![[höher]](/style/images/multi_up.png)
Eine Ebene höherGruppiert nach: Dokumententyp |
Veröffentlichungsdatum
Anzahl der Publikationen: 111
2024
Leu, Chia-Luen; Lam, Daniel D.; Salminen, Aaro; Wefers, Benedikt; Becker, Lore; Garrett, Lillian; Rozman, Jan; Wurst, Wolfgang; de Angelis, Martin Hrabe; Hoelter, Sabine M.; Winkelmann, Juliane und Williams, Rhiannan H.
(2024):
A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice.
In: Sleep, Bd. 47, Nr. 5
Xu, Meng; Ito-Kureha, Taku; Kang, Hyun-Seo; Chernev, Aleksandar; Raj, Timsse; Hoefig, Kai P.; Hohn, Christine; Giesert, Florian; Wang, Yinhu; Pan, Wenliang; Zietara, Natalia; Straub, Tobias; Feederle, Regina; Daniel, Carolin; Adler, Barbara; Koenig, Julian; Feske, Stefan; Tsokos, George C.; Wurst, Wolfgang; Urlaub, Henning; Sattler, Michael; Kisielow, Jan; Wulczyn, F. Gregory; Lyszkiewicz, Marcin und Heissmeyer, Vigo
(2024):
The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression.
In: Nature Communications, Bd. 15, Nr. 1, 2194
[PDF, 7MB]
Hembach, Sina; Schmidt, Sebastian; Orschmann, Tanja; Burtscher, Ingo; Lickert, Heiko; Giesert, Florian; Weisenhorn, Daniela Vogt und Wurst, Wolfgang
(2024):
Engrailed 1 deficiency induces changes in ciliogenesis during human neuronal differentiation.
In: Neurobiology of Disease, Bd. 194, 106474
[PDF, 12MB]
Giusti, Sebastian A. 
ORCID: https://orcid.org/0000-0002-0257-3027; Pino, Natalia S. ORCID: https://orcid.org/0009-0001-6984-1751; Pannunzio, Camila; Ogando, Mora B. ORCID: https://orcid.org/0000-0002-1453-2628; Armando, Natalia G. ORCID: https://orcid.org/0000-0003-1379-4025; Garrett, Lillian ORCID: https://orcid.org/0000-0003-4880-7076; Zimprich, Annemarie ORCID: https://orcid.org/0000-0003-2078-6779; Becker, Lore ORCID: https://orcid.org/0000-0002-6890-4984; Gimeno, Maria L.; Lukin, Jeronimo ORCID: https://orcid.org/0000-0002-2284-7152; Merino, Florencia L. ORCID: https://orcid.org/0000-0001-7247-2750; Pardi, M. Belen ORCID: https://orcid.org/0000-0003-1942-7533; Pedroncini, Olivia ORCID: https://orcid.org/0009-0009-0613-4126; Di Mauro, Giuliana C. ORCID: https://orcid.org/0000-0001-5685-090X; Durner, Valerie Gailus; Fuchs, Helmut; Hrabe de Angelis, Martin ORCID: https://orcid.org/0000-0002-7898-2353; Patop, Ines L. ORCID: https://orcid.org/0000-0002-2929-0860; Turck, Christoph W. ORCID: https://orcid.org/0000-0002-6585-8636; Deussing, Jan M. ORCID: https://orcid.org/0000-0002-9329-5252; Vogt Weisenhorn, Daniela M. ORCID: https://orcid.org/0000-0002-4566-6506; Jahn, Olaf ORCID: https://orcid.org/0000-0002-3397-8924; Kadener, Sebastian; Hölter, Sabine M. ORCID: https://orcid.org/0000-0003-4878-5241; Brose, Nils ORCID: https://orcid.org/0000-0003-0938-8534; Giesert, Florian ORCID: https://orcid.org/0000-0001-6825-8858; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Marin-Burgin, Antonia ORCID: https://orcid.org/0000-0003-0684-9796 und Refojo, Damian ORCID: https://orcid.org/0000-0002-9798-6413
(2024):
A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuli.
In: Science Advances, Bd. 10, Nr. 21
[PDF, 5MB]
ORCID: https://orcid.org/0000-0002-0257-3027; Pino, Natalia S. ORCID: https://orcid.org/0009-0001-6984-1751; Pannunzio, Camila; Ogando, Mora B. ORCID: https://orcid.org/0000-0002-1453-2628; Armando, Natalia G. ORCID: https://orcid.org/0000-0003-1379-4025; Garrett, Lillian ORCID: https://orcid.org/0000-0003-4880-7076; Zimprich, Annemarie ORCID: https://orcid.org/0000-0003-2078-6779; Becker, Lore ORCID: https://orcid.org/0000-0002-6890-4984; Gimeno, Maria L.; Lukin, Jeronimo ORCID: https://orcid.org/0000-0002-2284-7152; Merino, Florencia L. ORCID: https://orcid.org/0000-0001-7247-2750; Pardi, M. Belen ORCID: https://orcid.org/0000-0003-1942-7533; Pedroncini, Olivia ORCID: https://orcid.org/0009-0009-0613-4126; Di Mauro, Giuliana C. ORCID: https://orcid.org/0000-0001-5685-090X; Durner, Valerie Gailus; Fuchs, Helmut; Hrabe de Angelis, Martin ORCID: https://orcid.org/0000-0002-7898-2353; Patop, Ines L. ORCID: https://orcid.org/0000-0002-2929-0860; Turck, Christoph W. ORCID: https://orcid.org/0000-0002-6585-8636; Deussing, Jan M. ORCID: https://orcid.org/0000-0002-9329-5252; Vogt Weisenhorn, Daniela M. ORCID: https://orcid.org/0000-0002-4566-6506; Jahn, Olaf ORCID: https://orcid.org/0000-0002-3397-8924; Kadener, Sebastian; Hölter, Sabine M. ORCID: https://orcid.org/0000-0003-4878-5241; Brose, Nils ORCID: https://orcid.org/0000-0003-0938-8534; Giesert, Florian ORCID: https://orcid.org/0000-0001-6825-8858; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Marin-Burgin, Antonia ORCID: https://orcid.org/0000-0003-0684-9796 und Refojo, Damian ORCID: https://orcid.org/0000-0002-9798-6413
(2024):
A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuli.
In: Science Advances, Bd. 10, Nr. 21
[PDF, 5MB]
2023
Stroo, Esther; Janssen, Leen; Sin, Olga; Hogewerf, Wytse; Koster, Mirjam; Harkema, Liesbeth; Youssef, Sameh A.; Beschorner, Natalie; Wolters, Anouk H. G.; Bakker, Bjorn; Becker, Lore; Garrett, Lilian; Marschall, Susan; Hoelter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Thathiah, Amanth; Foijer, Floris; Sluis, Bart van de; Deursen, Jan van; Jucker, Matthias; Brun, Alain de und Nollen, Ellen A. A.
(2023):
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain.
In: Life Science Alliance, Bd. 6, Nr. 7, e202201730
[PDF, 2MB]
Schmidt, Henrik; Raj, Timsse; O'Neill, Thomas J.; Muschaweckh, Andreas; Giesert, Florian; Negraschus, Arlinda; Hoefig, Kai P.; Behrens, Gesine; Esser, Lena; Baumann, Christina; Feederle, Regina; Plaza-Sirvent, Carlos; Geerlof, Arie; Gewies, Andreas; Isay, Sophie E.; Ruland, Juergen; Schmitz, Ingo; Wurst, Wolfgang; Korn, Thomas; Krappmann, Daniel und Heissmeyer, Vigo
(2023):
Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 120, Nr. 48, e2309205120
[PDF, 2MB]
Schmidt, Sebastian; Stautner, Constantin; Vu, Duc Tung; Heinz, Alexander; Regensburger, Martin; Karayel, Ozge; Truembach, Dietrich; Artati, Anna; Kaltenhaeuser, Sabine; Nassef, Mohamed Zakaria; Hembach, Sina; Steinert, Letyfee; Winner, Beate; Juergen, Winkler; Jastroch, Martin; Luecken, Malte D.; Theis, Fabian J.; Westmeyer, Gil Gregor; Adamski, Jerzy; Mann, Matthias; Hiller, Karsten; Giesert, Florian; Weisenhorn, Daniela M. Vogt und Wurst, Wolfgang
(2023):
A reversible state of hypometabolism in a human cellular model of sporadic Parkinson's disease.
In: Nature Communications, Bd. 14, Nr. 1, 7674
[PDF, 7MB]
Gonzalez-Garcia, Ismael; Garcia-Clave, Elena; Cebrian-Serrano, Alberto; Le Thuc, Ophlia; Contreras, Raian E.; Xu, Yanjun; Gruber, Tim; Schriever, Sonja C.; Legutko, Beata; Lintelmann, Jutta; Adamski, Jerzy; Wurst, Wolfgang; Mueller, Timo D.; Woods, Stephen C.; Pfluger, Paul T.; Tschoep, Matthias H.; Fisette, Alexandre und Garcia-Caceres, Cristina
(2023):
Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1.
In: Cell Metabolism, Bd. 35, Nr. 3:
438-+
[PDF, 6MB]
Wefers, Benedikt; Wurst, Wolfgang und Kühn, Ralf
(2023):
Gene Editing in Mouse Zygotes Using the CRISPR/Cas9 System.
In: Saunders, Thomas L. (Hrsg.):
Transgenesis. Methods and Protocols. Methods in Molecular Biology, Bd. 2631. New York: Humana Press. S. 207-230
2022
Dening, Yanina; Straßl, Theresa; Ruf, Viktoria; Dirscherl, Petra; Chovsepian, Alexandra; Stievenard, Alicia; Khairnar, Amit; Schmidt, Felix; Giesert, Florian; Herms, Jochen; Levin, Johannes; Dieterich, Marianne; Falkai, Peter; Weisenhorn, Daniela Vogt; Wurst, Wolfgang; Giese, Armin und Pan-Montojo, Francisco
(19. Dezember 2022):
Toxicity of extracellular alpha-synuclein is independent of intracellular alpha-synuclein.
In: Scientific Reports, Bd. 12, Nr. 1
[PDF, 9MB]
Stafford, Che A.; Gassauer, Alicia-Marie; Oliveira Mann, Carina C. de; Tanzer, Maria C. ORCID: https://orcid.org/0000-0002-4657-9869; Fessler, Evelyn; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Nagl, Dennis; Kuut, Gunnar; Sulek, Karolina; Vasilopoulou, Catherine; Schwojer, Sophia J. ORCID: https://orcid.org/0000-0002-1747-4144; Wiest, Andreas ORCID: https://orcid.org/0000-0003-2525-6304; Pfautsch, Marie K.; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Yabal, Monica ORCID: https://orcid.org/0000-0003-3495-7671; Fröhlich, Thomas ORCID: https://orcid.org/0000-0002-4709-3211; Mann, Matthias ORCID: https://orcid.org/0000-0003-1292-4799; Gisch, Nicolas ORCID: https://orcid.org/0000-0003-3260-5269; Jae, Lucas T. ORCID: https://orcid.org/0000-0002-3531-1760 und Hornung, Veit ORCID: https://orcid.org/0000-0002-4150-194X
(2022):
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation.
In: Nature, Bd. 609: S. 590-596
[PDF, 10MB]
ORCID: https://orcid.org/0000-0002-4657-9869; Fessler, Evelyn; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Nagl, Dennis; Kuut, Gunnar; Sulek, Karolina; Vasilopoulou, Catherine; Schwojer, Sophia J. ORCID: https://orcid.org/0000-0002-1747-4144; Wiest, Andreas ORCID: https://orcid.org/0000-0003-2525-6304; Pfautsch, Marie K.; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Yabal, Monica ORCID: https://orcid.org/0000-0003-3495-7671; Fröhlich, Thomas ORCID: https://orcid.org/0000-0002-4709-3211; Mann, Matthias ORCID: https://orcid.org/0000-0003-1292-4799; Gisch, Nicolas ORCID: https://orcid.org/0000-0003-3260-5269; Jae, Lucas T. ORCID: https://orcid.org/0000-0002-3531-1760 und Hornung, Veit ORCID: https://orcid.org/0000-0002-4150-194X
(2022):
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation.
