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Anzahl der Publikationen: 111

Zeitschriftenartikel

Leu, Chia-Luen; Lam, Daniel D.; Salminen, Aaro; Wefers, Benedikt; Becker, Lore; Garrett, Lillian; Rozman, Jan; Wurst, Wolfgang; de Angelis, Martin Hrabe; Hoelter, Sabine M.; Winkelmann, Juliane und Williams, Rhiannan H. (2024): A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice. In: Sleep, Bd. 47, Nr. 5

Xu, Meng; Ito-Kureha, Taku; Kang, Hyun-Seo; Chernev, Aleksandar; Raj, Timsse; Hoefig, Kai P.; Hohn, Christine; Giesert, Florian; Wang, Yinhu; Pan, Wenliang; Zietara, Natalia; Straub, Tobias; Feederle, Regina; Daniel, Carolin; Adler, Barbara; Koenig, Julian; Feske, Stefan; Tsokos, George C.; Wurst, Wolfgang; Urlaub, Henning; Sattler, Michael; Kisielow, Jan; Wulczyn, F. Gregory; Lyszkiewicz, Marcin und Heissmeyer, Vigo (2024): The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression. In: Nature Communications, Bd. 15, Nr. 1, 2194 [PDF, 7MB]

Hembach, Sina; Schmidt, Sebastian; Orschmann, Tanja; Burtscher, Ingo; Lickert, Heiko; Giesert, Florian; Weisenhorn, Daniela Vogt und Wurst, Wolfgang (2024): Engrailed 1 deficiency induces changes in ciliogenesis during human neuronal differentiation. In: Neurobiology of Disease, Bd. 194, 106474 [PDF, 12MB]

Giusti, Sebastian A. ORCID logoORCID: https://orcid.org/0000-0002-0257-3027; Pino, Natalia S. ORCID logoORCID: https://orcid.org/0009-0001-6984-1751; Pannunzio, Camila; Ogando, Mora B. ORCID logoORCID: https://orcid.org/0000-0002-1453-2628; Armando, Natalia G. ORCID logoORCID: https://orcid.org/0000-0003-1379-4025; Garrett, Lillian ORCID logoORCID: https://orcid.org/0000-0003-4880-7076; Zimprich, Annemarie ORCID logoORCID: https://orcid.org/0000-0003-2078-6779; Becker, Lore ORCID logoORCID: https://orcid.org/0000-0002-6890-4984; Gimeno, Maria L.; Lukin, Jeronimo ORCID logoORCID: https://orcid.org/0000-0002-2284-7152; Merino, Florencia L. ORCID logoORCID: https://orcid.org/0000-0001-7247-2750; Pardi, M. Belen ORCID logoORCID: https://orcid.org/0000-0003-1942-7533; Pedroncini, Olivia ORCID logoORCID: https://orcid.org/0009-0009-0613-4126; Di Mauro, Giuliana C. ORCID logoORCID: https://orcid.org/0000-0001-5685-090X; Durner, Valerie Gailus; Fuchs, Helmut; Hrabe de Angelis, Martin ORCID logoORCID: https://orcid.org/0000-0002-7898-2353; Patop, Ines L. ORCID logoORCID: https://orcid.org/0000-0002-2929-0860; Turck, Christoph W. ORCID logoORCID: https://orcid.org/0000-0002-6585-8636; Deussing, Jan M. ORCID logoORCID: https://orcid.org/0000-0002-9329-5252; Vogt Weisenhorn, Daniela M. ORCID logoORCID: https://orcid.org/0000-0002-4566-6506; Jahn, Olaf ORCID logoORCID: https://orcid.org/0000-0002-3397-8924; Kadener, Sebastian; Hölter, Sabine M. ORCID logoORCID: https://orcid.org/0000-0003-4878-5241; Brose, Nils ORCID logoORCID: https://orcid.org/0000-0003-0938-8534; Giesert, Florian ORCID logoORCID: https://orcid.org/0000-0001-6825-8858; Wurst, Wolfgang ORCID logoORCID: https://orcid.org/0000-0003-4422-7410; Marin-Burgin, Antonia ORCID logoORCID: https://orcid.org/0000-0003-0684-9796 und Refojo, Damian ORCID logoORCID: https://orcid.org/0000-0002-9798-6413 (2024): A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuli. In: Science Advances, Bd. 10, Nr. 21 [PDF, 5MB]

Stroo, Esther; Janssen, Leen; Sin, Olga; Hogewerf, Wytse; Koster, Mirjam; Harkema, Liesbeth; Youssef, Sameh A.; Beschorner, Natalie; Wolters, Anouk H. G.; Bakker, Bjorn; Becker, Lore; Garrett, Lilian; Marschall, Susan; Hoelter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Thathiah, Amanth; Foijer, Floris; Sluis, Bart van de; Deursen, Jan van; Jucker, Matthias; Brun, Alain de und Nollen, Ellen A. A. (2023): Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain. In: Life Science Alliance, Bd. 6, Nr. 7, e202201730 [PDF, 2MB]

