Anzahl der Publikationen: 183
Zeitschriftenartikel
Fischer, Luca ORCID: https://orcid.org/0000-0003-2444-416X; Jiang, Linmiao ORCID: https://orcid.org/0000-0002-9009-4236; Dürig, Jan ORCID: https://orcid.org/0000-0002-7672-3905; Schmidt, Christian; Stilgenbauer, Stephan ORCID: https://orcid.org/0000-0002-6830-9296; Bouabdallah, Krimo; Solal-Celigny, Philippe; Scholz, Christian W.; Feugier, Pierre; Wit, Maike de; Trappe, Ralf Ulrich; Hallek, Michael; Graeven, Ullrich ORCID: https://orcid.org/0000-0001-6082-7710; Hänel, Mathias; Hoffmann, Martin; Delwail, Vincent; Macro, Margaret; Greiner, Jochen ORCID: https://orcid.org/0000-0003-1256-173X; Giagounidis, Aristoteles A. N.; Dargel, Beate; Durot, Eric ORCID: https://orcid.org/0000-0003-3463-0089; Foussard, Charles; Silkenstedt, Elisabeth; Weigert, Oliver ORCID: https://orcid.org/0000-0002-0987-7373; Pott, Christiane ORCID: https://orcid.org/0009-0005-9260-8340; Klapper, Wolfram; Hiddemann, Wolfgang; Unterhalt, Michael; Hoster, Eva ORCID: https://orcid.org/0000-0002-0749-1389; Ribrag, Vincent und Dreyling, Martin
(2024):
The addition of bortezomib to rituximab, high-dose cytarabine and dexamethasone in relapsed or refractory mantle cell lymphoma—a randomized, open-label phase III trial of the European mantle cell lymphoma network.
In: Leukemia, Bd. 38: S. 1307-1314
[PDF, 1MB]
Scheubeck, Gabriel ORCID: https://orcid.org/0009-0004-2546-6154; Hoffmann, Martin; Jurinovic, Vindi; Fischer, Luca ORCID: https://orcid.org/0000-0003-2444-416X; Unterhalt, Michael; Schmidt, Christian; Böck, Hans-Peter; Dührsen, Ulrich; Kaesberger, Joachim; Kremers, Stephan; Lindemann, Hans-Walter; Mantovani, Luisa; Hiddemann, Wolfgang; Hoster, Eva ORCID: https://orcid.org/0000-0002-0749-1389 und Dreyling, Martin ORCID: https://orcid.org/0000-0002-0358-5249
(2024):
Rituximab, gemcitabine and oxaliplatin in relapsed or refractory indolent and mantle cell lymphoma: results of a multicenter phase I/II-study of the German Low Grade Lymphoma Study Group.
In: Annals of Hematology, Bd. 103: S. 2373-2380
[PDF, 1MB]
Pastore, Friederike ORCID: https://orcid.org/0000-0002-2220-2346; Gittinger, Hanna; Raab, Susanne; Tschuri, Sebastian; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Rothenberg‐Thurley, Maja; Horny, Hans‐Peter; Werner, Martin; Sauerland, Maria C. ORCID: https://orcid.org/0000-0002-8748-8218; Amler, Susanne ORCID: https://orcid.org/0000-0001-6903-2906; Görlich, Dennis ORCID: https://orcid.org/0000-0002-2574-9419; Berdel, Wolfgang E. ORCID: https://orcid.org/0000-0002-3030-6567; Wörmann, Bernhard ORCID: https://orcid.org/0000-0003-2273-5502; Braess, Jan; Hiddemann, Wolfgang; Tischer, Johanna ORCID: https://orcid.org/0000-0003-1821-1976; Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Metzeler, Klaus H. ORCID: https://orcid.org/0000-0003-3920-7490 und Spiekermann, Karsten ORCID: https://orcid.org/0000-0002-5139-4957
(2023):
Acute megakaryoblastic leukaemia shows high frequency of chromosome 1q aberrations and dismal outcome.
In: British Journal of Haematology, Bd. 202, Nr. 6: S. 1165-1177
[PDF, 1MB]
Batcha, Aarif M. N. ORCID: https://orcid.org/0000-0002-7972-7506; Buckup, Nele; Bamopoulos, Stefanos A ORCID: https://orcid.org/0000-0002-5997-7735; Jurinovic, Vindi; Rothenberg-Thurley, Maja; Gittinger, Hanna; Ksienzyk, Bianka; Dufour, Annika; Schneider, Stephanie; Kontro, Mika; Saad, Joseph ORCID: https://orcid.org/0000-0001-7701-0328; Heckman, Caroline A. ORCID: https://orcid.org/0000-0002-4324-8706; Sauerland, Cristina M.; Görlich, Dennis ORCID: https://orcid.org/0000-0002-2574-9419; Berdel, Wolfgang E. ORCID: https://orcid.org/0000-0002-3030-6567; Wörmann, Bernhard; Krug, Utz; Braess, Jan; Mansmann, Ulrich Robert ORCID: https://orcid.org/0000-0002-9955-8906; Hiddemann, Wolfgang; Spiekermann, Karsten ORCID: https://orcid.org/0000-0002-5139-4957; Metzeler, Klaus H. ORCID: https://orcid.org/0000-0003-3920-7490 und Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432
(2023):
Germline SNPs previously implicated as prognostic biomarkers do not associate with outcomes in intensively treated AML.
In: Blood Advances, Bd. 7, Nr. 6: S. 1040-1044
Niederwieser, Dietger ORCID: https://orcid.org/0000-0002-4737-1103; Lang, Thomas; Krahl, Rainer; Heinicke, Thomas; Maschmeyer, Georg; Al-Ali, Haifa Kathrin; Schwind, Sebastian; Jentzsch, Madlen; Cross, Michael; Kahl, Christoph; Wolf, Hans-Heinrich; Sayer, Herbert; Schulze, Antje; Dreger, Peter; Hegenbart, Ute; Krämer, Alwin; Junghanss, Christian; Mügge, Lars-Olof; Hähling, Detlev; Hirt, Carsten; Späth, Christian; Peter, Norma; Opitz, Bernhard; Florschütz, Axel; Reifenrath, Kolja; Zojer, Niklas; Scholl, Sebastian; Pönisch, Wolfram; Heyn, Simone; Vucinic, Vladan; Hochhaus, Andreas; Aul, Carlo; Giagounidis, Aristoteles; Balleisen, Leopold; Oldenkott, Bernd; Staib, Peter; Kiehl, Michael; Schütte, Wolfgang; Naumann, Ralph; Eimermacher, Hartmut; Dörken, Bernd; Sauerland, Cristina; Lengfelder, Eva; Hiddemann, Wolfgang; Wörmann, Bernhard; Müller-Tidow, Carsten; Serve, Hubert; Schliemann, Christoph; Hehlmann, Rüdiger; Berdel, Wolfgang E.; Pfirrmann, Markus ORCID: https://orcid.org/0000-0002-8948-0690; Krug, Utz und Hoffmann, Verena S. ORCID: https://orcid.org/0000-0003-1478-5390
(2023):
Different treatment strategies versus a common standard arm (CSA) in patients with newly diagnosed AML over the age of 60 years: a randomized German inter-group study.
In: Annals of Hematology, Bd. 102: S. 547-561
[PDF, 3MB]
Stevens, Wendy B. C.; Los-de Vries, G. Tjitske; Langois-Jacques, Carole; Clear, Andrew J.; Stathi, Phylicia; Sander, Birgitta; Rosenwald, Andreas; Calaminici, Maria; Hoster, Eva ORCID: https://orcid.org/0000-0002-0749-1389; Hiddemann, Wolfgang; Gaulard, Philippe; Salles, Gilles; Klapper, Wolfram; Xerri, Luc; Burton, Catherine; Tooze, Reuben M.; Smith, Alexandra G.; Buske, Christian; Scott, David W.; Natkunam, Yasodha; Advani, Ranjana; Sehn, Laurie H.; Raemaekers, John; Gribben, John; Lockmer, Sandra; Kimby, Eva; Kersten, Marie José; Maucort-Boulch, Delphine; Ylstra, Bauke; Dijk, Erik van und Jong, Daphne de
(2023):
Genetic and Microenvironment Features Do Not Distinguish Follicular Lymphoma Patients Requiring Immediate or Deferred Treatment.
In: HemaSphere, Bd. 7, Nr. 4, e863
Fischer, Luca ORCID: https://orcid.org/0000-0003-2444-416X; Jiang, Linmiao ORCID: https://orcid.org/0000-0002-9009-4236; Bittenbring, Joerg Thomas; Huebel, Kai; Schmidt, Christian; Duell, Johannes; Metzner, Bernd; Krauter, Juergen; Glass, Bertram; Huettmann, Andreas; Schaefer-Eckart, Kerstin; Silkenstedt, Elisabeth; Klapper, Wolfram; Hiddemann, Wolfgang; Unterhalt, Michael; Dreyling, Martin und Hoster, Eva ORCID: https://orcid.org/0000-0002-0749-1389
(2023):
The addition of rituximab to chemotherapy improves overall survival in mantle cell lymphoma—a pooled trials analysis.
In: Annals of Hematology, Bd. 102: S. 2791-2801
[PDF, 1MB]
Pott, Christiane ORCID: https://orcid.org/0009-0005-9260-8340; Jurinovic, Vindi; Trotman, Judith ORCID: https://orcid.org/0000-0001-8009-4593; Kehden, Britta; Unterhalt, Michael; Herold, Michael ORCID: https://orcid.org/0000-0002-6801-3292; Jagt, Richard van der ORCID: https://orcid.org/0000-0001-5706-0109; Janssens, Ann; Kneba, Michael; Mayer, Jiri ORCID: https://orcid.org/0000-0003-0567-9887; Young, Moya; Schmidt, Christian; Knapp, Andrea; Nielsen, Tina; Brown, Helen ORCID: https://orcid.org/0009-0007-3637-891X; Spielewoy, Nathalie; Harbron, Chris; Bottos, Alessia; Mundt, Kirsten; Marcus, Robert; Hiddemann, Wolfgang und Hoster, Eva ORCID: https://orcid.org/0000-0002-0749-1389
(2023):
Minimal Residual Disease Status Predicts Outcome in Patients With Previously Untreated Follicular Lymphoma. A Prospective Analysis of the Phase III GALLIUM Study.
In: Journal of Clinical Oncology
[PDF, 794kB]
Rausch, Christian; Hiddemann, Wolfgang; Bergwelt-Baildon, Michael von; Spiekermann, Karsten und Herold, Tobias
(2022):
Akute Myeloische Leukämien – Update 2022.
In: Deutsche Medizinische Wochenschrift, Bd. 147, Nr. 17: S. 1108-1113
Alcazer, Vincent; Bonaventura, Paola; Tonon, Laurie; Michel, Emilie; Mutez, Virginie; Fabres, Clementine; Chuvin, Nicolas; Boulos, Rasha; Estornes, Yann; Maguer-Satta, Veronique; Geistlich, Kevin; Viari, Alain; Metzeler, Klaus H.; Hiddemann, Wolfgang; Batch, Aarif M. N.; Herold, Tobias; Caux, Christophe und Depil, Stephane
(2022):
HERVs characterize normal and leukemia stem cells and represent a source of shared epitopes for cancer immunotherapy.
In: American Journal of Hematology, Bd. 97, Nr. 9: S. 1200-1214
Casulo, Carla ORCID: https://orcid.org/0000-0003-4998-9932; Dixon, Jesse G.; Le-Rademacher, Jennifer ORCID: https://orcid.org/0000-0002-2234-7430; Hoster, Eva ORCID: https://orcid.org/0000-0002-0749-1389; Hochster, Howard S. ORCID: https://orcid.org/0000-0002-9893-1529; Hiddemann, Wolfgang; Marcus, Robert; Kimby, Eva; Herold, Michael; Sebban, Catherine; Gyan, Emmanuel ORCID: https://orcid.org/0000-0002-7651-9189; Foon, Kenneth; Nielsen, Tina; Vitolo, Umberto ORCID: https://orcid.org/0000-0001-7772-2747; Salles, Gilles A. ORCID: https://orcid.org/0000-0002-9541-8666; Shi, Qian und Flowers, Christopher R.
(2022):
Validation of POD24 as a robust early clinical end point of poor survival in FL from 5225 patients on 13 clinical trials.
In: Blood, Bd. 139, Nr. 11: S. 1684-1693
Papaioannou, Dimitrios; Ozer, Hatice G.; Nicolet, Deedra; Urs, Amog P.; Herold, Tobias; Mrozek, Krzysztof; Batcha, Aarif M. N.; Metzeler, Klaus H.; Yilmaz, Ayse S.; Volinia, Stefano; Bill, Marius; Kohlschmidt, Jessica; Pietrzak, Maciej; Walker, Christopher J.; Carroll, Andrew J.; Bräss, Jan; Powell, Bayard L.; Eisfeld, Ann-Kathrin; Uy, Geoffrey L.; Wang, Eunice S.; Kolitz, Jonathan E.; Stone, Richard M.; Hiddemann, Wolfgang; Byrd, John C.; Bloomfield, Clara D. und Garzon, Ramiro
(2022):
Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia.
In: Haematologica, Bd. 107, Nr. 5: S. 1034-1044
Mentz, Michael; Keay, William ORCID: https://orcid.org/0000-0002-8794-7322; Strobl, Carolin Dorothea ORCID: https://orcid.org/0000-0003-2257-6281; Antoniolli, Martina ORCID: https://orcid.org/0000-0003-2720-9886; Adolph, Louisa; Heide, Michael; Lechner, Axel; Haebe, Sarah; Osterode, Elisa ORCID: https://orcid.org/0000-0003-4359-2096; Kridel, Robert ORCID: https://orcid.org/0000-0003-0287-7124; Ziegenhain, Christoph ORCID: https://orcid.org/0000-0003-2208-4877; Wange, Lucas Esteban ORCID: https://orcid.org/0000-0002-3275-9156; Hildebrand, Johannes Adrian ORCID: https://orcid.org/0000-0002-5451-8038; Shree, Tanaya ORCID: https://orcid.org/0000-0003-0694-3512; Silkenstedt, Elisabeth; Staiger, Annette M. ORCID: https://orcid.org/0000-0002-5896-3200; Ott, German; Horn, Heike; Szczepanowski, Monika; Richter, Julia ORCID: https://orcid.org/0000-0002-9543-4084; Levy, Ronald; Rosenwald, Andreas; Enard, Wolfgang; Zimber-Strobl, Ursula ORCID: https://orcid.org/0000-0002-9765-5251; Bergwelt-Baildon, Michael von; Hiddemann, Wolfgang; Klapper, Wolfram ORCID: https://orcid.org/0000-0001-7208-4117; Schmidt-Supprian, Marc; Rudelius, Martina; Bararia, Deepak; Passerini, Verena und Weigert, Oliver ORCID: https://orcid.org/0000-0002-0987-7373
(2022):
PARP14 is a novel target in STAT6 mutant follicular lymphoma.
