Publikationen von Kirchner, Thomas

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Anzahl der Publikationen: 171

Herausgeberschaft

Kern, Margit; Kirchner, Thomas und Kohle, Hubertus

(Hrsg.) (2004): Geschichte und Ästhetik. Festschrift für Werner Busch zum 60. Geburtstag. München, Berlin: Deutscher Kunstverlag.

Zeitschriftenartikel

Pretzsch, Elise; Neumann, Jens; Nieß, Hanno; Pretzsch, Charlotte M.; Hofmann, F.O.; Kirchner, Thomas; Klauschen, Frederick; Werner, Jens; Angele, Martin K. und Kumbrink, Jörg (2024): Comparative transcriptomic analyses reveal activation of the epithelial-mesenchymal transition program in non-metastasizing low grade pseudomyxoma peritonei. In: Pathology - Research and Practice, Bd. 254, Nr. 155129: S. 1-9 [PDF, 3MB]

Jacob, Sven; Balonov, Ilja; Jurinovic, Vindi; Heiliger, Christian; Tschaidse, Tengis; Kumbrink, Jörg; Kirchner, Thomas; Werner, Jens; Angele, Martin K.; Michl, Marlies und Neumann, Jens (2024): TGFβ signalling pathway impacts brain metastases profiles in locally advanced colorectal cancer. In: Clinical & Experimental Metastasis [Forthcoming]

Michl, Marlies; Taverna, Francesco; Woischke, Christine; Li, Pan; Klauschen, Frederick; Kirchner, Thomas; Heinemann, Volker

; Bergwelt-Baildon, Michael von

; Stahler, Arndt; Herold, Tobias Marcus; Jurinovic, Vindi; Engel, Jutta; Kumbrink, Jörg

und Neumann, Jens (2024): Identification of a gene expression signature associated with brain metastasis in colorectal cancer. In: Clinical and Translational Oncology, Bd. 26: S. 1886-1895 [PDF, 848kB]

Lee, Olivia W.

; Rodrigues, Calvin; Lin, Shu-Hong; Luo, Wen; Jones, Kristine; Brown, Derek W.; Zhou, Weiyin; Karlins, Eric; Khan, Sairah M.; Baulande, Sylvain; Raynal, Virginie; Surdez, Didier; Reynaud, Stephanie; Rubio, Rebeca Alba; Zaidi, Sakina; Grossetête, Sandrine; Ballet, Stelly; Lapouble, Eve; Laurence, Valérie; Pierron, Gaelle; Gaspar, Nathalie; Corradini, Nadège; Marec-Bérard, Perrine; Rothman, Nathaniel; Dagnall, Casey L.; Burdett, Laurie; Manning, Michelle; Wyatt, Kathleen; Yeager, Meredith; Chari, Raj; Leisenring, Wendy M.; Kulozik, Andreas E.; Kriebel, Jennifer; Meitinger, Thomas; Strauch, Konstantin; Kirchner, Thomas; Dirksen, Uta; Mirabello, Lisa; Tucker, Margaret A.; Tirode, Franck; Armstrong, Gregory T.; Bhatia, Smita; Robison, Leslie L.; Yasui, Yutaka; Romero-Pérez, Laura; Hartmann, Wolfgang; Metzler, Markus; Diver, W. Ryan; Lori, Adriana; Freedman, Neal D.; Hoover, Robert N.; Morton, Lindsay M.; Chanock, Stephen J.; Grünewald, Thomas G.P.; Delattre, Olivier und Machiela, Mitchell J.

(2023): Targeted long-read sequencing of the Ewing sarcoma 6p25.1 susceptibility locus identifies germline-somatic interactions with EWSR1-FLI1 binding. In: American Journal of Human Genetics, Bd. 110, Nr. 3: S. 427-441

Jaitner, Stefanie; Pretzsch, Elise; Neumann, Jens; Schäffauer, Achim; Schiemann, Matthias; Angele, Martin; Kumbrink, Jörg; Schwitalla, Sarah; Greten, Florian R; Brandl, Lydia; Klauschen, Frederick; Horst, David; Kirchner, Thomas und Jung, Andreas (8. November 2022): Olfactomedin 4 associates with expression of differentiation markers but not with properties of cancer stemness, EMT nor metastatic spread in colorectal cancer. In: The Journal of Pathology: Clinical Research, Bd. 9, Nr. 1: S. 73-85 [PDF, 1MB]

Paul, Tanja; Ledderose, Stephan; Bartsch, Harald; Sun, Na; Soliman, Sarah; Märkl, Bruno; Ruf, Viktoria; Herms, Jochen; Stern, Marcel; Keppler, Oliver T.; Delbridge, Claire; Müller, Susanna; Piontek, Guido; Kimoto, Yuki Schneider; Schreiber, Franziska; Williams, Tracy Ann; Neumann, Jens; Knösel, Thomas; Schulz, Heiko; Spallek, Ria; Graw, Matthias; Kirchner, Thomas; Walch, Axel und Rudelius, Martina (24. März 2022): Adrenal tropism of SARS-CoV-2 and adrenal findings in a post-mortem case series of patients with severe fatal COVID-19. In: Nature Communications, Bd. 13 [PDF, 5MB]

Weber, Peter; Kunstner, Axel; Hess, Julia; Unger, Kristian; Marschner, Sebastian; Idel, Christian; Ribbat-Idel, Julika; Baumeister, Philipp; Gires, Olivier; Walz, Christoph; Rietzler, Sibylle; Valeanu, Laura; Herkommer, Timm; Kreutzer, Lisa; Klymenko, Olena; Drexler, Guido; Kirchner, Thomas; Maihofer, Cornelius; Ganswindt, Ute; Walch, Axel; Sterr, Michael; Lickert, Heiko; Canis, Martin; Rades, Dirk; Perner, Sven; Diaz, Mauricio Berriel; Herzig, Stefan; Lauber, Kirsten; Wollenberg, Barbara; Busch, Hauke; Belka, Claus und Zitzelsberger, Horst (2022): Therapy-Related Transcriptional Subtypes in Matched Primary and Recurrent Head and Neck Cancer. In: Clinical Cancer Research, Bd. 28, Nr. 5: S. 1038-1052

Heinrich, Kathrin; Miller-Phillips, Lisa; Ziemann, Frank; Hasselmann, Korbinian; Rühlmann, Katharina; Flach, Madeleine; Biro, Dorottya; Bergwelt-Baildon, Michael von; Holch, Julian; Herold, Tobias; Baumgarten, Louisa von; Greif, Philip A.

; Jeremias, Irmela; Wuerstlein, Rachel; Casuscelli, Jozefina; Spitzweg, Christine; Seidensticker, Max; Renz, Bernhard; Corradini, Stefanie; Baumeister, Philipp; Goni, Elisabetta; Tufman, Amanda; Jung, Andreas; Kumbrink, Jörg; Kirchner, Thomas; Klauschen, Frederick; Metzeler, Klaus H.; Heinemann, Volker und Westphalen, C. Benedikt

(2022): Lessons learned: the first consecutive 1000 patients of the CCCMunich(LMU) Molecular Tumor Board. In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 5: S. 1905-1915 [PDF, 728kB]

Torlot, Lucien; Jarzab, Anna; Albert, Johanna; Pok-Udvari, Agnes; Stahler, Arndt; Holch, Julian Walter; Gerlinger, Marco; Heinemann, Volker; Klauschen, Frederick; Kirchner, Thomas; Kumbrink, Jörg; Küster, Bernhard und Jung, Andreas

(2022): Proteomics uncover EPHA2 as a potential novel therapeutic target in colorectal cancer cell lines with acquired cetuximab resistance. In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 2: S. 669-682 [PDF, 2MB]

Neuberger, Michael

; Jungbluth, Achim; Irlbeck, Michael; Streitparth, Florian; Burian, Maria; Kirchner, Thomas; Werner, Jens; Rudelius, Martina und Knösel, Thomas (2022): Duodenal tropism of SARS-CoV-2 and clinical findings in critically ill COVID-19 patients. In: Infection, Bd. 50, Nr. 5: S. 1111-1120 [PDF, 1MB]

Fischer, Laura E.

; Stintzing, Sebastian; Weikersthal, Ludwig Fischer von; Modest, Dominik P.; Decker, Thomas; Kiani, Alexander

; Kaiser, Florian; Al-Batran, Salah-Eddin; Heintges, Tobias; Lerchenmüller, Christian; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Stauch, Martina; Scheithauer, Werner; Giessen-Jung, Clemens; Uhlig, Jens; Peuser, Bettina; Denzlinger, Claudio; Stahler, Arndt; Weiss, Lena; Heinrich, Kathrin; Held, Swantje; Jung, Andreas; Kirchner, Thomas und Heinemann, Volker (2022): Efficacy of FOLFIRI plus cetuximab vs FOLFIRI plus bevacizumab in 1st-line treatment of older patients with RAS wild-type metastatic colorectal cancer: an analysis of the randomised trial FIRE-3. In: British Journal of Cancer, Bd. 127, Nr. 5: S. 836-843 [PDF, 788kB]

Kumbrink, Jorg; Bohlmann, Lisa; Mamlouk, Soulafa; Redmer, Torben; Peilstocker, Daniela; Li, Pan; Lorenzen, Sylvie; Alguel, Hana; Kasper, Stefan; Hempel, Dirk; Kaiser, Florian; Michl, Marlies; Bartsch, Harald; Neumann, Jens; Klauschen, Frederick; Bergwelt-Baildon, Michael von; Modest, Dominik Paul; Stahler, Arndt; Stintzing, Sebastian; Jung, Andreas; Kirchner, Thomas; Schäfer, Reinhold; Heinemann, Volker und Holch, Julian W. (2022): Serial Analysis of Gene Mutations and Gene Expression during First-Line Chemotherapy against Metastatic Colorectal Cancer: Identification of Potentially Actionable Targets within the Multicenter Prospective Biomarker Study REVEAL. In: Cancers, Bd. 14, Nr. 15 [PDF, 4MB]

Orth, Martin F.; Surdez, Didier; Faehling, Tobias; Ehlers, Anna C.; Marchetto, Aruna; Grossetete, Sandrine; Volckmann, Richard; Zwijnenburg, Danny A.; Gerke, Julia S.; Zaidi, Sakina; Alonso, Javier; Sastre, Ana; Baulande, Sylvain; Sill, Martin; Cidre-Aranaz, Florencia; Ohmura, Shunya; Kirchner, Thomas; Hauck, Stefanie M.; Reischl, Eva; Gymrek, Melissa; Pfister, Stefan M.; Strauch, Konstantin; Koster, Jan; Delattre, Olivier und Grunewald, Thomas G. . P. (2022): Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation. In: Cell Reports, Bd. 41, Nr. 10, 111761

Stahler, Arndt; Modest, Dominik P.; Fischer von Weikersthal, Ludwig; Kaiser, Florian; Decker, Thomas; Held, Swantje; Graeven, Ullrich; Schwaner, Ingo; Denzlinger, Claudio; Schenk, Michael; Kurreck, Annika; Heinrich, Kathrin; Giessen-Jung, Clemens; Neumann, Jens; Kirchner, Thomas; Jung, Andreas; Stintzing, Sebastian und Heinemann, Volker (2022): First-line fluoropyrimidine plus bevacizumab followed by irinotecan-escalation versus initial fluoropyrimidine, irinotecan and bevacizumab in patients with metastatic colorectal cancer - Final survival and per-protocol analysis of the randomised XELAVIRI trial (AIO KRK 0110). In: European Journal of Cancer, Bd. 173: S. 194-203

Boos, Sophie L.; Loevenich, Leon P.; Vosberg, Sebastian; Engleitner, Thomas; Öllinger, Rupert; Kumbrink, Joerg; Rokavec, Matjaz; Michl, Marlies; Greif, Philipp A.; Jung, Andreas; Hermeking, Heiko; Neumann, Jens; Kirchner, Thomas; Rad, Roland und Jung, Peter (2022): Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer. In: Cellular and Molecular Gastroenterology and Hepatology, Bd. 13, Nr. 2: S. 517-540

Pretzsch, Elise; Boesch, Florian; Todorova, Rumyana; Niess, Hanno; Jacob, Sven; Guba, Markus; Kirchner, Thomas; Werner, Jens; Klauschen, Frederick; Angele, Martin K. und Neumann, Jens (2022): Molecular subtyping of gastric cancer according to ACRG using immunohistochemistry - Correlation with clinical parameters. In: Pathology, Research and Practice, Bd. 231, 153797

Jung, Peter; Horst, David; Kirchner, Thomas; Klauschen, Frederick und Neumann, Jens (2022): AURKA is a prognostic biomarker for good overall survival in stage II colorectal cancer patients. In: Pathology, Research and Practice, Bd. 235, 153936

Ilmer, Matthias; Renz, Bernhard W.; Kuehn, Florian; Drefs, Moritz; Koliogiannis, Dionysios; Werner, Jens; Kirchner, Thomas; Horst, David und Woischke, Christine (2022): PBXIP1-An indicator for poor outcome and metastatic spread in colorectal cancer. In: Pathology, Research and Practice, Bd. 236, 153993

