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Veröffentlichungsdatum
Anzahl der Publikationen: 106
2023
Mukhopadhyay, Tufan K. 
ORCID: https://orcid.org/0000-0001-8888-5373; Willems, Sabine ORCID: https://orcid.org/0000-0002-9755-3394; Arp, Christopher J. ORCID: https://orcid.org/0000-0002-5059-6178; Morstein, Johannes; Haake, Caleb T.; Merk, Daniel ORCID: https://orcid.org/0000-0002-5359-8128 und Trauner, Dirk ORCID: https://orcid.org/0000-0002-6782-6056
(2023):
Development of Light‐Activated LXR Agonists.
In: ChemMedChem, Bd. 18, Nr. 11
[PDF, 5MB]
ORCID: https://orcid.org/0000-0001-8888-5373; Willems, Sabine ORCID: https://orcid.org/0000-0002-9755-3394; Arp, Christopher J. ORCID: https://orcid.org/0000-0002-5059-6178; Morstein, Johannes; Haake, Caleb T.; Merk, Daniel ORCID: https://orcid.org/0000-0002-5359-8128 und Trauner, Dirk ORCID: https://orcid.org/0000-0002-6782-6056
(2023):
Development of Light‐Activated LXR Agonists.
In: ChemMedChem, Bd. 18, Nr. 11
[PDF, 5MB]
2022
Küllmer, Florian; Vepřek, Nynke A.; Borowiak, Malgorzata; Nasufović, Veselin; Barutzki, Sebastian; Thorn-Seshold, Oliver; Arndt, Hans-Dieter und Trauner, Dirk
(2022):
Next Generation Opto-Jasplakinolides Enable Local Remodeling of Actin Networks.
In: Angewandte Chemie International Edition, Bd. 61, Nr. 48, e202210220
Konrad, David B.; Ruehmann, Klaus-Peter; Ando, Hiroyasu; Hetzler, Belinda E.; Strassner, Nina; Houk, Kendall N.; Matsuura, Bryan S. und Trauner, Dirk
(2022):
A concise synthesis of tetrodotoxin.
In: Science, Bd. 377, Nr. 6604: S. 411-415
Impastato, Anna C.; Shemet, Andrej; Vepřek, Nynke A.; Saper, Gadiel; Hess, Henry; Rao, Lu; Gennerich, Arne und Trauner, Dirk
(2022):
Optical Control of Mitosis with a Photoswitchable Eg5 Inhibitor.
In: Angewandte Chemie International Edition, Bd. 61, Nr. 9, e202115846
Maier, Martin S.; Shemet, Andrej und Trauner, Dirk
(2022):
Assembling the carbon skeleton of A-74528.
In: Chemical Science, Bd. 13, Nr. 28: S. 8395-8400
Punia, Kamia; Britton, Dustin; Hull, Katharina; Yin, Liming; Wang, Yifei; Renfrew, P. Douglas; Gilchrist, M. Lane; Bonneau, Richard; Trauner, Dirk und Montclare, Jin K.
(2022):
Fluorescent azobenzene-confined coiled-coil mesofibers.
In: Soft Matter, Bd. 19, Nr. 3: S. 497-501
Pritzl, Stefanie D.; Morstein, Johannes; Kahler, Sophia; Konrad, David B.; Trauner, Dirk und Lohmüller, Theobald
(2022):
Postsynthetic Photocontrol of Giant Liposomes via Fusion-Based Photolipid Doping.
In: Langmuir, Bd. 38, Nr. 39: S. 11941-11949
2021
Donthamsetti, Prashant; Konrad, David B.; Hetzler, Belinda; Fu, Zhu; Trauner, Dirk und Isacoff, Ehud Y.
(2021):
Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor.
In: Journal of the American Chemical Society, Bd. 143, Nr. 24: S. 8951-8956
Donthamsetti, Prashant; Winter, Nils; Hoagland, Adam; Stanley, Cherise; Visel, Meike; Lammel, Stephan; Trauner, Dirk und Isacoff, Ehud
(2021):
Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors.
In: Nature Communications, Bd. 12, Nr. 1, 4775
Fischer, Christian; Veprek, Nynke A.; Peitsinis, Zisis; Ruhmann, Klaus-Peter; Yang, Chao; Spradlin, Jessica N.; Dovala, Dustin; Nomura, Daniel K.; Zhang, Yingkai und Trauner, Dirk
(2021):
De novo Design of SARS-CoV-2 Main Protease Inhibitors.
In: Synlett, Bd. 33, Nr. 5: S. 458-463
Huell, Katharina; Fernandez-Duenas, Victor; Schoenberger, Matthias; Lopez-Cano, Marc; Trauner, Dirk und Ciruela, Francisco
(2021):
Optical Control of Adenosine-Mediated Pain Modulation.
