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Anzahl der Publikationen: 80

Zeitschriftenartikel

Adorjan, Kristina ORCID logoORCID: https://orcid.org/0000-0001-7501-9556; Dong, Mark Sen; Wratil, Paul R.; Schmacke, Niklas A.; Weinberger, Tobias; Steffen, Julius ORCID logoORCID: https://orcid.org/0000-0002-8807-7365; Osterman, Andreas ORCID logoORCID: https://orcid.org/0000-0001-5435-5972; Choukér, Alexander ORCID logoORCID: https://orcid.org/0000-0002-0133-4104; Mueller, Tonina T. ORCID logoORCID: https://orcid.org/0000-0002-3123-3064; Jebrini, Tarek; Wiegand, Hauke Felix; Tüscher, Oliver; Lieb, Klaus; Hornung, Veit ORCID logoORCID: https://orcid.org/0000-0002-4150-194X; Falkai, Peter ORCID logoORCID: https://orcid.org/0000-0003-2873-8667; Klein, Matthias; Keppler, Oliver T. ORCID logoORCID: https://orcid.org/0000-0002-1384-8946 und Koutsouleris, Nikolaos (2024): Development and Validation of a Simple Tool for Predicting Pandemic-Related Psychological Distress Among Health Care Workers. In: Journal of Technology in Behavioral Science, Bd. 9, Nr. 3: S. 552-566 [PDF, 4MB]

Szymanska, Inga; Bauernfried, Stefan; Komar, Tobias und Hornung, Veit ORCID logoORCID: https://orcid.org/0000-0002-4150-194X (2024): Vaccinia virus F1L blocks the ribotoxic stress response to subvert ZAKα‐dependent NLRP1 inflammasome activation. In: European Journal of Immunology [PDF, 1MB]

Bérouti, Marleen; Lammens, Katja; Heiss, Matthias; Hansbauer, Larissa; Bauernfried, Stefan; Stöckl, Jan; Pinci, Francesca; Piseddu, Ignazio; Greulich, Wilhelm; Wang, Meiyue; Jung, Christophe; Fröhlich, Thomas; Carell, Thomas ORCID logoORCID: https://orcid.org/0000-0001-7898-2831; Hopfner, Karl-Peter ORCID logoORCID: https://orcid.org/0000-0002-4528-8357 und Hornung, Veit ORCID logoORCID: https://orcid.org/0000-0002-4150-194X (2024): Lysosomal endonuclease RNase T2 and PLD exonucleases cooperatively generate RNA ligands for TLR7 activation. In: Immunity, Bd. 57, Nr. 7: S. 1482-1496 [PDF, 5MB]

Koletzko, Sibylle; Le Thi, Thu Giang; Zhelyazkova, Ana; Osterman, Andreas; Wichert, Sven P.; Breiteneicher, Simone; Koletzko, Leandra; Schwerd, Tobias; Völk, Stefanie; Jebrini, Tarek; Horak, Jeannie; Tuschen, Marina; Choukér, Alexander ORCID logoORCID: https://orcid.org/0000-0002-0133-4104; Hornung, Veit ORCID logoORCID: https://orcid.org/0000-0002-4150-194X; Keppler, Oliver T. ORCID logoORCID: https://orcid.org/0000-0002-1384-8946; Koletzko, Berthold ORCID logoORCID: https://orcid.org/0000-0002-5345-7165; Török, Helga P.; Adorjan, Kristina ORCID logoORCID: https://orcid.org/0000-0001-7501-9556; Garcia, I. Badell; Huber, M.; Wratil, P. R.; Gryaznova, A.; Jebrini, T.; Kohl, P.; De Jonge, S.; Matzel, S.; Hörl, M.; Moser, M.; Rech, J.; Ludwig, C.; Hansbauer, L.; Zhelyazkova, A.; Klein, M.; Völk, S.; Kim-Helmuth, S.; Puzek, B. und Kastenmüller, G. (2023): A prospective longitudinal cohort study on risk factors for COVID-19 vaccination failure (RisCoin): methods, procedures and characterization of the cohort. In: Clinical and Experimental Medicine, Bd. 23, Nr. 8: S. 4901-4917 [PDF, 1MB]

Kuhl, Niklas ORCID logoORCID: https://orcid.org/0000-0003-4970-4677; Linder, Andreas ORCID logoORCID: https://orcid.org/0000-0002-0623-5105; Philipp, Nora ORCID logoORCID: https://orcid.org/0000-0002-3918-7795; Nixdorf, Daniel ORCID logoORCID: https://orcid.org/0000-0003-1612-9952; Fischer, Hannah ORCID logoORCID: https://orcid.org/0000-0003-0540-1930; Veth, Simon; Kuut, Gunnar; Xu, Teng Teng ORCID logoORCID: https://orcid.org/0000-0001-9129-913X; Theurich, Sebastian ORCID logoORCID: https://orcid.org/0000-0001-5706-8258; Carell, Thomas; Subklewe, Marion ORCID logoORCID: https://orcid.org/0000-0001-9154-9469 und Hornung, Veit ORCID logoORCID: https://orcid.org/0000-0002-4150-194X (2023): STING agonism turns human T cells into interferon‐producing cells but impedes their functionality. In: EMBO reports, Bd. 24, Nr. 3 [PDF, 1MB]

Pinci, Francesca; Gaidt, Moritz M.; Jung, Christophe; Nagl, Dennis; Kuut, Gunnar und Hornung, Veit (12. Dezember 2022): Tumor necrosis factor is a necroptosis-associated alarmin. In: Frontiers in Immunology, Bd. 13 [PDF, 7MB]