Voeltzke, Kai; Scharov, Katerina; Funk, Cornelius Maximilian; Kahler, Alisa; Picard, Daniel; Hauffe, Laura; Orth, Martin F.; Remke, Marc; Esposito, Irene; Kirchner, Thomas; Schramm, Alexander; Rotblat, Barak; Grunewald, Thomas G. P.; Reifenberger, Guido und Leprivier, Gabriel (2022): EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma. In: Cell Death Discovery, Bd. 8, Nr. 1, 157

Loevenich, Leon P.; Tschurtschenthaler, Markus; Rokavec, Matjaz; Silva, Miguel G.; Jesinghaus, Moritz; Kirchner, Thomas; Klauschen, Frederick; Saur, Dieter; Neumann, Jens; Hermeking, Heiko und Jung, Peter (2022): SMAD4 Loss Induces c-MYC-Mediated NLE1 Upregulation to Support Protein Biosynthesis, Colorectal Cancer Growth, and Metastasis. In: Cancer Research, Bd. 82, Nr. 24: S. 4604-4623

Cidre-Aranaz, Florencia; Li, Jing; Hoelting, Tilman L. B.; Orth, Martin F.; Imle, Roland; Kutschmann, Stefanie; Ammirati, Giuli; Ceranski, Katharina; Carreno-Gonzalez, Martha Julia; Kasan, Merve; Marchetto, Aruna; Funk, Cornelius M.; Bestvater, Felix; Bersini, Simone; Arrigoni, Chiara; Moretti, Matteo; Thiel, Uwe; Baumhoer, Daniel; Sahm, Felix; Pfister, Stefan M.; Hartmann, Wolfgang; Dirksen, Uta; Romero-Perez, Laura; Banito, Ana; Ohmura, Shunya; Musa, Julian; Kirchner, Thomas; Knott, Maximilian M. L. und Grunewald, Thomas G. P. (2022): Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma. In: Molecular Cancer, Bd. 21, Nr. 1, 1

Fischer, Laura E.; Stintzing, Sebastian; Heinemann, Volker; Keilholz, Ulrich; Keune, Dietmar; Vollbrecht, Claudia; Burmeister, Thomas; Kind, Andreas; Weiss, Lena; Horst, David; Kirchner, Thomas; Klauschen, Frederick; Jung, Andreas; Westphalen, Christoph Benedikt und Jelas, Ivan (2022): Liquid Biopsy in Colorectal Cancer: Quo Vadis? Implementation of Liquid Biopsies in Routine Clinical Patient Care in Two German Comprehensive Cancer Centers. In: Frontiers in Oncology, Bd. 12, 870411

Hess, Julia; Unger, Kristian; Maihoefer, Cornelius; Schuettrumpf, Lars; Weber, Peter; Marschner, Sebastian; Wintergerst, Ludmila; Pflugradt, Ulrike; Baumeister, Philipp; Walch, Axel; Woischke, Christine; Kirchner, Thomas; Werner, Martin; Soerensen, Kristin; Baumann, Michael; Tinhofer, Ingeborg; Combs, Stephanie E.; Debus, Juergen; Schaefer, Henning; Krause, Mechthild; Linge, Annett; Gruen, Jens von der; Stuschke, Martin; Zips, Daniel; Canis, Martin; Lauber, Kirsten; Ganswindt, Ute; Henke, Michael; Zitzelsberger, Horst und Belka, Claus (2022): Integration of p16/HPV DNA Status with a 24-miRNA-Defined Molecular Phenotype Improves Clinically Relevant Stratification of Head and Neck Cancer Patients. In: Cancers, Bd. 14, Nr. 15, 3745

Siemens, Helge; Neumann, Jens; Jackstadt, Rene; Mansmann, Ulrich

; Horst, David; Kirchner, Thomas und Hermeking, Heiko (2022): Correction: Detection of miR-34a Promoter Methylation in Combination with Elevated Expression of c-Met and β-Catenin Predicts Distant Metastasis of Colon Cancer. In: Clinical Cancer Research, Bd. 28, Nr. 8: S. 1739

Tawk, Bouchra; Wirkner, Ute; Schwager, Christian; Rein, Katrin; Zaoui, Karim; Federspil, Philippe A.; Adeberg, Sebastian; Linge, Annett; Ganswindt, Ute; Hess, Julia; Unger, Kristian; Tinhofer, Ingeborg; Budach, Volker; Lohaus, Fabian; Krause, Mechthild; Guberina, Maja; Stuschke, Martin; Balermpas, Panagiotis; Rodel, Claus; Grosu, Anca L.; Schaefer, Henning; Zips, Daniel; Combs, Stephanie E.; Pigorsch, Steffi; Zitzelsberger, Horst; Baumeister, Philipp; Kirchner, Thomas; Bewerunge-Hudler, Melanie; Weichert, Wilko; Hess, Jochen; Herpel, Esther; Belka, Claus; Baumann, Michael; Debus, Jürgen und Abdollahi, Amir (2021): Tumor DNA-methylome derived epigenetic fingerprint identifies HPV-negative head and neck patients at risk for locoregional recurrence after postoperative radiochemotherapy. In: International Journal of Cancer, Bd. 150, Nr. 4: S. 603-616

Sultova, Elena; Westphalen, C. Benedikt; Jung, Andreas; Kumbrink, Jörg; Kirchner, Thomas; Mayr, Doris; Rudelius, Martina; Ormanns, Steffen; Heinemann, Volker; Metzeler, Klaus H.; Greif, Philipp A.; Hester, Anna; Mahner, Sven; Harbeck, Nadia und Würstlein, Rachel (2021): Implementation of Precision Oncology for Patients with Metastatic Breast Cancer in an Interdisciplinary MTB Setting. In: Diagnostics, Bd. 11, Nr. 4, 733

Jacob, Sven; Jurinovic, Vindi; Lampert, Christopher; Pretzsch, Elise; Kumbrink, Jörg; Neumann, Jens; Haoyu, Ren; Renz, Bernhard W.; Kirchner, Thomas; Guba, Markus O.; Werner, Jens; Angele, Martin K. und Bösch, Florian (2021): The association of immunosurveillance and distant metastases in colorectal cancer. In: Journal of cancer research and clinical oncology, Bd. 147, Nr. 11: S. 3333-3341 [PDF, 1MB]

Heinrich, Kathrin; Modest, Dominik P.; Ricard, Ingrid; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kaiser, Florian; Graeven, Ullrich; Uhlig, Jens; Schenk, Michael; Freiberg-Richter, Jens; Peuser, Bettina; Denzlinger, Claudio; Giessen-Jung, Clemens; Stahler, Arndt; Michl, Marlies; Held, Swantje; Jung, Andreas; Kirchner, Thomas; Stintzing, Sebastian und Heinemann, Volker (2021): Gender-dependent survival benefit from first-line irinotecan in metastatic colorectal cancer. Subgroup analysis of a phase III trial (XELAVIRI-study, AIO-KRK-0110). In: European Journal of Cancer, Bd. 147: S. 128-139

Heydt, Carina; Woelwer, Christina B.; Camacho, Oscar Velazquez; Wagener-Ryczek, Svenja; Pappesch, Roberto; Siemanowski, Janna; Rehker, Jan; Haller, Florian; Agaimy, Abbas; Worm, Karl; Herold, Thomas; Pfarr, Nicole; Weichert, Wilko; Kirchner, Thomas; Jung, Andreas; Kumbrink, Joerg; Goering, Wolfgang; Esposito, Irene; Buettner, Reinhard; Hillmer, Axel M. und Merkelbach-Bruse, Sabine (2021): Detection of gene fusions using targeted next-generation sequencing: a comparative evaluation. In: Springer Nature Medical Genomics, Bd. 14, Nr. 1, 62

Jacob, Sven; Bösch, Florian; Schoenberg, Markus B.; Pretzsch, Elise; Lampert, Christopher; Haoyu, Ren; Renz, Bernhard W.; Michl, Marlies; Kumbrink, Jörg; Kirchner, Thomas; Werner, Jens; Angele, Martin K. und Neumann, Jens (2021): Expression of CIB1 correlates with colorectal liver metastases but not with peritoneal carcinomatosis. In: BMC Cancer, Bd. 21, Nr. 1, 1243

Jacob, Sven; Jurinovic, Vindi; Lampert, Christopher; Pretzsch, Elise; Kumbrink, Jörg; Neumann, Jens; Ren, Haoyu; Renz, Bernhard W.; Kirchner, Thomas; Guba, Markus O.; Werner, Jens; Angele, Martin K. und Boesch, Florian (2021): The association of immunosurveillance and distant metastases in colorectal cancer. In: Journal of Cancer Research and Clinical Oncology, Bd. 147, Nr. 11: S. 3333-3341

Jurmeister, Philipp; Vollbrecht, Claudia; Joehrens, Korinna; Aust, Daniela; Behnke, Anke; Stenzinger, Albrecht; Penzel, Roland; Endris, Volker; Schirmacher, Peter; Fisseler-Eckhoff, Annette; Neumann, Jens; Kirchner, Thomas; Buettner, Reinhard; Merkelbach-Bruse, Sabine; Kreipe, Hans; Jonigk, Danny; Jochum, Wolfram; Rodriguez, Regulo; Dietel, Manfred; Horst, David; Hummel, Michael und Laffert, Maximilian von (2021): Status quo of ALK testing in lung cancer: results of an EQA scheme based on in-situ hybridization, immunohistochemistry, and RNA/DNA sequencing. In: Virchows Archiv, Bd. 479, Nr. 2: S. 247-255

Kameritsch, Petra; Singer, Miriam; Nuernbergk, Christoph; Rios, Natalia; Reyes, Anibal M.; Schmidt, Kjestine; Kirsch, Julian; Schneider, Holger; Mueller, Susanna; Pogoda, Kristin; Cui, Ruicen; Kirchner, Thomas; de Wit, Cor; Lange-Sperandio, Baerbel; Pohl, Ulrich; Conrad, Marcus; Radi, Rafael und Beck, Heike (2021): The mitochondrial thioredoxin reductase system (TrxR2) in vascular endothelium controls peroxynitrite levels and tissue integrity. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 118, Nr. 7, e1921828118

Koelsche, Christian; Schrimpf, Daniel; Stichel, Damian; Sill, Martin; Sahm, Felix; Reuss, David E.; Blattner, Mirjam; Worst, Barbara; Heilig, Christoph E.; Beck, Katja; Horak, Peter; Kreutzfeldt, Simon; Paff, Elke; Stark, Sebastian; Johann, Pascal; Selt, Florian; Ecker, Jonas; Sturm, Dominik; Pajtler, Kristian W.; Reinhardt, Annekathrin; Wefers, Annika K.; Sievers, Philipp; Ebrahimi, Azadeh; Suwala, Abigail; Fernandez-Klett, Francisco; Casalini, Belen; Korshunov, Andrey; Hovestadt, Volker; Kommoss, Felix K. F.; Kriegsmann, Mark; Schick, Matthias; Bewerunge-Hudler, Melanie; Milde, Till; Witt, Olaf; Kulozik, Andreas E.; Kool, Marcel; Romero-Perez, Laura; Gruenewald, Thomas G. P.; Kirchner, Thomas; Wick, Wolfgang; Platten, Michael; Unterberg, Andreas; Uhl, Matthias; Abdollahi, Amir; Debus, Jürgen; Lehner, Burkhard; Thomas, Christian; Hasselblatt, Martin; Paulus, Werner; Hartmann, Christian; Staszewski, Ori; Prinz, Marco; Hench, Jürgen; Frank, Stephan; Versleijen-Jonkers, Yvonne M. H.; Weidema, Marije E.; Mentzel, Thomas; Griewank, Klaus; de Alava, Enrique; Martin, Juan Diaz; Gastearena, Miguel A. Idoate; Chang, Kenneth Tou-En; Low, Sharon Yin Yee; Cuevas-Bourdier, Adrian; Mittelbronn, Michel; Mynarek, Martin; Rutkowski, Stefan; Schueller, Ulrich; Mautner, Viktor F.; Schittenhelm, Jens; Serrano, Jonathan; Snuderl, Matija; Buettner, Reinhard; Klingebiel, Thomas; Buslei, Rolf; Gessler, Manfred; Wesseling, Pieter; Dinjens, Winand N. M.; Brandner, Sebastian; Jaunmuktane, Zane; Lyskjaer, Iben; Schirmacher, Peter; Stenzinger, Albrecht; Brors, Benedikt; Glimm, Hanno; Heining, Christoph; Tirado, Oscar M.; Sainz-Jaspeado, Miguel; Mora, Jaume; Alonso, Javier; del Muro, Xavier Garcia; Moran, Sebastian; Esteller, Manel; Benhamida, Jamal K.; Ladanyi, Marc; Wardelmann, Eva; Antonescu, Cristina; Flanagan, Adrienne; Dirksen, Uta; Hohenberger, Peter; Baumhoer, Daniel; Hartmann, Wolfgang; Vokuhl, Christian; Flucke, Uta; Petersen, Iver; Mechtersheimer, Gunhild; Capper, David; Jones, David T. W.; Froehling, Stefan; Pfister, Stefan M. und Deimling, Andreas von (2021): Sarcoma classification by DNA methylation profiling. In: Nature Communications, Bd. 12, Nr. 1, 498

Kumbrink, Jörg; Li, Pan; Pok-Udvari, Agnes; Klauschen, Frederick; Kirchner, Thomas und Jung, Andreas (2021): p130Cas Is Correlated with EREG Expression and a Prognostic Factor Depending on Colorectal Cancer Stage and Localization Reducing FOLFIRI Efficacy. In: International Journal of Molecular Sciences, Bd. 22, Nr. 22, 12364

