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Anzahl der Publikationen: 81
Zeitschriftenartikel
Giusti, Sebastian A. 
ORCID: https://orcid.org/0000-0002-0257-3027; Pino, Natalia S. ORCID: https://orcid.org/0009-0001-6984-1751; Pannunzio, Camila; Ogando, Mora B. ORCID: https://orcid.org/0000-0002-1453-2628; Armando, Natalia G. ORCID: https://orcid.org/0000-0003-1379-4025; Garrett, Lillian ORCID: https://orcid.org/0000-0003-4880-7076; Zimprich, Annemarie ORCID: https://orcid.org/0000-0003-2078-6779; Becker, Lore ORCID: https://orcid.org/0000-0002-6890-4984; Gimeno, Maria L.; Lukin, Jeronimo ORCID: https://orcid.org/0000-0002-2284-7152; Merino, Florencia L. ORCID: https://orcid.org/0000-0001-7247-2750; Pardi, M. Belen ORCID: https://orcid.org/0000-0003-1942-7533; Pedroncini, Olivia ORCID: https://orcid.org/0009-0009-0613-4126; Di Mauro, Giuliana C. ORCID: https://orcid.org/0000-0001-5685-090X; Durner, Valerie Gailus; Fuchs, Helmut; Hrabe de Angelis, Martin ORCID: https://orcid.org/0000-0002-7898-2353; Patop, Ines L. ORCID: https://orcid.org/0000-0002-2929-0860; Turck, Christoph W. ORCID: https://orcid.org/0000-0002-6585-8636; Deussing, Jan M. ORCID: https://orcid.org/0000-0002-9329-5252; Vogt Weisenhorn, Daniela M. ORCID: https://orcid.org/0000-0002-4566-6506; Jahn, Olaf ORCID: https://orcid.org/0000-0002-3397-8924; Kadener, Sebastian; Hölter, Sabine M. ORCID: https://orcid.org/0000-0003-4878-5241; Brose, Nils ORCID: https://orcid.org/0000-0003-0938-8534; Giesert, Florian ORCID: https://orcid.org/0000-0001-6825-8858; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Marin-Burgin, Antonia ORCID: https://orcid.org/0000-0003-0684-9796 und Refojo, Damian ORCID: https://orcid.org/0000-0002-9798-6413
(2024):
A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuli.
In: Science Advances, Bd. 10, Nr. 21
[PDF, 5MB]
ORCID: https://orcid.org/0000-0002-0257-3027; Pino, Natalia S. ORCID: https://orcid.org/0009-0001-6984-1751; Pannunzio, Camila; Ogando, Mora B. ORCID: https://orcid.org/0000-0002-1453-2628; Armando, Natalia G. ORCID: https://orcid.org/0000-0003-1379-4025; Garrett, Lillian ORCID: https://orcid.org/0000-0003-4880-7076; Zimprich, Annemarie ORCID: https://orcid.org/0000-0003-2078-6779; Becker, Lore ORCID: https://orcid.org/0000-0002-6890-4984; Gimeno, Maria L.; Lukin, Jeronimo ORCID: https://orcid.org/0000-0002-2284-7152; Merino, Florencia L. ORCID: https://orcid.org/0000-0001-7247-2750; Pardi, M. Belen ORCID: https://orcid.org/0000-0003-1942-7533; Pedroncini, Olivia ORCID: https://orcid.org/0009-0009-0613-4126; Di Mauro, Giuliana C. ORCID: https://orcid.org/0000-0001-5685-090X; Durner, Valerie Gailus; Fuchs, Helmut; Hrabe de Angelis, Martin ORCID: https://orcid.org/0000-0002-7898-2353; Patop, Ines L. ORCID: https://orcid.org/0000-0002-2929-0860; Turck, Christoph W. ORCID: https://orcid.org/0000-0002-6585-8636; Deussing, Jan M. ORCID: https://orcid.org/0000-0002-9329-5252; Vogt Weisenhorn, Daniela M. ORCID: https://orcid.org/0000-0002-4566-6506; Jahn, Olaf ORCID: https://orcid.org/0000-0002-3397-8924; Kadener, Sebastian; Hölter, Sabine M. ORCID: https://orcid.org/0000-0003-4878-5241; Brose, Nils ORCID: https://orcid.org/0000-0003-0938-8534; Giesert, Florian ORCID: https://orcid.org/0000-0001-6825-8858; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Marin-Burgin, Antonia ORCID: https://orcid.org/0000-0003-0684-9796 und Refojo, Damian ORCID: https://orcid.org/0000-0002-9798-6413
(2024):
A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuli.
In: Science Advances, Bd. 10, Nr. 21
[PDF, 5MB]
Stroo, Esther; Janssen, Leen; Sin, Olga; Hogewerf, Wytse; Koster, Mirjam; Harkema, Liesbeth; Youssef, Sameh A.; Beschorner, Natalie; Wolters, Anouk H. G.; Bakker, Bjorn; Becker, Lore; Garrett, Lilian; Marschall, Susan; Hoelter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Thathiah, Amanth; Foijer, Floris; Sluis, Bart van de; Deursen, Jan van; Jucker, Matthias; Brun, Alain de und Nollen, Ellen A. A.
(2023):
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain.
In: Life Science Alliance, Bd. 6, Nr. 7, e202201730
[PDF, 2MB]
Garrett, Lillian; Truembach, Dietrich; Spielmann, Nadine; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; De Angelis, Martin Hrabe und Hoelter, Sabine M.
(2022):
A rationale for considering heart/brain axis control in neuropsychiatric disease.
In: Mammalian Genome, Bd. 34, Nr. 2: S. 331-350
[PDF, 7MB]
Kraiger, Markus; Klein-Rodewald, Tanja; Rathkolb, Birgit; Calzada-Wack, Julia; Sanz-Moreno, Adrian; Fuchs, Helmut; Wolf, Eckhard; Gailus-Durner, Valerie und Hrabe de Angelis, Martin
(2022):
Monitoring longitudinal disease progression in a novel murine Kit tumor model using high-field MRI.
In: Scientific Reports, Bd. 12, Nr. 1, 14608
Klein-Rodewald, Tanja; Micklich, Kateryna; Sanz-Moreno, Adrian; Tost, Monica; Calzada-Wack, Julia; Adler, Thure; Klaften, Matthias; Sabrautzki, Sibylle; Aigner, Bernhard; Kraiger, Markus; Gailus-Durner, Valerie; Fuchs, Helmut; Gruender, Albert; Pahl, Heike; Wolf, Eckhard; Hrabe de Angelis, Martin und Rathkolb, Birgit
(2022):
New C3H Kit(N824K/WT) cancer mouse model develops late-onset malignant mammary tumors with high penetrance.
In: Scientific Reports, Bd. 12, Nr. 1, 19793
[PDF, 3MB]
Müller-Eigner, Annika; Sanz-Moreno, Adrian; de-Diego, Irene; Venkatasubramani, Anuroop Venkateswaran; Langhammer, Martina; Gerlini, Raffaele; Rathkolb, Birgit; Aguilar-Pimentel, Antonio; Klein-Rodewald, Tanja; Calzada-Wack, Julia; Becker, Lore; Palma-Vera, Sergio; Gille, Benedikt; Forne, Ignasi; Imhof, Axel; Meng, Chen; Ludwig, Christina; Koch, Franziska; Heiker, John T.; Kuhla, Angela; Caton, Vanessa; Brenmoehl, Julia; Reyer, Henry; Schoen, Jennifer; Fuchs, Helmut; Gailus-Durner, Valerie; Hoeflich, Andreas; Hrabe de Angelis, Martin und Peleg, Shahaf
(2022):
Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse.
