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Eine Ebene höherGruppiert nach: Dokumententyp |
Veröffentlichungsdatum
Anzahl der Publikationen: 17
2021
Pavlou, Marina; Schön, Christian; Occelli, Laurence M.; Rossi, Axel; Meumann, Nadja; Boyd, Ryan F.; Bartoe, Joshua T.; Siedlecki, Jakob; Gerhardt, Maximilian J.; Babutzka, Sabrina; Bogedein, Jacqueline; Wagner, Johanna E.; Priglinger, Siegfried G.; Biel, Martin; Petersen-Jones, Simon M.; Büning, Hildegard und Michalakis, Stylianos
(2021):
Novel AAV capsids for intravitreal gene therapy of photoreceptor disorders.
In: EMBO Molecular Medicine, Bd. 13, Nr. 4, e13392
[PDF, 4MB]
2019
Tobias, Peters; Philipp, Seitz Immanuel; Stylianos, Michalakis; Martin, Biel; Barbara, Wilhelm; Felix, Reichel; Alexander, Ochakovski Guy; Eberhart, Zrenner; Marius, Ueffing; Birgit, Korbmacher; Sven, Korte; Ulrich, Bartz-Schmidt Karl; Dominik, Fischer Manuel; Bartz-Schmidt, Karl Ulrich; Bolz, Sylvia; Fischer, Dominik; Kohl, Susanne; Kuehlewein, Laura; Muehlfriedel, Regine; Neubauer, Jonas; Ochakovski, Alex; Paquet-Durand, Francois; Seeliger, Mathias; Sothilingam, Vithiyanjali; Ueffing, Marius; Weisschuh, Nicole; Wissinger, Bernd; Zhour, Ahmad; Zobor, Ditta; Zrenner, Eberhart; Biel, Martin; Michalakis, Stylianos; Schön, Christian; Kahle, Nadine; Peters, Tobias; Wilhelm, Barbara; Tsang, Steven und Gloeckner, Christian Johannes
(2019):
Safety and Toxicology of Ocular Gene Therapy with Recombinant AAV Vector rAAV.hCNGA3 in Nonhuman Primates.
In: Human Gene Therapy Clinical Development, Bd. 30, Nr. 2: S. 50-56
Alexa, Patrick; Oligschleger, Christina; Gröger, Pascal; Morchutt, Claudius; Vyas, Vijay S.; Lotsch, Bettina V.; Schön, Christian; Gutzler, Rico und Kern, Klaus
(2019):
Short‐Range Structural Correlations in Amorphous 2D Polymers.
In: ChemPhysChem, Bd. 20, Nr. 18: S. 2340-2347
[PDF, 1MB]
2018
Petersen-Jones, Simon M.; Occelli, Laurence M.; Winkler, Paige A.; Lee, Winston; Sparrow, Janet R.; Tsukikawa, Mai; Boye, Sanford L.; Chiodo, Vince; Capasso, Jenina E.; Becirovic, Elvir; Schön, Christian; Seeliger, Mathias W.; Levin, Alex V.; Michalakis, Stylianos; Hauswirth, William W. und Tsang, Stephen H.
(2018):
Patients and animal models of CNG beta 1-deficient retinitis pigmentosa support gene augmentation approach.
In: Journal of Clinical Investigation, Bd. 128, Nr. 1: S. 190-206
[PDF, 23MB]
Blank, Thomas; Goldmann, Tobias; Koch, Mirja; Amann, Lukas; Schön, Christian; Bonin, Michael; Pang, Shengru; Prinz, Marco; Burnet, Michael; Wagner, Johanna E.; Biel, Martin und Michalakis, Stylianos
(2018):
Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa.
In: Frontiers in Immunology, Bd. 8, 1930
[PDF, 7MB]
2017
Böhm, Sybille; Riedmayr, Lisa M.; Nguyen, O. N. Phuong; Giessl, Andreas; Liebscher, Toni; Butz, Elisabeth S.; Schön, Christian; Michalakis, Stylianos; Wahl-Schott, Christian; Biel, Martin und Becirovic, Elvir
(2017):
Peripherin-2 and Rom-1 have opposing effects on rod outer segment targeting of retinitis pigmentosa-linked peripherin-2 mutants.
In: Scientific Reports, Bd. 7, 2321
[PDF, 3MB]
Michalakis, Stylianos; Schön, Christian; Becirovic, Elvir und Biel, Martin
(2017):
Gene therapy for achromatopsia.
