Anzahl der Publikationen: 107
Zeitschriftenartikel
Zhang, Jinhua; Schuknecht, Francis; Habermann, Ludwig; Pattis, Alexander; Heine, Jonathan; Pritzl, Stefanie D.; Trauner, Dirk und Lohmüller, Theobald ORCID: https://orcid.org/0000-0003-2699-7067
(2024):
Label‐Free Time‐Resolved Monitoring of Photolipid Bilayer Isomerization by Plasmonic Sensing.
In: Advanced Optical Materials, Bd. 12, Nr. 10
[PDF, 1MB]
Mukhopadhyay, Tufan K. ORCID: https://orcid.org/0000-0001-8888-5373; Willems, Sabine ORCID: https://orcid.org/0000-0002-9755-3394; Arp, Christopher J. ORCID: https://orcid.org/0000-0002-5059-6178; Morstein, Johannes; Haake, Caleb T.; Merk, Daniel ORCID: https://orcid.org/0000-0002-5359-8128 und Trauner, Dirk ORCID: https://orcid.org/0000-0002-6782-6056
(2023):
Development of Light‐Activated LXR Agonists.
In: ChemMedChem, Bd. 18, Nr. 11
[PDF, 5MB]
Küllmer, Florian; Vepřek, Nynke A.; Borowiak, Malgorzata; Nasufović, Veselin; Barutzki, Sebastian; Thorn-Seshold, Oliver; Arndt, Hans-Dieter und Trauner, Dirk
(2022):
Next Generation Opto-Jasplakinolides Enable Local Remodeling of Actin Networks.
In: Angewandte Chemie International Edition, Bd. 61, Nr. 48, e202210220
Konrad, David B.; Ruehmann, Klaus-Peter; Ando, Hiroyasu; Hetzler, Belinda E.; Strassner, Nina; Houk, Kendall N.; Matsuura, Bryan S. und Trauner, Dirk
(2022):
A concise synthesis of tetrodotoxin.
In: Science, Bd. 377, Nr. 6604: S. 411-415
Impastato, Anna C.; Shemet, Andrej; Vepřek, Nynke A.; Saper, Gadiel; Hess, Henry; Rao, Lu; Gennerich, Arne und Trauner, Dirk
(2022):
Optical Control of Mitosis with a Photoswitchable Eg5 Inhibitor.
In: Angewandte Chemie International Edition, Bd. 61, Nr. 9, e202115846
Punia, Kamia; Britton, Dustin; Hull, Katharina; Yin, Liming; Wang, Yifei; Renfrew, P. Douglas; Gilchrist, M. Lane; Bonneau, Richard; Trauner, Dirk und Montclare, Jin K.
(2022):
Fluorescent azobenzene-confined coiled-coil mesofibers.
In: Soft Matter, Bd. 19, Nr. 3: S. 497-501
Donthamsetti, Prashant; Winter, Nils; Hoagland, Adam; Stanley, Cherise; Visel, Meike; Lammel, Stephan; Trauner, Dirk und Isacoff, Ehud
(2021):
Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors.
In: Nature Communications, Bd. 12, Nr. 1, 4775
Fischer, Christian; Veprek, Nynke A.; Peitsinis, Zisis; Ruhmann, Klaus-Peter; Yang, Chao; Spradlin, Jessica N.; Dovala, Dustin; Nomura, Daniel K.; Zhang, Yingkai und Trauner, Dirk
(2021):
De novo Design of SARS-CoV-2 Main Protease Inhibitors.
In: Synlett, Bd. 33, Nr. 5: S. 458-463
Morstein, Johannes; Kol, Matthijs; Novak, Alexander J. E.; Feng, Suihan; Khayyo, Shadi; Hinnah, Konstantin; Li-Purcell, Nasi; Pan, Grace; Williams, Benjamin M.; Riezman, Howard; Atilla-Gokcumen, G. Ekin; Holthuis, Joost C. M. und Trauner, Dirk
(2021):
Short Photoswitchable Ceramides Enable Optical Control of Apoptosis.
In: ACS Chemical Biology, Bd. 16, Nr. 3: S. 452-456
Pritzl, Stefanie D.; Konrad, David B.; Ober, Martina F.; Richter, Alexander F.; Frank, James A.; Nickel, Bert; Trauner, Dirk und Lohmüller, Theobald
(2021):
Optical Membrane Control with Red Light Enabled by Red-Shifted Photolipids.