In: Leukemia, Bd. 36, Nr. 9: S. 2281-2292
[PDF, 3MB]
Pastore, Friederike ORCID: https://orcid.org/0000-0002-2220-2346; Pastore, Alessandro; Rothenberg-Thurley, Maja; Metzeler, Klaus H.; Ksienzyk, Bianka; Schneider, Stephanie; Bohlander, Stefan K.; Braess, Jan; Sauerland, Maria C.; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard; Bergwelt-Baildon, Michael von; Hiddemann, Wolfgang und Spiekermann, Karsten
(2022):
Molecular profiling of patients with cytogenetically normal acute myeloid leukemia and hyperleukocytosis.
In: Cancer, Bd. 128, Nr. 24: S. 4213-4222
[PDF, 1MB]
Middeke, Jan M.; Metzeler, Klaus H.; Roellig, Christoph; Kraemer, Michael; Eckardt, Jan-Niklas; Stasik, Sebastian; Greif, Philipp A.; Spiekermann, Karsten; Rothenberg-Thurley, Maja; Krug, Utz; Braess, Jan; Kraemer, Alwin; Hochhaus, Andreas; Bruemmendorf, Tim H.; Naumann, Ralph; Steffen, Bjoern; Einsele, Hermann; Schaich, Markus; Burchert, Andreas; Neubauer, Andreas; Goerlich, Dennis; Sauerland, Cristina; Schaefer-Eckart, Kerstin; Schliemann, Christoph; Krause, Stefan W.; Haenel, Mathias; Frickhofen, Norbert; Noppeney, Richard; Kaiser, Ulrich; Kaufmann, Martin; Kunadt, Desiree; Woermann, Bernhard; Sockel, Katja; Bonin, Malte von; Herold, Tobias; Mueller-Tidow, Carsten; Platzbecker, Uwe; Berdel, Wolfgang E.; Serve, Hubert; Baldus, Claudia D.; Ehninger, Gerhard; Schetelig, Johannes; Hiddemann, Wolfgang; Bornhaeuser, Martin; Stoelzel, Friedrich und Thiede, Christian
(2022):
Differential impact of IDH1/2 mutational subclasses on outcome in adult AML: results from a large multicenter study.
In: Blood Advances, Bd. 6, Nr. 5: S. 1394-1405
Stathis, Anastasios; Mey, Ulrich; Schar, Sami; Hitz, Felicitas; Pott, Christiane; Mach, Nicolas; Krasniqi, Fatime; Novak, Urban; Schmidt, Christian; Hohloch, Karin; Kienle, Dirk Lars; Hess, Dagmar; Moccia, Alden A.; Unterhalt, Michael; Eckhardt, Katrin; Hayoz, Stefanie; Forestieri, Gabriela; Rossi, Davide; Dirnhofer, Stefan; Ceriani, Luca; Sartori, Giulio; Bertoni, Francesco; Buske, Christian; Zucca, Emanuele und Hiddemann, Wolfgang
(2022):
SAKK 35/15: a phase 1 trial of obinutuzumab in combination with venetoclax in patients with previously untreated follicular lymphoma.
In: Blood Advances, Bd. 6, Nr. 13: S. 3911-3920
Los-deVries, G. Tjitske; Stevens, Wendy B. C.; Dijk, Erik van; Langois-Jacques, Carole; Clear, Andrew J.; Stathi, Phylicia; Roemer, Margaretha G. M.; Mendeville, Matias; Hijmering, Nathalie J.; Sander, Birgitta; Rosenwald, Andreas; Calaminici, Maria; Hoster, Eva; Hiddemann, Wolfgang; Gaulard, Philippe; Salles, Gilles; Horn, Heike; Klapper, Wolfram; Xerri, Luc; Burton, Catherine; Tooze, Reuben M.; Smith, Alexandra G.; Buske, Christian; Scott, David W.; Natkunam, Yasodha; Advani, Ranjana; Sehn, Laurie H.; Raemaekers, John; Gribben, John; Kimby, Eva; Kersten, Marie Jose; Maucort-Boulch, Delphine; Ylstra, Bauke und Jong, Daphne de
(2022):
Genomic and microenvironmental landscape of stage I follicular lymphoma, compared with stage III/IV.
In: Blood Advances, Bd. 6, Nr. 18: S. 5482-5493
Hermine, Olivier ORCID: https://orcid.org/0000-0003-2574-3874; Jiang, Linmiao ORCID: https://orcid.org/0000-0002-9009-4236; Walewski, Jan ORCID: https://orcid.org/0000-0003-4247-2674; Bosly, André; Thieblemont, Catherine ORCID: https://orcid.org/0000-0002-9941-2448; Szymczyk, Michal; Pott, Christiane; Salles, Gilles ORCID: https://orcid.org/0000-0002-9541-8666; Feugier, Pierre; Hübel, Kai; Haioun, Corinne; Casasnovas, René Olivier ORCID: https://orcid.org/0000-0002-1156-8983; Schmidt, Christian; Bouabdallah, Kamal; Ribrag, Vincent; Kanz, Lothar; Dürig, Jan ORCID: https://orcid.org/0000-0002-7672-3905; Metzner, Bernd; Sibon, David ORCID: https://orcid.org/0000-0002-9205-625X; Cheminant, Morgane; Burroni, Barbara; Klapper, Wolfram; Hiddemann, Wolfgang; Unterhalt, Michael; Hoster, Eva ORCID: https://orcid.org/0000-0002-0749-1389 und Dreyling, Martin ORCID: https://orcid.org/0000-0002-0358-5249
(2022):
High-Dose Cytarabine and Autologous Stem-Cell Transplantation in Mantle Cell Lymphoma. Long-Term Follow-Up of the Randomized Mantle Cell Lymphoma Younger Trial of the European Mantle Cell Lymphoma Network.
In: Journal of Clinical Oncology, Bd. 41, Nr. 3: S. 479-484
Kunadt, Desiree; Stasik, Sebastian; Metzeler, Klaus H.; Roellig, Christoph; Schliemann, Christoph; Greif, Philipp A.; Spiekermann, Karsten; Rothenberg-Thurley, Maja; Krug, Utz; Braess, Jan; Kraemer, Alwin; Hochhaus, Andreas; Scholl, Sebastian; Hilgendorf, Inken; Bruemmendorf, Tim H.; Jost, Edgar; Steffen, Bjoern; Bug, Gesine; Einsele, Hermann; Goerlich, Dennis; Sauerland, Cristina; Schaefer-Eckart, Kerstin; Krause, Stefan W.; Haenel, Mathias; Hanoun, Maher; Kaufmann, Martin; Woermann, Bernhard; Kramer, Michael; Sockel, Katja; Egger-Heidrich, Katharina; Herold, Tobias; Ehninger, Gerhard; Burchert, Andreas; Platzbecker, Uwe; Berdel, Wolfgang E.; Mueller-Tidow, Carsten; Hiddemann, Wolfgang; Serve, Hubert; Stelljes, Matthias; Baldus, Claudia D.; Neubauer, Andreas; Schetelig, Johannes; Thiede, Christian; Bornhaeuser, Martin; Middeke, Jan M. und Stoelzel, Friedrich
(2022):
Impact of IDH1 and IDH2 mutational subgroups in AML patients after allogeneic stem cell transplantation.
In: Journal of Hematology & Oncology, Bd. 15, Nr. 1, 126
Horn, Heike; Jurinovic, Vindi; Leich, Ellen; Kalmbach, Sabrina; Bausinger, Julia; Staiger, Annette M.; Kurz, Katrin S.; Möller, Peter; Bernd, Heinz-Wolfram; Feller, Alfred C.; Koch, Karoline; Klapper, Wolfram; Stein, Harald; Hansmann, Martin-Leo; Hartmann, Sylvia; Scheubeck, Gabriel; Dreyling, Martin ORCID: https://orcid.org/0000-0002-0358-5249; Hiddemann, Wolfgang; Herfarth, Klaus; Engelhard, Marianne; Rosenwald, Andreas; Hoster, Eva ORCID: https://orcid.org/0000-0002-0749-1389 und Ott, German
(2022):
Molecular Cytogenetic Profiling Reveals Similarities and Differences Between Localized Nodal and Systemic Follicular Lymphomas.
In: HemaSphere, Bd. 6, Nr. 9, e767
[PDF, 1MB]
Herold, Michael; Hoster, Eva ORCID: https://orcid.org/0000-0002-0749-1389; Janssens, Ann; McCarthy, Helen; Tedeschi, Alessandra; Pocock, Chris; Rosta, Andras; Trněný, Marek; Nielsen, Tina G.; Knapp, Andrea; Hiddemann, Wolfgang und Marcus, Robert
(2022):
Immunochemotherapy and Maintenance With Obinutuzumab or Rituximab in Patients With Previously Untreated Marginal Zone Lymphoma in the Randomized GALLIUM Trial.
In: HemaSphere, Bd. 6, Nr. 3, e699
[PDF, 558kB]
Papaioannou, Dimitrios; Ozer, Hatice G.; Nicolet, Deedra; Urs, Amog P.; Herold, Tobias; Mrózek, Krzysztof; Batcha, Aarif M. N.; Metzeler, Klaus H.; Yilmaz, Ayse S.; Volinia, Stefano; Bill, Marius; Kohlschmidt, Jessica; Pietrzak, Maciej; Walker, Christopher J.; Carroll, Andrew J.; Braess, Jan; Powell, Bayard L.; Eisfeld, Ann-Kathrin; Uy, Geoffrey L.; Wang, Eunice S.; Kolitz, Jonathan E.; Stone, Richard M.; Hiddemann, Wolfgang; Byrd, John C.; Bloomfield, Clara D. und Garzon, Ramiro
(2021):
Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia.
In: Haematologica
Wang, Yun; Cai, Yan-yu; Herold, Tobias; Nie, Run-cong; Zhang, Yu; Gale, Robert Peter; Metzeler, Klaus H.; Zeng, Yun; Wang, Shun-qing; Pan, Xue-yi; Yang, Tong-hua; Wu, Yuan-bin; Zhang, Qing; Wuxiao, Zhi-jun; Du, Xin; Liang, Zhi-wei; Su, Yong-zhong; Xu, Jing-bo; Wang, Yong-qing; Liu, Ze-lin; Wu, Jian-wei; Zhang, Xiong; Wu, Bing-yi; Xiao, Ruo-zhi; Wang, San-bin; Li, Jin-yuan; Chi, Pei-dong; Zhang, Qian-yi; Chen, Si-liang; Qin, Zhe-yuan; Zhang, Xin-mei; Zhong, Na; Hiddemann, Wolfgang; Liu, Qi-fa; Zhang, Bei und Liang, Yang
(2021):
An Immune Risk Score Predicts Survival of Patients with Acute Myeloid Leukemia Receiving Chemotherapy.
In: Clinical Cancer Research, Bd. 27, Nr. 1: S. 255-266
Strefford, Jonathan C.; Nowicka, Malgorzata; Hargreaves, Chantal E.; Burton, Cathy; Davies, Andrew; Ganderton, Rosalind; Hiddemann, Wolfgang; Iriyama, Chisako; Klapper, Wolfram; Latham, Kate V.; Martelli, Maurizio; Mir, Farheen; Parker, Helen; Potter, Kathleen N.; Rose-Zerilli, Matthew J. J.; Sehn, Laurie H.; Trneny, Marek; Vitolo, Umberto; Bolen, Christopher R.; Klein, Christian; Knapp, Andrea; Oestergaard, Mikkel Z. und Cragg, Mark S.
(2021):
Single-nucleotide Fc gamma receptor polymorphisms do not impact obinutuzumab/rituximab outcome in patients with lymphoma.
In: Blood Advances, Bd. 5, Nr. 15: S. 2935-2944
Moser, Christian; Jurinovic, Vindi; Sagebiel-Kohler, Sabine; Ksienzyk, Bianka; Batcha, Aarif M. N.; Dufour, Annika; Schneider, Stephanie; Rothenberg-Thurley, Maja; Sauerland, Cristina M.; Gorlich, Dennis; Berdel, Wolfgang E.; Krug, Utz; Mansmann, Ulrich; Hiddemann, Wolfgang; Braess, Jan; Spiekermann, Karsten; Greif, Philipp A.; Vosberg, Sebastian; Metzeler, Klaus H.; Kumbrink, Joerg und Herold, Tobias
(2021):
A clinically applicable gene expression-based score predicts resistance to induction treatment in acute myeloid leukemia.
In: Blood Advances, Bd. 5, Nr. 22: S. 4752-4761
Kempf, Julia M.; Weser, Sabrina; Bartoschek, Michael D.; Metzeler, Klaus H.; Vick, Binje; Herold, Tobias; Voelse, Kerstin; Mattes, Raphael; Scholz, Manuela; Wange, Lucas E.; Festini, Moreno; Ugur, Enes; Roas, Maike; Weigert, Oliver; Bultmann, Sebastian; Leonhardt, Heinrich; Schotta, Gunnar; Hiddemann, Wolfgang; Jeremias, Irmela und Spiekermann, Karsten
(2021):
Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML.
In: Scientific Reports, Bd. 11, Nr. 1, 5838
Kayser, Sabine; Schlenk, Richard F.; Lebon, Delphine; Carre, Martin; Goetze, Katharina S.; Stoelzel, Friedrich; Berceanu, Ana; Schaefer-Eckart, Kerstin; Peterlin, Pierre; Hicheri, Yosr; Rahme, Ramy; Raffoux, Emmanuel; Chermat, Fatiha; Krause, Stefan W.; Aulitzky, Walter E.; Rigaudeau, Sophie; Noppeney, Richard; Berthon, Celine; Goerner, Martin; Jost, Edgar; Carassou, Philippe; Keller, Ulrich; Orvain, Corentin; Braun, Thorsten; Saillard, Colombe; Arar, Ali; Kunzmann, Volker; Wemeau, Mathieu; de Wit, Maike; Niemann, Dirk; Bonmati, Caroline; Schwaenen, Carsten; Abraham, Julie; Aljijakli, Ahmad; Haiat, Stephanie; Kraemer, Alwin; Reichle, Albrecht; Gnadler, Martina; Willekens, Christophe; Spiekermann, Karsten; Hiddemann, Wolfgang; Mueller-Tidow, Carsten; Thiede, Christian; Roellig, Christoph; Serve, Hubert; Bornhaeuser, Martin; Baldus, Claudia D.; Lengfelder, Eva; Fenaux, Pierre; Platzbecker, Uwe und Ades, Lionel
(2021):
Characteristics and outcome of patients with low-/intermediate-risk acute promyelocytic leukemia treated with arsenic trioxide: an international collaborative.