In: Communications Biology, Bd. 5, Nr. 1, 408
Png, Grace; Gerlini, Raffaele; Hatzikotoulas, Konstantinos; Barysenka, Andrei; Rayner, N. William; Klaric, Lucija; Rathkolb, Birgit; Aguilar-Pimentel, Juan A.; Rozman, Jan; Fuchs, Helmut; Gailus-Durner, Valerie; Tsafantakis, Emmanouil; Karaleftheri, Maria; Dedoussis, George; Pietrzik, Claus; Wilson, James F.; Hrabe de Angelis, Martin; Becker-Pauly, Christoph; Gilly, Arthur und Zeggini, Eleftheria
(2022):
Identifying causal serum protein-cardiometabolic trait relationships using whole genome sequencing.
In: Human Molecular Genetics, Bd. 32, Nr. 8: S. 1266-1275
Spielmann, Nadine; Schenkl, Christina; Komlodi, Timea; da Silva-Buttkus, Patricia; Heyne, Estelle; Rohde, Jana; Amarie, Oana V.; Rathkolb, Birgit; Gnaiger, Erich; Doenst, Torsten; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin und Szibor, Marten
(2022):
Knockout of the Complex III subunit Uqcrh causes bioenergetic impairment and cardiac contractile dysfunction.
In: Mammalian Genome, Bd. 34, Nr. 2: S. 229-243
Kandaswamy, Surabhi; Zobel, Lena; John, Bina; Santhiya, Sathiyaveedu Thyagarajan; Bogedein, Jacqueline; Przemeck, Gerhard K. H.; Gailus-Durner, Valerie; Fuchs, Helmut; Biel, Martin; Hrabě de Angelis, Martin; Graw, Jochen; Michalakis, Stylianos und Amarie, Oana Veronica
(2022):
Mutations within the cGMP-binding domain of CNGA1 causing autosomal recessive retinitis pigmentosa in human and animal model.
In: Cell Death Discovery, Bd. 8, Nr. 1, 387
Garrett, Lillian; Da Silva-Buttkus, Patricia; Rathkolb, Birgit; Gerlini, Raffaele; Becker, Lore; Sanz-Moreno, Adrian; Seisenberger, Claudia; Zimprich, Annemarie; Aguilar-Pimentel, Antonio; Amarie, Oana V.; Cho, Yi-Li; Kraiger, Markus; Spielmann, Nadine; Calzada-Wack, Julia; Marschall, Susan; Busch, Dirk; Schmitt-Weber, Carsten; Wolf, Eckhard; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hoelter, Sabine M. und de Angelis, Martin Hrabe
(2022):
Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk.
In: Disease Models & Mechanisms, Bd. 15, Nr. 3, dmm049205
[PDF, 2MB]
Xie, Kan; Fuchs, Helmut; Scifo, Enzo; Liu, Dan; Aziz, Ahmad; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; da Silva-Buttkus, Patricia; Calzada-Wack, Julia; Cho, Yi-Li; Deng, Yushuang; Edwards, A. Cole; Garrett, Lillian; Georgopoulou, Christina; Gerlini, Raffaele; Hoelter, Sabine M.; Klein-Rodewald, Tanja; Kramer, Michael; Leuchtenberger, Stefanie; Lountzi, Dimitra; Mayer-Kuckuk, Phillip; Nover, Lena L.; Oestereicher, Manuela A.; Overkott, Clemens; Pearson, Brandon L.; Rathkolb, Birgit; Rozman, Jan; Russ, Jenny; Schaaf, Kristina; Spielmann, Nadine; Sanz-Moreno, Adrian; Stoeger, Claudia; Treise, Irina; Bano, Daniele; Busch, Dirk H.; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Mock, Beverly A.; Salomoni, Paolo; Schmidt-Weber, Carsten; Weiergraber, Marco; Wolf, Eckhard; Wurst, Wolfgang; Gailus-Durner, Valerie; Breteler, Monique M. B.; Hrabe de Angelis, Martin und Ehninger, Dan
(2022):
Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.
In: Nature Communications, Bd. 13, Nr. 1, 6830
[PDF, 7MB]
Schweizer, Ulrich; Wirth, Eva K.; Klopstock, Thomas; Hoelter, Sabine M.; Becker, Lore; Moskovitz, Jackob; Grune, Tilman; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Koehrle, Josef und Schomburg, Lutz
(2022):
Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice.
In: Redox Biology, Bd. 57, 102490
[PDF, 9MB]
Maity-Kumar, Gandhari; Staender, Lisa; DeAngelis, Meri; Lee, Sooyeon; Molenaar, Anna; Becker, Lore; Garrett, Lillian; Amerie, Oana; Hoelter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Feuchtinger, Annette; Gailus-Durner, Valerie; Gárcia-Cáceres, Cristina; Othman, Ahmed E.; Brockmann, Caroline; Schoeffling, Vanessa I.; Beiser, Katja; Krude, Heiko; Mroz, Piotr A.; Hofmann, Susanna; Tuckermann, Jan; DiMarchi, Richard D.; de Angelis, Martin Hrabe; Tschoep, Matthias H.; Pfluger, Paul T. und Mueller, Timo D.
(2022):
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.
In: Molecular Metabolism, Bd. 66, 101616
[PDF, 3MB]
Baumann, Peter; Schriever, Sonja C.; Kullmann, Stephanie; Zimprich, Annemarie; Peter, Andreas; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Wurst, Wolfgang; Tschoep, Matthias H.; Heni, Martin; Hoelter, Sabine M. und Pfluger, Paul T.
(2021):
Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans.
In: Brain and Behavior, Bd. 11, Nr. 1, e01928
[PDF, 705kB]
Vidali, Silvia; Gerlini, Raffaele; Thompson, Kyle; Urquhart, Jill E.; Meisterknecht, Jana; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Breen, Catherine; Calzada-Wack, Julia; Chhabra, Nirav F.; Cho, Yi-Li; Silva-Buttkus, Patricia da; Feichtinger, Rene G.; Gampe, Kristine; Garrett, Lillian; Hoefig, Kai P.; Hoelter, Sabine M.; Jameson, Elisabeth; Klein-Rodewald, Tanja; Leuchtenberger, Stefanie; Marschall, Susan; Mayer-Kuckuk, Philipp; Miller, Gregor; Oestereicher, Manuela A.; Pfannes, Kristina; Rathkolb, Birgit; Rozman, Jan; Sanders, Charlotte; Spielmann, Nadine; Stoeger, Claudia; Szibor, Marten; Treise, Irina; Walter, John H.; Wurst, Wolfgang; Mayr, Johannes A.; Fuchs, Helmut; Gaertner, Ulrich; Wittig, Ilka; Taylor, Robert W.; Newman, William G.; Prokisch, Holger; Gailus-Durner, Valerie und Hrabe de Angelis, Martin
(2021):
Characterising a homozygous two-exon deletion in UQCRH: comparing human and mouse phenotypes.
In: EMBO Molecular Medicine, Bd. 13, Nr. 12, e14397
Biagosch, Caroline A.; Vidali, Silvia; Faerberboeck, Michael; Hensler, Svenja-Viola; Becker, Lore; Amarie, Oana V.; Aguilar-Pimentel, Antonio; Garrett, Lillian; Klein-Rodewald, Tanja; Rathkolb, Birgit; Zanuttigh, Enrica; Calzada-Wack, Julia; Silva-Buttkus, Patricia da; Rozman, Jan; Treise, Irina; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Janik, Dirk; Wurst, Wolfgang; Mayr, Johannes A.; Klopstock, Thomas; Meitinger, Thomas; Prokisch, Holger und Iuso, Arcangela
(2021):
A comprehensive phenotypic characterization of a whole-body Wdr45 knock-out mouse.
