Anzahl der Publikationen: 247
2024
Bender, Martin ORCID: https://orcid.org/0000-0002-9590-4728; Panelli, Alessandro; Reichart, Bruno ORCID: https://orcid.org/0000-0003-2859-3664; Radan, Julia; Mokelke, Maren; Neumann, Elisabeth; Buttgereit, Ines; Michel, Sebastian; Bauer, Andreas; Fresch, Ann Kathrin; Mayr, Tanja; Werner, Fabian; Egerer, Stefanie; Bähr, Andrea ORCID: https://orcid.org/0000-0001-8075-8222; Kessler, Barbara; Klymiuk, Nikolai; Ayares, David; Wolf, Eckhard ORCID: https://orcid.org/0000-0002-0430-9510; Hagl, Christian; Brenner, Paolo; Längin, Matthias ORCID: https://orcid.org/0000-0003-0996-4941 und Abicht, Jan‐Michael ORCID: https://orcid.org/0000-0001-7361-1249
(2024):
Hemodynamics in pig‐to‐baboon heterotopic thoracic cardiac xenotransplantation: Recovery from perioperative cardiac xenograft dysfunction and impairment by cardiac overgrowth.
In: Xenotransplantation, Bd. 31, Nr. 1
[PDF, 2MB]
Pilz, Johanna ORCID: https://orcid.org/0009-0007-7266-1894; Gloddek, Nicol ORCID: https://orcid.org/0009-0001-2229-8034; Lindheimer, Felix ORCID: https://orcid.org/0009-0002-6904-2623; Lindner, Magdalena Julia; Puhr-Westerheide, Daniel ORCID: https://orcid.org/0000-0003-3669-5572; Ümütlü, Muzzafer; Cyran, Clemens ORCID: https://orcid.org/0000-0001-5630-6242; Seidensticker, Max ORCID: https://orcid.org/0000-0002-2481-5410; Lindner, Richard ORCID: https://orcid.org/0000-0003-1836-5377; Kraetzl, Martin ORCID: https://orcid.org/0000-0002-8449-177X; Renner, Simone ORCID: https://orcid.org/0000-0002-5866-4577; Merkus, Daphne ORCID: https://orcid.org/0000-0002-4852-831X; Teupser, Daniel ORCID: https://orcid.org/0000-0001-9843-0145; Bartenstein, Peter ORCID: https://orcid.org/0009-0005-0734-4994; Ziegler, Sibylle I. ORCID: https://orcid.org/0000-0002-5321-4817; Wolf, Eckhard ORCID: https://orcid.org/0000-0002-0430-9510 und Kemter, Elisabeth ORCID: https://orcid.org/0000-0001-7785-7502
(2024):
Functional maturation and longitudinal imaging of intraportal neonatal porcine islet grafts in genetically diabetic pigs.
In: American Journal of Transplantation, Bd. 24, Nr. 8: S. 1395-1405
[PDF, 2MB]
Lange, Andreas; Medugorac, Ivica ORCID: https://orcid.org/0000-0002-6891-3039; Ali, Asghar; Kessler, Barbara; Kurome, Mayuko; Zakhartchenko, Valeri; Hammer, Sabine E. ORCID: https://orcid.org/0000-0003-1475-3938; Hauser, Andreas ORCID: https://orcid.org/0000-0002-3997-7252; Denner, Joachim ORCID: https://orcid.org/0000-0003-3244-6085; Dobenecker, Britta; Wess, Gerhard; Tan, Paul L. J.; Garkavenko, Olga; Reichart, Bruno ORCID: https://orcid.org/0000-0003-2859-3664; Wolf, Eckhard ORCID: https://orcid.org/0000-0002-0430-9510 und Kemter, Elisabeth ORCID: https://orcid.org/0000-0001-7785-7502
(2024):
Genetic diversity, growth and heart function of Auckland Island pigs, a potential source for organ xenotransplantation.
In: Xenotransplantation, Bd. 31, Nr. 2
[PDF, 3MB]
Mokelke, Maren; Bender, Martin ORCID: https://orcid.org/0000-0002-9590-4728; Reichart, Bruno ORCID: https://orcid.org/0000-0003-2859-3664; Neumann, Elisabeth; Radan, Julia; Buttgereit, Ines; Ayares, David; Wolf, Eckhard ORCID: https://orcid.org/0000-0002-0430-9510; Brenner, Paolo; Abicht, Jan‐Michael ORCID: https://orcid.org/0000-0001-7361-1249 und Längin, Matthias ORCID: https://orcid.org/0000-0003-0996-4941
(2024):
Transthoracic echocardiography is a simple tool for size matching in cardiac xenotransplantation.
In: Xenotransplantation, Bd. 31, Nr. 3
[PDF, 1MB]
Bender, Martin ORCID: https://orcid.org/0000-0002-9590-4728; Reichart, Bruno ORCID: https://orcid.org/0000-0003-2859-3664; Figueiredo, Constanca; Burgmann, Jonathan M.; Leuschen, Maria; Wall, Felicia; Radan, Julia; Neumann, Elisabeth; Mokelke, Maren; Buttgereit, Ines; Michel, Sebastian; Ellgass, Reinhard; Egerer, Stefanie; Lange, Andreas; Baehr, Andrea; Kessler, Barbara; Kemter, Elisabeth; Klymiuk, Nikolai; Denner, Joachim ORCID: https://orcid.org/0000-0003-3244-6085; Godehardt, Antonia W. ORCID: https://orcid.org/0000-0001-8014-5530; Tönjes, Ralf R.; Hagl, Christian; Gebauer, Michaela; Binder, Uli; Skerra, Arne; Ayares, David; Wolf, Eckhard ORCID: https://orcid.org/0000-0002-0430-9510; Schmoeckel, Michael; Brenner, Paolo; Längin, Matthias ORCID: https://orcid.org/0000-0003-0996-4941 und Abicht, Jan‐Michael ORCID: https://orcid.org/0000-0001-7361-1249
(2024):
An Approach to Controlling Inflammation and Coagulation in Pig‐to‐Baboon Cardiac Xenotransplantation.
In: Xenotransplantation, Bd. 31, Nr. 4
[PDF, 610kB]
Grimus, Sarah; Sarangova, Victoria; Welzel, Petra B.; Ludwig, Barbara; Seissler, Jochen; Kemter, Elisabeth; Wolf, Eckhard ORCID: https://orcid.org/0000-0002-0430-9510 und Ali, Asghar
(2024):
Immunoprotection Strategies in β‐Cell Replacement Therapy: A Closer Look at Porcine Islet Xenotransplantation.
In: Advanced Science, Bd. 11, Nr. 31
[PDF, 7MB]
Bauer, Julia; Vlcek, Julia ORCID: https://orcid.org/0009-0005-4448-4056; Pauly, Valerie; Hesse, Nora; Xia, Ruibing; Mo, Li ORCID: https://orcid.org/0009-0000-6548-3099; Chivukula, Aparna Sharma ORCID: https://orcid.org/0000-0002-3386-1654; Villgrater, Hannes ORCID: https://orcid.org/0009-0005-6796-4482; Dressler, Marie; Hildebrand, Bianca; Wolf, Eckhard ORCID: https://orcid.org/0000-0002-0430-9510; Rizas, Konstantinos D. ORCID: https://orcid.org/0000-0002-5993-0339; Bauer, Axel ORCID: https://orcid.org/0000-0001-9201-8555; Kääb, Stefan ORCID: https://orcid.org/0000-0001-8824-3581; Tomsits, Philipp ORCID: https://orcid.org/0000-0002-5842-9083; Schüttler, Dominik ORCID: https://orcid.org/0000-0002-2546-5862 und Clauss, Sebastian ORCID: https://orcid.org/0000-0002-5675-6128
(2024):
Biomarker Periodic Repolarization Dynamics Indicates Enhanced Risk for Arrhythmias and Sudden Cardiac Death in Myocardial Infarction in Pigs.
In: Journal of the American Heart Association, Bd. 13, Nr. 9
[PDF, 12MB]
2023
Shashikadze, Bachuki ORCID: https://orcid.org/0000-0003-4558-0785; Franzmeier, Sophie ORCID: https://orcid.org/0000-0002-1265-6790; Hofmann, Isabel ORCID: https://orcid.org/0000-0003-4019-9619; Kraetzl, Martin ORCID: https://orcid.org/0000-0002-8449-177X; Flenkenthaler, Florian ORCID: https://orcid.org/0000-0003-2964-9236; Blutke, Andreas ORCID: https://orcid.org/0000-0001-7824-2681; Fröhlich, Thomas ORCID: https://orcid.org/0000-0002-4709-3211; Wolf, Eckhard ORCID: https://orcid.org/0000-0002-0430-9510 und Hinrichs, Arne ORCID: https://orcid.org/0000-0003-3022-5983
(2023):
Structural and proteomic repercussions of growth hormone receptor deficiency on the pituitary gland: Lessons from a translational pig model.
In: Journal of Neuroendocrinology
[PDF, 2MB]
2022
Gong, Siyuan; Tetti, Martina; Kemter, Elisabeth ORCID: https://orcid.org/0000-0001-7785-7502; Peitzsch, Mirko; Mulatero, Paolo ORCID: https://orcid.org/0000-0002-5480-1116; Bidlingmaier, Martin; Eisenhofer, Graeme; Wolf, Eckhard ORCID: https://orcid.org/0000-0002-0430-9510; Reincke, Martin ORCID: https://orcid.org/0000-0002-9817-9875 und Williams, Tracy Ann ORCID: https://orcid.org/0000-0002-2388-6444
(Dezember 2022):
TSPAN12 (Tetraspanin 12) Is a Novel Negative Regulator of Aldosterone Production in Adrenal Physiology and Aldosterone-Producing Adenomas.
In: Hypertension, Nr. 2: S. 440-450
[PDF, 2MB]
Wolf, Eckhard
(2022):
Announcement.
In: Xenotransplantation, Bd. 29, Nr. 4
[PDF, 99kB]
Bender, Martin; Längin, Matthias; Reichart, Bruno; Mokelke, Maren; Radan, Julia; Neumann, Elisabeth; Michel, Sebastian; Ellgass, Reinhard; Cowan, Peter J.; Wolf, Eckhard; Abicht, Jan-Michael und Brenner, Paolo
(2022):
Clinical cardiac xenotransplantation first in the clinical arena.
In: Xenotransplantation, Bd. 29, Nr. 1
[PDF, 481kB]
Bender, Martin; Längin, Matthias; Reichart, Bruno; Mokelke, Maren; Radan, Julia; Neumann, Elisabeth; Michel, Sebastian; Ellgass, Reinhard; Cowan, Peter J.; Wolf, Eckhard; Abicht, Jan-Michael und Brenner, Paolo
(2022):
Overcoming perioperative inflammation as a hurdle for successful preclinical orthotopic cardiac xenogeneic transplantations - particular in regard of the mandatory use of heart-lung machines.
In: Xenotransplantation, Bd. 29, Nr. 3
[PDF, 406kB]
Donandt, Tina; Hintze, Stefan; Krause, Sabine; Wolf, Eckhard; Schoser, Benedikt; Walter, Maggie C. und Meinke, Peter
(2022):
Isolation and Characterization of Primary DMD Pig Muscle Cells as an In Vitro Model for Preclinical Research on Duchenne Muscular Dystrophy.
In: Life-Basel, Bd. 12, Nr. 10
[PDF, 3MB]
Simmet, Kilian; Kurome, Mayuko; Zakhartchenko, Valeri; Reichenbach, Horst-Dieter; Springer, Claudia; Bahr, Andrea; Blum, Helmut; Philippou-Massier, Julia und Wolf, Eckhard
(2022):
OCT4/POU5F1 is indispensable for the lineage differentiation of the inner cell mass in bovine embryos.
In: Faseb Journal, Bd. 36, Nr. 6
[PDF, 1MB]
Kemter, Elisabeth ORCID: https://orcid.org/0000-0001-7785-7502; Citro, Antonio; Wolf‐van Buerck, Lelia; Qiu, Yi; Böttcher, Anika; Policardi, Martina; Pellegrini, Silvia; Valla, Libera; Alunni‐Fabbroni, Marianna; Kobolák, Julianna; Kessler, Barbara; Kurome, Mayuko; Zakhartchenko, Valeri; Dinnyes, Andras; Cyran, Clemens C.; Lickert, Heiko; Piemonti, Lorenzo; Seissler, Jochen und Wolf, Eckhard
(2022):
Transgenic pigs expressing near infrared fluorescent protein—A novel tool for noninvasive imaging of islet xenotransplants.
In: Xenotransplantation, Bd. 29, Nr. 1
[PDF, 1MB]
Stirm, Michael; Fonteyne, Lina Marie; Shashikadze, Bachuki; Stoeckl, Jan B.; Kurome, Mayuko; Kessler, Barbara; Zakhartchenko, Valeri; Kemter, Elisabeth; Blum, Helmut; Arnold, Georg J.; Matiasek, Kaspar; Wanke, Ruediger; Wurst, Wolfgang; Nagashima, Hiroshi; Knieling, Ferdinand; Walter, Maggie C.; Kupatt, Christian; Froehlich, Thomas; Klymiuk, Nikolai; Blutke, Andreas und Wolf, Eckhard
(2022):
Pig models for Duchenne muscular dystrophy-from disease mechanisms to validation of new diagnostic and therapeutic concepts.
In: Neuromuscular Disorders, Bd. 32, Nr. 7: S. 543-556
Kraiger, Markus; Klein-Rodewald, Tanja; Rathkolb, Birgit; Calzada-Wack, Julia; Sanz-Moreno, Adrian; Fuchs, Helmut; Wolf, Eckhard; Gailus-Durner, Valerie und Hrabe de Angelis, Martin
(2022):
Monitoring longitudinal disease progression in a novel murine Kit tumor model using high-field MRI.