In: Nature, Bd. 609: S. 590-596
[PDF, 10MB]
Stirm, Michael; Fonteyne, Lina Marie; Shashikadze, Bachuki; Stoeckl, Jan B.; Kurome, Mayuko; Kessler, Barbara; Zakhartchenko, Valeri; Kemter, Elisabeth; Blum, Helmut; Arnold, Georg J.; Matiasek, Kaspar; Wanke, Ruediger; Wurst, Wolfgang; Nagashima, Hiroshi; Knieling, Ferdinand; Walter, Maggie C.; Kupatt, Christian; Froehlich, Thomas; Klymiuk, Nikolai; Blutke, Andreas und Wolf, Eckhard
(2022):
Pig models for Duchenne muscular dystrophy-from disease mechanisms to validation of new diagnostic and therapeutic concepts.
In: Neuromuscular Disorders, Bd. 32, Nr. 7: S. 543-556
Garrett, Lillian; Truembach, Dietrich; Spielmann, Nadine; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; De Angelis, Martin Hrabe und Hoelter, Sabine M.
(2022):
A rationale for considering heart/brain axis control in neuropsychiatric disease.
In: Mammalian Genome, Bd. 34, Nr. 2: S. 331-350
[PDF, 7MB]
Vetrivel, Sharmilee; Truong, Dong-Jiunn Jeffery; Wurst, Wolfgang; Graw, Jochen und Giesert, Florian
(2022):
Identification of ocular regulatory functions of core histone variant H3.2.
In: Experimental Eye Research, Bd. 226, 109346
Schmidt, Sebastian; Luecken, Malte D.; Truembach, Dietrich; Hembach, Sina; Niedermeier, Kristina M.; Wenck, Nicole; Pfluegler, Klaus; Stautner, Constantin; Boettcher, Anika; Lickert, Heiko; Ramirez-Suastegui, Ciro; Ahmad, Ruhel; Ziller, Michael J.; Fitzgerald, Julia C.; Ruf, Viktoria; Berg, Wilma D. J. van de; Jonker, Allert J.; Gasser, Thomas; Winner, Beate; Winkler, Juergen; Weisenhorn, Daniela M. Vogt; Giesert, Florian; Theis, Fabian J. und Wurst, Wolfgang
(2022):
Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.
In: Nature Communications, Bd. 13, Nr. 1, 4819
[PDF, 5MB]
Garrett, Lillian; Da Silva-Buttkus, Patricia; Rathkolb, Birgit; Gerlini, Raffaele; Becker, Lore; Sanz-Moreno, Adrian; Seisenberger, Claudia; Zimprich, Annemarie; Aguilar-Pimentel, Antonio; Amarie, Oana V.; Cho, Yi-Li; Kraiger, Markus; Spielmann, Nadine; Calzada-Wack, Julia; Marschall, Susan; Busch, Dirk; Schmitt-Weber, Carsten; Wolf, Eckhard; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hoelter, Sabine M. und de Angelis, Martin Hrabe
(2022):
Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk.
In: Disease Models & Mechanisms, Bd. 15, Nr. 3, dmm049205
[PDF, 2MB]
Giehrl-Schwab, Jessica; Giesert, Florian; Rauser, Benedict; Lao, Chu Lan; Hembach, Sina; Lefort, Sandrine; Ibarra, Ignacio L.; Koupourtidou, Christina; Luecken, Malte Daniel; Truong, Dong-Jiunn Jeffery; Fischer-Sternjak, Judith; Masserdotti, Giacomo; Prakash, Nilima; Ninkovic, Jovica; Hoelter, Sabine M.; Weisenhorn, Daniela M. Vogt; Theis, Fabian J.; Goetz, Magdalena und Wurst, Wolfgang
(2022):
Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons.
In: EMBO Molecular Medicine, Bd. 14, Nr. 5, e14797
[PDF, 3MB]
Falkai, Peter; Koutsouleris, Nikolaos; Bertsch, Katja; Bialas, Mirko; Binder, Elisabeth; Buehner, Markus; Buyx, Alena; Cai, Na; Cappello, Silvia; Ehring, Thomas; Gensichen, Jochen; Hamann, Johannes; Hasan, Alkomiet; Henningsen, Peter; Leucht, Stefan; Moehrmann, Karl Heinz; Nagelstutz, Elisabeth; Padberg, Frank; Peters, Annette; Pfaeffel, Lea; Reich-Erkelenz, Daniela; Riedl, Valentin; Rueckert, Daniel; Schmitt, Andrea; Schulte-Koerne, Gerd; Scheuring, Elfriede; Schulze, Thomas G.; Starzengruber, Rudolf; Stier, Susanne; Theis, Fabian J.; Winkelmann, Juliane; Wurst, Wolfgang und Priller, Josef
(2022):
Concept of the Munich/Augsburg Consortium Precision in Mental Health for the German Center of Mental Health.
In: Frontiers in Psychiatry, Bd. 13, 815718
Sanchez-Gonzalez, Rosario; Koupourtidou, Christina; Lepko, Tjasa; Zambusi, Alessandro; Novoselc, Klara Tereza; Durovic, Tamara; Aschenbroich, Sven; Schwarz, Veronika; Breunig, Christopher T.; Straka, Hans; Huttner, Hagen B.; Irmler, Martin; Beckers, Johannes; Wurst, Wolfgang; Zwergal, Andreas; Schauer, Tamas; Straub, Tobias; Czopka, Tim; Trümbach, Dietrich; Götz, Magdalena; Stricker, Stefan H. und Ninkovic, Jovica
(2022):
Innate Immune Pathways Promote Oligodendrocyte Progenitor Cell Recruitment to the Injury Site in Adult Zebrafish Brain.
In: Cells, Bd. 11, Nr. 3, 520
[PDF, 9MB]
Xie, Kan; Fuchs, Helmut; Scifo, Enzo; Liu, Dan; Aziz, Ahmad; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; da Silva-Buttkus, Patricia; Calzada-Wack, Julia; Cho, Yi-Li; Deng, Yushuang; Edwards, A. Cole; Garrett, Lillian; Georgopoulou, Christina; Gerlini, Raffaele; Hoelter, Sabine M.; Klein-Rodewald, Tanja; Kramer, Michael; Leuchtenberger, Stefanie; Lountzi, Dimitra; Mayer-Kuckuk, Phillip; Nover, Lena L.; Oestereicher, Manuela A.; Overkott, Clemens; Pearson, Brandon L.; Rathkolb, Birgit; Rozman, Jan; Russ, Jenny; Schaaf, Kristina; Spielmann, Nadine; Sanz-Moreno, Adrian; Stoeger, Claudia; Treise, Irina; Bano, Daniele; Busch, Dirk H.; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Mock, Beverly A.; Salomoni, Paolo; Schmidt-Weber, Carsten; Weiergraber, Marco; Wolf, Eckhard; Wurst, Wolfgang; Gailus-Durner, Valerie; Breteler, Monique M. B.; Hrabe de Angelis, Martin und Ehninger, Dan
(2022):
Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.
In: Nature Communications, Bd. 13, Nr. 1, 6830
[PDF, 7MB]
Maity-Kumar, Gandhari; Staender, Lisa; DeAngelis, Meri; Lee, Sooyeon; Molenaar, Anna; Becker, Lore; Garrett, Lillian; Amerie, Oana; Hoelter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Feuchtinger, Annette; Gailus-Durner, Valerie; Gárcia-Cáceres, Cristina; Othman, Ahmed E.; Brockmann, Caroline; Schoeffling, Vanessa I.; Beiser, Katja; Krude, Heiko; Mroz, Piotr A.; Hofmann, Susanna; Tuckermann, Jan; DiMarchi, Richard D.; de Angelis, Martin Hrabe; Tschoep, Matthias H.; Pfluger, Paul T. und Mueller, Timo D.
(2022):
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.
In: Molecular Metabolism, Bd. 66, 101616
[PDF, 3MB]
Danileviciute, Egle; Zeng, Ni; Capelle, Christophe M.; Paczia, Nicole; Gillespie, Mark A.; Kurniawan, Henry; Benzarti, Mohaned; Merz, Myriam P.; Coowar, Djalil; Fritah, Sabrina; Weisenhorn, Daniela Maria Vogt; Giro, Gemma Gomez; Grusdat, Melanie; Baron, Alexandre; Guerin, Coralie; Franchina, Davide G.; Leonard, Cathy; Domingues, Olivia; Delhalle, Sylvie; Wurst, Wolfgang; Turner, Jonathan D.; Schwamborn, Jens Christian; Meiser, Johannes; Krueger, Rejko; Ranish, Jeff; Brenner, Dirk; Linster, Carole L.; Balling, Rudi; Ollert, Markus und Hefeng, Feng Q.
(2022):
PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis during ageing.
In: Nature Metabolism, Bd. 4, Nr. 5:
589-+
Schmidt, Sebastian; Weisenhorn, Daniela M. Vogt und Wurst, Wolfgang
(2022):
Chapter 5-Parkinson's disease - A role of non-enzymatic posttranslational modifications in disease onset and progression?
In: Molecular Aspects of Medicine, Bd. 86, 101096
[PDF, 2MB]
2021
Behrens, Gesine; Edelmann, Stephanie L.; Raj, Timsse; Kronbeck, Nina; Monecke, Thomas; Davydova, Elena; Wong, Elaine H.; Kifinger, Lisa; Giesert, Florian; Kirmaier, Martin E.; Hohn, Christine; de Jonge, Laura S.; Pisfil, Mariano Gonzalez; Fu, Mingui; Theurich, Sebastian; Feske, Stefan; Kawakami, Naoto; Wurst, Wolfgang; Niessing, Dierk und Heissmeyer, Vigo
(2021):
Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses.
In: Nature Immunology, Bd. 22, Nr. 12: S. 1563-1576
Biagosch, Caroline A.; Vidali, Silvia; Faerberboeck, Michael; Hensler, Svenja-Viola; Becker, Lore; Amarie, Oana V.; Aguilar-Pimentel, Antonio; Garrett, Lillian; Klein-Rodewald, Tanja; Rathkolb, Birgit; Zanuttigh, Enrica; Calzada-Wack, Julia; Silva-Buttkus, Patricia da; Rozman, Jan; Treise, Irina; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Janik, Dirk; Wurst, Wolfgang; Mayr, Johannes A.; Klopstock, Thomas; Meitinger, Thomas; Prokisch, Holger und Iuso, Arcangela
(2021):
A comprehensive phenotypic characterization of a whole-body Wdr45 knock-out mouse.
In: Mammalian Genome, Bd. 32, Nr. 5: S. 332-349
[PDF, 3MB]
Frey, Laura; Zietara, Natalia; Lyszkiewicz, Marcin; Marquardt, Benjamin; Mizoguchi, Yoko; Linder, Monika I.; Liu, Yanshan; Giesert, Florian; Wurst, Wolfgang; Dahlhoff, Maik; Schneider, Marlon R.; Wolf, Eckhard; Somech, Raz und Klein, Christoph
(2021):
Mammalian VPS45 orchestrates trafficking through the endosomal system.
In: Blood, Bd. 137, Nr. 14: S. 1932-1944
Hansen, Jens; Melchner, Harald von und Wurst, Wolfgang
(2021):
Mutant non-coding RNA resource in mouse embryonic stem cells.
In: Disease Models & Mechanisms, Bd. 14, Nr. 2, dmm047803
[PDF, 719kB]
Kupatt, Christian; Windisch, Alina; Moretti, Alessandra; Wolf, Eckhard; Wurst, Wolfgang und Walter, Maggie C.