In: Mammalian Genome, Bd. 32, Nr. 5: S. 332-349
[PDF, 3MB]
Auffenberg, Eva; Hedrich, Ulrike B. S.; Barbieri, Raffaella; Miely, Daniela; Groschup, Bernhard; Wuttke, Thomas V.; Vogel, Niklas; Luehrs, Philipp; Zanardi, Ilaria; Bertelli, Sara; Spielmann, Nadine; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Pusch, Michael; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Lerche, Holger; Gavazzo, Paola; Plesnila, Nikolaus und Freilinger, Tobias
(2021):
Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model.
In: Journal of Clinical Investigation, Bd. 131, Nr. 21, e142202
[PDF, 3MB]
ORCID: https://orcid.org/0000-0002-0654-387X; Lerche, Holger; Gavazzo, Paola; Plesnila, Nikolaus und Freilinger, Tobias
(2021):
Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model.
In: Journal of Clinical Investigation, Bd. 131, Nr. 21, e142202
[PDF, 3MB]
Garrett, Lillian; Chang, Yoon Jeung; Niedermeier, Kristina M.; Heermann, Tamara; Enard, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Huttner, Wieland B.; Wurst, Wolfgang und Hoelter, Sabine M.
(2020):
A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons.
In: Translational Psychiatry, Bd. 10, Nr. 1, 66
[PDF, 1MB]
Blechner, Christine; Becker, Lore; Fuchs, Helmut; Rathkolb, Birgit; Prehn, Cornelia; Adler, Thure; Calzada-Wack, Julia; Garrett, Lillian; Gailus-Durner, Valerie; Morellini, Fabio; Conrad, Susanne; Hoelter, Sabine M.; Wolf, Eckhard; Klopstock, Thomas; Adamski, Jerzy; Busch, Dirk; de Angelis, Martin Hrabe; Schmeisser, Michael J. und Windhorst, Sabine
(2020):
Physiological relevance of the neuronal isoform of inositol-1,4,5-trisphosphate 3-kinases in mice.
In: Neuroscience Letters, Bd. 735, 135206
Kollmus, Heike; Fuchs, Helmut; Lengger, Christoph; Haselimashhadi, Hamed; Bogue, Molly A.; Ostereicher, Manuela A.; Horsch, Marion; Adler, Thure; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; Beckers, Johannes; Calzada-Wack, Julia; Garrett, Lillian; Hans, Wolfgang; Hoelter, Sabine M.; Klein-Rodewald, Tanja; Maier, Holger; Mayer-Kuckuk, Philipp; Miller, Gregor; Moreth, Kristin; Neff, Frauke; Rathkolb, Birgit; Racz, Ildiko; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Busch, Dirk; Graw, Jochen; Klopstock, Thomas; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Onder; Mason, Jeremy; Torres, Arturo; Balling, Rudi; Mehaan, Terry; Gailus-Durner, Valerie; Schughart, Klaus und de Angelis, Martin Hrabe
(2020):
A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.
In: Mammalian Genome, Bd. 31: S. 30-48
[PDF, 3MB]
Swan, Anna L.; Schuett, Christine; Rozman, Jan; Moreno, Maria del Mar Muniz; Brandmaier, Stefan; Simon, Michelle; Leuchtenberger, Stefanie; Griffiths, Mark; Brommage, Robert; Keskivali-Bond, Piia; Grallert, Harald; Werner, Thomas; Teperino, Raffaele; Becker, Lore; Miller, Gregor; Moshiri, Ala; Seavitt, John R.; Cissell, Derek D.; Meehan, Terrence F.; Acar, Elif F.; Lelliott, Christopher J.; Flenniken, Ann M.; Champy, Marie-France; Sorg, Tania; Ayadi, Abdel; Braun, Robert E.; Cater, Heather; Dickinson, Mary E.; Flicek, Paul; Gallegos, Juan; Ghirardello, Elena J.; Heaney, Jason D.; Jacquot, Sylvie; Lally, Connor; Logan, John G.; Teboul, Lydia; Mason, Jeremy; Spielmann, Nadine; McKerlie, Colin; Murray, Stephen A.; Nutter, Lauryl M. J.; Odfalk, Kristian F.; Parkinson, Helen; Prochazka, Jan; Reynolds, Corey L.; Selloum, Mohammed; Spoutil, Frantisek; Svenson, Karen L.; Vales, Taylor S.; Wells, Sara E.; White, Jacqueline K.; Sedlacek, Radislav; Wurst, Wolfgang; Lloyd, Kent K. C.; Croucher, Peter; Fuchs, Helmut; Williams, Graham R.; Bassett, Duncan; Gailus-Durner, Valerie; Herault, Yann; Mallon, Ann-Marie; Brown, Steve D. M.; Mayer-Kuckuk, Philipp und de Angelis, Martin Hrabe
(2020):
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.
In: PLOS Genetics 16(12), e1009190 [PDF, 2MB]
In: PLOS Genetics 16(12), e1009190 [PDF, 2MB]
Ferreira dos Santos, Maria C.; Anderson, Cole P.; Neschen, Susanne; Zumbrennen-Bullough, Kimberly B.; Romney, Steven J.; Kahle-Stephan, Melanie; Rathkolb, Birgit; Gailus-Durner, Valerie; Fuchs, Helmut; Wolf, Eckhard; Rozman, Jan; Hrabe de Angelis, Martin; Cai, Weiling Maggie; Rajan, Malini; Hu, Jennifer; Dedon, Peter C. und Leibold, Elizabeth A.
(2020):
Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification.
In: Nature Communications, Bd. 11, Nr. 1, 296
[PDF, 3MB]
Sluka, Susanna H. M.; Staempfli, Simon F.; Akhmedov, Alexander; Rodewald, Tanja Klein; Sanz-Moreno, Adrian; Horsch, Marion; Grest, Paula; Rothmeier, Andrea S.; Rathkolb, Birgit; Schrewe, Anja; Beckers, Johannes; Neff, Frauke; Wolf, Eckhard; Camici, Giovanni G.; Fuchs, Helmut; Durner, Valerie Gailus; Hrabe de Angelis, Martin; Luescher, Thomas F.; Ruf, Wolfram und Tanner, Felix C.
(2020):
Murine tissue actor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality.
In: Haematologica, Bd. 105, Nr. 10: S. 2484-2495
Ignatova, Valentina V.; Stolz, Paul; Kaiser, Steffen; Gustafsson, Tobias H.; Lastres, Palma Rico; Sanz-Moreno, Adrian; Cho, Yi-Li; Amarie, Oana V.; Aguilar-Pimentel, Antonio; Klein-Rodewald, Tanja; Calzada-Wack, Julia; Becker, Lore; Marschall, Susan; Kraiger, Markus; Garrett, Lillian; Seisenberger, Claudia; Hoelter, Sabine M.; Borland, Kayla; Logt, Erik van de; Jansen, Pascal W. T. C.; Baltissen, Marijke P.; Valenta, Magdalena; Vermeulen, Michiel; Wurst, Wolfgang; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Rando, Oliver J.; Kellner, Stefanie M.; Bultmann, Sebastian und Schneider, Robert
(2020):
The rRNA m(6)A methyltransferase METTL5 is involved in pluripotency and developmental programs.
In: Genes & Development, Bd. 34: S. 715-729
[PDF, 4MB]
Ignatova, Valentina V.; Kaiser, Steffen; Ho, Jessica Sook Yuin; Bing, Xinyang; Stolz, Paul; Tan, Ying Xim; Lee, Chee Leng; Gay, Florence Pik Hoon; Lastres, Palma Rico; Gerlini, Raffaele; Rathkolb, Birgit; Aguilar-Pimentel, Antonio; Sanz-Moreno, Adrian; Klein-Rodewald, Tanja; Calzada-Wack, Julia; Ibragimov, Emil; Valenta, Magdalena; Lukauskas, Saulius; Pavesi, Andrea; Marschall, Susan; Leuchtenberger, Stefanie; Fuchs, Helmut; Gailus-Durner, Valerie; De Angelis, Martin Hrabe; Bultmann, Sebastian; Rando, Oliver J.; Guccione, Ernesto; Kellner, Stefanie M. und Schneider, Robert
(2020):
METTL6 is a tRNA m(3)C methyltransferase that regulates pluripotency and tumor cell growth.