In: Langmuir, Bd. 38, Nr. 1: S. 385-393
Reynders, Martin; Chaikuad, Apirat; Berger, Benedict-Tilman; Bauer, Katharina; Koch, Pierre; Laufer, Stefan; Knapp, Stefan und Trauner, Dirk
(2021):
Controlling the Covalent Reactivity of a Kinase Inhibitor with Light.
In: Angewandte Chemie-International Edition, Bd. 60, Nr. 37: S. 20178-20183
Müller-Deku, Adrian; Meiring, Joyce C. M.; Loy, Kristina; Kraus, Yvonne; Heise, Constanze; Bingham, Rebekkah; Jansen, Klara I.; Qu, Xiaoyi; Bartolini, Francesca; Kapitein, Lukas C.; Akhmanova, Anna; Ahlfeld, Julia; Trauner, Dirk und Thorn-Seshold, Oliver
(2020):
Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton.
In: Nature communications, Bd. 11, Nr. 1, 4640
[PDF, 7MB]
Kopf, Aglaja; Renkawitz, Jörg; Hauschild, Robert; Girkontaite, Irute; Tedford, Kerry; Merrin, Jack; Thorn-Seshold, Oliver; Trauner, Dirk; Haecker, Hans; Fischer, Klaus-Dieter; Kiermaier, Eva und Sixt, Michael
(2020):
Microtubules control cellular shape and coherence in amoeboid migrating cells.
In: Journal of Cell Biology, Bd. 219, Nr. 6, e201907154
Urban, Patrick; Pritzl, Stefanie D.; Ober, Martina F.; Dirscherl, Christina F.; Pernpeintner, Carla; Konrad, David B.; Frank, James A.; Trauner, Dirk; Nickel, Bert und Lohmueller, Theobald
(2020):
A Lipid Photoswitch Controls Fluidity in Supported Bilayer Membranes.
In: Langmuir, Bd. 36, Nr. 10: S. 2629-2634
Borowiak, Malgorzata; Kuellmer, Florian; Gegenfurtner, Florian; Peil, Sebastian; Nasufovic, Veselin; Zahler, Stefan; Thorn-Seshold, Oliver; Trauner, Dirk und Arndt, Hans-Dieter
(2020):
Optical Manipulation of F-Actin with Photoswitchable Small Molecules.
In: Journal of the American Chemical Society, Bd. 142, Nr. 20: S. 9240-9249
Scheidt, Holger A.; Kolocaj, Katja; Konrad, David B.; Frank, James A.; Trauner, Dirk; Langosch, Dieter und Huster, Daniel
(2020):
Light-induced lipid mixing implies a causal role of lipid splay in membrane fusion.
In: Biochimica et Biophysica Acta-Biomembranes, Bd. 1862, Nr. 11, 183438
Hinnah, Konstantin; Willems, Sabine; Morstein, Johannes; Heering, Jan; Hartrampf, Felix W. W.; Broichhagen, Johannes; Leippe, Philipp; Merk, Daniel und Trauner, Dirk
(2020):
Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor gamma (PPAR gamma).
In: Journal of Medicinal Chemistry, Bd. 63, Nr. 19: S. 10908-10920
Quintela-Varela, Hugo; Jamieson, Cooper S.; Shao, Qianzhen; Houk, K. N. und Trauner, Dirk
(2020):
Bioinspired Synthesis of (-)-PF-1018.
In: Angewandte Chemie-International Edition, Bd. 59, Nr. 13: S. 5263-5267
Leippe, Philipp; Broichhagen, Johannes; Cailliau, Katia; Mougel, Alexandra; Morel, Marion; Dissous, Colette; Trauner, Dirk und Vicogne, Jerome
(2020):
Transformation of Receptor Tyrosine Kinases into Glutamate Receptors and Photoreceptors.
In: Angewandte Chemie-International Edition, Bd. 59, Nr. 17: S. 6720-6723
Hartrampf, Nina; Seki, Toshiyuki; Baumann, Andreas; Watson, Philip; Veprek, Nynke A.; Hetzler, Belinda E.; Hoffmann-Roder, Anja; Tsuji, Moriya und Trauner, Dirk
(2020):
Optical Control of Cytokine Production Using Photoswitchable Galactosylceramides.