In: Haematologica, Bd. 106, Nr. 12: S. 3100-3106
Hirt, Carsten; Hoster, Eva; Unterhalt, Michael; Haenel, Mathias; Prange-Krex, Gabriele; Forstpointner, Roswitha; Florschuetz, Axel; Graeven, Ullrich; Frickhofen, Norbert; Wulf, Gerald; Lengfelder, Eva; Lerchenmueller, Christian; Schlag, Rudolf; Dierlamm, Judith; Fischer von Weikersthal, Ludwig; Ahmed, Asima; Harich, Hanns-Detlev; Rosenwald, Andreas; Klapper, Wolfram; Dreyling, Martin; Hiddemann, Wolfgang und Herold, Michael
(2021):
Rituximab Maintenance Versus Observation After Immunochemotherapy (R-CHOP, R-MCP, and R-FCM) in Untreated Follicular Lymphoma Patients: A Randomized Trial of the Ostdeutsche Studiengruppe Hamatologie und Onkologie and the German Low-Grade Lymphoma Study Group.
In: Hemasphere, Bd. 5, Nr. 7, e600
Casulo, Carla; Dixon, Jesse G.; Ou, Fang-Shu; Hoster, Eva; Peterson, Bruce A.; Hochster, Howard S.; Brice, Pauline; Ladetto, Marco; Hiddemann, Wolfgang; Marcus, Robert; Kimby, Eva; Herold, Michael; Nielsen, Tina; Morschhauser, Franck; Rummel, Mathias; Hagenbeek, Anton; Vitolo, Umberto; Salles, Gilles A.; Shi, Qian und Flowers, Christopher R.
(2021):
Outcomes of older patients with follicular lymphoma using individual data from 5922 patients in 18 randomized controlled trials.
In: Blood Advances, Bd. 5, Nr. 6: S. 1737-1745
Zoellner, Anna-Katharina; Unterhalt, Michael; Stilgenbauer, Stephan; Huebel, Kai; Thieblemont, Catherine; Metzner, Bernd; Topp, Max; Truemper, Lorenz; Schmidt, Christian; Bouabdallah, Kamal; Krauter, Jürgen; Lenz, Georg; Duerig, Jan; Vergote, Vibeke; Schaefer-Eckart, Kerstin; Andre, Marc; Kluin-Nelemans, Hanneke C.; Hoof, Achiel van; Klapper, Wolfram; Hiddemann, Wolfgang; Dreyling, Martin und Hoster, Eva
(2021):
Long-term survival of patients with mantle cell lymphoma after autologous haematopoietic stem-cell transplantation in first remission: a post-hoc analysis of an open-label multicentre, randomised, phase 3 trial.
In: Lancet Haematology, Bd. 8, Nr. 9, E648-E657
Zoellner, Anna-Katharina; Unterhalt, Michael; Stilgenbauer, Stephan; Hübel, Kai; Klapper, Wolfram; Hiddemann, Wolfgang; Dreyling, Martin und Hoster, Eva
(2021):
Long-term survival of patients with mantle cell lymphoma after autologous haematopoietic stem-cell transplantation in first remission: a post-hoc analysis of an open-label, multicentre, randomised, phase 3 trial.
In: The Lancet. Haematology, Bd. 8, Nr. 9, e648-e657
Hirt, Carsten; Hoster, Eva; Unterhalt, Michael; Hänel, Mathias; Prange-Krex, Gabriele; Forstpointner, Roswitha; Florschütz, Axel; Graeven, Ullrich; Frickhofen, Norbert; Wulf, Gerald; Lengfelder, Eva; Lerchenmüller, Christian; Schlag, Rudolf; Dierlamm, Judith; Fischer von Weikersthal, Ludwig; Ahmed, Asima; Harich, Hanns-Detlev; Rosenwald, Andreas; Klapper, Wolfram; Dreyling, Martin; Hiddemann, Wolfgang und Herold, Michael
(2021):
Rituximab Maintenance Versus Observation After Immunochemotherapy (R-CHOP, R-MCP, and R-FCM) in Untreated Follicular Lymphoma Patients. A Randomized Trial of the Ostdeutsche Studiengruppe Hämatologie und Onkologie and the German Low-Grade Lymphoma Study Group.
In: HemaSphere, Bd. 5, Nr. 7, e600
Alig, Stefan; Jurinovic, Vindi; Esfahani, Mohammad Shahrokh; Haebe, Sarah; Passerini, Verena; Hellmuth, Johannes C.; Gaitzsch, Erik; Keay, William; Tahiri, Natyra; Zoellner, Anna-Katharina; Rosenwald, Andreas; Klapper, Wolfram; Stein, Harald; Feller, Alfred C.; Ott, German; Staiger, Annette M.; Horn, Heike; Hansmann, Martin-Leo; Pott, Christiane; Unterhalt, Michael; Schmidt, Christian; Dreyling, Martin; Alizadeh, Ash A.; Hiddemann, Wolfgang; Hoster, Eva und Weigert, Oliver
(22. September 2020):
Evaluating upfront high-dose consolidation after R-CHOP for follicular lymphoma by clinical and genetic risk models.
In: Blood Advances, Bd. 4, Nr. 18: S. 4451-4462
Vaikari, Vijaya Pooja; Du, Yang; Wu, Sharon; Zhang, Tian; Metzeler, Klaus H.; Batcha, Aarif M. N.; Herold, Tobias; Hiddemann, Wolfgang; Akhtari, Mojtaba und Alachkar, Houda
(April 2020):
Clinical and preclinical characterization of CD99 isoforms in acute myeloid leukemia.
In: Haematologica, Bd. 105, Nr. 4
[PDF, 4MB]
Opatz, Sabrina; Bamopoulos, Stefanos A.; Metzeler, Klaus H.; Herold, Tobias; Ksienzyk, Bianka; Braeundl, Kathrin; Tschuri, Sebastian; Vosberg, Sebastian; Konstandin, Nikola P.; Wang, Christine; Hartmann, Luise; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Schneider, Stephanie; Thiede, Christian; Middeke, Jan Moritz; Stoelzel, Friedrich; Roellig, Christoph; Schetelig, Johannes; Ehninger, Gerhard; Kraemer, Alwin; Braess, Jan; Goerlich, Dennis; Sauerland, Maria Cristina; Berdel, Wolfgang E.; Woermann, Bernhard J.; Hiddemann, Wolfgang; Spiekermann, Karsten; Bohlander, Stefan K. und Greif, Philipp A.
(2020):
The clinical mutatome of core binding factor leukemia.
In: Leukemia, Bd. 34, Nr. 6: S. 1553-1562
Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Rothenberg-Thurley, Maja; Grunwald, Victoria V.; Janke, Hanna; Goerlich, Dennis; Sauerland, Maria C.; Konstandin, Nikola P.; Dufour, Annika; Schneider, Stephanie; Neusser, Michaela; Ksienzyk, Bianka; Greif, Philipp A.; Subklewe, Marion; Faldum, Andreas; Bohlander, Stefan K.; Braess, Jan; Wörmann, Bernhard; Krug, Utz; Berdel, Wolfgang E.; Hiddemann, Wolfgang; Spiekermann, Karsten und Metzeler, Klaus H.
(2020):
Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia.
In: Leukemia, Bd. 34: S. 3161-3172
[PDF, 2MB]
Redondo Monte, Enric; Wilding, Anja; Leubolt, Georg; Kerbs, Paul; Bagnoli, Johannes W.; Hartmann, Luise; Hiddemann, Wolfgang; Chen-Wichmann, Linping; Krebs, Stefan; Blum, Helmut; Cusan, Monica; Vick, Binje; Jeremias, Irmela; Enard, Wolfgang; Theurich, Sebastian; Wichmann, Christian und Greif, Philipp A.
(2020):
ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells.
In: Oncogene, Bd. 39: S. 3195-3205
[PDF, 1MB]
Bamopoulos, Stefanos A.; Batcha, Aarif M. N.; Jurinovic, Vindi; Rothenberg-Thurley, Maja; Janke, Hanna; Ksienzyk, Bianka; Philippou-Massier, Julia; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Schneider, Stephanie; Konstandin, Nikola; Sauerland, Maria Cristina; Görlich, Dennis; Berdel, Wolfgang E.; Woermann, Bernhard J.; Bohlander, Stefan K.; Canzar, Stefan; Mansmann, Ulrich; Hiddemann, Wolfgang; Braess, Jan; Spiekermann, Karsten; Metzeler, Klaus H. und Herold, Tobias
(2020):
Clinical presentation and differential splicing of SRSF2, U2AF1 and SF3B1 mutations in patients with acute myeloid leukemia.
In: Leukemia, Bd. 34, Nr. 10: S. 2621-2634
Lichtenegger, Felix S.; Schnorfeil, Frauke M.; Rothe, Maurine; Deiser, Katrin; Altmann, Torben; Bücklein, Veit L.; Köhnke, Thomas; Augsberger, Christian; Konstandin, Nikola P.; Spiekermann, Karsten; Moosmann, Andreas; Boehm, Stephan; Boxberg, Melanie; Heemskerk, Mirjam H. M.; Goerlich, Dennis; Wittmann, Georg; Wagner, Beate; Hiddemann, Wolfgang; Schendel, Dolores J.; Kvalheim, Gunnar; Bigalke, Iris und Subklewe, Marion
(2020):
Toll‐like receptor 7/8‐matured RNA‐transduced dendritic cells as post‐remission therapy in acute myeloid leukaemia: results of a phase I trial.
In: Clinical & Translational Immunology, Bd. 9, Nr. 3, e1117
[PDF, 1MB]
Staiger, Annette M.; Hoster, Eva; Jurinovic, Vindi; Winter, Stefan; Leich, Ellen; Kalla, Claudia; Möller, Peter; Bernd, Heinz-Wolfram; Feller, Alfred C.; Koch, Karoline; Klapper, Wolfram; Stein, Harald; Hansmann, Martin-Leo; Hartmann, Sylvia; Dreyling, Martin; Weigert, Oliver; Hiddemann, Wolfgang; Herfarth, Klaus; Rosenwald, Andreas; Engelhard, Marianne; Ott, German und Horn, Heike
(2020):
Localized- and advanced-stage follicular lymphomas differ in their gene expression profiles.
In: Blood, Bd. 135, Nr. 3: S. 181-190
Mir, Farheen; Mattiello, Federico; Grigg, Andrew; Herold, Michael; Hiddemann, Wolfgang; Marcus, Robert; Seymour, John F.; Bolen, Christopher R.; Knapp, Andrea; Nielsen, Tina und Casulo, Carla
(2020):
Follicular Lymphoma Evaluation Index (FLEX): A new clinical prognostic model that is superior to existing risk scores for predicting progression-free survival and early treatment failure after frontline immunochemotherapy.
In: American Journal of Hematology, Bd. 95, Nr. 12: S. 1503-1510
Bararia, Deepak; Hildebrand, Johannes A.; Stolz, Sebastian; Haebe, Sarah; Alig, Stefan; Trevisani, Christopher P.; Osorio-Barrios, Francisco; Bartoschek, Michael D.; Mentz, Michael; Pastore, Alessandro; Gaitzsch, Erik; Heide, Michael; Jurinovic, Vindi; Rautter, Katharina; Gunawardana, Jay; Sabdia, Muhammed B.; Szczepanowski, Monika; Richter, Julia; Klapper, Wolfram; Louissaint, Abner; Ludwig, Christina; Bultmann, Sebastian; Leonhardt, Heinrich; Eustermann, Sebastian; Hopfner, Karl-Peter; Hiddemann, Wolfgang; Bergwelt-Baildon, Michael von; Steidl, Christian; Kridel, Robert; Tobin, Joshua W. D.; Gandhi, Maher K.; Weinstock, David M.; Schmidt-Supprian, Marc; Sarosi, Menyhart B.; Rudelius, Martina; Passerini, Verena; Mautner, Josef und Weigert, Oliver
(2020):
Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma.
In: Cell Reports, Bd. 31, Nr. 5, 107522
Stief, Sophie M.; Hanneforth, Anna-Li; Weser, Sabrina; Mattes, Raphael; Carlet, Michela; Liu, Wen-Hsin; Bartoschek, Michael D.; Moreno, Helena Dominguez; Oettle, Matthias; Kempf, Julia; Vick, Binje; Ksienzyk, Bianka; Tizazu, Belay; Rothenberg-Thurley, Maja; Quentmeier, Hilmar; Hiddemann, Wolfgang; Vosberg, Sebastian; Greif, Philipp A.; Metzeler, Klaus H.; Schotta, Gunnar; Bultmann, Sebastian; Jeremias, Irmela; Leonhardt, Heinrich und Spiekermann, Karsten
(2020):
Loss of KDM6A confers drug resistance in acute myeloid leukemia.
In: Leukemia, Bd. 34, Nr. 1: S. 50-62
Rutherford, Sarah C.; Herold, Michael; Hiddemann, Wolfgang; Kostakoglu, Lale; Marcus, Robert; Martelli, Maurizio; Sehn, Laurie H.; Trneny, Marek; Trotman, Judith; Vitolo, Umberto; Nielsen, Tina; Mattiello, Federico; Sahin, Deniz; Sellam, Gila und Martin, Peter
(2020):
Impact of bone marrow biopsy on response assessment in immunochemotherapy-treated lymphoma patients in GALLIUM and GOYA.
In: Blood Advances, Bd. 4, Nr. 8: S. 1589-1593
Zinzani, Pier Luigi; Flinn, Ian W.; Yuen, Sam L. S.; Topp, Max S.; Rusconi, Chiara; Fleury, Isabelle; Le Du, Katell; Arthur, Christopher; Pro, Barbara; Gritti, Giuseppe; Crump, Michael; Petrich, Adam; Samineni, Divya; Sinha, Arijit; Punnoose, Elizabeth A.; Szafer-Glusman, Edith; Spielewoy, Nathalie; Mobasher, Mehrdad; Humphrey, Kathryn; Kornacker, Martin und Hiddemann, Wolfgang
(2020):
Venetoclax-rituximab with or without bendamustine vs bendamustine-rituximab in relapsed/refractory follicular lymphoma.