In: Science Advances, Bd. 6, Nr. 35, eaaz4551
Lucienne, Marie; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Silva-Buttkus, Patricia da; Garrett, Lillian; Holter, Sabine M.; Mayer-Kuckuk, Philipp; Rathkolb, Birgit; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Busch, Dirk H.; Klopstock, Thomas; Schmidt-Weber, Carsten; Wolf, Eckhard; Wurst, Wolfgang; Forny, Merima; Mathis, Deborah; Fingerhut, Ralph; Froese, D. Sean; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin und Baumgartner, Matthias R.
(2020):
In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria.
In: Biochimica et Biophysica Acta-Molecular Basis of Disease, Bd. 1866, Nr. 3, 165622
[PDF, 2MB]
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(2020):
Human and mouse essentiality screens as a resource for disease gene discovery.
In: Nature Communications, Bd. 11, Nr. 1, 655
[PDF, 1MB]
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(2019):
CRN2 binds to TIMP4 and MMP14 and promotes perivascular invasion of glioblastoma cells.
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(2019):
Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.
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(2019):
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.
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[PDF, 7MB]
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(2019):
Claudin-12 is not required for blood-brain barrier tight junction function.
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(2019):
A mouse model for intellectual disability caused by mutations in the X-linked 2 '-O-methyltransferase Ftsj1 gene.
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(2019):
Dusp8 affects hippocampal size and behavior in mice and humans.
In: Scientific Reports, Bd. 9, 19483
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(2018):
Analysis of locomotor behavior in the German Mouse Clinic.
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(2018):
The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?
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Xie, Kan; Ryan, Devon P.; Pearson, Brandon L.; Henzel, Kristin S.; Neff, Frauke; Vidal, Ramon O.; Hennion, Magali; Lehmann, Isabelle; Schleif, Melvin; Schröder, Susanne; Adler, Thure; Rathkolb, Birgit; Rozman, Jan; Schütz, Anna-Lena; Prehn, Cornelia; Mickael, Michel E.; Weiergraber, Marco; Adamski, Jerzy; Busch, Dirk H.; Ehninger, Gerhard; Matynia, Anna; Jackson, Walker S.; Wolf, Eckhard; Fuchs, Helmut; Gailus-Durner, Valerie; Bonn, Stefan; Hrabe de Angelis, Martin und Ehninger, Dan
(2018):
Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 115, Nr. 10, E2348-E2357
[PDF, 2MB]
Treise, Irina; Huber, Eva M.; Klein-Rodewald, Tanja; Heinemeyer, Wolfgang; Grassmann, Simon A.; Basler, Michael; Adler, Thure; Rathkolb, Birgit; Helming, Laura; Andres, Christian; Klaften, Matthias; Landbrecht, Christina; Wieland, Thomas; Strom, Tim M.; McCoy, Kathy D.; Macpherson, Andrew J.; Wolf, Eckhard; Gröttrup, Marcus; Ollert, Markus; Neff, Frauke; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Groll, Michael und Busch, Dirk H.
(2018):
Defective immuno- and thymoproteasome assembly causes severe immunodeficiency.
In: Scientific Reports, Bd. 8, 5975
[PDF, 5MB]
Rozman, Jan; Rathkolb, Birgit; Oestereicher, Manuela A.; Schütt, Christine; Ravindranath, Aakash Chavan; Leuchtenberger, Stefanie; Sharma, Sapna; Kistler, Martin; Willershaeuser, Monja; Brommage, Robert; Meehan, Terrence F.; Mason, Jeremy; Haselimashhadi, Hamed; Hough, Tertius; Mallon, Ann-Marie; Wells, Sara; Santos, Luis; Lelliott, Christopher J.; White, Jacqueline K.; Sorg, Tania; Champy, Marie-France; Bower, Lynette R.; Reynolds, Corey L.; Flenniken, Ann M.; Murray, Stephen A.; Nutter, Lauryl M. J.; Svenson, Karen L.; West, David; Tocchini-Valentini, Glauco P.; Beaudet, Arthur L.; Bosch, Fatima; Braun, Robert B.; Dobbie, Michael S.; Gao, Xiang; Herault, Yann; Moshiri, Ala; Moore, Bret A.; Lloyd, K. C. Kent; McKerlie, Colin; Masuya, Hiroshi; Tanaka, Nobuhiko; Flicek, Paul; Parkinson, Helen E.; Sedlacek, Radislav; Seong, Je Kyung; Wang, Chi-Kuang Leo; Moore, Mark; Brown, Steve D.; Tschoep, Matthias H.; Wurst, Wolfgang; Klingenspor, Martin; Wolf, Eckhard; Beckers, Johannes; Machicao, Fausto; Peter, Andreas; Staiger, Harald; Häring, Hans-Ulrich; Grallert, Harald; Campillos, Monica; Maier, Holger; Fuchs, Helmut; Gailus-Durner, Valerie; Werner, Thomas und Hrabe de Angelis, Martin
(2018):
Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
In: Nature Communications, Bd. 9, 288
[PDF, 2MB]
Nikolakopoulou, Polyxeni; Chatzigeorgiou, Antonios; Kourtzelis, Ioannis; Toutouna, Louiza; Masjkur, Jimmy; Arps-Forker, Carina; Poser, Steven W.; Rozman, Jan; Rathkolb, Birgit; Aguilar-Pimentel, Juan Antonio; Wolf, Eckhard; Klingenspor, Martin; Ollert, Markus; Schmidt-Weber, Carsten; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Tsata, Vasiliki; Monasor, Laura Sebastian; Troullinaki, Maria; Witt, Anke; Anastasiou, Vivian; Chrousos, George; Yi, Chun-Xia; Garcia-Caceres, Cristina; Tschoep, Matthias H.; Bornstein, Stefan R. und Androutsellis-Theotokis, Andreas
(2018):
Streptozotocin-induced beta-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain.
In: Scientific Reports, Bd. 8, 11335
[PDF, 4MB]
Franko, Andras; Camargo, Diana C. Rodriguez; Böddrich, Annett; Garg, Divita; Camargo, Andres Rodriguez; Rathkolb, Birgit; Janik, Dirk; Aichler, Michaela; Feuchtinger, Annette; Neff, Frauke; Fuchs, Helmut; Wanker, Erich E.; Reif, Bernd; Häring, Hans-Ulrich; Peter, Andreas und Hrabe de Angelis, Martin
(2018):
Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice.
In: Scientific Reports, Bd. 8, 1116
[PDF, 6MB]
Fuchs, Helmut; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Cho, Yi-Li; Garrett, Lillian; Hölter, Sabine M.; Irmler, Martin; Kistler, Martin; Kraiger, Markus; Mayer-Kuckuk, Philipp; Moreth, Kristin; Rathkolb, Birgit; Rozman, Jan; Silva Buttkus, Patricia da; Treise, Irina; Zimprich, Annemarie; Gampe, Kristine; Hutterer, Christine; Stoeger, Claudia; Leuchtenberger, Stefanie; Maier, Holger; Miller, Manuel; Scheideler, Angelika; Wu, Moya; Beckers, Johannes; Bekeredjian, Raffi; Brielmeier, Markus; Busch, Dirk H.; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Schmidt-Weber, Carsten; Stoeger, Tobias; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Oender; Zimmer, Andreas; Gailus-Durner, Valerie und Hrabe de Angelis, Martin
(2018):
Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.