(2021):
Genome editing for Duchenne muscular dystrophy: a glimpse of the future?
In: Gene Therapy, Bd. 28, Nr. 9: S. 542-548
[PDF, 904kB]
O'Neill, Thomas J.; Seeholzer, Thomas; Gewies, Andreas; Gehring, Torben; Giesert, Florian; Hamp, Isabel; Grass, Carina; Schmidt, Henrik; Kriegsmann, Katharina; Tofaute, Marie J.; Demski, Katrin; Poth, Tanja; Rosenbaum, Marc; Schnalzger, Theresa; Ruland, Jürgen; Goettlicher, Martin; Kriegsmann, Mark; Naumann, Ronald; Heissmeyer, Vigo; Plettenburg, Oliver; Wurst, Wolfgang und Krappmann, Daniel
(2021):
TRAF6 prevents fatal inflammation by homeostatic suppression of MALT1 protease.
In: Science Immunology, Bd. 6, Nr. 65, eabh2095
Russo, Gianluca L.; Sonsalla, Giovanna; Natarajan, Poornemaa; Breunig, Christopher T.; Bulli, Giorgia; Merl-Pham, Juliane; Schmitt, Sabine; Giehrl-Schwab, Jessica; Giesert, Florian; Jastroch, Martin; Zischka, Hans; Wurst, Wolfgang; Stricker, Stefan H.; Hauck, Stefanie M.; Masserdotti, Giacomo und Goetz, Magdalena
(2021):
CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion.
In: Cell Stem Cell, Bd. 28, Nr. 3: S. 524-534
[PDF, 4MB]
Schaenzer, Anne; Achleitner, Melanie T.; Truembach, Dietrich; Hubert, Laurence; Munnich, Arnold; Ahlemeyer, Barbara; AlAbdulrahim, Maha M.; Greif, Philipp A.; Vosberg, Sebastian; Hummer, Blake; Feichtinger, Rene G.; Mayr, Johannes A.; Wortmann, Saskia B.; Aichner, Heidi; Rudnik-Schoeneborn, Sabine; Ruiz, Anna; Gabau, Elisabeth; Sanchez, Jacobo Perez; Ellard, Sian; Homfray, Tessa; Stals, Karen L.; Wurst, Wolfgang; Neubauer, Bernd A.; Acker, Till; Bohlander, Stefan K.; Asensio, Cedric; Besmond, Claude; Alkuraya, Fowzan S.; AlSayed, Moenaldeen D.; Hahn, Andreas und Weber, Axel
(2021):
Mutations in HID1 Cause Syndromic Infantile Encephalopathy and Hypopituitarism.
In: Annals of Neurology, Bd. 90, Nr. 1: S. 143-158
[PDF, 7MB]
Vidali, Silvia; Gerlini, Raffaele; Thompson, Kyle; Urquhart, Jill E.; Meisterknecht, Jana; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Breen, Catherine; Calzada-Wack, Julia; Chhabra, Nirav F.; Cho, Yi-Li; Silva-Buttkus, Patricia da; Feichtinger, Rene G.; Gampe, Kristine; Garrett, Lillian; Hoefig, Kai P.; Hoelter, Sabine M.; Jameson, Elisabeth; Klein-Rodewald, Tanja; Leuchtenberger, Stefanie; Marschall, Susan; Mayer-Kuckuk, Philipp; Miller, Gregor; Oestereicher, Manuela A.; Pfannes, Kristina; Rathkolb, Birgit; Rozman, Jan; Sanders, Charlotte; Spielmann, Nadine; Stoeger, Claudia; Szibor, Marten; Treise, Irina; Walter, John H.; Wurst, Wolfgang; Mayr, Johannes A.; Fuchs, Helmut; Gaertner, Ulrich; Wittig, Ilka; Taylor, Robert W.; Newman, William G.; Prokisch, Holger; Gailus-Durner, Valerie und Hrabe de Angelis, Martin
(2021):
Characterising a homozygous two-exon deletion in UQCRH: comparing human and mouse phenotypes.
In: EMBO Molecular Medicine, Bd. 13, Nr. 12, e14397
Weisheit, Isabel; Kroeger, Joseph A.; Malik, Rainer; Wefers, Benedikt; Lichtner, Peter; Wurst, Wolfgang; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X und Paquet, Dominik
(2021):
Simple and reliable detection of CRISPR-induced on-target effects by qgPCR and SNP genotyping.
In: Nature Protocols, Bd. 16, Nr. 3: S. 1714-1739
ORCID: https://orcid.org/0000-0002-0654-387X und Paquet, Dominik
(2021):
Simple and reliable detection of CRISPR-induced on-target effects by qgPCR and SNP genotyping.
In: Nature Protocols, Bd. 16, Nr. 3: S. 1714-1739
Findeiss, Elisabeth; Schwarz, Sigrid C.; Evsyukov, Valentin; Roesler, Thomas W.; Hoellerhage, Matthias; Chakroun, Tasnim; Nykaenen, Niko-Petteri; Shen, Yimin; Wurst, Wolfgang; Kohl, Michael; Tost, Joerg und Hoeglinger, Guenter U.
(2021):
Comprehensive miRNome-Wide Profiling in a Neuronal Cell Model of Synucleinopathy Implies Involvement of Cell Cycle Genes.
In: Frontiers in Cell and Developmental Biology, Bd. 9, 561086
[PDF, 5MB]
Hsia, Hung-En; Tueshaus, Johanna; Feng, Xiao; Hofmann, Laura; Wefers, Benedikt; Marciano, Denise K.; Wurst, Wolfgang und Lichtenthaler, Stefan F.
(2021):
Endoglycan (PODXL2) is proteolytically processed by ADAM10 (a disintegrin and metalloprotease 10) and controls neurite branching in primary neurons.
In: Faseb Journal, Bd. 35, Nr. 9, e21813
[PDF, 1MB]
Ung, Marie-Claire; Garrett, Lillian; Dalke, Claudia; Leitner, Valentin; Dragosa, Daniel; Hladik, Daniela; Neff, Frauke; Wagner, Florian; Zitzelsberger, Horst; Miller, Gregor; de Angelis, Martin Hrabe; Roessler, Ute; Vogt Weisenhorn, Daniela; Wurst, Wolfgang; Graw, Jochen und Hoelter, Sabine M.
(2021):
Dose-dependent long-term effects of a single radiation event on behaviour and glial cells.
In: International Journal of Radiation Biology, Bd. 97, Nr. 2: S. 156-169
[PDF, 3MB]
Brandes, Ralf P.; Dueck, Anne; Engelhardt, Stefan; Kaulich, Manuel; Kupatt, Christian; De Angelis, Maria Teresa; Leisegang, Matthias S.; le Noble, Ferdinand; Moretti, Alessandra; Mueller, Oliver J.; Skryabin, Boris V.; Thum, Thomas und Wurst, Wolfgang
(2021):
DGK and DZHK position paper on genome editing: basic science applications and future perspective.
In: Basic Research in Cardiology, Bd. 116, Nr. 1, 2
[PDF, 2MB]
Baumann, Peter; Schriever, Sonja C.; Kullmann, Stephanie; Zimprich, Annemarie; Peter, Andreas; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Wurst, Wolfgang; Tschoep, Matthias H.; Heni, Martin; Hoelter, Sabine M. und Pfluger, Paul T.
(2021):
Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans.
In: Brain and Behavior, Bd. 11, Nr. 1, e01928
[PDF, 705kB]
2020
Kollmus, Heike; Fuchs, Helmut; Lengger, Christoph; Haselimashhadi, Hamed; Bogue, Molly A.; Ostereicher, Manuela A.; Horsch, Marion; Adler, Thure; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; Beckers, Johannes; Calzada-Wack, Julia; Garrett, Lillian; Hans, Wolfgang; Hoelter, Sabine M.; Klein-Rodewald, Tanja; Maier, Holger; Mayer-Kuckuk, Philipp; Miller, Gregor; Moreth, Kristin; Neff, Frauke; Rathkolb, Birgit; Racz, Ildiko; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Busch, Dirk; Graw, Jochen; Klopstock, Thomas; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Onder; Mason, Jeremy; Torres, Arturo; Balling, Rudi; Mehaan, Terry; Gailus-Durner, Valerie; Schughart, Klaus und de Angelis, Martin Hrabe
(2020):
A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.
In: Mammalian Genome, Bd. 31: S. 30-48
[PDF, 3MB]
LaClair, Katherine D.; Zhou, Qihui; Michaelsen, Meike; Wefers, Benedikt; Brill, Monika S.; Janjic, Aleksandar; Rathkolb, Birgit; Farny, Daniel; Cygan, Mikolaj; de Angelis, Martin Hrabe; Wurst, Wolfgang; Neumann, Manuela; Enard, Wolfgang; Misgeld, Thomas; Arzberger, Thomas und Edbauer, Dieter
(2020):
Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
In: Acta Neuropathologica, Bd. 140, Nr. 2: S. 121-142
[PDF, 8MB]
Lüningschöor, Patrick; Wemer, Georg; Stroobants, Stijn; Kakuta, Soichiro; Dombert, Benjamin; Sinske, Daniela; Wanner, Renate; Luellmann-Rauch, Renate; Wefers, Benedikt; Wurst, Wolfgang; D'Hooge, Rudi; Uchiyama, Yasuo; Sendtner, Michael; Haass, Christian; Saftig, Paul; Knöll, Bernd; Capell, Anja und Damme, Markus
(2020):
The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons.
In: Cell Reports, Bd. 30, Nr. 10: S. 3506-3519
[PDF, 7MB]
Chakroun, Tasnim; Evsyukov, Valentin; Nykaenen, Niko-Petteri; Hoellerhage, Matthias; Schmidt, Andreas; Kamp, Frits; Ruf, Viktoria C.; Wurst, Wolfgang; Roesler, Thomas W. und Höglinger, Günter U.
(2020):
Alpha-synuclein fragments trigger distinct aggregation pathways.
In: Cell Death & Disease, Bd. 11, Nr. 2
[PDF, 3MB]
Takalo, Mari; Wittrahm, Rebekka; Wefers, Benedikt; Parhizkar, Samira; Jokivarsi, Kimmo; Kuulasmaa, Teemu; Makinen, Petra; Martiskainen, Henna; Wurst, Wolfgang; Xiang, Xianyuan; Marttinen, Mikael; Poutiainen, Pekka; Haapasalo, Annakaisa; Hiltunen, Mikko und Haass, Christian
(2020):
The Alzheimer's disease-associated protective Plc gamma 2-P522R variant promotes immune functions.
In: Molecular Neurodegeneration, Bd. 15, Nr. 1, 52
[PDF, 4MB]
Swan, Anna L.; Schuett, Christine; Rozman, Jan; Moreno, Maria del Mar Muniz; Brandmaier, Stefan; Simon, Michelle; Leuchtenberger, Stefanie; Griffiths, Mark; Brommage, Robert; Keskivali-Bond, Piia; Grallert, Harald; Werner, Thomas; Teperino, Raffaele; Becker, Lore; Miller, Gregor; Moshiri, Ala; Seavitt, John R.; Cissell, Derek D.; Meehan, Terrence F.; Acar, Elif F.; Lelliott, Christopher J.; Flenniken, Ann M.; Champy, Marie-France; Sorg, Tania; Ayadi, Abdel; Braun, Robert E.; Cater, Heather; Dickinson, Mary E.; Flicek, Paul; Gallegos, Juan; Ghirardello, Elena J.; Heaney, Jason D.; Jacquot, Sylvie; Lally, Connor; Logan, John G.; Teboul, Lydia; Mason, Jeremy; Spielmann, Nadine; McKerlie, Colin; Murray, Stephen A.; Nutter, Lauryl M. J.; Odfalk, Kristian F.; Parkinson, Helen; Prochazka, Jan; Reynolds, Corey L.; Selloum, Mohammed; Spoutil, Frantisek; Svenson, Karen L.; Vales, Taylor S.; Wells, Sara E.; White, Jacqueline K.; Sedlacek, Radislav; Wurst, Wolfgang; Lloyd, Kent K. C.; Croucher, Peter; Fuchs, Helmut; Williams, Graham R.; Bassett, Duncan; Gailus-Durner, Valerie; Herault, Yann; Mallon, Ann-Marie; Brown, Steve D. M.; Mayer-Kuckuk, Philipp und de Angelis, Martin Hrabe
(2020):
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.