In: Scientific Reports, Bd. 12, Nr. 1, 14608
Klein-Rodewald, Tanja; Micklich, Kateryna; Sanz-Moreno, Adrian; Tost, Monica; Calzada-Wack, Julia; Adler, Thure; Klaften, Matthias; Sabrautzki, Sibylle; Aigner, Bernhard; Kraiger, Markus; Gailus-Durner, Valerie; Fuchs, Helmut; Gruender, Albert; Pahl, Heike; Wolf, Eckhard; Hrabe de Angelis, Martin und Rathkolb, Birgit
(2022):
New C3H Kit(N824K/WT) cancer mouse model develops late-onset malignant mammary tumors with high penetrance.
In: Scientific Reports, Bd. 12, Nr. 1, 19793
[PDF, 3MB]
Milenkovic, Dusanka; Sanz-Moreno, Adrian; Calzada-Wack, Julia; Rathkolb, Birgit; Veronica Amarie, Oana; Gerlini, Raffaele; Aguilar-Pimentel, Antonio; Misic, Jelena; Simard, Marie-Lune S.; Wolf, Eckhard; Fuchs, Helmut S.; Gailus-Durner, Valerie; Habrě de Angelis, Martin und Larsson, Nils-Göran
(2022):
Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction.
In: PLOS Genetics
18(5), e1010190
Lugara, Rosamaria; Renner, Simone; Wolf, Eckhard; Liesegang, Annette; Bruckmaier, Rupert und Giller, Katrin
(2022):
Crossbred Sows Fed a Western Diet during Pre-Gestation, Gestation, Lactation, and Post-Lactation Periods Develop Signs of Lean Metabolic Syndrome That Are Partially Attenuated by Spirulina Supplementation.
In: Nutrients, Bd. 14, Nr. 17, 3574
Flisikowska, Tatiana; Egli, Jerome; Flisikowski, Krzysztof; Stumbaum, Marlene; Kueng, Erich; Ebeling, Martin; Schmucki, Roland; Georges, Guy; Singer, Thomas; Kurome, Mayuko; Kessler, Barbara; Zakhartchenko, Valeri; Wolf, Eckhard; Weber, Felix; Schnieke, Angelika und Iglesias, Antonio
(2022):
A humanized minipig model for the toxicological testing of therapeutic recombinant antibodies.
In: Nature Biomedical Engineering, Bd. 6, Nr. 11: S. 1248-1256
Feher, Anita; Schnur, Andrea; Muenthaisong, Suchitra; Bellak, Tamas; Ayaydin, Ferhan; Varady, Gyorgy; Kemter, Elisabeth; Wolf, Eckhard und Dinnyes, Andras
(2022):
Establishment and characterization of a novel human induced pluripotent stem cell line stably expressing the iRFP720 reporter.
In: Scientific Reports, Bd. 12, Nr. 1, 9874
Garrett, Lillian; Da Silva-Buttkus, Patricia; Rathkolb, Birgit; Gerlini, Raffaele; Becker, Lore; Sanz-Moreno, Adrian; Seisenberger, Claudia; Zimprich, Annemarie; Aguilar-Pimentel, Antonio; Amarie, Oana V.; Cho, Yi-Li; Kraiger, Markus; Spielmann, Nadine; Calzada-Wack, Julia; Marschall, Susan; Busch, Dirk; Schmitt-Weber, Carsten; Wolf, Eckhard; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hoelter, Sabine M. und de Angelis, Martin Hrabe
(2022):
Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk.
In: Disease Models & Mechanisms, Bd. 15, Nr. 3, dmm049205
[PDF, 2MB]
Duin, Sarah; Bhandarkar, Shreya; Lehmann, Susann; Kemter, Elisabeth; Wolf, Eckhard; Gelinsky, Michael; Ludwig, Barbara und Lode, Anja
(2022):
Viability and Functionality of Neonatal Porcine Islet-like Cell Clusters Bioprinted in Alginate-Based Bioinks.
In: Biomedicines, Bd. 10, Nr. 6, 1420
Xie, Kan; Fuchs, Helmut; Scifo, Enzo; Liu, Dan; Aziz, Ahmad; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; da Silva-Buttkus, Patricia; Calzada-Wack, Julia; Cho, Yi-Li; Deng, Yushuang; Edwards, A. Cole; Garrett, Lillian; Georgopoulou, Christina; Gerlini, Raffaele; Hoelter, Sabine M.; Klein-Rodewald, Tanja; Kramer, Michael; Leuchtenberger, Stefanie; Lountzi, Dimitra; Mayer-Kuckuk, Phillip; Nover, Lena L.; Oestereicher, Manuela A.; Overkott, Clemens; Pearson, Brandon L.; Rathkolb, Birgit; Rozman, Jan; Russ, Jenny; Schaaf, Kristina; Spielmann, Nadine; Sanz-Moreno, Adrian; Stoeger, Claudia; Treise, Irina; Bano, Daniele; Busch, Dirk H.; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Mock, Beverly A.; Salomoni, Paolo; Schmidt-Weber, Carsten; Weiergraber, Marco; Wolf, Eckhard; Wurst, Wolfgang; Gailus-Durner, Valerie; Breteler, Monique M. B.; Hrabe de Angelis, Martin und Ehninger, Dan
(2022):
Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.
In: Nature Communications, Bd. 13, Nr. 1, 6830
[PDF, 7MB]
Poch, Christine M.; Foo, Kylie S.; De Angelis, Maria Teresa; Jennbacken, Karin; Santamaria, Gianluca; Baehr, Andrea; Wang, Qing-Dong; Reiter, Franziska; Hornaschewitz, Nadja; Zawada, Dorota; Bozoglu, Tarik; My, Ilaria; Meier, Anna; Dorn, Tatjana; Hege, Simon; Lehtinen, Miia L.; Tsoi, Yat Long; Hovdal, Daniel; Hyllner, Johan; Schwarz, Sascha; Sudhop, Stefanie; Jurisch, Victoria; Sini, Marcella; Fellows, Mick D.; Cummings, Matthew; Clarke, Jonathan; Baptista, Ricardo; Eroglu, Elif; Wolf, Eckhard; Klymiuk, Nikolai; Lu, Kun; Tomasi, Roland; Dendorfer, Andreas; Gaspari, Marco; Parrotta, Elvira; Cuda, Giovanni; Krane, Markus; Sinnecker, Daniel; Hoppmann, Petra; Kupatt, Christian; Fritsche-Danielson, Regina; Moretti, Alessandra; Chien, Kenneth R. und Laugwitz, Karl-Ludwig
(2022):
Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors.
In: Nature Cell Biology, Bd. 24, Nr. 5: S. 659-671
Geng, Ruizhi; Knoll, Jasmin; Harland, Niklas; Amend, Bastian; Enderle, Markus D.; Linzenbold, Walter; Abruzzese, Tanja; Kalbe, Claudia; Kemter, Elisabeth; Wolf, Eckhard; Schenk, Martin; Stenzl, Arnulf und Aicher, Wilhelm K.
(2022):
Replacing Needle Injection by a Novel Waterjet Technology Grants Improved Muscle Cell Delivery in Target Tissues.
In: Cell Transplantation, Bd. 31
Tritschler, Sophie; Thomas, Moritz; Boettcher, Anika; Ludwig, Barbara; Schmid, Janine; Schubert, Undine; Kemter, Elisabeth; Wolf, Eckhard; Lickert, Heiko und Theis, Fabian J.
(2022):
A transcriptional cross species map of pancreatic islet cells.
In: Molecular Metabolism, Bd. 66, 101595
Grotz, Sophia; Schaefer, Jessica; Wunderlich, Kirsten A.; Ellederova, Zdenka; Auch, Hannah; Baehr, Andrea; Runa-Vochozkova, Petra; Fadl, Janet; Arnold, Vanessa; Ardan, Taras; Veith, Miroslav; Santamaria, Gianluca; Dhom, Georg; Hitzl, Wolfgang; Kessler, Barbara; Eckardt, Christian; Klein, Joshua; Brymova, Anna; Linnert, Joshua; Kurome, Mayuko; Zakharchenko, Valeri; Fischer, Andrea; Blutke, Andreas; Doering, Anna; Suchankova, Stepanka; Popelar, Jiri; Rodriguez-Bocanegra, Eduardo; Dlugaiczyk, Julia; Straka, Hans; May-Simera, Helen; Wang, Weiwei; Laugwitz, Karl-Ludwig; Vandenberghe, Luk H.; Wolf, Eckhard; Nagel-Wolfrum, Kerstin; Peters, Tobias; Motlik, Jan; Fischer, M. Dominik; Wolfrum, Uwe und Klymiuk, Nikolai
(2022):
Early disruption of photoreceptor cell architecture and loss of vision in a humanized pig model of usher syndromes.
In: EMBO Molecular Medicine, Bd. 14, Nr. 4, e14817
2021
Flenkenthaler, Florian; Laendstroem, Erik; Shashikadze, Bachuki; Backman, Mattias; Blutke, Andreas; Philippou-Massier, Julia; Renner, Simone; Hrabe de Angelis, Martin; Wanke, Ruediger; Blum, Helmut; Arnold, Georg J.; Wolf, Eckhard und Froehlich, Thomas
(23. November 2021):
Differential Effects of Insulin-Deficient Diabetes Mellitus on Visceral vs. Subcutaneous Adipose Tissue-Multi-omics Insights From the Munich MIDY Pig Model.
In: Frontiers in Medicine, Bd. 8, 751277
[PDF, 2MB]
Stirm, Michael; Fonteyne, Lina Marie; Shashikadze, Bachuki; Lindner, Magdalena; Chirivi, Maila; Lange, Andreas; Kaufhold, Clara; Mayer, Christian; Medugorac, Ivica; Kessler, Barbara; Kurome, Mayuko; Zakhartchenko, Valeri; Hinrichs, Arne; Kemter, Elisabeth; Krause, Sabine; Wanke, Rüdiger; Arnold, Georg J.; Wess, Gerhard; Nagashima, Hiroshi; de Angelis, Marin Hrabe; Flenkenthaler, Florian; Kobelke, Levin Arne; Bearzi, Claudia; Rizzi, Roberto; Bähr, Andreas; Reese, Sven ORCID: https://orcid.org/0000-0002-4605-9791; Matiasek, Kaspar; Walter, Maggie C.; Kupatt, Christian; Ziegler, Sibylle; Bartenstein, Peter; Fröhlich, Thomas; Klymiuk, Nikolai; Blutke, Andreas und Wolf, Eckhard
(19. November 2021):
A scalable, clinically severe pig model for Duchenne muscular dystrophy.
In: Disease Models & Mechanisms, Bd. 14, Nr. 12
[PDF, 3MB]
Kalla, Daniela; Flisikowski, Krzysztof; Yang, Kaiyuan; Sanguesa, Laura Beltran; Kurome, Mayuko; Kessler, Barbara; Zakhartchenko, Valeri; Wolf, Eckhard; Lickert, Heiko; Saur, Dieter; Schnieke, Angelika und Flisikowska, Tatiana
(8. Oktober 2021):
The Missing Link: Cre Pigs for Cancer Research.
In: Frontiers in Oncology, Bd. 11, 755746
[PDF, 7MB]
Bebbere, Daniela; Ulbrich, Susanne E.; Giller, Katrin; Zakhartchenko, Valeri; Reichenbach, Horst-Dieter; Reichenbach, Myriam; Verma, Paul J.; Wolf, Eckhard; Ledda, Sergio und Hiendleder, Stefan
(14. Mai 2021):
Mitochondrial DNA Depletion in Granulosa Cell Derived Nuclear Transfer Tissues.
In: Frontiers in Cell and Developmental Biology, Bd. 9, 664099
[PDF, 2MB]
Giese, Isabella-Maria; Schilloks, Marie-Christin; Degroote, Roxane L.; Weigand, Maria; Renner, Simone; Wolf, Eckhard; Hauck, Stefanie M. und Deeg, Cornelia A.
(22. Januar 2021):
Chronic Hyperglycemia Drives Functional Impairment of Lymphocytes in Diabetic INSC94Y Transgenic Pigs.
In: Frontiers in Immunology, Bd. 11, 607473
[PDF, 1MB]
Frey, Laura; Zietara, Natalia; Lyszkiewicz, Marcin; Marquardt, Benjamin; Mizoguchi, Yoko; Linder, Monika I.; Liu, Yanshan; Giesert, Florian; Wurst, Wolfgang; Dahlhoff, Maik; Schneider, Marlon R.; Wolf, Eckhard; Somech, Raz und Klein, Christoph
(2021):
Mammalian VPS45 orchestrates trafficking through the endosomal system.
In: Blood, Bd. 137, Nr. 14: S. 1932-1944
Hofmann, Isabel; Kemter, Elisabeth; Fiedler, Sonja; Theobalt, Natalie; Fonteyne, Lina; Wolf, Eckhard; Wanke, Rüdiger und Blutke, Andreas
(2021):
A new method for physical disector analyses of numbers and mean volumes of immunohistochemically labeled cells in paraffin sections.
In: Journal of Neuroscience Methods, Bd. 361, 109272
Rieblinger, Beate; Sid, Hicham; Duda, Denise; Bozoglu, Tarik; Klinger, Romina; Schlickenrieder, Antonina; Lengyel, Kamila; Flisikowski, Krzysztof; Flisikowska, Tatiana; Simm, Nina; Grodziecki, Alessandro; Perleberg, Carolin; Bahr, Andrea; Carrier, Lucie; Kurome, Mayuko; Zakhartchenko, Valeri; Kessler, Barbara; Wolf, Eckhard; Kettler, Lutz; Luksch, Harald; Hagag, Ibrahim T.; Wise, Daniel; Kaufman, Jim; Kaufer, Benedikt B.; Kupatt, Christian; Schnieke, Angelika und Schusser, Benjamin
(2021):
Cas9-expressing chickens and pigs as resources for genome editing in livestock.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 118, Nr. 10, e2022562118
Shashikadze, Bachuki; Flenkenthaler, Florian; Stöckl, Jan B.; Valla, Libera; Renner, Simone; Kemter, Elisabeth; Wolf, Eckhard und Fröhlich, Thomas
(2021):
Developmental Effects of (Pre-)Gestational Diabetes on Offspring: Systematic Screening Using Omics Approaches.