In: Behavioural Brain Research, Bd. 352: S. 187-196
Andre, Viola; Gaut, Christine; Scheideler, Angelika; Aguilar-Pimentel, Juan A.; Amarie, Oana V.; Becker, Lore; Garrett, Lillian; Hans, Wolfgang; Hölter, Sabine M.; Janik, Dirk; Moreth, Kristin; Neff, Frauke; Östereicher, Manuela; Racz, Ildiko; Rathkolb, Birgit; Rozman, Jan; Bekeredjian, Raffi; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Schmidt-Weber, Carsten; Wolf, Eckhard; Wurst, Wolfgang; Gailus-Durner, Valerie; Brielmeier, Markus; Fuchs, Helmut und Hrabe de Angelis, Martin
(2018):
Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.
In: PLOS Biology 16(4), e2005019 [PDF, 5MB]
In: PLOS Biology 16(4), e2005019 [PDF, 5MB]
Garrett, Lillian; Becker, Lore; Rozman, Jan; Puk, Oliver; Stoeger, Tobias; Yildirim, Ali Onder; Bohla, Alexander; Eickelberg, Oliver; Hans, Wolfgang; Prehn, Cornelia; Adamski, Jerzy; Klopstock, Thomas; Racz, Ildiko; Zimmer, Andreas; Klingenspor, Martin; Fuchs, Helmut; Gailus-Durner, Valerie; Wurst, Wolfgang; Hrabe de Angelis, Martin; Graw, Jochen und Hölter, Sabine M.
(2018):
Fgf9(Y162C) Mutation Alters Information Processing and Social Memory in Mice.
In: Molecular Neurobiology, Bd. 55, Nr. 6: S. 4580-4595
Heermann, Tamara; Garrett, Lillian; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Graw, Jochen und Holter, Sabine M.
(2018):
Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice.
In: Molecular Neurobiology: S. 1-16
Kumar, Sudhir; Rathkolb, Birgit; Sabrautzki, Sibylle; Krebs, Stefan; Kemter, Elisabeth; Becker, Lore; Beckers, Johannes; Bekeredjian, Raffi; Brommage, Robert; Calzada-Wack, Julia; Garrett, Lillian; Hölter, Sabine M.; Horsch, Marion; Klingenspor, Martin; Klopstock, Thomas; Moreth, Kristin; Neff, Frauke; Rozman, Jan; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Wolf, Eckhard und Aigner, Bernhard
(2017):
Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1(I27N) mutant mice.
In: Journal of Biomedical Science
24:57
[PDF, 870kB]
Schludi, Martin H.; Becker, Lore; Garrett, Lillian; Gendron, Tania F.; Zhou, Qihui; Schreiber, Franziska; Popper, Bastian; Dimou, Leda; Strom, Tim M.; Winkelmann, Juliane; Thaden, Anne von; Rentzsch, Kristin; May, Stephanie; Michaelsen, Meike; Schwenk, Benjamin M.; Tan, Jing; Schoser, Benedikt; Dieterich, Marianne; Petrucelli, Leonard; Hölter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Klopstock, Thomas; Arzberger, Thomas und Edbauer, Dieter
(2017):
Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss.
In: Acta Neuropathologica, Bd. 134, Nr. 2: S. 241-254
Deng, Tao; Postnikov, Yuri; Zhang, Shaofei; Garrett, Lillian; Becker, Lore; Racz, Ildiko; Hoelter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin und Bustin, Michael
(2017):
Interplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation.
In: Nucleic Acids Research, Bd. 45, Nr. 6: S. 3031-3045
Egana, Isabel; Kaito, Hiroshi; Nitzsche, Anja; Becker, Lore; Ballester-Lopez, Carolina; Niaudet, Colin; Petkova, Milena; Liu, Wei; Vanlandewijck, Michael; Vernaleken, Alexandra; Klopstock, Thomas; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Rask-Andersen, Helge; Johansson, Henrik J.; Lehtio, Janne; He, Liqun; Yildirim, Ali O. und Hellstrom, Mats
(2017):
Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.
In: Scientific Reports, Bd. 7, 15453
[PDF, 3MB]
Zimprich, Annemarie; Mroz, Gabi; Meyer zu Reckendorf, Christopher; Anastasiadou, Sofia; Förstner, Philip; Garrett, Lillian; Hölter, Sabine M.; Becker, Lore; Rozman, Jan; Prehn, Cornelia; Rathkolb, Birgit; Moreth, Kristin; Wurst, Wolfgang; Klopstock, Thomas; Klingenspor, Martin; Adamski, Jerzy; Wolf, Eckhard; Bekeredjian, Raffi; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin und Knöll, Bernd
(2017):
Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms.
In: Molecular Neurobiology, Bd. 54, Nr. 10: S. 8242-8262
Salminen, Aaro V.; Garrett, Lillian; Schormair, Barbara; Rozman, Jan; Giesert, Florian; Niedermeier, Kristina M.; Becker, Lore; Rathkolb, Birgit; Racz, Ildiko; Klingenspor, Martin; Klopstock, Thomas; Wolf, Eckhard; Zimmer, Andreas; Gailus-Durner, Valerie; Torres, Miguel; Fuchs, Helmut; Hrabe de Angelis, Martin; Wurst, Wolfgang; Hölter, Sabine M. und Winkelmann, Juliane
(2017):
Meis1: effects on motor phenotypes and the sensorimotor system in mice.
In: Disease Models & Mechanisms, Bd. 10, Nr. 8: S. 981-991
Frey, Helena; Moreth, Kristin; Hsieh, Louise Tzung-Harn; Zeng-Brouwers, Jinyang; Rathkolb, Birgit; Fuchs, Helmut; Gailus-Durner, Valerie; Iozzo, Renato V.; Hrabe de Angelis, Martin und Schäfer, Liliana
(2017):
A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia.
In: Glycoconjugate Journal, Bd. 34, Nr. 3: S. 393-404
Kaklamanos, Aimilios; Rozman, Jan; Roulis, Manolis; Karagianni, Niki; Armaka, Maria; Wu, Moya; Brachthäuser, Laura; Calzada-Wack, Julia; Horsch, Marion; Beckers, Johannes; Rathkolb, Birgit; Adler, Thure; Neff, Frauke; Wolf, Eckhard; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin und Kollias, George
(2017):
Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression.
In: Scientific Reports, Bd. 7, 2397
[PDF, 6MB]
Franko, Andras; Neschen, Susanne; Rozman, Jan; Rathkolb, Birgit; Aichler, Michaela; Feuchtinger, Annette; Brachthäuser, Laura; Neff, Frauke; Kovarova, Marketa; Wolf, Eckhard; Fuchs, Helmut; Häring, Hans-Ulrich; Peter, Andreas und Hrabě de Angelis, Martin
(2017):
Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice.
In: Molecular Metabolism, Bd. 6, Nr. 3: S. 256-266
Fuchs, Helmut; Sabrautzki, Sibylle; Przemeck, Gerhard K. H.; Leuchtenberger, Stefanie; Lorenz-Depiereux, Bettina; Becker, Lore; Rathkolb, Birgit; Horsch, Marion; Garrett, Lillian; Östereicher, Manuela A.; Hans, Wolfgang; Abe, Koichiro; Sagawa, Nobuho; Rozman, Jan; Vargas-Panesso, Ingrid L.; Sandholzer, Michael; Lisse, Thomas S.; Adler, Thure; Aguilar-Pimentel, Juan Antonio; Calzada-Wack, Julia; Ehrhard, Nicole; Elvert, Ralf; Gau, Christine; Hölter, Sabine M.; Micklich, Katja; Moreth, Kristin; Prehn, Cornelia; Puk, Oliver; Racz, Ildiko; Stoeger, Claudia; Vernaleken, Alexandra; Michel, Dian; Diener, Susanne; Wieland, Thomas; Adamski, Jerzy; Bekeredjian, Raffi; Busch, Dirk H.; Favor, John; Graw, Jochen; Klingenspor, Martin; Lengger, Christoph; Maier, Holger; Neff, Frauke; Ollert, Markus; Stoeger, Tobias; Yildirim, Ali Önder; Strom, Tim M.; Zimmer, Andreas; Wolf, Eckhard; Wurst, Wolfgang; Klopstock, Thomas; Beckers, Johannes; Gailus-Durner, Valerie und Hrabé de Angelis, Martin
(2016):
The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.