Li, Jing; Ohmura, Shunya; Marchetto, Aruna; Orth, Martin F.; Imle, Roland; Dallmayer, Marlene; Musa, Julian; Knott, Maximilian M. L.; Holting, Tilman L. B.; Stein, Stefanie; Funk, Cornelius M.; Sastre, Ana; Alonso, Javier; Bestvater, Felix; Kasan, Merve; Romero-Perez, Laura; Hartmann, Wolfgang; Ranft, Andreas; Banito, Ana; Dirksen, Uta; Kirchner, Thomas; Cidre-Aranaz, Florencia und Gruenewald, Thomas G. P. (2021): Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer. In: Nature Communications, Bd. 12, Nr. 1, 5356

Murakami, Masanori; Sun, Na; Greunke, Christian; Feuchtinger, Annette; Kircher, Stefan; Deutschbein, Timo; Papathomas, Thomas; Bechmann, Nicole; Wallace, Paal William; Peitzsch, Mirko; Korpershoek, Esther; Friemel, Juliane; Gimenez-Roqueplo, Anne-Paule; Robledo, Mercedes; Timmers, Henri J. L. M.; Canu, Letizia; Weber, Achim; de Krijger, Ronald R.; Fassnacht, Martin; Knoesel, Thomas; Kirchner, Thomas; Reincke, Martin; Walch, Axel Karl; Kroiss, Matthias und Beuschlein, Felix (2021): Mass spectrometry imaging identifies metabolic patterns associated with malignant potential in pheochromocytoma and paraganglioma. In: European Journal of Endocrinology, Bd. 185, Nr. 1: S. 179-191

Pazos, Montserrat; Eze, Chukwuka; Kahnert, Kathrin; Delius, Maria; Tufman, Amanda; Alba-Alejandre, Irene; Unterrainer, Marcus; Neumann, Jens; Kirchner, Thomas und Manapov, Farkhad (2021): Novel Multimodal Management of Post-Partum Synchronous Metastatic Pulmonary EBV-Associated Lymphoepithelioma-Like Carcinoma (LELC)-A Case Report. In: Diagnostics, Bd. 11, Nr. 11, 2072

Rueschoff, Josef; Baretton, Gustavo; Blaeker, Hendrik; Dietmaier, Wolfgang; Dietel, Manfred; Hartmann, Arndt; Horn, Lars-Christian; Joehrens, Korinna; Kirchner, Thomas; Knuchel, Ruth; Mayr, Doris; Merkelbach-Bruse, Sabine; Schildhaus, Hans-Ulrich; Schirmacher, Peter; Tiemann, Markus; Tiemann, Katharina; Weichert, Wilko und Buettner, Reinhard (2021): MSI-Testung. Was ist neu? Was ist zu beachten? In: Pathologe, Bd. 42, Nr. 4: S. 414-423

Rueschoff, Josef; Baretton, Gustavo; Blaeker, Hendrik; Dietmaier, Wolfgang; Dietel, Manfred; Hartmann, Arndt; Horn, Lars-Christian; Joehrens, Korinna; Kirchner, Thomas; Knuechel, Ruth; Mayr, Doris; Merkelbach-Bruse, Sabine; Schildhaus, Hans-Ulrich; Schirmacher, Peter; Tiemann, Markus; Tiemann, Katharina; Weichert, Wilko und Buettner, Reinhard (2021): MSI testing What's new? What should be considered? In: Pathologe, Bd. 42, Nr. SUPPL 1: S. 110-118

Schulz, Gerald B.; Elezkurtaj, Sefer; Boerding, Teresa; Schmidt, Eva Marina; Elmasry, Manal; Stief, Christian G.; Kirchner, Thomas; Karl, Alexander und Horst, David (2021): Therapeutic and prognostic implications of NOTCH and MAPK signaling in bladder cancer. In: Cancer Science, Bd. 112, Nr. 5: S. 1987-1996 [PDF, 1MB]

Soelch, Susanne; Beaufort, Nathalie; Loessner, Daniela; Kotzsch, Matthias; Reuning, Ute; Luther, Thomas; Kirchner, Thomas und Magdolen, Viktor (2021): Rab31-dependent regulation of transforming growth factor ss expression in breast cancer cells. In: Molecular Medicine, Bd. 27, Nr. 1, 158

Stahler, Arndt; Heinemann, Volker; Schuster, Veronika; Heinrich, Kathrin; Kurreck, Annika; Giessen-Jung, Clemens; Weikersthal, Ludwig Fischer von; Kaiser, Florian; Decker, Thomas; Held, Swantje; Graeven, Ullrich; Schwaner, Ingo; Denzlinger, Claudio; Schenk, Michael; Neumann, Jens; Kirchner, Thomas; Jung, Andreas; Kumbrink, Jorg; Stintzing, Sebastian und Modest, Dominik P. (2021): Consensus molecular subtypes in metastatic colorectal cancer treated with sequential versus combined fluoropyrimidine, bevacizumab and irinotecan (XELAVIRI trial). In: European Journal of Cancer, Bd. 157: S. 71-80

Sultova, Elena; Westphalen, C. Benedikt; Jung, Andreas; Kumbrink, Joerg; Kirchner, Thomas; Mayr, Doris; Rudelius, Martina; Ormanns, Steffen; Heinemann, Volker; Metzeler, Klaus H.; Greif, Philipp A.; Burges, Alexander; Trillsch, Fabian; Mahner, Sven; Harbeck, Nadia und Wuerstlein, Rachel (2021): NGS-guided precision oncology in metastatic breast and gynecological cancer: first experiences at the CCC Munich LMU. In: Archives of gynecology and obstetrics, Bd. 303, Nr. 5: S. 1331-1345 [PDF, 1MB]

Jacob, Sven; Jurinovic, Vindi; Lampert, Christopher; Pretzsch, Elise; Kumbrink, Jörg; Neumann, Jens; Haoyu, Ren; Renz, Bernhard W.; Kirchner, Thomas; Guba, Markus O.; Werner, Jens; Angele, Martin K. und Bösch, Florian (2021): The association of immunosurveillance and distant metastases in colorectal cancer. In: Journal of Cancer Research and Clinical Oncology, Bd. 147, Nr. 11: S. 3333-3341 [PDF, 1MB]

Michl, Marlies; Taverna, F.; Kumbrink, Jörg; Schiergens, Tobias S.; Heinemann, Volker; Engel, Jutta; Kirchner, Thomas und Neumann, Jens (9. Dezember 2020): Biomarker alterations associated with distinct patterns of metastatic spread in colorectal cancer. In: Virchows Archiv, Bd. 478: S. 695-705 [PDF, 1MB]

Albertsmeier, Markus; Altendorf-Hofmann, Annelore; Lindner, Lars H.; Issels, Rolf D.; Kampmann, Eric; Dürr, Hans-Roland; Schubert-Fritschle, Gabriele; Angele, Martin K.; Kirchner, Thomas; Jungbluth, Achim A. und Knösel, Thomas (3. Dezember 2020): Cancer Testis Antigens and Immunotherapy: Expression of PRAME Is Associated with Prognosis in Soft Tissue Sarcoma. In: Cancers, Bd. 12, Nr. 12, 3612 [PDF, 3MB]

Thurmaier, Johannes; Heinemann, Volker; Engel, Jutta; Schubert‐Fritschle, Gabriele; Wiedemann, Max; Nüssler, Natascha C.; Ruppert, Reinhard; Kleeff, Jörg; Schepp, Wolfgang; Löhe, Florian; Karthaus, Meinolf; Neumann, Jens; Kumbrink, Jörg; Taverna, Francesco; Stahler, Arndt

; Heinrich, Kathrin; Westphalen, Christoph Benedikt; Holch, Julian W.; Kirchner, Thomas und Michl, Marlies (28. Oktober 2020): Patients with colorectal cancer and brain metastasis: The relevance of extracranial metastatic patterns predicting time intervals to first occurrence of intracranial metastasis and survival. In: International Journal of Cancer, Bd. 148, Nr. 8: S. 1919-1927 [PDF, 619kB]

Czogalla, Bastian; Pham, Deborah; Trillsch, Fabian; Rottmann, Miriam; Gallwas, Julia; Burges, Alexander; Mahner, Sven; Kirchner, Thomas; Jeschke, Udo; Mayr, Doris und Schmoeckel, Elisa (2020): PD-L1 expression and survival in p16-negative and -positive squamous cell carcinomas of the vulva. In: Journal of Cancer Research and Clinical Oncology, Bd. 146: S. 569-577 [PDF, 1MB]

Issels, Rolf D.; Lindner, Lars H.; Bergwelt-Baildon, Michael von; Lang, Peter; Rischpler, Christoph; Diem, Heinz; Mosetter, Barbara; Eckl, Judith; Schendel, Dolores J.; Salat, Christoph; Stötzer, Oliver; Burdach, Stefan; Luettichau-Teichert, Irene von; Handgretinger, Rupert; Neumann, Jens; Kirchner, Thomas; Steiger, Katja; Boxberg, Melanie; Mansmann, Ulrich; Multhoff, Gabriele und Noessner, Elfriede (2020): Systemic antitumor effect by regional hyperthermia combined with low-dose chemotherapy and immunologic correlates in an adolescent patient with rhabdomyosarcoma - a case report. In: International Journal of Hyperthermia, Bd. 37, Nr. 1: S. 55-65 [PDF, 4MB]

Kruger, Stephan; Schirle, Karoline; Haas, Michael; Crispin, Alexander; Schirra, Jörg; Mayerle, Julia; D'Haese, Jan G.; Kunz, Wolfgang G.; Ricke, Jens; Ormanns, Steffen; Kirchner, Thomas; Kobold, Sebastian; Ilmer, Matthias; Gebauer, Leonie; Westphalen, Christoph B.; Bergwelt-Baildon, Michael von; Werner, Jens; Heinemann, Volker und Boeck, Stefan (2020): Prolonged time to treatment initiation in advanced pancreatic cancer patients has no major effect on treatment outcome: a retrospective cohort study controlled for lead time bias and waiting time paradox. In: Journal of Cancer Research and Clinical Oncology, Bd. 146, Nr. 2: S. 391-399

Gerke, Julia S.; Orth, Martin F.; Tolkach, Yuri; Romero‐Pérez, Laura; Wehweck, Fabienne S.; Stein, Stefanie; Musa, Julian; Knott, Maximilian M.L.; Hölting, Tilman L.B.; Li, Jing; Sannino, Giuseppina; Marchetto, Aruna; Ohmura, Shunya; Cidre‐Aranaz, Florencia; Müller‐Nurasyid, Martina; Strauch, Konstantin; Stief, Christian; Kristiansen, Glen; Kirchner, Thomas; Buchner, Alexander und Grünewald, Thomas G. P. (2020): Integrative clinical transcriptome analysis reveals TMPRSS2‐ERG dependency of prognostic biomarkers in prostate adenocarcinoma. In: International Journal of Cancer, Bd. 146, Nr. 7: S. 2036-2046 [PDF, 10MB]

Müller‐Thomas, Catharina; Heider, Michael; Piontek, Guido; Schlensog, Martin; Bassermann, Florian; Kirchner, Thomas; Germing, Ulrich; Götze, Katharina S. und Rudelius, Martina (2020): Prognostic value of indoleamine 2,3 dioxygenase in patients with higher‐risk myelodysplastic syndromes treated with azacytidine. In: British Journal of Haematology, Bd. 190, Nr. 3: S. 361-370 [PDF, 6MB]

Schinke, Henrik; Heider, Theresa; Herkommer, Timm; Simon, Florian; Soares, Alexandra Blancke; Kranz, Gisela; Samaga, Daniel; Dajka, Laura; Feuchtinger, Annette; Walch, Axel; Valeanu, Laura; Walz, Christoph; Kirchner, Thomas; Canis, Martin; Baumeister, Philipp; Belka, Claus; Maihoefer, Cornelius; Marschner, Sebastian; Pflugradt, Ulrike; Ganswindt, Ute; Hess, Julia; Zitzelsberger, Horst und Gires, Olivier (2020): Digital scoring of EpCAM and slug expression as prognostic markers in head and neck squamous cell carcinomas. In: Molecular Oncology, Bd. 15, Nr. 4: S. 1040-1053 [PDF, 1MB]

Woischke, Christine; Jung, Peter; Jung, Andreas; Kumbrink, Jörg; Eisenlohr, Sibylle; Auernhammer, Christoph Josef; Vieth, Michael; Kirchner, Thomas und Neumann, Jens (2020): Mixed large cell neuroendocrine carcinoma and squamous cell carcinoma of the colon: detailed molecular characterisation of two cases indicates a distinct colorectal cancer entity. In: Journal of Pathology Clinical Research, Bd. 7, Nr. 1: S. 75-85 [PDF, 1MB]

Kirchner, Martina; Glade, Julia; Lehmann, Ulrich; Merkelbach-Bruse, Sabine; Hummel, Michael; Lehmann, Annika; Trautmann, Marcel; Kumbrink, Jorg; Jung, Andreas; Dietmaier, Wolfgang; Endris, Volker; Kazdal, Daniel; Ploeger, Carolin; Evert, Matthias; Horst, David; Kreipe, Hans; Kirchner, Thomas; Wardelmann, Eva; Buettner, Reinhard; Weichert, Wilko; Dietel, Manfred; Schirmacher, Peter; Stenzinger, Albrecht und Pfarr, Nicole (2020): NTRK testing: First results of the QuiP-EQA scheme and a comprehensive map of NTRK fusion variants and their diagnostic coverage by targeted RNA-based NGS assays. In: Genes Chromosomes & Cancer, Bd. 59, Nr. 8: S. 445-453