In: Bioconjugate Chemistry, Bd. 32, Nr. 9: S. 1979-1983
Morstein, Johannes; Kol, Matthijs; Novak, Alexander J. E.; Feng, Suihan; Khayyo, Shadi; Hinnah, Konstantin; Li-Purcell, Nasi; Pan, Grace; Williams, Benjamin M.; Riezman, Howard; Atilla-Gokcumen, G. Ekin; Holthuis, Joost C. M. und Trauner, Dirk
(2021):
Short Photoswitchable Ceramides Enable Optical Control of Apoptosis.
In: ACS Chemical Biology, Bd. 16, Nr. 3: S. 452-456
Pritzl, Stefanie D.; Konrad, David B.; Ober, Martina F.; Richter, Alexander F.; Frank, James A.; Nickel, Bert; Trauner, Dirk und Lohmüller, Theobald
(2021):
Optical Membrane Control with Red Light Enabled by Red-Shifted Photolipids.
In: Langmuir, Bd. 38, Nr. 1: S. 385-393
Reynders, Martin; Chaikuad, Apirat; Berger, Benedict-Tilman; Bauer, Katharina; Koch, Pierre; Laufer, Stefan; Knapp, Stefan und Trauner, Dirk
(2021):
Controlling the Covalent Reactivity of a Kinase Inhibitor with Light.
In: Angewandte Chemie-International Edition, Bd. 60, Nr. 37: S. 20178-20183
Reynders, Martin und Trauner, Dirk
(2021):
Optical control of targeted protein degradation.
In: Cell Chemical Biology, Bd. 28, Nr. 7: S. 969-986
2020
Konrad, David B.; Savasci, Gökcen; Allmendinger, Lars; Trauner, Dirk; Ochsenfeld, Christian ORCID: https://orcid.org/0000-0002-4189-6558 und Ali, Ahmed M.
(2020):
Computational Design and Synthesis of a Deeply Red-Shifted and Bistable Azobenzene.
In: Journal of the American Chemical Society, Bd. 142, Nr. 14: S. 6538-6547
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-4189-6558 und Ali, Ahmed M.
(2020):
Computational Design and Synthesis of a Deeply Red-Shifted and Bistable Azobenzene.
In: Journal of the American Chemical Society, Bd. 142, Nr. 14: S. 6538-6547
[PDF, 2MB]
Müller-Deku, Adrian; Meiring, Joyce C. M.; Loy, Kristina; Kraus, Yvonne; Heise, Constanze; Bingham, Rebekkah; Jansen, Klara I.; Qu, Xiaoyi; Bartolini, Francesca; Kapitein, Lukas C.; Akhmanova, Anna; Ahlfeld, Julia; Trauner, Dirk und Thorn-Seshold, Oliver
(2020):
Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton.
In: Nature communications, Bd. 11, Nr. 1, 4640
[PDF, 7MB]
Kopf, Aglaja; Renkawitz, Jörg; Hauschild, Robert; Girkontaite, Irute; Tedford, Kerry; Merrin, Jack; Thorn-Seshold, Oliver; Trauner, Dirk; Haecker, Hans; Fischer, Klaus-Dieter; Kiermaier, Eva und Sixt, Michael
(2020):
Microtubules control cellular shape and coherence in amoeboid migrating cells.
In: Journal of Cell Biology, Bd. 219, Nr. 6, e201907154
Urban, Patrick; Pritzl, Stefanie D.; Ober, Martina F.; Dirscherl, Christina F.; Pernpeintner, Carla; Konrad, David B.; Frank, James A.; Trauner, Dirk; Nickel, Bert und Lohmueller, Theobald
(2020):
A Lipid Photoswitch Controls Fluidity in Supported Bilayer Membranes.
In: Langmuir, Bd. 36, Nr. 10: S. 2629-2634
Borowiak, Malgorzata; Kuellmer, Florian; Gegenfurtner, Florian; Peil, Sebastian; Nasufovic, Veselin; Zahler, Stefan; Thorn-Seshold, Oliver; Trauner, Dirk und Arndt, Hans-Dieter
(2020):
Optical Manipulation of F-Actin with Photoswitchable Small Molecules.
In: Journal of the American Chemical Society, Bd. 142, Nr. 20: S. 9240-9249
Scheidt, Holger A.; Kolocaj, Katja; Konrad, David B.; Frank, James A.; Trauner, Dirk; Langosch, Dieter und Huster, Daniel
(2020):
Light-induced lipid mixing implies a causal role of lipid splay in membrane fusion.
In: Biochimica et Biophysica Acta-Biomembranes, Bd. 1862, Nr. 11, 183438
Hinnah, Konstantin; Willems, Sabine; Morstein, Johannes; Heering, Jan; Hartrampf, Felix W. W.; Broichhagen, Johannes; Leippe, Philipp; Merk, Daniel und Trauner, Dirk
(2020):
Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor gamma (PPAR gamma).
In: Journal of Medicinal Chemistry, Bd. 63, Nr. 19: S. 10908-10920
Quintela-Varela, Hugo; Jamieson, Cooper S.; Shao, Qianzhen; Houk, K. N. und Trauner, Dirk
(2020):
Bioinspired Synthesis of (-)-PF-1018.