In: G3-Genes Genomes Genetics, Bd. 6, Nr. 12: S. 4035-4046
Wittmann, Anke; Grimm, Marcus O. W.; Scherthan, Harry; Horsch, Marion; Beckers, Johannes; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Ford, Steven J.; Burton, Neal C.; Razansky, Daniel; Trümbach, Dietrich; Aichler, Michaela; Walch, Axel Karl; Calzada-Wack, Julia; Neff, Frauke; Wurst, Wolfgang; Hartmann, Tobias und Floss, Thomas
(2016):
Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice.
In: PLOS ONE 11(10), e0164298 [PDF, 5MB]
In: PLOS ONE 11(10), e0164298 [PDF, 5MB]
Kumar, Sudhir; Rathkolb, Birgit; Kemter, Elisabeth; Sabrautzki, Sibylle; Michel, Dian; Adler, Thure; Becker, Lore; Beckers, Johannes; Busch, Dirk H.; Garrett, Lillian; Hans, Wolfgang; Hölter, Sabine M.; Horsch, Marion; Klingenspor, Martin; Klopstock, Thomas; Rácz, Ildikó; Rozman, Jan; Panesso, Ingrid Liliana Vargas; Vernaleken, Alexandra; Zimmer, Andreas; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Wolf, Eckhard und Aigner, Bernhard
(2016):
Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3(L423P) Mutant Mice.
In: PLOS ONE 11(3), e0150472 [PDF, 1MB]
In: PLOS ONE 11(3), e0150472 [PDF, 1MB]
Finan, Brian; Clemmensen, Christoffer; Zhu, Zhimeng; Stemmer, Kerstin; Gauthier, Karine; Müller, Luisa; De Angelis, Meri; Moreth, Kristin; Neff, Frauke; Perez-Tilve, Diego; Fischer, Katrin; Lutter, Dominik; Sánchez-Garrido, Miguel A.; Liu, Peng; Tuckermann, Jan; Malehmir, Mohsen; Healy, Marc E.; Weber, Achim; Heikenwalder, Mathias; Jastroch, Martin; Kleinert, Maximilian; Jall, Sigrid; Brandt, Sara; Flamant, Frédéric; Schramm, Karl-Werner; Biebermann, Heike; Doering, Yvonne; Weber, Christian; Habegger, Kirk M.; Keuper, Michaela; Gelfanov, Vasily; Liu, Fa; Köhrle, Josef; Rozman, Jan; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Hofmann, Susanna M.; Yang, Bin; Tschöp, Matthias H.; DiMarchi, Richard und Müller, Timo D.
(2016):
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.
In: Cell, Bd. 167, Nr. 3: S. 843-857
Sabrautzki, Sibylle; Sandholzer, Michael A.; Lorenz-Depiereux, Bettina; Brommage, Robert; Przemeck, Gerhard; Panesso, Ingrid L. Vargas; Vernaleken, Alexandra; Garrett, Lillian; Baron, Katharina; Yildirim, Ali O.; Rozman, Jan; Rathkolb, Birgit; Gau, Christine; Hans, Wolfgang; Hoelter, Sabine M.; Marschall, Susan; Stoeger, Claudia; Becker, Lore; Fuchs, Helmut; Gailus-Durner, Valerie; Klingenspor, Martin; Klopstock, Thomas; Lengger, Christoph; Stefanie, Leuchtenberger; Wolf, Eckhard; Strom, Tim M.; Wurst, Wolfgang und Hrabě de Angelis, Martin
(2016):
Viable Ednra (Y129F) mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation.
In: Mammalian Genome, Bd. 27, Nr. 11-12: S. 587-598
Franko, Andras; Huypens, Peter; Neschen, Susanne; Irmler, Martin; Rozman, Jan; Rathkolb, Birgit; Neff, Frauke; Prehn, Cornelia; Dubois, Guillaume; Baumann, Martina; Massinger, Rebecca; Gradinger, Daniel; Przemeck, Gerhard K. H.; Repp, Birgit; Aichler, Michaela; Feuchtinger, Annette; Schommers, Philipp; Stöhr, Oliver; Sanchez-Lasheras, Carmen; Adamski, Jerzy; Peter, Andreas; Prokisch, Holger; Beckers, Johannes; Walch, Axel K.; Fuchs, Helmut; Wolf, Eckhard; Schubert, Markus; Wiesner, Rudolf J. und de Angelis, Martin Hrabe
(2016):
Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice.
In: Diabetes, Bd. 65, Nr. 9: S. 2540-2552
Schlosser, Anders; Pilecki, Bartosz; Hemstra, Line E.; Kejling, Karin; Kristmannsdottir, Gudlaug B.; Wulf-Johansson, Helle; Moeller, Jesper B.; Füchtbauer, Ernst-Martin; Nielsen, Ole; Kirketerp-Møller, Katrine; Dubey, Lalit K.; Hansen, Pernille B. L.; Stubbe, Jane; Wrede, Christoph; Hegermann, Jan; Ochs, Matthias; Rathkolb, Birgit; Schrewe, Anja; Bekeredjian, Raffi; Wolf, Eckhard; Gailus-Durner, Valérie; Fuchs, Helmut; Hrabě de Angelis, Martin; Lindholt, Jes S.; Holmskov, Uffe und Sorensen, Grith L.
(2016):
MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 36, Nr. 1: S. 122-133
Diener, Susanne; Bayer, Sieglinde; Sabrautzki, Sibylle; Wieland, Thomas; Mentrup, Birgit; Przemeck, Gerhard K. H.; Rathkolb, Birgit; Graf, Elisabeth; Hans, Wolfgang; Fuchs, Helmut; Horsch, Marion; Schwarzmayr, Thomas; Wolf, Eckhard; Klopocki, Eva; Jakob, Franz; Strom, Tim M.; Hrabě de Angelis, Martin und Lorenz-Depiereux, Bettina
(2016):
Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia.
In: Mammalian Genome, Bd. 27, Nr. 3-4: S. 111-121
Korner, Germaine; Scherer, Tanja; Adamsen, Dea; Rebuffat, Alexander; Crabtree, Mark; Rassi, Anahita; Scavelli, Rossana; Homma, Daigo; Ledermann, Birgit; Konrad, Daniel; Ichinose, Hiroshi; Wolfrum, Christian; Horsch, Marion; Rathkolb, Birgit; Klingenspor, Martin; Beckers, Johannes; Wolf, Eckhard; Gailus-Durner, Valérie; Fuchs, Helmut; Hrabě de Angelis, Martin; Blau, Nenad; Rozman, Jan und Thöny, Beat
(2016):
Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice.
In: Journal of inherited Metabolic Disease, Bd. 39, Nr. 2: S. 309-319
Otto, Gordon P.; Rathkolb, Birgit; Oestereicher, Manuela A.; Lengger, Christoph J.; Moerth, Corinna; Micklich, Kateryna; Fuchs, Helmut; Gailus-Durner, Valerie; Wolf, Eckhard und Hrabe de Angelis, Martin
(2016):
Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ Mice (Mus musculus).