Orth, Martin F.; Buecklein, Veit Leonhard; Kampmann, Eric; Subklewe, Marion; Noessner, Elfriede; Cidre-Aranaz, Florencia; Romero-Perez, Laura; Wehweck, Fabienne Sophie; Lindner, Lars; Issels, Rolf; Kirchner, Thomas; Altendorf-Hofmann, Annelore; Grunewald, Thomas G. P. und Knösel, Thomas (2020): A comparative view on the expression patterns of PD-L1 and PD-1 in soft tissue sarcomas. In: Cancer Immunology Immunotherapy, Bd. 69, Nr. 7: S. 1353-1362

Kommoss, Felix K. F.; Stichel, Damian; Schrimpf, Daniel; Kriegsmann, Mark; Tessier-Cloutier, Basile; Talhouk, Aline; McAlpine, Jessica N.; Chang, Kenneth T. E.; Sturm, Dominik; Pfister, Stefan M.; Romero-Perez, Laura; Kirchner, Thomas; Grünewald, Thomas G. P.; Buslei, Rolf; Sinn, Hans-Peter; Mechtersheimer, Gunhild; Schirmacher, Peter; Schmidt, Dietmar; Lehr, Hans-Anton; Sahm, Felix; Huntsman, David G.; Gilks, C. Blake; Kommoss, Friedrich; Deimling, Andreas von und Koelsche, Christian (2020): DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnostics. In: Journal of Cancer Research and Clinical Oncology, Bd. 146, Nr. 1: S. 97-104

Stahler, Arndt; Stintzing, Sebastian; Einem, Jobst C. von; Westphalen, Christoph B.; Heinrich, Kathrin; Kraemer, Nicole; Michl, Marlies; Modest, Dominik P.; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Heintges, Tobias; Kahl, Christoph; Kullmann, Frank; Scheithauer, Werner; Moehler, Markus; Kaiser, Florian; Kirchner, Thomas; Jung, Andreas und Heinemann, Volker (2020): Single-nucleotide variants, tumour mutational burden and microsatellite instability in patients with metastatic colorectal cancer: Next-generation sequencing results of the FIRE-3 trial. In: European Journal of Cancer, Bd. 137: S. 250-259

Reichart, Bruno; Langin, Matthias; Radan, Julia; Mokelke, Maren; Buttgereit, Ines; Ying, Jiawei; Fresch, Ann Kathrin; Mayr, Tanja; Issl, Lara; Buchholz, Stefan; Michel, Sebastian; Ellgass, Reinhard; Mihalj, Maks; Egerer, Stefanie; Baehr, Andrea; Kessler, Barbara; Kemter, Elisabeth; Kurome, Mayuko; Zakhartchenko, Valeri; Steen, Stig; Sjoberg, Trygve; Paskevicius, Audrius; Kruger, Luise; Fiebig, Uwe; Denner, Joachim; Godehardt, Antonia W.; Tonjes, Ralf R.; Milusev, Anastasia; Rieben, Robert; Sfriso, Riccardo; Walz, Christoph; Kirchner, Thomas; Ayares, David; Lampe, Karen; Schonmann, Uwe; Hagl, Christian; Wolf, Eckhard; Klymiuk, Nikolai; Abicht, Jan-Michael und Brenner, Paolo (2020): Pig-to-non-human primate heart transplantation: The final step toward clinical xenotransplantation? In: Journal of Heart and Lung Transplantation, Bd. 39, Nr. 8: S. 751-757

Shi, Xiaolong; Kaller, Markus; Rokavec, Matjaz; Kirchner, Thomas; Horst, David und Hermeking, Heiko (2020): Characterization of a p53/miR-34a/CSF1R/STAT3 Feedback Loop in Colorectal Cancer. In: Cellular and Molecular Gastroenterology and Hepatology, Bd. 10, Nr. 2: S. 391-418

Stenzinger, Albrecht; Endris, Volker; Budczies, Jan; Merkelbach-Bruse, Sabine; Kazdal, Daniel; Dietmaier, Wolfgang; Pfarr, Nicole; Siebolts, Udo; Hummel, Michael; Herold, Sylvia; Andreas, Johanna; Zoche, Martin; Toegel, Lars; Rempel, Eugen; Maas, Jörg; Merino, Diana; Stewart, Mark; Zaoui, Karim; Schlesner, Matthias; Glimm, Hanno; Froehling, Stefan; Allen, Jeff; Horst, David; Baretton, Gustavo; Wickenhauser, Claudia; Tiemann, Markus; Evert, Matthias; Moch, Holger; Kirchner, Thomas; Buettner, Reinhard; Schirmacher, Peter; Jung, Andreas; Haller, Florian; Weichert, Wilko und Dietel, Manfred (2020): Harmonization and Standardization of Panel-Based Tumor Mutational Burden Measurement: Real-World Results and Recommendations of the Quality in Pathology Study. In: Journal of Thoracic Oncology, Bd. 15, Nr. 7: S. 1177-1189

Guenther, Michael; Haas, Michael; Heinemann, Volker; Kruger, Stephan; Westphalen, Christoph Benedikt; Bergwelt-Baildon, Michael von; Mayerle, Julia; Werner, Jens; Kirchner, Thomas; Boeck, Stefan und Ormanns, Steffen (2020): Bacterial lipopolysaccharide as negative predictor of gemcitabine efficacy in advanced pancreatic cancer - translational results from the AIO-PK0104 Phase 3 study. In: British Journal of Cancer, Bd. 123, Nr. 9: S. 1370-1376

Heinemann, Volker; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Kaiser, Florian; Al-Batran, Salah-Edin; Heintges, Tobias; Lerchenmüller, Christoph; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Moehler, Markus; Scheithauer, Werner; Held, Swantje; Miller-Phillips, Lisa; Modest, Dominik Paul; Jung, Andreas; Kirchner, Thomas und Stintzing, Sebastian (2020): FOLFIRI plus cetuximab or bevacizumab for advanced colorectal cancer: final survival and per-protocol analysis of FIRE-3, a randomised clinical trial. In: British Journal of Cancer, Bd. 124, Nr. 3: S. 587-594

Marchetto, Aruna; Ohmura, Shunya; Orth, Martin F.; Knott, Maximilian M. L.; Colombo, Maria V.; Arrigoni, Chiara; Bardinet, Victor; Saucier, David; Wehweck, Fabienne S.; Li, Jing; Stein, Stefanie; Gerke, Julia S.; Baldauf, Michaela C.; Musa, Julian; Dallmayer, Marlene; Romero-Perez, Laura; Hoelting, Tilman L. B.; Amatruda, James F.; Cossarizza, Andrea; Henssen, Anton G.; Kirchner, Thomas; Moretti, Matteo; Cidre-Aranaz, Florencia; Sannino, Giuseppina und Grünewald, Thomas G. P. (2020): Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma. In: Nature Communications, Bd. 11, Nr. 1, 2423 [PDF, 2MB]

Mahajan, Ujjwal M.; Goni, Elisabetta; Langhoff, Enno; Li, Qi; Costello, Eithne; Greenhalf, William; Kruger, Stephan; Ormanns, Steffen; Halloran, Christopher; Ganeh, Paula; Marron, Manuela; Laemmerhirt, Felix; Zhao, Yue; Beyer, Georg; Weiss, Frank-Ulrich; Sendler, Matthias; Bruns, Christiane J.; Kohlmann, Thomas; Kirchner, Thomas; Werner, Jens; D'Haese, Jan G.; Bergwelt, Michael von; Heinemann, Volker; Neoptolemos, John P.; Buechler, Markus W.; Belka, Claus; Boeck, Stefan; Lerch, Markus M. und Mayerle, Julia (2020): Cathepsin D Expression and Gemcitabine Resistance in Pancreatic Cancer. In: Jnci Cancer Spectrum, Bd. 4, Nr. 1, pkz060

Schroth, Werner; Buettner, Florian A.; Kandabarau, Siarhei; Hoppe, Reiner; Fritz, Peter; Kumbrink, Jörg; Kirchner, Thomas; Brauer, Heather A.; Ren, Yuqi; Henderson, David; Madden, Stephen F.; Sauer, Georg; Fehm, Tanja; Wallwiener, Diethelm; Fasching, Peter A.; Muerdter, Thomas; Schwab, Matthias und Brauch, Hiltrud (2020): Gene Expression Signatures of BRCAness and Tumor Inflammation Define Subgroups of Early-Stage Hormone Receptor-Positive Breast Cancer Patients. In: Clinical Cancer Research, Bd. 26, Nr. 24: S. 6523-6534

Stahler, Arndt; Stintzing, Sebastian; Modest, Dominik P.; Ricard, Ingrid; Giessen-Jung, Clemens; Kapaun, Christine; Ivanova, Boryana; Kaiser, Florian; Fischer von Weikersthal, Ludwig; Moosmann, Nicolas; Schalhorn, Andreas; Stauch, Martina; Kiani, Alexander; Held, Swantje; Decker, Thomas; Moehler, Markus; Neumann, Jens; Kirchner, Thomas; Jung, Andreas und Heinemann, Volker (2020): Amphiregulin Expression Is a Predictive Biomarker for EGFR Inhibition in Metastatic Colorectal Cancer: Combined Analysis of Three Randomized Trials. In: Clinical Cancer Research, Bd. 26, Nr. 24: S. 6559-6567

Schuettrumpf, Lars; Marschner, Sebastian; Scheu, Katrin; Hess, Julia; Rietzler, Sibylle; Walch, Axel; Baumeister, Philipp; Kirchner, Thomas; Ganswindt, Ute; Zitzelsberger, Horst; Belka, Claus und Maihoefer, Cornelius (2020): Definitive chemoradiotherapy in patients with squamous cell cancers of the head and neck-results from an unselected cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer". In: Radiation Oncology, Bd. 15, Nr. 1, 7

Lin, Shu-Hong; Sampson, Joshua N.; Grünewald, Thomas G. P.; Surdez, Didier; Reynaud, Stephanie; Mirabeau, Olivier; Karlins, Eric; Rubio, Rebeca Alba; Zaidi, Sakina; Grossetete-Lalami, Sandrine; Ballet, Stelly; Lapouble, Eve; Laurence, Valerie; Michon, Jean; Pierron, Gaelle; Kovar, Heinrich; Kontny, Udo; Gonzalez-Neira, Anna; Alonso, Javier; Patino-Garcia, Ana; Corradini, Nadege; Berard, Perrine Marec; Miller, Jeremy; Freedman, Neal D.; Rothman, Nathaniel; Carter, Brian D.; Dagnall, Casey L.; Burdett, Laurie; Jones, Kristine; Manning, Michelle; Wyatt, Kathleen; Zhou, Weiyin; Yeager, Meredith; Cox, David G.; Hoover, Robert N.; Khan, Javed; Armstrong, Gregory T.; Leisenring, Wendy M.; Bhatia, Smita; Robison, Leslie L.; Kulozik, Andreas E.; Kriebel, Jennifer; Meitinger, Thomas; Metzler, Markus; Krumbholz, Manuela; Hartmann, Wolfgang; Strauch, Konstantin; Kirchner, Thomas; Dirksen, Uta; Mirabello, Lisa; Tucker, Margaret A.; Tirode, Franck; Morton, Lindsay M.; Chanock, Stephen J.; Delattre, Olivier und Machiela, Mitchell J. (2020): Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma.
In: PLOS One 15(9), e0237792 [PDF, 1MB]

Ye, Liangtao; Kriegl, Lydia; Reiter, Florian P.; Munker, Stefan M.; Itzel, Timo; Teufel, Andreas; Ziesch, Andreas; Torok, Helga Paula; Kirchner, Thomas; Gerbes, Alexander L.; Guba, Markus; Mayerle, Julia und De Toni, Enrico N. (2020): Prognostic Significance and Functional Relevance of Olfactomedin 4 in Early-Stage Hepatocellular Carcinoma. In: Clinical and Translational Gastroenterology, Bd. 11, e00124

Orth, Martin F.; Hoelting, Tilman L. B.; Dallmayer, Marlene; Wehweck, Fabienne S.; Paul, Tanja; Musa, Julian; Baldauf, Michaela C.; Surdez, Didier; Delattre, Olivier; Knott, Maximilian M. L.; Romero-Perez, Laura; Kasan, Merve; Cidre-Aranaz, Florencia; Gerke, Julia S.; Ohmura, Shunya; Li, Jing; Marchetto, Aruna; Henssen, Anton G.; Oezen, Oezlem; Sugita, Shintaro; Hasegawa, Tadashi; Kanaseki, Takayuki; Bertram, Stefanie; Dirksen, Uta; Hartmann, Wolfgang; Kirchner, Thomas und Grünewald, Thomas G. P. (2020): High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma. In: Cancers, Bd. 12, Nr. 3, 644

