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Anzahl der Publikationen: 115

2022

Murenu, Elisa; Gerhardt, Maximilian-Joachim; Biel, Martin und Michalakis, Stylianos (29. November 2022): More than meets the eye: The role of microglia in healthy and diseased retina. In: Frontiers in Immunology, Bd. 13 [PDF, 1MB]

Scotto Rosato, Anna; Krogsaeter, Einar K; Jaślan, Dawid; Abrahamian, Carla; Montefusco, Sandro; Soldati, Chiara; Spix, Barbara; Pizzo, Maria Teresa; Grieco, Giuseppina; Böck, Julia; Wyatt, Amanda; Wünkhaus, Daniela; Passon, Marcel; Stieglitz, Marc; Keller, Marco; Hermey, Guido; Markmann, Sandra; Gruber‐Schoffnegger, Doris; Cotman, Susan; Johannes, Ludger; Crusius, Dennis; Boehm, Ulrich; Wahl-Schott, Christian; Biel, Martin; Bracher, Franz; De Leonibus, Elvira; Polishchuk, Elena; Medina, Diego L; Paquet, Dominik und Grimm, Christian (5. August 2022): TPC2 rescues lysosomal storage in mucolipidosis type IV , Niemann–Pick type C1, and Batten disease. In: EMBO Molecular Medicine, Bd. 14, Nr. 9 [PDF, 27MB]

Spix, Barbara; Butz, Elisabeth S.; Chen, Cheng-Chang; Rosato, Anna Scotto; Tang, Rachel; Jeridi, Aicha; Kudrina, Veronika; Plesch, Eva; Wartenberg, Philipp; Arlt, Elisabeth; Briukhovetska, Daria; Ansari, Meshal; Günsel, Gizem Günes; Conlon, Thomas M.; Wyatt, Amanda; Wetzel, Sandra; Teupser, Daniel; Holdt, Lesca M.; Ectors, Fabien; Boekhoff, Ingrid; Boehm, Ulrich; García-Añoveros, Jaime; Saftig, Paul; Giera, Martin; Kobold, Sebastian; Schiller, Herbert B.; Zierler, Susanna; Gudermann, Thomas; Wahl-Schott, Christian; Bracher, Franz; Yildirim, Ali Önder; Biel, Martin und Grimm, Christian (2022): Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice. In: Nature Communications, Bd. 13, 318 [PDF, 3MB]

Hennis, Konstantin; Biel, Martin; Fenske, Stefanie und Wahl-Schott, Christian (2022): Paradigm shift: new concepts for HCN4 function in cardiac pacemaking. In: Pflugers Archiv-European Journal of Physiology, Bd. 474, Nr. 7: S. 649-663 [PDF, 4MB]

Rieser, Ruth; Menzen, Tim; Biel, Martin; Michalakis, Stylianos und Winter, Gerhard (2022): Systematic Studies on Stabilization of AAV Vector Formulations by Lyophilization. In: Journal of Pharmaceutical Sciences, Bd. 111, Nr. 8: S. 2288-2298

Hennis, Konstantin; Roetzer, Rene D.; Rilling, Julia; Wu, Yakun; Thalhammer, Stefan B.; Biel, Martin; Wahl-Schott, Christian und Fenske, Stefanie (2022): In vivo and ex vivo electrophysiological study of the mouse heart to characterize the cardiac conduction system, including atrial and ventricular vulnerability. In: Nature Protocols, Bd. 17, Nr. 5: S. 1189-1222

Siow, Wei Xiong; Kabiri, Yaschar; Tang, Rachel; Chao, Yu-Kai; Plesch, Eva; Eberhagen, Carola; Flenkenthaler, Florian; Froehlich, Thomas; Bracher, Franz; Grimm, Christian; Biel, Martin; Zischka, Hans; Vollmar, Angelika M. und Bartel, Karin (2022): Lysosomal TRPML1 regulates mitochondrial function in hepatocellular carcinoma cells. In: Journal of Cell Science, Bd. 135, Nr. 6, jcs259455

Chen, Cheng-Chang; Krogsaeter, Einar; Kuo, Ching-Ying; Huang, Min-Chuan; Chang, Sui-Yuan und Biel, Martin (2022): Endolysosomal cation channels point the way towards precision medicine of cancer and infectious diseases. In: Biomedicine & Pharmacotherapy, Bd. 148, 112751

Kandaswamy, Surabhi; Zobel, Lena; John, Bina; Santhiya, Sathiyaveedu Thyagarajan; Bogedein, Jacqueline; Przemeck, Gerhard K. H.; Gailus-Durner, Valerie; Fuchs, Helmut; Biel, Martin; Hrabě de Angelis, Martin; Graw, Jochen; Michalakis, Stylianos und Amarie, Oana Veronica (2022): Mutations within the cGMP-binding domain of CNGA1 causing autosomal recessive retinitis pigmentosa in human and animal model. In: Cell Death Discovery, Bd. 8, Nr. 1, 387

Esfandyari, Dena; Idrissou, Bio Maria Gheo; Hennis, Konstantin; Avramopoulos, Petros; Dueck, Anne; El-Battrawy, Ibrahim; Grueter, Laurenz; Meier, Melanie Annemarie; Naeger, Anna Christina; Ramanujam, Deepak; Dorn, Tatjana; Meitinger, Thomas; Hagl, Christian; Milting, Hendrik; Borggrefe, Martin; Fenske, Stefanie; Biel, Martin; Dendorfer, Andreas; Sassi, Yassine; Moretti, Alessandra und Engelhardt, Stefan (2022): MicroRNA-365 regulates human cardiac action potential duration. In: Nature Communications, Bd. 13, Nr. 1, 220

Spix, Barbara; Castiglioni, Andrew J.; Remis, Natalie N.; Flores, Emma N.; Wartenberg, Philipp; Wyatt, Amanda; Boehm, Ulrich; Gudermann, Thomas; Biel, Martin; Garcia-Anoveros, Jaime und Grimm, Christian (2022): Whole-body analysis of TRPML3 (MCOLN3) expression using a GFP-reporter mouse model reveals widespread expression in secretory cells and endocrine glands.
In: PLOS One 17(12), e0278848

2021

Hennis, Konstantin; Roetzer, Rene D.; Piantoni, Chiara; Biel, Martin; Wahl-Schott, Christian und Fenske, Stefanie (27. Mai 2021): Speeding Up the Heart? Traditional and New Perspectives on HCN4 Function. In: Frontiers in Physiology, Bd. 12, 669029 [PDF, 4MB]

Netcharoensirisuk, Ponsawan; Abrahamian, Carla; Tang, Rachel; Chen, Cheng-Chang; Rosato, Anna Scotto; Beyers, Wyatt; Chao, Yu-Kai; Filippini, Antonio; Di Pietro, Santiago; Bartel, Karin; Biel, Martin; Vollmar, Angelika M.; Umehara, Kaoru; De-Eknamkul, Wanchai und Grimm, Christian (2021): Flavonoids increase melanin production and reduce proliferation, migration and invasion of melanoma cells by blocking endolysosomal/melanosomal TPC2. In: Scientific reports, Bd. 11, Nr. 1, 8515 [PDF, 4MB]