In: Genes, Bd. 12, Nr. 12, 1991
Stirm, Michael; Fonteyne, Lina Marie; Shashikadze, Bachuki; Lindner, Magdalena; Chirivi, Maila; Lange, Andreas; Kaufhold, Clara; Mayer, Christian; Medugorac, Ivica; Kessler, Barbara; Kurome, Mayuko; Zakhartchenko, Valeri; Hinrichs, Arne; Kemter, Elisabeth; Krause, Sabine; Wanke, Rudiger; Arnold, Georg J.; Wess, Gerhard; Nagashima, Hiroshi; de Angelis, Martin Hrabe; Flenkenthaler, Florian; Kobelke, Levin Arne; Bearzi, Claudia; Rizzi, Roberto; Baehr, Andrea; Reese, Sven; Matiasek, Kaspar; Walter, Maggie C.; Kupatt, Christian; Ziegler, Sibylle; Bartenstein, Peter; Froehlich, Thomas; Klymiuk, Nikolai; Blutke, Andreas und Wolf, Eckhard
(2021):
A scalable, clinically severe pig model for Duchenne muscular dystrophy.
In: Disease Models & Mechanisms, Bd. 14, Nr. 12, dmm049285
Theobalt, Natalie; Hofmann, Isabel ORCID: https://orcid.org/0000-0003-4019-9619; Fiedler, Sonja; Renner, Simone; Dhom, Georg; Feuchtinger, Annette; Walch, Axel; Hrabe de Angelis, Martin; Wolf, Eckhard ORCID: https://orcid.org/0000-0002-0430-9510; Wanke, Ruediger und Blutke, Andreas ORCID: https://orcid.org/0000-0001-7824-2681
(2021):
Unbiased analysis of obesity related, fat depot specific changes of adipocyte volumes and numbers using light sheet fluorescence microscopy.
In: PLOS One
16(3), e0248594
[PDF, 3MB]
Walz, Michael; Hoeflich, Christine; Walz, Christina; Ohde, Daniela; Brenmoehl, Julia; Sawitzky, Mandy; Vernunft, Andreas; Zettl, Uwe K.; Holtze, Susanne; Hildebrandt, Thomas B.; Wolf, Eckhard und Hoeflich, Andreas
(2021):
Development of a Sensitive Bioassay for the Analysis of IGF-Related Activation of AKT/mTOR Signaling in Biological Matrices.
In: Cells, Bd. 10, Nr. 3, 482
Weijden, Vera A. van der; Schmidhauser, Meret; Kurome, Mayuko; Knubben, Johannes; Floter, Veronika L.; Wolf, Eckhard und Ulbrich, Susanne E.
(2021):
Transcriptome dynamics in early in vivo developing and in vitro produced porcine embryos.
In: BMC Genomics, Bd. 22, Nr. 1, 139
2020
Vohra, Twinkle; Kemter, Elisabeth; Na, Sun; Dobenecker, Britta; Hinrichs, Arne; Burrello, Jacopo; Gomez-Sanchez, Elise; Gomez-Sanchez, Celso E.; Wang, Jun; Kinker, Isabella-Sabrina; Teupser, Daniel; Fischer, Konrad; Schnieke, Angelika; Peitzsch, Mirko; Eisenhofer, Graeme; Walch, Axel; Reincke, Martin ORCID: https://orcid.org/0000-0002-9817-9875; Wolf, Eckhard und Williams, Tracy Ann
(19. Oktober 2020):
Effect of Dietary Sodium Modulation on Pig Adrenal Steroidogenesis and Transcriptome Profiles.
In: Hypertension, Bd. 76, Nr. 6: S. 1769-1777
[PDF, 907kB]
Ludwig, Barbara; Wolf, Eckhard; Schönmann, Uwe und Ludwig, Stefan
(2020):
Large Animal Models of Diabetes.
In: King, Aileen J. F. (Hrsg.):
Animal Models of Diabetes : Methods and Protocols. Methods in molecular biology, Bd. 2128. New York, NY: Springer. S. 115-134
Kollmus, Heike; Fuchs, Helmut; Lengger, Christoph; Haselimashhadi, Hamed; Bogue, Molly A.; Ostereicher, Manuela A.; Horsch, Marion; Adler, Thure; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; Beckers, Johannes; Calzada-Wack, Julia; Garrett, Lillian; Hans, Wolfgang; Hoelter, Sabine M.; Klein-Rodewald, Tanja; Maier, Holger; Mayer-Kuckuk, Philipp; Miller, Gregor; Moreth, Kristin; Neff, Frauke; Rathkolb, Birgit; Racz, Ildiko; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Busch, Dirk; Graw, Jochen; Klopstock, Thomas; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Onder; Mason, Jeremy; Torres, Arturo; Balling, Rudi; Mehaan, Terry; Gailus-Durner, Valerie; Schughart, Klaus und de Angelis, Martin Hrabe
(2020):
A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.
In: Mammalian Genome, Bd. 31: S. 30-48
[PDF, 3MB]
Reichart, Bruno; Langin, Matthias; Radan, Julia; Mokelke, Maren; Buttgereit, Ines; Ying, Jiawei; Fresch, Ann Kathrin; Mayr, Tanja; Issl, Lara; Buchholz, Stefan; Michel, Sebastian; Ellgass, Reinhard; Mihalj, Maks; Egerer, Stefanie; Baehr, Andrea; Kessler, Barbara; Kemter, Elisabeth; Kurome, Mayuko; Zakhartchenko, Valeri; Steen, Stig; Sjoberg, Trygve; Paskevicius, Audrius; Kruger, Luise; Fiebig, Uwe; Denner, Joachim; Godehardt, Antonia W.; Tonjes, Ralf R.; Milusev, Anastasia; Rieben, Robert; Sfriso, Riccardo; Walz, Christoph; Kirchner, Thomas; Ayares, David; Lampe, Karen; Schonmann, Uwe; Hagl, Christian; Wolf, Eckhard; Klymiuk, Nikolai; Abicht, Jan-Michael und Brenner, Paolo
(2020):
Pig-to-non-human primate heart transplantation: The final step toward clinical xenotransplantation?
In: Journal of Heart and Lung Transplantation, Bd. 39, Nr. 8: S. 751-757
Blechner, Christine; Becker, Lore; Fuchs, Helmut; Rathkolb, Birgit; Prehn, Cornelia; Adler, Thure; Calzada-Wack, Julia; Garrett, Lillian; Gailus-Durner, Valerie; Morellini, Fabio; Conrad, Susanne; Hoelter, Sabine M.; Wolf, Eckhard; Klopstock, Thomas; Adamski, Jerzy; Busch, Dirk; de Angelis, Martin Hrabe; Schmeisser, Michael J. und Windhorst, Sabine
(2020):
Physiological relevance of the neuronal isoform of inositol-1,4,5-trisphosphate 3-kinases in mice.
In: Neuroscience Letters, Bd. 735, 135206
Hedegger, Kathrin; Philippou-Massier, Julia; Krebs, Stefan; Blum, Helmut; Kunzelmann, Stefan; Foerstemann, Klaus; Gimpfl, Martina; Roscher, Adelbert A.; Ensenauer, Regina; Wolf, Eckhard und Dahlhoff, Maik
(2020):
Sex-specific programming effects of parental obesity in pre-implantation embryonic development.
In: International Journal of Obesity, Bd. 44, Nr. 5: S. 1185-1190
Denner, Joachim; Längin, Matthias; Reichart, Bruno; Krüger, Luise; Fiebig, Uwe; Mokelke, Maren; Radan, Julia; Mayr, Tanja; Milusev, Anastasia; Luther, Fabian; Sorvillo, Nicoletta; Rieben, Robert; Brenner, Paolo; Walz, Christoph; Wolf, Eckhard; Roshani, Berit; Stahl-Hennig, Christiane und Abicht, Jan-Michael
(2020):
Impact of porcine cytomegalovirus on long-term orthotopic cardiac xenotransplant survival.
In: Scientific Reports, Bd. 10, Nr. 1, 17531
[PDF, 2MB]
Laengin, Matthias; Reichart, Bruno; Steen, Stig; Sjoberg, Trygve; Paskevicius, Audrius; Liao, Qiuming; Qin, Guangqi; Mokelke, Maren; Mayr, Tanja; Radan, Julia; Issl, Lara; Buttgereit, Ines; Ying, Jiawei; Fresch, Ann Kathrin; Panelli, Alessandro; Egerer, Stefanie; Baehr, Andrea; Kessler, Barbara; Milusev, Anastasia; Sfriso, Riccardo; Rieben, Robert; Ayares, David; Murray, Peter J.; Ellgass, Reinhard; Walz, Christoph; Klymiuk, Nikolai; Wolf, Eckhard; Abicht, Jan-Michael und Brenner, Paolo
(2020):
Cold non-ischemic heart preservation with continuous perfusion prevents early graft failure in orthotopic pig-to-baboon xenotransplantation.
In: Xenotransplantation, Bd. 28, Nr. 1, e12636
[PDF, 1MB]
Jodeleit, Henrika; Milchram, Lisa; Soldo, Regina; Beikircher, Gabriel; Schoenthaler, Silvia; Al-amodi, Omar; Wolf, Eckhard; Beigel, Florian; Weinhaeusel, Andreas; Siebeck, Matthias und Gropp, Roswitha
(2020):
Autoantibodies as diagnostic markers and potential drivers of inflammation in ulcerative colitis.
In: PLOS One
15(2), e0228615
[PDF, 2MB]
Dinnyes, Andras; Schnur, Andrea; Muenthaisong, Suchitra; Bartenstein, Peter; Burcez, Charles-Thibault; Burton, Neal; Cyran, Clemens; Gianello, Pierre; Kemter, Elisabeth; Nemeth, Gabor; Nicotra, Francesco; Prepost, Eszter; Qiu, Yi; Russo, Laura; Wirth, Andras; Wolf, Eckhard; Ziegler, Sibylle und Kobolak, Julianna
(2020):
Integration of nano- and biotechnology for beta-cell and islet transplantation in type-1 diabetes treatment.
In: Cell Proliferation, Bd. 53, Nr. 5, e12785
Tamiyakul, Hathaichanok; Kemter, Elisabeth; Kösters, Miwako; Ebner, Stefanie; Blutke, Andreas; Klymiuk, Nikolai; Flenkenthaler, Florian; Wolf, Eckhard; Arnold, Georg J. und Fröhlich, Thomas
(2020):
Progressive Proteome Changes in the Myocardium of a Pig Model for Duchenne Muscular Dystrophy.
In: Iscience, Bd. 23, Nr. 9, 101516
Ferreira dos Santos, Maria C.; Anderson, Cole P.; Neschen, Susanne; Zumbrennen-Bullough, Kimberly B.; Romney, Steven J.; Kahle-Stephan, Melanie; Rathkolb, Birgit; Gailus-Durner, Valerie; Fuchs, Helmut; Wolf, Eckhard; Rozman, Jan; Hrabe de Angelis, Martin; Cai, Weiling Maggie; Rajan, Malini; Hu, Jennifer; Dedon, Peter C. und Leibold, Elizabeth A.
(2020):
Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification.
In: Nature Communications, Bd. 11, Nr. 1, 296
[PDF, 3MB]
Chhabra, Nirav Florian; Amarie, Oana Veronica; Wu, Moya; Amend, Anna-Lena; Rubey, Marina; Gradinger, Daniel; Irmler, Martin; Beckers, Johannes; Rathkolb, Birgit; Wolf, Eckhard; Feuchtinger, Annette; Huypens, Peter; Teperino, Raffaele; Rozman, Jan; Przemeck, Gerhard K. H. und Hrabe de Angelis, Martin
(2020):
PAX6 mutation alters circadian rhythm and beta cell function in mice without affecting glucose tolerance.
In: Communications Biology, Bd. 3, Nr. 1, 628
Fischer, Konrad; Rieblinger, Beate; Hein, Rabea; Sfriso, Riccardo; Zuber, Julia; Fischer, Andrea; Klinger, Bernhard; Liang, Wei; Flisikowski, Krzysztof; Kurome, Mayuko; Zakhartchenko, Valeri; Kessler, Barbara; Wolf, Eckhard; Rieben, Robert; Schwinzer, Reinhard; Kind, Alexander und Schnieke, Angelika
(2020):
Viable pigs after simultaneous inactivation of porcine MHC class I and three xenoreactive antigen genes GGTA1, CMAH and B4GALNT2.
In: Xenotransplantation, Bd. 27, Nr. 1, e12560
Wuensch, Annegret; Kameritsch, Petra; Sfriso, Riccardo; Jemiller, Eva-Maria; Baehr, Andrea; Kurome, Mayuko; Kessler, Barbara; Kemter, Elisabeth; Kupatt, Christian; Reichart, Bruno; Rieben, Robert; Wolf, Eckhard und Klymiuk, Nikolai
(2020):
Genetically encoded Ca2+-sensor reveals details of porcine endothelial cell activation upon contact with human serum.
In: Xenotransplantation, Bd. 27, Nr. 5, e12585
[PDF, 1MB]
Sluka, Susanna H. M.; Staempfli, Simon F.; Akhmedov, Alexander; Rodewald, Tanja Klein; Sanz-Moreno, Adrian; Horsch, Marion; Grest, Paula; Rothmeier, Andrea S.; Rathkolb, Birgit; Schrewe, Anja; Beckers, Johannes; Neff, Frauke; Wolf, Eckhard; Camici, Giovanni G.; Fuchs, Helmut; Durner, Valerie Gailus; Hrabe de Angelis, Martin; Luescher, Thomas F.; Ruf, Wolfram und Tanner, Felix C.
(2020):
Murine tissue actor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality.
In: Haematologica, Bd. 105, Nr. 10: S. 2484-2495
Zhao, Shan; Todorov, Mihail Ivilinov; Cai, Ruiyao; Ai-Maskari, Rami; Steinke, Hanno; Kemter, Elisabeth; Mai, Hongcheng; Rong, Zhouyi; Warmer, Martin; Stanic, Karen; Schoppe, Oliver; Paetzold, Johannes Christian; Gesierich, Benno; Wong, Milagros N.; Huber, Tobias B.; Duering, Marco; Bruns, Oliver Thomas; Menze, Björn; Lipfert, Jan; Puelles, Victor G.; Wolf, Eckhard; Bechmann, Ingo und Ertuerk, Ali
(2020):
Cellular and Molecular Probing of Intact Human Organs.