In: PLOS Genetics 16(12), e1009190 [PDF, 2MB]
In: PLOS Genetics 16(12), e1009190 [PDF, 2MB]
Werner, Georg; Damme, Markus; Schludi, Martin; Gnoerich, Johannes; Wind, Karin; Fellerer, Katrin; Wefers, Benedikt; Wurst, Wolfgang; Edbauer, Dieter; Brendel, Matthias; Haass, Christian und Capell, Anja
(2020):
Loss ofTMEM106B potentiates lysosomal andFTLD-like pathology in progranulin-deficient mice.
In: EMBO Reports, Bd. 21, Nr. 10, e50241
[PDF, 4MB]
Lucienne, Marie; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Silva-Buttkus, Patricia da; Garrett, Lillian; Holter, Sabine M.; Mayer-Kuckuk, Philipp; Rathkolb, Birgit; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Busch, Dirk H.; Klopstock, Thomas; Schmidt-Weber, Carsten; Wolf, Eckhard; Wurst, Wolfgang; Forny, Merima; Mathis, Deborah; Fingerhut, Ralph; Froese, D. Sean; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin und Baumgartner, Matthias R.
(2020):
In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria.
In: Biochimica et Biophysica Acta-Molecular Basis of Disease, Bd. 1866, Nr. 3, 165622
[PDF, 2MB]
Ignatova, Valentina V.; Stolz, Paul; Kaiser, Steffen; Gustafsson, Tobias H.; Lastres, Palma Rico; Sanz-Moreno, Adrian; Cho, Yi-Li; Amarie, Oana V.; Aguilar-Pimentel, Antonio; Klein-Rodewald, Tanja; Calzada-Wack, Julia; Becker, Lore; Marschall, Susan; Kraiger, Markus; Garrett, Lillian; Seisenberger, Claudia; Hoelter, Sabine M.; Borland, Kayla; Logt, Erik van de; Jansen, Pascal W. T. C.; Baltissen, Marijke P.; Valenta, Magdalena; Vermeulen, Michiel; Wurst, Wolfgang; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Rando, Oliver J.; Kellner, Stefanie M.; Bultmann, Sebastian und Schneider, Robert
(2020):
The rRNA m(6)A methyltransferase METTL5 is involved in pluripotency and developmental programs.
In: Genes & Development, Bd. 34: S. 715-729
[PDF, 4MB]
Garrett, Lillian; Chang, Yoon Jeung; Niedermeier, Kristina M.; Heermann, Tamara; Enard, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Huttner, Wieland B.; Wurst, Wolfgang und Hoelter, Sabine M.
(2020):
A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons.
In: Translational Psychiatry, Bd. 10, Nr. 1, 66
[PDF, 1MB]
Nouri, Parivash; Goetz, Sebastian; Rauser, Benedict; Irmler, Martin; Peng, Changgeng; Truembach, Dietrich; Kempny, Christian; Lechermeier, Carina G.; Bryniok, Agnes; Dlugos, Andrea; Euchner, Ellen; Beckers, Johannes; Brodski, Claude; Kluemper, Claudia; Wurst, Wolfgang und Prakash, Nilima
(2020):
Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling.
In: Frontiers in Cell and Developmental Biology, Bd. 8, 587778
[PDF, 13MB]
Lloyd, K. C. Kent; Adams, David J.; Baynam, Gareth; Beaudet, Arthur L.; Bosch, Fatima; Boycott, Kym M.; Braun, Robert E.; Caulfield, Mark; Cohn, Ronald; Dickinson, Mary E.; Dobbie, Michael S.; Flenniken, Ann M.; Flicek, Paul; Galande, Sanjeev; Gao, Xiang; Grobler, Anne; Heaney, Jason D.; Herault, Yann; De Angelis, Martin Hrabe; Lupski, James R.; Lyonnet, Stanislas; Mallon, Ann-Marie; Mammano, Fabio; MacRae, Calum A.; McInnes, Roderick; McKerlie, Colin; Meehan, Terrence F.; Murray, Stephen A.; Nutter, Lauryl M. J.; Obata, Yuichi; Parkinson, Helen; Pepper, Michael S.; Sedlacek, Radislav; Seong, Je Kyung; Shiroishi, Toshihiko; Smedley, Damian; Tocchini-Valentini, Glauco; Valle, David; Wang, Chi-Kuang Leo; Wells, Sara; White, Jacqueline; Wurst, Wolfgang; Xu, Ying und Brown, Steve D. M.
(2020):
The Deep Genome Project.
In: Genome Biology, Bd. 21, Nr. 1, 18
[PDF, 609kB]
Vogl, Annette M.; Phu, Lilian; Becerra, Raquel; Giusti, Sebastian A.; Verschueren, Erik; Hinkle, Trent B.; Bordenave, Martin D.; Adrian, Max; Heidersbach, Amy; Yankilevich, Patricio; Stefani, Fernando D.; Wurst, Wolfgang; Hoogenraad, Casper C.; Kirkpatrick, Donald S.; Refojo, Damian und Sheng, Morgan
(2020):
Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics.
In: Nature Structural & Molecular Biology, Bd. 27, Nr. 2
Cacheiro, Pilar; Munoz-Fuentes, Violeta; Murray, Stephen A.; Dickinson, Mary E.; Bucan, Maja; Nutter, Lauryl M. J.; Peterson, Kevin A.; Haselimashhadi, Hamed; Flenniken, Ann M.; Morgan, Hugh; Westerberg, Henrik; Konopka, Tomasz; Hsu, Chih-Wei; Christiansen, Audrey; Lanza, Denise G.; Beaudet, Arthur L.; Heaney, Jason D.; Fuchs, Helmut; Gailus-Durner, Valerie; Sorg, Tania; Prochazka, Jan; Novosadova, Vendula; Lelliott, Christopher J.; Wardle-Jones, Hannah; Wells, Sara; Teboul, Lydia; Cater, Heather; Stewart, Michelle; Hough, Tertius; Wurst, Wolfgang; Sedlacek, Radislav; Adams, David J.; Seavitt, John R.; Tocchini-Valentini, Glauco; Mammano, Fabio; Braun, Robert E.; McKerlie, Colin; Herault, Yann; de Angelis, Martin Hrabe; Mallon, Ann-Marie; Lloyd, K. C. Kent; Brown, Steve D. M.; Parkinson, Helen; Meehan, Terrence F.; Smedley, Damian; Ambrose, J. C.; Arumugam, P.; Baple, E. L.; Bleda, M.; Boardman-Pretty, F.; Boissiere, J. M.; Boustred, C. R.; Brittain, H.; Caulfield, M. J.; Chan, G. C.; Craig, C. E. H.; Daugherty, L. C.; de Burca, A.; Devereau, A.; Elgar, G.; Foulger, R. E.; Fowler, T.; Furio-Tari, P.; Hackett, J. M.; Halai, D.; Hamblin, A.; Henderson, S.; Holman, J. E.; Hubbard, T. J. P.; Ibanez, K.; Jackson, R.; Jones, L. J.; Kasperaviciute, D.; Kayikci, M.; Lahnstein, L.; Lawson, K.; Leigh, S. E. A.; Leong, I. U. S.; Lopez, F. J.; Maleady-Crowe, F.; Mason, J.; McDonagh, E. M.; Moutsianas, L.; Mueller, M.; Murugaesu, N.; Need, A. C.; Odhams, C. A.; Patch, C.; Perez-Gil, D.; Polychronopoulos, D.; Pullinger, J.; Rahim, T.; Rendon, A.; Riesgo-Ferreiro, P.; Rogers, T.; Ryten, M.; Savage, K.; Sawant, K.; Scott, R. H.; Siddiq, A.; Sieghart, A.; Smith, K. R.; Sosinsky, A.; Spooner, W.; Stevens, H. E.; Stuckey, A.; Sultana, R.; Thomas, E. R. A.; Thompson, S. R.; Tregidgo, C.; Tucci, A.; Walsh, E.; Watters, S. A.; Welland, M. J.; Williams, E.; Witkowska, K.; Wood, S. M.; Zarowiecki, M.; Marschall, Susan; Lengger, Christoph; Maier, Holger; Seisenberger, Claudia; Buerger, Antje; Kuehn, Ralf; Schick, Joel; Hoerlein, Andreas; Oritz, Oskar; Giesert, Florian; Beig, Joachim; Kenyon, Janet; Codner, Gemma; Fray, Martin; Johnson, Sara J.; Cleak, James; Szoke-Kovacs, Zsombor; Lafont, David; Vancollie, Valerie E.; McLaren, Robbie S. B.; Hughes-Hallett, Lena; Rowley, Christine; Sanderson, Emma; Galli, Antonella; Tuck, Elizabeth; Green, Angela; Tudor, Catherine; Siragher, Emma; Dabrowska, Monika; Mazzeo, Cecilia Icoresi; Griffiths, Mark; Gannon, David; Doe, Brendan; Cockle, Nicola; Kirton, Andrea; Bottomley, Joanna; Ingle, Catherine; Ryder, Edward; Gleeson, Diane; Ramirez-Solis, Ramiro; Birling, Marie-Christine; Pavlovic, Guillaume; Ayadi, Abdel; Hamid, Meziane; About, Ghina Bou; Champy, Marie-France; Jacobs, Hugues; Wendling, Olivia; Leblanc, Sophie; Vasseur, Laurent; Chesler, Elissa J.; Kumar, Vivek; White, Jacqueline K.; Svenson, Karen L.; Wiegand, Jean-Paul; Anderson, Laura L.; Wilcox, Troy; Clark, James; Ryan, Jennifer; Denegre, James; Stearns, Tim; Philip, Vivek; Witmeyer, Catherine; Bates, Lindsay; Seavey, Zachary; Stanley, Pamela; Willet, Amelia; Roper, Willson; Creed, Julie; Moore, Michayla; Dorr, Alex; Fraungruber, Pamelia; Presby, Rose; Mckay, Matthew; Nguyen-Bresinsky, Dong; Goodwin, Leslie; Urban, Rachel und Kane, Coleen
(2020):
Human and mouse essentiality screens as a resource for disease gene discovery.
