Anzahl der Publikationen auf dieser Ebene: 255
Zeitschriftenartikel
Abraham, G.; Malik, Rainer; Yonova-Doing, E.; Salim, Agus; Wang, T.; Danesh, John; Butterworth, Adam S.; Howson, Joanna M. M.; Inouye, M. und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(20. Dezember 2019):
Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke.
In: Nature Communications, 5819
[PDF, 1MB]
Abudu, Yakubu Princely; Shrestha, Birendra Kumar; Zhang, Wenxin; Palara, Anthimi; Brenne, Hanne Britt; Larsen, Kenneth Bowitz; Wolfson, Deanna Lynn; Dumitriu, Gianina; Oie, Cristina Ionica; Ahluwalia, Balpreet Singh; Levy, Gahl; Behrends, Christian; Tooze, Sharon A.; Mouilleron, Stephane; Lamark, Trond und Johansen, Terje
(2021):
SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components.
In: Journal of Cell Biology, Bd. 220, Nr. 8, e202009092
[PDF, 10MB]
Araque Caballero, Miguel Á.; Song, Zhuang; Rubinski, Anna; Düring, Marco; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Park, Denise C. und Ewers, Michael
(April 2020):
Age‐dependent amyloid deposition is associated with white matter alterations in cognitively normal adults during the adult life span.
In: Alzheimer's & Dementia, Bd. 16, Nr. 4: S. 651-661
[PDF, 1MB]
Arlt, Friederike A. ORCID: https://orcid.org/0000-0002-0112-8685; Sperber, Pia S. ORCID: https://orcid.org/0000-0002-9534-2374; Rennenberg, Regina von; Gebert, Pimrapat; Teegen, Bianca; Georgakis, Marios ORCID: https://orcid.org/0000-0003-3507-3659; Fang, Rong ORCID: https://orcid.org/0000-0002-5663-9407; Dewenter, Anna ORCID: https://orcid.org/0000-0002-5636-196X; Görtler, Michael; Petzold, Gabor C.; Wunderlich, Silke; Zerr, Inga ORCID: https://orcid.org/0000-0002-6722-2463; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Prüss, Harald ORCID: https://orcid.org/0000-0002-8283-7976; Endres, Matthias ORCID: https://orcid.org/0000-0001-6520-3720; Liman, Thomas; Nolte, Christian; Kerti, Lucia; Wittenberg, Tatjana; Scheitz, Jan F.; Nave, Alexander H.; Kufner, Anna Ibaroule; Bode, Felix; Stösser, Sebastian; Meißner, Julius N.; Ebrahimi, Taraneh; Nordsiek, Julia; Beckonert, Niklas; Hermann, Peter; Schmitz, Matthias; Goebel, Stefan; Schütte-Schmidt, Julia; Nuhn, Sabine; Volpers, Corinna; Dechent, Peter; Bähr, Matthias; Glanz, Wenzel ORCID: https://orcid.org/0000-0002-5865-4176; Tiedt, Steffen ORCID: https://orcid.org/0000-0002-8817-8457; Waegemann, Karin; Janowitz, Daniel ORCID: https://orcid.org/0009-0003-4090-547X; Ikenberg, Benno; Bermkopf, Kathleen; Huber, Christiane; Wagner, Michael ORCID: https://orcid.org/0000-0003-2589-6440; Neumann, Katja; Spottke, Annika ORCID: https://orcid.org/0000-0001-9854-2972; Stöcker, Tony; Dühring, Marco; Speck, Oliver; Duezel, Emrah und Bartenstein, Peter
(2024):
Serum anti-NMDA receptor antibodies are linked to memory impairment 12 months after stroke.
In: Molecular Psychiatry [Forthcoming]
Asare, Yaw ORCID: https://orcid.org/0000-0002-8946-5650; Shnipova, Margarita; Živković, Luka; Schlegl, Christina ORCID: https://orcid.org/0000-0001-7314-5954; Tosato, Federica ORCID: https://orcid.org/0000-0002-2783-4764; Aronova, Arailym ORCID: https://orcid.org/0000-0002-1337-2415; Brandhofer, Markus; Strohm, Laura; Beaufort, Nathalie; Malik, Rainer; Weber, Christian ORCID: https://orcid.org/0000-0003-4610-8714; Bernhagen, Jürgen ORCID: https://orcid.org/0000-0003-2996-2652 und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2022):
IKKβ binds NLRP3 providing a shortcut to inflammasome activation for rapid immune responses.