Alexander, Stephen P. H.; Mathie, Alistair; Peters, John A.; Veale, Emma L.; Striessnig, Jorg; Kelly, Eamonn; Armstrong, Jane F.; Faccenda, Elena; Harding, Simon D.; Pawson, Adam J.; Southan, Christopher; Davies, Jamie A.; Aldrich, Richard W.; Attali, Bernard; Baggetta, Austin M.; Becirovic, Elvir; Biel, Martin; Bill, Roslyn M.; Catterall, William A.; Conner, Alex C.; Davies, Paul; Delling, Markus; Di Virgilio, Francesco; Falzoni, Simonetta; Fenske, Stefanie; George, Chandy; Goldstein, Steve A. N.; Grissmer, Stephan; Ha, Kotdaji; Hammelmann, Verena; Hanukoglu, Israel; Jarvis, Mike; Jensen, AndersA; Kaczmarek, Leonard K.; Kellenberger, Stephan; Kennedy, Charles; King, Brian; Kitchen, Philip; Lynch, Joseph W.; Perez-Reyes, Edward; Plant, Leigh D.; Rash, Lachlan; Ren, Dejian; Salman, Mootaz M.; Sivilotti, Lucia G.; Smart, Trevor G.; Snutch, Terrance P.; Tian, Jinbin; Trimmer, James S.; Eynde, Charlotte van den; Vriens, Joris; Wei, Aguan D.; Winn, Brenda T.; Wulff, Heike; Xu, Haoxing; Yue, Lixia; Zhang, Xiaoli und Zhu, Michael (2021): THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels. In: British Journal of Pharmacology, Bd. 178: S157-S245

Hennis, Konstantin; Biel, Martin; Wahl-Schott, Christian und Fenske, Stefanie (2021): Beyond pacemaking: HCN channels in sinoatrial node function. In: Progress in Biophysics & Molecular Biology, Bd. 166: S. 51-60

Koch, Mirja; Scheel, Constanze; Ma, Hongwei; Yang, Fan; Stadlmeier, Michael; Glück, Andrea F.; Murenu, Elisa; Traube, Franziska R.; Carell, Thomas; Biel, Martin; Ding, Xi-Qin und Michalakis, Stylianos (2021): The cGMP-Dependent Protein Kinase 2 Contributes to Cone Photoreceptor Degeneration in the Cnga3-Deficient Mouse Model of Achromatopsia. In: International Journal of Molecular Sciences, Bd. 22, Nr. 1, 52

Li, Yanfen; Schoen, Christian; Chen, Cheng-Chang; Yang, Zhuo; Liegl, Raffael; Murenu, Elisa; Schworm, Benedikt; Klugbauer, Norbert; Grimm, Christian; Wahl-Schott, Christian; Michalakis, Stylianos und Biel, Martin (2021): TPC2 promotes choroidal angiogenesis and inflammation in a mouse model of neovascular age-related macular degeneration. In: Life Science Alliance, Bd. 4, Nr. 8, e202101047

Müller, Martin; Gerndt, Susanne; Chao, Yu-Kai; Zisis, Themistoklis; Ong, Nam Phuong Nguyen; Gerwien, Aaron; Urban, Nicole; Müller, Christoph; Gegenfurtner, Florian A.; Geisslinger, Franz; Ortler, Carina; Chen, Cheng-Chang; Zahler, Stefan; Biel, Martin; Schäfer, Michael; Grimm, Christian; Bracher, Franz; Vollmar, Angelika M. und Bartel, Karin (2021): Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth. In: Cell Chemical Biology, Bd. 28, Nr. 8: 1119-

Pavlou, Marina; Schön, Christian; Occelli, Laurence M.; Rossi, Axel; Meumann, Nadja; Boyd, Ryan F.; Bartoe, Joshua T.; Siedlecki, Jakob; Gerhardt, Maximilian J.; Babutzka, Sabrina; Bogedein, Jacqueline; Wagner, Johanna E.; Priglinger, Siegfried G.; Biel, Martin; Petersen-Jones, Simon M.; Büning, Hildegard und Michalakis, Stylianos (2021): Novel AAV capsids for intravitreal gene therapy of photoreceptor disorders. In: EMBO Molecular Medicine, Bd. 13, Nr. 4, e13392 [PDF, 4MB]

Rieser, Ruth; Koch, Johanna; Faccioli, Greta; Richter, Klaus; Menzen, Tim; Biel, Martin; Winter, Gerhard und Michalakis, Stylianos (2021): Comparison of Different Liquid Chromatography-Based Purification Strategies for Adeno-Associated Virus Vectors. In: Pharmaceutics, Bd. 13, Nr. 5, 748

Rotzer, Rene D.; Brox, Verena F.; Hennis, Konstantin; Thalhammer, Stefan B.; Biel, Martin; Wahl-Schott, Christian und Fenske, Stefanie (2021): Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice. In: Jove-Journal of Visualized Experiments, Nr. 168, e62101

Traube, Franziska R.; Ozdemir, Dilara; Sahin, Hanife; Scheel, Constanze; Glück, Andrea F.; Geserich, Anna S.; Oganesian, Sabine; Kostidis, Sarantos; Iwan, Katharina; Rahimoff, Rene; Giorgio, Grazia; Mueller, Markus; Spada, Fabio; Biel, Martin; Cox, Juergen; Giera, Martin; Michalakis, Stylianos und Carell, Thomas (2021): Redirected nuclear glutamate dehydrogenase supplies Tet3 with alpha-ketoglutarate in neurons. In: Nature Communications, Bd. 12, Nr. 1, 4100

Reichel, Felix Friedrich ORCID logoORCID: https://orcid.org/0000-0001-9325-5616; Michalakis, Stylianos ORCID logoORCID: https://orcid.org/0000-0001-5092-9238; Wilhelm, Barbara; Zobor, Ditta; Muehlfriedel, Regine; Kohl, Susanne; Weisschuh, Nicole; Sothilingam, Vithiyanjali; Kuehlewein, Laura ORCID logoORCID: https://orcid.org/0000-0003-1906-8681; Kahle, Nadine; Seitz, Immanuel ORCID logoORCID: https://orcid.org/0000-0002-3086-6425; Paquet-Durand, Francois ORCID logoORCID: https://orcid.org/0000-0001-7355-5742; Tsang, Stephen H.; Martus, Peter; Peters, Tobias; Seeliger, Mathias; Bartz-Schmidt, Karl Ulrich; Ueffing, Marius; Zrenner, Eberhard; Biel, Martin; Wissinger, Bernd und Fischer, Dominik (2021): Three-year results of phase I retinal gene therapy trial for CNGA3-mutated achromatopsia: results of a non randomised controlled trial. In: British Journal of Ophthalmology, Bd. 106, Nr. 11: S. 1567-1572

2020

Fischer, M. Dominik; Michalakis, Stylianos; Wilhelm, Barbara; Zobor, Ditta; Muehlfriedel, Regine; Kohl, Susanne; Weisschuh, Nicole; Ochakovski, G. Alex; Klein, Reinhild; Schoen, Christian; Sothilingam, Vithiyanjali; Garcia-Garrido, Marina; Kuehlewein, Laura; Kahle, Nadine; Werner, Annette; Dauletbekov, Daniyar; Paquet-Durand, Francois; Tsang, Stephen; Martus, Peter; Peters, Tobias; Seeliger, Mathias; Bartz-Schmidt, Karl Ulrich; Ueffing, Marius; Zrenner, Eberhart; Biel, Martin und Wissinger, Bernd (2020): Safety and Vision Outcomes of Subretinal Gene Therapy Targeting Cone Photoreceptors in Achromatopsia A Nonrandomized Controlled Trial. In: Jama Ophthalmology, Bd. 138, Nr. 6: S. 643-651