In: Blood, Bd. 136, Nr. 23: S. 2628-2637
Jamois, Candice; Gibiansky, Ekaterina; Gibiansky, Leonid; Buchheit, Vincent; Sahin, Denis; Cartron, Guillaume; Marcus, Robert; Hiddemann, Wolfgang; Seymour, John F.; Strefford, Jonathan C.; Hargreaves, Chantal E.; Meneses-Lorente, Georgina; Frey, Nicolas und Fingerle-Rowson, Guenter
(2019):
Role of obinutuzumab exposure on clinical outcome of follicular lymphoma treated with first-line immunochemotherapy.
In: British Journal of Clinical Pharmacology, Bd. 85, Nr. 7: S. 1495-1506
Grunwald, Victoria V.; Hentrich, Marcus; Schiel, Xaver; Dufour, Annika; Schneider, Stephanie; Neusser, Michaela; Subklewe, Marion; Fiegl, Michael; Hiddemann, Wolfgang; Spiekermann, Karsten; Rothenberg-Thurley, Maja und Metzeler, Klaus H.
(2019):
Patients with spontaneous remission of high-risk MDS and AML show persistent preleukemic clonal hematopoiesis.
In: Blood Advances, Bd. 3, Nr. 18: S. 2696-2699
Angenendt, Linus; Bormann, Eike; Pabst, Caroline; Alla, Vijay; Goerlich, Dennis; Braun, Leonie; Dohlich, Kim; Schwoeppe, Christian; Bohlander, Stefan K.; Arteaga, Maria Francisca; Wethmar, Klaus; Hartmann, Wolfgang; Angenendt, Adrian; Kessler, Torsten; Mesters, Rolf M.; Stelljes, Matthias; Rothenberg-Thurley, Maja; Spiekermann, Karsten; Hebert, Josee; Sauvageau, Guy; Valk, Peter J. M.; Loewenberg, Bob; Serve, Hubert; Müller-Tidow, Carsten; Lenz, Georg; Woermann, Bernhard J.; Sauerland, M. Christina; Hiddemann, Wolfgang; Berdel, Wolfgang E.; Krug, Utz; Metzeler, Klaus H.; Mikesch, Jan-Henrik; Herold, Tobias und Schliemann, Christoph
(2019):
The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia.
In: Leukemia, Bd. 33, Nr. 12: S. 2830-2841
Joos, Stefan; Nettelbeck, Dirk M.; Reil-Held, Anette; Engelmann, Katja; Moosmann, Alexandra; Eggert, Angelika; Hiddemann, Wolfgang; Krause, Mechthild; Peters, Christoph; Schuler, Martin; Schulze-Osthoff, Klaus; Serve, Hubert; Wick, Wolfgang; Puchta, Josef und Baumann, Michael
(2019):
German Cancer Consortium (DKTK) - A national consortium for translational cancer research.
In: Molecular Oncology, Bd. 13, Nr. 3: S. 535-542
Klanova, Magdalena; Oestergaard, Mikkel Z.; Trneny, Marek; Hiddemann, Wolfgang; Marcus, Robert; Sehn, Laurie H.; Vitolo, Umberto; Bazeos, Alexandra; Goede, Valentin; Zeuner, Harald; Knapp, Andrea; Sahin, Deniz; Spielewoy, Nathalie; Bolen, Christopher R.; Cardona, Andres; Klein, Christian; Venstrom, Jeffrey M.; Nielsen, Tina und Fingerle-Rowson, Guenter
(2019):
Prognostic Impact of Natural Killer Cell Count in Follicular Lymphoma and Diffuse Large B-cell Lymphoma Patients Treated with Immunochemotherapy.
In: Clinical Cancer Research, Bd. 25, Nr. 15: S. 4634-4643
Seymour, John F.; Marcus, Robert; Davies, Andrew; Gallop-Evans, Eve; Grigg, Andrew; Haynes, Andrew; Herold, Michael; Illmer, Thomas; Nilsson-Ehle, Herman; Soekler, Martin; Duenzinger, Ulrich; Nielsen, Tina; Launonen, Aino und Hiddemann, Wolfgang
(2019):
Association of early disease progression and very poor survival in the GALLIUM study in follicular lymphoma: benefit of obinutuzumab in reducing the rate of early progression.
In: Haematologica, Bd. 104, Nr. 6: S. 1202-1208
Batcha, Aarif M. N.; Bamopoulos, Stefanos A.; Kerbs, Paul; Kumar, Ashwini; Jurinovic, Vindi; Rothenberg-Thurley, Maja; Ksienzyk, Bianka; Philippou-Massier, Julia; Krebs, Stefan; Blum, Helmut; Schneider, Stephanie; Konstandin, Nikola; Bohlander, Stefan K.; Heckman, Caroline; Kontro, Mika; Hiddemann, Wolfgang; Spiekermann, Karsten; Braess, Jan; Metzeler, Klaus H.; Greif, Philipp A.; Mansmann, Ulrich und Herold, Tobias
(2019):
Allelic Imbalance of Recurrently Mutated Genes in Acute Myeloid Leukaemia.
In: Scientific Reports, Bd. 9, Nr. 11796
[PDF, 1MB]
Alig, Stefan; Jurinovic, Vindi; Pastore, Alessandro; Haebe, Sarah; Schmidt, Christian; Zoellner, Anna-Katharina; Dreyling, Martin; Unterhalt, Michael; Hoster, Eva; Hiddemann, Wolfgang und Weigert, Oliver
(2019):
Impact of age on clinical risk scores in follicular lymphoma.
In: Blood Advances, Bd. 3, Nr. 7: S. 1033-1038
Herold, Tobias; Jurinovic, Vindi; Batcha, Aarif Mohamed Nazeer; Bamopoulos, Stefanos A.; Rothenberg-Thurley, Maja; Ksienzyk, Bianka; Hartmann, Luise; Greif, Philipp A.; Phillippou-Massier, Julia; Krebs, Stefan; Blum, Helmut; Amler, Susanne; Schneider, Stephanie; Konstandin, Nikola P.; Sauerland, Maria Cristina; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Tischer, Johanna; Subklewe, Marion; Bohlander, Stefan K.; Braess, Jan; Hiddemann, Wolfgang; Metzeler, Klaus H.; Mansmann, Ulrich und Spiekermann, Karsten
(März 2018):
A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia.
In: Haematologica, Bd. 103, Nr. 3: S. 456-65
Mottok, Anja; Jurinovic, Vindi; Farinha, Pedro; Rosenwald, Andreas; Leich, Ellen; Ott, German; Horn, Heike; Klapper, Wolfram; Boesl, Michael; Hiddemann, Wolfgang; Steidl, Christian; Connors, Joseph M.; Sehn, Laurie H.; Gascoyne, Randy D.; Hoster, Eva; Weigert, Oliver und Kridel, Robert
(Januar 2018):
FOXP1 expression is a prognostic biomarker in follicular lymphoma treated with rituximab-containing regimens.
In: Blood, Bd. 131, Nr. 2: S. 226-235
Alig, Stefan; Jurinovic, Vindi; Pastore, Alessandro; Bararia, Deepak; Häbe, Sarah; Hellmuth, Johannes C.; Kridel, Robert; Gascoyne, Randy; Schmidt, Christian; Zöllner, Anna; Buske, Christian; Dreyling, Martin; Unterhalt, Michael; Hiddemann, Wolfgang; Hoster, Eva und Weigert, Oliver
(2018):
Impact of age on genetics and treatment efficacy in follicular lymphoma.
In: Haematologica
Greif, Philipp A.; Hartmann, Luise; Vosberg, Sebastian; Stief, Sophie M.; Mattes, Raphael; Hellmann, Ines; Metzeler, Klaus H.; Herold, Tobias; Bamopoulos, Stefanos A.; Kerbs, Paul; Jurinovic, Vindi; Schumacher, Daniela; Pastore, Friederike; Bräundl, Kathrin; Zellmeier, Evelyn; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Neumann, Martin; Baldus, Claudia D.; Bohlander, Stefan K.; Wolf, Stephan; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Hiddemann, Wolfgang und Spiekermann, Karsten
(2018):
Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients.
In: Clinical Cancer Research, Bd. 24, Nr. 7: S. 1716-1726
Issels, Rolf D.; Lindner, Lars H.; Verweij, Jaap; Wessalowski, Rüdiger; Reichardt, Peter; Wust, Peter; Ghadjar, Pirus; Hohenberger, Peter; Angele, Martin K.; Salat, Christoph; Vujaskovic, Zeljko; Daugaard, Soeren; Mella, Olav; Mansmann, Ulrich; Dürr, Hans Roland; Knösel, Thomas; Abdel-Rahman, Sultan; Schmidt, Michael; Hiddemann, Wolfgang; Jauch, Karl-Walter; Belka, Claus und Gronchi, Alessandro
(2018):
Effect of Neoadjuvant Chemotherapy Plus Regional Hyperthermia on Long-term Outcomes Among Patients With Localized High-Risk Soft Tissue Sarcoma: The EORTC 62961-ESHO 95 Randomized Clinical Trial.
In: JAMA Oncology, Bd. 4, Nr. 4: S. 483-492
Jurinovic, Vindi; Metzner, Bernd; Pfreundschuh, Michael; Schmitz, Norbert; Wandt, Hannes; Keller, Ulrich; Dreger, Peter; Dreyling, Martin; Hiddemann, Wolfgang; Unterhalt, Michael; Hoster, Eva und Weigert, Oliver
(2018):
Autologous Stem Cell Transplantation for Patients with Early Progression of Follicular Lymphoma: A Follow-Up Study of 2 Randomized Trials from the German Low Grade Lymphoma Study Group.
In: Biology of Blood and Marrow Transplantation
Hornung, Roman; Jurinovic, Vindi; Batcha, Aarif M. N.; Bamopoulos, Stefanos A.; Rothenberg-Thurley, Maja; Amler, Susanne; Sauerland, Maria Cristina; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Bohlander, Stefan K.; Braess, Jan; Hiddemann, Wolfgang; Lehmann, Sören; Mareschal, Sylvain; Spiekermann, Karsten; Metzeler, Klaus H.; Herold, Tobias und Boulesteix, Anne-Laure
(2018):
Mediation analysis reveals common mechanisms of RUNX1 point mutations and RUNX1/RUNX1T1 fusions influencing survival of patients with acute myeloid leukemia.
In: Scientific Reports, Bd. 8, Nr. 1: S. 1-13
[PDF, 1MB]
Schranz, Katrin; Hubmann, Max; Harin, Egor; Vosberg, Sebastian; Herold, Tobias; Metzeler, Klaus H.; Rothenberg-Thurley, Maja; Janke, Hanna; Bräundl, Kathrin; Ksienzyk, Bianka; Batcha, Aarif M. N.; Schaaf, Sebastian; Schneider, Stephanie; Bohlander, Stefan K.; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Braess, Jan; Krebs, Stefan; Hiddemann, Wolfgang; Mansmann, Ulrich; Spiekermann, Karsten und Greif, Philipp A.
(2018):
Clonal heterogeneity of FLT3-ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia.
In: Oncotarget, Bd. 9, Nr. 53: S. 30128-30145
[PDF, 2MB]
Konstandin, Nikola P.; Pastore, Friederike; Herold, Tobias; Dufour, Annika; Rothenberg-Thurley, Maja; Hinrichsen, Tanja; Ksienzyk, Bianka; Tschuri, Sebastian; Schneider, Stephanie; Hoster, Eva; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Sauerland, Maria C.; Braess, Jan; Bohlander, Stefan K.; Klein, Hanns-Georg; Hiddemann, Wolfgang; Metzeler, Klaus H. und Spiekermann, Karsten
(2018):
Genetic heterogeneity of cytogenetically normal AML with mutations of CEBPA.
In: Blood Advances, Bd. 2, Nr. 20: S. 2724-2731
Michallet, Anne-Sophie; Aktan, Melih; Hiddemann, Wolfgang; Ilhan, Osman; Johansson, Peter; Laribi, Kamel; Meddeb, Balkis; Moreno, Carol; Raposo, Joao; Schuh, Anna; Unal, Ali; Widenius, Tom; Bernhardt, Alf; Kellershohn, Kerstin; Messeri, Dimitri; Osborne, Stuart und Leblond, Veronique
(2018):
Rituximab plus bendamustine or chlorambucil for chronic lymphocytic leukemia: primary analysis of the randomized, open-label MABLE study.
In: Haematologica, Bd. 103, Nr. 4: S. 698-706
[PDF, 614kB]
Trotman, Judith; Barrington, Sally F.; Belada, David; Meignan, Michel; MacEwan, Robert; Owen, Carolyn; Ptacnik, Vaclav; Rosta, Andras; Fingerle-Rowson, Günter R.; Zhu, Jiawen; Nielsen, Tina; Sahin, Deniz; Hiddemann, Wolfgang; Marcus, Robert E. und Davies, Andrew
(2018):
Prognostic value of end-of-induction PET response after first-line immunochemotherapy for follicular lymphoma (GALLIUM): secondary analysis of a randomised, phase 3 trial.
In: Lancet Oncology, Bd. 19, Nr. 11: S. 1530-1542
Bräss, Jan; Amler, Susanne; Kreuzer, Karl-Anton; Spiekermann, Karsten; Lindemann, Hans Walter; Lengfelder, Eva; Graeven, Ullrich; Staib, Peter; Ludwig, Wolf-Dieter; Biersack, Harald; Ko, Yon-Dschun; Uppenkamp, Michael J.; Wit, Maike de; Korsten, Stefan; Peceny, Rudolf; Gaska, Tobias; Schiel, Xaver; Behringer, Dirk M.; Kiehl, Michael G.; Zinngrebe, Bettina; Meckenstock, Gerald; Römer, Eva; Medgenberg, Dirk; Spaeth-Schwalbe, Ernst; Massenkeil, Gero; Hindahl, Heidrun; Schwerdtfeger, Rainer; Trenn, Guido; Sauerland, Cristina; Koch, Raphael; Lablans, Martin; Faldum, Andreas; Görlich, Dennis; Bohlander, Stefan K.; Schneider, Stephanie; Dufour, Annika; Buske, Christian; Fiegl, Michael; Subklewe, Marion; Bräss, Birgit; Unterhalt, Michael; Baumgartner, Anja; Wörmann, Bernhard; Beelen, Dietrich und Hiddemann, Wolfgang
(2018):
Sequential high-dose cytarabine and mitoxantrone (S-HAM) versus standard double induction in acute myeloid leukemia-a phase 3 study.