In: Nature Communications, Bd. 11, Nr. 1, 655
[PDF, 1MB]
Boussaad, Ibrahim ORCID: https://orcid.org/0000-0002-3512-3364; Obermaier, Carolin D. ORCID: https://orcid.org/0000-0001-6653-8215; Hanss, Zoé ORCID: https://orcid.org/0000-0002-3659-3624; Bobbili, Dheeraj R.; Bolognin, Silvia ORCID: https://orcid.org/0000-0002-1399-2999; Glaab, Enrico ORCID: https://orcid.org/0000-0003-3977-7469; Wołyńska, Katarzyna ORCID: https://orcid.org/0000-0002-8377-8496; Weisschuh, Nicole; De Conti, Laura ORCID: https://orcid.org/0000-0003-4391-3638; May, Caroline ORCID: https://orcid.org/0000-0002-6532-5979; Giesert, Florian ORCID: https://orcid.org/0000-0001-6825-8858; Grossmann, Dajana; Lambert, Annika ORCID: https://orcid.org/0000-0003-4503-4266; Kirchen, Susanne ORCID: https://orcid.org/0000-0003-0211-1815; Biryukov, Maria; Burbulla, Lena F. ORCID: https://orcid.org/0000-0002-6548-905X; Massart, Francois ORCID: https://orcid.org/0000-0001-5590-3344; Bohler, Jill; Cruciani, Gérald; Schmid, Benjamin ORCID: https://orcid.org/0000-0002-0028-888X; Kurz-Drexler, Annerose ORCID: https://orcid.org/0000-0001-9108-6994; May, Patrick ORCID: https://orcid.org/0000-0001-8698-3770; Duga, Stefano ORCID: https://orcid.org/0000-0003-3457-1410; Klein, Christine; Schwamborn, Jens C. ORCID: https://orcid.org/0000-0003-4496-0559; Marcus, Katrin ORCID: https://orcid.org/0000-0002-3313-8845; Woitalla, Dirk; Vogt Weisenhorn, Daniela M. ORCID: https://orcid.org/0000-0002-4566-6506; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Baralle, Marco ORCID: https://orcid.org/0000-0002-0417-1013; Krainc, Dimitri ORCID: https://orcid.org/0000-0002-4716-1886; Gasser, Thomas ORCID: https://orcid.org/0000-0002-1069-1146; Wissinger, Bernd ORCID: https://orcid.org/0000-0001-8964-5953 und Krüger, Rejko ORCID: https://orcid.org/0000-0003-4258-6241
(2020):
A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson’s disease.
In: Science Translational Medicine, Bd. 12, Nr. 560
ORCID: https://orcid.org/0000-0002-3512-3364; Obermaier, Carolin D. ORCID: https://orcid.org/0000-0001-6653-8215; Hanss, Zoé ORCID: https://orcid.org/0000-0002-3659-3624; Bobbili, Dheeraj R.; Bolognin, Silvia ORCID: https://orcid.org/0000-0002-1399-2999; Glaab, Enrico ORCID: https://orcid.org/0000-0003-3977-7469; Wołyńska, Katarzyna ORCID: https://orcid.org/0000-0002-8377-8496; Weisschuh, Nicole; De Conti, Laura ORCID: https://orcid.org/0000-0003-4391-3638; May, Caroline ORCID: https://orcid.org/0000-0002-6532-5979; Giesert, Florian ORCID: https://orcid.org/0000-0001-6825-8858; Grossmann, Dajana; Lambert, Annika ORCID: https://orcid.org/0000-0003-4503-4266; Kirchen, Susanne ORCID: https://orcid.org/0000-0003-0211-1815; Biryukov, Maria; Burbulla, Lena F. ORCID: https://orcid.org/0000-0002-6548-905X; Massart, Francois ORCID: https://orcid.org/0000-0001-5590-3344; Bohler, Jill; Cruciani, Gérald; Schmid, Benjamin ORCID: https://orcid.org/0000-0002-0028-888X; Kurz-Drexler, Annerose ORCID: https://orcid.org/0000-0001-9108-6994; May, Patrick ORCID: https://orcid.org/0000-0001-8698-3770; Duga, Stefano ORCID: https://orcid.org/0000-0003-3457-1410; Klein, Christine; Schwamborn, Jens C. ORCID: https://orcid.org/0000-0003-4496-0559; Marcus, Katrin ORCID: https://orcid.org/0000-0002-3313-8845; Woitalla, Dirk; Vogt Weisenhorn, Daniela M. ORCID: https://orcid.org/0000-0002-4566-6506; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Baralle, Marco ORCID: https://orcid.org/0000-0002-0417-1013; Krainc, Dimitri ORCID: https://orcid.org/0000-0002-4716-1886; Gasser, Thomas ORCID: https://orcid.org/0000-0002-1069-1146; Wissinger, Bernd ORCID: https://orcid.org/0000-0001-8964-5953 und Krüger, Rejko ORCID: https://orcid.org/0000-0003-4258-6241
(2020):
A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson’s disease.
In: Science Translational Medicine, Bd. 12, Nr. 560
Schriever, Sonja C. ORCID: https://orcid.org/0000-0001-5461-3214; Kabra, Dhiraj G.; Pfuhlmann, Katrin; Baumann, Peter ORCID: https://orcid.org/0000-0002-7009-1580; Baumgart, Emily V.; Nagler, Joachim; Seebacher, Fabian ORCID: https://orcid.org/0000-0003-2211-8723; Harrison, Luke; Irmler, Martin ORCID: https://orcid.org/0000-0003-3169-479X; Kullmann, Stephanie; Corrêa-da-Silva, Felipe ORCID: https://orcid.org/0000-0002-7333-367X; Giesert, Florian; Jain, Ruchi; Schug, Hannah; Castel, Julien; Martinez, Sarah; Wu, Moya; Häring, Hans-Ulrich; de Angelis, Martin Hrabe ORCID: https://orcid.org/0000-0002-7898-2353; Beckers, Johannes ORCID: https://orcid.org/0000-0001-7874-3822; Müller, Timo D. ORCID: https://orcid.org/0000-0002-0624-9339; Stemmer, Kerstin; Wurst, Wolfgang; Rozman, Jan ORCID: https://orcid.org/0000-0002-8035-8904; Nogueiras, Ruben; De Angelis, Meri; Molkentin, Jeffery D. ORCID: https://orcid.org/0000-0002-3558-6529; Krahmer, Natalie; Yi, Chun-Xia ORCID: https://orcid.org/0000-0003-1184-4615; Schmidt, Mathias V.; Luquet, Serge; Heni, Martin ORCID: https://orcid.org/0000-0002-8462-3832; Tschöp, Matthias H. und Pfluger, Paul T. ORCID: https://orcid.org/0000-0002-8118-7588
(2020):
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.
In: Journal of Clinical Investigation, Bd. 130, Nr. 11: S. 6093-6108
ORCID: https://orcid.org/0000-0001-5461-3214; Kabra, Dhiraj G.; Pfuhlmann, Katrin; Baumann, Peter ORCID: https://orcid.org/0000-0002-7009-1580; Baumgart, Emily V.; Nagler, Joachim; Seebacher, Fabian ORCID: https://orcid.org/0000-0003-2211-8723; Harrison, Luke; Irmler, Martin ORCID: https://orcid.org/0000-0003-3169-479X; Kullmann, Stephanie; Corrêa-da-Silva, Felipe ORCID: https://orcid.org/0000-0002-7333-367X; Giesert, Florian; Jain, Ruchi; Schug, Hannah; Castel, Julien; Martinez, Sarah; Wu, Moya; Häring, Hans-Ulrich; de Angelis, Martin Hrabe ORCID: https://orcid.org/0000-0002-7898-2353; Beckers, Johannes ORCID: https://orcid.org/0000-0001-7874-3822; Müller, Timo D. ORCID: https://orcid.org/0000-0002-0624-9339; Stemmer, Kerstin; Wurst, Wolfgang; Rozman, Jan ORCID: https://orcid.org/0000-0002-8035-8904; Nogueiras, Ruben; De Angelis, Meri; Molkentin, Jeffery D. ORCID: https://orcid.org/0000-0002-3558-6529; Krahmer, Natalie; Yi, Chun-Xia ORCID: https://orcid.org/0000-0003-1184-4615; Schmidt, Mathias V.; Luquet, Serge; Heni, Martin ORCID: https://orcid.org/0000-0002-8462-3832; Tschöp, Matthias H. und Pfluger, Paul T. ORCID: https://orcid.org/0000-0002-8118-7588
(2020):
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.
In: Journal of Clinical Investigation, Bd. 130, Nr. 11: S. 6093-6108
2019
Gamm, Matthias von; Schaub, Annalisa; Jones, Alisha N.; Wolf, Christine; Behrens, Gesine; Lichti, Johannes; Essig, Katharina; Macht, Anna; Pircher, Joachim; Ehrlich, Andreas; Davari, Kathrin; Chauhan, Dhruv; Busch, Benjamin; Wurst, Wolfgang; Feederle, Regina; Feuchtinger, Annette; Tschoep, Matthias H.; Friedel, Caroline C.; Hauck, Stefanie M.; Sattler, Michael; Geerlof, Arie; Hornung, Veit; Heissmeyer, Vigo; Schulz, Christian; Heikenwalder, Mathias und Glasmacher, Elke
(2019):
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.
In: Journal of Experimental Medicine, Bd. 216, Nr. 7: S. 1700-1723
[PDF, 6MB]
Rudan Njavro, Jasenka; Klotz, Jakob; Dislich, Bastian; Wanngren, Johanna; Shmueli, Merav D.; Herber, Julia; Kuhn, Peer-Hendrik; Kumar, Rohit; Koeglsperger, Thomas; Conrad, Marcus; Wurst, Wolfgang; Feederle, Regina; Vlachos, Andreas; Michalakis, Stylianos; Jedlicka, Peter; Müller, Stephan A. und Lichtenthaler, Stefan F.
(2019):
Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1.
In: FASEB Journal, Bd. 34, Nr. 2: S. 2465-2482
[PDF, 708kB]
Segal, Joanna; Muelleder, Michael; Krüger, Antje; Adler, Thure; Scholze-Wittler, Manuela; Becker, Lore; Calzada-Wack, Julia; Garrett, Lillian; Hoelter, Sabine M.; Rathkolb, Birgit; Rozman, Jan; Racz, Ildiko; Fischer, Ralf; Busch, Dirk H.; Neff, Frauke; Klingenspor, Martin; Klopstock, Thomas; Grüning, Nana-Maria; Michel, Steve; Lukaszewska-McGreal, Beata; Voigt, Ingo; Hartmann, Ludger; Timmermann, Bernd; Lehrach, Hans; Wolf, Eckhard; Wurst, Wolfgang; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin H.; Schrewe, Heinrich; Yuneva, Mariia und Ralser, Markus
(2019):
Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.
In: Journal of Inherited Metabolic Disease, Bd. 42, Nr. 5: S. 839-849
[PDF, 3MB]
Well, Eva M. van; Bader, Verian; Patra, Maria; Sanchez-Vicente, Ana; Meschede, Jens; Furthmann, Nikolas; Schnack, Cathrin; Blusch, Alina; Longworth, Joseph; Petrasch-Parwez, Elisabeth; Mori, Kohji; Arzberger, Thomas; Truembach, Dietrich; Angersbach, Lena; Showkat, Cathrin; Sehr, Dominik A.; Berlemann, Lena A.; Goldmann, Petra; Clement, Albrecht M.; Behl, Christian; Woerner, Andreas C.; Saft, Carsten; Wurst, Wolfgang; Haass, Christian; Ellrichmann, Gisa; Gold, Ralf; Dittmar, Gunnar; Hipp, Mark S.; Hartl, F. Ulrich; Tatzelt, Jörg und Winklhofer, Konstanze F.
(2019):
A protein quality control pathway regulated by linear ubiquitination.
In: EMBO Journal, Bd. 38, Nr. 9, e100730
[PDF, 2MB]
Blume, Jonas; Zietara, Natalia; Witzlau, Katrin; Liu, Yanshan; Sanchez, Oskar Ortiz; Puchalka, Jacek; Winter, Samantha J.; Kunze-Schumacher, Heike; Saran, Namita; Dueber, Sandra; Roy, Bishnudeo; Weiss, Siegfried; Klein, Christoph; Wurst, Wolfgang; Lyszkiewicz, Marcin und Krüger, Andreas
(2019):
miR-191 modulates B-cell development and targets transcription factors E2A, Foxp1, and Egr1.
In: European Journal of Immunology, Bd. 49, Nr. 1: S. 121-132
Hoellerhage, Matthias; Fussi, Natascha; Roesler, Thomas W.; Wurst, Wolfgang; Behrends, Christian und Höglinger, Guenter U.
(2019):
Multiple molecular pathways stimulating macroautophagy protect from alpha-synuclein-induced toxicity in human neurons.