Wratil, Paul R.; Stern, Marcel; Priller, Alina; Willmann, Annika; Almanzar, Giovanni; Vogel, Emanuel; Feuerherd, Martin; Cheng, Cho-Chin; Yazici, Sarah; Christa, Catharina; Jeske, Samuel; Lupoli, Gaia; Vogt, Tim; Albanese, Manuel; Mejias-Perez, Ernesto; Bauernfried, Stefan; Graf, Natalia; Mijocevic, Hrvoje; Vu, Martin; Tinnefeld, Kathrin; Wettengel, Jochen; Hoffmann, Dieter; Muenchhoff, Maximilian; Daechert, Christopher; Mairhofer, Helga; Krebs, Stefan; Fingerle, Volker; Graf, Alexander; Steininger, Philipp; Blum, Helmut; Hornung, Veit; Liebl, Bernhard; Ueberla, Klaus; Prelog, Martina; Knolle, Percy; Keppler, Oliver T. und Protzer, Ulrike (2022): Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern. In: Nature Medicine, Bd. 28, Nr. 3: S. 496-503

Stafford, Che A.; Gassauer, Alicia-Marie; Oliveira Mann, Carina C. de; Tanzer, Maria C. ORCID logoORCID: https://orcid.org/0000-0002-4657-9869; Fessler, Evelyn; Wefers, Benedikt ORCID logoORCID: https://orcid.org/0000-0002-2492-9389; Nagl, Dennis; Kuut, Gunnar; Sulek, Karolina; Vasilopoulou, Catherine; Schwojer, Sophia J. ORCID logoORCID: https://orcid.org/0000-0002-1747-4144; Wiest, Andreas ORCID logoORCID: https://orcid.org/0000-0003-2525-6304; Pfautsch, Marie K.; Wurst, Wolfgang ORCID logoORCID: https://orcid.org/0000-0003-4422-7410; Yabal, Monica ORCID logoORCID: https://orcid.org/0000-0003-3495-7671; Fröhlich, Thomas ORCID logoORCID: https://orcid.org/0000-0002-4709-3211; Mann, Matthias ORCID logoORCID: https://orcid.org/0000-0003-1292-4799; Gisch, Nicolas ORCID logoORCID: https://orcid.org/0000-0003-3260-5269; Jae, Lucas T. ORCID logoORCID: https://orcid.org/0000-0002-3531-1760 und Hornung, Veit ORCID logoORCID: https://orcid.org/0000-0002-4150-194X (2022): Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation. In: Nature, Bd. 609: S. 590-596 [PDF, 10MB]

Bauer, Amelie; Puglisi, Matteo; Nagl, Dennis; Schick, Joel A.; Werner, Thomas; Klingl, Andreas; El Andari, Jihad; Hornung, Veit ORCID logoORCID: https://orcid.org/0000-0002-4150-194X; Kessler, Horst; Götz, Magdalena ORCID logoORCID: https://orcid.org/0000-0003-1551-9203; Grimm, Dirk und Brack‐Werner, Ruth ORCID logoORCID: https://orcid.org/0000-0002-8651-9318 (2022): Molecular Signature of Astrocytes for Gene Delivery by the Synthetic Adeno‐Associated Viral Vector rAAV9P1. In: Advanced Science, Bd. 9, Nr. 16, 2104979 [PDF, 3MB]

Stazzoni, Samuele; Böhmer, Daniel F. R.; Hernichel, Fabian; Özdemir, Dilara; Pappa, Aikaterini; Drexler, David; Bauernfried, Stefan; Witte, Gregor; Wagner, Mirko; Veth, Simon; Hopfner, Karl-Peter; Hornung, Veit; König, Lars M. und Carell, Thomas (2022): Novel Poxin Stable cGAMP-Derivatives Are Remarkable STING Agonists. In: Angewandte Chemie International Edition, Bd. 61, Nr. 40 [PDF, 2MB]

Robinson, Kim S.; Toh, Gee Ann; Rozario, Pritisha; Chua, Rae; Bauernfried, Stefan; Sun, Zijin; Firdaus, Muhammad Jasrie; Bayat, Shima; Nadkarni, Rhea; Poh, Zhi Sheng; Tham, Khek Chian; Harapas, Cassandra R.; Lim, Chrissie K.; Chu, Werncui; Tay, Celest W. S.; Tan, Kiat Yi; Zhao, Tianyun; Bonnard, Carine; Sobota, Radoslaw; Connolly, John E.; Common, John; Masters, Seth L.; Chen, Kaiwen W.; Ho, Lena; Wu, Bin; Hornung, Veit und Zhong, Franklin L. (2022): ZAK alpha-driven ribotoxic stress response activates the human NLRP1 inflammasome. In: Science, Bd. 377, Nr. 6603: S. 328-334

Schubert, Nadja; Schumann, Tina; Daum, Elena; Flade, Karolin; Ge, Yan; Hagedorn, Lara; Edelmann, Winfried; Mueller, Luise; Schmitz, Marc; Kuut, Gunnar; Hornung, Veit; Behrendt, Rayk und Roers, Axel (2022): Genome Replication Is Associated With Release of Immunogenic DNA Waste. In: Frontiers in Immunology, Bd. 13, 880413

