advances, Bd. 7, Nr. 52, eabb3673
Dreher, Simon I.; Hoeckele, Selina; Huypens, Peter; Irmler, Martin; Hoffmann, Christoph; Jeske, Tim; Hastreiter, Maximilian; Moller, Anja; Birkenfeld, Andreas L.; Haering, Hans-Ulrich; Peter, Andreas; Beckers, Johannes; Hrabe de Angelis, Martin und Weigert, Cora
(2021):
TGF-beta Induction of miR-143/145 Is Associated to Exercise Response by Influencing Differentiation and Insulin Signaling Molecules in Human Skeletal Muscle.
In: Cells, Bd. 10, Nr. 12, 3443
Boettcher, Anika; Buettner, Maren; Tritschler, Sophie; Sterr, Michael; Aliluev, Alexandra; Oppenlaender, Lena; Burtscher, Ingo; Sass, Steffen; Irmler, Martin; Beckers, Johannes; Ziegenhain, Christoph; Enard, Wolfgang; Schamberger, Andrea C.; Verhamme, Fien M.; Eickelberg, Oliver; Theis, Fabian J. und Lickert, Heiko
(2021):
Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.
In: Nature Cell Biology, Bd. 23, Nr. 1
Schriever, Sonja C. 
ORCID: https://orcid.org/0000-0001-5461-3214; Kabra, Dhiraj G.; Pfuhlmann, Katrin; Baumann, Peter ORCID: https://orcid.org/0000-0002-7009-1580; Baumgart, Emily V.; Nagler, Joachim; Seebacher, Fabian ORCID: https://orcid.org/0000-0003-2211-8723; Harrison, Luke; Irmler, Martin ORCID: https://orcid.org/0000-0003-3169-479X; Kullmann, Stephanie; Corrêa-da-Silva, Felipe ORCID: https://orcid.org/0000-0002-7333-367X; Giesert, Florian; Jain, Ruchi; Schug, Hannah; Castel, Julien; Martinez, Sarah; Wu, Moya; Häring, Hans-Ulrich; de Angelis, Martin Hrabe ORCID: https://orcid.org/0000-0002-7898-2353; Beckers, Johannes ORCID: https://orcid.org/0000-0001-7874-3822; Müller, Timo D. ORCID: https://orcid.org/0000-0002-0624-9339; Stemmer, Kerstin; Wurst, Wolfgang; Rozman, Jan ORCID: https://orcid.org/0000-0002-8035-8904; Nogueiras, Ruben; De Angelis, Meri; Molkentin, Jeffery D. ORCID: https://orcid.org/0000-0002-3558-6529; Krahmer, Natalie; Yi, Chun-Xia ORCID: https://orcid.org/0000-0003-1184-4615; Schmidt, Mathias V.; Luquet, Serge; Heni, Martin ORCID: https://orcid.org/0000-0002-8462-3832; Tschöp, Matthias H. und Pfluger, Paul T. ORCID: https://orcid.org/0000-0002-8118-7588
(2020):
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.
In: Journal of Clinical Investigation, Bd. 130, Nr. 11: S. 6093-6108
ORCID: https://orcid.org/0000-0001-5461-3214; Kabra, Dhiraj G.; Pfuhlmann, Katrin; Baumann, Peter ORCID: https://orcid.org/0000-0002-7009-1580; Baumgart, Emily V.; Nagler, Joachim; Seebacher, Fabian ORCID: https://orcid.org/0000-0003-2211-8723; Harrison, Luke; Irmler, Martin ORCID: https://orcid.org/0000-0003-3169-479X; Kullmann, Stephanie; Corrêa-da-Silva, Felipe ORCID: https://orcid.org/0000-0002-7333-367X; Giesert, Florian; Jain, Ruchi; Schug, Hannah; Castel, Julien; Martinez, Sarah; Wu, Moya; Häring, Hans-Ulrich; de Angelis, Martin Hrabe ORCID: https://orcid.org/0000-0002-7898-2353; Beckers, Johannes ORCID: https://orcid.org/0000-0001-7874-3822; Müller, Timo D. ORCID: https://orcid.org/0000-0002-0624-9339; Stemmer, Kerstin; Wurst, Wolfgang; Rozman, Jan ORCID: https://orcid.org/0000-0002-8035-8904; Nogueiras, Ruben; De Angelis, Meri; Molkentin, Jeffery D. ORCID: https://orcid.org/0000-0002-3558-6529; Krahmer, Natalie; Yi, Chun-Xia ORCID: https://orcid.org/0000-0003-1184-4615; Schmidt, Mathias V.; Luquet, Serge; Heni, Martin ORCID: https://orcid.org/0000-0002-8462-3832; Tschöp, Matthias H. und Pfluger, Paul T. ORCID: https://orcid.org/0000-0002-8118-7588
(2020):
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.