In: Signal Transduction and Targeted Therapy, Bd. 7, 355
[PDF, 1MB]
Asare, Y.; Campbell-James, T. A.; Bokov, Y.; Yu, L. L.; Prestel, M.; El Bounkari, O.; Roth, S.; Megens, Remco; Straub, T.; Thomas, K.; Yan, G.; Schneider, M.; Ziesch, N.; Tiedt, Steffen; Silvestre-Roig, Carlos; Braster, Quinte; Huang, Y.; Schneider, M.; Malik, Rainer; Haffner, Christof; Liesz, Arthur; Soehnlein, Oliver; Bernhagen, Jürgen und Dichgans, Martin
(17. Juni 2020):
Histone Deacetylase 9 Activates IKK to Regulate Atherosclerotic Plaque Vulnerability.
In: Circulation Research
[PDF, 18MB]
Auffenberg, Eva; Hedrich, Ulrike B. S.; Barbieri, Raffaella; Miely, Daniela; Groschup, Bernhard; Wuttke, Thomas V.; Vogel, Niklas; Luehrs, Philipp; Zanardi, Ilaria; Bertelli, Sara; Spielmann, Nadine; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Pusch, Michael; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Lerche, Holger; Gavazzo, Paola; Plesnila, Nikolaus und Freilinger, Tobias
(2021):
Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model.
In: Journal of Clinical Investigation, Bd. 131, Nr. 21, e142202
[PDF, 3MB]
Baker, Emily; Sims, Rebecca; Leonenko, Ganna; Frizzati, Aura; Harwood, Janet C.; Grozeva, Detelina; Morgan, Kevin; Passmore, Peter; Holmes, Clive; Powell, John; Brayne, Carol; Gill, Michael; Mead, Simon; Bossu, Paola; Spalletta, Gianfranco; Cruchaga, Carlos; Maier, Wolfgang; Heun, Reinhard; Jessen, Frank; Peters, Oliver; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Frölich, Lutz; Ramirez, Alfredo; Jones, Lesley; Hardy, John; Ivanov, Dobril; Hill, Matthew; Holmans, Peter; Allen, Nicholas D.; Morgan, B. Paul; Seshadri, Sudha; Schellenberg, Gerard D.; Amouyel, Philippe; Williams, Julie und Escott-Price, Valentina
(2019):
Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.
In: PLOS One
14(7), e0218111
[PDF, 905kB]
Bakker, Mark K.; Spek, Rick A. A. van der; Rheenen, Wouter van; Morel, Sandrine; Bourcier, Romain; Hostettler, Isabel C.; Alg, Varinder S.; Eijk, Kristel R. van; Koido, Masaru; Akiyama, Masato; Terao, Chikashi; Matsuda, Koichi; Walters, Robin G.; Lin, Kuang; Li, Liming; Millwood, Iona Y.; Chen, Zhengming; Rouleau, Guy A.; Zhou, Sirui; Rannikmae, Kristiina; Sudlow, Cathie L. M.; Houlden, Henry; Berg, Leonard H. van den; Dina, Christian; Naggara, Olivier; Gentric, Jean-Christophe; Shotar, Eimad; Eugene, Francois; Desal, Hubert; Winsvold, Bendik S.; Borte, Sigrid; Johnsen, Marianne Bakke; Brumpton, Ben M.; Sandvei, Marie Softeland; Willer, Cristen J.; Hveem, Kristian; Zwart, John-Anker; Verschuren, W. M. Monique; Friedrich, Christoph M.; Hirsch, Sven; Schilling, Sabine; Dauvillier, Jerome; Martin, Olivier; Winsvold, Bendik S.; Winsvold, Bendik S.; Borte, Sigrid; Johnsen, Marianne Bakke; Brumpton, Ben M.; Sandvei, Marie Softeland; Willer, Cristen