Mangan, Matthew S. J.; Gorki, Friederike; Krause, Karoline; Heinz, Alexander; Pankow, Anne; Ebert, Thomas; Jahn, Dieter; Hiller, Karsten; Hornung, Veit; Maurer, Marcus; Schmidt, Florian I.; Gerhard, Ralf und Latz, Eicke (2022): Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever.
In: PLOS Biology 20(11), e3001351

Armbruster, Julia; Aboouf, Mostafa A.; Gassmann, Max; Egert, Angela; Schorle, Hubert; Hornung, Veit; Schmidt, Tobias; Schmid-Burgk, Jonathan L.; Kristiansen, Glen; Bicker, Anne; Hankeln, Thomas; Zhu, Hao und Gorr, Thomas A. (2022): Myoglobin regulates fatty acid trafficking and lipid metabolism in mammary epithelial cells.
In: PLOS One 17(10), e0275725

Linder, Andreas und Hornung, Veit (2022): Inflammasomes in T cells. In: Journal of Molecular Biology, Bd. 434, Nr. 4, 167275

Schmacke, Niklas A.; O'Duill, Fionan; Gaidt, Moritz M.; Szymanska, Inga; Kamper, Julia M.; Schmid-Burgk, Jonathan L.; Maedler, Sophia C.; Mackens-Kiani, Timur; Kozaki, Tatsuya; Chauhan, Dhruv; Nagl, Dennis; Stafford, Che A.; Harz, Hartmann; Froehlich, Adrian L.; Pinci, Francesca; Ginhoux, Florent; Beckmann, Roland; Mann, Matthias; Leonhardt, Heinrich und Hornung, Veit (2022): IKKO primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network. In: Immunity, Bd. 55, Nr. 12: S. 2271-2284

Oliveira Mann, Carina C. de und Hornung, Veit (2021): Molecular mechanisms of nonself nucleic acid recognition by the innate immune system. In: European Journal of Immunology, Bd. 51, Nr. 8: S. 1897-1910

Wratil, Paul R.; Schmacke, Niklas A.; Osterman, Andreas; Weinberger, Tobias; Rech, Jochen; Karakoc, Burak; Zeilberger, Mira; Steffen, Julius; Mueller, Tonina T.; Spaeth, Patricia M.; Stern, Marcel; Albanese, Manuel; Thun, Hella; Reinbold, Julia; Sandmeyer, Benedikt; Kressirer, Philipp; Grabein, Béatrice; Falkai, Peter; Adorjan, Kristina; Hornung, Veit; Kaderali, Lars; Klein, Matthias und Keppler, Oliver T. (2021): In-depth profiling of COVID-19 risk factors and preventive measures in healthcare workers. In: Infection [PDF, 1MB]

Albanese, Manuel; Ruhle, Adrian; Mittermaier, Jennifer; Mejias-Perez, Ernesto; Gapp, Madeleine; Linder, Andreas; Schmacke, Niklas A.; Hofmann, Katharina; Hennrich, Alexandru A.; Levy, David N.; Humpe, Andreas; Conzelmann, Karl-Klaus; Hornung, Veit; Fackler, Oliver T. und Keppler, Oliver T. (2021): Rapid, efficient and activation-neutral gene editing of polyclonal primary human resting CD4(+) T cells allows complex functional analyses. In: Nature Methods, Bd. 19, Nr. 1: S. 81-89

Altstetter, Sebastian Maximilian; Quitt, Oliver; Pinci, Francesca; Hornung, Veit; Lucko, Aaron Michael; Wisskirchen, Karin; Jung, Stephanie und Protzer, Ulrike (2021): Hepatitis-D Virus Infection Is Not Impaired by Innate Immunity but Increases Cytotoxic T-Cell Activity. In: Cells, Bd. 10, Nr. 11, 3253

Bauernfried, Stefan und Hornung, Veit (2021): DPP9 restrains NLRP1 activation. In: Nature Structural & Molecular Biology, Bd. 28, Nr. 4: S. 333-336

Bauernfried, Stefan; Scherr, Matthias J.; Pichlmair, Andreas; Duderstadt, Karl E. und Hornung, Veit (2021): Human NLRP1 is a sensor for double-stranded RNA. In: Science, Bd. 371, Nr. 6528, eabd0811

Brandt, Margot; Kim-Hellmuth, Sarah; Ziosi, Marcello; Gokden, Alper; Wolman, Aaron; Lam, Nora; Recinos, Yocelyn; Daniloski, Zharko; Morris, John A.; Hornung, Veit; Schumacher, Johannes und Lappalainen, Tuuli (2021): An autoimmune disease risk variant: A trans master regulatory effect mediated by IRF1 under immune stimulation?
In: PLOS Genetics 17(7), e1009684

Ghosh, Suvoshree; Kraus, Katrin; Biswas, Arijit; Müller, Jens; Buhl, Anna-Lena; Forin, Francesco; Singer, Heike; Höning, Klara; Hornung, Veit; Watzka, Matthias; Czogalla-Nitsche, Katrin J. und Oldenburg, Johannes (2021): GGCX mutations show different responses to vitamin K thereby determining the severity of the hemorrhagic phenotype in VKCFD1 patients. In: Journal of Thrombosis and Haemostasis, Bd. 19, Nr. 6: S. 1412-1424