In: Neuropharmacology, Bd. 149: S. 13-26
Solga, Roxana; Behrens, Juliane; Ziemann, Anja; Riou, Adrien; Berwanger, Carolin; Becker, Lore; Garrett, Lillian; de Angelis, Martin Hrabe; Fischer, Lisa; Coras, Roland; Barkovits, Katalin; Marcus, Katrin; Mahabir, Esther; Eichinger, Ludwig; Schröder, Rolf; Noegel, Angelika A.; Clemen, Christoph S.; Aguilar-Pimentel, Antonio; Schmidt-Weber, Carsten; Klopstock, Thomas; Adler, Thure; Treisel, Irina; Busch, Dirk H.; Moreth, Kristin; Hoelter, Sabine M.; Zimprich, Annemarie; Wurst, Wolfgang; Amarie, Oana; Graw, Jochen; Rozman, Jan; Calzada-Wack, Julia; Racz, Ildiko; Rathkolb, Birgit; Wolf, Eckhard; Oestereicher, Manuela; Miller, Gregor; Lengger, Christoph; Maier, Holger; Stoeger, Claudia; Leuchtenberger, Stefanie; Gallus-Durner, Valerie und Fuchs, Helmut
(2019):
CRN2 binds to TIMP4 and MMP14 and promotes perivascular invasion of glioblastoma cells.
In: European Journal of Cell Biology, Bd. 98, Nr. 5-8, UNSP 151046
Vetrivel, Sharmilee; Tiso, Natascia; Kuegler, Andrea; Irmler, Martin; Horsch, Marion; Beckers, Johannes; Hladik, Daniela; Giesert, Florian; Gailus-Durner, Valerie; Fuchs, Helmut; Sabrautzki, Sibylle; Angelis, Martin Hrabe de; Graw, Jochen; Adler, Thure; Treise, Irina; Busch, Dirk H.; Aguilar-Pimentel, Antonio; Ollert, Markus; Götz, Alexander; Amarie, Oana; Stoeger, Tobias; Schulz, Holger; Becker, Lore; Klopstock, Thomas; Schrewe, Anja; Spielmann, Nadine; Bekeredjian, Raffi; Garrett, Lillian; Hoelter, Sabine M.; Zimprich, Annemarie; Wurst, Wolfgang; Mayer-Kuckuk, Philipp; Hans, Wolfgang; Rozman, Jan; Klingenspor, Martin; Neff, Frauke; Silva-Buttkus, Patricia da; Calzada-Wack, Julia; Racz, Ildiko; Zimmer, Andreas; Rathkolb, Birgit; Wolf, Eckhard; Prehn, Cornelia; Adamski, Jerzy; Oestereicher, Manuela; Miller, Gregor; Steinkamp, Ralph; Lengger, Christoph; Maier, Holger; Stoeger, Claudia und Leuchtenberger, Stefanie
(2019):
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.
In: Experimental Eye Research, Bd. 188, UNSP 107632
[PDF, 7MB]
Fecher, Caroline; Trovo, Laura; Müller, Stephan A.; Snaidero, Nicolas; Wettmarshausen, Jennifer; Heink, Sylvia; Ortiz, Oskar; Wagner, Ingrid; Kühn, Ralf; Hartmann, Jana; Karl, Rosa Maria; Konnerth, Arthur; Korn, Thomas; Wurst, Wolfgang; Merkler, Doron; Lichtenthaler, Stefan F.; Perocchi, Fabiana und Misgeld, Thomas
(2019):
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.
In: Nature Neuroscience, Bd. 22, Nr. 10
Dias, Mariana Castro; Coisne, Caroline; Baden, Pascale; Enzmann, Gaby; Garrett, Lillian; Becker, Lore; Hoelter, Sabine M.; de Angelis, Martin Hrabe; Deutsch, Urban; Engelhardt, Britta; Aguilar-Pimentel, Antonio; Adler, Thure; Busch, Dirk H.; Spielmann, Nadine; Moreth, Kristin; Hans, Wolfgang; Amarie, Oana; Graw, Jochen; Rozman, Jan; Radc, Ildiko; Neff, Frauke; Calzada-Wack, Julia; Rathkolb, Birgit; Wolf, Eckhard; Klopstock, Thomas; Wurst, Wolfgang; Beckers, Johannes; Oestereicher, Manuela; Miller, Gregor; Maier, Holger; Stoeger, Claudia; Leuchtenberger, Stefanie; Gailus-Durner, Valerie und Fuchs, Helmut
(2019):
Claudin-12 is not required for blood-brain barrier tight junction function.
In: Fluids and Barriers of the Cns, Bd. 16, Nr. 1, 30
[PDF, 3MB]
Jensen, Lars R.; Garrett, Lillian; Hoelter, Sabine M.; Rathkolb, Birgit; Racz, Ildiko; Adler, Thure; Prehn, Cornelia; Hans, Wolfgang; Rozman, Jan; Becker, Lore; Aguilar-Pimentel, Juan Antonio; Puk, Oliver; Moreth, Kristin; Dopatka, Monika; Walther, Diego J.; Bohlen und Halbach, Viola von; Rath, Matthias; Delatycki, Martin; Bert, Bettina; Fink, Heidrun; Bluemlein, Katharina; Ralser, Markus; Dijck, Anke van; Kooy, Frank; Stark, Zornitza; Müller, Sabine; Scherthan, Harry; Gecz, Jozef; Wurst, Wolfgang; Wolf, Eckhard; Zimmer, Andreas; Klingenspor, Martin; Graw, Jochen; Klopstock, Thomas; Busch, Dirk; Adamski, Jerzy; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Bohlen und Halbach, Oliver von; Ropers, Hans-Hilger und Kuss, Andreas W.
(2019):
A mouse model for intellectual disability caused by mutations in the X-linked 2 '-O-methyltransferase Ftsj1 gene.
In: Biochimica et Biophysica Acta-Molecular Basis of Disease, Bd. 1865, Nr. 9: S. 2083-2093
Baumann, Peter; Schriever, Sonja C.; Kullmann, Stephanie; Zimprich, Annemarie; Feuchtinger, Annette; Amarie, Oana; Peter, Andreas; Walch, Axel; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin Hrabe; Wurst, Wolfgang; Tschoep, Matthias H.; Heni, Martin; Hoelter, Sabine M. und Pfluger, Paul T.
(2019):
Dusp8 affects hippocampal size and behavior in mice and humans.
In: Scientific Reports, Bd. 9, 19483
[PDF, 1MB]
Funk, Natalja; Munz, Marita; Ott, Thomas; Brockmann, Kathrin; Wenninger-Weinzierl, Andrea; Kuehn, Ralf; Vogt-Weisenhorn, Daniela; Giesert, Florian; Wurst, Wolfgang; Gasser, Thomas und Biskup, Saskia
(2019):
The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4.
In: Scientific Reports, Bd. 9, 4515
[PDF, 2MB]
2018
Heermann, Tamara; Garrett, Lillian; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Graw, Jochen und Holter, Sabine M.
(2018):
Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice.
In: Molecular Neurobiology: S. 1-16
Garrett, Lillian; Becker, Lore; Rozman, Jan; Puk, Oliver; Stoeger, Tobias; Yildirim, Ali Onder; Bohla, Alexander; Eickelberg, Oliver; Hans, Wolfgang; Prehn, Cornelia; Adamski, Jerzy; Klopstock, Thomas; Racz, Ildiko; Zimmer, Andreas; Klingenspor, Martin; Fuchs, Helmut; Gailus-Durner, Valerie; Wurst, Wolfgang; Hrabe de Angelis, Martin; Graw, Jochen und Hölter, Sabine M.
(2018):
Fgf9(Y162C) Mutation Alters Information Processing and Social Memory in Mice.
In: Molecular Neurobiology, Bd. 55, Nr. 6: S. 4580-4595
Andre, Viola; Gaut, Christine; Scheideler, Angelika; Aguilar-Pimentel, Juan A.; Amarie, Oana V.; Becker, Lore; Garrett, Lillian; Hans, Wolfgang; Hölter, Sabine M.; Janik, Dirk; Moreth, Kristin; Neff, Frauke; Östereicher, Manuela; Racz, Ildiko; Rathkolb, Birgit; Rozman, Jan; Bekeredjian, Raffi; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Schmidt-Weber, Carsten; Wolf, Eckhard; Wurst, Wolfgang; Gailus-Durner, Valerie; Brielmeier, Markus; Fuchs, Helmut und Hrabe de Angelis, Martin
(2018):
Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.
In: PLOS Biology 16(4), e2005019 [PDF, 5MB]
In: PLOS Biology 16(4), e2005019 [PDF, 5MB]
Zimprich, Annemarie; Ostereicher, Manuela A.; Becker, Lore; Dirscherl, Petra; Ernst, Luise; Fuchs, Helmut; Gailus-Durner, Valerie; Garrett, Lillian; Giesert, Florian; Glasl, Lisa; Hummel, Angelika; Rozman, Jan; Hrabe de Angelis, Martin; Vogt-Weisenhorn, Daniela; Wurst, Wolfgang und Hölter, Sabine M.
(2018):
Analysis of locomotor behavior in the German Mouse Clinic.
In: Journal of Neuroscience Methods, Bd. 300: S. 77-91
Fuchs, Helmut; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Cho, Yi-Li; Garrett, Lillian; Hölter, Sabine M.; Irmler, Martin; Kistler, Martin; Kraiger, Markus; Mayer-Kuckuk, Philipp; Moreth, Kristin; Rathkolb, Birgit; Rozman, Jan; Silva Buttkus, Patricia da; Treise, Irina; Zimprich, Annemarie; Gampe, Kristine; Hutterer, Christine; Stoeger, Claudia; Leuchtenberger, Stefanie; Maier, Holger; Miller, Manuel; Scheideler, Angelika; Wu, Moya; Beckers, Johannes; Bekeredjian, Raffi; Brielmeier, Markus; Busch, Dirk H.; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Schmidt-Weber, Carsten; Stoeger, Tobias; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Oender; Zimmer, Andreas; Gailus-Durner, Valerie und Hrabe de Angelis, Martin
(2018):
Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.
In: Behavioural Brain Research, Bd. 352: S. 187-196
Xiang, Xianyuan; Piers, Thomas M.; Wefers, Benedikt; Zhu, Kaichuan; Mallach, Anna; Brunner, Bettina; Kleinberger, Gernot; Song, Wilbur; Colonna, Marco; Herms, Jochen; Wurst, Wolfgang; Pocock, Jennifer M. und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2018):
The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
In: Molecular Neurodegeneration
13:49
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-4869-1627
(2018):
The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
In: Molecular Neurodegeneration
13:49
[PDF, 2MB]
Weber, Axel; Schwarz, Sigrid C.; Tost, Jörg; Truembach, Dietrich; Winter, Pia; Busato, Florence; Tacik, Pawel; Windhorst, Anita C.; Fagny, Maud; Arzberger, Thomas; McLean, Catriona; Swieten, John C. van; Schwarz, Johannes; Weisenhorn, Daniela Vogt; Wurst, Wolfgang; Adhikary, Till; Dickson, Dennis W.; Höglinger, Günter U. und Müller, Ulrich
(2018):
Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1.
In: Nature Communications, Bd. 9, 2929
[PDF, 1MB]
Fussi, Natascha; Höllerhage, Matthias; Chakroun, Tasnim; Nykänen, Niko-Petteri; Roesler, Thomas W.; Köglsperger, Thomas; Wurst, Wolfgang; Behrends, Christian und Höglinger, Guenter U.
(2018):
Exosomal secretion of alpha-synuclein as protective mechanism after upstream blockage of macroautophagy.