In: Journal of the American Association for Laboratory Animal Science, Bd. 55, Nr. 4: S. 375-386
Eisenberg, Tobias; Abdellatif, Mahmoud; Schroeder, Sabrina; Primessnig, Uwe; Stekovic, Slaven; Pendl, Tobias; Harger, Alexandra; Schipke, Julia; Zimmermann, Andreas; Schmidt, Albrecht; Tong, Mingming; Ruckenstuhl, Christoph; Dammbrueck, Christopher; Gross, Angelina S.; Herbst, Viktoria; Magnes, Christoph; Trausinger, Gert; Narath, Sophie; Meinitzer, Andreas; Hu, Zehan; Kirsch, Alexander; Eller, Kathrin; Carmona-Gutierrez, Didac; Büttner, Sabrina; Pietrocola, Federico; Knittelfelder, Oskar; Schrepfer, Emilie; Rockenfeller, Patrick; Simonini, Corinna; Rahn, Alexandros; Horsch, Marion; Moreth, Kristin; Beckers, Johannes; Fuchs, Helmut; Gailus-Durner, Valerie; Neff, Frauke; Janik, Dirk; Rathkolb, Birgit; Rozman, Jan; Hrabe de Angelis, Martin; Moustafa, Tarek; Haemmerle, Guenter; Mayr, Manuel; Willeit, Peter; Frieling-Salewsky, Marion von; Pieske, Burkert; Scorrano, Luca; Pieber, Thomas; Pechlaner, Raimund; Willeit, Johann; Sigrist, Stephan J.; Linke, Wolfgang A.; Mühlfeld, Christian; Sadoshima, Junichi; Dengjel, Joern; Kiechl, Stefan; Kroemer, Guido; Sedej, Simon und Madeo, Frank
(2016):
Cardioprotection and lifespan extension by the natural polyamine spermidine.
In: Nature Medicine, Bd. 22, Nr. 12: S. 1428-1438
Brina, Daniela; Miluzio, Annarita; Ricciardi, Sara; Clarke, Kim; Davidsen, Peter K.; Viero, Gabriella; Tebaldi, Toma; Offenhaeuser, Nina; Rozman, Jan; Rathkolb, Birgit; Neschen, Susanne; Klingenspor, Martin; Wolf, Eckhard; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin Hrabe; Quattrone, Alessandro; Falciani, Francesco und Biffo, Stefano
(2015):
eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription.
In: Nature Communications, Bd. 6, 8261
[PDF, 2MB]
Keller, Johannes; Catala-Lehnen, Philip; Huebner, Antje K.; Jeschke, Anke; Heckt, Timo; Lueth, Anja; Krause, Matthias; Koehne, Till; Albers, Joachim; Schulze, Jochen; Schilling, Sarah; Haberland, Michael; Denninger, Hannah; Neven, Mona; Hermans-Borgmeyer, Irm; Streichert, Thomas; Breer, Stefan; Barvencik, Florian; Levkau, Bodo; Rathkolb, Birgit; Wolf, Eckhard; Calzada-Wack, Julia; Neff, Frauke; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabě de Angelis, Martin; Klutmann, Susanne; Tsourdi, Elena; Hofbauer, Lorenz C.; Kleuser, Burkhard; Chun, Jerold; Schinke, Thorsten und Amling, Michael
(2014):
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts.
In: Nature Communications, Bd. 5, 5215
[PDF, 1MB]
Becker, Lore; Kling, Eva; Schiller, Evelyn; Zeh, Ramona; Schrewe, Anja; Hölter, Sabine M.; Mossbrugger, Ilona; Calzada-Wack, Julia; Strecker, Valentina; Wittig, Ilka; Dumitru, Iulia; Wenz, Tina; Bender, Andreas; Aichler, Michaela; Janik, Dirk; Neff, Frauke; Walch, Axel; Quintanilla-Fend, Leticia; Floss, Thomas; Bekeredjian, Raffi; Gailus-Durner, Valerie; Fuchs, Helmut; Wurst, Wolfgang; Meitinger, Thomas; Prokisch, Holger; Hrabé de Angelis, Martin und Klopstock, Thomas
(2014):
MTO1-Deficient Mouse Model Mirrors the Human Phenotype Showing Complex I Defect and Cardiomyopathy.
In: PLOS ONE 9(12), e114918 [PDF, 1MB]
In: PLOS ONE 9(12), e114918 [PDF, 1MB]
Horsch, Marion; Beckers, Johannes; Fuchs, Helmut; Gailus-Durner, Valérie; Hrabě de Angelis, Martin; Rathkolb, Birgit; Wolf, Eckhard; Aigner, Bernhard und Kemter, Elisabeth
(2014):
Uromodulin Retention in Thick Ascending Limb of Henle's Loop Affects SCD1 in Neighboring Proximal Tubule: Renal Transcriptome Studies in Mouse Models of Uromodulin-Associated Kidney Disease.
In: PLOS ONE 9(11), e113125 [PDF, 911kB]
In: PLOS ONE 9(11), e113125 [PDF, 911kB]
Kraus, Petra; Sivakamasundari, V; Yu, Hong Bing; Xing, Xing; Lim, Siew Lan; Adler, Thure; Pimentel, Juan Antonio Aguilar; Becker, Lore; Bohla, Alexander; Garrett, Lillian; Hans, Wolfgang; Hölter, Sabine M.; Janas, Eva; Moreth, Kristin; Prehn, Cornelia; Puk, Oliver; Rathkolb, Birgit; Rozman, Jan; Adamski, Jerzy; Bekeredjian, Raffi; Busch, Dirk H.; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Neff, Frauke; Ollert, Markus; Stoeger, Tobias; Yildrim, Ali Önder; Eickelberg, Oliver; Wolf, Eckhard; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabě de Angelis, Martin; Lufkin, Thomas und Stanton, Lawrence W.
(2014):
Pleiotropic Functions for Transcription Factor Zscan10.
In: PLOS ONE 9(8), e104568 [PDF, 3MB]
In: PLOS ONE 9(8), e104568 [PDF, 3MB]
Kemter, Elisabeth; Rathkolb, Birgit; Becker, Lore; Bolle, Ines; Busch, Dirk H.; Dalke, Claudia; Elvert, Ralf; Favor, Jack; Graw, Jochen; Hans, Wolfgang; Ivandic, Boris; Kalaydjiev, Svetoslav; Klopstock, Thomas; Rácz, Ildikó; Rozman, Jan; Schrewe, Anja; Schulz, Holger; Zimmer, Andreas; Fuchs, Helmut; Gailus-Durner, Valérie; Hrabé de Angelis, Martin; Wolf, Eckhard und Aigner, Bernhard
(2014):
Standardized, systemic phenotypic analysis of Slc12a(1299F) mutant mice.
In: Journal of Biomedical Science
21:68
[PDF, 493kB]
Zumbrennen-Bullough, Kimberly B.; Becker, Lore; Garrett, Lillian; Hölter, Sabine M.; Calzada-Wack, Julia; Mossbrugger, Ilona; Quintanilla-Fend, Leticia; Racz, Ildiko; Rathkolb, Birgit; Klopstock, Thomas; Wurst, Wolfgang; Zimmer, Andreas; Wolf, Eckhard; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabé de Angelis, Martin; Romney, Steven J. und Leibold, Elizabeth A.
(2014):
Abnormal Brain Iron Metabolism in Irp2 Deficient Mice Is Associated with Mild Neurological and Behavioral Impairments.