In: Journal of Clinical Investigation, Bd. 130, Nr. 11: S. 6093-6108
Kollmus, Heike; Fuchs, Helmut; Lengger, Christoph; Haselimashhadi, Hamed; Bogue, Molly A.; Ostereicher, Manuela A.; Horsch, Marion; Adler, Thure; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; Beckers, Johannes; Calzada-Wack, Julia; Garrett, Lillian; Hans, Wolfgang; Hoelter, Sabine M.; Klein-Rodewald, Tanja; Maier, Holger; Mayer-Kuckuk, Philipp; Miller, Gregor; Moreth, Kristin; Neff, Frauke; Rathkolb, Birgit; Racz, Ildiko; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Busch, Dirk; Graw, Jochen; Klopstock, Thomas; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Onder; Mason, Jeremy; Torres, Arturo; Balling, Rudi; Mehaan, Terry; Gailus-Durner, Valerie; Schughart, Klaus und de Angelis, Martin Hrabe
(2020):
A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.
In: Mammalian Genome, Bd. 31: S. 30-48
[PDF, 3MB]
Chhabra, Nirav Florian; Amarie, Oana Veronica; Wu, Moya; Amend, Anna-Lena; Rubey, Marina; Gradinger, Daniel; Irmler, Martin; Beckers, Johannes; Rathkolb, Birgit; Wolf, Eckhard; Feuchtinger, Annette; Huypens, Peter; Teperino, Raffaele; Rozman, Jan; Przemeck, Gerhard K. H. und Hrabe de Angelis, Martin
(2020):
PAX6 mutation alters circadian rhythm and beta cell function in mice without affecting glucose tolerance.
In: Communications Biology, Bd. 3, Nr. 1, 628
Sluka, Susanna H. M.; Staempfli, Simon F.; Akhmedov, Alexander; Rodewald, Tanja Klein; Sanz-Moreno, Adrian; Horsch, Marion; Grest, Paula; Rothmeier, Andrea S.; Rathkolb, Birgit; Schrewe, Anja; Beckers, Johannes; Neff, Frauke; Wolf, Eckhard; Camici, Giovanni G.; Fuchs, Helmut; Durner, Valerie Gailus; Hrabe de Angelis, Martin; Luescher, Thomas F.; Ruf, Wolfram und Tanner, Felix C.
(2020):
Murine tissue actor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality.
In: Haematologica, Bd. 105, Nr. 10: S. 2484-2495
Ruschil, Christoph; Gabernet, Gisela; Lepennetier, Gildas; Heumos, Simon; Kaminski, Miriam; Hracsko, Zsuzsanna; Irmler, Martin; Beckers, Johannes; Ziemann, Ulf; Nahnsen, Sven; Owens, Gregory P.; Bennett, Jeffrey L.; Hemmer, Bernhard und Kowarik, Markus C.
(2020):
Specific Induction of Double Negative B Cells During Protective and Pathogenic Immune Responses.
In: Frontiers in Immunology, Bd. 11, 606338
[PDF, 2MB]
Nouri, Parivash; Goetz, Sebastian; Rauser, Benedict; Irmler, Martin; Peng, Changgeng; Truembach, Dietrich; Kempny, Christian; Lechermeier, Carina G.; Bryniok, Agnes; Dlugos, Andrea; Euchner, Ellen; Beckers, Johannes; Brodski, Claude; Kluemper, Claudia; Wurst, Wolfgang und Prakash, Nilima
(2020):
Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling.