In: Angewandte Chemie-International Edition, Bd. 59, Nr. 13: S. 5263-5267
Leippe, Philipp; Broichhagen, Johannes; Cailliau, Katia; Mougel, Alexandra; Morel, Marion; Dissous, Colette; Trauner, Dirk und Vicogne, Jerome
(2020):
Transformation of Receptor Tyrosine Kinases into Glutamate Receptors and Photoreceptors.
In: Angewandte Chemie-International Edition, Bd. 59, Nr. 17: S. 6720-6723
Hartrampf, Nina; Seki, Toshiyuki; Baumann, Andreas; Watson, Philip; Veprek, Nynke A.; Hetzler, Belinda E.; Hoffmann-Roder, Anja; Tsuji, Moriya und Trauner, Dirk
(2020):
Optical Control of Cytokine Production Using Photoswitchable Galactosylceramides.
In: Chemistry-A European Journal, Bd. 26, Nr. 20: S. 4476-4479
Pritzl, Stefanie D.; Urban, Patrick; Prasselsperger, Alexander; Konrad, David B.; Frank, James A.; Trauner, Dirk und Lohmueller, Theobald
(2020):
Photolipid Bilayer Permeability is Controlled by Transient Pore Formation.
In: Langmuir, Bd. 36, Nr. 45: S. 13509-13515
Reynders, Martin; Matsuura, Bryan S.; Berouti, Marleen; Simoneschi, Daniele; Marzio, Antonio; Pagano, Michele und Trauner, Dirk
(2020):
PHOTACs enable optical control of protein degradation.
In: Science Advances, Bd. 6, Nr. 8, eaay5064
Morstein, Johannes; Trads, Julie B.; Hinnah, Konstantin; Willems, Sabine; Barber, David M.; Trauner, Michael; Merk, Daniel und Trauner, Dirk
(2020):
Optical control of the nuclear bile acid receptor FXR with a photohormone.
In: Chemical Science, Bd. 11, Nr. 2: S. 429-434
2019
Maier, Martin S.; Huell, Katharina; Reynders, Martin; Matsuura, Bryan S.; Leippe, Philipp; Ko, Tongil; Schaeffer, Lukas und Trauner, Dirk
(2019):
Oxidative Approach Enables Efficient Access to Cyclic Azobenzenes.
In: Journal of the American Chemical Society, Bd. 141, Nr. 43: S. 17295-17304
Huell, Katharina; Benster, Tyler; Manookin, Michael B.; Trauner, Dirk; Van Gelder, Russell N. und Laprell, Laura
(2019):
Photopharmacologic Vision Restoration Reduces Pathological Rhythmic Field Potentials in Blind Mouse Retina.
In: Scientific Reports, Bd. 9, 13561
[PDF, 9MB]
Trads, Julie B.; Huell, Katharina; Matsuura, Bryan S.; Laprell, Laura; Fehrentz, Timm; Gorldt, Nicole; Kozek, Krystian A.; Weaver, C. David; Klocker, Nikolaj; Barber, David M. und Trauner, Dirk
(2019):
Sign Inversion in Photopharmacology: Incorporation of Cyclic Azobenzenes in Photoswitchable Potassium Channel Blockers and Openers.
In: Angewandte Chemie-International Edition, Bd. 58, Nr. 43: S. 15421-15428
Winter, Nils; Rupcic, Zeljka; Stadler, Marc und Trauner, Dirk
(2019):
Synthesis and biological evaluation of (+/-)-hippolachnin and analogs.
In: Journal of Antibiotics, Bd. 72, Nr. 6: S. 375-383
Morstein, Johannes; Hill, Rose Z.; Novak, Alexander J. E.; Feng, Suihan; Norman, Derek D.; Donthamsetti, Prashant C.; Frank, James A.; Harayama, Takeshi; Williams, Benjamin M.; Parrill, Abby L.; Tigyi, Gabor J.; Riezman, Howard; Isacoff, Ehud Y.; Bautista, Diana M. und Trauner, Dirk
(2019):
Optical control of sphingosine-1-phosphate formation and function.
In: Nature Chemical Biology, Bd. 15, Nr. 6
Kol, Matthijs; Williams, Ben; Toombs-Ruane, Henry; Franquelim, Henri G.; Korneev, Sergei; Schroeer, Christian; Schwille, Petra; Trauner, Dirk; Holthuis, Joost C. M. und Frank, James A.
(2019):
Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides.
In: eLife, Bd. 8, e43230
[PDF, 5MB]
Rizzo, Antonio; Mayer, Robert J. und Trauner, Dirk
(2019):
Biomimetic Approach Toward Enterocin and Deoxyenterocin.
In: Journal of Organic Chemistry, Bd. 84, Nr. 3: S. 1162-1175
Konrad, David B.; Kicin, Bilal und Trauner, Dirk
(2019):
Concise Asymmetric Synthesis of Kweichowenol A.