Schmidt, Henrik; Raj, Timsse; O'Neill, Thomas J.; Muschaweckh, Andreas; Giesert, Florian; Negraschus, Arlinda; Hoefig, Kai P.; Behrens, Gesine; Esser, Lena; Baumann, Christina; Feederle, Regina; Plaza-Sirvent, Carlos; Geerlof, Arie; Gewies, Andreas; Isay, Sophie E.; Ruland, Juergen; Schmitz, Ingo; Wurst, Wolfgang; Korn, Thomas; Krappmann, Daniel und Heissmeyer, Vigo (2023): Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 120, Nr. 48, e2309205120 [PDF, 2MB]

Schmidt, Sebastian; Stautner, Constantin; Vu, Duc Tung; Heinz, Alexander; Regensburger, Martin; Karayel, Ozge; Truembach, Dietrich; Artati, Anna; Kaltenhaeuser, Sabine; Nassef, Mohamed Zakaria; Hembach, Sina; Steinert, Letyfee; Winner, Beate; Juergen, Winkler; Jastroch, Martin; Luecken, Malte D.; Theis, Fabian J.; Westmeyer, Gil Gregor; Adamski, Jerzy; Mann, Matthias; Hiller, Karsten; Giesert, Florian; Weisenhorn, Daniela M. Vogt und Wurst, Wolfgang (2023): A reversible state of hypometabolism in a human cellular model of sporadic Parkinson's disease. In: Nature Communications, Bd. 14, Nr. 1, 7674 [PDF, 7MB]

Gonzalez-Garcia, Ismael; Garcia-Clave, Elena; Cebrian-Serrano, Alberto; Le Thuc, Ophlia; Contreras, Raian E.; Xu, Yanjun; Gruber, Tim; Schriever, Sonja C.; Legutko, Beata; Lintelmann, Jutta; Adamski, Jerzy; Wurst, Wolfgang; Mueller, Timo D.; Woods, Stephen C.; Pfluger, Paul T.; Tschoep, Matthias H.; Fisette, Alexandre und Garcia-Caceres, Cristina (2023): Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1. In: Cell Metabolism, Bd. 35, Nr. 3: 438-+ [PDF, 6MB]

Dening, Yanina; Straßl, Theresa; Ruf, Viktoria; Dirscherl, Petra; Chovsepian, Alexandra; Stievenard, Alicia; Khairnar, Amit; Schmidt, Felix; Giesert, Florian; Herms, Jochen; Levin, Johannes; Dieterich, Marianne; Falkai, Peter; Weisenhorn, Daniela Vogt; Wurst, Wolfgang; Giese, Armin und Pan-Montojo, Francisco (19. Dezember 2022): Toxicity of extracellular alpha-synuclein is independent of intracellular alpha-synuclein. In: Scientific Reports, Bd. 12, Nr. 1 [PDF, 9MB]

Stafford, Che A.; Gassauer, Alicia-Marie; Oliveira Mann, Carina C. de; Tanzer, Maria C. ORCID logoORCID: https://orcid.org/0000-0002-4657-9869; Fessler, Evelyn; Wefers, Benedikt ORCID logoORCID: https://orcid.org/0000-0002-2492-9389; Nagl, Dennis; Kuut, Gunnar; Sulek, Karolina; Vasilopoulou, Catherine; Schwojer, Sophia J. ORCID logoORCID: https://orcid.org/0000-0002-1747-4144; Wiest, Andreas ORCID logoORCID: https://orcid.org/0000-0003-2525-6304; Pfautsch, Marie K.; Wurst, Wolfgang ORCID logoORCID: https://orcid.org/0000-0003-4422-7410; Yabal, Monica ORCID logoORCID: https://orcid.org/0000-0003-3495-7671; Fröhlich, Thomas ORCID logoORCID: https://orcid.org/0000-0002-4709-3211; Mann, Matthias ORCID logoORCID: https://orcid.org/0000-0003-1292-4799; Gisch, Nicolas ORCID logoORCID: https://orcid.org/0000-0003-3260-5269; Jae, Lucas T. ORCID logoORCID: https://orcid.org/0000-0002-3531-1760 und Hornung, Veit ORCID logoORCID: https://orcid.org/0000-0002-4150-194X (2022): Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation. In: Nature, Bd. 609: S. 590-596 [PDF, 10MB]

Stirm, Michael; Fonteyne, Lina Marie; Shashikadze, Bachuki; Stoeckl, Jan B.; Kurome, Mayuko; Kessler, Barbara; Zakhartchenko, Valeri; Kemter, Elisabeth; Blum, Helmut; Arnold, Georg J.; Matiasek, Kaspar; Wanke, Ruediger; Wurst, Wolfgang; Nagashima, Hiroshi; Knieling, Ferdinand; Walter, Maggie C.; Kupatt, Christian; Froehlich, Thomas; Klymiuk, Nikolai; Blutke, Andreas und Wolf, Eckhard (2022): Pig models for Duchenne muscular dystrophy-from disease mechanisms to validation of new diagnostic and therapeutic concepts. In: Neuromuscular Disorders, Bd. 32, Nr. 7: S. 543-556

Garrett, Lillian; Truembach, Dietrich; Spielmann, Nadine; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; De Angelis, Martin Hrabe und Hoelter, Sabine M. (2022): A rationale for considering heart/brain axis control in neuropsychiatric disease. In: Mammalian Genome, Bd. 34, Nr. 2: S. 331-350 [PDF, 7MB]

Vetrivel, Sharmilee; Truong, Dong-Jiunn Jeffery; Wurst, Wolfgang; Graw, Jochen und Giesert, Florian (2022): Identification of ocular regulatory functions of core histone variant H3.2. In: Experimental Eye Research, Bd. 226, 109346