In: Frontiers in Cell and Developmental Biology, Bd. 8, 587778
[PDF, 13MB]
Dias, Mariana Castro; Coisne, Caroline; Baden, Pascale; Enzmann, Gaby; Garrett, Lillian; Becker, Lore; Hoelter, Sabine M.; de Angelis, Martin Hrabe; Deutsch, Urban; Engelhardt, Britta; Aguilar-Pimentel, Antonio; Adler, Thure; Busch, Dirk H.; Spielmann, Nadine; Moreth, Kristin; Hans, Wolfgang; Amarie, Oana; Graw, Jochen; Rozman, Jan; Radc, Ildiko; Neff, Frauke; Calzada-Wack, Julia; Rathkolb, Birgit; Wolf, Eckhard; Klopstock, Thomas; Wurst, Wolfgang; Beckers, Johannes; Oestereicher, Manuela; Miller, Gregor; Maier, Holger; Stoeger, Claudia; Leuchtenberger, Stefanie; Gailus-Durner, Valerie und Fuchs, Helmut
(2019):
Claudin-12 is not required for blood-brain barrier tight junction function.
In: Fluids and Barriers of the Cns, Bd. 16, Nr. 1, 30
[PDF, 3MB]
Vetrivel, Sharmilee; Tiso, Natascia; Kuegler, Andrea; Irmler, Martin; Horsch, Marion; Beckers, Johannes; Hladik, Daniela; Giesert, Florian; Gailus-Durner, Valerie; Fuchs, Helmut; Sabrautzki, Sibylle; Angelis, Martin Hrabe de; Graw, Jochen; Adler, Thure; Treise, Irina; Busch, Dirk H.; Aguilar-Pimentel, Antonio; Ollert, Markus; Götz, Alexander; Amarie, Oana; Stoeger, Tobias; Schulz, Holger; Becker, Lore; Klopstock, Thomas; Schrewe, Anja; Spielmann, Nadine; Bekeredjian, Raffi; Garrett, Lillian; Hoelter, Sabine M.; Zimprich, Annemarie; Wurst, Wolfgang; Mayer-Kuckuk, Philipp; Hans, Wolfgang; Rozman, Jan; Klingenspor, Martin; Neff, Frauke; Silva-Buttkus, Patricia da; Calzada-Wack, Julia; Racz, Ildiko; Zimmer, Andreas; Rathkolb, Birgit; Wolf, Eckhard; Prehn, Cornelia; Adamski, Jerzy; Oestereicher, Manuela; Miller, Gregor; Steinkamp, Ralph; Lengger, Christoph; Maier, Holger; Stoeger, Claudia und Leuchtenberger, Stefanie
(2019):
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.
In: Experimental Eye Research, Bd. 188, UNSP 107632
[PDF, 7MB]
Wang, Xianming; Sterr, Michael; Burtscher, Ingo; Böttcher, Anika; Beckenbauer, Julia; Siehler, Johanna; Meitinger, Thomas; Haering, Hans-Ulrich; Staiger, Harald; Cernilogar, Filippo M.; Schotta, Gunnar; Irmler, Martin; Beckers, Johannes; Wright, Christopher V. E.; Bakhti, Mostafa und Lickert, Heiko
(2019):
Point mutations in the PDX1 transactivation domain impair human beta-cell development and function.
In: Molecular Metabolism, Bd. 24: S. 80-97
Jeske, Tim; Huypens, Peter; Stirm, Laura; Hoeckele, Selina; Wurmser, Christine M.; Boehm, Anja; Weigert, Cora; Staiger, Harald; Klein, Christoph; Beckers, Johannes und Hastreiter, Maximilian
(2019):
DEUS: an R package for accurate small RNA profiling based on differential expression of unique sequences.