In: Synlett, Bd. 30, Nr. 4: S. 383-386
Winter, Nils und Trauner, Dirk
(2019):
Synthesis of acremines A, B and F and studies on the bisacremines.
In: Beilstein Journal of Organic Chemistry, Bd. 15: S. 2271-2276
2018
Haefner, Stephanie; Burg, Finn; Kannler, Martina; Urban, Nicole; Mayer, Peter; Dietrich, Alexander; Trauner, Dirk; Broichhagen, Johannes und Schaefer, Michael
(2018):
A (+)-Larixol Congener with High Affinity and Subtype Selectivity toward TRPC6.
In: Chemmedchem, Bd. 13, Nr. 10: S. 1028-1035
Leinders-Zufall, Trese; Storch, Ursula; Bleymehl, Katherin; Mederos y Schnitzler, Michael; Frank, James A.; Konrad, David B.; Trauner, Dirk; Gudermann, Thomas und Zufall, Frank
(2018):
PhoDAGs Enable Optical Control of Diacylglycerol-Sensitive Transient Receptor Potential Channels.
In: Cell Chemical Biology, Bd. 25, Nr. 2: S. 215-223
Urban, Patrick; Pritzl, Stefanie D.; Konrad, David B.; Frank, James A.; Pernpeintner, Carla; Roeske, Christian R.; Trauner, Dirk und Lohmüller, Theobald
(2018):
Light-Controlled Lipid Interaction and Membrane Organization in Photolipid Bilayer Vesicles.
In: Langmuir, Bd. 34, Nr. 44: S. 13368-13374
Leippe, Philipp; Winter, Nils; Sumser, Martin P. und Trauner, Dirk
(2018):
Optical Control of a Delayed Rectifier and a Two-Pore Potassium Channel with a Photoswitchable Bupivacaine.
In: ACS Chemical Neuroscience, Bd. 9, Nr. 12: S. 2886-2891
Rizzo, Antonio und Trauner, Dirk
(2018):
Toward (-)-Enterocin: An Improved Cuprate Barbier Protocol To Overcome Strain and Sterical Hindrance.
In: Organic Letters, Bd. 20, Nr. 7: S. 1841-1844
Podewin, Tom; Ast, Julia; Broichhagen, Johannes; Fine, Nicholas H. F.; Nasteska, Daniela; Leippe, Philipp; Gailer, Manuel; Buenaventura, Teresa; Kanda, Nisha; Jones, Ben J.; M'Kadmi, Celine; Baneres, Jean-Louis; Marie, Jacky; Tomas, Alejandra; Trauner, Dirk; Hoffmann-Röder, Anja und Hodson, David J.
(2018):
Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology.
In: ACS Central Science, Bd. 4, Nr. 2: S. 166-179
[PDF, 6MB]
Eisel, Bianca; Hartrampf, Felix W. W.; Meier, Thomas und Trauner, Dirk
(2018):
Reversible optical control of F1Fo-ATP synthase using photoswitchable inhibitors.
In: Febs Letters, Bd. 592, Nr. 3: S. 343-355
Williams, Benjamin M. und Trauner, Dirk
(2018):
Azomethine Ylide Cycloaddition Approach toward Dendrobine: Synthesis of 5-Deoxymubironine C.
In: Journal of Organic Chemistry, Bd. 83, Nr. 6: S. 3061-3068
Reyes, Julius R.; Winter, Nils; Spessert, Lukas und Trauner, Dirk
(2018):
Biomimetic Synthesis of (+)-Aspergillin PZ.
In: Angewandte Chemie-International Edition, Bd. 57, Nr. 47: S. 15587-15591
Glock, Philipp; Broichhagen, Johannes; Kretschmer, Simon; Blumhardt, Philipp; Mücksch, Jonas; Trauner, Dirk und Schwille, Petra
(2018):
Optical Control of a Biological Reaction-Diffusion System.
In: Angewandte Chemie-International Edition, Bd. 57, Nr. 9: S. 2362-2366
Terwilliger, Daniel W. und Trauner, Dirk
(2018):
Selective Synthesis of Divergolide I.
In: Journal of the American Chemical Society, Bd. 140, Nr. 8: S. 2748-2751
Farrants, Helen; Gutzeit, Vanessa A.; Acosta-Ruiz, Amanda; Trauner, Dirk; Johnsson, Kai; Levitz, Joshua und Broichhagen, Johannes
(2018):
SNAP-Tagged Nanobodies Enable Reversible Optical Control of a G Protein-Coupled Receptor via a Remotely Tethered Photoswitchable Ligand.
In: ACS Chemical Biology, Bd. 13, Nr. 9: S. 2682-2688
Hartrampf, Nina; Winter, Nils; Pupo, Gabriele; Stoltz, Brian M. und Trauner, Dirk
(2018):
Total Synthesis of the Norhasubanan Alkaloid Stephadiamine.