In: Cell, Bd. 180, Nr. 4: S. 796-812
[PDF, 4MB]
Lucienne, Marie; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Silva-Buttkus, Patricia da; Garrett, Lillian; Holter, Sabine M.; Mayer-Kuckuk, Philipp; Rathkolb, Birgit; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Busch, Dirk H.; Klopstock, Thomas; Schmidt-Weber, Carsten; Wolf, Eckhard; Wurst, Wolfgang; Forny, Merima; Mathis, Deborah; Fingerhut, Ralph; Froese, D. Sean; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin und Baumgartner, Matthias R.
(2020):
In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria.
In: Biochimica et Biophysica Acta-Molecular Basis of Disease, Bd. 1866, Nr. 3, 165622
[PDF, 2MB]
Riedel, Evamaria O.; Hinrichs, Arne; Kemter, Elisabeth; Dahlhoff, Maik; Backman, Mattias; Rathkolb, Birgit; Prehn, Cornelia; Adamski, Jerzy; Renner, Simone; Blutke, Andreas; Hrabe de Angelis, Martin; Bidlingmaier, Martin; Schopohl, Jochen; Arnold, Georg J.; Fröhlich, Thomas und Wolf, Eckhard
(2020):
Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.
In: Molecular Metabolism, Bd. 36, 100978
Gegenfurtner, Katrin; Fröhlich, Thomas; Flenkenthaler, Florian; Koesters, Miwako; Fritz, Sebastien; Desnoes, Olivier; Le Bourhis, Daniel; Salvetti, Pascal; Sandra, Olivier; Charpigny, Gilles; Mermillod, Pascal; Lonergan, Patrick; Wolf, Eckhard und Arnold, Georg J.
(2020):
Genetic merit for fertility alters the bovine uterine luminal fluid proteome.
In: Biology of Reproduction, Bd. 102, Nr. 3: S. 730-739
Hinrichs, Arne; Riedel, Evamaria O.; Klymiuk, Nikolai; Blutke, Andreas; Kemter, Elisabeth; Laengin, Matthias; Dahlhoff, Maik; Kessler, Barbara; Kurome, Mayuko; Zakhartchenko, Valeri; Jemiller, Eva-Maria; Ayares, David; Bidlingmaier, Martin; Flenkenthaler, Florian; Hrabe de Angelis, Martin; Arnold, Georg J.; Reichart, Bruno; Fröhlich, Thomas und Wolf, Eckhard
(2020):
Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies.
In: Xenotransplantation, Bd. 28, Nr. 2, e12664
Zettler, Silja; Renner, Simone; Kemter, Elisabeth; Hinrichs, Arne; Klymiuk, Nikolai; Backman, Mattias; Riedel, Evamaria Olga; Müller, Christiane; Streckel, Elisabeth; Braun-Reichhart, Christina; Martins, Ana Sofia; Kurome, Mayuko; Kessler, Barbara; Zakhartchenko, Valeri; Flenkenthaler, Florian; Arnold, Georg Josef; Fröhlich, Thomas; Blum, Helmut; Blutke, Andreas; Wanke, Rüdiger und Wolf, Eckhard
(2020):
A decade of experience with genetically tailored pig models for diabetes and metabolic research.
In: Animal Reproduction, Bd. 17, Nr. 3, e20200064
Renner, Simone; Blutke, Andreas; Clauss, Sebastian; Deeg, Cornelia A.; Kemter, Elisabeth; Merkus, Daphne; Wanke, Rüdiger und Wolf, Eckhard
(2020):
Porcine models for studying complications and organ crosstalk in diabetes mellitus.
In: Cell and Tissue Research, Bd. 380, Nr. 2: S. 341-378
2019
Lindner, Magdalena; Gosewisch, Astrid; Eilles, Eva; Branner, Christina; Krämer, Anja; Oos, Rosel; Wolf, Eckhard; Ziegler, Sibylle; Bartenstein, Peter; Brandt, Thomas; Dieterich, Marianne und Zwergal, Andreas
(25. Februar 2019):
Ginkgo biloba Extract EGb 761 Improves Vestibular Compensation and Modulates Cerebral Vestibular Networks in the Rat.
In: Frontiers in Neurology, Bd. 10, 147
[PDF, 4MB]
Segal, Joanna; Muelleder, Michael; Krüger, Antje; Adler, Thure; Scholze-Wittler, Manuela; Becker, Lore; Calzada-Wack, Julia; Garrett, Lillian; Hoelter, Sabine M.; Rathkolb, Birgit; Rozman, Jan; Racz, Ildiko; Fischer, Ralf; Busch, Dirk H.; Neff, Frauke; Klingenspor, Martin; Klopstock, Thomas; Grüning, Nana-Maria; Michel, Steve; Lukaszewska-McGreal, Beata; Voigt, Ingo; Hartmann, Ludger; Timmermann, Bernd; Lehrach, Hans; Wolf, Eckhard; Wurst, Wolfgang; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin H.; Schrewe, Heinrich; Yuneva, Mariia und Ralser, Markus
(2019):
Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.
In: Journal of Inherited Metabolic Disease, Bd. 42, Nr. 5: S. 839-849
[PDF, 3MB]
Krüger, Luise; Laengin, Matthias; Reichart, Bruno; Fiebig, Uwe; Kristiansen, Yannick; Prinz, Carolin; Kessler, Barbara; Egerer, Stefanie; Wolf, Eckhard; Abicht, Jan-Michael und Denner, Joachim
(2019):
Transmission of Porcine Circovirus 3 (PCV3) by Xenotransplantation of Pig Hearts into Baboons.
In: Viruses-Basel, Bd. 11, Nr. 7, 650
Gegenfurtner, Katrin; Fröhlich, Thomas; Koesters, Miwako; Mermillod, Pascal; Locatelli, Yann; Fritz, Sebastien; Salvetti, P.; Forde, Niamh; Lonergan, Patrick; Wolf, Eckhard und Arnold, Georg J.
(2019):
Influence of metabolic status and genetic merit for fertility on proteomic composition of bovine oviduct fluid.
In: Biology of Reproduction, Bd. 101, Nr. 5: S. 893-905
Renner, Simone; Martins, Ana Sofia; Streckel, Elisabeth; Braun-Reichhart, Christina; Backman, Mattias; Prehn, Cornelia; Klymiuk, Nikolai; Bahr, Andrea; Blutke, Andreas; Landbrecht-Schessl, Christina; Wuensch, Annegret; Kessler, Barbara; Kurome, Mayuko; Hinrichs, Arne; Koopmans, Sietse-Jan; Krebs, Stefan; Kemter, Elisabeth; Rathkolb, Birgit; Nagashima, Hiroshi; Blum, Helmut; Ritzmann, Mathias; Wanke, Rüdiger; Aigner, Bernhard; Adamski, Jerzy; de Angelis, Martin Hrabe und Wolf, Eckhard
(2019):
Mild maternal hyperglycemia in INSC93S transgenic pigs causes impaired glucose tolerance and metabolic alterations in neonatal offspring.
In: Disease Models & Mechanisms, Bd. 12, Nr. 8, UNSP dmm039156
[PDF, 2MB]
Backman, Mattias; Flenkenthaler, Florian; Blutke, Andreas; Dahlhoff, Maik; Laendstroem, Erik; Renner, Simone; Philippou-Massier, Julia; Krebs, Stefan; Rathkolb, Birgit; Prehn, Cornelia; Grzybek, Michal; Coskun, Uenal; Rothe, Michael; Adamski, Jerzy; de Angelis, Martin Hrabe; Wanke, Rüdiger; Fröhlich, Thomas; Arnold, Georg J.; Blum, Helmut und Wolf, Eckhard
(2019):
Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus.
In: Molecular Metabolism, Bd. 26: S. 30-44
Hawthorne, Wayne J.; Cowan, Peter J.; Buehler, Leo H.; Yi, Shounan; Bottino, Rita; Pierson, Richard N.; Ahn, Curie; Azimzadeh, Agnes; Cozzi, Emanuele; Gianello, Pierre; Lakey, Jonathan R. T.; Luo, Minhua; Miyagawa, Shuji; Mohiuddin, Muhammad M.; Park, Chung-Gyu; Schuurman, Henk-Jan; Scobie, Linda; Sykes, Megan; Tector, Joseph; Toenjes, Ralf Reinhard; Wolf, Eckhard; Nunez, Jose R. und Wang, Wei
(2019):
Third WHO Global Consultation on Regulatory Requirements for Xenotransplantation Clinical Trials, Changsha, Hunan, China December 12-14, 2018 "The 2018 Changsha Communique" The 10-Year Anniversary of The International Consultation on Xenotransplantation.
In: Xenotransplantation, Bd. 26, Nr. 2, e12513
Kurome, Mayuko; Baehr, Andrea; Simmet, Kilian; Jemiller, Eva-Maria; Egerer, Stefanie; Dahlhoff, Maik; Zakhartchenko, Valeri; Nagashima, Hiroshi; Klymiuk, Nikolai; Kessler, Barbara und Wolf, Eckhard
(2019):
Targeting Gal epitopes for multi-species embryo immunosurgery.
In: Reproduction Fertility and Development, Bd. 31, Nr. 4: S. 820-826
Solga, Roxana; Behrens, Juliane; Ziemann, Anja; Riou, Adrien; Berwanger, Carolin; Becker, Lore; Garrett, Lillian; de Angelis, Martin Hrabe; Fischer, Lisa; Coras, Roland; Barkovits, Katalin; Marcus, Katrin; Mahabir, Esther; Eichinger, Ludwig; Schröder, Rolf; Noegel, Angelika A.; Clemen, Christoph S.; Aguilar-Pimentel, Antonio; Schmidt-Weber, Carsten; Klopstock, Thomas; Adler, Thure; Treisel, Irina; Busch, Dirk H.; Moreth, Kristin; Hoelter, Sabine M.; Zimprich, Annemarie; Wurst, Wolfgang; Amarie, Oana; Graw, Jochen; Rozman, Jan; Calzada-Wack, Julia; Racz, Ildiko; Rathkolb, Birgit; Wolf, Eckhard; Oestereicher, Manuela; Miller, Gregor; Lengger, Christoph; Maier, Holger; Stoeger, Claudia; Leuchtenberger, Stefanie; Gallus-Durner, Valerie und Fuchs, Helmut
(2019):
CRN2 binds to TIMP4 and MMP14 and promotes perivascular invasion of glioblastoma cells.
In: European Journal of Cell Biology, Bd. 98, Nr. 5-8, UNSP 151046
Vetrivel, Sharmilee; Tiso, Natascia; Kuegler, Andrea; Irmler, Martin; Horsch, Marion; Beckers, Johannes; Hladik, Daniela; Giesert, Florian; Gailus-Durner, Valerie; Fuchs, Helmut; Sabrautzki, Sibylle; Angelis, Martin Hrabe de; Graw, Jochen; Adler, Thure; Treise, Irina; Busch, Dirk H.; Aguilar-Pimentel, Antonio; Ollert, Markus; Götz, Alexander; Amarie, Oana; Stoeger, Tobias; Schulz, Holger; Becker, Lore; Klopstock, Thomas; Schrewe, Anja; Spielmann, Nadine; Bekeredjian, Raffi; Garrett, Lillian; Hoelter, Sabine M.; Zimprich, Annemarie; Wurst, Wolfgang; Mayer-Kuckuk, Philipp; Hans, Wolfgang; Rozman, Jan; Klingenspor, Martin; Neff, Frauke; Silva-Buttkus, Patricia da; Calzada-Wack, Julia; Racz, Ildiko; Zimmer, Andreas; Rathkolb, Birgit; Wolf, Eckhard; Prehn, Cornelia; Adamski, Jerzy; Oestereicher, Manuela; Miller, Gregor; Steinkamp, Ralph; Lengger, Christoph; Maier, Holger; Stoeger, Claudia und Leuchtenberger, Stefanie
(2019):
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.
In: Experimental Eye Research, Bd. 188, UNSP 107632
[PDF, 7MB]
Dias, Mariana Castro; Coisne, Caroline; Baden, Pascale; Enzmann, Gaby; Garrett, Lillian; Becker, Lore; Hoelter, Sabine M.; de Angelis, Martin Hrabe; Deutsch, Urban; Engelhardt, Britta; Aguilar-Pimentel, Antonio; Adler, Thure; Busch, Dirk H.; Spielmann, Nadine; Moreth, Kristin; Hans, Wolfgang; Amarie, Oana; Graw, Jochen; Rozman, Jan; Radc, Ildiko; Neff, Frauke; Calzada-Wack, Julia; Rathkolb, Birgit; Wolf, Eckhard; Klopstock, Thomas; Wurst, Wolfgang; Beckers, Johannes; Oestereicher, Manuela; Miller, Gregor; Maier, Holger; Stoeger, Claudia; Leuchtenberger, Stefanie; Gailus-Durner, Valerie und Fuchs, Helmut
(2019):
Claudin-12 is not required for blood-brain barrier tight junction function.
In: Fluids and Barriers of the Cns, Bd. 16, Nr. 1, 30
[PDF, 3MB]
Jensen, Lars R.; Garrett, Lillian; Hoelter, Sabine M.; Rathkolb, Birgit; Racz, Ildiko; Adler, Thure; Prehn, Cornelia; Hans, Wolfgang; Rozman, Jan; Becker, Lore; Aguilar-Pimentel, Juan Antonio; Puk, Oliver; Moreth, Kristin; Dopatka, Monika; Walther, Diego J.; Bohlen und Halbach, Viola von; Rath, Matthias; Delatycki, Martin; Bert, Bettina; Fink, Heidrun; Bluemlein, Katharina; Ralser, Markus; Dijck, Anke van; Kooy, Frank; Stark, Zornitza; Müller, Sabine; Scherthan, Harry; Gecz, Jozef; Wurst, Wolfgang; Wolf, Eckhard; Zimmer, Andreas; Klingenspor, Martin; Graw, Jochen; Klopstock, Thomas; Busch, Dirk; Adamski, Jerzy; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Bohlen und Halbach, Oliver von; Ropers, Hans-Hilger und Kuss, Andreas W.