In: Bioinformatics, Bd. 35, Nr. 22: S. 4834-4836
Wang, Xianming; Sterr, Michael; Burtscher, Ingo; Chen, Shen; Hieronimus, Anja; Machicao, Fausto; Staiger, Harald; Häring, Hans-Ulrich; Lederer, Gabriele; Meitinger, Thomas; Cemilogar, Filippo M.; Schotta, Gunnar; Innler, Martin; Beckers, Johannes; Hrabe de Angelis, Martin; Ray, Michael; Wright, Christopher V. E.; Bakhti, Mostafa und Lickert, Heiko
(2018):
Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.
In: Molecular Metabolism, Bd. 9: S. 57-68
[PDF, 3MB]
Di Giaimo, Rossella; Durovic, Tamara; Barquin, Pablo; Kociaj, Anita; Lepko, Tjasa; Aschenbroich, Sven; Breunig, Christopher T.; Irmler, Martin; Cernilogar, Filippo M.; Schotta, Gunnar; Barbosa, Joana S.; Trümbach, Dietrich; Baumgart, Emily Violette; Neuner, Andrea M.; Beckers, Johannes; Wurst, Wolfgang; Stricker, Stefan H. und Ninkovic, Jovica
(2018):
The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Restorative Neurogenesis.
In: Cell Reports, Bd. 25, Nr. 12: S. 3241-3251
[PDF, 4MB]
Rozman, Jan; Rathkolb, Birgit; Oestereicher, Manuela A.; Schütt, Christine; Ravindranath, Aakash Chavan; Leuchtenberger, Stefanie; Sharma, Sapna; Kistler, Martin; Willershaeuser, Monja; Brommage, Robert; Meehan, Terrence F.; Mason, Jeremy; Haselimashhadi, Hamed; Hough, Tertius; Mallon, Ann-Marie; Wells, Sara; Santos, Luis; Lelliott, Christopher J.; White, Jacqueline K.; Sorg, Tania; Champy, Marie-France; Bower, Lynette R.; Reynolds, Corey L.; Flenniken, Ann M.; Murray, Stephen A.; Nutter, Lauryl M. J.; Svenson, Karen L.; West, David; Tocchini-Valentini, Glauco P.; Beaudet, Arthur L.; Bosch, Fatima; Braun, Robert B.; Dobbie, Michael S.; Gao, Xiang; Herault, Yann; Moshiri, Ala; Moore, Bret A.; Lloyd, K. C. Kent; McKerlie, Colin; Masuya, Hiroshi; Tanaka, Nobuhiko; Flicek, Paul; Parkinson, Helen E.; Sedlacek, Radislav; Seong, Je Kyung; Wang, Chi-Kuang Leo; Moore, Mark; Brown, Steve D.; Tschoep, Matthias H.; Wurst, Wolfgang; Klingenspor, Martin; Wolf, Eckhard; Beckers, Johannes; Machicao, Fausto; Peter, Andreas; Staiger, Harald; Häring, Hans-Ulrich; Grallert, Harald; Campillos, Monica; Maier, Holger; Fuchs, Helmut; Gailus-Durner, Valerie; Werner, Thomas und Hrabe de Angelis, Martin
(2018):
Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
In: Nature Communications, Bd. 9, 288
[PDF, 2MB]
Dehmel, Stefan; Nathan, Petra; Bartel, Sabine; El-Merhie, Natalia; Scherb, Hagen; Milger, Katrin; John-Schuster, Gerrit; Yildirim, Ali Oender; Hylkema, Machteld; Irmler, Martin; Beckers, Johannes; Schaub, Bianca; Eickelberg, Oliver und Krauss-Etschmann, Susanne
(2018):
Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner.
In: Scientific Reports, Bd. 8, 7547
[PDF, 2MB]
Heppt, Markus V.; Wang, Joshua X.; Hristova, Denitsa M.; Wei, Zhi; Li, Ling; Evans, Brianna; Beqiri, Marilda; Zaman, Samir; Zhang, Jie; Irmler, Martin; Berking, Carola; Besch, Robert; Beckers, Johannes; Rauscher, Frank J.; Sturm, Rick A.; Fisher, David E.; Herlyn, Meenhard und Fukunaga-Kalabis, Mizuho
(2018):
MSX1-Induced Neural Crest-Like Reprogramming Promotes Melanoma Progression.