Schmidt, Sebastian; Luecken, Malte D.; Truembach, Dietrich; Hembach, Sina; Niedermeier, Kristina M.; Wenck, Nicole; Pfluegler, Klaus; Stautner, Constantin; Boettcher, Anika; Lickert, Heiko; Ramirez-Suastegui, Ciro; Ahmad, Ruhel; Ziller, Michael J.; Fitzgerald, Julia C.; Ruf, Viktoria; Berg, Wilma D. J. van de; Jonker, Allert J.; Gasser, Thomas; Winner, Beate; Winkler, Juergen; Weisenhorn, Daniela M. Vogt; Giesert, Florian; Theis, Fabian J. und Wurst, Wolfgang (2022): Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease. In: Nature Communications, Bd. 13, Nr. 1, 4819 [PDF, 5MB]

Garrett, Lillian; Da Silva-Buttkus, Patricia; Rathkolb, Birgit; Gerlini, Raffaele; Becker, Lore; Sanz-Moreno, Adrian; Seisenberger, Claudia; Zimprich, Annemarie; Aguilar-Pimentel, Antonio; Amarie, Oana V.; Cho, Yi-Li; Kraiger, Markus; Spielmann, Nadine; Calzada-Wack, Julia; Marschall, Susan; Busch, Dirk; Schmitt-Weber, Carsten; Wolf, Eckhard; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hoelter, Sabine M. und de Angelis, Martin Hrabe (2022): Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk. In: Disease Models & Mechanisms, Bd. 15, Nr. 3, dmm049205 [PDF, 2MB]

Giehrl-Schwab, Jessica; Giesert, Florian; Rauser, Benedict; Lao, Chu Lan; Hembach, Sina; Lefort, Sandrine; Ibarra, Ignacio L.; Koupourtidou, Christina; Luecken, Malte Daniel; Truong, Dong-Jiunn Jeffery; Fischer-Sternjak, Judith; Masserdotti, Giacomo; Prakash, Nilima; Ninkovic, Jovica; Hoelter, Sabine M.; Weisenhorn, Daniela M. Vogt; Theis, Fabian J.; Goetz, Magdalena und Wurst, Wolfgang (2022): Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons. In: EMBO Molecular Medicine, Bd. 14, Nr. 5, e14797 [PDF, 3MB]

Falkai, Peter; Koutsouleris, Nikolaos; Bertsch, Katja; Bialas, Mirko; Binder, Elisabeth; Buehner, Markus; Buyx, Alena; Cai, Na; Cappello, Silvia; Ehring, Thomas; Gensichen, Jochen; Hamann, Johannes; Hasan, Alkomiet; Henningsen, Peter; Leucht, Stefan; Moehrmann, Karl Heinz; Nagelstutz, Elisabeth; Padberg, Frank; Peters, Annette; Pfaeffel, Lea; Reich-Erkelenz, Daniela; Riedl, Valentin; Rueckert, Daniel; Schmitt, Andrea; Schulte-Koerne, Gerd; Scheuring, Elfriede; Schulze, Thomas G.; Starzengruber, Rudolf; Stier, Susanne; Theis, Fabian J.; Winkelmann, Juliane; Wurst, Wolfgang und Priller, Josef (2022): Concept of the Munich/Augsburg Consortium Precision in Mental Health for the German Center of Mental Health. In: Frontiers in Psychiatry, Bd. 13, 815718

Sanchez-Gonzalez, Rosario; Koupourtidou, Christina; Lepko, Tjasa; Zambusi, Alessandro; Novoselc, Klara Tereza; Durovic, Tamara; Aschenbroich, Sven; Schwarz, Veronika; Breunig, Christopher T.; Straka, Hans; Huttner, Hagen B.; Irmler, Martin; Beckers, Johannes; Wurst, Wolfgang; Zwergal, Andreas; Schauer, Tamas; Straub, Tobias; Czopka, Tim; Trümbach, Dietrich; Götz, Magdalena; Stricker, Stefan H. und Ninkovic, Jovica (2022): Innate Immune Pathways Promote Oligodendrocyte Progenitor Cell Recruitment to the Injury Site in Adult Zebrafish Brain. In: Cells, Bd. 11, Nr. 3, 520 [PDF, 9MB]

Xie, Kan; Fuchs, Helmut; Scifo, Enzo; Liu, Dan; Aziz, Ahmad; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; da Silva-Buttkus, Patricia; Calzada-Wack, Julia; Cho, Yi-Li; Deng, Yushuang; Edwards, A. Cole; Garrett, Lillian; Georgopoulou, Christina; Gerlini, Raffaele; Hoelter, Sabine M.; Klein-Rodewald, Tanja; Kramer, Michael; Leuchtenberger, Stefanie; Lountzi, Dimitra; Mayer-Kuckuk, Phillip; Nover, Lena L.; Oestereicher, Manuela A.; Overkott, Clemens; Pearson, Brandon L.; Rathkolb, Birgit; Rozman, Jan; Russ, Jenny; Schaaf, Kristina; Spielmann, Nadine; Sanz-Moreno, Adrian; Stoeger, Claudia; Treise, Irina; Bano, Daniele; Busch, Dirk H.; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Mock, Beverly A.; Salomoni, Paolo; Schmidt-Weber, Carsten; Weiergraber, Marco; Wolf, Eckhard; Wurst, Wolfgang; Gailus-Durner, Valerie; Breteler, Monique M. B.; Hrabe de Angelis, Martin und Ehninger, Dan (2022): Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice. In: Nature Communications, Bd. 13, Nr. 1, 6830 [PDF, 7MB]