In: Chemistry-A European Journal, Bd. 26, Nr. 20: S. 4476-4479
Reynders, Martin; Matsuura, Bryan S.; Berouti, Marleen; Simoneschi, Daniele; Marzio, Antonio; Pagano, Michele und Trauner, Dirk
(2020):
PHOTACs enable optical control of protein degradation.
In: Science Advances, Bd. 6, Nr. 8, eaay5064
Morstein, Johannes; Trads, Julie B.; Hinnah, Konstantin; Willems, Sabine; Barber, David M.; Trauner, Michael; Merk, Daniel und Trauner, Dirk
(2020):
Optical control of the nuclear bile acid receptor FXR with a photohormone.
In: Chemical Science, Bd. 11, Nr. 2: S. 429-434
Maier, Martin S.; Huell, Katharina; Reynders, Martin; Matsuura, Bryan S.; Leippe, Philipp; Ko, Tongil; Schaeffer, Lukas und Trauner, Dirk
(2019):
Oxidative Approach Enables Efficient Access to Cyclic Azobenzenes.
In: Journal of the American Chemical Society, Bd. 141, Nr. 43: S. 17295-17304
Trads, Julie B.; Huell, Katharina; Matsuura, Bryan S.; Laprell, Laura; Fehrentz, Timm; Gorldt, Nicole; Kozek, Krystian A.; Weaver, C. David; Klocker, Nikolaj; Barber, David M. und Trauner, Dirk
(2019):
Sign Inversion in Photopharmacology: Incorporation of Cyclic Azobenzenes in Photoswitchable Potassium Channel Blockers and Openers.
In: Angewandte Chemie-International Edition, Bd. 58, Nr. 43: S. 15421-15428
Morstein, Johannes; Hill, Rose Z.; Novak, Alexander J. E.; Feng, Suihan; Norman, Derek D.; Donthamsetti, Prashant C.; Frank, James A.; Harayama, Takeshi; Williams, Benjamin M.; Parrill, Abby L.; Tigyi, Gabor J.; Riezman, Howard; Isacoff, Ehud Y.; Bautista, Diana M. und Trauner, Dirk
(2019):
Optical control of sphingosine-1-phosphate formation and function.
In: Nature Chemical Biology, Bd. 15, Nr. 6
Kol, Matthijs; Williams, Ben; Toombs-Ruane, Henry; Franquelim, Henri G.; Korneev, Sergei; Schroeer, Christian; Schwille, Petra; Trauner, Dirk; Holthuis, Joost C. M. und Frank, James A.
(2019):
Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides.
In: eLife, Bd. 8, e43230
[PDF, 5MB]
Haefner, Stephanie; Burg, Finn; Kannler, Martina; Urban, Nicole; Mayer, Peter; Dietrich, Alexander; Trauner, Dirk; Broichhagen, Johannes und Schaefer, Michael
(2018):
A (+)-Larixol Congener with High Affinity and Subtype Selectivity toward TRPC6.
In: Chemmedchem, Bd. 13, Nr. 10: S. 1028-1035
Leinders-Zufall, Trese; Storch, Ursula; Bleymehl, Katherin; Mederos y Schnitzler, Michael; Frank, James A.; Konrad, David B.; Trauner, Dirk; Gudermann, Thomas und Zufall, Frank
(2018):
PhoDAGs Enable Optical Control of Diacylglycerol-Sensitive Transient Receptor Potential Channels.
In: Cell Chemical Biology, Bd. 25, Nr. 2: S. 215-223
Urban, Patrick; Pritzl, Stefanie D.; Konrad, David B.; Frank, James A.; Pernpeintner, Carla; Roeske, Christian R.; Trauner, Dirk und Lohmüller, Theobald
(2018):
Light-Controlled Lipid Interaction and Membrane Organization in Photolipid Bilayer Vesicles.
In: Langmuir, Bd. 34, Nr. 44: S. 13368-13374
Podewin, Tom; Ast, Julia; Broichhagen, Johannes; Fine, Nicholas H. F.; Nasteska, Daniela; Leippe, Philipp; Gailer, Manuel; Buenaventura, Teresa; Kanda, Nisha; Jones, Ben J.; M'Kadmi, Celine; Baneres, Jean-Louis; Marie, Jacky; Tomas, Alejandra; Trauner, Dirk; Hoffmann-Röder, Anja und Hodson, David J.