In: Journal of the American Chemical Society, Bd. 140, Nr. 28: S. 8675-8680
Fehrentz, Timm; Huber, Florian M. E.; Hartrampf, Nina; Bruegmann, Tobias; Frank, James A.; Fine, Nicholas H. F.; Malan, Daniela; Danzl, Johann G.; Tikhonov, Denis B.; Sumser, Martin; Sasse, Philipp; Hodson, David J.; Zhorov, Boris S.; Klocker, Nikolaj und Trauner, Dirk
(2018):
Optical control of L-type Ca2+ channels using a diltiazem photoswitch.
In: Nature Chemical Biology, Bd. 14, Nr. 8: S. 764-767
DuBay, Kateri H.; Iwan, Katharina; Osorio-Planes, Laura; Geissler, Phillip L.; Groll, Michael; Trauner, Dirk und Broichhagen, Johannes
(2018):
A Predictive Approach for the Optical Control of Carbonic Anhydrase II Activity.
In: ACS Chemical Biology, Bd. 13, Nr. 3: S. 793-800
2017
Barber, David M.; Liu, Shu-An; Gottschling, Kevin; Sumser, Martin; Hollmann, Michael und Trauner, Dirk
(2017):
Optical control of AMPA receptors using
a photoswitchable quinoxaline-2,3-dione
antagonist.
In: Chemical Science, Bd. 8, Nr. 1: S. 611-615
[PDF, 564kB]
Pernpeintner, Carla; Frank, James A.; Urban, Patrick; Röske, Christian R.; Pritzl, Stefanie D.; Trauner, Dirk und Lohmüller, Theobald
(2017):
Light-Controlled Membrane Mechanics and Shape Transitions of Photoswitchable Lipid Vesicles.
In: Langmuir, Bd. 33, Nr. 16: S. 4083-4089
Cheng, Bichu; Shchepakin, Denis; Kavanaugh, Michael P. und Trauner, Dirk
(2017):
Photoswitchable Inhibitor of a Glutamate Transporter.
In: ACS Chemical Neuroscience, Bd. 8, Nr. 8: S. 1668-1672
Cheng, Bichu; Müller, Rolf und Trauner, Dirk
(2017):
Total Syntheses of Cystobactamids and Structural Confirmation of Cystobactamid 919-2.
In: Angewandte Chemie-international Edition, Bd. 56, Nr. 41: S. 12755-12759
Liu, Shu-An und Trauner, Dirk
(2017):
Asymmetric Synthesis of the Antiviral Diterpene Wickerol A.
In: Journal of the American Chemical Society, Bd. 139, Nr. 28: S. 9491-9494
Berry, Michael H.; Holt, Amy; Levitz, Joshua; Broichhagen, Johannes; Gaub, Benjamin M.; Visel, Meike; Stanley, Cherise; Aghi, Krishan; Kim, Yang Joon; Trauner, Dirk; Flannery, John und Isacoff, Ehud Y.
(2017):
Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor.
In: Nature Communications, Bd. 8, 1862
[PDF, 2MB]
Frank, James Allen; Yushchenko, Dmytro A.; Fine, Nicholas H. F.; Duca, Margherita; Citir, Mevlut; Broichhagen, Johannes; Hodson, David J.; Schultz, Carsten und Trauner, Dirk
(2017):
Optical control of GPR40 signalling in pancreatic beta-cells.
In: Chemical Science, Bd. 8, Nr. 11: S. 7604-7610
Bihelovic, Filip; Stichnoth, Desiree; Surup, Frank; Müller, Rolf und Trauner, Dirk
(2017):
Total Synthesis of CrocaginA.
In: Angewandte Chemie-international Edition, Bd. 56, Nr. 42: S. 12848-12851
Leippe, Philipp; Leman, Julia Köhler und Trauner, Dirk
(2017):
Specificity and Speed: Tethered Photopharmacology.
In: Biochemistry, Bd. 56, Nr. 39: S. 5214-5220
Winter, Nils und Trauner, Dirk
(2017):
Thiocarbonyl Ylide Chemistry Enables a Concise Synthesis of (+/-)-Hippolachnin A.
In: Journal of the American Chemical Society, Bd. 139, Nr. 34: S. 11706-11709
Hartrampf, Felix W. W. und Trauner, Dirk
(2017):
Total Synthesis of Lycopladine A and Carinatine A via a Base-Mediated Carbocyclization.
In: Journal of Organic Chemistry, Bd. 82, Nr. 15: S. 8206-8212
Viehrig, Konrad; Surup, Frank; Volz, Carsten; Herrmann, Jennifer; Abou Fayad, Antoine; Adam, Sebastian; Köhnke, Jesko; Trauner, Dirk und Müller, Rolf
(2017):
Structure and Biosynthesis of Crocagins: Polycyclic Posttranslationally Modified Ribosomal Peptides from Chondromyces crocatus.