Wessely, Anja; Heppt, Markus V.; Kammerbauer, Claudia; Steeb, Theresa; Kirchner, Thomas; Flaig, Michael J.; French, Lars E.; Berking, Carola; Schmoeckel, Elisa und Reinholz, Markus (2020): Evaluation of PD-L1 Expression and HPV Genotyping in Anal Squamous Cell Carcinoma. In: Cancers, Bd. 12, Nr. 9, 2516

Litzka, Christian; Leebmann, Hubert; Wiesinger, Hellmuth; Kirchner, Thomas; Seelbach-Goebel, Birgit und Haeusler, Sebastian Franz Martin (2020): Management Unterbauchraumforderungen in der Schwangerschaft – Fallbeschreibung eines extraovariell-intraabdominalen Dysgerminoms mit Überblick über die Literatur. In: Zeitschrift für Geburtshilfe und Neonatologie, Bd. 224, Nr. 05: S. 306-314

Baumgarten, Louisa von; Kumbrink, Jörg; Jung, Andreas; Reischer, Anna; Flach, Madeleine; Liebmann, Sibylle; Metzeler, Klaus H.; Holch, Julian W.; Niyazi, Maximilian; Thon, Niklas; Straube, Andreas; Bergwelt-Baildon, Michael von; Heinemann, Volker; Kirchner, Thomas und Westphalen, Christoph Benedikt (2020): Therapeutic management of neuro-oncologic patients - potential relevance of CSF liquid biopsy. In: Theranostics, Bd. 10, Nr. 2: S. 856-866

Bösch, Florian; Altendorf-Hofmann, Annelore; Jacob, Sven; Auernhammer, Christoph J.; Spitzweg, Christine; Boeck, Stefan; Schubert-Fritschle, Gabriele; Werner, Jens; Kirchner, Thomas; Angele, Martin K. und Knösel, Thomas (2020): Distinct Expression Patterns of VEGFR 1-3 in Gastroenteropancreatic Neuroendocrine Neoplasms: Supporting Clinical Relevance, but not a Prognostic Factor. In: Journal of Clinical Medicine, Bd. 9, Nr. 10, 3368

Murakami, Masanori; Rhayem, Yara; Kunzke, Thomas; Sun, Na; Feuchtinger, Annette; Ludwig, Philippe; Strom, Tim Matthias; Gomez-Sanchez, Celso; Knösel, Thomas; Kirchner, Thomas; Williams, Tracy Ann; Reincke, Martin; Walch, Axel Karl und Beuschlein, Felix (5. September 2019): In situ metabolomics of aldosterone-producing adenomas. In: JCI Insight, Bd. 4, Nr. 17, e130356 [PDF, 7MB]

Schmoeckel, Elisa; Hofmann, Sophie; Fromberger, Daniel; Rottmann, Miriam; Luthardt, Beate; Burges, Alexander; Jeschke, Udo; Kirchner, Thomas; Lax, Sigurd F. und Mayr, Doris (2019): Comprehensive analysis of PD-L1 expression, HER2 amplification, ALK/EML4 fusion, and mismatch repair deficiency as putative predictive and prognostic factors in ovarian carcinoma. In: Virchows Archiv : an international journal of pathology, Bd. 474, Nr. 5: S. 599-608

Bösch, Florian; Brüwer, Katharina; Altendorf-Hofmann, Annelore; Auernhammer, Christoph J.; Spitzweg, Christine; Westphalen, Benedikt; Boeck, Stefan; Schubert-Fritschle, Gabriele; Werner, Jens; Heinemann, Volker; Kirchner, Thomas; Angele, Martin K. und Knösel, Thomas (2019): Immune checkpoint markers in gastroenteropancreatic neuroendocrine neoplasia. In: Endocrine-Related Cancer, Bd. 26, Nr. 3: S. 293-301

Elmasry, Manal; Brandl, Lydia; Engel, Jutta; Jung, Andreas; Kirchner, Thomas und Horst, David (2019): RBP7 is a clinically prognostic biomarker and linked to tumor invasion and EMT in colon cancer. In: Journal of Cancer, Bd. 10, Nr. 20: S. 4883-4891

Knott, Maximilian M. L.; Hölting, Tilman L. B.; Ohmura, Shunya; Kirchner, Thomas; Cidre-Aranaz, Florencia und Grünewald, Thomas G. P. (2019): Targeting the undruggable: exploiting neomorphic features of fusion oncoproteins in childhood sarcomas for innovative therapies. In: Cancer metastasis reviews, Bd. 38, Nr. 4: S. 625-642 [PDF, 978kB]

Boesch, Florian; Todorova, Rumyana; Link, Helena; Westphalen, C. Benedikt; Böck, Stefan; Heinemann, Volker; Werner, Jens; Kirchner, Thomas; Angele, Martin K. und Neumann, Jens (2019): Molecular subtyping of gastric cancer with respect to the growth pattern of lymph-node metastases. In: Journal of Cancer Research and Clinical Oncology, Bd. 145, Nr. 11: S. 2689-2697

Musa, Julian; Cidre-Aranaz, Florencia; Aynaud, Marie-Ming; Orth, Martin F.; Knott, Maximilian M. L.; Mirabeau, Olivier; Mazor, Gal; Varon, Mor; Hoelting, Tilman L. B.; Grossetete, Sandrine; Gartlgruber, Moritz; Surdez, Didier; Gerke, Julia S.; Ohmura, Shunya; Marchetto, Aruna; Dallmayer, Marlene; Baldauf, Michaela C.; Stein, Stefanie; Sannino, Giuseppina; Li, Jing; Romero-Perez, Laura; Westermann, Frank; Hartmann, Wolfgang; Dirksen, Uta; Gymrek, Melissa; Anderson, Nathaniel D.; Shlien, Adam; Rotblat, Barak; Kirchner, Thomas; Delattre, Olivier und Grünewald, Thomas G. P. (2019): Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes. In: Nature Communications, Bd. 10, 4128 [PDF, 2MB]

Sannino, Giuseppina; Marchetto, Aruna; Ranft, Andreas; Jabar, Susanne; Zacherl, Constanze; Alba-Rubio, Rebeca; Stein, Stefanie; Wehweck, Fabienne S.; Kiran, Merve M.; Hoelting, Tilman L. B.; Musa, Julian; Romero-Perez, Laura; Cidre-Aranaz, Florencia; Knott, Maximilian M. L.; Li, Jing; Jürgens, Heribert; Sastre, Ana; Alonso, Javier; Da Silveira, Willian; Hardiman, Gary; Gerke, Julia S.; Orth, Martin F.; Hartmann, Wolfgang; Kirchner, Thomas; Ohmura, Shunya; Dirksen, Uta und Grünewald, Thomas G. P. (2019): Gene expression and immunohistochemical analyses identify SOX2 as major risk factor for overall survival and relapse in Ewing sarcoma patients. In: Ebiomedicine, Bd. 47: S. 156-162

Spartalis, Christoph; Schmidt, Eva Marina; Elmasry, Manal; Schulz, Gerald Bastian; Kirchner, Thomas und Horst, David (2019): In vivo effects of chemotherapy on oncogenic pathways in colorectal cancer. In: Cancer Science, Bd. 110, Nr. 8: S. 2529-2539

Schulz, Gerald B.; Grimm, Tobias; Sers, Christine; Riemer, Pamela; Elmasry, Manal; Kirchner, Thomas; Stief, Christian G.; Karl, Alexander und Horst, David (2019): Prognostic value and association with epithelial-mesenchymal transition and molecular subtypes of the proteoglycan biglycan in advanced bladder cancer. In: Urologic Oncology-Seminars and Original Investigations, Bd. 37, Nr. 8, 530.e9

Hess, Julia; Unger, Kristian; Maihoefer, Cornelius; Schuettrumpf, Lars; Wintergerst, Ludmila; Heider, Theresa; Weber, Peter; Marschner, Sebastian; Braselmann, Herbert; Samaga, Daniel; Kuger, Sebastian; Pflugradt, Ulrike; Baumeister, Philipp; Walch, Axel; Woischke, Christine; Kirchner, Thomas; Werner, Martin; Werner, Kristin; Baumann, Michael; Budach, Volker; Combs, Stephanie E.; Debus, Jürgen; Grosu, Anca-Ligia; Krause, Mechthild; Linge, Annett; Roedel, Claus; Stuschke, Martin; Zips, Daniel; Zitzelsberger, Horst; Ganswindt, Ute; Henke, Michael und Belka, Claus (2019): A Five-MicroRNA Signature Predicts Survival and Disease Control of Patients with Head and Neck Cancer Negative for HPV Infection. In: Clinical Cancer Research, Bd. 25, Nr. 5: S. 1505-1516

Orth, Martin F.; Gerke, Julia S.; Knoesel, Thomas; Altendorf-Hofmann, Annelore; Musa, Julian; Alba-Rubio, Rebeca; Stein, Stefanie; Hoelting, Tilman L. B.; Cidre-Aranaz, Florencia; Romero-Perez, Laura; Dallmayer, Marlene; Baldauf, Michaela C.; Marchetto, Aruna; Sannino, Giuseppina; Knott, Maximilian M. L.; Wehweck, Fabienne; Ohmura, Shunya; Li, Jing; Hakozaki, Michiyuki; Kirchner, Thomas; Dandekar, Thomas; Butt, Elke und Grünewald, Thomas G. P. (2019): Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma. In: International Journal of Cancer, Bd. 144, Nr. 4: S. 859-867

Dallmayer, Marlene; Li, Jing; Ohmura, Shunya; Rubio, Rebeca Alba; Baldauf, Michaela C.; Hoelting, Tilman L. B.; Musa, Julian; Knott, Max M. L.; Stein, Stefanie; Cidre-Aranaz, Florencia; Wehweck, Fabienne S.; Romero-Perez, Laura; Gerke, Julia S.; Orth, Martin F.; Marchetto, Aruna; Kirchner, Thomas; Bach, Horacio; Sannino, Giuseppina und Grünewald, Thomas G. P. (2019): Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma. In: Cell Death & Disease, Bd. 10, 116

Modest, Dominik Paul; Fischer von Weikersthal, Ludwig; Decker, Thomas; Vehling-Kaiser, Ursula; Uhlig, Jens; Schenk, Michael; Freiberg-Richter, Jens; Peuser, Bettina; Denzlinger, Claudio; Reddemann, Christina Peveling Genannt; Graeven, Ullrich; Schuch, Gunter; Schwaner, Ingo; Stahler, Arndt; Jung, Andreas; Kirchner, Thomas; Held, Swantje; Stintzing, Sebastian; Giessen-Jung, Clemens und Heinemann, Volker (2019): Sequential Versus Combination Therapy of Metastatic Colorectal Cancer Using Fluoropyrimidines, Irinotecan, and Bevacizumab: A Randomized, Controlled StudyXELAVIRI (AIO KRK0110). In: Journal of Clinical Oncology, Bd. 37, Nr. 1

Brandl, Lydia; Hartmann, Daniela; Kirchner, Thomas und Menssen, Antje (2019): Expression of n-MYC, NAMPT and SIRT1 in Basal Cell Carcinomas and their Cells of Origin. In: Acta Dermato-Venereologica, Bd. 99, Nr. 1: S. 63-71

Brandl, Lydia; Kirstein, Nina; Neumann, Jens; Sendelhofert, Andrea; Vieth, Michael; Kirchner, Thomas und Menssen, Antje (2019): The c-MYC/NAMPT/SIRT1 feedback loop is activated in early classical and serrated route colorectal cancer and represents a therapeutic target. In: Medical Oncology, Bd. 36, Nr. 1, 5

Pfarr, Nicole; Kirchner, Martina; Lehmann, Ulrich; Leichsenring, Jonas; Merkelbach-Bruse, Sabine; Glade, Julia; Hummel, Michael; Stoegbauer, Fabian; Lehmann, Annika; Trautmann, Marcel; Kumbrink, Jörg; Jung, Andreas; Dietmaier, Wolfgang; Endris, Volker; Kazdal, Daniel; Evert, Matthias; Horst, David; Kreipe, Hans; Kirchner, Thomas; Wardelmann, Eva; Lassen, Ulrik; Buettner, Reinhard; Weichert, Wilko; Dietel, Manfred; Schirmacher, Peter und Stenzinger, Albrecht (2019): Testing NTRK testing: Wet-lab and in silico comparison of RNA-based targeted sequencing assays. In: Genes Chromosomes & Cancer, Bd. 59, Nr. 3: S. 178-188

Koelsche, Christian; Kriegsmann, Mark; Kommoss, Felix K. F.; Stichel, Damian; Kriegsmann, Katharina; Vokuhl, Christian; Grünewald, Thomas G. P.; Romero-Perez, Laura; Kirchner, Thomas; de Alava, Enrique; Diaz-Martin, Juan; Hartmann, Wolfgang; Baumhoer, Daniel; Antonescu, Cristina R.; Szuhai, Karoly; Flucke, Uta; Dirksen, Uta; Pfister, Stefan M.; Jones, David T. W.; Mechtersheimer, Gunhild und Deimling, Andreas von (2019): DNA methylation profiling distinguishes Ewing-like sarcoma with EWSR1-NFATc2 fusion from Ewing sarcoma. In: Journal of Cancer Research and Clinical Oncology, Bd. 145, Nr. 5: S. 1273-1281