(2018):
Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology.
In: ACS Central Science, Bd. 4, Nr. 2: S. 166-179
[PDF, 6MB]
Fehrentz, Timm; Huber, Florian M. E.; Hartrampf, Nina; Bruegmann, Tobias; Frank, James A.; Fine, Nicholas H. F.; Malan, Daniela; Danzl, Johann G.; Tikhonov, Denis B.; Sumser, Martin; Sasse, Philipp; Hodson, David J.; Zhorov, Boris S.; Klocker, Nikolaj und Trauner, Dirk
(2018):
Optical control of L-type Ca2+ channels using a diltiazem photoswitch.
In: Nature Chemical Biology, Bd. 14, Nr. 8: S. 764-767
Barber, David M.; Liu, Shu-An; Gottschling, Kevin; Sumser, Martin; Hollmann, Michael und Trauner, Dirk
(2017):
Optical control of AMPA receptors using
a photoswitchable quinoxaline-2,3-dione
antagonist.
In: Chemical Science, Bd. 8, Nr. 1: S. 611-615
[PDF, 564kB]
Berry, Michael H.; Holt, Amy; Levitz, Joshua; Broichhagen, Johannes; Gaub, Benjamin M.; Visel, Meike; Stanley, Cherise; Aghi, Krishan; Kim, Yang Joon; Trauner, Dirk; Flannery, John und Isacoff, Ehud Y.
(2017):
Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor.
In: Nature Communications, Bd. 8, 1862
[PDF, 2MB]
Frank, James Allen; Yushchenko, Dmytro A.; Fine, Nicholas H. F.; Duca, Margherita; Citir, Mevlut; Broichhagen, Johannes; Hodson, David J.; Schultz, Carsten und Trauner, Dirk
(2017):
Optical control of GPR40 signalling in pancreatic beta-cells.
In: Chemical Science, Bd. 8, Nr. 11: S. 7604-7610
Bihelovic, Filip; Stichnoth, Desiree; Surup, Frank; Müller, Rolf und Trauner, Dirk
(2017):
Total Synthesis of CrocaginA.
In: Angewandte Chemie-international Edition, Bd. 56, Nr. 42: S. 12848-12851
Viehrig, Konrad; Surup, Frank; Volz, Carsten; Herrmann, Jennifer; Abou Fayad, Antoine; Adam, Sebastian; Köhnke, Jesko; Trauner, Dirk und Müller, Rolf
(2017):
Structure and Biosynthesis of Crocagins: Polycyclic Posttranslationally Modified Ribosomal Peptides from Chondromyces crocatus.
In: Angewandte Chemie-international Edition, Bd. 56, Nr. 26: S. 7407-7410
Podewin, Tom; Broichhagen, Johannes; Frost, Christina; Groneberg, Dieter; Ast, Julia; Meyer-Berg, Helena; Fine, Nicholas H. F.; Friebe, Andreas; Zacharias, Martin; Hodson, David J.; Trauner, Dirk und Hoffmann-Röder, Anja
(2017):
Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone.
In: Chemical Science, Bd. 8, Nr. 6: S. 4644-4653
Mehta, Zenobia B.; Johnston, Natalie R.; Nguyen-Tu, Marie-Sophie; Broichhagen, Johannes; Schultz, Peter; Larner, Dean P.; Leclerc, Isabelle; Trauner, Dirk; Rutter, Guy A. und Hodson, David J.
(2017):
Remote control of glucose homeostasis in vivo using photopharmacology.
In: Scientific Reports, Bd. 7, 291
[PDF, 4MB]
Laprell, Laura; Tochitsky, Ivan; Kaur, Kuldeep; Manookin, Michael B.; Stein, Marco; Barber, David M.; Schön, Christian; Michalakis, Stylianos; Biel, Martin; Kramer, Richard H.; Sumser, Martin P.; Trauner, Dirk und Gelder, Russell N. van
(2017):
Photopharmacological control of bipolar cells restores visual function in blind mice.
In: Journal of Clinical investigation, Bd. 127, Nr. 7: S. 2598-2611
Trads, Julie B.; Burgstaller, Jessica; Laprell, Laura; Konrad, David B.; Osa de la Rosa, Luis de la; Weaver, C. David; Baier, Herwig; Trauner, Dirk und Barber, David M.