In: Journal of Gene Medicine, Bd. 19, Nr. 3, e2944
Mühlfriedel, Regine; Tanimoto, Naoyuki; Schön, Christian; Sothilingam, Vithiyanjali; Garrido, Marina Garcia; Beck, Susanne C.; Huber, Gesine; Biel, Martin; Seeliger, Mathias W. und Michalakis, Stylianos
(2017):
AAV-Mediated Gene Supplementation Therapy in Achromatopsia Type 2: Preclinical Data on Therapeutic Time Window and Long-Term Effects.
In: Frontiers in Neuroscience, Bd. 11, 292
[PDF, 5MB]
Michalakis, Stylianos; Fischer, M. Dominik; Schön, Christian; Wilhelm, Barbara; Zobor, Ditta; Muhlfriedel, Regine; Sothilingam, Vithiyanjali; Kohl, Susanne; Peters, Tobias; Zrenner, Eberhart; Bartz-Schmidt, Karl Ulrich; Üffing, Marius; Wissinger, Bernd; Seeliger, Mathias und Biel, Martin
(2017):
Gene Supplementation Therapy for CNGA3-Linked Achromatopsia.
In: Molecular therapy, Bd. 25, Nr. 5: S. 354
Occelli, Laurence M.; Schön, Christian; Seeliger, Mathias W.; Biel, Martin; Michalakis, Stylianos und Petersen-Jones, Simon M.
(2017):
Gene Supplementation Rescues Rod Function and Preserves Photoreceptor and Retinal Morphology in Dogs, Leading the Way Toward Treating Human PDE6A-Retinitis Pigmentosa.
In: Human Gene therapy, Bd. 28, Nr. 12: S. 1189-1201
Schön, Christian; Sothilingam, Vithiyanjali; Mühlfriedel, Regine; Garrido, Marina Garcia; Beck, Susanne C.; Tanimoto, Naoyuki; Wissinger, Bernd; Paquet-Durand, Francois; Biel, Martin; Michalakis, Stylianos und Seeliger, Mathias W.
(2017):
Gene Therapy Successfully Delays Degeneration in a Mouse Model of PDE6A-Linked Retinitis Pigmentosa (RP43).
In: Human Gene therapy, Bd. 28, Nr. 12: S. 1180-1188
Laprell, Laura; Tochitsky, Ivan; Kaur, Kuldeep; Manookin, Michael B.; Stein, Marco; Barber, David M.; Schön, Christian; Michalakis, Stylianos; Biel, Martin; Kramer, Richard H.; Sumser, Martin P.; Trauner, Dirk und Gelder, Russell N. van
(2017):
Photopharmacological control of bipolar cells restores visual function in blind mice.
In: Journal of Clinical investigation, Bd. 127, Nr. 7: S. 2598-2611
Herms, Jochen und Schön, Christian
(2017):
In vivo imaging of retinal neurodegeneration at the single cell level in humans.
In: Brain, Bd. 140: S. 1542-1543
2016
Schön, Christian; Asteriti, Sabrina; Koch, Susanne; Sothilingam, Vithiyanjali; Garrido, Marina Garcia; Tanimoto, Naoyuki; Herms, Jochen; Seeliger, Mathias W.; Cangiano, Lorenzo; Biel, Martin und Michalakis, Stylianos
(2016):
Loss of HCN1 enhances disease progression in mouse models of CNG channel-linked retinitis pigmentosa and achromatopsia.
In: Human Molecular Genetics, Bd. 25, Nr. 6: S. 1165-1175
Schön, Christian; Paquet-Durand, Francois und Michalakis, Stylianos
(2016):
Ca(v)1.4 L-Type Calcium Channels Contribute to Calpain Activation in Degenerating Photoreceptors of rd1 Mice.
In: PLOS ONE 11(6), e0156974 [PDF, 1MB]
In: PLOS ONE 11(6), e0156974 [PDF, 1MB]
Becirovic, Elvir; Böhm, Sybille; Nguyen, Ong N. P.; Riedmayr, Lisa M.; Hammelmann, Verena; Schön, Christian; Butz, Elisabeth S.; Wahl-Schott, Christian; Biel, Martin und Michalakis, Stylianos
(2016):
AAV Vectors for FRET-Based Analysis of Protein-Protein Interactions in Photoreceptor Outer Segments.
In: Frontiers in Neuroscience, Bd. 10, 356
[PDF, 3MB]
2012
Schön, Christian; Hoffmann, Nadine A.; Ochs, Simon M.; Burgold, Steffen; Filser, Severin; Steinbach, Sonja; Seeliger, Mathias W.; Arzberger, Thomas; Goedert, Michel; Kretzschmar, Hans A.; Schmidt, Boris und Herms, Jochen
(2012):
Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice.
In: PLOS ONE 7(12), e53547 [PDF, 7MB]
In: PLOS ONE 7(12), e53547 [PDF, 7MB]