In: Leukemia, Bd. 32, Nr. 12: S. 2558-2571
Hellmuth, Johannes C.; Louissaint, Abner Jr.; Szczepanowski, Monika; Haebe, Sarah; Pastore, Alessandro; Alig, Stefan; Staiger, Annette M.; Hartmann, Sylvia; Kridel, Robert; Ducar, Matthew D.; Koch, Peter; Dreyling, Martin; Hansmann, Martin-Leo; Ott, German; Rosenwald, Andreas; Gascoyne, Randy D.; Weinstock, David M.; Hiddemann, Wolfgang; Klapper, Wolfram und Weigert, Oliver
(2018):
Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles.
In: Blood, Bd. 132, Nr. 16: S. 1695-1702
Prassek, Victoria V.; Rothenberg-Thurley, Maja; Sauerland, Maria C.; Herold, Tobias; Janke, Hanna; Ksienzyk, Bianka; Konstandin, Nikola P.; Goerlich, Dennis; Krug, Utz; Faldum, Andreas; Berdel, Wolfgang E.; Wörmann, Bernhard; Braess, Jan; Schneider, Stephanie; Subklewe, Marion; Bohlander, Stefan K.; Hiddemann, Wolfgang; Spiekermann, Karsten und Metzeler, Klaus H.
(2018):
Genetics of acute myeloid leukemia in the elderly: mutation spectrum and clinical impact in intensively treated patients aged 75 years or older.
In: Haematologica, Bd. 103, Nr. 11: S. 1853-1861
[PDF, 1MB]
Hiddemann, Wolfgang; Barbui, Anna Maria; Canales, Miguel A.; Cannell, Paul K.; Collins, Graham P.; Dürig, Jan; Forstpointner, Roswitha; Herold, Michael; Hertzberg, Mark; Klanova, Magdalena; Radford, John; Seymour, John F.; Tobinai, Kensei; Trotman, Judith; Burciu, Alis; Fingerle-Rowson, Günter; Wolbers, Marcel; Nielsen, Tina und Marcus, Robert E.
(2018):
Immunochemotherapy With Obinutuzumab or Rituximab for Previously Untreated Follicular Lymphoma in the GALLIUM Study: Influence of Chemotherapy on Efficacy and Safety.
In: Journal of Clinical Oncology, Bd. 36, Nr. 23: S. 2395-2404
[PDF, 904kB]
Rothenberg-Thurley, Maja; Amler, Susanne; Goerlich, Dennis; Köhnke, Thomas; Konstandin, Nikola P.; Schneider, Stephanie; Sauerland, Maria C.; Herold, Tobias; Hubmann, Max; Ksienzyk, Bianka; Zellmeier, Evelyn; Bohlander, Stefan K.; Subklewe, Marion; Faldum, Andreas; Hiddemann, Wolfgang; Braess, Jan; Spiekermann, Karsten und Metzeler, Klaus H.
(2018):
Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia.
In: Leukemia, Bd. 32, Nr. 7: S. 1598-1608
Lengfelder, Eva; Goerlich, Dennis; Nowak, Daniel; Spiekermann, Karsten; Haferlach, Claudia; Krug, Utz; Kreuzer, Karl-Anton; Braess, Jan; Schliemann, Christoph; Lindemann, Hans-Walter; Horst, Heinz A.; Schiel, Xaver; Flasshove, Michael; Hecht, Anna; Schnittger, Susanne; Schneider, Stephanie; Wörmann, Bernhard; Hofmann, Wolf-Karsten; Berdel, Wolfgang E.; Bormann, Eike; Sauerland, Cristina; Büchner, Thomas und Hiddemann, Wolfgang
(2018):
Frontline therapy of acute promyelocytic leukemia: Randomized comparison of ATRA and intensified chemotherapy versus ATRA and anthracyclines.
In: European Journal of Haematology, Bd. 100, Nr. 2: S. 154-162
Laryionava, Katsiaryna; Mehlis, Katja; Bierwirth, Elena; Mumm, Friederike; Hiddemann, Wolfgang; Heussner, Pia und Winkler, Eva C.
(2018):
Development and Evaluation of an Ethical Guideline for Decisions to Limit Life-Prolonging Treatment in Advanced Cancer: Protocol for a Monocentric Mixed-Method Interventional Study.
In: Jmir Research Protocols, Bd. 7, Nr. 6, e157
[PDF, 67kB]
Shi, Qian; Flowers, Christopher R.; Hiddemann, Wolfgang; Marcus, Robert; Herold, Michael; Hagenbeek, Anton; Kimby, Eva; Hochster, Howard; Vitolo, Umberto; Peterson, Bruce A.; Gyan, Emmanuel; Ghielmini, Michele; Nielsen, Tina; Bedout, Sabine de; Fu, Tommy; Valente, Nancy; Fowler, Nathan H.; Hoster, Eva; Ladetto, Marco; Morschhauser, Franck; Zucca, Emanuele; Salles, Gilles und Sargent, Daniel J.
(10. Februar 2017):
Thirty-Month Complete Response as a Surrogate End Point in First-Line Follicular Lymphoma Therapy: An Individual Patient-Level Analysis of Multiple Randomized Trials.
In: Journal of clinical oncology, Bd. 35, Nr. 5: S. 552-560
Herold, Tobias; Schneider, S.; Metzeler, Klaus H.; Neumann, Martin; Hartmann, Luise; Roberts, Kathryn G.; Konstandin, Nikola P.; Greif, Philipp A.; Bräundl, Kathrin; Ksienzyk, Bianka; Huk, Natalia; Schneider, Irene; Zellmeier, Evelyn; Jurinovic, Vindi; Mansmann, Ulrich; Hiddemann, Wolfgang; Mullighan, Charles G.; Bohlander, Stefan K.; Spiekermann, Karsten; Hölzel, Dieter; Brüggemann, Monika; Baldus, Claudia D.; Dreyling, Martin und Gökbuget, Nicola
(2017):
Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis.
In: Haematologica, Bd. 102, Nr. 1: S. 130-138
[PDF, 1MB]
Herold, Tobias; Metzeler, Klaus H.; Vosberg, Sebastian; Hartmann, Luise; Jurinovic, Vindi; Opatz, Sabrina; Konstandin, Nikola P.; Schneider, S.; Zellmeier, Evelyn; Ksienzyk, Bianka; Graf, A.; Krebs, S.; Blum, H.; Sauerland, Maria Cristina; Büchner, T.; Berdel, W. E.; Wörmann, Bernhard; Mansmann, Ulrich; Hiddemann, Wolfgang; Bohlander, Stefan K.; Spiekermann, Karsten und Greif, Philipp A.
(2017):
Acute Myeloid Leukemia with Del(9q) is Characterized by Frequent Mutations of NPM1, DNMT3A, WT1 and Low Expression of TLE4.
In: Genes, Chromosomes and Cancer, Bd. 56, Nr. 1: S. 75-86
Stevens, Wendy B. C.; Mendeville, Matias; Redd, Robert; Clear, Andrew J.; Bladergroen, Reno; Calaminici, Maria; Rosenwald, Andreas; Hoster, Eva; Hiddemann, Wolfgang; Gaulard, Philippe; Xerri, Luc; Salles, Gilles; Klapper, Wolfram; Pfreundschuh, Michael; Jack, Andrew; Gascoyne, Randy D.; Natkunam, Yasodha; Advani, Ranjana; Kimby, Eva; Sander, Birgitta; Sehn, Laurie H.; Hagenbeek, Anton; Raemaekers, John; Gribben, John; Kersten, Marie José; Ylstra, Bauke; Weller, Edie und Jong, Daphne de
(2017):
Prognostic relevance of CD163 and CD8 combined with EZH2 and gain of chromosome 18 in follicular lymphoma: a study by the Lunenburg Lymphoma Biomarker Consortium.
In: Haematologica, Bd. 102, Nr. 8: S. 1413-1423
Köhnke, Thomas; Wittmann, Veronika K.; Bücklein, Veit L.; Lichtenegger, Felix; Pasalic, Zlatana; Hiddemann, Wolfgang; Spiekermann, Karsten und Subklewe, Marion
(2017):
Diagnosis of CLL revisited: increased specificity by a modified five-marker scoring system including CD200.
In: British Journal of Haematology, Bd. 179, Nr. 3: S. 480-487
Krupka, Christina; Lichtenegger, Felix S.; Kohnke, Thomas; Bogeholz, Jan; Bucklein, Veit; Roiss, Michael; Altmann, Torben; Do, To Uyen; Dusek, Rachel; Wilson, Keith; Bisht, Arnima; Terrett, Jon; Aud, Dee; Pombo-Villar, Esteban; Rohlff, Christian; Hiddemann, Wolfgang und Subklewe, Marion
(2017):
Targeting CD157 in AML using a novel, Fc-engineered antibody construct.
In: Oncotarget, Bd. 8, Nr. 22: S. 35707-35717
[PDF, 1MB]
Mehlis, Katja; Becker, Christina; Christ, Carola; Laryionava, Katsiaryna; Hiddemann, Wolfgang; Heussner, Pia und Winkler, Eva Caroline
(2017):
Häufigkeit und Zeitpunkt von Entscheidungen gegen intensivmedizinische Maßnahmen und tumorspezifische Therapien in einer universitären Hämatologie und Onkologie.
In: Deutsche Medizinische Wochenschrift, Bd. 142, Nr. 17, E116-E123
Sandhöfer, Nadine; Metzeler, Klaus H.; Kakadia, Purvi M.; Pasalic, Zlatana; Hiddemann, Wolfgang; Neusser, Michaela; Steinlein, Ortrud; Fiegl, Michael; Subklewe, Marion; Spiekermann, Karsten; Bohlander, Stefan K.; Schneider, Stephanie und Bräss, Jan
(2017):
A fluorescence in situ hybridization-based screen allows rapid detection of adverse cytogenetic alterations in patients with acute myeloid leukemia.
In: Genes Chromosomes & Cancer, Bd. 56, Nr. 8: S. 632-638
Hecht, Anna; Doll, Seraphina; Altmann, Heidi; Nowak, Daniel; Lengfelder, Eva; Rollig, Christoph; Ehninger, Gerhard; Spiekermann, Karsten; Hiddemann, Wolfgang; Weiss, Christel; Hofmann, Wolf-Karsten; Nolte, Florian und Platzbecker, Uwe
(2017):
Validation of a Molecular Risk Score for Prognosis of Patients With Acute Promyelocytic Leukemia Treated With All-trans Retinoic Acid and Chemotherapy-containing Regimens.
In: Clinical Lymphoma Myeloma & Leukemia, Bd. 17, Nr. 12: S. 889-896
Cusan, Monica; Vegi, Naidu M.; Mulaw, Medhanie A.; Bamezai, Shiva; Kaiser, Lisa M.; Deshpande, Aniruddha J.; Greif, Philipp A.; Quintanilla-Fend, Leticia; Göllner, Stefanie; Müller-Tidow, Carsten; Humphries, Keith R.; Armstrong, Scott A.; Hiddemann, Wolfgang; Feuring-Buske, Michaela und Buske, Christian
(2017):
Controlled stem cell amplification by HOXB4 depends on its unique proline-rich region near the N terminus.
In: Blood, Bd. 129, Nr. 3: S. 319-323
Leich, E.; Hoster, Eva; Wartenberg, M.; Unterhalt, Michael; Siebert, R.; Koch, K.; Klapper, Wolfram; Engelhard, Marianne; Puppe, B.; Horn, Heike; Staiger, A. M.; Stuhlmann-Laeisz, C.; Bernd, Heinz Wolfram; Feller, A. C.; Hummel, Martina; Lenze, D.; Stein, H.; Hartmann, S.; Hansmann, Martin-Leo; Möller, P.; Hiddemann, Wolfgang; Dreyling, Martin; Ott, German und Rosenwald, Andreas
(2016):
Similar clinical features in follicular lymphomas with and without breaks in the BCL2 locus.
In: Leukemia, Bd. 30, Nr. 4: S. 854-860
Vosberg, Sebastian; Herold, Tobias; Hartmann, Luise; Neumann, Martin; Opatz, Sabrina; Metzeler, Klaus H.; Schneider, S.; Graf, A.; Krebs, S.; Blum, H.; Baldus, Claudia D.; Hiddemann, Wolfgang; Spiekermann, Karsten; Bohlander, Stefan K.; Mansmann, Ulrich und Greif, Philipp A.
(2016):
Close Correlation of Copy Number Aberrations Detected by Close correlation of copy number aberrations detected by next-generation sequencing with results from routine cytogenetics in acute myeloid leukemia.
In: Genes, Chromosomes and Cancer, Bd. 55, Nr. 7: S. 553-567
Hoster, Eva; Rosenwald, Andreas; Berger, F.; Bernd, Heinz Wolfram; Hartmann, S.; Loddenkemper, Christoph; Barth, Thomas E. F.; Brousse, N.; Pileri, S.; Rymkiewicz, G.; Kodet, Roman; Stilgenbauer, S.; Forstpointner, R.; Thieblemont, C.; Hallek, M.; Coiffier, B.; Vehling-Kaiser, U.; Bouabdallah, R.; Kanz, L.; Pfreundschuh, M.; Schmidt, C.; Ribrag, Vincent; Hiddemann, Wolfgang; Unterhalt, Michael; Kluin-Nelemans, J. C.; Hermine, Olivier; Dreyling, Martin und Klapper, Wolfram
(2016):
Prognostic Value of Ki-67 Index, Cytology, and Growth Pattern in Mantle-Cell Lymphoma: Results From Randomized Trials of the European Mantle Cell Lymphoma Network.
In: Journal of Clinical Oncology, Bd. 34, Nr. 12: S. 1386-1394
Koch, K.; Hoster, Eva; Ziepert, M.; Unterhalt, Michael; Ott, German; Rosenwald, Andreas; Hansmann, Martin-Leo; Bernd, W.; Stein, H.; Pöschel, V.; Dreyling, Martin; Trümper, L.; Löffler, M.; Schmitz, N.; Hiddemann, Wolfgang; Pfreundschuh, M. und Klapper, Wolfram
(2016):
Clinical, pathological and genetic features of follicular lymphoma grade 3A: a joint analysis of the German low-grade and high-grade lymphoma study groups GLSG and DSHNHL.