Rieser, Ruth; Penaud-Budloo, Magalie; Bouzelha, Mohammed; Rossi, Axel; Menzen, Tim; Biel, Martin; Buening, Hildegard; Ayuso, Eduard; Winter, Gerhard und Michalakis, Stylianos (2020): Intrinsic Differential Scanning Fluorimetry for Fast and Easy Identification of Adeno-Associated Virus Serotypes. In: Journal of Pharmaceutical Sciences, Bd. 109, Nr. 1: S. 854-862

Arlt, Elisabeth; Fraticelli, Marco; Tsvilovskyy, Volodymyr; Nadolni, Wiebke; Breit, Andreas; O'Neill, Thomas J.; Resenberger, Stefanie; Wennemuth, Gunther; Wahl-Schott, Christian; Biel, Martin; Grimm, Christian; Freichel, Marc; Gudermann, Thomas; Klugbauer, Norbert; Boekhoff, Ingrid und Zierler, Susanna (2020): TPC1 deficiency or blockade augments systemic anaphylaxis and mast cell activity. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 117, Nr. 30: S. 18068-18078

Chen, Cheng-Chang; Krogsaeter, Einar; Butz, Elisabeth S.; Li, Yanfen; Puertollano, Rosa; Wahl-Schott, Christian; Biel, Martin und Grimm, Christian (2020): TRPML2 is an osmo/mechanosensitive cation channel in endolysosomal organelles. In: Science Advances, Bd. 6, Nr. 46, eabb5064

Gerndt, Susanne; Chen, Cheng-Chang; Chao, Yu-Kai; Yuan, Yu; Burgstaller, Sandra; Rosato, Anna Scotto; Krogsaeter, Einar; Urban, Nicole; Jacob, Katharina; Ong, Nam Phuong Nguyen; Miller, Meghan T.; Keller, Marco; Vollmar, Angelika M.; Gudermann, Thomas; Zierler, Susanna; Schredelseker, Johann; Schaefer, Michael; Biel, Martin; Malli, Roland; Wahl-Schott, Christian; Bracher, Franz; Patel, Sandip und Grimm, Christian (2020): Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function. In: eLife, Bd. 9, e54712 [PDF, 4MB]

Boehm, Sybille; Splith, Victoria; Riedmayr, Lisa Maria; Rotzer, Rene Dominik; Gasparoni, Gilles; Nordstroem, Karl J. V.; Wagner, Johanna Elisabeth; Hinrichsmeyer, Klara Sonnie; Walter, Joern; Wahl-Schott, Christian; Fenske, Stefanie; Biel, Martin; Michalakis, Stylianos und Becirovic, Elvir (2020): A gene therapy for inherited blindness using dCas9-VPR-mediated transcriptional activation. In: Science Advances, Bd. 6, Nr. 34, eaba5614

Panagiotopoulos, Anna-Lena; Karguth, Nina; Pavlou, Marina; Boehm, Sybille; Gasparoni, Gilles; Walter, Joern; Graf, Alexander; Blum, Helmut; Biel, Martin; Riedmayr, Lisa Maria und Becirovic, Elvir (2020): Antisense Oligonucleotide- and CRISPR-Cas9-Mediated Rescue of mRNA Splicing for a Deep Intronic CLRN1 Mutation. In: Molecular Therapy-Nucleic Acids, Bd. 21: S. 1050-1061

Fenske, Stefanie; Hennis, Konstantin; Roetzer, Rene D.; Brox, Verena F.; Becirovic, Elvir; Scharr, Andreas; Gruner, Christian; Ziegler, Tilman; Mehlfeld, Verena; Brennan, Jaclyn; Efimov, Igor R.; Pauza, Audrys G.; Moser, Markus; Wotjak, Carsten T.; Kupatt, Christian; Goenner, Rasmus; Zhang, Rai; Zhang, Henggui; Zong, Xiangang; Biel, Martin und Wahl-Schott, Christian (2020): cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells. In: Nature Communications, Bd. 11, Nr. 1, 5555 [PDF, 10MB]

Riedmayr, Lisa M.; Boehm, Sybille; Biel, Martin und Becirovic, Elvir (2020): Enigmatic rhodopsin mutation creates an exceptionally strong splice acceptor site. In: Human Molecular Genetics, Bd. 29, Nr. 2: S. 295-304

Kallenborn-Gerhardt, Wiebke; Metzner, Katharina; Lu, Ruirui; Petersen, Jonas; Kuth, Miriam S.; Heine, Sandra; Drees, Oliver; Paul, Mandy; Becirovic, Elvir; Kennel, Lea; Flauaus, Cathrin; Gross, Tilman; Wack, Gesine; Hohmann, Stephan W.; Nemirovski, Dina; Del Turco, Domenico; Biel, Martin; Geisslinger, Gerd; Michalakis, Stylianos und Schmidtko, Achim (2020): Neuropathic and cAMP-induced pain behavior is ameliorated in mice lacking CNGB1. In: Neuropharmacology, Bd. 171, 108087

2019

Krogsaeter, Einar K.; Biel, Martin; Wahl-Schott, Christian und Grimm, Christian (2019): The protein interaction networks of mucolipins and two-pore channels. In: Biochimica et Biophysica Acta-Molecular Cell Research, Bd. 1866, Nr. 7: S. 1111-1123

Lainez, Sergio; Tsantoulas, Christoforos; Biel, Martin und McNaughton, Peter A. (2019): HCN3 ion channels: roles in sensory neuronal excitability and pain. In: Journal of Physiology-London, Bd. 597, Nr. 17: S. 4661-4675

Tobias, Peters; Philipp, Seitz Immanuel; Stylianos, Michalakis; Martin, Biel; Barbara, Wilhelm; Felix, Reichel; Alexander, Ochakovski Guy; Eberhart, Zrenner; Marius, Ueffing; Birgit, Korbmacher; Sven, Korte; Ulrich, Bartz-Schmidt Karl; Dominik, Fischer Manuel; Bartz-Schmidt, Karl Ulrich; Bolz, Sylvia; Fischer, Dominik; Kohl, Susanne; Kuehlewein, Laura; Muehlfriedel, Regine; Neubauer, Jonas; Ochakovski, Alex; Paquet-Durand, Francois; Seeliger, Mathias; Sothilingam, Vithiyanjali; Ueffing, Marius; Weisschuh, Nicole; Wissinger, Bernd; Zhour, Ahmad; Zobor, Ditta; Zrenner, Eberhart; Biel, Martin; Michalakis, Stylianos; Schön, Christian; Kahle, Nadine; Peters, Tobias; Wilhelm, Barbara; Tsang, Steven und Gloeckner, Christian Johannes (2019): Safety and Toxicology of Ocular Gene Therapy with Recombinant AAV Vector rAAV.hCNGA3 in Nonhuman Primates. In: Human Gene Therapy Clinical Development, Bd. 30, Nr. 2: S. 50-56