Holch, Julian W.; Ricard, Ingrid; Stintzing, Sebastian; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al-Batran, Salah; Heintges, Tobias; Lerchenmüller, Christian; Kahl, Christoph; Kullmann, Frank; Scheithauer, Werner; Scholz, Michael; Müller, Sebastian; Link, Hartmut; Rost, Andreas; Höffkes, Heinz-Gert; Moehler, Markus; Lindig, Reinhard Udo; Miller-Phillips, Lisa; Kirchner, Thomas; Jung, Andreas; Einem, Jobst C. von; Modest, Dominik Paul und Heinemann, Volker (2018): Relevance of liver-limited disease in metastatic colorectal cancer: Subgroup findings of the FIRE-3/AIO KRK0306 trial. In: International Journal of Cancer, Bd. 142, Nr. 5: S. 1047-1055

Froelich, Matthias F.; Stintzing, Sebastian; Kumbrink, Jörg; Grünewald, Thomas G. P.; Mansmann, Ulrich; Heinemann, Volker; Kirchner, Thomas und Jung, Andreas (2018): The DNA-polymorphism rs849142 is associated with skin toxicity induced by targeted anti-EGFR therapy using cetuximab. In: OncoTarget, Bd. 9, Nr. 54: S. 30279-30288 [PDF, 3MB]

Lamprecht, Sebastian; Kaller, Markus; Schmidt, Eva Marina; Blaj, Cristina; Schiergens, Tobias S.; Engel, Jutta; Jung, Andreas; Hermeking, Heiko; Grünewald, Thomas G. P.; Kirchner, Thomas und Horst, David (2018): PBX3 Is Part of an EMT Regulatory Network and Indicates Poor Outcome in Colorectal Cancer. In: Clinical cancer research, Bd. 24, Nr. 8: S. 1974-1986

Neumann, Jens; Heinemann, Volker; Engel, Jutta; Kirchner, Thomas und Stintzing, Sebastian (2018): The prognostic impact of CDX2 correlates with the underlying mismatch repair status and BRAF mutational status but not with distant metastasis in colorectal cancer. In: Virchows Archiv : an international journal of pathology, Bd. 473, Nr. 2: S. 199-207

Stintzing, Sebastian; Ivanova, Boryana; Ricard, Ingrid; Jung, Andreas; Kirchner, Thomas; Tannapfel, Andrea; Juette, Hendrik; Hegewisch-Becker, Susanna; Arnold, Dirk und Reinacher-Schick, Anke (2018): Amphiregulin (AREG) and Epiregulin (EREG) Gene Expression as Predictor for Overall Survival (OS) in Oxaliplatin/Fluoropyrimidine Plus Bevacizumab Treated mCRC Patients-Analysis of the Phase III AIO KRK-0207 Trial. In: Frontiers in Oncology, Bd. 8, Nr. 474 [PDF, 1MB]

Machiela, Mitchell J.; Grunewald, Thomas G. P.; Surdez, Didier; Reynaud, Stephanie; Mirabeau, Olivier; Karlins, Eric; Rubio, Rebeca Alba; Zaidi, Sakina; Grossetete-Lalami, Sandrine; Ballet, Stelly; Lapouble, Eve; Laurence, Valerie; Michon, Jean; Pierron, Gaelle; Kovar, Heinrich; Gaspar, Nathalie; Kontny, Udo; Gonzalez-Neira, Anna; Picci, Piero; Alonso, Javier; Patino-Garcia, Ana; Corradini, Nadege; Berard, Perrine Marec; Freedman, Neal D.; Rothman, Nathaniel; Dagnall, Casey L.; Burdett, Laurie; Jones, Kristine; Manning, Michelle; Wyatt, Kathleen; Zhou, Weiyin; Yeager, Meredith; Cox, David G.; Hoover, Robert N.; Khan, Javed; Armstrong, Gregory T.; Leisenring, Wendy M.; Bhatia, Smita; Robison, Leslie L.; Kulozik, Andreas E.; Kriebel, Jennifer; Meitinger, Thomas; Metzler, Markus; Hartmann, Wolfgang; Strauch, Konstantin; Kirchner, Thomas; Dirksen, Uta; Morton, Lindsay M.; Mirabello, Lisa; Tucker, Margaret A.; Tirode, Franck; Chanock, Stephen J. und Delattre, Olivier (2018): Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility. In: Nature Communications, Bd. 9, 3184 [PDF, 1MB]

Heublein, Sabine; Albertsmeier, Markus; Pfeifer, David; Löhrs, Lisa; Bazhin, Alexandr V.; Kirchner, Thomas; Werner, Jens; Neumann, Jens und Angele, Martin Kurt (2018): Association of differential miRNA expression with hepatic vs. peritoneal metastatic spread in colorectal cancer. In: BMC Cancer 18:201 [PDF, 1MB]

Oener, Meryem Guelfem; Rokavec, Matjaz; Kaller, Markus; Bouznad, Nassim; Horst, David; Kirchner, Thomas und Hermeking, Heiko (2018): Combined Inactivation of TP53 and MIR34A Promotes Colorectal Cancer Development and Progression in Mice Via Increasing Levels of IL6R and PAI1. In: Gastroenterology, Bd. 155, Nr. 6: S. 1868-1882

Link, Helena; Angele, Martin; Schüller, Miriam; Ganschow, Petra; Machetanz, Lena; Guba, Markus; Werner, Jens; Kirchner, Thomas und Neumann, Jens (2018): Extra-capsular growth of lymph node metastasis correlates with poor prognosis and high SOX9 expression in gastric cancer. In: BMC Cancer 18:483 [PDF, 2MB]

Jung, Andreas und Kirchner, Thomas (2018): Liquid Biopsy in Tumor Genetic Diagnosis. In: Deutsches Ärzteblatt International, Bd. 115, Nr. 10: S. 169-174

Günther, Michael; Veninga, Vivien; Kumbrink, Jörg; Haas, Michael; Westphalen, C. Benedikt; Kruger, Stephan; Heinemann, Volker; Kirchner, Thomas; Böck, Stefan; Jung, Andreas und Ormanns, Steffen (2018): POLE gene hotspot mutations in advanced pancreatic cancer. In: Journal of Cancer Research and Clinical Oncology, Bd. 144, Nr. 11: S. 2161-2166

Li, Jing; Dallmayer, Marlene; Kirchner, Thomas; Musa, Julian und Gruenewald, Thomas G. P. (2018): PRC1: Linking Cytokinesis, Chromosomal Instability, and Cancer Evolution. In: Trends in Cancer, Bd. 4, Nr. 1: S. 59-73

Baldauf, Michaela C.; Orth, Martin F.; Dallmayer, Marlene; Marchetto, Aruna; Gerke, Julia S.; Rubio, Rebeca Alba; Kiran, Merve M.; Musa, Julian; Knott, Maximilian M. L.; Ohmura, Shunya; Li, Jing; Akpolat, Nusret; Akatli, Ayse N.; Ozen, Ozlem; Dirksen, Uta; Hartmann, Wolfgang; Alava, Enrique de; Baumhoer, Daniel; Sannino, Giuseppina; Kirchner, Thomas und Gruenewald, Thomas G. P. (2018): Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets. In: Oncotarget, Bd. 9, Nr. 2: S. 1587-1601

Schmoeckel, Elisa; Kirchner, Thomas und Mayr, Doris (2018): SATB2 is a supportive marker for the differentiation of a primary mucinous tumor of the ovary and an ovarian metastasis of a low-grade appendiceal mucinous neoplasm (LAMN): A series of seven cases. In: Pathology Research and Practice, Bd. 214, Nr. 3: S. 426-430

Hessell, Harald; Poignee-Heger, Manuela; Lohmann, Sabine; Hirscher, Bianca; Herold, Andrea; Assmann, Gerald; Budczies, Jan; Sotlarl, Karl und Kirchner, Thomas (2018): Subtyping Of Triple Negative Breast Carcinoma On The Basis Of RTK Expression. In: Journal of Cancer, Bd. 9, Nr. 15: S. 2589-2602 [PDF, 798kB]

Baldauf, Michaela C.; Gerke, Julia S.; Kirschner, Andreas; Blaeschke, Franziska; Effenberger, Manuel; Schober, Kilian; Rubio, Rebeca Alba; Kanaseki, Takayuki; Kiran, Merve M.; Dallmayer, Marlene; Musa, Julian; Akpolat, Nurset; Akatli, Ayse N.; Rosman, Fernando C.; Ozen, Ozlem; Sugita, Shintaro; Hasegawa, Tadashi; Sugimura, Haruhiko; Baumhoer, Daniel; Knott, Maximilian M. L.; Sannino, Giuseppina; Marchetto, Aruna; Li, Jing; Busch, Dirk H.; Feuchtinger, Tobias; Ohmura, Shunya; Orth, Martin F.; Thiel, Uwe; Kirchner, Thomas und Gruenewald, Thomas G. P. (2018): Systematic identification of cancer-specific MHC-binding peptides with RAVEN. In: Oncoimmunology, Bd. 7, Nr. 9, e1481558

Scheel, Andreas H.; Baenfer, Gudrun; Baretton, Gustavo; Dietel, Manfred; Diezko, Rolf; Henkel, Thomas; Heukamp, Lukas C.; Jasani, Bharat; Joehrens, Korinna; Kirchner, Thomas; Lasitschka, Felix; Petersen, Iver; Reu, Simone; Schildhaus, Hans-Ulrich; Schirmacher, Peter; Schwamborn, Kristina; Sommer, Ulrich; Stoss, Oliver; Tiemann, Markus; Warth, Arne; Weichert, Wilko; Wolf, Jürgen; Büttner, Reinhard und Rueschoff, Josef (2018): Interlaboratory concordance of PD‐L1 immunohistochemistry for non‐small‐cell lung cancer. In: Histopathology, Bd. 72, Nr. 3: S. 449-459

Wintergerst, Ludmila; Selmansberger, Martin; Maihoefer, Cornelius; Schüttrumpf, Lars; Walch, Axel; Wilke, Christina; Pitea, Adriana; Woischke, Christine; Baumeister, Philipp; Kirchner, Thomas; Belka, Claus; Ganswindt, Ute; Zitzelsberger, Horst; Unger, Kristian und Hess, Julia (2018): A prognostic mRNA expression signature of four 16q24.3 genes in radio(chemo)therapy-treated head and neck squamous cell carcinoma (HNSCC). In: Molecular Oncology, Bd. 12, Nr. 12: S. 2085-2101 [PDF, 575kB]

Maihoefer, Cornelius; Schüttrumpf, Lars; Macht, Corinna; Pflugradt, Ulrike; Hess, Julia; Schneider, Ludmila; Woischke, Christine; Walch, Axel; Baumeister, Philipp; Kirchner, Thomas; Zitzelsberger, Horst; Belka, Claus und Ganswindt, Ute (2018): Postoperative (chemo) radiation in patients with squamous cell cancers of the head and neck - clinical results from the cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer". In: Radiation Oncology 13:123 [PDF, 685kB]

Harder, Nathalie; Athelogou, Maria; Hessel, Harald; Brieu, Nicolas; Yigitsoy, Mehmet; Zimmermann, Johannes; Baatz, Martin; Buchner, Alexander; Stief, Christian G.; Kirchner, Thomas; Binnig, Gerd; Schmidt, Guenter und Huss, Ralf (2018): Tissue Phenomics for prognostic biomarker discovery in low- and intermediate-risk prostate cancer. In: Scientific Reports, Bd. 8, 4470 [PDF, 11MB]

Ziegler, Paul K.; Bollrath, Julia; Pallangyo, Charles K.; Matsutani, Takaji; Canli, Oezge; De Oliveira, Tiago; Diamanti, Michaela A.; Müller, Nina; Gamrekelashvili, Jaba; Putoczki, Tracy; Horst, David; Mankan, Arun K.; Oener, Meryem G.; Müller, Susanna; Müller-Hoecker, Josef; Kirchner, Thomas; Slotta-Huspenina, Julia; Taketo, M. Mark; Reinheckel, Thomas; Droese, Stefan; Larner, Andrew C.; Wels, Winfried S.; Ernst, Matthias; Greten, Tim F.; Arkan, Melek C.; Korn, Thomas; Wirth, Dagmar und Greten, Florian R. (2018): Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis. In: Cell, Bd. 174, Nr. 1: S. 88-101

Schmidt, Eva Marina; Lamprecht, Sebastian; Blaj, Cristina; Schaaf, Christian; Krebs, Stefan; Blum, Helmut; Hermeking, Heiko; Jung, Andreas; Kirchner, Thomas und Horst, David (2018): Targeting tumor cell plasticity by combined inhibition of NOT CH and MAPK signaling in colon cancer. In: Journal of Experimental Medicine, Bd. 215, Nr. 6: S. 1693-1708

Stahler, Arndt; Heinemann, Volker; Neumann, Jens; Crispin, Alexander; Schalhorn, Andreas; Stintzing, Sebastian; Giessen-Jung, Clemens; Fischer von Weikersthal, Ludwig; Vehling-Kaiser, Ursula; Stauch, Martina; Quietzsch, Detlef; Holch, Julian W.; Kruger, Stephan; Haas, Michael; Michl, Marlies; Einem, Jobst von; Kirchner, Thomas; Jung, Andreas und Modest, Dominik P. (2017): Prevalence and influence on outcome of HER2/neu, HER3 and NRG1 expression in patients with metastatic colorectal cancer. In: Anti-cancer drugs, Bd. 28, Nr. 7: S. 717-722 [PDF, 422kB]