Roth, Stefan; Cao, Jiayu; Singh, Vikramjeet; Tiedt, Steffen; Hundeshagen, Gabriel; Li, Ting; Boehme, Julia D.; Chauhan, Dhruv; Zhu, Jie; Ricci, Alessio; Gorka, Oliver; Asare, Yaw; Yang, Jun; Lopez, Mary S.; Rehberg, Markus; Bruder, Dunja; Zhang, Shengxiang; Gross, Olaf; Dichgans, Martin ORCID logoORCID: https://orcid.org/0000-0002-0654-387X; Hornung, Veit und Liesz, Arthur (2021): Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade. In: Immunity, Bd. 54, Nr. 4: S. 648-659

Tanzer, Maria C.; Bludau, Isabell; Stafford, Che A.; Hornung, Veit und Mann, Matthias (2021): Phosphoproteome profiling uncovers a key role for CDKs in TNF signaling. In: Nature Communications, Bd. 12, Nr. 1, 6053

Wratil, Paul R.; Schmacke, Niklas A.; Karakoc, Burak; Dulovic, Alex; Junker, Daniel; Becker, Matthias; Rothbauer, Ulrich; Osterman, Andreas; Spaeth, Patricia M.; Ruhle, Adrian; Gapp, Madeleine; Schneider, Stephanie; Muenchhoff, Maximilian; Hellmuth, Johannes C.; Scherer, Clemens; Mayerle, Julia; Reincke, Martin; Behr, Jürgen; Kaab, Stefan; Zwissler, Bernhard; Bergwelt-Baildon, Michael von; Eberle, Josef; Kaderali, Lars; Schneiderhan-Marra, Nicole; Hornung, Veit und Keppler, Oliver T. (2021): Evidence for increased SARS-CoV-2 susceptibility and COVID-19 severity related to pre-existing immunity to seasonal coronaviruses. In: Cell Reports, Bd. 37, Nr. 13, 110169

Wratil, Paul R.; Schmacke, Niklas A.; Osterman, Andreas; Weinberger, Tobias; Rech, Jochen; Karakoc, Burak; Zeilberger, Mira; Steffen, Julius; Mueller, Tonina T.; Spaeth, Patricia M.; Stern, Marcel; Albanese, Manuel; Thun, Hella; Reinbold, Julia; Sandmeyer, Benedikt; Kressirer, Philipp; Grabein, Beatrice; Falkai, Peter; Adorjan, Kristina; Hornung, Veit; Kaderali, Lars; Klein, Matthias und Keppler, Oliver T. (2021): In-depth profiling of COVID-19 risk factors and preventive measures in healthcare workers. In: Infection, Bd. 50, Nr. 2: S. 381-394

Ghosh, Suvoshree; Kraus, Katrin; Biswas, Arijit; Mueller, Jens; Forin, Francesco; Singer, Heike; Höning, Klara; Hornung, Veit; Watzka, Matthias; Oldenburg, Johannes und Czogalla-Nitsche, Katrin J. (2021): GGCX variants leading to biallelic deficiency to gamma-carboxylate GRP cause skin laxity in VKCFD1 patients. In: Human Mutation, Bd. 43, Nr. 1: S. 42-55

Hopfner, Karl-Peter ORCID logoORCID: https://orcid.org/0000-0002-4528-8357 und Hornung, Veit ORCID logoORCID: https://orcid.org/0000-0002-4150-194X (18. Mai 2020): Molecular mechanisms and cellular functions of cGAS-STING signalling. In: Nature Reviews Molecular Cell Biology, Bd. 21: S. 501-521 [PDF, 13MB]

Lampl, Sandra; Janas, Marianne K.; Donakonda, Sainitin; Brugger, Marcus; Lohr, Kerstin; Schneider, Annika; Manske, Katrin; Sperl, Laura E.; Klaeger, Susan; Kuester, Bernhard; Wettmarshausen, Jennifer; Müller, Constanze; Laschinger, Melanie; Hartmann, Daniel; Hueser, Norber; Perocchi, Fabiana; Schmitt-Kopplin, Philippe; Hagn, Franz; Zender, Lars; Hornung, Veit; Borner, Christoph; Pichlmair, Andreas; Kashkar, Hamid; Klingenspor, Martin; Prinz, Marco; Schreiner, Sabrina; Conrad, Marcus; Jost, Philipp J.; Zischka, Hans; Steiger, Katja; Kroenke, Martin; Zehn, Dietmar; Protzer, Ulrike; Heikenwaelder, Mathias; Knolle, Percy A. und Wohlleber, Dirk (2020): Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes. In: Journal of Hepatology, Bd. 73, Nr. 6: S. 1347-1359

Schnatbaum, Karsten; Solis-Mezarino, Victor; Pokrovsky, Daniil; Schaefer, Frederike; Nagl, Dennis; Hornberger, Lars; Zerweck, Johannes; Knaute, Tobias; Avramova-Nehmer, Julia; Schutkowski, Mike; Hornung, Veit; Wenschuh, Holger; Voelker-Albert, Moritz Carl; Imhof, Axel und Reimer, Ulf (2020): New Approaches for Absolute Quantification of Stable-Isotope-Labeled Peptide Standards for Targeted Proteomics Based on a UV Active Tag. In: Proteomics, Bd. 20, Nr. 10, 2000007

Linder, Andreas; Bauernfried, Stefan; Cheng, Yiming; Albanese, Manuel; Jung, Christophe; Keppler, Oliver T. und Hornung, Veit (2020): CARD8 inflammasome activation triggers pyroptosis in human T cells. In: EMBO Journal, Bd. 39, Nr. 19, e105071 [PDF, 1MB]