In: Annals of Oncology, Bd. 27, Nr. 7: S. 1323-1329
Kossak-Roth, U.; Saußele, Susanne; Aul, C.; Büchner, T.; Dohner, H.; Dugas, Martin; Ehninger, G.; Ganser, A.; Giagounidis, A.; Gökbuget, Nicola; Griesshammer, M.; Hasford, Joerg; Heuser, M.; Hiddemann, Wolfgang; Hochhaus, A.; Hoelzer, D.; Niederwieser, D. W.; Reiter, A.; Röllig, C. und Hehlmann, R.
(2016):
Entstehung, Entwicklung und Erfolge des Kompetenznetzes Akute und Chronische Leukämien (KNL).
In: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, Bd. 59, Nr. 4: S. 444-453
Jurinovic, Vindi; Kridel, R.; Staiger, A. M.; Szczepanowski, M.; Horn, Heike; Dreyling, Martin; Rosenwald, Andreas; Ott, German; Klapper, Wolfram; Zelenetz, A. D.; Barr, P. M.; Friedberg, J. W.; Ansell, S.; Sehn, L. H.; Connors, J. M.; Gascoyne, R. D.; Hiddemann, Wolfgang; Unterhalt, Michael; Weinstock, D. M. und Weigert, O.
(2016):
Clinicogenetic risk models predict early progression of follicular lymphoma after first-line immunochemotherapy.
In: Blood, Bd. 128, Nr. 8: S. 1112-1120
Hermine, Olivier; Hoster, Eva; Walewski, J.; Bosly, A.; Stilgenbauer, S.; Thieblemont, C.; Szymczyk, Michal; Bouabdallah, R.; Kneba, M.; Hallek, M.; Salles, G.; Feugier, P.; Ribrag, Vincent; Birkmann, J.; Forstpointner, R.; Haioun, C.; Hänel, M.; Casasnovas, R. O.; Finke, J.; Peter, N.; Bouabdallah, K.; Sebban, C.; Fischer, T.; Dührsen, U.; Metzner, B.; Maschmeyer, G.; Kanz, L.; Schmidt, C.; Delarue, R.; Brousse, N.; Klapper, Wolfram; Macintyre, E.; Delfau-Larue, M. H.; Pott, Christiane; Hiddemann, Wolfgang; Unterhalt, Michael und Dreyling, Martin
(2016):
Addition of high-dose cytarabine to immunochemotherapy before autologous stem-cell transplantation in patients aged 65 years or younger with mantle cell lymphoma (MCL Younger): a randomised, open-label, phase 3 trial of the European Mantle Cell Lymphoma Network.
In: Lancet, Bd. 388, Nr. 10044: S. 565-575
Harnicek, D.; Kampmann, E.; Lauber, K.; Hennel, R.; Cardoso Martins, A. S.; Guo, Y.; Belka, Claus; Mörtl, S.; Gallmeier, E.; Kanaar, R.; Mansmann, Ulrich; Hucl, T.; Lindner, L. H.; Hiddemann, Wolfgang und Issels, R. D.
(2016):
Hyperthermia adds to trabectedin effectiveness and thermal enhancement is associated with BRCA2 degradation and impairment of DNA homologous recombination repair.
In: International Journal of Cancer, Bd. 139, Nr. 2: S. 467-479
Pohlen, Michele; Thoennissen, Nils H.; Braess, Jan; Thudium, Johannes; Schmid, Christoph; Kochanek, Matthias; Kreuzer, Karl-Anton; Lebiedz, Pia; Görlich, Dennis; Gerth, Hans U.; Rohde, Christian; Kessler, Torsten; Müller-Tidow, Carsten; Stelljes, Matthias; Büchner, Thomas; Schlimok, Günter; Hallek, Michael; Waltenberger, Johannes; Hiddemann, Wolfgang; Berdel, Wolfgang E.; Heilmeier, Bernhard und Krug, Utz
(2016):
Patients with Acute Myeloid Leukemia Admitted to Intensive Care Units: Outcome Analysis and Risk Prediction.
In: PLOS ONE
11(8), e0160871
[PDF, 1MB]
Vegi, Naidu M.; Klappacher, Josef; Oswald, Franz; Mulaw, Medhanie A.; Mandoli, Amit; Thiel, Verena N.; Bamezai, Shiva; Feder, Kristin; Martens, Joost H. A.; Rawat, Vijay P. S.; Mandal, Tamoghna; Quintanilla-Martinez, Leticia; Spiekermann, Karsten; Hiddemann, Wolfgang; Döhner, Konstanze; Döhner, Hartmut; Stunnenberg, Hendrik G.; Feuring-Buske, Michaela und Buske, Christian
(2016):
MEIS2 Is an Oncogenic Partner in AML1-ETO-Positive AML.
In: Cell Reports, Bd. 16, Nr. 2: S. 498-507
[PDF, 10MB]
Sandhöfer, Nadine; Bauer, Julia; Reiter, Katrin; Dufour, Annika; Rothenberg, Maja; Konstandin, Nikola P.; Zellmeier, Evelyn; Tizazu, Belay; Greif, Philipp A.; Metzeler, Klaus H.; Hiddemann, Wolfgang; Polzer, Harald und Spiekermann, Karsten
(2016):
The new and recurrent FLT3 juxtamembrane deletion mutation shows a dominant negative effect on the wild-type FLT3 receptor.
In: Scientific Reports, Bd. 6, 28032
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Hartmann, Luise; Dutta, Sayantanee; Opatz, Sabrina; Vosberg, Sebastian; Reiter, Katrin; Leubolt, Georg; Metzeler, Klaus H.; Herold, Tobias; Bamopoulos, Stefanos A.; Bräundl, Kathrin; Zellmeier, Evelyn; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Hopfner, Karl-Peter; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Middeke, Jan Moritz; Stölzel, Friedrich; Thiede, Christian; Wolf, Stephan; Bohlander, Stefan K.; Preiss, Caroline; Chen-Wichmann, Linping; Wichmann, Christian; Sauerland, Maria Cristina; Büchner, Thomas; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Braess, Jan; Hiddemann, Wolfgang; Spiekermann, Karsten und Greif, Philipp A.
(2016):
ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
In: Nature Communications, Bd. 7, 11733
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Metzeler, Klaus H.; Herold, Tobias; Rothenberg-Thurley, Maja; Amler, Susanne; Sauerland, Maria C.; Görlich, Dennis; Schneider, Stephanie; Konstandin, Nikola P.; Dufour, Annika; Bräundl, Kathrin; Ksienzyk, Bianka; Zellmeier, Evelyn; Hartmann, Luise; Greif, Philipp A.; Fiegl, Michael; Subklewe, Marion; Bohlander, Stefan K.; Krug, Utz; Faldum, Andreas; Berdel, Wolfgang E.; Wörmann, Bernhard; Büchner, Thomas; Hiddemann, Wolfgang; Braess, Jan und Spiekermann, Karsten
(2016):
Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia.
In: Blood, Bd. 128, Nr. 5: S. 686-698
Krupka, Christina; Kufer, Peter; Kischel, Roman; Zugmaier, Gerhard; Köhnke, Thomas; Lichtenegger, Felix; Altmann, Torben; Spiekermann, Karsten; Vick, Binje; Jeremias, Irmela; Hiddemann, Wolfgang; Riethmüller, Gert und Subklewe, Marion
(2016):
Characterization of covariables modulating CD33/CD3 BITE antibody construct mediated cytotoxicity against primary AML cells.
In: Cancer Immunology Research, Bd. 4, Nr. 1
Lichtenegger, Felix S.; Schnorfeil, Frauke M.; Köhnke, Thomas; Altmann, Torben; Bücklein, Veit; Moosmann, Andreas; Brüggemann, Monika; Wagner, Beate; Hiddemann, Wolfgang; Bigalke, Iris; Kvalheim, Gunnar und Subklewe, Marion
(2016):
Next-generation dendritic cell vaccination in postremission therapy of AML: Results of a clinical phase I trial.
In: Cancer Immunology Research, Bd. 4, Nr. 1
Hubmann, Max; Fritsch, Susanne; Zoellner, Anna-Katharina; Prevalsek, Dusan; Engel, Nicole; Bücklein, Veit; Mumm, Friederike; Schulz, Christoph; Stemmler, Hans Joachim; Jäger, Gundula; Ledderose, Georg; Kolb, Hans Jochem; Hausmann, Andreas; Hiddemann, Wolfgang; Moosmann, Andreas und Tischer, Johanna
(2016):
Occurrence, risk factors and outcome of adenovirus infection in adult recipients of allogeneic hematopoietic stem cell transplantation.
In: Journal of Clinical Virology, Bd. 82: S. 33-40
Laverdière, Isabelle; Boileau, Meaghan; Herold, Tobias; Rak, Janusz; Berdel, Wolfgang E.; Wörmann, Bernhard; Hiddemann, Wolfgang; Spiekermann, Karsten; Bohlander, Stefan K. und Eppert, Kolja
(2016):
Complement cascade gene expression defines novel prognostic subgroups of acute myeloid leukemia.
In: Experimental Hematology, Bd. 44, Nr. 11: S. 1039-1043
Zoellner, Anna-Katharina; Fritsch, Susanne; Prevalsek, Dusan; Köhnke, Thomas; Hubmann, Max; Lippl, Stephanie; Kruger, Stephan; Hellmuth, Johannes; Mumm, Friederike; Ledderose, Georg; Barlow, Sophie; Subklewe, Marion; Spiekermann, Karsten; Hiddemann, Wolfgang; Albert, Michael H.; Schmid, Christoph; Hausmann, Andreas und Tischer, Johanna
(2016):
T-Cell-Replete HLA-Haploidentical Transplantation Using Post-Transplantation High-Dose Cyclophosphamide in High Risk and Advanced ALL: Feasibility and Early Outcome.
In: Biology of Blood and Marrow Transplantation, Bd. 22, Nr. 3:
S364-S364
Ng, Stanley W. K.; Mitchell, Amanda; Kennedy, James A.; Chen, Weihsu C.; McLeod, Jessica; Ibrahimova, Narmin; Arruda, Andrea; Popescu, Andreea; Gupta, Vikas; Schimmer, Aaron D.; Schuh, Andre C.; Yee, Karen W.; Bullinger, Lars; Herold, Tobias; Görlich, Dennis; Büchner, Thomas; Hiddemann, Wolfgang; Berdel, Wolfgang E.; Wörmann, Bernhard; Cheok, Meyling; Preudhomme, Claude; Dombret, Hervé; Metzeler, Klaus; Buske, Christian; Löwenberg, Bob; Valk, Peter J. M.; Zandstra, Peter W.; Minden, Mark D. .; Dick, John E. und Wang, Jean C. Y.
(2016):
A 17-gene stemness score for rapid determination of risk in acute leukaemia.
In: Nature, Bd. 540, Nr. 7633: S. 433-437
Niavarani, Ahmadreza; Herold, Tobias; Reyal, Yasmin; Sauerland, Maria C.; Buchner, Thomas; Hiddemann, Wolfgang; Bohlander, Stefan K.; Valk, Peter J. M. und Bonnet, Dominique
(2016):
A 4-gene expression score associated with high levels of Wilms Tumor-1 (WT1) expression is an adverse prognostic factor in acute myeloid leukaemia.
In: British Journal of Haematology, Bd. 172, Nr. 3: S. 401-411
Ebinger, Sarah; Özdemir, Erbey Ziya; Ziegenhain, Christoph; Tiedt, Sebastian; Castro Alves, Catarina; Grunert, Michaela; Dworzak, Michael; Lutz, Christoph; Turati, Virginia A.; Enver, Tariq; Horny, Hans-Peter; Sotlar, Karl; Parekh, Swati; Spiekermann, Karsten; Hiddemann, Wolfgang; Schepers, Aloys; Polzer, Bernhard; Kirsch, Stefan; Hoffmann, Martin; Knapp, Bettina; Hasenauer, Jan; Pfeifer, Heike; Panzer-Grümayer, Renate; Enard, Wolfgang; Gires, Olivier und Jeremias, Irmela
(2016):
Characterization of Rare, Dormant, and Therapy-Resistant Cells in Acute Lymphoblastic Leukemia.
In: Cancer Cell, Bd. 30, Nr. 6: S. 849-862
Pastore, A.; Jurinovic, Vindi; Kridel, R.; Hoster, Eva; Staiger, A. M.; Szczepanowski, M.; Pott, Christiane; Kopp, N.; Murakami, M.; Horn, Heike; Leich, E.; Moccia, A. A.; Mottok, A.; Sunkavalli, A.; van Hummelen, P.; Ducar, M.; Ennishi, D.; Shulha, H. P.; Hother, C.; Connors, J. M.; Sehn, L. H.; Dreyling, Martin; Neuberg, D.; Moller, P.; Feller, A. C.; Hansmann, Martin-Leo; Stein, H.; Rosenwald, Andreas; Ott, German; Klapper, Wolfram; Unterhalt, Michael; Hiddemann, Wolfgang; Gascoyne, R. D.; Weinstock, D. M. und Weigert, O.
(2015):
Integration of gene mutations in risk prognostication for patients receiving first-line immunochemotherapy for follicular lymphoma: a retrospective analysis of a prospective clinical trial and validation in a population-based registry.
In: Lancet Oncology, Bd. 16, Nr. 9: S. 1111-1122
Schemionek, Mirle; Masouleh, Behzad Kharabi; Klaile, Yvonne; Krug, Utz; Hebestreit, Katja; Schubert, Claudia; Dugas, Martin; Büchner, Thomas; Wörmann, Bernhard; Hiddemann, Wolfgang; Berdel, Wolfgang E.; Brümmendorf, Tim H.; Mueller-Tidow, Carsten und Koschmieder, Steffen
(2015):
Identification of the Adapter Molecule MTSS1 as a Potential Oncogene-Specific Tumor Suppressor in Acute Myeloid Leukemia.
In: PLOS ONE
10(5), e0125783
[PDF, 1MB]
Vick, Binje; Rothenberg, Maja; Sandhöfer, Nadine; Carlet, Michela; Finkenzeller, Cornelia; Krupka, Christina; Grunert, Michaela; Trumpp, Andreas; Corbacioglu, Selim; Ebinger, Martin; André, Maya C.; Hiddemann, Wolfgang; Schneider, Stephanie; Subklewe, Marion; Metzeler, Klaus H.; Spiekermann, Karsten und Jeremias, Irmela
(2015):
An Advanced Preclinical Mouse Model for Acute Myeloid Leukemia Using Patients' Cells of Various Genetic Subgroups and In Vivo Bioluminescence Imaging.