(2017):
Optical control of GIRK channels using visible light.
In: Organic & Biomolecular Chemistry, Bd. 15, Nr. 1: S. 76-81
Schell, Ursula; Simon, Sylvia; Sahr, Tobias; Hager, Dominik; Albers, Michael F.; Kessler, Aline; Fahrnbauer, Felix; Trauner, Dirk; Hedberg, Christian; Buchrieser, Carmen und Hilbi, Hubert
(2016):
The α-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signalling and gene expression of Legionella pneumophila.
In: Molecular Microbiology, Bd. 99, Nr. 4: S. 778-793
Johnston, Natalie R.; Mitchell, Ryan K.; Haythorne, Elizabeth; Pessoa, Maria Paiva; Semplici, Francesca; Ferrer, Jorge; Piemonti, Lorenzo; Marchetti, Piero; Bugliani, Marco; Bosco, Domenico; Berishvili, Ekaterine; Duncanson, Philip; Watkinson, Michael; Broichhagen, Johannes; Trauner, Dirk; Rutter, Guy A. und Hodson, David J.
(2016):
Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose.
In: Cell Metabolism, Bd. 24, Nr. 3: S. 389-401
Frank, James Allen; Yushchenko, Dmytro A.; Hodson, David J.; Lipstein, Noa; Nagpal, Jatin; Rutter, Guy A.; Rhee, Jeong-Seop; Gottschalk, Alexander; Brose, Nils; Schultz, Carsten und Trauner, Dirk
(2016):
Photoswitchable diacylglycerols enable optical control of protein kinase C.
In: Nature Chemical Biology, Bd. 12, Nr. 9: S. 755-762
Broichhagen, Johannes; Johnston, Natalie R.; Ohlen, Yorrick von; Meyer-Berg, Helena; Jones, Ben J.; Bloom, Stephen R.; Rutter, Guy A.; Trauner, Dirk und Hodson, David J.
(2016):
Allosteric Optical Control of a Class B G-Protein-Coupled Receptor.
In: Angewandte Chemie-international Edition, Bd. 55, Nr. 19: S. 5865-5868
Barber, David M.; Schönberger, Matthias; Burgstaller, Jessica; Levitz, Joshua; Weaver, C. David; Isacoff, Ehud Y.; Baier, Herwig und Trauner, Dirk
(2016):
Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO).
In: Chemical Science, Bd. 7, Nr. 3: S. 2347-2352
Simon, Sylvia; Schell, Ursula; Heuer, Natalie; Hager, Dominik; Albers, Michael F.; Matthias, Jan; Fahrnbauer, Felix; Trauner, Dirk; Eichinger, Ludwig; Hedberg, Christian und Hilbi, Hubert
(2015):
Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway.
In: PLOS Pathogens
11(12), e1005307
[PDF, 6MB]
Broichhagen, Johannes; Damijonaitis, Arunas; Levitz, Joshua; Sokol, Kevin R.; Leippe, Philipp; Konrad, David; Isacoff, Ehud Y. und Trauner, Dirk
(2015):
Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand.
In: ACS Central Science, Bd. 1, Nr. 7: S. 383-393
Laprell, Laura; Repak, Emilienne; Franckevicius, Vilius; Hartrampf, Felix; Terhag, Jan; Hollmann, Michael; Sumser, Martin; Rebola, Nelson; DiGregorio, David A. und Trauner, Dirk
(2015):
Optical control of NMDA receptors with a diffusible photoswitch.
In: Nature Communications, Bd. 6, 8076
[PDF, 2MB]
Broichhagen, Johannes; Frank, J. A.; Johnston, N. R.; Mitchell, R. K.; Šmid, K.; Marchetti, P.; Bugliani, M.; Rutter, Guy A.; Trauner, Dirk und Hodson, David J.
(2015):
A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function.
In: Chemical Communications, Bd. 51, Nr. 27: S. 6018-6021
[PDF, 5MB]
Broichhagen, Johannes; Schönberger, Matthias; Cork, Simon C.; Frank, James A.; Marchetti, Piero; Bugliani, Marco; Shapiro, A. M. James; Trapp, Stefan; Rutter, Guy A.; Hodson, David J. und Trauner, Dirk
(2014):
Optical control of insulin release using a photoswitchable sulfonylurea.
In: Nature Communications, Bd. 5, 5116
[PDF, 3MB]
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