Hammelmann, Verena; Stieglitz, Marc Sebastian; Huelle, Henrik; Le Meur, Karim; Kass, Jennifer; Bruemmer, Manuela; Gruner, Christian; Roetzer, Rene Dominik; Fenske, Stefanie; Hartmann, Jana; Zott, Benedikt; Luthi, Anita; Spahn, Saskia; Moser, Markus; Isbrandt, Dirk; Ludwig, Andreas; Konnerth, Arthur; Wahl-Schott, Christian und Biel, Martin (2019): Abolishing cAMP sensitivity in HCN2 pacemaker channels induces generalized seizures. In: Jci Insight, Bd. 4, Nr. 9, e126418

Petersen-Jones, Simon M.; Occelli, Laurence M.; Biel, Martin und Michalakis, Stylianos (2019): Advancing Gene Therapy for PDE6A Retinitis Pigmentosa. In: Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, Bd. 1185: S. 103-107

2018

Burkard, Markus; Kohl, Susanne; Kratzig, Timm; Tanimoto, Naoyuki; Brennenstuhl, Christina; Bausch, Anne E.; Junger, Katrin; Reuter, Peggy; Sothilingam, Vithiyanjali; Beck, Susanne C.; Huber, Gesine; Ding, Xi-Qin; Mayer, Anja K.; Baumann, Britta; Weisschuh, Nicole; Zobor, Ditta; Hahn, Gesa-Astrid; Kellner, Ulrich; Venturelli, Sascha; Becirovic, Elvir; Charbel Issa, Peter; Koenekoop, Robert K.; Rudolph, Gunther; Heckenlively, John; Sieving, Paul; Weleber, Richard G.; Hamel, Christian; Zong, Xiangang; Biel, Martin; Lukowski, Robert; Seeliger, Matthias W.; Michalakis, Stylianos; Wissinger, Bernd und Ruth, Peter (2018): Accessory heterozygous mutations in cone photoreceptor CNGA3 exacerbate CNG channel-associated retinopathy. In: The Journal of Clinical Investigation, Bd. 128, Nr. 12: S. 5663-5675

Keplinger, Stefan; Beiderbeck, Barbara; Michalakis, Stylianos; Biel, Martin; Grothe, Benedikt ORCID logoORCID: https://orcid.org/0000-0001-7317-0615 und Kunz, Lars ORCID logoORCID: https://orcid.org/0000-0003-3141-0005 (2018): Optogenetic Control of Neural Circuits in the Mongolian Gerbil. In: Frontiers in Cellular Neuroscience, Bd. 12, 111 [PDF, 2MB]

Plesch, Eva; Chen, Cheng-Chang; Butz, Elisabeth; Rosato, Anna Scotto; Krogsaeter, Einar K.; Yinan, Hua; Bartel, Karin; Keller, Marco; Robaa, Dina; Teupser, Daniel; Holdt, Lesca M.; Vollmar, Angelika M.; Sippl, Wolfgang; Puertollano, Rosa; Medina, Diego; Biel, Martin; Wahl-Schott, Christian; Bracher, Franz und Grimm, Christian (2018): Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells. In: eLife, Bd. 7, e39720 [PDF, 4MB]

Stieglitz, Marc S.; Fenske, Stefanie; Hammelmann, Verena; Becirovic, Elvir; Schöttle, Verena; Delorme, James E.; Schöll-Weidinger, Martha; Mader, Robert; Deussing, Jan; Wolfer, David P.; Seeliger, Mathias W.; Albrecht, Urs; Wotjak, Carsten T.; Biel, Martin; Michalakis, Stylianos und Wahl-Schott, Christian (2018): Disturbed Processing of Contextual Information in HCN3 Channel Deficient Mice. In: Frontiers in Molecular Neuroscience, Bd. 10, 436 [PDF, 4MB]

Blank, Thomas; Goldmann, Tobias; Koch, Mirja; Amann, Lukas; Schön, Christian; Bonin, Michael; Pang, Shengru; Prinz, Marco; Burnet, Michael; Wagner, Johanna E.; Biel, Martin und Michalakis, Stylianos (2018): Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa. In: Frontiers in Immunology, Bd. 8, 1930 [PDF, 7MB]

Kahle, Nadine A.; Peters, Tobias; Zobor, Ditta; Kuehlewein, Laura; Kohl, Susanne; Zhour, Ahmad; Werner, Annette; Seitz, Immanuel P.; Sothilingam, Vithiyanjali; Michalakis, Stylianos; Biel, Martin; Ueffing, Marius; Zrenner, Eberhart; Bartz-Schmidt, Karl U.; Fischer, M. Dominik und Wilhelm, Barbara J. C. (2018): Development of Methodology and Study Protocol: Safety and Efficacy of a Single Subretinal Injection of rAAV.hCNGA3 in Patients with CNGA3-Linked Achromatopsia Investigated in an Exploratory Dose-Escalation Trial. In: Human Gene Therapy Clinical Development, Bd. 29, Nr. 3: S. 121-131

Grimm, Christian; Bartel, Karin; Vollmar, Angelika M. und Biel, Martin (2018): Endolysosomal Cation Channels and Cancer-A Link with Great Potential. In: Pharmaceuticals, Bd. 11, Nr. 1 [PDF, 782kB]

Reichel, Felix F.; Peters, Tobias; Wilhelm, Barbara; Biel, Martin; Ueffing, Marius; Wissinger, Bernd; Bartz-Schmidt, Karl U.; Klein, Reinhild; Michalakis, Stylianos und Fischer, M. Dominik (2018): Humoral Immune Response After Intravitreal But Not After Subretinal AAV8 in Primates and Patients. In: Investigative Ophthalmology & Visual Science, Bd. 59, Nr. 5: S. 1910-1915 [PDF, 559kB]

Michalakis, Stylianos; Becirovic, Elvir und Biel, Martin (2018): Retinal Cyclic Nucleotide-Gated Channels: From Pathophysiology to Therapy. In: International Journal of Molecular Sciences, Bd. 19, Nr. 3, 749 [PDF, 2MB]

Barben, Maya; Ail, Divya; Storti, Federica; Klee, Katrin; Schori, Christian; Samardzija, Marijana; Michalakis, Stylianos; Biel, Martin; Meneau, Isabelle; Blaser, Frank; Barthelmes, Daniel und Grimm, Christian (2018): Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress. In: Cell Death and Differentiation, Bd. 25, Nr. 12: S. 2071-2085 [PDF, 6MB]

2017

Grimm, Christian; Chen, Cheng-Chang; Wahl-Schott, Christian und Biel, Martin (Februar 2017): Two-Pore Channels: Catalyzers of Endolysosomal Transport and Function. In: Frontiers in Pharmacology, Bd. 8, 45 [PDF, 662kB]

Chao, Yu-Kai; Schludi, Verena; Chen, Cheng-Chang; Butz, Elisabeth; Nguyen, O. N. Phuong; Müller, Martin; Krüger, Jens; Kammerbauer, Claudia; Ben-Johny, Manu; Vollmar, Angelika M.; Berking, Carola; Biel, Martin; Wahl-Schott, Christian A. und Grimm, Christian (2017): TPC2 polymorphisms associated with a hair pigmentation phenotype in humans result in gain of channel function by independent mechanisms. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 114, Nr. 41, E8595-E8602