In: Angewandte Chemie-international Edition, Bd. 56, Nr. 26: S. 7407-7410
Podewin, Tom; Broichhagen, Johannes; Frost, Christina; Groneberg, Dieter; Ast, Julia; Meyer-Berg, Helena; Fine, Nicholas H. F.; Friebe, Andreas; Zacharias, Martin; Hodson, David J.; Trauner, Dirk und Hoffmann-Röder, Anja
(2017):
Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone.
In: Chemical Science, Bd. 8, Nr. 6: S. 4644-4653
Ketels, Marthe; Konrad, David B.; Karaghiosoff, Konstantin; Trauner, Dirk und Knochel, Paul
(2017):
Selective Lithiation, Magnesiation, and Zincation of Unsymmetrical Azobenzenes Using Continuous Flow.
In: Organic Letters, Bd. 19, Nr. 7: S. 1666-1669
Hao, Hong-Dong und Trauner, Dirk
(2017):
Furans as Versatile Synthons: Total Syntheses of Caribenol A and Caribenol B.
In: Journal of the American Chemical Society, Bd. 139, Nr. 11: S. 4117-4122
Schmid, Matthias und Trauner, Dirk
(2017):
Biomimetic Synthesis of Complex Flavonoids Isolated from Daemonorops "Dragon's Blood".
In: Angewandte Chemie-international Edition, Bd. 56, Nr. 40: S. 12332-12335
Hartrampf, Felix W. W.; Barber, David M.; Gottschling, Kevin; Leippe, Philipp; Hollmann, Michael und Trauner, Dirk
(2017):
Development of a photoswitchable antagonist of NMDA receptors.
In: Tetrahedron, Bd. 73, Nr. 33: S. 4905-4912
Eguchi, Kohgaku; Taoufiq, Zacharie; Thorn-Seshold, Oliver; Trauner, Dirk; Hasegawa, Masato und Takahashi, Tomoyuki
(2017):
Wild-Type Monomeric alpha-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held.
In: Journal of Neuroscience, Bd. 37, Nr. 25: S. 6043-6052
Levitz, Joshua; Broichhagen, Johannes; Leippe, Philipp; Konrad, David; Trauner, Dirk und Isacoff, Ehud Y.
(2017):
Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 114, Nr. 17, E3546-E3554
Mehta, Zenobia B.; Johnston, Natalie R.; Nguyen-Tu, Marie-Sophie; Broichhagen, Johannes; Schultz, Peter; Larner, Dean P.; Leclerc, Isabelle; Trauner, Dirk; Rutter, Guy A. und Hodson, David J.
(2017):
Remote control of glucose homeostasis in vivo using photopharmacology.
In: Scientific Reports, Bd. 7, 291
[PDF, 4MB]
Laprell, Laura; Tochitsky, Ivan; Kaur, Kuldeep; Manookin, Michael B.; Stein, Marco; Barber, David M.; Schön, Christian; Michalakis, Stylianos; Biel, Martin; Kramer, Richard H.; Sumser, Martin P.; Trauner, Dirk und Gelder, Russell N. van
(2017):
Photopharmacological control of bipolar cells restores visual function in blind mice.
In: Journal of Clinical investigation, Bd. 127, Nr. 7: S. 2598-2611
Matsuura, Bryan S.; Kölle, Patrick; Trauner, Dirk; Vivie-Riedle, Regina de und Meier, Robin
(2017):
Unravelling Photochemical Relationships Among Natural Products from Aplysia dactylomela.
In: ACS Central Science, Bd. 3, Nr. 1: S. 39-46
Hartrampf, Felix W. W.; Furukawa, Takayuki und Trauner, Dirk
(2017):
AConia-Ene-Type Cyclization under Basic Conditions Enables an Efficient Synthesis of (-)-Lycoposerramine R.
In: Angewandte Chemie-international Edition, Bd. 56, Nr. 3: S. 893-896
Volpin, Giulio; Vepřek, Nynke A.; Bellan, Andreas B. und Trauner, Dirk
(2017):
Enantioselective Synthesis and Racemization of (-)-Sinoracutine.
In: Angewandte Chemie-international Edition, Bd. 56, Nr. 3: S. 897-901
Trads, Julie B.; Burgstaller, Jessica; Laprell, Laura; Konrad, David B.; Osa de la Rosa, Luis de la; Weaver, C. David; Baier, Herwig; Trauner, Dirk und Barber, David M.
(2017):
Optical control of GIRK channels using visible light.
In: Organic & Biomolecular Chemistry, Bd. 15, Nr. 1: S. 76-81
2016
Hager, Anastasia; Vrielink, Nina; Hager, Dominik; Lefranc, Julien und Trauner, Dirk
(2016):
Synthetic approaches towards alkaloids bearing α-tertiary amines.
In: Natural Product Reports, Bd. 33, Nr. 3: S. 491-522
[PDF, 8MB]
Broichhagen, Johannes; Klingl, Yvonne E.; Trauner, Dirk und Mayer, Peter
(2016):
6-[6-(Pyridin-2-yl)-1,2,4,5-tetrazin-3-yl] pyridin-3-amine monohydrate.