Maity-Kumar, Gandhari; Staender, Lisa; DeAngelis, Meri; Lee, Sooyeon; Molenaar, Anna; Becker, Lore; Garrett, Lillian; Amerie, Oana; Hoelter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Feuchtinger, Annette; Gailus-Durner, Valerie; Gárcia-Cáceres, Cristina; Othman, Ahmed E.; Brockmann, Caroline; Schoeffling, Vanessa I.; Beiser, Katja; Krude, Heiko; Mroz, Piotr A.; Hofmann, Susanna; Tuckermann, Jan; DiMarchi, Richard D.; de Angelis, Martin Hrabe; Tschoep, Matthias H.; Pfluger, Paul T. und Mueller, Timo D. (2022): Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome. In: Molecular Metabolism, Bd. 66, 101616 [PDF, 3MB]

Danileviciute, Egle; Zeng, Ni; Capelle, Christophe M.; Paczia, Nicole; Gillespie, Mark A.; Kurniawan, Henry; Benzarti, Mohaned; Merz, Myriam P.; Coowar, Djalil; Fritah, Sabrina; Weisenhorn, Daniela Maria Vogt; Giro, Gemma Gomez; Grusdat, Melanie; Baron, Alexandre; Guerin, Coralie; Franchina, Davide G.; Leonard, Cathy; Domingues, Olivia; Delhalle, Sylvie; Wurst, Wolfgang; Turner, Jonathan D.; Schwamborn, Jens Christian; Meiser, Johannes; Krueger, Rejko; Ranish, Jeff; Brenner, Dirk; Linster, Carole L.; Balling, Rudi; Ollert, Markus und Hefeng, Feng Q. (2022): PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis during ageing. In: Nature Metabolism, Bd. 4, Nr. 5: 589-+

Schmidt, Sebastian; Weisenhorn, Daniela M. Vogt und Wurst, Wolfgang (2022): Chapter 5-Parkinson's disease - A role of non-enzymatic posttranslational modifications in disease onset and progression? In: Molecular Aspects of Medicine, Bd. 86, 101096 [PDF, 2MB]

Behrens, Gesine; Edelmann, Stephanie L.; Raj, Timsse; Kronbeck, Nina; Monecke, Thomas; Davydova, Elena; Wong, Elaine H.; Kifinger, Lisa; Giesert, Florian; Kirmaier, Martin E.; Hohn, Christine; de Jonge, Laura S.; Pisfil, Mariano Gonzalez; Fu, Mingui; Theurich, Sebastian; Feske, Stefan; Kawakami, Naoto; Wurst, Wolfgang; Niessing, Dierk und Heissmeyer, Vigo (2021): Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses. In: Nature Immunology, Bd. 22, Nr. 12: S. 1563-1576

Biagosch, Caroline A.; Vidali, Silvia; Faerberboeck, Michael; Hensler, Svenja-Viola; Becker, Lore; Amarie, Oana V.; Aguilar-Pimentel, Antonio; Garrett, Lillian; Klein-Rodewald, Tanja; Rathkolb, Birgit; Zanuttigh, Enrica; Calzada-Wack, Julia; Silva-Buttkus, Patricia da; Rozman, Jan; Treise, Irina; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Janik, Dirk; Wurst, Wolfgang; Mayr, Johannes A.; Klopstock, Thomas; Meitinger, Thomas; Prokisch, Holger und Iuso, Arcangela (2021): A comprehensive phenotypic characterization of a whole-body Wdr45 knock-out mouse. In: Mammalian Genome, Bd. 32, Nr. 5: S. 332-349 [PDF, 3MB]

Frey, Laura; Zietara, Natalia; Lyszkiewicz, Marcin; Marquardt, Benjamin; Mizoguchi, Yoko; Linder, Monika I.; Liu, Yanshan; Giesert, Florian; Wurst, Wolfgang; Dahlhoff, Maik; Schneider, Marlon R.; Wolf, Eckhard; Somech, Raz und Klein, Christoph (2021): Mammalian VPS45 orchestrates trafficking through the endosomal system. In: Blood, Bd. 137, Nr. 14: S. 1932-1944

Hansen, Jens; Melchner, Harald von und Wurst, Wolfgang (2021): Mutant non-coding RNA resource in mouse embryonic stem cells. In: Disease Models & Mechanisms, Bd. 14, Nr. 2, dmm047803 [PDF, 719kB]

Kupatt, Christian; Windisch, Alina; Moretti, Alessandra; Wolf, Eckhard; Wurst, Wolfgang und Walter, Maggie C. (2021): Genome editing for Duchenne muscular dystrophy: a glimpse of the future? In: Gene Therapy, Bd. 28, Nr. 9: S. 542-548 [PDF, 904kB]