In: Journal of Investigative Dermatology, Bd. 138, Nr. 1: S. 141-149
Kleinert, Maximilian; Clemmensen, Christoffer; Hofmann, Susanna M.; Moore, Mary C.; Renner, Simone; Woods, Stephen C.; Huypens, Peter; Beckers, Johannes; Hrabe de Angelis, Martin; Schürmann, Annette; Bakhti, Mostafa; Klingenspor, Martin; Heiman, Mark; Cherrington, Alan D.; Ristow, Michael; Lickert, Heiko; Wolf, Eckhard; Havel, Peter J.; Müller, Timo D. und Tschoep, Matthias H.
(2018):
Animal models of obesity and diabetes mellitus.
In: Nature Reviews Endocrinology, Bd. 14, Nr. 3: S. 140-162
Fuchs, Helmut; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Cho, Yi-Li; Garrett, Lillian; Hölter, Sabine M.; Irmler, Martin; Kistler, Martin; Kraiger, Markus; Mayer-Kuckuk, Philipp; Moreth, Kristin; Rathkolb, Birgit; Rozman, Jan; Silva Buttkus, Patricia da; Treise, Irina; Zimprich, Annemarie; Gampe, Kristine; Hutterer, Christine; Stoeger, Claudia; Leuchtenberger, Stefanie; Maier, Holger; Miller, Manuel; Scheideler, Angelika; Wu, Moya; Beckers, Johannes; Bekeredjian, Raffi; Brielmeier, Markus; Busch, Dirk H.; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Schmidt-Weber, Carsten; Stoeger, Tobias; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Oender; Zimmer, Andreas; Gailus-Durner, Valerie und Hrabe de Angelis, Martin
(2018):
Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.
In: Behavioural Brain Research, Bd. 352: S. 187-196
Sattler, Christine; Moritz, Franco; Chen, Shanze; Steer, Beatrix; Kutschke, David; Irmler, Martin; Beckers, Johannes; Eickelberg, Oliver; Schmitt-Kopplin, Philippe; Adler, Heiko und Stoeger, Tobias
(2017):
Nanoparticle exposure reactivates latent herpesvirus and restores a signature of acute infection.
In: Particle and Fibre Toxicology
14:2
[PDF, 8MB]
Kaklamanos, Aimilios; Rozman, Jan; Roulis, Manolis; Karagianni, Niki; Armaka, Maria; Wu, Moya; Brachthäuser, Laura; Calzada-Wack, Julia; Horsch, Marion; Beckers, Johannes; Rathkolb, Birgit; Adler, Thure; Neff, Frauke; Wolf, Eckhard; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin und Kollias, George
(2017):
Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression.
In: Scientific Reports, Bd. 7, 2397
[PDF, 6MB]
Kumar, Sudhir; Rathkolb, Birgit; Sabrautzki, Sibylle; Krebs, Stefan; Kemter, Elisabeth; Becker, Lore; Beckers, Johannes; Bekeredjian, Raffi; Brommage, Robert; Calzada-Wack, Julia; Garrett, Lillian; Hölter, Sabine M.; Horsch, Marion; Klingenspor, Martin; Klopstock, Thomas; Moreth, Kristin; Neff, Frauke; Rozman, Jan; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Wolf, Eckhard und Aigner, Bernhard
(2017):
Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1(I27N) mutant mice.
In: Journal of Biomedical Science
24:57
[PDF, 870kB]
Milger, Katrin; Yu, Yingyan; Brudy, Eva; Irmler, Martin; Skapenko, Alla; Mayinger, Michael; Lehmann, Mareike; Beckers, Johannes; Reichenberger, Frank; Behr, Jürgen; Eickelberg, Oliver; Königshoff, Melanie und Krauss-Etschmann, Susanne
(2017):
Pulmonary CCR2(+)CD4(+) T cells are immune regulatory and attenuate lung fibrosis development.