Laprell, Laura; Tochitsky, Ivan; Kaur, Kuldeep; Manookin, Michael B.; Stein, Marco; Barber, David M.; Schön, Christian; Michalakis, Stylianos; Biel, Martin; Kramer, Richard H.; Sumser, Martin P.; Trauner, Dirk und Gelder, Russell N. van (2017): Photopharmacological control of bipolar cells restores visual function in blind mice. In: Journal of Clinical investigation, Bd. 127, Nr. 7: S. 2598-2611

Reichel, Felix F.; Dauletbekov, Daniyar L.; Klein, Reinhild; Peters, Tobias; Ochakoyski, G. Alex; Seitz, Immanuel P.; Wilhelm, Barbara; Üffing, Marius; Biel, Martin; Wissinger, Bernd; Michalakis, Stylianos; Bartz-Schmidt, Karl Ulrich und Fischer, M. Dominik (2017): AAV8 Can Induce Innate and Adaptive Immune Response in the Primate Eye. In: Molecular therapy, Bd. 25, Nr. 12: S. 2648-2660

Schön, Christian; Sothilingam, Vithiyanjali; Mühlfriedel, Regine; Garrido, Marina Garcia; Beck, Susanne C.; Tanimoto, Naoyuki; Wissinger, Bernd; Paquet-Durand, Francois; Biel, Martin; Michalakis, Stylianos und Seeliger, Mathias W. (2017): Gene Therapy Successfully Delays Degeneration in a Mouse Model of PDE6A-Linked Retinitis Pigmentosa (RP43). In: Human Gene therapy, Bd. 28, Nr. 12: S. 1180-1188

Occelli, Laurence M.; Schön, Christian; Seeliger, Mathias W.; Biel, Martin; Michalakis, Stylianos und Petersen-Jones, Simon M. (2017): Gene Supplementation Rescues Rod Function and Preserves Photoreceptor and Retinal Morphology in Dogs, Leading the Way Toward Treating Human PDE6A-Retinitis Pigmentosa. In: Human Gene therapy, Bd. 28, Nr. 12: S. 1189-1201

Grimm, Christian; Butz, Elisabeth; Chen, Cheng-Chang; Wahl-Schott, Christian und Biel, Martin (2017): From mucolipidosis type IV to Ebola: TRPML and two-pore channels at the crossroads of endo-lysosomal trafficking and disease. In: Cell Calcium, Bd. 67: S. 148-155

Herrmann, Stefan; Rajab, Hamsa; Christ, Irina; Schirdewahn, Christoph; Höfler, Daniel; Fischer, Michael J. M.; Bruno, Ariane; Fenske, Stefanie; Gruner, Christian; Kramer, Felix; Wachsmann, Tassilo; Wahl-Schott, Christian; Stieber, Juliane; Biel, Martin und Ludwig, Andreas (2017): Protein kinase A regulates inflammatory pain sensitization by modulating HCN2 channel activity in nociceptive sensory neurons. In: Pain, Bd. 158, Nr. 10: S. 2012-2024

Castonguay, Jan; Orth, Joachim H. C.; Müller, Thomas; Sleman, Faten; Grimm, Christian; Wahl-Schott, Christian; Biel, Martin; Mallmann, Robert Theodor; Bildl, Wolfgang; Schulte, Uwe und Klugbauer, Norbert (2017): The two-pore channel TPC1 is required for efficient protein processing through early and recycling endosomes. In: Scientific Reports, Bd. 7, 10038 [PDF, 4MB]

Chen, Cheng-Chang; Cang, Chunlei; Fenske, Stefanie; Butz, Elisabeth; Chao, Yu-Kai; Biel, Martin; Ren, Dejian; Wahl-Schott, Christian und Grimm, Christian (2017): Patch-clamp technique to characterize ion channels in enlarged individual endolysosomes. In: Nature Protocols, Bd. 12, Nr. 8: S. 1639-1658

Chen, Cheng-Chang; Butz, Elisabeth S.; Chao, Yu-Kai; Grishchuk, Yulia; Becker, Lars; Heller, Stefan; Slaugenhaupt, Susan A.; Biel, Martin; Wahl-Schott, Christian und Grimm, Christian (2017): Small Molecules for Early Endosome-Specific Patch Clamping. In: Cell Chemical Biology, Bd. 24, Nr. 7: S. 907-916

Butler, Michael R.; Ma, Hongwei; Yang, Fan; Belcher, Joshua; Le, Yun-Zheng; Mikoshiba, Katsuhiko; Biel, Martin; Michalakis, Stylianos; Iuso, Anthony; Krizaj, David und Ding, Xi-Qin (2017): Endoplasmic reticulum (ER) Ca2+-channel activity contributes to ER stress and cone death in cyclic nucleotide-gated channel deficiency. In: Journal of Biological Chemistry, Bd. 292, Nr. 27: S. 11189-11205

Böhm, Sybille; Riedmayr, Lisa M.; Nguyen, O. N. Phuong; Giessl, Andreas; Liebscher, Toni; Butz, Elisabeth S.; Schön, Christian; Michalakis, Stylianos; Wahl-Schott, Christian; Biel, Martin und Becirovic, Elvir (2017): Peripherin-2 and Rom-1 have opposing effects on rod outer segment targeting of retinitis pigmentosa-linked peripherin-2 mutants. In: Scientific Reports, Bd. 7, 2321 [PDF, 3MB]

Michalakis, Stylianos; Fischer, M. Dominik; Schön, Christian; Wilhelm, Barbara; Zobor, Ditta; Muhlfriedel, Regine; Sothilingam, Vithiyanjali; Kohl, Susanne; Peters, Tobias; Zrenner, Eberhart; Bartz-Schmidt, Karl Ulrich; Üffing, Marius; Wissinger, Bernd; Seeliger, Mathias und Biel, Martin (2017): Gene Supplementation Therapy for CNGA3-Linked Achromatopsia. In: Molecular therapy, Bd. 25, Nr. 5: S. 354

Nguyen, Ong Nam Phuong; Grimm, Christian; Schneider, Lina S.; Chao, Yu-Kai; Atzberger, Carina; Bartel, Karin; Watermann, Anna; Ulrich, Melanie; Mayr, Doris; Wahl-Schott, Christian; Biel, Martin und Vollmar, Angelika M. (2017): Two-Pore Channel Function Is Crucial for the Migration of Invasive Cancer Cells. In: Cancer Research, Bd. 77, Nr. 6: S. 1427-1438

Mühlfriedel, Regine; Tanimoto, Naoyuki; Schön, Christian; Sothilingam, Vithiyanjali; Garrido, Marina Garcia; Beck, Susanne C.; Huber, Gesine; Biel, Martin; Seeliger, Mathias W. und Michalakis, Stylianos (2017): AAV-Mediated Gene Supplementation Therapy in Achromatopsia Type 2: Preclinical Data on Therapeutic Time Window and Long-Term Effects. In: Frontiers in Neuroscience, Bd. 11, 292 [PDF, 5MB]

Bobak, Nicole; Feliciangeli, Sylvain; Chen, Cheng-Chang; Ben Soussia, Ismail; Bittner, Stefan; Pagnotta, Sophie; Ruck, Tobias; Biel, Martin; Wahl-Schott, Christian; Grimm, Christian; Meuth, Sven G. und Lesage, Florian (2017): Recombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels. In: Scientific Reports, Bd. 7, 649 [PDF, 11MB]