O'Neill, Thomas J.; Seeholzer, Thomas; Gewies, Andreas; Gehring, Torben; Giesert, Florian; Hamp, Isabel; Grass, Carina; Schmidt, Henrik; Kriegsmann, Katharina; Tofaute, Marie J.; Demski, Katrin; Poth, Tanja; Rosenbaum, Marc; Schnalzger, Theresa; Ruland, Jürgen; Goettlicher, Martin; Kriegsmann, Mark; Naumann, Ronald; Heissmeyer, Vigo; Plettenburg, Oliver; Wurst, Wolfgang und Krappmann, Daniel (2021): TRAF6 prevents fatal inflammation by homeostatic suppression of MALT1 protease. In: Science Immunology, Bd. 6, Nr. 65, eabh2095

Russo, Gianluca L.; Sonsalla, Giovanna; Natarajan, Poornemaa; Breunig, Christopher T.; Bulli, Giorgia; Merl-Pham, Juliane; Schmitt, Sabine; Giehrl-Schwab, Jessica; Giesert, Florian; Jastroch, Martin; Zischka, Hans; Wurst, Wolfgang; Stricker, Stefan H.; Hauck, Stefanie M.; Masserdotti, Giacomo und Goetz, Magdalena (2021): CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion. In: Cell Stem Cell, Bd. 28, Nr. 3: S. 524-534 [PDF, 4MB]

Schaenzer, Anne; Achleitner, Melanie T.; Truembach, Dietrich; Hubert, Laurence; Munnich, Arnold; Ahlemeyer, Barbara; AlAbdulrahim, Maha M.; Greif, Philipp A.; Vosberg, Sebastian; Hummer, Blake; Feichtinger, Rene G.; Mayr, Johannes A.; Wortmann, Saskia B.; Aichner, Heidi; Rudnik-Schoeneborn, Sabine; Ruiz, Anna; Gabau, Elisabeth; Sanchez, Jacobo Perez; Ellard, Sian; Homfray, Tessa; Stals, Karen L.; Wurst, Wolfgang; Neubauer, Bernd A.; Acker, Till; Bohlander, Stefan K.; Asensio, Cedric; Besmond, Claude; Alkuraya, Fowzan S.; AlSayed, Moenaldeen D.; Hahn, Andreas und Weber, Axel (2021): Mutations in HID1 Cause Syndromic Infantile Encephalopathy and Hypopituitarism. In: Annals of Neurology, Bd. 90, Nr. 1: S. 143-158 [PDF, 7MB]

Vidali, Silvia; Gerlini, Raffaele; Thompson, Kyle; Urquhart, Jill E.; Meisterknecht, Jana; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Breen, Catherine; Calzada-Wack, Julia; Chhabra, Nirav F.; Cho, Yi-Li; Silva-Buttkus, Patricia da; Feichtinger, Rene G.; Gampe, Kristine; Garrett, Lillian; Hoefig, Kai P.; Hoelter, Sabine M.; Jameson, Elisabeth; Klein-Rodewald, Tanja; Leuchtenberger, Stefanie; Marschall, Susan; Mayer-Kuckuk, Philipp; Miller, Gregor; Oestereicher, Manuela A.; Pfannes, Kristina; Rathkolb, Birgit; Rozman, Jan; Sanders, Charlotte; Spielmann, Nadine; Stoeger, Claudia; Szibor, Marten; Treise, Irina; Walter, John H.; Wurst, Wolfgang; Mayr, Johannes A.; Fuchs, Helmut; Gaertner, Ulrich; Wittig, Ilka; Taylor, Robert W.; Newman, William G.; Prokisch, Holger; Gailus-Durner, Valerie und Hrabe de Angelis, Martin (2021): Characterising a homozygous two-exon deletion in UQCRH: comparing human and mouse phenotypes. In: EMBO Molecular Medicine, Bd. 13, Nr. 12, e14397

Weisheit, Isabel; Kroeger, Joseph A.; Malik, Rainer; Wefers, Benedikt; Lichtner, Peter; Wurst, Wolfgang; Dichgans, Martin ORCID logoORCID: https://orcid.org/0000-0002-0654-387X und Paquet, Dominik (2021): Simple and reliable detection of CRISPR-induced on-target effects by qgPCR and SNP genotyping. In: Nature Protocols, Bd. 16, Nr. 3: S. 1714-1739

Findeiss, Elisabeth; Schwarz, Sigrid C.; Evsyukov, Valentin; Roesler, Thomas W.; Hoellerhage, Matthias; Chakroun, Tasnim; Nykaenen, Niko-Petteri; Shen, Yimin; Wurst, Wolfgang; Kohl, Michael; Tost, Joerg und Hoeglinger, Guenter U. (2021): Comprehensive miRNome-Wide Profiling in a Neuronal Cell Model of Synucleinopathy Implies Involvement of Cell Cycle Genes. In: Frontiers in Cell and Developmental Biology, Bd. 9, 561086 [PDF, 5MB]

Hsia, Hung-En; Tueshaus, Johanna; Feng, Xiao; Hofmann, Laura; Wefers, Benedikt; Marciano, Denise K.; Wurst, Wolfgang und Lichtenthaler, Stefan F. (2021): Endoglycan (PODXL2) is proteolytically processed by ADAM10 (a disintegrin and metalloprotease 10) and controls neurite branching in primary neurons. In: Faseb Journal, Bd. 35, Nr. 9, e21813 [PDF, 1MB]