Huppertz, Christine; Jager, Benedikt; Wieczorek, Grazyna; Engelhard, Peggy; Oliver, Stephen J.; Bauernfeind, Franz-Georg; Littlewood-Evans, Amanda; Welte, Tobias; Hornung, Veit und Prasse, Antje (2020): The NLRP3 inflammasome pathway is activated in sarcoidosis and involved in granuloma formation. In: European Respiratory Journal, Bd. 55, Nr. 3, 1900119

Michalski, Sebastian; de Oliveira Mann, Carina C.; Stafford, Che A.; Witte, Gregor; Bartho, Joseph; Lammens, Katja; Hornung, Veit und Hopfner, Karl-Peter (2020): Structural basis for sequestration and autoinhibition of cGAS by chromatin. In: Nature, Bd. 587, Nr. 7835: S. 678-682

Pinci, Francesca; Gaidt, Moritz M.; Jung, Christophe; Kuut, Gunnar; Jackson, Margaret A.; Bauernfried, Stefan und Hornung, Veit (2020): C-tag TNF: a reporter system to study TNF shedding. In: Journal of Biological Chemistry, Bd. 295, Nr. 52: S. 18065-18075

Lauterbach-Riviere, Lise; Bergez, Maiwenn; Moench, Saskia; Qu, Bingqian; Riess, Maximilian; Vondran, Florian W. R.; Liese, Juliane; Hornung, Veit; Urban, Stephan und König, Renate (2020): Hepatitis B Virus DNA is a Substrate for the cGAS/STING Pathway but is not Sensed in Infected Hepatocytes. In: Viruses-Basel, Bd. 12, Nr. 6, 592

Greulich, Wilhelm; Wagner, Mirko; Gaidt, Moritz M.; Stafford, Che; Cheng, Yiming; Linder, Andreas; Carell, Thomas und Hornung, Veit (27. November 2019): TLR8 Is a Sensor of RNase T2 Degradation Products. In: Cell, Bd. 179, Nr. 6: S. 1264-1275 [PDF, 2MB]

Hupa, Kristof Johannes; Stein, Kathy; Schneider, Ralf; Lysson, Mariola; Schneiker, Bianca; Hornung, Veit; Latz, Eicke; Iwakura, Yoichiro; Kalff, Jörg C. und Wehner, Sven (2019): AIM2 inflammasome-derived IL-1 beta induces postoperative ileus in mice. In: Scientific Reports, Bd. 9, 10602 [PDF, 1MB]

Andersen, Line Lykke; Terczynska-Dyla, Ewa; Mork, Nanna; Scavenius, Carsten; Enghild, Jan J.; Hoening, Klara; Hornung, Veit; Christiansen, Mette; Mogensen, Trine H. und Hartmann, Rune (2019): Frequently used bioinformatics tools overestimate the damaging effect of allelic variants. In: Genes and Immunity, Bd. 20, Nr. 1: S. 10-22

Paludan, Soren R.; Reinert, Line S. und Hornung, Veit (2019): DNA-stimulated cell death: implications for host defence, inflammatory diseases and cancer. In: Nature Reviews Immunology, Bd. 19, Nr. 3: S. 141-153

Metzger, Eric; Wang, Sheng; Urban, Sylvia; Willmann, Dominica; Schmidt, Andreas; Offermann, Anne; Allen, Anita; Sum, Manuela; Obier, Nadine; Cottard, Felicie; Ulferts, Svenja; Preca, Bogdan-Tiberius; Hermann, Bianca; Maurer, Jochen; Greschik, Holger; Hornung, Veit; Einsle, Oliver; Perner, Sven; Imhof, Axel; Jung, Manfred und Schuele, Roland (2019): KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells. In: Nature Structural & Molecular Biology, Bd. 26, Nr. 5

Gamm, Matthias von; Schaub, Annalisa; Jones, Alisha N.; Wolf, Christine; Behrens, Gesine; Lichti, Johannes; Essig, Katharina; Macht, Anna; Pircher, Joachim; Ehrlich, Andreas; Davari, Kathrin; Chauhan, Dhruv; Busch, Benjamin; Wurst, Wolfgang; Feederle, Regina; Feuchtinger, Annette; Tschoep, Matthias H.; Friedel, Caroline C.; Hauck, Stefanie M.; Sattler, Michael; Geerlof, Arie; Hornung, Veit; Heissmeyer, Vigo; Schulz, Christian; Heikenwalder, Mathias und Glasmacher, Elke (2019): Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3. In: Journal of Experimental Medicine, Bd. 216, Nr. 7: S. 1700-1723 [PDF, 6MB]

de Sousa-Pereira, Patricia; Abrantes, Joana; Bauernfried, Stefan; Pierini, Virginia; Esteves, Pedro Jose; Keppler, Oliver T.; Pizzato, Massimo; Hornung, Veit; Fackler, Oliver T. und Baldauf, Hanna-Mari (2019): The antiviral activity of rodent and lagomorph SERINC3 and SERINC5 is counteracted by known viral antagonists. In: Journal of General Virology, Bd. 100, Nr. 2: S. 278-288