In: Thorax, Bd. 72, Nr. 11: S. 1007-1020
[PDF, 9MB]
Kästle, Marc; Bartel, Sabine; Geillinger-Kästle, Kerstin; Irmler, Martin; Beckers, Johannes; Ryffel, Bernhard; Eickelberg, Oliver und Krauss-Etschmann, Susanne
(2017):
microRNA cluster 106a similar to 363 is involved in T helper 17 cell differentiation.
In: Immunology, Bd. 152, Nr. 3: S. 402-413
Altmae, Signe; Segura, Maria T.; Esteban, Francisco J.; Bartel, Sabine; Brandi, Pilar; Irmler, Martin; Beckers, Johannes; Demmelmair, Hans; Lopez-Sabater, Carmen; Koletzko, Berthold; Krauss-Etschmann, Susanne und Campoy, Cristina
(2017):
Maternal Pre-Pregnancy Obesity Is Associated with Altered Placental Transcriptome.
In: PLOS ONE 12(1), e0169223 [PDF, 2MB]
In: PLOS ONE 12(1), e0169223 [PDF, 2MB]
Franko, Andras; Huypens, Peter; Neschen, Susanne; Irmler, Martin; Rozman, Jan; Rathkolb, Birgit; Neff, Frauke; Prehn, Cornelia; Dubois, Guillaume; Baumann, Martina; Massinger, Rebecca; Gradinger, Daniel; Przemeck, Gerhard K. H.; Repp, Birgit; Aichler, Michaela; Feuchtinger, Annette; Schommers, Philipp; Stöhr, Oliver; Sanchez-Lasheras, Carmen; Adamski, Jerzy; Peter, Andreas; Prokisch, Holger; Beckers, Johannes; Walch, Axel K.; Fuchs, Helmut; Wolf, Eckhard; Schubert, Markus; Wiesner, Rudolf J. und de Angelis, Martin Hrabe
(2016):
Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice.
In: Diabetes, Bd. 65, Nr. 9: S. 2540-2552
Wittmann, Anke; Grimm, Marcus O. W.; Scherthan, Harry; Horsch, Marion; Beckers, Johannes; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Ford, Steven J.; Burton, Neal C.; Razansky, Daniel; Trümbach, Dietrich; Aichler, Michaela; Walch, Axel Karl; Calzada-Wack, Julia; Neff, Frauke; Wurst, Wolfgang; Hartmann, Tobias und Floss, Thomas
(2016):
Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice.
In: PLOS ONE 11(10), e0164298 [PDF, 5MB]
In: PLOS ONE 11(10), e0164298 [PDF, 5MB]
Kumar, Sudhir; Rathkolb, Birgit; Kemter, Elisabeth; Sabrautzki, Sibylle; Michel, Dian; Adler, Thure; Becker, Lore; Beckers, Johannes; Busch, Dirk H.; Garrett, Lillian; Hans, Wolfgang; Hölter, Sabine M.; Horsch, Marion; Klingenspor, Martin; Klopstock, Thomas; Rácz, Ildikó; Rozman, Jan; Panesso, Ingrid Liliana Vargas; Vernaleken, Alexandra; Zimmer, Andreas; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Wolf, Eckhard und Aigner, Bernhard
(2016):
Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3(L423P) Mutant Mice.
In: PLOS ONE 11(3), e0150472 [PDF, 1MB]
In: PLOS ONE 11(3), e0150472 [PDF, 1MB]
Gascón, Sergio; Murenu, Elisa; Masserdotti, Giacomo; Ortega, Felipe; Russo, Gianluca L.; Petrik, David; Deshpande, Aditi; Heinrich, Christophe; Karow, Marisa; Robertson, Stephen P.; Schroeder, Timm; Beckers, Johannes; Irmler, Martin; Berndt, Carsten; Angeli, José P. Friedmann; Conrad, Marcus; Berninger, Benedikt und Götz, Magdalena
(2016):
Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming.