Heppt, Markus V.; Siepmann, Timo; Engel, Jutta; Schubert-Fritschle, Gabriele; Eckel, Renate; Mirlach, Laura; Kirchner, Thomas; Jung, Andreas; Gesierich, Anja; Ruzicka, Thomas; Flaig, Michael J. und Berking, Carola (2017): Prognostic significance of BRAF and NRAS mutations in melanoma: a German study from routine care. In: BMC Cancer :17:536: S. 1-12 [PDF, 585kB]

Schmoeckel, Elisa; Odai-Afotey, Ashley A.; Schleißheimer, Michael; Rottmann, Miriam; Flesken-Nikitin, Andrea; Ellenson, Lora H.; Kirchner, Thomas; Mayr, Doris und Nikitin, Alexander Yu (2017): LEF1 is preferentially expressed in the tubal-peritoneal junctions and is a reliable marker of tubal intraepithelial lesions. In: Modern Pathology, Bd. 30, Nr. 9: S. 1241-1250

Schubert-Fritschle, Gabriele; Combs, Stephanie E.; Kirchner, Thomas; Nüssler, Volkmar und Engel, Jutta (2017): Use of Multicenter Data in a Large Cancer Registry for Evaluation of Outcome and Implementation of Novel Concepts. In: Frontiers in Oncology: S. 1-13 [PDF, 2MB]

Blaj, Cristina; Bringmann, Agnes; Schmidt, Eva Marina; Urbischek, Manuela; Lamprecht, Sebastian; Fröhlich, Thomas; Arnold, Georg J.; Krebs, Stefan; Blum, Helmut; Hermeking, Heiko; Jung, Andreas; Kirchner, Thomas und Horst, David (2017): ADNP Is a Therapeutically Inducible Repressor of WNT Signaling in Colorectal Cancer. In: Clinical Cancer Research, Bd. 23, Nr. 11: S. 2769-2780

Woischke, Christine; Schaaf, Christian W.; Yang, Hui-Min; Vieth, Michael; Veits, Lothar; Geddert, Helene; Märkl, Bruno; Stömmer, Peter; Schaeffer, David F.; Frölich, Matthias; Blum, Helmut; Vosberg, Sebastian; Greif, Philipp A.; Jung, Andreas; Kirchner, Thomas und Horst, David (2017): In-depth mutational analyses of colorectal neuroendocrine carcinomas with adenoma or adenocarcinoma components. In: Modern Pathology, Bd. 30, Nr. 1: S. 95-103

Holch, Julian Walter; Metzeler, Klaus Hans; Jung, Andreas; Riedmann, Kristina; Jost, Philipp Jakob; Weichert, Wilko; Kirchner, Thomas; Heinemann, Volker und Westphalen, Christoph Benedikt (2017): Universal Genomic Testing: The next step in oncological decision-making or a dead end street? In: European Journal of Cancer, Bd. 82: S. 72-79

Bächmann, Sibylle; Ormanns, Steffen; Haas, Michael; Krüger, Stephan; Remold, Anna; Modest, Dominik Paul; Kirchner, Thomas; Jung, Andreas; Werner, Jens; Heinemann, Volker und Böck, Stefan (2017): Switch in KRAS mutational status during an unusual course of disease in a patient with advanced pancreatic adenocarcinoma: implications for translational research. In: BMC Cancer 17:374 [PDF, 614kB]

Haas, Michael; Ormanns, Steffen; Bächmann, Sibylle; Remold, Anna; Krüger, Stephan; Westphalen, Christoph B.; Siveke, Jens T.; Wenzel, Patrick; Schlitter, Anna Melissa; Esposito, Irene; Quietzsch, Detlef; Clemens, Michael R.; Kettner, Erika; Laubender, Rüdiger P.; Jung, Andreas; Kirchner, Thomas; Böck, Stefan und Heinemann, Volker (2017): Extended RAS analysis and correlation with overall survival in advanced pancreatic cancer. In: British Journal of Cancer, Bd. 116, Nr. 11: S. 1462-1469

Ormanns, Steffen; Haas, Michael; Remold, Anna; Kruger, Stephan; Holdenrieder, Stefan; Kirchner, Thomas; Heinemann, Volker und Boeck, Stefan (2017): The Impact of SMAD4 Loss on Outcome in Patients with Advanced Pancreatic Cancer Treated with Systemic Chemotherapy. In: International Journal of Molecular Sciences, Bd. 18, Nr. 5, 1094 [PDF, 1MB]

Kruger, Stephan; Legenstein, Marie-Louise; Rösgen, Verena; Haas, Michael; Modest, Dominik Paul; Westphalen, Christoph Benedikt; Ormanns, Steffen; Kirchner, Thomas; Heinemann, Volker; Holdenrieder, Stefan und Boeck, Stefan (2017): Serum levels of soluble programmed death protein 1 (sPD-1) and soluble programmed death ligand 1 (sPD-L1) in advanced pancreatic cancer. In: Oncoimmunology, Bd. 6, Nr. 5, e1310358

Lordick, Florian; Al-Batran, Salah-Eddin; Dietel, Manfred; Gaiser, Timo; Hofheinz, Ralf-Dieter; Kirchner, Thomas; Kreipe, Hans H.; Lorenzen, Sylvie; Möhler, Markus; Quaas, Alexander; Röcken, Christoph; Rüschoff, Josef; Tannapfel, Andrea; Thuss-Patience, Peter und Baretton, Gustavo (2017): HER2 testing in gastric cancer: results of a German expert meeting. In: Journal of Cancer Research and Clinical Oncology, Bd. 143, Nr. 5: S. 835-841

Blaj, Cristina; Schmidt, Eva Marina; Lamprecht, Sebastian; Hermeking, Heiko; Jung, Andreas; Kirchner, Thomas und Horst, David (2017): Oncogenic Effects of High MAPK Activity in Colorectal Cancer Mark Progenitor Cells and Persist Irrespective of RAS Mutations. In: Cancer Research, Bd. 77, Nr. 7: S. 1763-1774

Lamprecht, Sebastian; Schmidt, Eva Marina; Blaj, Cristina; Hermeking, Heiko; Jung, Andreas; Kirchner, Thomas und Horst, David (2017): Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer. In: Nature Communications, Bd. 8, 1406 [PDF, 4MB]

Sannino, Giuseppina; Marchetto, Aruna; Kirchner, Thomas und Grünewald, Thomas G. P. (2017): Epithelial-to-Mesenchymal and Mesenchymal-to-Epithelial Transition in Mesenchymal Tumors: A Paradox in Sarcomas? In: Cancer Research, Bd. 77, Nr. 17: S. 4556-4561

Perez-Rivas, Luis G.; Osswald, Andrea; Knösel, Thomas; Lucia, Kristin; Schaaf, Christian; Hristov, Michael; Fazel, Julia; Kirchner, Thomas; Beuschlein, Felix; Reincke, Martin und Theodoropoulou, Marily (2017): Expression and mutational status of USP8 in tumors causing ectopic ACTH secretion syndrome. In: Endocrine-Related Cancer, Bd. 24, Nr. 9: L73-L77

Modest, Dominik P.; Stintzing, Sebastian; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al-Batran, Salah-Eddin; Heintges, Tobias; Lerchenmüller, Christian; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Scheithauer, Werner; Kirchner, Thomas; Jung, Andreas; Stauch, Martina; Einem, Jobst Christian von; Möhler, Markus; Held, Swantje und Heinemann, Volker (2017): Relation of early tumor shrinkage (ETS) observed in first-line treatment to efficacy parameters of subsequent treatment in FIRE-3 (AIOKRK0306). In: International Journal of Cancer, Bd. 140, Nr. 8: S. 1918-1925

Thasler, Reinhard M. K.; Berghammer, Andreas J.; Kirchner, Thomas; Slotta-Huspenina, Julia; Becker, Karl-Friedrich; Schiergens, Tobias; Thasler, Wolfgang E. und Wichmann, Heinz Erich (2017): Federated Biobanking with Corporate Service Unit: The Munich Biobank Alliance Blueprint. In: Biopreservation and Biobanking, Bd. 15, Nr. 1: S. 75-79

Müller, Karin A. L.; Heinzmann, David; Klingel, Karin; Fallier-Becker, Petra; Kandolf, Reinhard; Kilias, Antonios; Walker-Allgaier, Britta; Borst, Oliver; Kumbrink, Jörg; Kirchner, Thomas; Langer, Harald; Geisler, Tobias; Schreieck, Jürgen; Gramlich, Michael; Gawaz, Meinrad und Seizer, Peter (2017): Histopathological and Immunological Characteristics of Tachycardia-Induced Cardiomyopathy. In: Journal of the American College of Cardiology, Bd. 69, Nr. 17: S. 2160-2172

Kirschner, Andreas; Thiede, Melanie; Grünewald, Thomas G. P.; Rubio, Rebeca Alba; Richter, Günther H. S.; Kirchner, Thomas; Busch, Dirk H.; Burdach, Stefan und Thiel, Uwe (2017): Pappalysin-1 T cell receptor transgenic allo-restricted T cells kill Ewing sarcoma in vitro and in vivo. In: Oncoimmunology, Bd. 6, Nr. 2, e1273301

Stintzing, Sebastian; Modest, Dominik Paul; Jung, Andreas; Kirchner, Thomas; Schäfer, Reinhold; Sers, Christine; Hildebrandt, Bert; Daum, Severin; Folprecht, Gunnar; Schuler, Martin H.; Kasper, Stefan; Trojan, Jorg; Jaeger, Dirk; Schulze-Bergkamen, Henning; Fischer von Weikersthal, Ludwig; Schalhorn, Alexander und Heinemann, Volker (2016): Differences in gene-expression in mCRC tissue samples with regard to tumor location and used chemotherapeutic substances: Data of the FIRE-1 study. In: Journal of Clinical Oncology, Bd. 34, Nr. 4

Modest, Dominik Paul; Stintzing, Sebastian; Fischer von Weikersthal, Ludwig; Sobrero, Alberto F.; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al-Batran, Salah-Eddin; Heintges, Tobias; Seipelt, Gernot; Lerchenmüller, Christian A.; Kahl, Christoph; Kullmann, Frank; Stauch, Martina; Scheithauer, Werner; Held, Swantje; Moehler, Markus H.; Jung, Andreas; Kirchner, Thomas und Heinemann, Volker (2016): Time-course evaluation of survival and treatment in FIRE-3 (AIO KRK0306, first-line therapy of KRAS wild-type metastatic colorectal cancer with FOLFIRI plus cetuximab or bevacizumab). In: Journal of Clinical Oncology, Bd. 34, Nr. 4

Kruger, Stephan; Haas, Michael; Burger, Philipp Johannes; Ormanns, Steffen; Modest, Dominik Paul; Westphalen, Christoph Benedikt; Michl, Marlies; Kleespies, Axel; Angele, Martin Kurt; Hartwig, Werner; Bruns, Christiane Josephine; Niyazi, Maximilian; Roeder, Falk; Kirchner, Thomas; Werner, Jens; Heinemann, Volker und Boeck, Stefan (2016): Isolated pulmonary metastases define a favorable subgroup in metastatic pancreatic cancer. In: Pancreatology, Bd. 16, Nr. 4: S. 593-598

Sannino, Giuseppina; Pasqualini, Lorenza; Ricciardelli, Eugenia; Montilla, Patricia; Soverchia, Laura; Ruggeri, Barbara; Falcinelli, Silvia; Renzi, Alessandra; Ludka, Colleen; Kirchner, Thomas; Grünewald, Thomas G. P.; Ciccocioppo, Roberto; Ubaldi, Massimo und Hardiman, Gary (2016): Acute stress enhances the expression of neuroprotection- and neurogenesis-associated genes in the hippocampus of a mouse restraint model. In: Oncotarget, Bd. 7, Nr. 8: S. 8455-8465

Stintzing, Sebastian; Modest, Dominik P.; Rossius, Lisa; Lerch, Markus M.; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al-Batran, Salah-Eddin; Heintges, Tobias; Lerchenmüller, Christian; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Stauch, Martina; Scheithauer, Werner; Held, Swantje; Giessen-Jung, Clemens; Moehler, Markus; Jagenburg, Andreas; Kirchner, Thomas; Jung, Andreas und Heinemann, Volker (2016): FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab for metastatic colorectal cancer (FIRE-3): a post-hoc analysis of tumour dynamics in the final RAS wild-type subgroup of this randomised open-label phase 3 trial. In: Lancet Oncology, Bd. 17, Nr. 10: S. 1426-1434

Kirsch, Julian; Schneider, Holger; Pagel, Judith-Irina; Rehberg, Markus; Singer, Miriam; Hellfritsch, Juliane; Chillo, Omary; Schubert, Kai Michael; Qiu, Jiehua; Pogoda, Kristin; Kameritsch, Petra; Uhl, Bernd; Pircher, Joachim; Deindl, Elisabeth; Müller, Susanna; Kirchner, Thomas; Pohl, Ulrich; Conrad, Marcus und Beck, Heike (2016): Endothelial Dysfunction, and A Prothrombotic, Proinflammatory Phenotype Is Caused by Loss of Mitochondrial Thioredoxin Reductase in Endothelium. In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 36, Nr. 9: S. 1891-1899