(2019):
A mouse model for intellectual disability caused by mutations in the X-linked 2 '-O-methyltransferase Ftsj1 gene.
In: Biochimica et Biophysica Acta-Molecular Basis of Disease, Bd. 1865, Nr. 9: S. 2083-2093
Regensburger, Adrian P.; Fonteyne, Lina M.; Juengert, Jörg; Wagner, Alexandra L.; Gerhalter, Teresa; Nagel, Armin M.; Heiss, Rafael; Flenkenthaler, Florian; Qurashi, Matthias; Neurath, Markus F.; Klymiuk, Nikolai; Kemter, Elisabeth; Fröhlich, Thomas; Uder, Michael; Woelfle, Joachim; Rascher, Wolfgang; Trollmann, Regina; Wolf, Eckhard; Waldner, Maximilian J. und Knieling, Ferdinand
(2019):
Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy.
In: Nature Medicine, Bd. 25, Nr. 12
Clauss, Sebastian; Bleyer, Christina; Schuettler, Dominik; Tomsits, Philipp; Renner, Simone; Klymiuk, Nikolai; Wakili, Reza; Massberg, Steffen; Wolf, Eckhard und Kaab, Stefan
(2019):
Animal models of arrhythmia: classic electrophysiology to genetically modified large animals.
In: Nature Reviews Cardiology, Bd. 16, Nr. 8: S. 457-475
Locatelli, Yann; Forde, Niamh; Blum, Helmut; Graf, Alexander; Piegu, Benoit; Mermillod, Pascal; Wolf, Eckhard; Lonergan, Patrick und Saint-Dizier, Marie
(2019):
Relative effects of location relative to the corpus luteum and lactation on the transcriptome of the bovine oviduct epithelium.
In: BMC Genomics, Bd. 20, 233
Duan, Jingyue (Ellie); Shi, Wei; Jue, Nathaniel K.; Jiang, Zongliang; Kuo, Lynn; O'Neill, Rachel; Wolf, Eckhard; Dong, Hong; Zheng, Xinbao; Chen, Jingbo und Tian, Xiuchun (Cindy)
(2019):
Dosage Compensation of the X Chromosomes in Bovine Germline, Early Embryos, and Somatic Tissues.
In: Genome Biology and Evolution, Bd. 11, Nr. 1: S. 242-252
2018
Hinrichs, Arne; Kessler, Barbara; Kurome, Mayuko; Blutke, Andreas; Kemter, Elisabeth; Bernau, Maren; Scholz, Armin M.; Rathkolb, Birgit; Renner, Simone; Bultmann, Sebastian; Leonhardt, Heinrich; Hrabe de Angelis, Martin; Nagashima, Hiroshi; Hoeflich, Andreas; Blum, Werner F.; Bidlingmaier, Martin; Wanke, Rüdiger; Dahlhoff, Maik und Wolf, Eckhard
(2018):
Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver.
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Animal models of obesity and diabetes mellitus.
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Consistent success in life-supporting porcine cardiac xenotransplantation.
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Grill, Jessica I.; Neumann, Jens; Ofner, Andrea; Marschall, Maximilian K.; Zierahn, Heike; Herbst, Andreas; Wolf, Eckhard und Kolligs, Frank T.
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Dro1/Ccdc80 inactivation promotes AOM/DSS-induced colorectal carcinogenesis and aggravates colitis by DSS in mice.
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Multiple genetically modified GTKO/hCD46/HLA‐E/hβ2−mg porcine hearts are protected from complement activation and natural killer cell infiltration during ex vivo perfusion with human blood.
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Early weaning completely eliminates porcine cytomegalovirus from a newly established pig donor facility for xenotransplantation.
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Strong xenoprotective function by single-copy transgenes placed sequentially at a permissive locus.
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Yung, Gisella Puga; Bongoni, Anjan K.; Pradier, Amandine; Madelon, Natacha; Papaserafeim, Maria; Sfriso, Riccardo; Ayares, David L.; Wolf, Eckhard; Klymiuk, Nikolai; Bähr, Andrea; Constantinescu, Mihai A.; Vögelin, Esther; Kiermeir, David; Jenni, Hansjorg; Rieben, Robert und Seebach, Jörg D.
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Release of pig leukocytes and reduced human NK cell recruitment during ex vivo perfusion of HLA-E/human CD46 double-transgenic pig limbs with human blood.
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Fiebig, Uwe; Fischer, Konrad; Bähr, Andrea; Runge, Carolin; Schnieke, Angelika; Wolf, Eckhard und Denner, Joachim
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Porcine endogenous retroviruses: Quantification of the copy number in cell lines, pig breeds, and organs.
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Streptozotocin-induced beta-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain.
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Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
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Defective immuno- and thymoproteasome assembly causes severe immunodeficiency.
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Renner, Simone; Blutke, Andreas; Dobenecker, Britta; Dhom, Georg; Müller, Timo D.; Finan, Brian; Clemmensen, Christoffer; Bernau, Maren; Novak, Istvan; Rathkolb, Birgit; Senf, Steffanie; Zoels, Susanne; Roth, Mirjam; Götz, Anna; Hofmann, Susanna M.; Hrabe de Angelis, Martin; Wanke, Rüdiger; Kienzle, Ellen; Scholz, Armin M.; DiMarchi, Richard; Ritzmann, Mathias; Tschoep, Matthias H. und Wolf, Eckhard
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Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Gottingen minipigs.
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Lavagi, Ilaria; Krebs, Stefan; Simmet, Kilian; Beck, Andrea; Zakhartchenko, Valeri; Wolf, Eckhard und Blum, Helmut
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Single-cell RNA sequencing reveals developmental heterogeneity of blastomeres during major genome activation in bovine embryos.
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Modeling lethal X-linked genetic disorders in pigs with ensured fertility.
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Vogel, Heike; Kamitz, Anne; Hallahan, Nicole; Lebek, Sandra; Schallschmidt, Tanja; Jonas, Wenke; Jaehnert, Markus; Gottmann, Pascal; Zellner, Lisa; Kanzleiter, Timo; Damen, Mareike; Altenhofen, Delsi; Burkhardt, Ralph; Renner, Simone; Dahlhoff, Maik; Wolf, Eckhard; Müller, Timo D.; Blueher, Matthias; Joost, Hans-Georg; Chadt, Alexandra; Al-Hasani, Hadi und Schürmann, Annette
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A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes.
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Xie, Kan; Ryan, Devon P.; Pearson, Brandon L.; Henzel, Kristin S.; Neff, Frauke; Vidal, Ramon O.; Hennion, Magali; Lehmann, Isabelle; Schleif, Melvin; Schröder, Susanne; Adler, Thure; Rathkolb, Birgit; Rozman, Jan; Schütz, Anna-Lena; Prehn, Cornelia; Mickael, Michel E.; Weiergraber, Marco; Adamski, Jerzy; Busch, Dirk H.; Ehninger, Gerhard; Matynia, Anna; Jackson, Walker S.; Wolf, Eckhard; Fuchs, Helmut; Gailus-Durner, Valerie; Bonn, Stefan; Hrabe de Angelis, Martin und Ehninger, Dan
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Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice.
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Andre, Viola; Gaut, Christine; Scheideler, Angelika; Aguilar-Pimentel, Juan A.; Amarie, Oana V.; Becker, Lore; Garrett, Lillian; Hans, Wolfgang; Hölter, Sabine M.; Janik, Dirk; Moreth, Kristin; Neff, Frauke; Östereicher, Manuela; Racz, Ildiko; Rathkolb, Birgit; Rozman, Jan; Bekeredjian, Raffi; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Schmidt-Weber, Carsten; Wolf, Eckhard; Wurst, Wolfgang; Gailus-Durner, Valerie; Brielmeier, Markus; Fuchs, Helmut und Hrabe de Angelis, Martin
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Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.
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Fuchs, Helmut; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Cho, Yi-Li; Garrett, Lillian; Hölter, Sabine M.; Irmler, Martin; Kistler, Martin; Kraiger, Markus; Mayer-Kuckuk, Philipp; Moreth, Kristin; Rathkolb, Birgit; Rozman, Jan; Silva Buttkus, Patricia da; Treise, Irina; Zimprich, Annemarie; Gampe, Kristine; Hutterer, Christine; Stoeger, Claudia; Leuchtenberger, Stefanie; Maier, Holger; Miller, Manuel; Scheideler, Angelika; Wu, Moya; Beckers, Johannes; Bekeredjian, Raffi; Brielmeier, Markus; Busch, Dirk H.; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Schmidt-Weber, Carsten; Stoeger, Tobias; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Oender; Zimmer, Andreas; Gailus-Durner, Valerie und Hrabe de Angelis, Martin
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Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.
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Fiebig, Uwe; Abicht, Jan-Michael; Mayr, Tanja; Laengin, Matthias; Bähr, Andrea; Guethoff, Sonja; Falkenau, Almuth; Wolf, Eckhard; Reichart, Bruno; Shibahara, Tomoyuki und Denner, Joachim
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Distribution of Porcine Cytomegalovirus in Infected Donor Pigs and in Baboon Recipients of Pig Heart Transplantation.
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Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes.
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Denner, Joachim; Morozov, Vladimir A.; Reichart, Bruno; Plotzki, Elena; Fiebig, Uwe; Heinrichs, Gerd; Wolf-van Buerck, Lelia; Abicht, Jan-Michael; Petersen, Björn; Mayr, Tanja; Knauf, Yvonne; Becker, Tamara; Fischer, Konrad; Mätz-Rensing, Kerstin; Schuster, Marion; Bähr, Andrea; Klymiuk, Nikolai; Wynyard, Shaun; Matsumoto, Shinichi; Abalovich, Adrian; Elliott, Robert; Seissler, Jochen; Rotem, Avi; Barkai, Uriel; Ludwig, Barbara; Bornstein, Stefan; Schnieke, Angelika; Niemann, Heiner und Wolf, Eckhard
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New detection methods for porcine viruses: screening of donor pigs and human and non-human primate xenotransplant recipients.
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Grill, Jessica I.; Neumann, Jens; Herbst, Andreas; Ofner, Andrea; Hiltwein, Felix; Marschall, Maximilian K.; Zierahn, Heike; Wolf, Eckhard; Schneider, Marlon R. und Kolligs, Frank T.
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Loss of DRO1/CCDC80 results in obesity and promotes adipocyte differentiation.
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Orthotopic cardiac xenotransplantation of GalKO/hCD46/hTM-transgenic pig hearts into baboons (40 days survival) using a CD40mAb or CD40L-Ab costimulation blockade.
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Analysis of non-gal antibody responses after orthotopic pig to baboon cardiac xenotransplantation.
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Inactivation of the GHR gene - a strategy to overcome excess growth of orthotopic pig-to-baboon cardiac xenografts?
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Immunologic effects of myeloablative pre-treatment and total lymphoid irradiation in heterotopic intrathoracic pig-to-baboon cardiac xenotransplantation.
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Monitoring the activation status of endothelial cells by a genetically encoded calcium-sensor.
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Sfriso, Riccardo; Abicht, Jan; Mayr, Tanja; Bähr, Andrea; Klymiuk, Nikolai; Wolf, Eckhard; Reichart, Bruno und Rieben, Robert
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Evaluation of innate immune activation after ex vivo xenoperfusion of GTKO/Hcd46/HLA-E transgenic pig hearts with human blood.
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Hinkel, Rabea; Höwe, Andrea; Renner, Simone; Ng, Judy; Lee, Seungmin; Klett, Katharina; Kaczmarek, Veronika; Moretti, Alessandra; Laugwitz, Karl-Ludwig; Skroblin, Philipp; Mayr, Manuel; Milting, Hendrik; Dendorfer, Andreas; Reichart, Bruno; Wolf, Eckhard und Kupatt, Christian
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Diabetes Mellitus-Induced Microvascular Destabilization in the Myocardium.
In: Journal of the American College of Cardiology, Bd. 69, Nr. 2: S. 131-143
Kumar, Sudhir; Rathkolb, Birgit; Sabrautzki, Sibylle; Krebs, Stefan; Kemter, Elisabeth; Becker, Lore; Beckers, Johannes; Bekeredjian, Raffi; Brommage, Robert; Calzada-Wack, Julia; Garrett, Lillian; Hölter, Sabine M.; Horsch, Marion; Klingenspor, Martin; Klopstock, Thomas; Moreth, Kristin; Neff, Frauke; Rozman, Jan; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Wolf, Eckhard und Aigner, Bernhard
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Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1(I27N) mutant mice.
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Modification of the fatty acid composition of an obesogenic diet improves the maternal and placental metabolic environment in obese pregnant mice.
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Zimprich, Annemarie; Mroz, Gabi; Meyer zu Reckendorf, Christopher; Anastasiadou, Sofia; Förstner, Philip; Garrett, Lillian; Hölter, Sabine M.; Becker, Lore; Rozman, Jan; Prehn, Cornelia; Rathkolb, Birgit; Moreth, Kristin; Wurst, Wolfgang; Klopstock, Thomas; Klingenspor, Martin; Adamski, Jerzy; Wolf, Eckhard; Bekeredjian, Raffi; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin und Knöll, Bernd
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Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms.
In: Molecular Neurobiology, Bd. 54, Nr. 10: S. 8242-8262
Kemter, Elisabeth; Cohrs, Christian M.; Schäfer, Matthias; Schuster, Marion; Steinmeyer, Klaus; Wolf-van Buerck, Lelia; Wolf, Andrea; Wuensch, Annegret; Kurome, Mayuko; Kessler, Barbara; Zakhartchenko, Valeri; Loehn, Matthias; Ivashchenko, Yuri; Seissler, Jochen; Schulte, Anke M.; Speier, Stephan und Wolf, Eckhard
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INS-eGFP transgenic pigs: a novel reporter system for studying maturation, growth and vascularisation of neonatal islet-like cell clusters.