In: Cell Stem Cell, Bd. 18, Nr. 3: S. 396-409
Fuchs, Helmut; Sabrautzki, Sibylle; Przemeck, Gerhard K. H.; Leuchtenberger, Stefanie; Lorenz-Depiereux, Bettina; Becker, Lore; Rathkolb, Birgit; Horsch, Marion; Garrett, Lillian; Östereicher, Manuela A.; Hans, Wolfgang; Abe, Koichiro; Sagawa, Nobuho; Rozman, Jan; Vargas-Panesso, Ingrid L.; Sandholzer, Michael; Lisse, Thomas S.; Adler, Thure; Aguilar-Pimentel, Juan Antonio; Calzada-Wack, Julia; Ehrhard, Nicole; Elvert, Ralf; Gau, Christine; Hölter, Sabine M.; Micklich, Katja; Moreth, Kristin; Prehn, Cornelia; Puk, Oliver; Racz, Ildiko; Stoeger, Claudia; Vernaleken, Alexandra; Michel, Dian; Diener, Susanne; Wieland, Thomas; Adamski, Jerzy; Bekeredjian, Raffi; Busch, Dirk H.; Favor, John; Graw, Jochen; Klingenspor, Martin; Lengger, Christoph; Maier, Holger; Neff, Frauke; Ollert, Markus; Stoeger, Tobias; Yildirim, Ali Önder; Strom, Tim M.; Zimmer, Andreas; Wolf, Eckhard; Wurst, Wolfgang; Klopstock, Thomas; Beckers, Johannes; Gailus-Durner, Valerie und Hrabé de Angelis, Martin
(2016):
The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.
In: G3-Genes Genomes Genetics, Bd. 6, Nr. 12: S. 4035-4046
Eisenberg, Tobias; Abdellatif, Mahmoud; Schroeder, Sabrina; Primessnig, Uwe; Stekovic, Slaven; Pendl, Tobias; Harger, Alexandra; Schipke, Julia; Zimmermann, Andreas; Schmidt, Albrecht; Tong, Mingming; Ruckenstuhl, Christoph; Dammbrueck, Christopher; Gross, Angelina S.; Herbst, Viktoria; Magnes, Christoph; Trausinger, Gert; Narath, Sophie; Meinitzer, Andreas; Hu, Zehan; Kirsch, Alexander; Eller, Kathrin; Carmona-Gutierrez, Didac; Büttner, Sabrina; Pietrocola, Federico; Knittelfelder, Oskar; Schrepfer, Emilie; Rockenfeller, Patrick; Simonini, Corinna; Rahn, Alexandros; Horsch, Marion; Moreth, Kristin; Beckers, Johannes; Fuchs, Helmut; Gailus-Durner, Valerie; Neff, Frauke; Janik, Dirk; Rathkolb, Birgit; Rozman, Jan; Hrabe de Angelis, Martin; Moustafa, Tarek; Haemmerle, Guenter; Mayr, Manuel; Willeit, Peter; Frieling-Salewsky, Marion von; Pieske, Burkert; Scorrano, Luca; Pieber, Thomas; Pechlaner, Raimund; Willeit, Johann; Sigrist, Stephan J.; Linke, Wolfgang A.; Mühlfeld, Christian; Sadoshima, Junichi; Dengjel, Joern; Kiechl, Stefan; Kroemer, Guido; Sedej, Simon und Madeo, Frank
(2016):
Cardioprotection and lifespan extension by the natural polyamine spermidine.
In: Nature Medicine, Bd. 22, Nr. 12: S. 1428-1438
Korner, Germaine; Scherer, Tanja; Adamsen, Dea; Rebuffat, Alexander; Crabtree, Mark; Rassi, Anahita; Scavelli, Rossana; Homma, Daigo; Ledermann, Birgit; Konrad, Daniel; Ichinose, Hiroshi; Wolfrum, Christian; Horsch, Marion; Rathkolb, Birgit; Klingenspor, Martin; Beckers, Johannes; Wolf, Eckhard; Gailus-Durner, Valérie; Fuchs, Helmut; Hrabě de Angelis, Martin; Blau, Nenad; Rozman, Jan und Thöny, Beat
(2016):
Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice.