Li, Yue; Fuehrer, Marita; Bahrami, Ehsan; Socha, Piotr; Klaudel-Dreszler, Maja; Bouzidi, Amira; Liu, Yanshan; Lehle, Anna S.; Magg, Thomas; Hollizeck, Sebastian; Rohlfs, Meino; Conca, Raffaele; Field, Michael; Warner, Neil; Mordechai, Slae; Shteyer, Eyal; Turner, Dan; Boukari, Rachida; Belbouab, Reda; Walz, Christoph; Gaidt, Moritz M.; Hornung, Veit; Baumann, Bernd; Pannicke, Ulrich; Al Idrissi, Eman; Alghamdi, Hamza Ali; Sepulveda, Fernando E.; Gil, Marine; Basile, Genevieve de Saint; Honig, Manfred; Koletzko, Sibylle; Muise, Aleixo M.; Snapper, Scott B.; Schwarz, Klaus; Klein, Christoph und Kotlarz, Daniel (2019): Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 116, Nr. 3: S. 970-975

Guenther, Saskia D.; Fritsch, Melanie; Seeger, Jens M.; Schiffmann, Lars M.; Snipas, Scott J.; Coutelle, Maria; Kufer, Thomas A.; Higgins, Paul G.; Hornung, Veit; Bernardini, Maria L.; Hoening, Stefan; Kroenke, Martin; Salvesen, Guy S. und Kashkar, Hamid (2019): Cytosolic Gram-negative bacteria prevent apoptosis by inhibition of effector caspases through lipopolysaccharide. In: Nature Microbiology, Bd. 5, Nr. 2

Ranjbar, Shahin; Haridas, Viraga; Nambu, Aya; Jasenosky, Luke D.; Sadhukhan, Supriya; Ebert, Thomas S.; Hornung, Veit; Cassell, Gail H.; Falvo, James und Goldfeld, Anne E. (2019): Cytoplasmic RNA Sensor Pathways and Nitazoxanide Broadly Inhibit Intracellular Mycobacterium tuberculosis Growth. In: Iscience, Bd. 22

Bergez, Maiewenn; Weber, Jakob; Riess, Maximilian; Erdbeer, Alexander; Seifried, Janna; Stanke, Nicole; Munz, Clara; Hornung, Veit; König, Renate und Lindemann, Dirk (2019): Insights into Innate Sensing of Prototype Foamy Viruses in Myeloid Cells. In: Viruses-Basel, Bd. 11, Nr. 12, 1095

Shao, Lulu; Hou, Weizhou; Scharping, Nicole E.; Vendetti, Frank P.; Srivastava, Rashmi; Roy, Chandra Nath; Menk, Ashley V.; Wang, Yiyang; Chauvin, Joe-Marc; Karukonda, Pooja; Thorne, Stephen H.; Hornung, Veit; Zarour, Hassane M.; Bakkenist, Christopher J.; Delgoffe, Greg M. und Sarkar, Saumendra N. (2019): IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell. In: Cancer Immunology Research, Bd. 7, Nr. 8: S. 1258-1266

Fisch, Daniel; Bando, Hironori; Clough, Barbara; Hornung, Veit; Yamamoto, Masahiro; Shenoy, Avinash R. und Frickel, Eva-Maria (2019): Human GBP1 is a microbe-specific gatekeeper of macrophage apoptosis and pyroptosis. In: EMBO Journal, Bd. 38, Nr. 13, e100926

Gaidt, Moritz M. und Hornung, Veit (2018): The NLRP3 Inflammasome Renders Cell Death Pro-inflammatory. In: Journal of Molecular Biology, Bd. 430, Nr. 2: S. 133-141

Surup, Frank; Chauhan, Dhruv; Niggemann, Jutta; Bartok, Eva; Herrmann, Jennifer; Keck, Matthias; Zander, Wiebke; Stadler, Marc; Hornung, Veit und Müller, Rolf (2018): Activation of the NLRP3 Inflammasome by Hyaboron, a New Asymmetric Boron-Containing Macrodiolide from the Myxobacterium Hyalangium minutum. In: ACS Chemical Biology, Bd. 13, Nr. 10: S. 2981-2988

Czogalla, Katrin J.; Liphardt, Kerstin; Hoening, Klara; Hornung, Veit; Biswas, Arijit; Watzka, Matthias und Oldenburg, Johannes (2018): VKORC1 and VKORC1L1 have distinctly different oral anticoagulant dose-response characteristics and binding sites. In: Blood Advances, Bd. 2, Nr. 6: S. 691-702

Chauhan, Dhruv; Bartok, Eva; Gaidt, Moritz M.; Bock, Florian J.; Herrmann, Jennifer; Seeger, Jens M.; Broz, Petr; Beckmann, Roland; Kashkar, Hamid; Tait, Stephen W. G.; Müller, Rolf und Hornung, Veit (2018): BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1beta Maturation in Macrophages. In: Cell Reports, Bd. 25, Nr. 9, P2354-2368.E5

Karlstetter, Marcus; Kopatz, Jens; Aslanidis, Alexander; Shahraz, Anahita; Caramoy, Albert; Linnartz-Gerlach, Bettina; Lin, Yuchen; Lückoff, Anika; Fauser, Sascha; Düker, Katharina; Claude, Janine; Wang, Yiner; Ackermann, Johannes; Schmidt, Tobias; Hornung, Veit; Skerka, Christine; Langmann, Thomas und Neumann, Harald (2017): Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina. In: Embo Molecular Medicine, Bd. 9, Nr. 2: S. 154-166