In: Diabetologia, Bd. 60, Nr. 6: S. 1152-1156
Salminen, Aaro V.; Garrett, Lillian; Schormair, Barbara; Rozman, Jan; Giesert, Florian; Niedermeier, Kristina M.; Becker, Lore; Rathkolb, Birgit; Racz, Ildiko; Klingenspor, Martin; Klopstock, Thomas; Wolf, Eckhard; Zimmer, Andreas; Gailus-Durner, Valerie; Torres, Miguel; Fuchs, Helmut; Hrabe de Angelis, Martin; Wurst, Wolfgang; Hölter, Sabine M. und Winkelmann, Juliane
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Meis1: effects on motor phenotypes and the sensorimotor system in mice.
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The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes.
In: Molecular Metabolism, Bd. 6, Nr. 8: S. 931-940
Beshr, Ghamdan; Sikandar, Asfandyar; Jemiller, Eva-Maria; Klymiuk, Nikolai; Hauck, Dirk; Wagner, Stefanie; Wolf, Eckhard; Koehnke, Jesko und Titz, Alexander
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Photorhabdus luminescens lectin A (PllA): A new probe for detecting -galactoside-terminating glycoconjugates.
In: Journal of Biological Chemistry, Bd. 292, Nr. 48: S. 19935-19951
Kleinwort, Kristina J. H.; Amann, Barbara; Hauck, Stefanie M.; Hirmer, Sieglinde; Blutke, Andreas; Renner, Simone; Uhl, Patrizia B.; Lutterberg, Karina; Sekundo, Walter; Wolf, Eckhard und Deeg, Cornelia A.
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Retinopathy with central oedema in an INSC94Y transgenic pig model of long-term diabetes.
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Kurome, Mayuko; Leuchs, Simon; Kessler, Barbara; Kemter, Elisabeth; Jemiller, Eva-Maria; Foerster, Beatrix; Klymiuk, Nikolai; Zakhartchenko, Valeri und Wolf, Eckhard
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Direct introduction of gene constructs into the pronucleus-like structure of cloned embryos: a new strategy for the generation of genetically modified pigs.
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Kaklamanos, Aimilios; Rozman, Jan; Roulis, Manolis; Karagianni, Niki; Armaka, Maria; Wu, Moya; Brachthäuser, Laura; Calzada-Wack, Julia; Horsch, Marion; Beckers, Johannes; Rathkolb, Birgit; Adler, Thure; Neff, Frauke; Wolf, Eckhard; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin und Kollias, George
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Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression.
In: Scientific Reports, Bd. 7, 2397
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Fischer, Konrad; Rieblinger, Beate; Schäffler, Andrea; Petersen, Bjoern; Schwinzer, Reinhard; Niemann, Heiner; Wolf, Eckhard; Kind, Alexander und Schnieke, Angelika
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Multi-modified donor pigs for xenotransplantation.
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Bongoni, Anjan K.; Salvaris, Evelyn; Nordling, Sofia; Klymiuk, Nikolai; Wolf, Eckhard; Ayares, David L.; Rieben, Robert; Magnusson, Peetra U. und Cowan, Peter J.
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Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood.
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Cohrs, Christian M.; Chen, Chunguang; Jahn, Stephan R.; Stertmann, Julia; Chmelova, Helena; Weitz, Jürgen; Bähr, Andrea; Klymiuk, Nikolai; Steffen, Anja; Ludwig, Barbara; Kamvissi, Virginia; Wolf, Eckhard; Bornstein, Stefan R.; Solimena, Michele und Speier, Stephan
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Vessel Network Architecture of Adult Human Islets Promotes Distinct Cell-Cell Interactions In Situ and Is Altered After Transplantation.
In: Endocrinology, Bd. 158, Nr. 5: S. 1373-1385
Bauersachs, Stefan; Simintiras, Constantine A.; Sturmey, Roger G.; Krebs, Stefan; Bick, Jochen; Blum, Helmut; Wolf, Eckhard; Lonergan, Pat und Forde, Niamh
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Effect of metabolic status on conceptus-maternal interactions on day 19 in dairy cattle: II. Effects on the endometrial transcriptome.
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Franko, Andras; Neschen, Susanne; Rozman, Jan; Rathkolb, Birgit; Aichler, Michaela; Feuchtinger, Annette; Brachthäuser, Laura; Neff, Frauke; Kovarova, Marketa; Wolf, Eckhard; Fuchs, Helmut; Häring, Hans-Ulrich; Peter, Andreas und Hrabě de Angelis, Martin
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Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice.
In: Molecular Metabolism, Bd. 6, Nr. 3: S. 256-266
Reichenbach, M.; Simmet, Kilian; Jung, S.; Fries, R.; Scherzer, J.; Grupp, T.; Pimentel, E.; Emmerling, R.; Goetz, K. U.; Wolf, Eckhard und Reichenbach, H. D.
(2017):
Variation of genomic estimated breeding values within genotyped full-sibs of Fleckvieh bovine embryos.
In: Reproduction in Domestic Animals, Bd. 52: S. 43-44
2016
Fröhlich, Thomas; Kemter, Elisabeth; Flenkenthaler, Florian; Klymiuk, Nikolai; Otte, Kathrin A.; Blutke, Andreas; Krause, Sabine; Walter, Maggie C.; Wanke, Rüdiger; Wolf, Eckhard und Arnold, Georg J.
(2016):
Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy.
In: Scientific Reports, Bd. 6, 33362
[PDF, 2MB]
Palamides, Pia; Jodeleit, Henrika; Föhlinger, Michael; Beigel, Florian; Herbach, Nadja; Müller, Thomas; Wolf, Eckhard; Siebeck, Matthias und Gropp, Roswitha
(2016):
A mouse model for ulcerative colitis based on NOD-scid IL2R gamma(null) mice reconstituted with peripheral blood mononuclear cells from affected individuals.
In: Disease Models & Mechanisms, Bd. 9, Nr. 9: S. 985-997
[PDF, 2MB]
Rieger, Alexandra; Kemter, Elisabeth; Kumar, Sudhir; Popper, Bastian; Aigner, Bernhard; Wolf, Eckhard; Wanke, Rüdiger und Blutke, Andreas
(2016):
Missense Mutation of POU Domain Class 3 Transcription Factor 3 in Pou3f3(L423P) Mice Causes Reduced Nephron Number and Impaired Development of the Thick Ascending Limb of the Loop of Henle.
In: PLOS ONE
11(7), e0158977
[PDF, 7MB]
Fischer, Konrad; Kraner-Scheiber, Simone; Petersen, Björn; Rieblinger, Beate; Buermann, Anna; Flisikowska, Tatiana; Flisikowski, Krzysztof; Christan, Susanne; Edlinger, Marlene; Baars, Wiebke; Kurome, Mayuko; Zakhartchenko, Valeri; Kessler, Barbara; Plotzki, Elena; Szczerbal, Izabela; Switonski, Marek; Denner, Joachim; Wolf, Eckhard; Schwinzer, Reinhard; Niemann, Heiner; Kind, Alexander und Schnieke, Angelika
(2016):
Efficient production of multi-modified pigs for xenotransplantation by 'combineering', gene stacking and gene editing.
In: Scientific Reports, Bd. 6, 29081
[PDF, 1MB]
Bähr, Andrea; Käser, Tobias; Kemter, Elisabeth; Gerner, Wilhelm; Kurome, Mayuko; Baars, Wiebke; Herbach, Nadja; Witter, Kirsti; Wünsch, Annegret; Talker, Stephanie C.; Kessler, Barbara; Nagashima, Hiroshi; Saalmüller, Armin; Schwinzer, Reinhard; Wolf, Eckhard und Klymiuk, Nikolai
(2016):
Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs.
In: PLOS ONE
11(5), e0155676
[PDF, 18MB]
Mohiuddin, Muhammad M.; Singh, Avneesh K.; Corcoran, Philip C.; Thomas, Marvin L.; Clark, Tannia; Lewis, Billeta G.; Hoyt, Robert F.; Eckhaus, Michael; Pierson, Richard N.; Belli, Aaron J.; Wolf, Eckhard; Klymiuk, Nikolai; Phelps, Carol; Reimann, Keith A.; Ayares, David und Horvath, Keith A.
(2016):
Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft.
In: Nature Communications, Bd. 7, 11138
[PDF, 1MB]
Kumar, Sudhir; Rathkolb, Birgit; Kemter, Elisabeth; Sabrautzki, Sibylle; Michel, Dian; Adler, Thure; Becker, Lore; Beckers, Johannes; Busch, Dirk H.; Garrett, Lillian; Hans, Wolfgang; Hölter, Sabine M.; Horsch, Marion; Klingenspor, Martin; Klopstock, Thomas; Rácz, Ildikó; Rozman, Jan; Panesso, Ingrid Liliana Vargas; Vernaleken, Alexandra; Zimmer, Andreas; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Wolf, Eckhard und Aigner, Bernhard
(2016):
Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3(L423P) Mutant Mice.
In: PLOS ONE
11(3), e0150472
[PDF, 1MB]
Hoeflich, Andreas; Reyer, Anja; Ohde, Daniela; Schindler, Nancy; Brenmoehl, Julia; Spitschak, Marion; Langhammer, Martina; Tuchscherer, Armin; Wirthgen, Elisa; Renner-Müller, Ingrid; Wanke, Rüdiger; Metzger, Friedrich; Bielohuby, Maximilian und Wolf, Eckhard
(2016):
Dissociation of somatic growth, time of sexual maturity, and life expectancy by overexpression of an RGD-deficient IGFBP-2 variant in female transgenic mice.
In: Aging Cell, Bd. 15, Nr. 1: S. 111-117
[PDF, 355kB]
Mulay, Shrikant R.; Eberhard, Jonathan N.; Pfann, Victoria; Marschner, Julian A.; Darisipudi, Murthy N.; Daniel, Christoph; Romoli, Simone; Desai, Jyaysi; Grigorescu, Melissa; Kumar, Santhosh V.; Rathkolb, Birgit; Wolf, Eckhard; de Angelis, Martin Hrabe; Bäuerle, Tobias; Dietel, Barbara; Wagner, Carsten A.; Amann, Kerstin; Eckardt, Kai-Uwe; Aronson, Peter S.; Anders, Hans Joachim und Knauf, Felix
(2016):
Oxalate-induced chronic kidney disease with its uremic and cardiovascular complications in C57BL/6 mice.
In: American Journal of Physiology: Renal Physiology, Bd. 310, Nr. 8:
F785-F795
Fuchs, Helmut; Sabrautzki, Sibylle; Przemeck, Gerhard K. H.; Leuchtenberger, Stefanie; Lorenz-Depiereux, Bettina; Becker, Lore; Rathkolb, Birgit; Horsch, Marion; Garrett, Lillian; Östereicher, Manuela A.; Hans, Wolfgang; Abe, Koichiro; Sagawa, Nobuho; Rozman, Jan; Vargas-Panesso, Ingrid L.; Sandholzer, Michael; Lisse, Thomas S.; Adler, Thure; Aguilar-Pimentel, Juan Antonio; Calzada-Wack, Julia; Ehrhard, Nicole; Elvert, Ralf; Gau, Christine; Hölter, Sabine M.; Micklich, Katja; Moreth, Kristin; Prehn, Cornelia; Puk, Oliver; Racz, Ildiko; Stoeger, Claudia; Vernaleken, Alexandra; Michel, Dian; Diener, Susanne; Wieland, Thomas; Adamski, Jerzy; Bekeredjian, Raffi; Busch, Dirk H.; Favor, John; Graw, Jochen; Klingenspor, Martin; Lengger, Christoph; Maier, Holger; Neff, Frauke; Ollert, Markus; Stoeger, Tobias; Yildirim, Ali Önder; Strom, Tim M.; Zimmer, Andreas; Wolf, Eckhard; Wurst, Wolfgang; Klopstock, Thomas; Beckers, Johannes; Gailus-Durner, Valerie und Hrabé de Angelis, Martin
(2016):
The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.
In: G3-Genes Genomes Genetics, Bd. 6, Nr. 12: S. 4035-4046
Weiß, Marlene; Kost, Bernd; Renner-Müller, Ingrid; Wolf, Eckhard; Mylonas, Ioannis und Brüning, Ansgar
(2016):
Efavirenz Causes Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy in Endothelial Cells.
In: Cardiovascular Toxicology, Bd. 16, Nr. 1: S. 90-99
Sabrautzki, Sibylle; Sandholzer, Michael A.; Lorenz-Depiereux, Bettina; Brommage, Robert; Przemeck, Gerhard; Panesso, Ingrid L. Vargas; Vernaleken, Alexandra; Garrett, Lillian; Baron, Katharina; Yildirim, Ali O.; Rozman, Jan; Rathkolb, Birgit; Gau, Christine; Hans, Wolfgang; Hoelter, Sabine M.; Marschall, Susan; Stoeger, Claudia; Becker, Lore; Fuchs, Helmut; Gailus-Durner, Valerie; Klingenspor, Martin; Klopstock, Thomas; Lengger, Christoph; Stefanie, Leuchtenberger; Wolf, Eckhard; Strom, Tim M.; Wurst, Wolfgang und Hrabě de Angelis, Martin
(2016):
Viable Ednra (Y129F) mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation.
In: Mammalian Genome, Bd. 27, Nr. 11-12: S. 587-598
Rataj, Dennis; Werwitzke, Sonja; Haarmeijer, Birgitt; Winkler, Michael; Ramackers, Wolf; Petersen, Björn; Niemann, Heiner; Wünsch, Annegret; Bähr, Andrea; Klymiuk, Nikolai; Wolf, Eckhard; Abicht, Jan-Michael; Ayares, David und Tiede, Andreas
(2016):
Inhibition of complement component C5 prevents clotting in an ex vivo model of xenogeneic activation of coagulation.
In: Xenotransplantation, Bd. 23, Nr. 2: S. 117-127
Franko, Andras; Huypens, Peter; Neschen, Susanne; Irmler, Martin; Rozman, Jan; Rathkolb, Birgit; Neff, Frauke; Prehn, Cornelia; Dubois, Guillaume; Baumann, Martina; Massinger, Rebecca; Gradinger, Daniel; Przemeck, Gerhard K. H.; Repp, Birgit; Aichler, Michaela; Feuchtinger, Annette; Schommers, Philipp; Stöhr, Oliver; Sanchez-Lasheras, Carmen; Adamski, Jerzy; Peter, Andreas; Prokisch, Holger; Beckers, Johannes; Walch, Axel K.; Fuchs, Helmut; Wolf, Eckhard; Schubert, Markus; Wiesner, Rudolf J. und de Angelis, Martin Hrabe
(2016):
Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice.