Ung, Marie-Claire; Garrett, Lillian; Dalke, Claudia; Leitner, Valentin; Dragosa, Daniel; Hladik, Daniela; Neff, Frauke; Wagner, Florian; Zitzelsberger, Horst; Miller, Gregor; de Angelis, Martin Hrabe; Roessler, Ute; Vogt Weisenhorn, Daniela; Wurst, Wolfgang; Graw, Jochen und Hoelter, Sabine M. (2021): Dose-dependent long-term effects of a single radiation event on behaviour and glial cells. In: International Journal of Radiation Biology, Bd. 97, Nr. 2: S. 156-169 [PDF, 3MB]

Brandes, Ralf P.; Dueck, Anne; Engelhardt, Stefan; Kaulich, Manuel; Kupatt, Christian; De Angelis, Maria Teresa; Leisegang, Matthias S.; le Noble, Ferdinand; Moretti, Alessandra; Mueller, Oliver J.; Skryabin, Boris V.; Thum, Thomas und Wurst, Wolfgang (2021): DGK and DZHK position paper on genome editing: basic science applications and future perspective. In: Basic Research in Cardiology, Bd. 116, Nr. 1, 2 [PDF, 2MB]

Baumann, Peter; Schriever, Sonja C.; Kullmann, Stephanie; Zimprich, Annemarie; Peter, Andreas; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Wurst, Wolfgang; Tschoep, Matthias H.; Heni, Martin; Hoelter, Sabine M. und Pfluger, Paul T. (2021): Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans. In: Brain and Behavior, Bd. 11, Nr. 1, e01928 [PDF, 705kB]

Kollmus, Heike; Fuchs, Helmut; Lengger, Christoph; Haselimashhadi, Hamed; Bogue, Molly A.; Ostereicher, Manuela A.; Horsch, Marion; Adler, Thure; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; Beckers, Johannes; Calzada-Wack, Julia; Garrett, Lillian; Hans, Wolfgang; Hoelter, Sabine M.; Klein-Rodewald, Tanja; Maier, Holger; Mayer-Kuckuk, Philipp; Miller, Gregor; Moreth, Kristin; Neff, Frauke; Rathkolb, Birgit; Racz, Ildiko; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Busch, Dirk; Graw, Jochen; Klopstock, Thomas; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Onder; Mason, Jeremy; Torres, Arturo; Balling, Rudi; Mehaan, Terry; Gailus-Durner, Valerie; Schughart, Klaus und de Angelis, Martin Hrabe (2020): A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes. In: Mammalian Genome, Bd. 31: S. 30-48 [PDF, 3MB]

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Breunig, Christopher T.; Neuner, Andrea M.; Giehrl-Schwab, Jessica; Wurst, Wolfgang; Götz, Magdalena und Stricker, Stefan H. (2018): A Customizable Protocol for String Assembly gRNA Cloning (STAgR). In: Jove-Journal of Visualized Experiments, Nr. 142, e58556

Vogt, Miriam A.; Ehsaei, Zahra; Knuckles, Philip; Higginbottom, Adrian; Helmbrecht, Michaela S.; Kunath, Tilo; Eggan, Kevin; Williams, Luis A.; Shaw, Pamela J.; Wurst, Wolfgang; Floss, Thomas; Huber, Andrea B. und Taylor, Verdon (2018): TDP-43 induces p53-mediated cell death of cortical progenitors and immature neurons. In: Scientific Reports, Bd. 8, 8097 [PDF, 6MB]

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Myklatun, Ahne; Lauri, Antonella; Eder, Stephan H. K.; Cappetta, Michele; Shcherbakov, Denis; Wurst, Wolfgang; Winklhofer, Michael und Westmeyer, Gil G. (2018): Zebrafish and medaka offer insights into the neurobehavioral correlates of vertebrate magnetoreception. In: Nature Communications, Bd. 9, 802 [PDF, 2MB]

Di Giaimo, Rossella; Durovic, Tamara; Barquin, Pablo; Kociaj, Anita; Lepko, Tjasa; Aschenbroich, Sven; Breunig, Christopher T.; Irmler, Martin; Cernilogar, Filippo M.; Schotta, Gunnar; Barbosa, Joana S.; Trümbach, Dietrich; Baumgart, Emily Violette; Neuner, Andrea M.; Beckers, Johannes; Wurst, Wolfgang; Stricker, Stefan H. und Ninkovic, Jovica (2018): The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Restorative Neurogenesis. In: Cell Reports, Bd. 25, Nr. 12: S. 3241-3251 [PDF, 4MB]

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Schludi, Martin H.; Becker, Lore; Garrett, Lillian; Gendron, Tania F.; Zhou, Qihui; Schreiber, Franziska; Popper, Bastian; Dimou, Leda; Strom, Tim M.; Winkelmann, Juliane; Thaden, Anne von; Rentzsch, Kristin; May, Stephanie; Michaelsen, Meike; Schwenk, Benjamin M.; Tan, Jing; Schoser, Benedikt; Dieterich, Marianne; Petrucelli, Leonard; Hölter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Klopstock, Thomas; Arzberger, Thomas und Edbauer, Dieter (2017): Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss. In: Acta Neuropathologica, Bd. 134, Nr. 2: S. 241-254

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Deng, Tao; Postnikov, Yuri; Zhang, Shaofei; Garrett, Lillian; Becker, Lore; Racz, Ildiko; Hoelter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin und Bustin, Michael (2017): Interplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation. In: Nucleic Acids Research, Bd. 45, Nr. 6: S. 3031-3045