Michalakis, Stylianos; Shaltiel, Lior; Sothilingam, Vithiyanjali; Koch, Susanne; Schludi, Verena; Krause, Stefanie; Zeitz, Christina; Audo, Isabelle; Lancelot, Marie-Elise; Hamel, Christian; Meunier, Isabelle; Preising, Markus N.; Friedburg, Christoph; Lorenz, Birgit; Zabouri, Nawal; Haverkamp, Silke; Garcia Garrido, Marina; Tanimoto, Naoyuki; Seeliger, Mathias W.; Biel, Martin und Wahl-Schott, Christian A. (2017): Mosaic synaptopathy and functional defects in Cav1.4 heterozygous mice and human carriers of CSNB2 (vol 23, pg 1538, 2014). In: Human Molecular Genetics, Bd. 26, Nr. 2: S. 466

Michalakis, Stylianos; Schön, Christian; Becirovic, Elvir und Biel, Martin (2017): Gene therapy for achromatopsia. In: Journal of Gene Medicine, Bd. 19, Nr. 3, e2944

2016

Becirovic, Elvir; Böhm, Sybille; Nguyen, Ong N. P.; Riedmayr, Lisa M.; Hammelmann, Verena; Schön, Christian; Butz, Elisabeth S.; Wahl-Schott, Christian; Biel, Martin und Michalakis, Stylianos (2016): AAV Vectors for FRET-Based Analysis of Protein-Protein Interactions in Photoreceptor Outer Segments. In: Frontiers in Neuroscience, Bd. 10, 356 [PDF, 3MB]

Sothilingam, Vithiyanjali; Michalakis, Stylianos; Garrido, Marina Garcia; Biel, Martin; Tanimoto, Naoyuki und Seeliger, Mathias W. (2016): HCN1 Channels Enhance Rod System Responsivity in the Retina under Conditions of Light Exposure.
In: PLOS ONE 11(1), e0147728 [PDF, 1MB]

Auffenberg, Eva; Jurik, Angela; Mattusch, Corinna; Stoffel, Rainer; Genewsky, Andreas; Namendorf, Christian; Schmid, Roland M.; Rammes, Gerhard; Biel, Martin; Uhr, Manfred; Moosmang, Sven; Michalakis, Stylianos; Wotjak, Carsten T. und Thoeringer, Christoph K. (2016): Remote and reversible inhibition of neurons and circuits by small molecule induced potassium channel stabilization. In: Scientific Reports, Bd. 6, 19293 [PDF, 977kB]

Becirovic, Elvir; Boehm, Sybille; Nguyen, Ong Nam Phuong; Riedmayr, Lisa Maria; Schroeder, Nadja; Giessl, Andreas; Michalakis, Stylianos und Biel, Martin (2016): Differential rescue of protein expression and localization of two adRP-linked PRPH2 mutants in rods is mediated by their specific binding characteristics. In: Investigative Ophthalmology & Visual Science, Bd. 57, Nr. 12

Belcher, Josh; Butler, Michael R.; Ma, Hongwei; Xu, Catherine; Biel, Martin; Michalakis, Stylianos; Iuso, Anthony; Krizaj, David und Ding, Xi-Qin (2016): Inhibition of Endoplasmic Reticulum Calcium Channels Reduces Endoplasmic Reticulum Stress and Cone Death in CNG Channel-Deficient Mice. In: Investigative Ophthalmology & Visual Science, Bd. 57, Nr. 12

Becirovic, Elvir; Böhm, Sybille; Nguyen, Ong Nam Phuong; Riedmayr, Lisa Maria; Koch, Mirja Annika; Schulze, Elisabeth; Kohl, Susanne; Borsch, Oliver; Santos-Ferreira, Tiago; Ader, Marius; Michalakis, Stylianos und Biel, Martin (2016): In Vivo Analysis of Disease-Associated Point Mutations Unveils Profound Differences in mRNA Splicing of Peripherin-2 in Rod and Cone Photoreceptors.
In: PLOS Genetics 12(1), e1005811 [PDF, 8MB]

Schön, Christian; Asteriti, Sabrina; Koch, Susanne; Sothilingam, Vithiyanjali; Garrido, Marina Garcia; Tanimoto, Naoyuki; Herms, Jochen; Seeliger, Mathias W.; Cangiano, Lorenzo; Biel, Martin und Michalakis, Stylianos (2016): Loss of HCN1 enhances disease progression in mouse models of CNG channel-linked retinitis pigmentosa and achromatopsia. In: Human Molecular Genetics, Bd. 25, Nr. 6: S. 1165-1175

Michalakis, Stylianos; Koch, Mirwa; Ma, Hongwei; Ding, Xi-Qin und Biel, Martin (2016): cGMP-cGKII signalling contributes to cone photoreceptor degeneration in achromatopsia. In: Investigative Ophthalmology & Visual Science, Bd. 57, Nr. 12

Reichel, Felix Friedrich; Peters, Tobias; Muehlfriedel, Regine; Biel, Martin; Paquet-Durand, Francois; Ueffing, Marius; Wissinger, Bernd; Bartz-Schmidt, Karl Ulrich; Fischer, M. Dominik und Michalakis, Stylianos (2016): Humoral immune response to subretinal AAV8 in non-human primates. In: Investigative Ophthalmology & Visual Science, Bd. 57, Nr. 12

Fischer, M. Dominik; Wilhelm, Barbara; Michalakis, Stylianos; Zobor, Ditta; Kohl, Susanne; Seeliger, Matthias; Zrenner, Eberhart; Ueffing, Marius; Wissinger, Bernd; Biel, Martin und Bartz-Schmidt, Karl Ulrich (2016): Successful delivery of rAAV8.CNGA3 in a patient with CNGA3 achromatopsia. In: Investigative Ophthalmology & Visual Science, Bd. 57, Nr. 12

Fenske, Stefanie; Pröbstle, Rasmus; Auer, Franziska; Hassan, Sami; Marks, Vanessa; Pauza, Danius H.; Biel, Martin und Wahl-Schott, Christian (2016): Comprehensive multilevel in vivo and in vitro analysis of heart rate fluctuations in mice by ECG telemetry and electrophysiology. In: Nature Protocols, Bd. 11, Nr. 1: S. 61-86

Nguyen, O. N. Phuong; Böhm, Sybille; Gießl, Andreas; Butz, Elisabeth S.; Wolfrum, Uwe; Brandstätter, Johann H.; Wahl-Schott, Christian; Biel, Martin und Becirovic, Elvir (2016): Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors. In: Human Molecular Genetics, Bd. 25, Nr. 12: S. 2367-2377

Kostic, Corinne; Crippa, Sylvain V.; Martin, Catherine; Kardon, Randy H.; Biel, Martin; Arsenijevic, Yvan und Kawasaki, Aki (2016): Determination of Rod and Cone Influence to the Early and Late Dynamic of the Pupillary Light Response. In: Investigative Ophthalmology & Visual Science, Bd. 57, Nr. 6: S. 2501-2508

