Enhancing visual motion discrimination by desynchronizing bifocal oscillatory activity

Salamanca-Giron, Roberto F.; Raffin, Estelle; Zandvliet, Sarah B.; Seeber, Martin; Michel, Christoph M.; Sauseng, Paul; Huxlin, Krystel R. und Hummel, Friedhelm C. (15. Oktober 2021): Enhancing visual motion discrimination by desynchronizing bifocal oscillatory activity. In: NeuroImage, Bd. 240, Nr. 118299: S. 1-12

Abstract

Visual motion discrimination involves reciprocal interactions in the alpha band between the primary visual cortex (V1) and mediotemporal areas (V5/MT). We investigated whether modulating alpha phase synchronization using individualized multisite transcranial alternating current stimulation (tACS) over V5 and V1 regions would improve motion discrimination. We tested 3 groups of healthy subjects with the following conditions: (1) individualized In-Phase V1alpha-V5alpha tACS (0° lag), (2) individualized Anti-Phase V1alpha-V5alpha tACS (180° lag) and (3) sham tACS. Motion discrimination and EEG activity were recorded before, during and after tACS. Performance significantly improved in the Anti-Phase group compared to the In-Phase group 10 and 30Â min after stimulation. This result was explained by decreases in bottom-up alpha-V1 gamma-V5 phase-amplitude coupling. One possible explanation of these results is that Anti-Phase V1alpha-V5alpha tACS might impose an optimal phase lag between stimulation sites due to the inherent speed of wave propagation, hereby supporting optimized neuronal communication.

• Dokumententyp: Zeitschriftenartikel
• Keywords: Visual processing; Motion discrimination; Oscillatory synchronization; Noninvasive brain stimulation; Multisite tACS; Phase-amplitude coupling
• Fakultät: Psychologie und Pädagogik > Department Psychologie > Neuropsychologie und Biologische Psychologie
• Themengebiete: 100 Philosophie und Psychologie > 150 Psychologie
• ISSN: 1053-8119
• Sprache: Englisch