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Salminen, Aaro V.; Garrett, Lillian; Schormair, Barbara; Rozman, Jan; Giesert, Florian; Niedermeier, Kristina M.; Becker, Lore; Rathkolb, Birgit; Racz, Ildiko; Klingenspor, Martin; Klopstock, Thomas; Wolf, Eckhard; Zimmer, Andreas; Gailus-Durner, Valerie; Torres, Miguel; Fuchs, Helmut; Hrabe de Angelis, Martin; Wurst, Wolfgang; Hölter, Sabine M. und Winkelmann, Juliane (2017): Meis1: effects on motor phenotypes and the sensorimotor system in mice. In: Disease Models & Mechanisms, Bd. 10, Nr. 8: S. 981-991

Wittmann, Anke; Grimm, Marcus O. W.; Scherthan, Harry; Horsch, Marion; Beckers, Johannes; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Ford, Steven J.; Burton, Neal C.; Razansky, Daniel; Trümbach, Dietrich; Aichler, Michaela; Walch, Axel Karl; Calzada-Wack, Julia; Neff, Frauke; Wurst, Wolfgang; Hartmann, Tobias und Floss, Thomas (2016): Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice.
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Vogt Weisenhorn, Daniela Maria; Giesert, Florian und Wurst, Wolfgang (2016): Diversity matters - heterogeneity of dopaminergic neurons in the ventral mesencephalon and its relation to Parkinson's Disease. In: Journal of Neurochemistry, Bd. 139: S. 8-26

Sabrautzki, Sibylle; Sandholzer, Michael A.; Lorenz-Depiereux, Bettina; Brommage, Robert; Przemeck, Gerhard; Panesso, Ingrid L. Vargas; Vernaleken, Alexandra; Garrett, Lillian; Baron, Katharina; Yildirim, Ali O.; Rozman, Jan; Rathkolb, Birgit; Gau, Christine; Hans, Wolfgang; Hoelter, Sabine M.; Marschall, Susan; Stoeger, Claudia; Becker, Lore; Fuchs, Helmut; Gailus-Durner, Valerie; Klingenspor, Martin; Klopstock, Thomas; Lengger, Christoph; Stefanie, Leuchtenberger; Wolf, Eckhard; Strom, Tim M.; Wurst, Wolfgang und Hrabě de Angelis, Martin (2016): Viable Ednra (Y129F) mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation. In: Mammalian Genome, Bd. 27, Nr. 11-12: S. 587-598

Klafke, Ruth; Anand, A. Alwin Prem; Wurst, Wolfgang; Prakash, Nilima und Wizenmann, Andrea (2016): Differences in the spatiotemporal expression and epistatic gene regulation of the mesodiencephalic dopaminergic precursor marker PITX3 during chicken and mouse development. In: Development, Bd. 143, Nr. 4: S. 691-702

Wurst, Wolfgang (2016): Animal Models Are Valid to Uncover Disease Mechanisms.
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Bender, Julia; Engeholm, Maik; Ederer, Marion S.; Breu, Johannes; Moller, Thor C.; Michalakis, Stylianos; Rasko, Tamas; Wanker, Erich E.; Biel, Martin; Martinez, Karen L.; Wurst, Wolfgang und Deussing, Jan M. (2015): Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif.
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Truong, Dong-Jiunn Jeffery; Kuehner, Karin; Kuehn, Ralf; Werfel, Stanislas; Engelhardt, Stefan; Wurst, Wolfgang und Ortiz, Oskar (2015): Development of an intein-mediated split-Cas9 system for gene therapy. In: Nucleic Acids Research, Bd. 43, Nr. 13: S. 6450-6458 [PDF, 4MB]

Brandl, Christina; Ortiz, Oskar; Röttig, Bernhard; Wefers, Benedikt; Wurst, Wolfgang und Kühn, Ralf (2015): Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos. In: Febs Open Bio, Bd. 5: S. 26-35

Becker, Lore; Kling, Eva; Schiller, Evelyn; Zeh, Ramona; Schrewe, Anja; Hölter, Sabine M.; Mossbrugger, Ilona; Calzada-Wack, Julia; Strecker, Valentina; Wittig, Ilka; Dumitru, Iulia; Wenz, Tina; Bender, Andreas; Aichler, Michaela; Janik, Dirk; Neff, Frauke; Walch, Axel; Quintanilla-Fend, Leticia; Floss, Thomas; Bekeredjian, Raffi; Gailus-Durner, Valerie; Fuchs, Helmut; Wurst, Wolfgang; Meitinger, Thomas; Prokisch, Holger; Hrabé de Angelis, Martin und Klopstock, Thomas (2014): MTO1-Deficient Mouse Model Mirrors the Human Phenotype Showing Complex I Defect and Cardiomyopathy.
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Gewies, Andreas; Gorka, Oliver; Bergmann, Hanna; Pechloff, Konstanze; Petermann, Franziska; Jeltsch, Katharina M.; Rudelius, Martina; Kriegsmann, Mark; Weichert, Wilko; Horsch, Marion; Beckers, Johannes; Wurst, Wolfgang; Heikenwalder, Mathias; Korn, Thomas; Heissmeyer, Vigo und Ruland, Jürgen (2014): Uncoupling Malt1 Threshold Function from Paracaspase Activity Results in Destructive Autoimmune Inflammation. In: Cell Reports, Bd. 9, Nr. 4: S. 1292-1305 [PDF, 4MB]