In: Cell Death & Disease, Bd. 9, 757
[PDF, 1MB]
Schaeffner, Iris; Minakaki, Georgia; Khan, M. Amir; Balta, Elli-Anna; Schloetzer-Schrehardt, Ursula; Schwarz, Tobias J.; Beckervordersandforth, Ruth; Winner, Beate; Webb, Ashley E.; DePinho, Ronald A.; Paik, Jihye; Wurst, Wolfgang; Klucken, Jochen und Lie, D. Chichung
(2018):
FoxO Function Is Essential for Maintenance of Autophagic Flux and Neuronal Morphogenesis in Adult Neurogenesis.
In: Neuron, Bd. 99, Nr. 6: S. 1188-1203
Breunig, Christopher T.; Neuner, Andrea M.; Giehrl-Schwab, Jessica; Wurst, Wolfgang; Götz, Magdalena und Stricker, Stefan H.
(2018):
A Customizable Protocol for String Assembly gRNA Cloning (STAgR).
In: Jove-Journal of Visualized Experiments, Nr. 142, e58556
Vogt, Miriam A.; Ehsaei, Zahra; Knuckles, Philip; Higginbottom, Adrian; Helmbrecht, Michaela S.; Kunath, Tilo; Eggan, Kevin; Williams, Luis A.; Shaw, Pamela J.; Wurst, Wolfgang; Floss, Thomas; Huber, Andrea B. und Taylor, Verdon
(2018):
TDP-43 induces p53-mediated cell death of cortical progenitors and immature neurons.
In: Scientific Reports, Bd. 8, 8097
[PDF, 6MB]
Ingold, Irina; Berndt, Carsten; Schmitt, Sabine; Doll, Sebastian; Poschmann, Gereon; Buday, Katalin; Roveri, Antonella; Peng, Xiaoxiao; Freitas, Florencio Porto; Seibt, Tobias; Mehr, Lisa; Aichler, Michaela; Walch, Axel; Lamp, Daniel; Jastroch, Martin; Miyamoto, Sayuri; Wurst, Wolfgang; Ursini, Fulvio; Amer, Elias S. J.; Fradejas-Villar, Noelia; Schweizer, Ulrich; Zischka, Hans; Angeli, Jose Pedro Friedmann und Conrad, Marcus
(2018):
Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis.
In: Cell, Bd. 172, Nr. 3: S. 409-422
Rozman, Jan; Rathkolb, Birgit; Oestereicher, Manuela A.; Schütt, Christine; Ravindranath, Aakash Chavan; Leuchtenberger, Stefanie; Sharma, Sapna; Kistler, Martin; Willershaeuser, Monja; Brommage, Robert; Meehan, Terrence F.; Mason, Jeremy; Haselimashhadi, Hamed; Hough, Tertius; Mallon, Ann-Marie; Wells, Sara; Santos, Luis; Lelliott, Christopher J.; White, Jacqueline K.; Sorg, Tania; Champy, Marie-France; Bower, Lynette R.; Reynolds, Corey L.; Flenniken, Ann M.; Murray, Stephen A.; Nutter, Lauryl M. J.; Svenson, Karen L.; West, David; Tocchini-Valentini, Glauco P.; Beaudet, Arthur L.; Bosch, Fatima; Braun, Robert B.; Dobbie, Michael S.; Gao, Xiang; Herault, Yann; Moshiri, Ala; Moore, Bret A.; Lloyd, K. C. Kent; McKerlie, Colin; Masuya, Hiroshi; Tanaka, Nobuhiko; Flicek, Paul; Parkinson, Helen E.; Sedlacek, Radislav; Seong, Je Kyung; Wang, Chi-Kuang Leo; Moore, Mark; Brown, Steve D.; Tschoep, Matthias H.; Wurst, Wolfgang; Klingenspor, Martin; Wolf, Eckhard; Beckers, Johannes; Machicao, Fausto; Peter, Andreas; Staiger, Harald; Häring, Hans-Ulrich; Grallert, Harald; Campillos, Monica; Maier, Holger; Fuchs, Helmut; Gailus-Durner, Valerie; Werner, Thomas und Hrabe de Angelis, Martin
(2018):
Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
In: Nature Communications, Bd. 9, 288
[PDF, 2MB]
Myklatun, Ahne; Lauri, Antonella; Eder, Stephan H. K.; Cappetta, Michele; Shcherbakov, Denis; Wurst, Wolfgang; Winklhofer, Michael und Westmeyer, Gil G.
(2018):
Zebrafish and medaka offer insights into the neurobehavioral correlates of vertebrate magnetoreception.
In: Nature Communications, Bd. 9, 802
[PDF, 2MB]
Di Giaimo, Rossella; Durovic, Tamara; Barquin, Pablo; Kociaj, Anita; Lepko, Tjasa; Aschenbroich, Sven; Breunig, Christopher T.; Irmler, Martin; Cernilogar, Filippo M.; Schotta, Gunnar; Barbosa, Joana S.; Trümbach, Dietrich; Baumgart, Emily Violette; Neuner, Andrea M.; Beckers, Johannes; Wurst, Wolfgang; Stricker, Stefan H. und Ninkovic, Jovica
(2018):
The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Restorative Neurogenesis.
In: Cell Reports, Bd. 25, Nr. 12: S. 3241-3251
[PDF, 4MB]
2017
Mazaheri, Fargol; Snaidero, Nicolas; Kleinberger, Gernot; Madore, Charlotte; Daria, Anna; Werner, Georg; Krasemann, Susanne; Capell, Anja; Trümbach, Dietrich; Wurst, Wolfgang; Brunner, Bettina; Bultmann, Sebastian; Tahirovic, Sabina; Kerschensteiner, Martin; Misgeld, Thomas; Butovsky, Oleg und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.
In: Embo Reports, Bd. 18, Nr. 7: S. 1186-1198
ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.
In: Embo Reports, Bd. 18, Nr. 7: S. 1186-1198
Schludi, Martin H.; Becker, Lore; Garrett, Lillian; Gendron, Tania F.; Zhou, Qihui; Schreiber, Franziska; Popper, Bastian; Dimou, Leda; Strom, Tim M.; Winkelmann, Juliane; Thaden, Anne von; Rentzsch, Kristin; May, Stephanie; Michaelsen, Meike; Schwenk, Benjamin M.; Tan, Jing; Schoser, Benedikt; Dieterich, Marianne; Petrucelli, Leonard; Hölter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Klopstock, Thomas; Arzberger, Thomas und Edbauer, Dieter
(2017):
Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss.
In: Acta Neuropathologica, Bd. 134, Nr. 2: S. 241-254
Kleinberger, Gernot; Brendel, Matthias; Mracsko, Eva; Wefers, Benedikt; Groeneweg, Linda; Xiang, Xianyuan; Focke, Carola; Deußing, Maximilian; Suarez-Calvet, Marc; Mazaheri, Fargol; Parhizkar, Samira; Pettkus, Nadine; Wurst, Wolfgang; Feederle, Regina; Bartenstein, Peter; Mueggler, Thomas; Arzberger, Thomas; Knuesel, Irene; Rominger, Axel und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.
In: Embo Journal, Bd. 36, Nr. 13: S. 1837-1853
ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.
In: Embo Journal, Bd. 36, Nr. 13: S. 1837-1853
Metzger, Michael W.; Walser, Sandra M.; Dedic, Nina; Aprile-Garcia, Fernando; Jakubcakova, Vladimira; Adamczyk, Marek; Webb, Katharine J.; Uhr, Manfred; Refojo, Damian; Schmidt, Mathias V.; Friess, Elisabeth; Steiger, Axel; Kimura, Mayumi; Chen, Alon; Holsboer, Florian; Arzt, Eduardo; Wurst, Wolfgang und Deussing, Jan M.
(2017):
Heterozygosity for the Mood Disorder-Associated Variant Gln460Arg Alters P2X7 Receptor Function and Sleep Quality.
In: Journal of Neuroscience, Bd. 37, Nr. 48: S. 11688-11700
Metzger, Michael W.; Walser, Sandra M.; Aprile-Garcia, Fernando; Dedic, Nina; Chen, Alon; Holsbör, Florian; Arzt, Eduardo; Wurst, Wolfgang und Deussing, Jan M.
(2017):
Genetically dissecting P2rx7 expression within the central nervous system using conditional humanized mice.
In: Purinergic Signalling, Bd. 13, Nr. 2: S. 153-170
Deng, Tao; Postnikov, Yuri; Zhang, Shaofei; Garrett, Lillian; Becker, Lore; Racz, Ildiko; Hoelter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin und Bustin, Michael
(2017):
Interplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation.
In: Nucleic Acids Research, Bd. 45, Nr. 6: S. 3031-3045
Zimprich, Annemarie; Mroz, Gabi; Meyer zu Reckendorf, Christopher; Anastasiadou, Sofia; Förstner, Philip; Garrett, Lillian; Hölter, Sabine M.; Becker, Lore; Rozman, Jan; Prehn, Cornelia; Rathkolb, Birgit; Moreth, Kristin; Wurst, Wolfgang; Klopstock, Thomas; Klingenspor, Martin; Adamski, Jerzy; Wolf, Eckhard; Bekeredjian, Raffi; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin und Knöll, Bernd
(2017):
Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms.
In: Molecular Neurobiology, Bd. 54, Nr. 10: S. 8242-8262
Salminen, Aaro V.; Garrett, Lillian; Schormair, Barbara; Rozman, Jan; Giesert, Florian; Niedermeier, Kristina M.; Becker, Lore; Rathkolb, Birgit; Racz, Ildiko; Klingenspor, Martin; Klopstock, Thomas; Wolf, Eckhard; Zimmer, Andreas; Gailus-Durner, Valerie; Torres, Miguel; Fuchs, Helmut; Hrabe de Angelis, Martin; Wurst, Wolfgang; Hölter, Sabine M. und Winkelmann, Juliane
(2017):
Meis1: effects on motor phenotypes and the sensorimotor system in mice.
In: Disease Models & Mechanisms, Bd. 10, Nr. 8: S. 981-991
2016
Wittmann, Anke; Grimm, Marcus O. W.; Scherthan, Harry; Horsch, Marion; Beckers, Johannes; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Ford, Steven J.; Burton, Neal C.; Razansky, Daniel; Trümbach, Dietrich; Aichler, Michaela; Walch, Axel Karl; Calzada-Wack, Julia; Neff, Frauke; Wurst, Wolfgang; Hartmann, Tobias und Floss, Thomas
(2016):
Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice.
In: PLOS ONE 11(10), e0164298 [PDF, 5MB]
In: PLOS ONE 11(10), e0164298 [PDF, 5MB]
Nechiporuk, Tamilla; McGann, James; Mullendorff, Karin; Hsieh, Jenny; Wurst, Wolfgang; Floss, Thomas und Mandel, Gail
(2016):
The REST remodeling complex protects genomic integrity during embryonic neurogenesis.
In: eLife, Bd. 5, e09584
[PDF, 8MB]
Fuchs, Helmut; Sabrautzki, Sibylle; Przemeck, Gerhard K. H.; Leuchtenberger, Stefanie; Lorenz-Depiereux, Bettina; Becker, Lore; Rathkolb, Birgit; Horsch, Marion; Garrett, Lillian; Östereicher, Manuela A.; Hans, Wolfgang; Abe, Koichiro; Sagawa, Nobuho; Rozman, Jan; Vargas-Panesso, Ingrid L.; Sandholzer, Michael; Lisse, Thomas S.; Adler, Thure; Aguilar-Pimentel, Juan Antonio; Calzada-Wack, Julia; Ehrhard, Nicole; Elvert, Ralf; Gau, Christine; Hölter, Sabine M.; Micklich, Katja; Moreth, Kristin; Prehn, Cornelia; Puk, Oliver; Racz, Ildiko; Stoeger, Claudia; Vernaleken, Alexandra; Michel, Dian; Diener, Susanne; Wieland, Thomas; Adamski, Jerzy; Bekeredjian, Raffi; Busch, Dirk H.; Favor, John; Graw, Jochen; Klingenspor, Martin; Lengger, Christoph; Maier, Holger; Neff, Frauke; Ollert, Markus; Stoeger, Tobias; Yildirim, Ali Önder; Strom, Tim M.; Zimmer, Andreas; Wolf, Eckhard; Wurst, Wolfgang; Klopstock, Thomas; Beckers, Johannes; Gailus-Durner, Valerie und Hrabé de Angelis, Martin
(2016):
The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.