Seitz, Immanuel Philipp; Fischer, M. Dominik; Michalakis, Stylianos; Wilhelm, Barbara; Kahle, Nadine; Zrenner, Eberhart; Ueffing, Marius; Bartz-Schmidt, Karl Ulrich; Biel, Martin; Wissinger, Bernd und Peters, Tobias (2016): rAAV8 biodistribution and shedding after subretinal injection in non-human primates. In: Investigative Ophthalmology & Visual Science, Bd. 57, Nr. 12

2015

Bender, Julia; Engeholm, Maik; Ederer, Marion S.; Breu, Johannes; Moller, Thor C.; Michalakis, Stylianos; Rasko, Tamas; Wanker, Erich E.; Biel, Martin; Martinez, Karen L.; Wurst, Wolfgang und Deussing, Jan M. (2015): Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif.
In: PLOS ONE 10(9), e0136768 [PDF, 20MB]

Tanimoto, Naoyuki; Sothilingam, Vithiyanjali; Kondo, Mineo; Biel, Martin; Humphries, Peter und Seeliger, Mathias W. (2015): Electroretinographic assessment of rod- and cone-mediated bipolar cell pathways using flicker stimuli in mice. In: Scientific Reports, Bd. 5, 10731 [PDF, 960kB]

Perera, Arshan; Eisen, David; Wagner, Mirko; Laube, Silvia K.; Künzel, Andrea F.; Koch, Susanne; Steinbacher, Jessica; Schulze, Elisabeth; Splith, Victoria; Mittermeier, Nana; Mueller, Markus; Biel, Martin; Carell, Thomas und Michalakis, Stylianos (2015): TET3 Is Recruited by REST for Context-Specific Hydroxymethylation and Induction of Gene Expression. In: Cell Reports, Bd. 11, Nr. 2: S. 283-294 [PDF, 3MB]

Mattusch, Corinna; Kratzer, Stephan; Buerge, Martina; Kreuzer, Matthias; Engel, Tatiana; Kopp, Claudia; Biel, Martin; Hammelmann, Verena; Ying, Shui-Wang; Goldstein, Peter A.; Kochs, Eberhard; Haseneder, Rainer und Rammes, Gerhard (2015): Impact of Hyperpolarization-activated, Cyclic Nucleotide-gated Cation Channel Type 2 for the Xenon-mediated Anesthetic Effect: Evidence from In Vitro and In Vivo Experiments. In: Anesthesiology, Bd. 122, Nr. 5: S. 1047-1059 [PDF, 804kB]

2014

Arango-Gonzalez, Blanca; Trifunović, Dragana; Sahaboglu, Ayse; Kranz, Katharina; Michalakis, Stylianos; Farinelli, Pietro; Koch, Susanne; Koch, Fred; Cottet, Sandra; Janssen-Bienhold, Ulrike; Dedek, Karin; Biel, Martin; Zrenner, Eberhart; Euler, Thomas; Ekstrom, Per; Ueffing, Marius und Paquet-Durand, François (2014): Identification of a Common Non-Apoptotic Cell Death Mechanism in Hereditary Retinal Degeneration.
In: PLOS ONE 9(11), e112142 [PDF, 1MB]

Chen, Cheng-Chang; Keller, Marco; Hess, Martin; Schiffmann, Raphael; Urban, Nicole; Wolfgardt, Annette; Schaefer, Michael; Bracher, Franz; Biel, Martin; Wahl-Schott, Christian und Grimm, Christian (2014): A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV. In: Nature Communications, Bd. 5, 4681 [PDF, 1MB]

Grimm, Christian; Holdt, Lesca M.; Chen, Cheng-Chang; Hassan, Sami; Müller, Christoph; Jörs, Simone; Cuny, Hartmut; Kissing, Sandra; Schröder, Bernd; Butz, Elisabeth; Northoff, Bernd; Castonguay, Jan; Luber, Christian A.; Moser, Markus; Spahn, Saskia; Luellmann-Rauch, Renate; Fendel, Christina; Klugbauer, Norbert; Griesbeck, Oliver; Haas, Albert; Mann, Matthias; Bracher, Franz; Teupser, Daniel; Saftig, Paul; Biel, Martin und Wahl-Schott, Christian (2014): High susceptibility to fatty liver disease in two-pore channel 2-deficient mice. In: Nature Communications, Bd. 5, 4699 [PDF, 3MB]

Soltysinska, Ewa; Bentzen, Bo Hjorth; Barthmes, Maria; Hattel, Helle; Thrush, A. Brianne; Harper, Mary-Ellen; Qvortrup, Klaus; Larsen, Filip J.; Schiffer, Tomas A.; Losa-Reyna, Jose; Straubinger, Julia; Kniess, Angelina; Thomsen, Morten Bækgaard; Brüggemann, Andrea; Fenske, Stefanie; Biel, Martin; Ruth, Peter; Wahl-Schott, Christian; Boushel, Robert Christopher; Olesen, Søren-Peter und Lukowski, Robert (2014): KCNMA1 Encoded Cardiac BK Channels Afford Protection against Ischemia-Reperfusion Injury.
In: PLOS ONE 9(7), e103402 [PDF, 1MB]

Neuner, Johanna; Ovsepian, Saak V.; Dorostkar, Mario; Filser, Severin; Gupta, Aayush; Michalakis, Stylianos; Biel, Martin und Herms, Jochen (2014): Pathological alpha-synuclein impairs adult-born granule cell development and functional integration in the olfactory bulb. In: Nature Communications, Bd. 5, 3915 [PDF, 2MB]

Neuner, Johanna; Filser, Severin; Michalakis, Stylianos; Biel, Martin und Herms, Jochen (2014): A30P alpha-Synuclein interferes with the stable integration of adult-born neurons into the olfactory network. In: Scientific Reports, Bd. 4, 3931 [PDF, 11MB]

2011

Hammelmann, Verena; Zong, Xiangang; Hofmann, Franz; Michalakis, Stylianos und Biel, Martin (2011): The cGMP-dependent protein kinase II Is an inhibitory modulator of the hyperpolarization-activated HCN2 channel.
In: PLOS ONE 6(2), e17078 [PDF, 3MB]

Mamasuew, Katharina; Hofmann, Nina; Kretzschmann, Verena; Biel, Martin; Yang, Ruey-Bing; Breer, Heinz und Fleischer, Joerg (2011): Chemo- and Thermosensory Responsiveness of Grueneberg Ganglion Neurons Relies on Cyclic Guanosine Monophosphate Signaling Elements. In: Neurosignals, Nr. 4: S. 198-209 [PDF, 2MB]

2010

Becirovic, Elvir; Nakova, Kostadinka; Hammelmann, Verena; Hennel, Roman; Biel, Martin und Michalakis, Stylianos (29. Januar 2010): The retinitis pigmentosa mutation c.3444+1G>A in CNGB1 results in skipping of exon 32.
In: PLOS ONE 5(1), e8969 [PDF, 173kB]

Globisch, Daniel; Münzel, Martin; Müller, Markus; Michalakis, Stylianos; Wagner, Mirko; Koch, Susanne; Brückl, Tobias; Biel, Martin und Carell, Thomas (2010): Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates.
In: PLOS ONE 5(12), e15367 [PDF, 3MB]