In: Diabetes, Bd. 65, Nr. 9: S. 2540-2552
Förster, Reinhold; Schubel, Andreas; Breitfeld, Dagmar; Kremmer, Elisabeth; Renner-Müller, Ingrid; Wolf, Eckhard und Lipp, Martin
(2016):
CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs (Reprinted from Cell, vol 99, pg 23-33, 1999).
In: Journal of Immunology, Bd. 196, Nr. 1: S. 5-15
Schlosser, Anders; Pilecki, Bartosz; Hemstra, Line E.; Kejling, Karin; Kristmannsdottir, Gudlaug B.; Wulf-Johansson, Helle; Moeller, Jesper B.; Füchtbauer, Ernst-Martin; Nielsen, Ole; Kirketerp-Møller, Katrine; Dubey, Lalit K.; Hansen, Pernille B. L.; Stubbe, Jane; Wrede, Christoph; Hegermann, Jan; Ochs, Matthias; Rathkolb, Birgit; Schrewe, Anja; Bekeredjian, Raffi; Wolf, Eckhard; Gailus-Durner, Valérie; Fuchs, Helmut; Hrabě de Angelis, Martin; Lindholt, Jes S.; Holmskov, Uffe und Sorensen, Grith L.
(2016):
MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 36, Nr. 1: S. 122-133
Kourtzelis, Ioannis; Kotlabova, Klara; Lim, Jong-Hyung; Mitroulis, Ioannis; Ferreira, Anaisa; Chen, Lan-Sun; Gercken, Bettina; Steffen, Anja; Kemter, Elisabeth; Klotzsche-von Ameln, Anne; Waskow, Claudia; Hosur, Kavita; Chatzigeorgiou, Antonios; Ludwig, Barbara; Wolf, Eckhard; Hajishengallis, George und Chavakis, Triantafyllos
(2016):
Developmental endothelial locus-1 modulates platelet-monocyte interactions and instant blood-mediated inflammatory reaction in islet transplantation.
In: Thrombosis and Haemostasis, Bd. 115, Nr. 4: S. 781-788
Deeg, Cornelia A.; Uhl, Patrizia; Amann, Barbara; Blutke, Andreas; Renner, Simone; Hirmer, Sieglinde; Merl-Pham, Juliane; Sekundo, Walter; Wanke, Ruediger; Wolf, Eckhard und Hauck, Stefanie M.
(2016):
The INSC94Y transgenic pig: a novel model for diabetic retinopathy with macular edema.
In: Investigative Ophthalmology & Visual Science, Bd. 57, Nr. 12
Diener, Susanne; Bayer, Sieglinde; Sabrautzki, Sibylle; Wieland, Thomas; Mentrup, Birgit; Przemeck, Gerhard K. H.; Rathkolb, Birgit; Graf, Elisabeth; Hans, Wolfgang; Fuchs, Helmut; Horsch, Marion; Schwarzmayr, Thomas; Wolf, Eckhard; Klopocki, Eva; Jakob, Franz; Strom, Tim M.; Hrabě de Angelis, Martin und Lorenz-Depiereux, Bettina
(2016):
Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia.
In: Mammalian Genome, Bd. 27, Nr. 3-4: S. 111-121
Korner, Germaine; Scherer, Tanja; Adamsen, Dea; Rebuffat, Alexander; Crabtree, Mark; Rassi, Anahita; Scavelli, Rossana; Homma, Daigo; Ledermann, Birgit; Konrad, Daniel; Ichinose, Hiroshi; Wolfrum, Christian; Horsch, Marion; Rathkolb, Birgit; Klingenspor, Martin; Beckers, Johannes; Wolf, Eckhard; Gailus-Durner, Valérie; Fuchs, Helmut; Hrabě de Angelis, Martin; Blau, Nenad; Rozman, Jan und Thöny, Beat
(2016):
Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice.
In: Journal of inherited Metabolic Disease, Bd. 39, Nr. 2: S. 309-319
Albl, Barbara; Haesner, Serena; Braun-Reichhart, Christina; Streckel, Elisabeth; Renner, Simone; Seeliger, Frank; Wolf, Eckhard; Wanke, Rüdiger und Blutke, Andreas
(2016):
Tissue Sampling Guides for Porcine Biomedical Models.
In: Toxicologic Pathology, Bd. 44, Nr. 3: S. 414-420
[PDF, 142kB]
Otto, Gordon P.; Rathkolb, Birgit; Oestereicher, Manuela A.; Lengger, Christoph J.; Moerth, Corinna; Micklich, Kateryna; Fuchs, Helmut; Gailus-Durner, Valerie; Wolf, Eckhard und Hrabe de Angelis, Martin
(2016):
Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ Mice (Mus musculus).
In: Journal of the American Association for Laboratory Animal Science, Bd. 55, Nr. 4: S. 375-386
2015
Popken, Jens; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Schmid, Volker J. ORCID: https://orcid.org/0000-0003-2195-8130; Strauss, Axel; Guengoer, Tuna; Zakhartchenko, Valeri; Wolf, Eckhard und Cremer, Thomas
(2015):
Remodeling of the Nuclear Envelope and Lamina during Bovine Preimplantation Development and Its Functional Implications.
In: PLOS ONE
10(5), e0124619
[PDF, 9MB]
Guillon, Antoine; Chevaleyre, Claire; Barc, Celine; Berri, Mustapha; Adriaensen, Hans; Lecompte, Francois; Villemagne, Thierry; Pezant, Jeremy; Delaunay, Remi; Moenne-Loccoz, Joseph; Berthon, Patricia; Baehr, Andrea; Wolf, Eckhard; Klymiuk, Nikolai; Attucci, Sylvie; Ramphal, Reuben; Sarradin, Pierre; Buzoni-Gatel, Dominique; Si-Tahar, Mustapha und Caballero, Ignacio
(2015):
Computed Tomography (CT) Scanning Facilitates Early Identification of Neonatal Cystic Fibrosis Piglets.
In: PLOS ONE
10(11), e0143459
[PDF, 2MB]
Brina, Daniela; Miluzio, Annarita; Ricciardi, Sara; Clarke, Kim; Davidsen, Peter K.; Viero, Gabriella; Tebaldi, Toma; Offenhaeuser, Nina; Rozman, Jan; Rathkolb, Birgit; Neschen, Susanne; Klingenspor, Martin; Wolf, Eckhard; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin Hrabe; Quattrone, Alessandro; Falciani, Francesco und Biffo, Stefano
(2015):
eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription.
In: Nature Communications, Bd. 6, 8261
[PDF, 2MB]
Streckel, Elisabeth; Braun-Reichhart, Christina; Herbach, Nadja; Dahlhoff, Maik; Kessler, Barbara; Blutke, Andreas; Bähr, Andrea; Übel, Nicole; Eddicks, Matthias; Ritzmann, Mathias; Krebs, Stefan; Göke, Burkhard; Blum, Helmut; Wanke, Rüdiger; Wolf, Eckhard und Renner, Simone
(2015):
Effects of the glucagon-like peptide-1 receptor agonist liraglutide in juvenile transgenic pigs modeling a pre-diabetic condition.
In: Journal of Translational Medicine
13
[PDF, 1MB]
2014
Popken, Jens; Brero, Alessandro; Koehler, Daniela; Schmid, Volker J. ORCID: https://orcid.org/0000-0003-2195-8130; Strauss, Axel; Wuensch, Annegret; Guengoer, Tuna; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Zakhartchenko, Valeri; Wolf, Eckhard und Cremer, Thomas
(2014):
Reprogramming of fibroblast nuclei in cloned bovine embryos involves major structural remodeling with both striking similarities and differences to nuclear phenotypes of in vitro fertilized embryos.
In: Nucleus, Bd. 5, Nr. 6: S. 555-589
Popken, Jens; Dahlhoff, Maik; Guengoer, Tuna; Schmid, Volker J. ORCID: https://orcid.org/0000-0003-2195-8130; Strauss, Axel; Cremer, Thomas; Zakhartchenko, Valeri und Wolf, Eckhard
(2014):
Nuclear invaginations adapt to rabbit early embryonic developement.
In: Reproduction, Fertility and Development, Bd. 27, Nr. 1: S. 139
Horsch, Marion; Beckers, Johannes; Fuchs, Helmut; Gailus-Durner, Valérie; Hrabě de Angelis, Martin; Rathkolb, Birgit; Wolf, Eckhard; Aigner, Bernhard und Kemter, Elisabeth
(2014):
Uromodulin Retention in Thick Ascending Limb of Henle's Loop Affects SCD1 in Neighboring Proximal Tubule: Renal Transcriptome Studies in Mouse Models of Uromodulin-Associated Kidney Disease.
In: PLOS ONE
9(11), e113125
[PDF, 911kB]
Keller, Johannes; Catala-Lehnen, Philip; Huebner, Antje K.; Jeschke, Anke; Heckt, Timo; Lueth, Anja; Krause, Matthias; Koehne, Till; Albers, Joachim; Schulze, Jochen; Schilling, Sarah; Haberland, Michael; Denninger, Hannah; Neven, Mona; Hermans-Borgmeyer, Irm; Streichert, Thomas; Breer, Stefan; Barvencik, Florian; Levkau, Bodo; Rathkolb, Birgit; Wolf, Eckhard; Calzada-Wack, Julia; Neff, Frauke; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabě de Angelis, Martin; Klutmann, Susanne; Tsourdi, Elena; Hofbauer, Lorenz C.; Kleuser, Burkhard; Chun, Jerold; Schinke, Thorsten und Amling, Michael
(2014):
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts.
In: Nature Communications, Bd. 5, 5215
[PDF, 1MB]
Kraus, Petra; Sivakamasundari, V; Yu, Hong Bing; Xing, Xing; Lim, Siew Lan; Adler, Thure; Pimentel, Juan Antonio Aguilar; Becker, Lore; Bohla, Alexander; Garrett, Lillian; Hans, Wolfgang; Hölter, Sabine M.; Janas, Eva; Moreth, Kristin; Prehn, Cornelia; Puk, Oliver; Rathkolb, Birgit; Rozman, Jan; Adamski, Jerzy; Bekeredjian, Raffi; Busch, Dirk H.; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Neff, Frauke; Ollert, Markus; Stoeger, Tobias; Yildrim, Ali Önder; Eickelberg, Oliver; Wolf, Eckhard; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabě de Angelis, Martin; Lufkin, Thomas und Stanton, Lawrence W.
(2014):
Pleiotropic Functions for Transcription Factor Zscan10.
In: PLOS ONE
9(8), e104568
[PDF, 3MB]
Kemter, Elisabeth; Rathkolb, Birgit; Becker, Lore; Bolle, Ines; Busch, Dirk H.; Dalke, Claudia; Elvert, Ralf; Favor, Jack; Graw, Jochen; Hans, Wolfgang; Ivandic, Boris; Kalaydjiev, Svetoslav; Klopstock, Thomas; Rácz, Ildikó; Rozman, Jan; Schrewe, Anja; Schulz, Holger; Zimmer, Andreas; Fuchs, Helmut; Gailus-Durner, Valérie; Hrabé de Angelis, Martin; Wolf, Eckhard und Aigner, Bernhard
(2014):
Standardized, systemic phenotypic analysis of Slc12a(1299F) mutant mice.
In: Journal of Biomedical Science
21:68
[PDF, 493kB]
Li, Shun; Flisikowska, Tatiana; Kurome, Mayuko; Zakhartchenko, Valeri; Kessler, Barbara; Saur, Dieter; Kind, Alexander; Wolf, Eckhard; Flisikowski, Krzysztof und Schnieke, Angelika
(2014):
Dual Fluorescent Reporter Pig for Cre Recombination: Transgene Placement at the ROSA26 Locus.
In: PLOS ONE
9(7), e102455
[PDF, 960kB]
Zumbrennen-Bullough, Kimberly B.; Becker, Lore; Garrett, Lillian; Hölter, Sabine M.; Calzada-Wack, Julia; Mossbrugger, Ilona; Quintanilla-Fend, Leticia; Racz, Ildiko; Rathkolb, Birgit; Klopstock, Thomas; Wurst, Wolfgang; Zimmer, Andreas; Wolf, Eckhard; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabé de Angelis, Martin; Romney, Steven J. und Leibold, Elizabeth A.
(2014):
Abnormal Brain Iron Metabolism in Irp2 Deficient Mice Is Associated with Mild Neurological and Behavioral Impairments.
In: PLOS ONE
9(6), e98072
[PDF, 5MB]
2013
Bongoni, Anjan K.; Kiermeir, David; Jenni, Hansjoerg; Wünsch, Annegret; Bähr, Andrea; Ayares, David; Seebach, Joerg D.; Wolf, Eckhard; Klymiuk, Nikolai; Constantinescu, Mihai A.; Voegelin, Esther und Rieben, Robert
(November 2013):
Activation of the Lectin Pathway of Complement in Pig-to-Human Xenotransplantation Models.
In: Transplantation, Bd. 96, Nr. 9: S. 791-799
[PDF, 17MB]
Bebbere, Daniela; Bauersachs, Stefan; Fürst, Rainer W; Medugorac, Ivica; Reichenbach, Horst-Dieter; Reichenbach, Myriam; Ulbrich, Susanne E; Wolf, Eckhard; Ledda, Sergio und Hiendleder, Stefan
(8. April 2013):
Tissue-Specific and Minor Inter-Individual Variation in Imprinting of IGF2R Is a Common Feature of Bos taurus Concepti and Not Correlated with Fetal Weight.