In: Acta Crystallographica Section E-Crystallographic Communications, Bd. 72:
238-+
[PDF, 688kB]
Schell, Ursula; Simon, Sylvia; Sahr, Tobias; Hager, Dominik; Albers, Michael F.; Kessler, Aline; Fahrnbauer, Felix; Trauner, Dirk; Hedberg, Christian; Buchrieser, Carmen und Hilbi, Hubert
(2016):
The α-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signalling and gene expression of Legionella pneumophila.
In: Molecular Microbiology, Bd. 99, Nr. 4: S. 778-793
Frank, James Allen; Franquelim, Henri G.; Schwille, Petra und Trauner, Dirk
(2016):
Optical Control of Lipid Rafts with Photoswitchable Ceramides.
In: Journal of the American Chemical Society, Bd. 138, Nr. 39: S. 12981-12986
Trauner, Dirk
(2016):
Controlling Biological Pathways with Photopharmacology.
In: Biophysical Journal, Bd. 110, Nr. 3:
364A-364A
Johnston, Natalie R.; Mitchell, Ryan K.; Haythorne, Elizabeth; Pessoa, Maria Paiva; Semplici, Francesca; Ferrer, Jorge; Piemonti, Lorenzo; Marchetti, Piero; Bugliani, Marco; Bosco, Domenico; Berishvili, Ekaterine; Duncanson, Philip; Watkinson, Michael; Broichhagen, Johannes; Trauner, Dirk; Rutter, Guy A. und Hodson, David J.
(2016):
Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose.
In: Cell Metabolism, Bd. 24, Nr. 3: S. 389-401
Konrad, David B.; Frank, James A. und Trauner, Dirk
(2016):
Synthesis of Redshifted Azobenzene Photoswitches by Late-Stage Functionalization.
In: Chemistry-A European Journal, Bd. 22, Nr. 13: S. 4364-4368
Frank, James Allen; Yushchenko, Dmytro A.; Hodson, David J.; Lipstein, Noa; Nagpal, Jatin; Rutter, Guy A.; Rhee, Jeong-Seop; Gottschalk, Alexander; Brose, Nils; Schultz, Carsten und Trauner, Dirk
(2016):
Photoswitchable diacylglycerols enable optical control of protein kinase C.
In: Nature Chemical Biology, Bd. 12, Nr. 9: S. 755-762
Williams, Benjamin M. und Trauner, Dirk
(2016):
Expedient Synthesis of (+)-Lycopalhine A.
In: Angewandte Chemie-international Edition, Bd. 55, Nr. 6: S. 2191-2194
Broichhagen, Johannes; Johnston, Natalie R.; Ohlen, Yorrick von; Meyer-Berg, Helena; Jones, Ben J.; Bloom, Stephen R.; Rutter, Guy A.; Trauner, Dirk und Hodson, David J.
(2016):
Allosteric Optical Control of a Class B G-Protein-Coupled Receptor.
In: Angewandte Chemie-international Edition, Bd. 55, Nr. 19: S. 5865-5868
Barber, David M.; Schönberger, Matthias; Burgstaller, Jessica; Levitz, Joshua; Weaver, C. David; Isacoff, Ehud Y.; Baier, Herwig und Trauner, Dirk
(2016):
Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO).
In: Chemical Science, Bd. 7, Nr. 3: S. 2347-2352
2015
Simon, Sylvia; Schell, Ursula; Heuer, Natalie; Hager, Dominik; Albers, Michael F.; Matthias, Jan; Fahrnbauer, Felix; Trauner, Dirk; Eichinger, Ludwig; Hedberg, Christian und Hilbi, Hubert
(2015):
Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway.
In: PLOS Pathogens 11(12), e1005307 [PDF, 6MB]
In: PLOS Pathogens 11(12), e1005307 [PDF, 6MB]
Broichhagen, Johannes; Damijonaitis, Arunas; Levitz, Joshua; Sokol, Kevin R.; Leippe, Philipp; Konrad, David; Isacoff, Ehud Y. und Trauner, Dirk
(2015):
Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand.
In: ACS Central Science, Bd. 1, Nr. 7: S. 383-393
Guo, Yanan; Wolter, Tino; Kubar, Tomas; Sumser, Martin; Trauner, Dirk und Elstner, Marcus
(2015):
Molecular Dynamics Investigation of gluazo, a Photo-Switchable Ligand for the Glutamate Receptor GluK2.
In: PLOS ONE 10(8), e0135399 [PDF, 3MB]
In: PLOS ONE 10(8), e0135399 [PDF, 3MB]
Laprell, Laura; Repak, Emilienne; Franckevicius, Vilius; Hartrampf, Felix; Terhag, Jan; Hollmann, Michael; Sumser, Martin; Rebola, Nelson; DiGregorio, David A. und Trauner, Dirk
(2015):
Optical control of NMDA receptors with a diffusible photoswitch.