J.; Hveem, Kristian; Zwart, John-Anker; Bian, Zheng; Chen, Junshi; Chen, Yiping; Chen, Zhengming; Clarke, Robert; Collins, Rory; Guo, Yu; Han, Xiao; Hill, Michael; Li, Liming; Lin, Kuang; Liu, Depei; Lv, Jun; Millwood, Iona; Peto, Richard; Sansome, Sam; Walters, Robin; Yang, Xiaoming; Yu, Canqing; Koido, Masaru; Koido, Masaru; Akiyama, Masato; Terao, Chikashi; Matsuda, Koichi; Kamatani, Yoichiro; Desal, Hubert; Desal, Hubert; Bourcier, Romain; Redon, Richard; Dina, Christian; Naggara, Olivier; Eugene, Francois; Gentric, Jean-Christophe; Shotar, Eimad; Sargurupremraj, Muralidharan; Tatlisumak, Turgut; Debette, Stephanie; Werring, David J.; Houlden, Henry; Alg, Varinder S.; Hostettler, Isabel C.; Bonner, Stephen; Walsh, Daniel; Bulters, Diederik; Kitchen, Neil; Brown, Martin; Grieve, Joan; Bakker, Mark K.; Bourcier, Romain; Walters, Robin G.; Malik, Rainer; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Sargurupremraj, Muralidharan; Tatlisumak, Turgut; Debette, Stephanie; Rinkel, Gabriel J. E.; Worrall, Bradford B.; Pera, Joanna; Slowik, Agnieszka; Broderick, Joseph P.; Werring, David J.; Woo, Daniel; Bijlenga, Philippe; Kamatani, Yoichiro; Ruigrok, Ynte M.; Jones, Gregory T.; Bown, Matthew J.; Ko, Nerissa U.; Kim, Helen; Coleman, Jonathan R. I.; Breen, Gerome; Zaroff, Jonathan G.; Klijn, Catharina J. M.; Malik, Rainer; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Sargurupremraj, Muralidharan; Tatlisumak, Turgut; Amouyel, Philippe; Debette, Stephanie; Rinkel, Gabriel J. E.; Worrall, Bradford B.; Pera, Joanna; Slowik, Agnieszka; Gaal-Paavola, Emilia I.; Niemela, Mika; Jaaskelainen, Juha E.; Fraunberg, Mikael von und zu; Lindgren, Antti; Broderick, Joseph P.; Werring, David J.; Woo, Daniel; Redon, Richard; Bijlenga, Philippe; Kamatani, Yoichiro; Veldink, Jan H. und Ruigrok, Ynte M.
(2020):
Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors.
In: Nature Genetics, Bd. 52, Nr. 12: S. 1303-1313
[PDF, 1MB]
Bartos, Laura M. ORCID: https://orcid.org/0009-0007-6158-319X; Kunte, Sebastian T. ORCID: https://orcid.org/0009-0007-3543-5329; Wagner, Stephan; Beumers, Philipp; Schaefer, Rebecca ORCID: https://orcid.org/0009-0006-7218-0591; Zatcepin, Artem ORCID: https://orcid.org/0000-0002-0224-088X; Li, Yunlei ORCID: https://orcid.org/0009-0006-7156-5959; Griessi, Maria; Hoermann, Leonie; Wind-Mark, Karin; Bartenstein, Peter ORCID: https://orcid.org/0009-0005-0734-4994; Tahirovic, Sabina ORCID: https://orcid.org/0000-0003-4403-9559; Ziegler, Sibylle I. ORCID: https://orcid.org/0000-0002-5321-4817; Brendel, Matthias ORCID: https://orcid.org/0000-0002-9247-2843 und Gnörich, Johannes ORCID: https://orcid.org/0000-0003-1554-7765
(2024):
Astroglial glucose uptake determines brain FDG-PET alterations and metabolic connectivity during healthy aging in mice.
In: NeuroImage, Bd. 300, 120860
[PDF, 5MB]
Beaufort, N.; Scharrer, E.; Kremmer, E.; Lux, V.; Ehrmann, M.; Huber, R.; Houlden, H.; Werring, D.; Haffner, C. und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2016):
Cerebral small vessel disease-related protease HtrA1 processes latent TGF-beta binding protein 1 and facilitates TGF-beta signalling.