Schneider, Constanze; Oellerich, Thomas; Baldauf, Hanna-Mari; Schwarz, Sarah-Marie; Thomas, Dominique; Flick, Robert; Bohnenberger, Hanibal; Kaderali, Lars; Stegmann, Lena; Cremer, Anjali; Martin, Margarethe; Lohmeyer, Julian; Michaelis, Martin; Hornung, Veit; Schliemann, Christoph; Berdel, Wolfgang E.; Hartmann, Wolfgang; Wardelmann, Eva; Comoglio, Federico; Hansmann, Martin-Leo; Yakunin, Alexander F.; Geisslinger, Gerd; Stroebel, Philipp; Ferreiros, Nerea; Serve, Hubert; Keppler, Oliver T. und Cinatl, Jindrich (2017): SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia. In: Nature Medicine, Bd. 23, Nr. 2: S. 250-255

Gaidt, Moritz M.; Ebert, Thomas S.; Chauhan, Dhruv; Ramshorn, Katharina; Pinci, Francesca; Zuber, Sarah; O'Duill, Fionan; Schmid-Burgk, Jonathan L.; Hoss, Florian; Buhmann, Raymund; Wittmann, Georg; Latz, Eicke; Subklewe, Marion und Hornung, Veit (2017): The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3. In: Cell, Bd. 171, Nr. 5: S. 1110-1124

Kim-Hellmuth, Sarah; Bechheim, Matthias; Pütz, Benno; Mohammadi, Pejman; Nedelec, Yohann; Giangreco, Nicholas; Becker, Jessica; Kaiser, Vera; Fricker, Nadine; Beier, Esther; Boor, Peter; Castel, Stephane E.; Nöthen, Markus M.; Barreiro, Luis B.; Pickrell, Joseph K.; Müller-Myhsok, Bertram; Lappalainen, Tuuli; Schumacher, Johannes und Hornung, Veit (2017): Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations. In: Nature Communications, Bd. 8 [PDF, 1MB]

Czogalla, Katrin J.; Biswas, Arijit; Höning, Klara; Hornung, Veit; Liphardt, Kerstin; Watzka, Matthias und Oldenburg, Johannes (2017): Warfarin and vitamin K compete for binding to Phe55 in human VKOR. In: Nature Structural & Molecular Biology, Bd. 24, Nr. 1: S. 77-85

Ghosh, Sreya; Wallerath, Christina; Covarrubias, Sergio; Hornung, Veit; Carpenter, Susan und Fitzgerald, Katherine A. (2017): The PYHIN Protein p205 Regulates the Inflammasome by Controlling Asc Expression. In: Journal of Immunology, Bd. 199, Nr. 9: S. 3249-3260

Heuser, Christoph; Gotot, Janine; Piotrowski, Eveline Christina; Philipp, Marie-Sophie; Courreges, Christina Johanna Felicia; Otte, Martin Sylvester; Guo, Linlin; Schmid-Burgk, Jonathan Leo; Hornung, Veit; Heine, Annkristin; Knolle, Percy Alexander; Garbi, Natalio; Serfling, Edgar; Evaristo, Cesar; Thaiss, Friedrich und Kurts, Christian (2017): Prolonged IKK beta Inhibition Improves Ongoing CTL Antitumor Responses by Incapacitating Regulatory T Cells. In: Cell Reports, Bd. 21, Nr. 3: S. 578-586

Andreeva, Liudmila; Hiller, Björn; Kostrewa, Dirk; Lässig, Charlotte; Oliveira Mann, Carina C. de; Drexler, David Jan; Maiser, Andreas; Gaidt, Moritz; Leonhardt, Heinrich; Hornung, Veit und Hopfner, Karl-Peter (2017): cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders. In: Nature, Bd. 549, Nr. 7672: S. 394-398

Engel, Christina; Brügmann, Grethe; Lambing, Silke; Mühlenbeck, Larissa H.; Marx, Samira; Hagen, Christian; Horvath, Dorottya; Goldeck, Marion; Ludwig, Janos; Herzner, Anna-Maria; Drijfhout, Jan W.; Wenzel, Daniela; Coch, Christoph; Tüting, Thomas; Schlee, Martin; Hornung, Veit; Hartmann, Gunther und Boorn, Jasper G. van den (2017): RIG-I Resists Hypoxia-Induced Immunosuppression and Dedifferentiation. In: Cancer Immunology Research, Bd. 5, Nr. 6: S. 455-467

Gaidt, Moritz M. und Hornung, Veit (2017): Alternative inflammasome activation enables IL-1 beta release from living cells. In: Current Opinion in Immunology, Bd. 44: S. 7-13

Baum, Rebecca; Sharma, Shruti; Organ, Jason M.; Jakobs, Christopher; Hornung, Veit; Burr, David B.; Marshak-Rothstein, Ann; Fitzgerald, Katherine A. und Gravallese, Ellen M. (2017): STING Contributes to Abnormal Bone Formation Induced by Deficiency of DNase II in Mice. In: Arthritis & Rheumatology, Bd. 69, Nr. 2: S. 460-471

Schmid-Burgk, Jonathan L.; Höning, Klara; Ebert, Thomas S. und Hornung, Veit (2016): CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism. In: Nature Communications, Bd. 7, 12338 [PDF, 4MB]

Pépin, Genevieve; Ferrand, Jonathan; Höning, Klara; Jayasekara, W. Samantha N.; Cain, Jason E.; Behlke, Mark A.; Gough, Daniel J.; Williams, Bryan R. G.; Hornung, Veit und Gantier, Michael P. (2016): Cre-dependent DNA recombination activates a STING-dependent innate immune response. In: Nucleic Acids Research, Bd. 44, Nr. 11: S. 5356-5364 [PDF, 1MB]