In: Nature Communications, Bd. 6, 8076
[PDF, 2MB]
Runtsch, Leander Simon; Barber, David Michael; Mayer, Peter; Groll, Michael; Trauner, Dirk und Broichhagen, Johannes
(2015):
Azobenzene-based inhibitors of human carbonic anhydrase II.
In: Beilstein Journal of Organic Chemistry, Bd. 11: S. 1129-1135
[PDF, 2MB]
Broichhagen, Johannes; Woodmansee, David H.; Trauner, Dirk und Mayer, Peter
(2015):
Crystal structure of (E)-1, 2-bis(4-bromo-2, 6-difluorophenyl)diazene.
In: Acta Crystallographica Section E-Crystallographic Communications, Bd. 71:
O459-+
Frank, James Allen; Moroni, Mirko; Moshourab, Rabih; Sumser, Martin; Lewin, Gary R. und Trauner, Dirk
(2015):
Photoswitchable fatty acids enable optical control of TRPV1.
In: Nature Communications, Bd. 6, 7118
[PDF, 1MB]
Broichhagen, Johannes; Frank, J. A.; Johnston, N. R.; Mitchell, R. K.; Šmid, K.; Marchetti, P.; Bugliani, M.; Rutter, Guy A.; Trauner, Dirk und Hodson, David J.
(2015):
A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function.
In: Chemical Communications, Bd. 51, Nr. 27: S. 6018-6021
[PDF, 5MB]
2014
Rullo, A.; Reiner, A.; Reiter, Alwin; Trauner, Dirk; Isacoff, E. Y. und Woolley, G. A.
(6. Oktober 2014):
Long wavelength optical control of glutamate receptor ion channels using a tetra-ortho-substituted azobenzene derivative.
In: Chemical Communications, Bd. 50, Nr. 93: S. 14613-14615
[PDF, 1MB]
Trauner, Dirk
(5. März 2014):
Finding function and form.
In: Natural Product Reports, Bd. 31, Nr. 4: S. 411-413
[PDF, 318kB]
Stichnoth, Desiree; Kölle, Patrick; Kimbrough, Thomas J.; Riedle, Eberhard ORCID: https://orcid.org/0000-0002-2672-5718; Vivie-Riedle, Regina de und Trauner, Dirk
(2014):
Photochemical formation of intricarene.
In: Nature Communications, Bd. 5, 5597
[PDF, 822kB]
ORCID: https://orcid.org/0000-0002-2672-5718; Vivie-Riedle, Regina de und Trauner, Dirk
(2014):
Photochemical formation of intricarene.
In: Nature Communications, Bd. 5, 5597
[PDF, 822kB]
Broichhagen, Johannes; Schönberger, Matthias; Cork, Simon C.; Frank, James A.; Marchetti, Piero; Bugliani, Marco; Shapiro, A. M. James; Trapp, Stefan; Rutter, Guy A.; Hodson, David J. und Trauner, Dirk
(2014):
Optical control of insulin release using a photoswitchable sulfonylurea.
In: Nature Communications, Bd. 5, 5116
[PDF, 3MB]
Carta, Valentina; Pangerl, Michael; Baur, Roland; Puthenkalam, Roshan; Ernst, Margot; Trauner, Dirk und Sigel, Erwin
(2014):
A Pentasymmetric Open Channel Blocker for Cys-Loop Receptor Channels.
In: PLOS ONE 9(9), e106688 [PDF, 1MB]
In: PLOS ONE 9(9), e106688 [PDF, 1MB]
Wolter, Tino; Steinbrecher, Thomas; Trauner, Dirk und Elstner, Marcus
(2014):
Ligand Photo-Isomerization Triggers Conformational Changes in iGluR2 Ligand Binding Domain.
In: PLOS ONE 9(4), e92716 [PDF, 5MB]
In: PLOS ONE 9(4), e92716 [PDF, 5MB]
2013
Olbrich, Martin; Mayer, Peter und Trauner, Dirk
(31. Oktober 2013):
A step toward polytwistane: synthesis and characterization of C-2-symmetric tritwistane.
In: Organic & Biomolecular Chemistry, Bd. 12, Nr. 1: S. 108-112
[PDF, 1MB]
Izquierdo-Serra, Merce; Trauner, Dirk; Llobet, Artur und Gorostiza, Pau
(2013):
Optical modulation of neurotransmission using calcium photocurrents through the ion channel LiGluR.
In: Frontiers in Molecular Neuroscience, Bd. 6, 3
[PDF, 1MB]
2012
Hog, Daniel T.; Webster, Robert und Trauner, Dirk
(2012):
Synthetic approaches toward sesterterpenoids.
In: Natural Product Reports, Bd. 29, Nr. 7: S. 752-779
[PDF, 870kB]
2010
Abrams, Ze'ev R.; Warrier, Ajithkumar; Trauner, Dirk und Zhang, Xiang
(Mai 2010):
A signal processing analysis of Purkinje cells in vitro.
In: Frontiers in Neural Circuits, Bd. 4, 13
[PDF, 1MB]