In: PLOS ONE
8(4), e59564
[PDF, 943kB]
Pozzi, Benedetta; Amodio, Stefania; Lucano, Caterina; Sciullo, Anna; Ronzoni, Simona; Castelletti, Daniela; Adler, Thure; Treise, Irina; Betsholtz, Ingrid Holmberg; Rathkolb, Birgit; Busch, Dirk H.; Wolf, Eckhard; Fuchs, Helmut; Gailus-Durner, Valérie; Hrabé de Angelis, Martin; Betsholtz, Christer; Casola, Stefano; Di Fiore, Pier Paolo und Offenhäuser, Nina
(2013):
Correction: The Endocytic Adaptor Eps15 Controls Marginal Zone B Cell Numbers.
In: PLOS ONE
8(5)
[PDF, 2MB]
Venit, Tomáš; Dzijak, Rastislav; Kalendová, Alžběta; Kahle, Michal; Rohožková, Jana; Schmidt, Volker; Rülicke, Thomas; Rathkolb, Birgit; Hans, Wolfgang; Bohla, Alexander; Eickelberg, Oliver; Stoeger, Tobias; Wolf, Eckhard; Yildirim, Ali Önder; Gailus-Durner, Valérie; Fuchs, Helmut; Hrabé de Angelis, Martin und Hozák, Pavel
(2013):
Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus.
In: PLOS ONE
8(4), e61406
[PDF, 876kB]
Kurome, Mayuko; Geistlinger, Ludwig; Kessler, Barbara; Zakhartchenko, Valeri; Klymiuk, Nikolai; Wuensch, Annegret; Richter, Anne; Baehr, Andrea; Kraehe, Katrin; Burkhardt, Katinka; Flisikowski, Krzysztof; Flisikowska, Tatiana; Merkl, Claudia; Landmann, Martina; Durkovic, Marina; Tschukes, Alexander; Kraner, Simone; Schindelhauer, Dirk; Petri, Tobias; Kind, Alexander; Nagashima, Hiroshi; Schnieke, Angelika; Zimmer, Ralf und Wolf, Eckhard
(2013):
Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set.
In: BMC Biotechnology
13:43
[PDF, 617kB]
Zadeh-Khorasani, Maryam; Nolte, Thomas; Mueller, Thomas D.; Pechlivanis, Markos; Rueff, Franziska; Wollenberg, Andreas; Fricker, Gert; Wolf, Eckhard; Siebeck, Matthias und Gropp, Roswitha
(2013):
NOD-scid IL2R gamma(null) mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways.
In: Journal of Translational Medicine
11:4
[PDF, 875kB]
Kemter, Elisabeth; Prueckl, Petra; Sklenak, Stefanie; Rathkolb, Birgit; Habermann, Felix A.; Hans, Wolfgang; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Wolf, Eckhard; Aigner, Bernhard und Wanke, Rüdiger
(2013):
Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice.
In: Human molecular genetics, Bd. 22, Nr. 20: S. 4148-4163
[PDF, 1MB]
2012
Bauersachs, Stefan; Ulbrich, Susanne E.; Reichenbach, Horst-Dieter; Reichenbach, Myriam; Büttner, Mathias; Meyer, Heinrich H. D.; Spencer, Thomas E.; Minten, Megan; Sax, Gerhard; Winter, Gerhard und Wolf, Eckhard
(27. Oktober 2012):
Comparison of the Effects of Early Pregnancy with Human Interferon, Alpha 2 (IFNA2), on Gene Expression in Bovine Endometrium.
In: Biology of reproduction, Bd. 86, Nr. 2: S. 1-15
[PDF, 664kB]
Olszewski, Pawel K.; Rozman, Jan; Jacobsson, Josefin A.; Rathkolb, Birgit; Stromberg, Siv; Hans, Wolfgang; Klockars, Anica; Alsio, Johan; Riserus, Ulf; Becker, Lore; Hoelter, Sabine M.; Elvert, Ralf; Ehrhardt, Nicole; Gailus-Durner, Valerie; Fuchs, Helmut; Fredriksson, Robert; Wolf, Eckhard; Klopstock, Thomas; Wurst, Wolfgang; Levine, Allen S.; Marcus, Claude; Hrabé de Angelis, Martin; Klingenspor, Martin; Schiöth, Helgi B. und Kilimann, Manfred W.
(März 2012):
Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans.
In: PLOS Genetics
8(3), e1002568.
[PDF, 644kB]
Leuchs, Simon; Saalfrank, Anja; Merkl, Claudia; Flisikowska, Tatiana; Edlinger, Marlene; Durkovic, Marina; Rezaei, Nousin; Kurome, Mayuko; Zakhartchenko, Valeri; Kessler, Barbara; Flisikowski, Krzysztof; Kind, Alexander; Wolf, Eckhard und Schnieke, Angelika
(2012):
Inactivation and inducible oncogenic mutation of p53 in gene targeted pigs.
In: PLOS ONE
7(10), e43323
[PDF, 592kB]
Staropoli, John F.; Haliw, Larissa; Biswas, Sunita; Garrett, Lillian; Hölter, Sabine M.; Becker, Lore; Skosyrski, Sergej; Silva-Buttkus, Patricia da; Calzada-Wack, Julia; Neff, Frauke; Rathkolb, Birgit; Rozman, Jan; Schrewe, Anja; Adler, Thure; Puk, Oliver; Sun, Minxuan; Favor, Jack; Racz, Ildikó; Bekeredjian, Raffi; Busch, Dirk H.; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Wolf, Eckhard; Wurst, Wolfgang; Zimmer, Andreas; Lopez, Edith; Harati, Hayat; Hill, Eric; Krause, Daniela S.; Guide, Jolene; Dragileva, Ella; Gale, Evan; Wheeler, Vanessa C.; Boustany, Rose-Mary; Brown, Diane E.; Breton, Sylvie; Ruether, Klaus; Gailus-Durner, Valérie; Fuchs, Helmut; Hrabé de Angelis, Martin und Cotman, Susan L.
(2012):
Large-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system.
In: PLOS ONE
7(6), e38310
[PDF, 4MB]
Mohr, Hermine; Mohr, Christian A.; Schneider, Marlon R.; Scrivano, Laura; Adler, Barbara; Kraner-Scheiber, Simone; Schnieke, Angelika; Dahlhoff, Maik; Wolf, Eckhard; Koszinowski, Ulrich H. und Ruzsics, Zsolt
(2012):
Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo.
In: PLOS Pathogens
8(6), e1002728
[PDF, 2MB]
Streyl, Dominik; Kenngott, Rebecca; Herbach, Nadja; Wanke, Rüdiger; Blum, Helmut; Sinowatz, Fred; Wolf, Eckhard; Zerbe, Holm und Bauersachs, Stefan
(2012):
Gene expression profiling of bovine peripartal placentomes: detection of molecular pathways potentially involved in the release of foetal membranes.
In: Reproduction, Bd. 143, Nr. 1: S. 85-105
[PDF, 826kB]
2011
Leidenfrost, Sandra; Boelhauve, Marc; Reichenbach, Myriam; Güngör, Tuna; Reichenbach, Horst-Dieter; Sinowatz, Fred; Wolf, Eckhard und Habermann, Felix A.
(2011):
Cell arrest and cell death in mammalian preimplantation development. Lessons from the bovine model.
In: PLOS ONE
6(7), e22121
[PDF, 609kB]
2010
Schneider, Marlon R.; Dahlhoff, Maik; Horst, David; Hirschi, Benjamin; Trülzsch, Konrad; Müller-Höcker, Josef; Vogelmann, Roger; Allgäuer, Michael; Gerhard, Markus; Steininger, Sylvia; Wolf, Eckhard und Kolligs, Frank T.
(2010):
A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation.
In: PLOS ONE
5(12), e14325
[PDF, 21MB]
Tocchetti, Arianna; Soppo, Charlotte Blanche Ekalle; Zani, Fabio; Bianchi, Fabrizio; Gagliani, Maria Cristina; Pozzi, Benedetta; Rozman, Jan; Elvert, Ralf; Ehrhardt, Nicole; Rathkolb, Birgit; Moerth, Corinna; Horsch, Marion; Fuchs, Helmut; Gailus-Durner, Valérie; Beckers, Johannes; Klingenspor, Martin; Wolf, Eckhard; Hrabé de Angelis, Martin; Scanziani, Eugenio; Tacchetti, Carlo; Scita, Giorgio; Di Fiore, Pier Paolo und Offenhäuser, Nina
(2010):
Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice.
In: PLOS ONE
5(3), e9468
[PDF, 2MB]
de Montera, Béatrice; Zeihery, Dalia E.; Müller, Sigrid; Jammes, Hélène; Brem, Gottfried; Reichenbach, Horst-Dietrich; Scheipl, Fabian; Chavatte-Palmer, Pascale; Zakhartchenko, Valeri; Schmitz, Oliver J.; Wolf, Eckhard; Renard, Jean-Paul und Hiendleder, Stefan
(2010):
Quantification of Leukocyte Genomic 5-Methylcytosine Levels Reveals Epigenetic Plasticity in Healthy Adult Cloned Cattle.
In: Cellular Reprogramming, Bd. 12, Nr. 2: S. 175-181
Reichenbach, Myriam; Lim, Tiongti; Reichenbach, Horst-Dieter; Güngör, Tuna; Habermann, Felix A.; Matthiesen, Marieke; Hofmann, Andreas; Weber, Frank; Zerbe, Holm; Grupp, Thomas; Sinowatz, Fred; Pfeifer, Alexander und Wolf, Eckhard
(2010):
Germ-line transmission of lentiviral PGK-EGFP integrants in transgenic cattle: new perspectives for experimental embryology.
In: Transgenic Research, Bd. 19, Nr. 4: S. 549-556
Grzech, Marjeta; Dahlhoff, Maik; Herbach, Nadja; Habermann, Felix A.; Renner-Müller, Ingrid; Wanke, Rüdiger; Flaswinkel, Heinrich; Wolf, Eckhard und Schneider, Marlon R.
(2010):
Specific transgene expression in mouse pancreatic beta-cells under the control of the porcine insulin promoter.
In: Molecular and cellular endocrinology, Bd. 315, Nr. 1-2: S. 219-224
2009
Noyes, Harry A.; Alimohammadian, Mohammad H.; Agaba, Morris; Brass, Andy; Fuchs, Helmut; Gailus-Durner, Valerie; Hulme, Helen; Iraqi, Fuad; Kemp, Stephen; Rathkolb, Birgit; Wolf, Eckhard; Hrabé de Angelis, Martin; Roshandel, Delnaz und Naessens, Jan
(2009):
Mechanisms controlling anaemia in Trypanosoma congolense infected mice.
In: PLOS ONE
4(4), e5170
[PDF, 1MB]
Pflanz, Heike; Vana, Karen; Mitteregger, Gerda; Renner-Müller, Ingrid; Pace, Claudia; Küchenhoff, Helmut ORCID: https://orcid.org/0000-0002-6372-2487; Kretzschmar, Hans A.; Wolf, Eckhard und Weiss, Stefan
(2009):
Scrapie-infected transgenic mice expressing a laminin receptor decoy mutant reveal a prolonged incubation time associated with low levels of prpres.
In: Journal of Molecular Biology, Bd. 388, Nr. 4: S. 721-729
Berendt, Frank J.; Fröhlich, Thomas; Bolbrinker, Patrick; Boelhauve, Marc; Güngör, Tuna; Habermann, Felix A.; Wolf, Eckhard und Arnold, Georg J.
(2009):
Highly sensitive saturation labeling reveals changes in abundance of cell cycle-associated proteins and redox enzyme variants during oocyte maturation in vitro.
In: Proteomics, Bd. 9, Nr. 3: S. 550-564
2008
Lisse, Thomas S.; Thiele, Frank; Fuchs, Helmut; Hans, Wolfgang; Przemeck, Gerhard K. H.; Abe, Koichiro; Rathkolb, Birgit; Quintanilla-Martinez, Leticia; Hoelzlwimmer, Gabriele; Helfrich, Miep; Wolf, Eckhard; Ralston, Stuart H. und Hrabé de Angelis, Martin
(Februar 2008):
ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta.
In: PLOS Genetics
4(2)
, S. 1-11
[PDF, 941kB]
Soeker, Torben; Dalke, Claudia; Puk, Oliver; Floss, Thomas; Becker, Lore; Bolle, Ines; Favor, Jack; Hans, Wolfgang; Hoelter, Sabine M.; Horsch, Marion; Kallnik, Magdalena; Kling, Eva; Moerth, Corinna; Schrewe, Anja; Stigloher, Christian; Topp, Stefanie; Gailus-Durner, Valerie; Naton, Beatrix; Beckers, Johannes; Fuchs, Helmut; Ivandic, Boris; Klopstock, Thomas; Schulz, Holger; Wolf, Eckhard; Wurst, Wolfgang; Bally-Cuif, Laure; de Angelis, Martin Hrabe und Graw, Jochen
(2008):
Pleiotropic effects in Eya3 knockout mice.
In: BMC Developmental Biology
8:118
[PDF, 3MB]
Lepikhov, Konstantin; Zakhartchenko, Valeri; Hao, R. u.; Yang, Feikun; Wrenzycki, Christine; Niemann, Heiner; Wolf, Eckhard und Walter, Joern
(2008):
Evidence for conserved DNA and histone H3 methylation reprogramming in mouse, bovine and rabbit zygotes.
In: Epigenetics & Chromatin
1:8
[PDF, 2MB]
2007
Wuensch, Annegret; Habermann, Felix A.; Kurosaka, Satoshi; Klose, Regina; Zakhartchenko, Valeri; Reichenbach, Horst-Dieter; Sinowatz, Fred; McLaughlin, K. J. und Wolf, Eckhard
(2007):
Quantitative monitoring of pluripotency gene activation after somatic cloning in cattle.
In: Biology of Reproduction, Bd. 76, Nr. 6: S. 983-991
[PDF, 409kB]
2001
Alessandrini, Francesca; Jakob, Thilo; Wolf, Alexander; Wolf, Eckhard; Balling, Rudolf; Hrabé de Angelis, Martin; Ring, Johannes und Behrendt, Heidrun
(2001):
ENU mouse mutagenesis: Generation of mouse mutants with aberrant plasma IgE levels.
In: International Archives of Allergy and Immunology, Nr. 1-3: S. 25-28
[PDF, 147kB]
2000
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