In: PLOS ONE
10(3), e0120925
[PDF, 3MB]
Pastore, Friederike; Kling, Daniela; Hoster, Eva; Dufour, Annika; Konstandin, Nikola P.; Schneider, Stephanie; Sauerland, Maria C.; Berdel, Wolfgang E.; Buechner, Thomas; Woermann, Bernhard; Braess, Jan; Hiddemann, Wolfgang und Spiekermann, Karsten
(2014):
Long-term follow-up of cytogenetically normal CEBPA-mutated AML.
In: Journal of Hematology & Oncology
7:55
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Pastore, Friederike; Greif, Philipp A.; Schneider, Stephanie; Ksienzyk, Bianka; Mellert, Gudrun; Zellmeier, Evelyn; Braess, Jan; Sauerland, Cristina M.; Heinecke, Achim; Krug, Utz; Berdel, Wolfgang E.; Buechner, Thomas; Woermann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2014):
The NPM1 Mutation Type Has No Impact on Survival in Cytogenetically Normal AML.
In: PLOS ONE
9(10), e109759
[PDF, 605kB]
Hubmann, Max; Köhnke, Thomas; Hoster, Eva; Schneider, Stephanie; Dufour, Annika; Zellmeier, Evelyn; Fiegl, Michael; Braess, Jan; Bohlander, Stefan K.; Subklewe, Marion; Sauerland, Maria-Cristina; Berdel, Wolfgang E.; Büchner, Thomas; Woermann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2014):
Molecular response assessment by quantitative real-time polymerase chain reaction after induction therapy in NPM1-mutated patients identifies those at high risk of relapse.
In: Haematologica, Bd. 99, Nr. 8: S. 1317-1325
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Janke, Hanna; Pastore, Friederike; Schumacher, Daniela; Herold, Tobias; Hopfner, Karl-Peter; Schneider, Stephanie; Berdel, Wolfgang E.; Büchner, Thomas; Woermann, Bernhard J.; Subklewe, Marion; Bohlander, Stefan K.; Hiddemann, Wolfgang; Spiekermann, Karsten und Polzer, Harald
(2014):
Activating FLT3 Mutants Show Distinct Gain-of-Function Phenotypes In Vitro and a Characteristic Signaling Pathway Profile Associated with Prognosis in Acute Myeloid Leukemia.
In: PLOS ONE
9(3), e89560
[PDF, 2MB]
Wetzler, Meir; Mrózek, Krzysztof; Kohlschmidt, Jessica; Dombret, Herve; Döhner, Hartmut; Pilorge, Sylvain; Krug, Utz; Carroll, Andrew J.; Larson, Richard A.; Marcucci, Guido; Hiddemann, Wolfgang; Büchner, Thomas und Bloomfield, Clara D.
(2014):
Intensive induction is effective in selected octogenarian acute myeloid leukemia patients: prognostic significance of karyotype and selected molecular markers used in the European LeukemiaNet classification.
In: Haematologica, Bd. 99, Nr. 2: S. 308-313
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Li, Z.; Herold, Tobias; He, C.; Valk, P. J.; Chen, P.; Jurinovic, Vindi; Mansmann, Ulrich; Radmacher, M. D.; Maharry, K. S.; Sun, M.; Yang, X.; Huang, H.; Jiang, X.; Sauerland, M. C.; Büchner, T.; Hiddemann, Wolfgang; Elkahloun, A.; Neilly, M. B.; Zhang, Y.; Larson, R. A.; Le Beau, M. M.; Caligiuri, M. A.; Dohner, K.; Bullinger, L.; Liu, P. P.; Delwel, R.; Marcucci, G.; Lowenberg, B.; Bloomfield, C. D.; Rowley, J. D.; Bohlander, Stefan K. und Chen, J.
(2013):
Identification of a 24-Gene Prognostic Signature That Improves the European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: An International Collaborative Study.
In: Journal of Clinical Oncology, Bd. 31, Nr. 9: S. 1172-1181
Schneider, F.; Hoster, Eva; Schneider, S.; Dufour, A.; Benthaus, T.; Kakadia, P. M.; Bohlander, Stefan K.; Braess, J.; Heinecke, A.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Feuring-Buske, M.; Buske, C.; Creutzig, U.; Thiede, C.; Zwaan, M. C.; Heuvel-Eibrink, M. M. van den; Reinhardt, D.; Hiddemann, Wolfgang und Spiekermann, Karsten
(2012):
Age-dependent frequencies of NPM1 mutations and FLT3-ITD in patients with normal karyotype AML (NK-AML).
In: Annals of Hematology, Bd. 91, Nr. 1: S. 9-18
Schneider, F.; Hoster, Eva; Unterhalt, Michael; Schneider, S.; Dufour, A.; Benthaus, T.; Mellert, G.; Zellmeier, Evelyn; Kakadia, P. M.; Bohlander, Stefan K.; Feuring-Buske, M.; Buske, C.; Braess, J.; Heinecke, A.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2012):
The FLT3ITD level has a high prognostic impact in NPM1 mutated, but not NPM1 unmutated AML with a normal karyotype.
In: Blood, Bd. 119, Nr. 19: S. 4383-4386
Dufour, A.; Schneider, F.; Hoster, Eva; Benthaus, T.; Ksienzyk, Bianka; Schneider, S.; Kakadia, P. M.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Braess, J.; Subklewe, M.; Hiddemann, Wolfgang; Bohlander, Stefan K. und Spiekermann, Karsten
(2012):
Monoallelic CEBPA mutations in normal karyotype acute myeloid leukemia: independent favorable prognostic factor within NPM1 mutated patients.
In: Annals of Hematology, Bd. 91, Nr. 7: S. 1051-1063
Büchner, T.; Schlenk, R. F.; Schaich, M.; Doehner, K.; Krahl, R.; Krauter, J.; Heil, G.; Krug, U.; Sauerland, M. C.; Heinecke, A.; Späth, Daniela; Kramer, M.; Scholl, S.; Berdel, W. E.; Hiddemann, Wolfgang; Hoelzer, D.; Hehlmann, R.; Hasford, Joerg; Hoffmann, V. S.; Doehner, H.; Ehninger, G.; Ganser, A.; Niederwieser, D. W. und Pfirrmann, Markus
(2012):
Acute Myeloid Leukemia (AML): Different Treatment Strategies Versus a Common Standard Arm‐Combined Prospective Analysis by the German AML Intergroup.
In: Journal of Clinical Oncology, Bd. 30, Nr. 29: S. 3604-3610
Kluin-Nelemans, H. C.; Hoster, Eva; Hermine, Olivier; Walewski, J.; Trneny, Marek; Geisler, C. H.; Stilgenbauer, S.; Thieblemont, C.; Vehling-Kaiser, U.; Doorduijn, J. K.; Coiffier, B.; Forstpointner, R.; Tilly, H.; Kanz, L.; Feugier, P.; Szymczyk, Michal; Hallek, M.; Kremers, S.; Lepeu, G.; Sanhes, L.; Zijlstra, J. M.; Bouabdallah, R.; Lugtenburg, P. J.; Macro, M.; Pfreundschuh, M.; Prochazka, V.; Di Raimondo, F.; Ribrag, Vincent; Uppenkamp, M.; Andre, M.; Klapper, Wolfram; Hiddemann, Wolfgang; Unterhalt, Michael und Dreyling, Martin
(2012):
Treatment of older patients with mantle-cell lymphoma.
In: New England Journal of Medicine / NEJM, Bd. 367, Nr. 6: S. 520-531
Koch, K.; Hoster, Eva; Unterhalt, Michael; Ott, German; Rosenwald, Andreas; Hansmann, Martin-Leo; Engelhard, Marianne; Hiddemann, Wolfgang und Klapper, Wolfram
(2012):
The composition of the microenvironment in follicular lymphoma is associated with the stage of the disease.
In: Human Pathology, Bd. 43, Nr. 12: S. 2274-2281
Greif, Philipp A.; Dufour, A.; Konstandin, Nikola P.; Ksienzyk, Bianka; Zellmeier, Evelyn; Tizazu, B.; Sturm, J.; Benthaus, T.; Herold, Tobias; Yaghmaie, M.; Dorge, P.; Hopfner, K. P.; Hauser, A.; Graf, A.; Krebs, S.; Blum, H.; Kakadia, P. M.; Schneider, S.; Hoster, Eva; Schneider, F.; Stanulla, M.; Braess, J.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Hiddemann, Wolfgang; Spiekermann, Karsten und Bohlander, Stefan K.
(2012):
GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia.
In: Blood, Bd. 120, Nr. 2: S. 395-403
Herold, Tobias; Mulaw, M. A.; Jurinovic, Vindi; Seiler, T.; Metzeler, Klaus H.; Dufour, A.; Schneider, S.; Kakadia, P. M.; Spiekermann, Karsten; Mansmann, Ulrich; Hiddemann, Wolfgang; Buske, C.; Dreyling, Martin und Bohlander, Stefan K.
(2012):
High expression of MZB1 predicts adverse prognosis in chronic lymphocytic leukemia, follicular lymphoma and diffuse large B-cell lymphoma and is associated with a unique gene expression signature.
In: Leukemia & Lymphoma, Bd. 54, Nr. 8: S. 1652-1657
Herold, Tobias; Jurinovic, Vindi; Metzeler, Klaus H.; Boulesteix, Anne-Laure; Bergmann, M.; Seiler, T.; Mulaw, M.; Thoene, S.; Dufour, A.; Pasalic, Z.; Schmidberger, Markus; Schmidt, M.; Schneider, S.; Kakadia, P. M.; Feuring-Buske, M.; Braess, J.; Spiekermann, Karsten; Mansmann, Ulrich; Hiddemann, Wolfgang; Buske, C. und Bohlander, Stefan K.
(2011):
An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia.
In: Leukemia, Bd. 25, Nr. 10: S. 1639-1645
Herold, Tobias; Jurinovic, Vindi; Mulaw, M.; Seiler, T.; Dufour, A.; Schneider, S.; Kakadia, P. M.; Feuring-Buske, M.; Braess, J.; Spiekermann, Karsten; Mansmann, Ulrich; Hiddemann, Wolfgang; Buske, C. und Bohlander, Stefan K.
(2011):
Expression analysis of genes located in the minimally deleted regions of 13q14 and 11q22-23 in chronic lymphocytic leukemia-unexpected expression pattern of the RHO GTPase activator ARHGAP20.
In: Genes, Chromosomes and Cancer, Bd. 50, Nr. 7: S. 546-558
Pott, Christiane; Hoster, Eva; Delfau-Larue, M. H.; Beldjord, K.; Böttcher, S.; Asnafi, V.; Plonquet, A.; Siebert, R.; Callet-Bauchu, E.; Andersen, N.; van Dongen, J. J.; Klapper, Wolfram; Berger, F.; Ribrag, Vincent; van Hoof, A. L.; Trneny, Marek; Walewski, J.; Dreger, P.; Unterhalt, Michael; Hiddemann, Wolfgang; Kneba, M.; Kluin-Nelemans, H. C.; Hermine, Olivier; Macintyre, E. und Dreyling, Martin
(2010):
Molecular remission is an independent predictor of clinical outcome in patients with mantle cell lymphoma after combined immunochemotherapy: a European MCL intergroup study.
In: Blood, Bd. 115, Nr. 16: S. 3215-3223
Dufour, A.; Schneider, F.; Metzeler, Klaus H.; Hoster, Eva; Schneider, S.; Zellmeier, Evelyn; Benthaus, T.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Braess, J.; Hiddemann, Wolfgang; Bohlander, Stefan K. und Spiekermann, Karsten
(2010):
Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome.
In: Journal of Clinical Oncology, Bd. 28, Nr. 4: S. 570-577
Issels, R. D.; Lindner, L. H.; Verweij, J.; Wust, P.; Reichardt, P.; Schem, B. C.; Abdel-Rahman, S.; Daugaard, S.; Salat, C.; Wendtner, C. M.; Vujaskovic, Z.; Wessalowski, R.; Jauch, K. W.; Durr, H. R.; Ploner, F.; Baur-Melnyk, Andrea; Mansmann, Ulrich; Hiddemann, Wolfgang; Blay, J. Y. und Hohenberger, P.
(2010):
Neo-adjuvant chemotherapy alone or with regional hyperthermia for localised high-risk soft-tissue sarcoma: a randomised phase 3 multicentre study.
In: Lancet Oncology, Bd. 11, Nr. 6: S. 561-570
Milani, Valeria; Stangl, Stefan; Issels, Rolf; Gehrmann, Mathias; Wagner, Beate; Hube, Kathrin; Mayr, Doris; Hiddemann, Wolfgang; Molls, Michael und Multhoff, Gabriele
(2009):
Anti-tumor activity of patient-derived NK cells after cell-based immunotherapy - a case report.
In: Journal of Translational Medicine
7:50
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Metzeler, Klaus H.; Dufour, Annika; Benthaus, Tobias; Hummel, Manuela; Sauerland, Maria-Cristina; Heinecke, Achim; Berdel, Wolfgang E.; Büchner, Thomas; Woermann, Bernhard; Mansmann, Ulrich; Braess, Jan; Spiekermann, Karsten; Hiddemann, Wolfgang; Buske, Christian und Bohlander, Stefan K.
(2009):
ERG expression is an independent prognostic factor and allows refined risk stratification in cytogenetically normal acute myeloid leukemia: A comprehensive analysis of ERG, MN1, and BAALC transcript levels using oligonucleotide microarrays.
In: Journal of Clinical Oncology, Bd. 27, Nr. 30: S. 5031-5038
Metzeler, Klaus H.; Dufour, A.; Benthaus, T.; Hummel, Martina; Sauerland, M. C.; Heinecke, A.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Mansmann, Ulrich; Braess, J.; Spiekermann, Karsten; Hiddemann, Wolfgang; Buske, C. und Bohlander, Stefan K.
(2009):
ERG Expression Is an Independent Prognostic Factor and Allows Refined Risk Stratification in Cytogenetically Normal Acute Myeloid Leukemia: A Comprehensive Analysis of ERG, MN1, and BAALC Transcript Levels Using Oligonucleotide Microarrays.
In: Journal of Clinical Oncology, Bd. 27, Nr. 30: S. 5031-5038
Thoene, S.; Rawat, V. P.; Heilmeier, B.; Hoster, Eva; Metzeler, Klaus H.; Herold, Tobias; Hiddemann, Wolfgang; Gökbuget, Nicola; Hoelzer, D.; Bohlander, Stefan K.; Feuring-Buske, M. und Buske, C.