1994

Biel, Martin; Zong, Xiangang; Distler, Madeleine; Bosse, Eva; Klugbauer, Norbert; Murakami, Manabu; Flockerzi, Veit und Hofmann, Franz (1994): Another member of the cyclic nucleotide-gated channel family, expressed in testis, kidney, and heart. In: Proceedings of the National Academy of Science of the U S A, Bd. 91, Nr. 9: S. 3505-3509 [PDF, 1MB]

Singer-Lahat, Dafna; Lotan, Ilana; Biel, Martin; Flockerzi, Veit; Hofmann, Franz und Dascal, Nathan (1994): Cardiac calcium channels expressed in Xenopus oocytes are modulated by dephosphorylation but not by cAMP-dependent phosphorylation. In: Receptors and Channels, Bd. 2: S. 215-226 [PDF, 7MB]

Hofmann, Franz; Biel, Martin; Bosse, Eva; Flockerzi, Veit; Ruth, Peter und Welling, A. (1994): Functional expression of cardiac and smooth muscle calcium channels. In: Spooner, Peter M. (Hrsg.): Ion channels in the cardiovascular system. Function and dysfunction. Armonk, NY: Futura Publishing Company. [PDF, 2MB]

Distler, Madeleine; Biel, Martin; Flockerzi, Veit und Hofmann, Franz (1994): Expression of cyclic nucleotide-gated cation channels in non-sensory tissues and cells. In: Neuropharmacology, Bd. 33: S. 1275-1282 [PDF, 6MB]

Hofmann, Franz; Biel, Martin und Flockerzi, Veit (1994): Molecular basis for Ca2+ channel diversity. In: Annual Review of Neurosciences, Bd. 17: S. 399-418 [PDF, 2MB]

1993

Biel, Martin; Altenhofen, Wolfram; Hullin, Roger; Ludwig, Jost; Freichel, Marc; Flockerzi, Veit; Dascal, Nathan; Kaupp, U. Benjamin und Hofmann, Franz (1993): Primary structure and functional expression of a cyclic nucleotidegated channel from rabbit aorta. In: FEBS Letters, Bd. 329, Nr. 1 - 2: S. 134-138 [PDF, 633kB]

Hullin, Roger; Biel, Martin; Bosse, Eva; Welling, Andrea; Hofmann, Franz und Flockerzi, Veit (1993): Genetischer Polymorphismus spannungsaktivierter Calciumkanäle. In: Ganten, Detlef (Hrsg.): Zelluläre Mechanismen der Herz-Kreislaufregulation. Stuttgart u.a.: Schattauer. S. 23-37 [PDF, 2MB]

Hullin, Roger; Biel, Martin; Flockerzi, Veit und Hofmann, Franz (1993): Tissue-specific expression of calcium channels. In: Trends in Cardiovascular Medicine, Bd. 3, Nr. 2: S. 48-53 [PDF, 931kB]

Hofmann, Franz; Biel, Martin; Bosse, Eva; Hullin, Roger; Ruth, Peter; Welling, A. und Flockerzi, Veit (1993): High voltage activated Ca2+ channel. In: Dickey, Burton F. und Birnbaumer, Lutz (Hrsg.): GTPases in Biology II. Handbook of Experimental Pharmacology, Bd. 108. Berlin u.a.: Springer. S. 225-238 [PDF, 2MB]

1992

Singer-Lahat, Dafna; Gershon, Eli; Lotan, Ilana; Hullin, Roger; Biel, Martin; Flockerzi, Veit; Hofmann, Franz und Dascal, Nathan (1992): Modulation of cardiac Ca2+ channels in Xenopus oocytes by protein kinase C. In: FEBS Letters, Bd. 306, Nr. 2-3: S. 113-118 [PDF, 703kB]

Hullin, Roger; Singer-Lahat, Dafna; Freichel, Marc; Biel, Martin; Dascal, Nathan; Hofmann, Franz und Flockerzi, Veit (1992): Calcium channel beta subunit heterogeneity. functional expression of cloned cDNA from heart, aorta and brain. In: EMBO Journal, Bd. 11, Nr. 3: S. 885-890 [PDF, 1MB]

Hofmann, Franz; Biel, Martin; Hullin, Roger; Bosse, Eva und Flockerzi, Veit (1992): Tissue distribution and possible function of the subunits of the L-type calcium channels. In: Morad, Martin und Agus, Zalman (Hrsg.): Intracellular regulation of ion channels. Berlin u.a.: Springer. S. 89-97 [PDF, 853kB]

1991

Singer, D.; Biel, Martin; Lotan, I.; Flockerzi, V.; Hofmann, Franz und Dascal, Nathan (1991): The roles of the subunits in the function of the calcium channel. In: Science, Bd. 253: S. 1553-1557 [PDF, 1MB]

Biel, Martin; Hullin, Roger; Freundner, Stefanie; Singer, Dafna; Dascal, Nathan; Flockerzi, Veit und Hofmann, Franz (1991): Tissue-specific expression of high-voltage-activated dihydropyridine-sensitive L-type calcium channels. In: European Journal of Biochemistry, Bd. 200, Nr. 1: S. 81-88 [PDF, 804kB]

Flockerzi, Veit; Bosse, Eva; Biel, Martin; Hullin, Roger und Hofmann, Franz (1991): High voltage activated calcium channels. molecular composition and function. In: European Heart Journal, Bd. 12, Nr. Suppl.: S. 95-98 [PDF, 1MB]

1990

Bosser, E.; Regulla, S.; Biel, Martin; Ruth, Peter; Meyer, E.; Flockerzi, Veit und Hofmann, Franz (1990): The cDNA and deduced amino acid sequence of the γ subunit of the L-type calcium channel from rabbit skeletal muscle. In: FEBS Letters, Bd. 267, Nr. 1: S. 153-156 [PDF, 406kB]

Biel, Martin; Ruth, Peter; Bosse, Eva; Hullin, Roger; Stühmer, Walter; Flockerzi, Veit und Hofmann, Franz (1990): Primary structure and functional expression of a high voltage activated calcium channel from rabbit lung. In: FEBS Letters, Bd. 269, Nr. 2: S. 409-412 [PDF, 517kB]

1989

Ruth, Peter; Rohrkasten, A.; Biel, Martin; Bosser, E.; Regulla, S.; Meyer, H. E.; Flockerzi, Veit und Hofmann, Franz (1989): Primary structure of the beta subunit of the DHP-sensitive calcium channel from skeletal muscle. In: Science, Bd. 245: S. 1115-1118 [PDF, 1MB]

Ruth, Peter; Flockerzi, Veit; Biel, Martin und Hofmann, Franz (1989): The structure of the skeletal muscle calcium channel. Smith Kline & French Research Symposium on Ion Transport, Cambridge, Großbritannien, 12. - 14. April 1989. Keeling, David (Hrsg.): In: Ion Transport, London: Academic Press. S. 147-157 [PDF, 1MB]

Hofmann, Franz; Ruth, Peter; Schneider, T.; Felbel, J.; Regulla, S.; Biel, Martin; Nastainczyk, E. und Flockerzi, Veit (1989): The structure of the skeletal and nonskeletal muscle calcium channel. 40. Colloquium, Mosbach, 6. - 8. April 1989. Gehring, U. (Hrsg.): In: Molecular mechanisms of hormone action, Berlin u.a.: Springer. S. 132-138 [PDF, 1MB]

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