In: Journal of inherited Metabolic Disease, Bd. 39, Nr. 2: S. 309-319
Schmidt, Johanna M.; Panzilius, Elena; Bartsch, Harald S.; Irmler, Martin; Beckers, Johannes; Kari, Vijayalakshmi; Linnemann, Jelena R.; Dragoi, Diana; Hirschi, Benjamin; Kloos, Uwe J.; Sass, Steffen; Theis, Fabian; Kahlert, Steffen; Johnsen, Steven A.; Sotlar, Karl und Scheel, Christina H.
(2015):
Stem-Cell-like Properties and Epithelial Plasticity Arise as Stable Traits after Transient Twist1 Activation.
In: Cell Reports, Bd. 10, Nr. 2: S. 131-139
[PDF, 3MB]
Oehrle, Bettina; Burgstaller, Gerald; Irmler, Martin; Dehmel, Stefan; Gruen, Jessica; Hwang, Tiffany; Krauss-Etschmann, Susanne; Beckers, Johannes; Meiners, Silke und Eickelberg, Oliver
(2015):
Validated prediction of pro-invasive growth factors using a transcriptome-wide invasion signature derived from a complex 3D invasion assay.
In: Scientific Reports, Bd. 5, 12673
[PDF, 1MB]
Horsch, Marion; Beckers, Johannes; Fuchs, Helmut; Gailus-Durner, Valérie; Hrabě de Angelis, Martin; Rathkolb, Birgit; Wolf, Eckhard; Aigner, Bernhard und Kemter, Elisabeth
(2014):
Uromodulin Retention in Thick Ascending Limb of Henle's Loop Affects SCD1 in Neighboring Proximal Tubule: Renal Transcriptome Studies in Mouse Models of Uromodulin-Associated Kidney Disease.
In: PLOS ONE 9(11), e113125 [PDF, 911kB]
In: PLOS ONE 9(11), e113125 [PDF, 911kB]
Gewies, Andreas; Gorka, Oliver; Bergmann, Hanna; Pechloff, Konstanze; Petermann, Franziska; Jeltsch, Katharina M.; Rudelius, Martina; Kriegsmann, Mark; Weichert, Wilko; Horsch, Marion; Beckers, Johannes; Wurst, Wolfgang; Heikenwalder, Mathias; Korn, Thomas; Heissmeyer, Vigo und Ruland, Jürgen
(2014):
Uncoupling Malt1 Threshold Function from Paracaspase Activity Results in Destructive Autoimmune Inflammation.
In: Cell Reports, Bd. 9, Nr. 4: S. 1292-1305
[PDF, 4MB]
Tocchetti, Arianna; Soppo, Charlotte Blanche Ekalle; Zani, Fabio; Bianchi, Fabrizio; Gagliani, Maria Cristina; Pozzi, Benedetta; Rozman, Jan; Elvert, Ralf; Ehrhardt, Nicole; Rathkolb, Birgit; Moerth, Corinna; Horsch, Marion; Fuchs, Helmut; Gailus-Durner, Valérie; Beckers, Johannes; Klingenspor, Martin; Wolf, Eckhard; Hrabé de Angelis, Martin; Scanziani, Eugenio; Tacchetti, Carlo; Scita, Giorgio; Di Fiore, Pier Paolo und Offenhäuser, Nina
(2010):
Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice.
In: PLOS ONE 5(3), e9468 [PDF, 2MB]
In: PLOS ONE 5(3), e9468 [PDF, 2MB]
Soeker, Torben; Dalke, Claudia; Puk, Oliver; Floss, Thomas; Becker, Lore; Bolle, Ines; Favor, Jack; Hans, Wolfgang; Hoelter, Sabine M.; Horsch, Marion; Kallnik, Magdalena; Kling, Eva; Moerth, Corinna; Schrewe, Anja; Stigloher, Christian; Topp, Stefanie; Gailus-Durner, Valerie; Naton, Beatrix; Beckers, Johannes; Fuchs, Helmut; Ivandic, Boris; Klopstock, Thomas; Schulz, Holger; Wolf, Eckhard; Wurst, Wolfgang; Bally-Cuif, Laure; de Angelis, Martin Hrabe und Graw, Jochen
(2008):
Pleiotropic effects in Eya3 knockout mice.
In: BMC Developmental Biology
8:118
[PDF, 3MB]