(2009):
The homeobox gene CDX2 is aberrantly expressed and associated with an inferior prognosis in patients with acute lymphoblastic leukemia.
In: Leukemia, Bd. 23, Nr. 4: S. 649-655
Reiff, T.; Stingele, R.; Eckstein, H. H.; Fraedrich, G.; Jansen, O.; Mudra, H.; Mansmann, Ulrich; Hacke, W.; Ringleb, P. A.; Metzeler, Klaus H.; Dufour, A.; Benthaus, T.; Hummel, Martina; Sauerland, M. C.; Heinecke, A.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Braess, J.; Spiekermann, Karsten; Hiddemann, Wolfgang; Buske, C.; Bohlander, Stefan K.; Nagel, J. M.; Wegscheider, K.; Rohmel, J.; Fleckenstein, M.; Adrion, Christine ORCID: https://orcid.org/0000-0003-2408-2533; Schmitz-Valckenberg, S.; Gobel, A. P.; Bindewald-Wittich, A.; Scholl, H. und Holz, F.
(2009):
Stent-Protected Angioplasty in Asymptomatic Carotid Artery Stenosis vs. Endarterectomy: SPACE2 – a Three-Arm Randomised-Controlled Clinical Trial.
In: International Journal of Stroke, Bd. 4, Nr. 4: S. 294-299
Schneider, F.; Hoster, Eva; Unterhalt, Michael; Schneider, S.; Dufour, A.; Benthaus, T.; Mellert, G.; Zellmeier, Evelyn; Bohlander, Stefan K.; Feuring-Buske, M.; Buske, C.; Braess, J.; Fritsch, S.; Heinecke, A.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2009):
NPM1, but not FLT3-ITD mutations predict early blast cell clearance and CR rate in patients with normal karyotype AML (NK-AML) or high risk myelodysplastic syndrome (MDS).
In: Blood, Bd. 113, Nr. 21: S. 5250-5253
Buske, C.; Hoster, Eva; Dreyling, Martin; Eimermacher, H.; Wandt, H.; Metzner, B.; Fuchs, R.; Bittenbring, J.; Wörmann, Bernhard; Hohloch, K.; Hess, G.; Ludwig, W. D.; Schimke, J.; Schmitz, S.; Kneba, M.; Reiser, M.; Graeven, U.; Klapper, Wolfram; Unterhalt, Michael und Hiddemann, Wolfgang
(2009):
The addition of rituximab to front-line therapy with CHOP (R-CHOP) results in a higher response rate and longer time to treatment failure in patients with lymphoplasmacytic lymphoma: results of a randomized trial of the German Low-Grade Lymphoma Study Group (GLSG).
In: Leukemia, Bd. 23, Nr. 1: S. 153-161
Klapper, Wolfram; Hoster, Eva; Determann, Olaf; Oschlies, Ilske; Laak, Jeroen van der; Berger, F.; Bernd, Heinz Wolfram; Cabeçadas, José; Campo, Elias; Cogliatti, Sergio; Hansmann, Martin-Leo; Kluin, Philip M.; Kodet, Roman; Krivolapov, Yuri A.; Loddenkemper, Christoph; Stein, H.; Moeller, P.; Barth, Thomas E. F.; Mueller-Hermelink, K.; Rosenwald, Andreas; Pileri, S.; Ralfkiaer, E.; Rymkiewicz, G.; Krieken, Johan H. van; Wacker, Hans Heinrich; Unterhalt, Michael; Hiddemann, Wolfgang und Dreyling, Martin
(2009):
Ki-67 as a prognostic marker in mantle cell lymphoma-consensus guidelines of the pathology panel of the European MCL Network.
In: Journal of Hematopathology, Bd. 2, Nr. 2: S. 103-111
Herrmann, Annina; Hoster, Eva; Zwingers, T.; Brittinger, G.; Engelhard, Marianne; Meusers, P.; Reiser, M.; Forstpointner, R.; Metzner, B.; Peter, N.; Wörmann, Bernhard; Trümper, L.; Pfreundschuh, M.; Einsele, H.; Hiddemann, Wolfgang; Unterhalt, Michael und Dreyling, Martin
(2009):
Improvement of overall survival in advanced stage mantle cell lymphoma.
In: Journal of Clinical Oncology, Bd. 27, Nr. 4: S. 511-518
Metzeler, Klaus H.; Hummel, Martina; Bloomfield, C. D.; Spiekermann, Karsten; Braess, J.; Sauerland, M. C.; Heinecke, A.; Radmacher, M. D.; Marcucci, G.; Whitman, SP.; Maharry, K.; Paschka, P.; Larson, RA.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Mansmann, Ulrich; Hiddemann, Wolfgang; Bohlander, Stefan K. und Buske, C.
(2008):
An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia.
In: Blood, Bd. 112, Nr. 10: S. 4193-4201
Schmid, C.; Schleuning, M.; Hentrich, M.; Markl, G. E.; Gerbitz, A.; Tischer, J.; Ledderose, G.; Oruzio, D.; Hiddemann, Wolfgang und Kolb, H. J.
(2008):
High antileukemic efficacy of an intermediate intensity conditioning regimen for allogeneic stem cell transplantation in patients with high-risk acute myeloid leukemia in first complete remission.
In: Bone Marrow Transplantation, Bd. 41, Nr. 8: S. 721-727
Determann, Olaf; Hoster, Eva; Ott, German; Wolfram-Bernd, H.; Loddenkemper, Christoph; Hansmann, Martin-Leo; Barth, Thomas E. F.; Unterhalt, Michael; Hiddemann, Wolfgang; Dreyling, Martin und Klapper, Wolfram
(2008):
Ki-67 predicts outcome in advanced-stage mantle cell lymphoma patients treated with anti-CD20 immunochemotherapy: results from randomized trials of the European MCL Network and the German Low Grade Lymphoma Study Group.
In: Blood, Bd. 111, Nr. 4: S. 2385-2387
Böttcher, S.; Ritgen, M.; Buske, S.; Gesk, S.; Klapper, Wolfram; Hoster, Eva; Hiddemann, Wolfgang; Unterhalt, Michael; Dreyling, Martin; Siebert, R.; Kneba, M. und Pott, Christiane
(2008):
Minimal residual disease detection in mantle cell lymphoma: methods and significance of four-color flow cytometry compared to consensus IGH-polymerase chain reaction at initial staging and for follow-up examinations.
In: Haematologica, Bd. 93, Nr. 4: S. 551-559
Hoster, Eva; Dreyling, Martin; Klapper, Wolfram; Gisselbrecht, C.; van Hoof, A.; Kluin-Nelemans, H. C.; Pfreundschuh, M.; Reiser, M.; Metzner, B.; Einsele, H.; Peter, N.; Jung, W.; Wörmann, Bernhard; Ludwig, W. D.; Dührsen, U.; Eimermacher, H.; Wandt, H.; Hasford, Joerg; Hiddemann, Wolfgang und Unterhalt, Michael
(2008):
A new prognostic index (MIPI) for patients with advanced-stage mantle cell lymphoma, Erratum.
In: Blood, Bd. 111, Nr. 2: S. 558-565
Nickenig, C.; Dreyling, Martin; Hoster, Eva; Ludwig, W. D.; Dörken, B.; Freund, M.; Huber, C.; Ganser, A.; Trümper, L.; Forstpointner, R.; Unterhalt, Michael und Hiddemann, Wolfgang
(2007):
Initial chemotherapy with mitoxantrone, chlorambucil, prednisone impairs the collection of stem cells in patients with indolent lymphomas: Results of a randomized comparison by the German Low-Grade Lymphoma Study Group.
In: Annals of Oncology, Bd. 18, Nr. 1: S. 136-142
Klapper, Wolfram; Hoster, Eva; Rolver, L.; Schrader, C.; Janssen, D.; Tiemann, M.; Bernd, Heinz Wolfram; Determann, Olaf; Hansmann, Martin-Leo; Möller, P.; Feller, A.; Stein, H.; Wacker, Hans Heinrich; Dreyling, Martin; Unterhalt, Michael; Hiddemann, Wolfgang und Ott, German
(2007):
Tumor sclerosis but not cell proliferation or malignancy grade is a prognostic marker in advanced-stage follicular lymphoma: the German Low Grade Lymphoma Study Group.
In: Journal of Clinical Oncology, Bd. 25, Nr. 22: S. 3330-3336
Schlemmer, Marcus; Wendtner, Clemens-Martin; Falk, Martin; Abdel-Rahman, Sultan; Licht, Thomas; Baumert, Jens; Straka, Christian; Hentrich, Marcus; Salat, Christoph; Hiddemann, Wolfgang und Issels, Rolf-Dieter
(2006):
Efficacy of consolidation high-dose chemotherapy with ifosfamide, carboplatin and etoposide (HD-ICE) followed by autologous peripheral blood stem cell rescue in chemosensitive patients with metastatic soft tissue sarcomas.
In: Oncology, Nr. 1-2: S. 32-39
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Nickenig, C.; Dreyling, Martin; Hoster, Eva; Pfreundschuh, M.; Trumper, L.; Reiser, M.; Wandt, H.; Lengfelder, E.; Unterhalt, Michael und Hiddemann, Wolfgang
(2006):
Combined cyclophosphamide, vincristine, doxorubicin, and prednisone (CHOP) improves response rates but not survival and has lower hematologic toxicity compared with combined mitoxantrone, chlorambucil, and prednisone (MCP) in follicular and mantle cell lymphomas: results of a prospective randomized trial of the German Low-Grade Lymphoma Study Group.
In: Cancer, Bd. 107, Nr. 5: S. 1014-1022
Buske, C.; Hoster, Eva; Dreyling, Martin; Hasford, Joerg; Unterhalt, Michael und Hiddemann, Wolfgang
(2006):
The Follicular Lymphoma International Prognostic Index (FLIPI) separates high-risk from intermediate- or low-risk patients with advanced-stage follicular lymphoma treated front-line with rituximab and the combination of cyclophosphamide, doxorubicin, vinc.
In: Blood, Bd. 108, Nr. 5: S. 1504-1508
Lenz, G.; Dreyling, Martin; Hoster, Eva; Wörmann, Bernhard; Dührsen, U.; Metzner, B.; Eimermacher, H.; Neubauer, A.; Wandt, H.; Steinhauer, H.; Martin, S.; Heidemann, E.; Aldaoud, A.; Parwaresch, R.; Hasford, Joerg; Unterhalt, Michael und Hiddemann, Wolfgang
(2005):
Immunochemotherapy with rituximab and cyclophosphamide, doxorubicin, vincristine, and prednisone significantly improves response and time to treatment failure, but not long-term outcome in patients with previously untreated mantle cell lymphoma: results of a prospective randomized trial of the German Low Grade Lymphoma Study Group (GLSG).
In: Journal of Clinical Oncology, Bd. 23, Nr. 23: S. 1984-1992
Schoch, C.; Kohlmann, A.; Dugas, Martin; Kern, W.; Hiddemann, Wolfgang; Schnittger, S. und Haferlach, T.
(2005):
Genomic gains and losses influence expression levels of genes located within the affected regions: a study on acute myeloid leukemias with trisomy 8, 11, or 13, monosomy 7, or deletion 5q.
In: Leukemia, Bd. 19, Nr. 7: S. 1224-1228
Dreyling, Martin; Lenz, G.; Hoster, Eva; Van-Hoof, A.; Gisselbrecht, C.; Schmits, R.; Metzner, B.; Truemper, L.; Reiser, M.; Steinhauer, H.; Boiron, J. M.; Boogaerts, M. A.; Aldaoud, A.; Silingardi, V.; Kluin-Nelemans, H. C.; Hasford, Joerg; Parwaresch, R.; Unterhalt, Michael und Hiddemann, Wolfgang
(2005):
Early consolidation by myeloablative radiochemotherapy followed by autologous stem cell transplantation in first remission significantly prolongs progression-free survival in mantle-cell lymphoma: results of a prospective randomized trial of the European MCL Network.
In: Blood, Bd. 105, Nr. 7: S. 2677-2684
Kohlmann, A.; Schoch, C.; Dugas, Martin; Schnittger, S.; Hiddemann, Wolfgang; Kern, W. und Haferlach, T.
(2005):
New insights into MLL gene rearranged acute leukemias using gene expression profiling: shared pathways, lineage commitment, and partner genes.
In: Leukemia, Bd. 19, Nr. 6: S. 953-964
Haferlach, T.; Kohlmann, A.; Schnittger, S.; Dugas, Martin; Hiddemann, Wolfgang; Kern, W. und Schoch, C.
(2005):
AML M3 and AML M3 variant each have a distinct gene expression signature but also share patterns different from other genetically defined AML subtypes.
In: Genes, Chromosomes and Cancer, Bd. 43, Nr. 2: S. 113-127
Lenz, G.; Dreyling, Martin; Schiegnitz, E.; Forstpointner, R.; Wandt, H.; Freund, M.; Hess, G.; Truemper, L.; Diehl, V.; Kropff, M.; Kneba, M.; Schmitz, N.; Metzner, B.; Pfirrmann, Markus; Unterhalt, Michael und Hiddemann, Wolfgang
(2004):
Myeloablative radiochemotherapy followed by autologous stem cell transplantation in first remission prolongs progression-free survival in follicular lymphoma: results of a prospective, randomized trial of the German Low-Grade Lymphoma Study Group.
In: Blood, Bd. 104, Nr. 9: S. 2667-2674
Schoch, C.; Schnittger, S.; Kern, W.; Dugas, Martin; Hiddemann, Wolfgang und Haferlach, T.
(2003):
Acute myeloid leukemia with recurring chromosome abnormalities as defined by the WHO-classification: incidence of subgroups, additional genetic abnormalities, FAB subtypes and age distribution in an unselected series of 1,897 patients with acute myeloid leukemia.
In: Haematologica, Bd. 88, Nr. 3: S. 351-352
Kohlmann, A.; Schoch, C.; Schnittger, S.; Dugas, Martin; Hiddemann, Wolfgang; Kern, W. und Haferlach, T.
(2003):
Molecular characterization of acute leukemias by use of microarray technology.
In: Genes, Chromosomes and Cancer, Bd. 37, Nr. 4: S. 396-405
Karthaus, M.; Buchheidt, D.; Hiddemann, Wolfgang; Donnelly, J. P.; Krcmery, V.; Schiel, X.; Wilhelm, M. und Helmerking, M.
(1999):
European surveillance of infections in cancer patients - ESIC.
In: Chemotherapy, Nr. 4: S. 237-241
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