In: PLOS ONE 9(6), e98072 [PDF, 5MB]
In: PLOS ONE 9(6), e98072 [PDF, 5MB]
Kemter, Elisabeth; Prueckl, Petra; Sklenak, Stefanie; Rathkolb, Birgit; Habermann, Felix A.; Hans, Wolfgang; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Wolf, Eckhard; Aigner, Bernhard und Wanke, Rüdiger
(2013):
Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice.
In: Human molecular genetics, Bd. 22, Nr. 20: S. 4148-4163
[PDF, 1MB]
Venit, Tomáš; Dzijak, Rastislav; Kalendová, Alžběta; Kahle, Michal; Rohožková, Jana; Schmidt, Volker; Rülicke, Thomas; Rathkolb, Birgit; Hans, Wolfgang; Bohla, Alexander; Eickelberg, Oliver; Stoeger, Tobias; Wolf, Eckhard; Yildirim, Ali Önder; Gailus-Durner, Valérie; Fuchs, Helmut; Hrabé de Angelis, Martin und Hozák, Pavel
(2013):
Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus.
In: PLOS ONE 8(4), e61406 [PDF, 876kB]
In: PLOS ONE 8(4), e61406 [PDF, 876kB]
Pozzi, Benedetta; Amodio, Stefania; Lucano, Caterina; Sciullo, Anna; Ronzoni, Simona; Castelletti, Daniela; Adler, Thure; Treise, Irina; Betsholtz, Ingrid Holmberg; Rathkolb, Birgit; Busch, Dirk H.; Wolf, Eckhard; Fuchs, Helmut; Gailus-Durner, Valérie; Hrabé de Angelis, Martin; Betsholtz, Christer; Casola, Stefano; Di Fiore, Pier Paolo und Offenhäuser, Nina
(2013):
Correction: The Endocytic Adaptor Eps15 Controls Marginal Zone B Cell Numbers.
In: PLOS ONE 8(5) [PDF, 2MB]
In: PLOS ONE 8(5) [PDF, 2MB]
Olszewski, Pawel K.; Rozman, Jan; Jacobsson, Josefin A.; Rathkolb, Birgit; Stromberg, Siv; Hans, Wolfgang; Klockars, Anica; Alsio, Johan; Riserus, Ulf; Becker, Lore; Hoelter, Sabine M.; Elvert, Ralf; Ehrhardt, Nicole; Gailus-Durner, Valerie; Fuchs, Helmut; Fredriksson, Robert; Wolf, Eckhard; Klopstock, Thomas; Wurst, Wolfgang; Levine, Allen S.; Marcus, Claude; Hrabé de Angelis, Martin; Klingenspor, Martin; Schiöth, Helgi B. und Kilimann, Manfred W.
(März 2012):
Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans.
In: PLOS Genetics 8(3), e1002568. [PDF, 644kB]
In: PLOS Genetics 8(3), e1002568. [PDF, 644kB]
Staropoli, John F.; Haliw, Larissa; Biswas, Sunita; Garrett, Lillian; Hölter, Sabine M.; Becker, Lore; Skosyrski, Sergej; Silva-Buttkus, Patricia da; Calzada-Wack, Julia; Neff, Frauke; Rathkolb, Birgit; Rozman, Jan; Schrewe, Anja; Adler, Thure; Puk, Oliver; Sun, Minxuan; Favor, Jack; Racz, Ildikó; Bekeredjian, Raffi; Busch, Dirk H.; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Wolf, Eckhard; Wurst, Wolfgang; Zimmer, Andreas; Lopez, Edith; Harati, Hayat; Hill, Eric; Krause, Daniela S.; Guide, Jolene; Dragileva, Ella; Gale, Evan; Wheeler, Vanessa C.; Boustany, Rose-Mary; Brown, Diane E.; Breton, Sylvie; Ruether, Klaus; Gailus-Durner, Valérie; Fuchs, Helmut; Hrabé de Angelis, Martin und Cotman, Susan L.
(2012):
Large-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system.
In: PLOS ONE 7(6), e38310 [PDF, 4MB]
In: PLOS ONE 7(6), e38310 [PDF, 4MB]
Kleinschnitz, Christoph; Grund, Henrike; Wingler, Kirstin; Armitage, Melanie E.; Jones, Emma; Mittal, Manish; Barit, David; Schwarz, Tobias; Geis, Christian; Kraft, Peter; Barthel, Konstanze; Schuhmann, Michael K.; Herrmann, Alexander M.; Meuth, Sven G.; Stoll, Guido; Meurer, Sabine; Schrewe, Anja; Becker, Lore; Gailus-Durner, Valérie; Fuchs, Helmut; Klopstock, Thomas; Hrabé de Angelis, Martin; Jandeleit-Dahm, Karin; Shah, Ajay M.; Weissmann, Norbert und Schmidt, Harald H. H. W.
(2010):
Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.
In: PLOS Biology 8(9), e1000479 [PDF, 3MB]
In: PLOS Biology 8(9), e1000479 [PDF, 3MB]
Tocchetti, Arianna; Soppo, Charlotte Blanche Ekalle; Zani, Fabio; Bianchi, Fabrizio; Gagliani, Maria Cristina; Pozzi, Benedetta; Rozman, Jan; Elvert, Ralf; Ehrhardt, Nicole; Rathkolb, Birgit; Moerth, Corinna; Horsch, Marion; Fuchs, Helmut; Gailus-Durner, Valérie; Beckers, Johannes; Klingenspor, Martin; Wolf, Eckhard; Hrabé de Angelis, Martin; Scanziani, Eugenio; Tacchetti, Carlo; Scita, Giorgio; Di Fiore, Pier Paolo und Offenhäuser, Nina
(2010):
Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice.
In: PLOS ONE 5(3), e9468 [PDF, 2MB]
In: PLOS ONE 5(3), e9468 [PDF, 2MB]
Noyes, Harry A.; Alimohammadian, Mohammad H.; Agaba, Morris; Brass, Andy; Fuchs, Helmut; Gailus-Durner, Valerie; Hulme, Helen; Iraqi, Fuad; Kemp, Stephen; Rathkolb, Birgit; Wolf, Eckhard; Hrabé de Angelis, Martin; Roshandel, Delnaz und Naessens, Jan
(2009):
Mechanisms controlling anaemia in Trypanosoma congolense infected mice.
In: PLOS ONE 4(4), e5170 [PDF, 1MB]
In: PLOS ONE 4(4), e5170 [PDF, 1MB]
Lisse, Thomas S.; Thiele, Frank; Fuchs, Helmut; Hans, Wolfgang; Przemeck, Gerhard K. H.; Abe, Koichiro; Rathkolb, Birgit; Quintanilla-Martinez, Leticia; Hoelzlwimmer, Gabriele; Helfrich, Miep; Wolf, Eckhard; Ralston, Stuart H. und Hrabé de Angelis, Martin
(Februar 2008):
ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta.
In: PLOS Genetics 4(2) , S. 1-11 [PDF, 941kB]
In: PLOS Genetics 4(2) , S. 1-11 [PDF, 941kB]
Soeker, Torben; Dalke, Claudia; Puk, Oliver; Floss, Thomas; Becker, Lore; Bolle, Ines; Favor, Jack; Hans, Wolfgang; Hoelter, Sabine M.; Horsch, Marion; Kallnik, Magdalena; Kling, Eva; Moerth, Corinna; Schrewe, Anja; Stigloher, Christian; Topp, Stefanie; Gailus-Durner, Valerie; Naton, Beatrix; Beckers, Johannes; Fuchs, Helmut; Ivandic, Boris; Klopstock, Thomas; Schulz, Holger; Wolf, Eckhard; Wurst, Wolfgang; Bally-Cuif, Laure; de Angelis, Martin Hrabe und Graw, Jochen
(2008):
Pleiotropic effects in Eya3 knockout mice.
In: BMC Developmental Biology
8:118
[PDF, 3MB]