Blaeschke, Franziska; Thiel, Uwe; Kirschner, Andreas; Thiede, Melanie; Rubio, Rebeca Alba; Schirmer, David; Kirchner, Thomas; Richter, Günther H. S.; Mall, Sabine; Klar, Richard; Riddell, Stanley; Busch, Dirk H.; Krackhardt, Angela; Grunewald, Thomas G. P. und Burdach, Stefan (2016): Human HLA-A*02:01/CHM1(+) allo-restricted T cell receptor transgenic CD8(+) T Cells specifically inhibit Ewing sarcoma growth in vitro and in vivo. In: Oncotarget, Bd. 7, Nr. 28: S. 43267-43280

Endris, Volker; Stenzinger, Albrecht; Pfarr, Nicole; Penzel, Roland; Möbs, Markus; Lenze, Dido; Darb-Esfahani, Silvia; Hummel, Michael; Merkelbach-Bruse, Sabine; Jung, Andreas; Lehmann, Ulrich; Kreipe, Hans; Kirchner, Thomas; Büttner, Reinhard; Jochum, Wolfram; Höfler, Gerald; Dietel, Manfred; Weichert, Wilko und Schirmacher, Peter (2016): NGS-based BRCA1/2 mutation testing of high-grade serous ovarian cancer tissue: results and conclusions of the first international round robin trial. In: Virchows Archiv, Bd. 468, Nr. 6: S. 697-705

Kruger, Stephan; Haas, Michael; Burger, Philipp Johannes; Ormanns, Steffen; Modest, Dominik Paul; Westphalen, Christoph Benedikt; Kleespies, Axel; Angele, Martin Kurt; Hartwig, Werner; Bruns, Christiane Josephine; Kirchner, Thomas; Werner, Jens; Heinemann, Volker und Boeck, Stefan (2016): Acinar cell carcinoma of the pancreas: a rare disease with different diagnostic and therapeutic implications than ductal adenocarcinoma. In: Journal of Cancer Research and Clinical Oncology, Bd. 142, Nr. 12: S. 2585-2591

Ormanns, Steffen; Haas, Michael; Baechmann, Sibylle; Altendorf-Hofmann, Annelore; Remold, Anna; Quietzsch, Detlef; Clemens, Michael R.; Bentz, Martin; Geissler, Michael; Lambertz, Helmut; Kruger, Stephan; Kirchner, Thomas; Heinemann, Volker und Boeck, Stefan (2016): Impact of SPARC expression on outcome in patients with advanced pancreatic cancer not receiving nab-paclitaxel: a pooled analysis from prospective clinical and translational trials. In: British Journal of Cancer, Bd. 115, Nr. 12: S. 1520-1529

Scheel, Andreas H.; Dietel, Manfred; Heukamp, Lukas C.; Jöhrens, Korinna; Kirchner, Thomas; Reu, Simone; Rüschoff, Josef; Schildhaus, Hans-Ulrich; Schirmacher, Peter; Tiemann, Markus; Warth, Arne; Weichert, Wilko; Fischer, Rieke N.; Wolf, Jürgen und Buettner, Reinhard (2016): Harmonized PD-L1 immunohistochemistry for pulmonary squamous-cell and adenocarcinomas. In: Modern Pathology, Bd. 29, Nr. 10: S. 1165-1172

Fendler, Wolfgang P.; Schmidt, Dorothea F.; Wenter, Vera; Thierfelder, Kolja M.; Zach, Christian; Stief, Christian; Bartenstein, Peter; Kirchner, Thomas; Gildehaus, Franz J.; Gratzke, Christian und Faber, Claudius (2016): ⁶⁸Ga-PSMA PET/CT Detects the Location and Extent of Primary Prostate Cancer. In: Journal of Nuclear Medicine, Bd. 57, Nr. 11: S. 1720-1725

Schachschal, Guido; Sehner, Susanne; Choschzick, Matthias; Aust, Daniela; Brandl, Lydia; Vieth, Michael; Wegscheider, Karl; Baretton, Gustavo B.; Kirchner, Thomas; Sauter, Guido und Rösch, Thomas (2016): Impact of reassessment of colonic hyperplastic polyps by expert GI pathologists. In: International Journal of Colorectal Disease, Bd. 31, Nr. 3: S. 675-683

Ormanns, Steffen; Siveke, Jens T.; Heinemann, Volker; Haas, Michael; Sipos, Bence; Schlitter, Anna Melissa; Esposito, Irene; Jung, Andreas; Laubender, Rüdiger P.; Kruger, Stephan; Vehling-Kaiser, Ursula; Winkelmann, Cornelia; Fischer von Weikersthal, Ludwig; Clemens, Michael R.; Gauler, Thomas C.; Märten, Angela; Geissler, Michael; Greten, Tim F.; Kirchner, Thomas und Boeck, Stefan (2014): pERK, pAKT and p53 as tissue biomarkers in erlotinib-treated patients with advanced pancreatic cancer: a translational subgroup analysis from AIO-PK0104. In: BMC Cancer 14:624 [PDF, 408kB]

Hermans, Cecilia; Anz, David; Engel, Jutta; Kirchner, Thomas; Endres, Stefan und Mayr, Doris (2014): Analysis of FoxP3+T-Regulatory Cells and CD8+T-Cells in Ovarian Carcinoma: Location and Tumor Infiltration Patterns Are Key Prognostic Markers.
In: PLOS ONE 9(11), e111757 [PDF, 2MB]

Cernat, Laura; Blaj, Cristina; Jackstadt, Rene; Brandl, Lydia; Engel, Jutta; Hermeking, Heiko; Jung, Andreas; Kirchner, Thomas und Horst, David (2014): Colorectal Cancers Mimic Structural Organization of Normal Colonic Crypts.
In: PLOS ONE 9(8), e104284 [PDF, 24MB]

Göktuna, Serkan I.; Canli, Ozge; Bollrath, Julia; Fingerle, Alexander A.; Horst, David; Diamanti, Michaela A.; Pallangyo, Charles; Bennecke, Moritz; Nebelsiek, Tim; Mankan, Arun K.; Lang, Roland; Artis, David; Hu, Yinling; Patzelt, Thomas; Ruland, Jürgen; Kirchner, Thomas; Taketo, M. Mark; Chariot, Alain; Arkan, Melek C. und Greten, Florian R. (2014): IKKα Promotes Intestinal Tumorigenesis by Limiting Recruitment of M1-like Polarized Myeloid Cells. In: Cell Reports, Bd. 7, Nr. 6: S. 1914-1925 [PDF, 3MB]

Zeindl-Eberhart, Evelyn; Brandl, Lydia; Liebmann, Sibylle; Ormanns, Steffen; Scheel, Silvio K.; Brabletz, Thomas; Kirchner, Thomas und Jung, Andreas (2014): Epithelial-Mesenchymal Transition Induces Endoplasmic-Reticulum-Stress Response in Human Colorectal Tumor Cells.
In: PLOS ONE 9(1), e87386 [PDF, 823kB]

Knösel, Thomas; Altendorf-Hofmann, Annelore; Lindner, Lars H.; Issels, Rolf; Hermeking, Heiko; Schuebbe, Gesa; Gibis, Sebastian; Siemens, Helge; Kampmann, Eric und Kirchner, Thomas (2014): Loss of p16(INK4a) is associated with reduced patient survival in soft tissue tumours, and indicates a senescence barrier. In: Journal of clinical pathology, Bd. 67, Nr. 7: S. 592-598 [PDF, 1MB]

Albrecht, Heinz; Hagel, Alexander; De Rossi, Thomas; Rau, Tilman T.; Kirchner, Thomas; Neurath, Markus F. und Raithel, Martin (2014): Brown bowel syndrome: A rare complication in diseases associated with long-standing malabsorption. In: Digestion, Bd. 89, Nr. 2: S. 105-109 [PDF, 142kB]

Hitkova, Ivana; Yuan, Gang; Anderl, Florian; Gerhard, Markus; Kirchner, Thomas; Reu, Simone; Röcken, Christoph; Schäfer, Claus; Schmid, Roland M.; Vogelmann, Roger; Ebert, Matthias P. A. und Burgermeister, Elke (April 2013): Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis.
In: PLOS Pathogens 9(4), e1003251 [PDF, 1MB]

Gallmeier, Eike; Bader, Dominik C.; Kriegl, Lydia; Berezowska, Sabina; Seeliger, Hendrik; Göke, Burkhard; Kirchner, Thomas; Bruns, Christiane und De Toni, Enrico N. (2013): Loss of TRAIL-receptors is a recurrent feature in pancreatic cancer and determines the prognosis of patients with no nodal metastasis after surgery.
In: PLOS ONE 8(2), e56760 [PDF, 785kB]

Heublein, Sabine; Grasse, Katinka; Hessel, Harald; Burges, Alexander; Lenhard, Miriam; Engel, Jutta; Kirchner, Thomas; Jeschke, Udo und Mayr, Doris (2013): KRAS, BRAF genotyping reveals genetic heterogeneity of ovarian borderline tumors and associated implants. In: BMC Cancer 13:483 [PDF, 1MB]

Giessen, Clemens; Di Gioia, Dorit; Huber, Bruno; Seppi, Bettina; Graser, Anno; Duerr, Hans Roland; Mayr, Doris; Kirchner, Thomas; Rosenwald, Andreas; Forstpointner, Roswitha; Heinemann, Volker; Bogner, Johannes R. und Ostermann, Helmut (Februar 2012): Primary effusion lymphoma (PEL) without effusion: a patient case report of a PEL solid variant. In: Journal of clinical pathology, Bd. 65, Nr. 2: S. 189-90 [PDF, 530kB]

Kriegl, Lydia; Jung, Andreas; Horst, David; Rizzani, Antonia; Jackstadt, Rene; Hermeking, Heiko; Gallmeier, Eike; Gerbes, Alexander L.; Kirchner, Thomas; Göke, Burkhard und De Toni, Enrico N. (2012): Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer.
In: PLOS ONE 7(12), e51654 [PDF, 646kB]

Modest, Dominik P.; Brodowicz, Thomas; Stintzing, Sebastian; Jung, Andreas; Neumann, Jens; Laubender, Ruediger P.; Ocvirk, Janja; Kurteva, Galina; Papai, Zsuzsanna; Knittelfelder, Regina; Kirchner, Thomas; Heinemann, Volker und Zielinski, Christoph C. (2012): Impact of the Specific Mutation in KRAS Codon 12 Mutated Tumors on Treatment Efficacy in Patients with Metastatic Colorectal Cancer Receiving Cetuximab-Based First-Line Therapy: A Pooled Analysis of Three Trials. In: Oncology, Nr. 5: S. 241-247 [PDF, 200kB]

Neumann, Jens; Bahr, Fiorina; Horst, David; Kriegl, Lydia; Engel, Jutta; Luque, Raquel Mejias; Gerhard, Markus; Kirchner, Thomas und Jung, Andreas (2011): SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancer. In: BMC Cancer 11:518 [PDF, 4MB]

Reinacher-Schick, Anke; Arnold, Dirk; Trarbach, Tanja; Ridwelski, Karsten; Bruch, Hans-Peter; Kirchner, Thomas; Kubicka, Stefan und Schmoll, Hans-Joachim (2010): Adjuvante Therapie des Kolonkarzinoms. In: Onkologie, Nr. 4: S. 2-7 [PDF, 293kB]

Arnold, Dirk; Schmoll, Hans-Joachim; Lang, Hauke; Knoefel, Wolfram Trudo; Ridwelski, Karsten; Trarbach, Tanja; Staib, Ludger; Kirchner, Thomas; Geissler, Michael; Seufferlein, Thomas; Amthauer, Holger; Riess, Hanno; Schlitt, Hans J. und Piso, Pompiliu (2010): Spezielle Therapiesituationen beim metastasierten kolorektalen Karzinom. In: Onkologie, Nr. 4: S. 8-18 [PDF, 785kB]

Kriegl, Lydia; Horst, David; Reiche, Jana A.; Engel, Jutta; Kirchner, Thomas und Jung, Andreas (2010): LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer. In: Journal of Translational Medicine 8:123 [PDF, 1MB]

Scheel, Silvio K.; Porzner, Marc; Pfeiffer, Sabine; Ormanns, Steffen; Kirchner, Thomas und Jung, Andreas (2010): Mutations in the WTX - gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancers. In: BMC Cancer 10:413 [PDF, 701kB]

Arnold, Dirk; Rummeny, Ernst J.; Kirchner, Thomas; Ridwelski, Karsten; Oettle, Helmut; Hartmann, Jörg Thomas; Moehler, Markus; Hölscher, Arnulf; Lang, Hauke; Schlitt, Hans J. und Neuhaus, Peter (2009): Diagnostik und Therapie von Lebermetastasen bei kolorektalem Primärtumor. In: Onkologie, Nr. 2: S. 7-12 [PDF, 252kB]

Mayr, Doris; Heim, Sibylle; Weyrauch, Kerstin; Zeindl-Eberhart, Evelyn; Kunz, Anne; Engel, Jutta und Kirchner, Thomas (2009): Chromogenic in situ hybridization for Her-2/neu-oncogene in breast cancer: Comparison of a new dual-colour chromogenic in situ hybridization with immunohistochemistry and fluorescence in situ hybridization. In: Histopathology, Bd. 55, Nr. 6: S. 716-723

Zeitungsartikel

Kirchner, Thomas (6. Mai 2020): Pathologe über Covid-19-Tote: "Virus verkleistert Lungenbläschen wie eine Tapete". In: Focus online

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