Paijo, Jennifer; Döring, Marius; Spanier, Julia; Grabski, Elena; Nooruzzaman, Mohammed; Schmidt, Tobias; Witte, Gregor; Messerle, Martin; Hornung, Veit; Kaever, Volkhard und Kalinke, Ulrich (2016): cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells.
In: PLOS Pathogens 12(4), e1005546 [PDF, 1MB]

Ghosh, Arundhati; Sampath, Padmavathi; Zhu, Jianzhong; Hornung, Veit; Thorne, Stephen und Sarkar, Saumendra N. (2016): Modulation of cellular immune response by 2 '-5 ' Oligoadenylate Synthetase - like (OASL) proteins during DNA virus infection. In: Journal of Immunology, Bd. 196

Bauernfeind, Franz; Niepmann, Sven; Knolle, Percy A. und Hornung, Veit (2016): Aging-Associated TNF Production Primes Inflammasome Activation and NLRP3-Related Metabolic Disturbances. In: Journal of Immunology, Bd. 197, Nr. 7: S. 2900-2908

Kainulainen, Markus; Lau, Simone; Samuel, Charles E.; Hornung, Veit und Weber, Friedemann (2016): NSs Virulence Factor of Rift Valley Fever Virus Engages the F-Box Proteins FBXW11 and beta-TRCP1 To Degrade the Antiviral Protein Kinase PKR. In: Journal of Virology, Bd. 90, Nr. 13: S. 6140-6147

Gaidt, Moritz M. und Hornung, Veit (2016): Pore formation by GSDMD is the effector mechanism of pyroptosis. In: Embo Journal, Bd. 35, Nr. 20: S. 2167-2169

Schmid-Burgk, Jonathan L.; Chauhan, Dhruv; Schmidt, Tobias; Ebert, Thomas S.; Reinhardt, Julia; Endl, Elmar und Hornung, Veit (2016): A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation. In: Journal of Biological Chemistry, Bd. 291, Nr. 1: S. 103-109

Boorn, Jasper G. van den; Jakobs, Christopher; Hagen, Christian; Renn, Marcel; Luiten, Rosalie M.; Melief, Cornelis J. M.; Tüting, Thomas; Garbi, Natalio; Hartmann, Gunther und Hornung, Veit (2016): Inflammasome-Dependent Induction of Adaptive NK Cell Memory. In: Immunity, Bd. 44, Nr. 6: S. 1406-1421

Krapp, Christian; Hotter, Dominik; Gawanbacht, Ali; McLaren, Paul J.; Kluge, Silvia F.; Stürzel, Christina M.; Mack, Katharina; Reith, Elisabeth; Engelhart, Susanne; Ciuffi, Angela; Hornung, Veit; Sauter, Daniel; Telenti, Amalio und Kirchhoff, Frank (2016): Guanylate Binding Protein (GBP) 5 Is an Interferon-Inducible Inhibitor of HIV-1 Infectivity. In: Cell Host & Microbe, Bd. 19, Nr. 4: S. 504-514

Xu, Shuting; Ducroux, Aurélie; Ponnurangam, Aparna; Vieyres, Gabrielle; Franz, Sergej; Müsken, Mathias; Zillinger, Thomas; Malassa, Angelina; Ewald, Ellen; Hornung, Veit; Barchet, Winfried; Häussler, Susanne; Pietschmann, Thomas und Goffinet, Christine (2016): cGAS-Mediated Innate Immunity Spreads Intercellularly through HIV-1 Env-Induced Membrane Fusion Sites. In: Cell Host & Microbe, Bd. 20, Nr. 4: S. 443-457

Gaidt, Moritz M.; Ebert, Thomas S.; Chauhan, Dhruv; Schmidt, Tobias; Schmid-Burgk, Jonathan L.; Rapino, Francesca; Robertson, Avril A. B.; Cooper, Matthew A.; Graf, Thomas und Hornung, Veit (2016): Human Monocytes Engage an Alternative Inflammasome Pathway. In: Immunity, Bd. 44, Nr. 4: S. 833-846

Roers, Axel; Hiller, Björn und Hornung, Veit (2016): Recognition of Endogenous Nucleic Acids by the Innate Immune System. In: Immunity, Bd. 44, Nr. 4: S. 739-754

Laessig, Charlotte; Matheisl, Sarah; Sparrer, Konstantin M. J.; Mann, Carina C. de Oliveira; Moldt, Manuela; Patel, Jenish R.; Goldeck, Marion; Hartmann, Gunther; Garcia-Sastre, Adolfo; Hornung, Veit; Conzelmann, Karl-Klaus; Beckmann, Roland und Hopfner, Karl-Peter (2015): ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA. In: eLife, Bd. 4, e10859 [PDF, 2MB]

Konferenzbeitrag

Xu, Shuting; Ducroux, Aurelie; Ponnurangam, Aparna; Franz, Sergej; Vieyres, Gabrielle; Müsken, Mathias; Zillinger, Thomas; Malassa, Angelina; Ewald, Ellen; Hornung, Veit; Barchet, Winfried; Häussler, Susanne; Pietschmann, Thomas und Goffinet, Christine (2016): cGAMP transfers intercellularly via HIV-1 Env-mediated cell-cell fusion sites and triggers an innate immune response in primary target cells. Frontiers of Retrovirology Conference 2016, Erlangen, Germany, Montag, 12. September bis Mittwoch, 14. September 2016. Retrovirology. Bd. 13, Nr. Suppl. 1, P64 BioMed Central. [PDF, 3MB]

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