Matthes, Michaela; Preusse, Martin; Zhang, Jingzhong; Schechter, Julia; Mayer, Daniela; Lentes, Bernd; Theis, Fabian; Prakash, Nilima; Wurst, Wolfgang und Trümbach, Dietrich (2014): Mouse IDGenes: a reference database for genetic interactions in the developing mouse brain. In: Database-The Journal of Biological Databases and Curation, bau083 [PDF, 1MB]

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Meier, Florian; Giesert, Florian; Delic, Sabit; Faus-Kessler, Theresa; Matheus, Friederike; Simeone, Antonio; Hölter, Sabine M.; Kuehn, Ralf; Weisenhorn, Daniela M. Vogt; Wurst, Wolfgang und Prakash, Nilima (2014): FGF/FGFR2 Signaling Regulates the Generation and Correct Positioning of Bergmann Glia Cells in the Developing Mouse Cerebellum.
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Zumbrennen-Bullough, Kimberly B.; Becker, Lore; Garrett, Lillian; Hölter, Sabine M.; Calzada-Wack, Julia; Mossbrugger, Ilona; Quintanilla-Fend, Leticia; Racz, Ildiko; Rathkolb, Birgit; Klopstock, Thomas; Wurst, Wolfgang; Zimmer, Andreas; Wolf, Eckhard; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabé de Angelis, Martin; Romney, Steven J. und Leibold, Elizabeth A. (2014): Abnormal Brain Iron Metabolism in Irp2 Deficient Mice Is Associated with Mild Neurological and Behavioral Impairments.
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Olszewski, Pawel K.; Rozman, Jan; Jacobsson, Josefin A.; Rathkolb, Birgit; Stromberg, Siv; Hans, Wolfgang; Klockars, Anica; Alsio, Johan; Riserus, Ulf; Becker, Lore; Hoelter, Sabine M.; Elvert, Ralf; Ehrhardt, Nicole; Gailus-Durner, Valerie; Fuchs, Helmut; Fredriksson, Robert; Wolf, Eckhard; Klopstock, Thomas; Wurst, Wolfgang; Levine, Allen S.; Marcus, Claude; Hrabé de Angelis, Martin; Klingenspor, Martin; Schiöth, Helgi B. und Kilimann, Manfred W. (März 2012): Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans.
In: PLOS Genetics 8(3), e1002568. [PDF, 644kB]

Staropoli, John F.; Haliw, Larissa; Biswas, Sunita; Garrett, Lillian; Hölter, Sabine M.; Becker, Lore; Skosyrski, Sergej; Silva-Buttkus, Patricia da; Calzada-Wack, Julia; Neff, Frauke; Rathkolb, Birgit; Rozman, Jan; Schrewe, Anja; Adler, Thure; Puk, Oliver; Sun, Minxuan; Favor, Jack; Racz, Ildikó; Bekeredjian, Raffi; Busch, Dirk H.; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Wolf, Eckhard; Wurst, Wolfgang; Zimmer, Andreas; Lopez, Edith; Harati, Hayat; Hill, Eric; Krause, Daniela S.; Guide, Jolene; Dragileva, Ella; Gale, Evan; Wheeler, Vanessa C.; Boustany, Rose-Mary; Brown, Diane E.; Breton, Sylvie; Ruether, Klaus; Gailus-Durner, Valérie; Fuchs, Helmut; Hrabé de Angelis, Martin und Cotman, Susan L. (2012): Large-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system.
In: PLOS ONE 7(6), e38310 [PDF, 4MB]

Zhang, Jingzhong; Giesert, Florian; Kloos, Karina; Weisenhorn, Daniela M. Vogt; Aigner, Ludwig; Wurst, Wolfgang und Couillard-Despres, Sebastien (2010): A powerful transgenic tool for fate mapping and functional analysis of newly generated neurons. In: BMC Neuroscience 11:158 [PDF, 2MB]

Soeker, Torben; Dalke, Claudia; Puk, Oliver; Floss, Thomas; Becker, Lore; Bolle, Ines; Favor, Jack; Hans, Wolfgang; Hoelter, Sabine M.; Horsch, Marion; Kallnik, Magdalena; Kling, Eva; Moerth, Corinna; Schrewe, Anja; Stigloher, Christian; Topp, Stefanie; Gailus-Durner, Valerie; Naton, Beatrix; Beckers, Johannes; Fuchs, Helmut; Ivandic, Boris; Klopstock, Thomas; Schulz, Holger; Wolf, Eckhard; Wurst, Wolfgang; Bally-Cuif, Laure; de Angelis, Martin Hrabe und Graw, Jochen (2008): Pleiotropic effects in Eya3 knockout mice. In: BMC Developmental Biology 8:118 [PDF, 3MB]

Buchbeitrag

Wefers, Benedikt; Wurst, Wolfgang und Kühn, Ralf (2023): Gene Editing in Mouse Zygotes Using the CRISPR/Cas9 System. In: Saunders, Thomas L. (Hrsg.): Transgenesis. Methods and Protocols. Methods in Molecular Biology, Bd. 2631. New York: Humana Press. S. 207-230

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