In: G3-Genes Genomes Genetics, Bd. 6, Nr. 12: S. 4035-4046
Vogt Weisenhorn, Daniela Maria; Giesert, Florian und Wurst, Wolfgang
(2016):
Diversity matters - heterogeneity of dopaminergic neurons in the ventral mesencephalon and its relation to Parkinson's Disease.
In: Journal of Neurochemistry, Bd. 139: S. 8-26
Sabrautzki, Sibylle; Sandholzer, Michael A.; Lorenz-Depiereux, Bettina; Brommage, Robert; Przemeck, Gerhard; Panesso, Ingrid L. Vargas; Vernaleken, Alexandra; Garrett, Lillian; Baron, Katharina; Yildirim, Ali O.; Rozman, Jan; Rathkolb, Birgit; Gau, Christine; Hans, Wolfgang; Hoelter, Sabine M.; Marschall, Susan; Stoeger, Claudia; Becker, Lore; Fuchs, Helmut; Gailus-Durner, Valerie; Klingenspor, Martin; Klopstock, Thomas; Lengger, Christoph; Stefanie, Leuchtenberger; Wolf, Eckhard; Strom, Tim M.; Wurst, Wolfgang und Hrabě de Angelis, Martin
(2016):
Viable Ednra (Y129F) mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation.
In: Mammalian Genome, Bd. 27, Nr. 11-12: S. 587-598
Klafke, Ruth; Anand, A. Alwin Prem; Wurst, Wolfgang; Prakash, Nilima und Wizenmann, Andrea
(2016):
Differences in the spatiotemporal expression and epistatic gene regulation of the mesodiencephalic dopaminergic precursor marker PITX3 during chicken and mouse development.
In: Development, Bd. 143, Nr. 4: S. 691-702
Wurst, Wolfgang
(2016):
Animal Models Are Valid to Uncover Disease Mechanisms.
In: PLOS Genetics 12(5), e1006013 [PDF, 727kB]
In: PLOS Genetics 12(5), e1006013 [PDF, 727kB]
2015
Bender, Julia; Engeholm, Maik; Ederer, Marion S.; Breu, Johannes; Moller, Thor C.; Michalakis, Stylianos; Rasko, Tamas; Wanker, Erich E.; Biel, Martin; Martinez, Karen L.; Wurst, Wolfgang und Deussing, Jan M.
(2015):
Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif.
In: PLOS ONE 10(9), e0136768 [PDF, 20MB]
In: PLOS ONE 10(9), e0136768 [PDF, 20MB]
Truong, Dong-Jiunn Jeffery; Kuehner, Karin; Kuehn, Ralf; Werfel, Stanislas; Engelhardt, Stefan; Wurst, Wolfgang und Ortiz, Oskar
(2015):
Development of an intein-mediated split-Cas9 system for gene therapy.
In: Nucleic Acids Research, Bd. 43, Nr. 13: S. 6450-6458
[PDF, 4MB]
Brandl, Christina; Ortiz, Oskar; Röttig, Bernhard; Wefers, Benedikt; Wurst, Wolfgang und Kühn, Ralf
(2015):
Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.
In: Febs Open Bio, Bd. 5: S. 26-35
2014
Becker, Lore; Kling, Eva; Schiller, Evelyn; Zeh, Ramona; Schrewe, Anja; Hölter, Sabine M.; Mossbrugger, Ilona; Calzada-Wack, Julia; Strecker, Valentina; Wittig, Ilka; Dumitru, Iulia; Wenz, Tina; Bender, Andreas; Aichler, Michaela; Janik, Dirk; Neff, Frauke; Walch, Axel; Quintanilla-Fend, Leticia; Floss, Thomas; Bekeredjian, Raffi; Gailus-Durner, Valerie; Fuchs, Helmut; Wurst, Wolfgang; Meitinger, Thomas; Prokisch, Holger; Hrabé de Angelis, Martin und Klopstock, Thomas
(2014):
MTO1-Deficient Mouse Model Mirrors the Human Phenotype Showing Complex I Defect and Cardiomyopathy.
In: PLOS ONE 9(12), e114918 [PDF, 1MB]
In: PLOS ONE 9(12), e114918 [PDF, 1MB]
Gewies, Andreas; Gorka, Oliver; Bergmann, Hanna; Pechloff, Konstanze; Petermann, Franziska; Jeltsch, Katharina M.; Rudelius, Martina; Kriegsmann, Mark; Weichert, Wilko; Horsch, Marion; Beckers, Johannes; Wurst, Wolfgang; Heikenwalder, Mathias; Korn, Thomas; Heissmeyer, Vigo und Ruland, Jürgen
(2014):
Uncoupling Malt1 Threshold Function from Paracaspase Activity Results in Destructive Autoimmune Inflammation.
In: Cell Reports, Bd. 9, Nr. 4: S. 1292-1305
[PDF, 4MB]
Matthes, Michaela; Preusse, Martin; Zhang, Jingzhong; Schechter, Julia; Mayer, Daniela; Lentes, Bernd; Theis, Fabian; Prakash, Nilima; Wurst, Wolfgang und Trümbach, Dietrich
(2014):
Mouse IDGenes: a reference database for genetic interactions in the developing mouse brain.
In: Database-The Journal of Biological Databases and Curation, bau083
[PDF, 1MB]
Toyoda, Yusuke; Erkut, Cihan; Pan-Montojo, Francisco; Boland, Sebastian; Stewart, Martin P.; Müller, Daniel J.; Wurst, Wolfgang; Hyman, Anthony A. und Kurzchalia, Teymuras V.
(2014):
Products of the Parkinson's disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival.
In: Biology Open, Bd. 3, Nr. 8: S. 777-784
[PDF, 821kB]
Kraus, Petra; Sivakamasundari, V; Yu, Hong Bing; Xing, Xing; Lim, Siew Lan; Adler, Thure; Pimentel, Juan Antonio Aguilar; Becker, Lore; Bohla, Alexander; Garrett, Lillian; Hans, Wolfgang; Hölter, Sabine M.; Janas, Eva; Moreth, Kristin; Prehn, Cornelia; Puk, Oliver; Rathkolb, Birgit; Rozman, Jan; Adamski, Jerzy; Bekeredjian, Raffi; Busch, Dirk H.; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Neff, Frauke; Ollert, Markus; Stoeger, Tobias; Yildrim, Ali Önder; Eickelberg, Oliver; Wolf, Eckhard; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabě de Angelis, Martin; Lufkin, Thomas und Stanton, Lawrence W.
(2014):
Pleiotropic Functions for Transcription Factor Zscan10.
In: PLOS ONE 9(8), e104568 [PDF, 3MB]
In: PLOS ONE 9(8), e104568 [PDF, 3MB]
Meier, Florian; Giesert, Florian; Delic, Sabit; Faus-Kessler, Theresa; Matheus, Friederike; Simeone, Antonio; Hölter, Sabine M.; Kuehn, Ralf; Weisenhorn, Daniela M. Vogt; Wurst, Wolfgang und Prakash, Nilima
(2014):
FGF/FGFR2 Signaling Regulates the Generation and Correct Positioning of Bergmann Glia Cells in the Developing Mouse Cerebellum.
In: PLOS ONE 9(7), e101124 [PDF, 23MB]
In: PLOS ONE 9(7), e101124 [PDF, 23MB]
Zumbrennen-Bullough, Kimberly B.; Becker, Lore; Garrett, Lillian; Hölter, Sabine M.; Calzada-Wack, Julia; Mossbrugger, Ilona; Quintanilla-Fend, Leticia; Racz, Ildiko; Rathkolb, Birgit; Klopstock, Thomas; Wurst, Wolfgang; Zimmer, Andreas; Wolf, Eckhard; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabé de Angelis, Martin; Romney, Steven J. und Leibold, Elizabeth A.
(2014):
Abnormal Brain Iron Metabolism in Irp2 Deficient Mice Is Associated with Mild Neurological and Behavioral Impairments.
In: PLOS ONE 9(6), e98072 [PDF, 5MB]
In: PLOS ONE 9(6), e98072 [PDF, 5MB]
2012
Olszewski, Pawel K.; Rozman, Jan; Jacobsson, Josefin A.; Rathkolb, Birgit; Stromberg, Siv; Hans, Wolfgang; Klockars, Anica; Alsio, Johan; Riserus, Ulf; Becker, Lore; Hoelter, Sabine M.; Elvert, Ralf; Ehrhardt, Nicole; Gailus-Durner, Valerie; Fuchs, Helmut; Fredriksson, Robert; Wolf, Eckhard; Klopstock, Thomas; Wurst, Wolfgang; Levine, Allen S.; Marcus, Claude; Hrabé de Angelis, Martin; Klingenspor, Martin; Schiöth, Helgi B. und Kilimann, Manfred W.
(März 2012):
Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans.
In: PLOS Genetics 8(3), e1002568. [PDF, 644kB]
In: PLOS Genetics 8(3), e1002568. [PDF, 644kB]
Staropoli, John F.; Haliw, Larissa; Biswas, Sunita; Garrett, Lillian; Hölter, Sabine M.; Becker, Lore; Skosyrski, Sergej; Silva-Buttkus, Patricia da; Calzada-Wack, Julia; Neff, Frauke; Rathkolb, Birgit; Rozman, Jan; Schrewe, Anja; Adler, Thure; Puk, Oliver; Sun, Minxuan; Favor, Jack; Racz, Ildikó; Bekeredjian, Raffi; Busch, Dirk H.; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Wolf, Eckhard; Wurst, Wolfgang; Zimmer, Andreas; Lopez, Edith; Harati, Hayat; Hill, Eric; Krause, Daniela S.; Guide, Jolene; Dragileva, Ella; Gale, Evan; Wheeler, Vanessa C.; Boustany, Rose-Mary; Brown, Diane E.; Breton, Sylvie; Ruether, Klaus; Gailus-Durner, Valérie; Fuchs, Helmut; Hrabé de Angelis, Martin und Cotman, Susan L.
(2012):
Large-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system.
In: PLOS ONE 7(6), e38310 [PDF, 4MB]
In: PLOS ONE 7(6), e38310 [PDF, 4MB]
2010
Zhang, Jingzhong; Giesert, Florian; Kloos, Karina; Weisenhorn, Daniela M. Vogt; Aigner, Ludwig; Wurst, Wolfgang und Couillard-Despres, Sebastien
(2010):
A powerful transgenic tool for fate mapping and functional analysis of newly generated neurons.
In: BMC Neuroscience
11:158
[PDF, 2MB]
2008
Soeker, Torben; Dalke, Claudia; Puk, Oliver; Floss, Thomas; Becker, Lore; Bolle, Ines; Favor, Jack; Hans, Wolfgang; Hoelter, Sabine M.; Horsch, Marion; Kallnik, Magdalena; Kling, Eva; Moerth, Corinna; Schrewe, Anja; Stigloher, Christian; Topp, Stefanie; Gailus-Durner, Valerie; Naton, Beatrix; Beckers, Johannes; Fuchs, Helmut; Ivandic, Boris; Klopstock, Thomas; Schulz, Holger; Wolf, Eckhard; Wurst, Wolfgang; Bally-Cuif, Laure; de Angelis, Martin Hrabe und Graw, Jochen
(2008):
Pleiotropic effects in Eya3 knockout mice.
In: BMC Developmental Biology
8:118
[PDF, 3MB]