In: Journal of Cerebral Blood Flow and Metabolism, Bd. 36: S. 746
Beaufort, Nathalie ORCID: https://orcid.org/0000-0002-7088-4206; Ingendahl, Linda; Merdanovic, Melisa; Schmidt, Andree ORCID: https://orcid.org/0000-0002-8254-0777; Podlesainski, David ORCID: https://orcid.org/0000-0002-1111-8042; Richter, Tim ORCID: https://orcid.org/0009-0003-8310-6803; Neumann, Thorben; Kuszner, Michael; Vetter, Ingrid R.; Stege, Patricia; Burston, Steven G. ORCID: https://orcid.org/0000-0003-1848-1853; Filipovic, Anto; Ruiz-Blanco, Yasser B.; Bravo-Rodriguez, Kenny; Mieres-Perez, Joel ORCID: https://orcid.org/0000-0002-7875-0886; Beuck, Christine ORCID: https://orcid.org/0000-0001-7513-7384; Uebel, Stephan ORCID: https://orcid.org/0000-0002-3726-3942; Zobawa, Monika; Schillinger, Jasmin; Malik, Rainer ORCID: https://orcid.org/0000-0001-9212-2520; Todorov-Völgyi, Katalin ORCID: https://orcid.org/0009-0007-8073-9524; Rey, Juliana; Roberti, Annabell; Hagemeier, Birte; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Müller, Stephan A. ORCID: https://orcid.org/0000-0003-3414-307X; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Sanchez-Garcia, Elsa; Zimmermann, Alexander; Hu, Xiao-Yu ORCID: https://orcid.org/0000-0002-9634-315X; Clausen, Tim ORCID: https://orcid.org/0000-0003-1582-6924; Huber, Robert; Lichtenthaler, Stefan F. ORCID: https://orcid.org/0000-0003-2211-2575; Schmuck, Carsten ORCID: https://orcid.org/0000-0001-6062-0357; Giese, Michael; Kaiser, Markus ORCID: https://orcid.org/0000-0002-6540-8520; Ehrmann, Michael ORCID: https://orcid.org/0000-0002-1927-260X und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2024):
Rational correction of pathogenic conformational defects in HTRA1.
In: Nature Communications, Bd. 15, 5944
[PDF, 3MB]
Bernal, Jose; Menze, Inga; Yakupov, Renat; Peters, Oliver; Hellmann-Regen, Julian; Freiesleben, Silka Dawn; Priller, Josef; Spruth, Eike Jakob; Altenstein, Slawek; Schneider, Anja; Fliessbach, Klaus; Wiltfang, Jens; Schott, Björn H.; Jessen, Frank; Rostamzadeh, Ayda; Glanz, Wenzel; Incesoy, Enise I.; Buerger, Katharina ORCID: https://orcid.org/0000-0002-5898-9953; Janowitz, Daniel ORCID: https://orcid.org/0009-0003-4090-547X; Ewers, Michael ORCID: https://orcid.org/0000-0001-5231-1714; Perneczky, Robert ORCID: https://orcid.org/0000-0003-1981-7435; Rauchmann, Boris-Stephan ORCID: https://orcid.org/0000-0003-4547-6240; Teipel, Stefan; Kilimann, Ingo; Laske, Christoph; Sodenkamp, Sebastian; Spottke, Annika; Esser, Anna; Lüsebrink, Falk; Dechent, Peter; Hetzer, Stefan; Scheffler, Klaus; Schreiber, Stefanie; Düzel, Emrah und Ziegler, Gabriel
(2024):
Longitudinal evidence for a mutually reinforcing relationship between white matter hyperintensities and cortical thickness in cognitively unimpaired older adults.
In: Alzheimer's Research & Therapy
16:240
[PDF, 3MB]
Biel, Davina; Brendel, Matthias; Rubinski, Anna; Buerger, Katharina; Janowitz, Daniel; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X und Franzmeier, Nicolai
(2021):
Tau-PET and in vivo Braak-staging as prognostic markers of future cognitive decline in cognitively normal to demented individuals.
In: Alzheimer's research & therapy, Bd. 13, 137
[PDF, 2MB]
Biel, Davina ORCID: https://orcid.org/0000-0002-2597-1992; Suárez‐Calvet, Marc ORCID: https://orcid.org/0000-0002-2993-569X; Hager, Paul; Rubinski, Anna; Dewenter, Anna; Steward, Anna; Roemer, Sebastian; Ewers, Michael; Haass, Christian; Brendel, Matthias ORCID: https://orcid.org/0000-0002-9247-2843 und Franzmeier, Nicolai ORCID: https://orcid.org/0000-0001-9736-2283
(2023):
sTREM2 is associated with amyloid‐related p‐tau increases and glucose hypermetabolism in Alzheimer's disease.
In: EMBO Molecular Medicine, Bd. 15, Nr. 2
[PDF, 1MB]
Blömeke, Lara ORCID: https://orcid.org/0000-0002-8861-9224; Rehn, Fabian ORCID: https://orcid.org/0000-0001-8815-0684; Pils, Marlene ORCID: https://orcid.org/0000-0002-1506-3675; Kraemer-Schulien, Victoria ORCID: https://orcid.org/0000-0002-7413-7646; Cousin, Anneliese; Kutzsche, Janine ORCID: https://orcid.org/0000-0003-0271-7390; Bujnicki, Tuyen ORCID: https://orcid.org/0000-0002-7191-8455; Freiesleben, Silka D. ORCID: https://orcid.org/0000-0002-2141-8671; Schneider, Luisa-Sophie ORCID: https://orcid.org/0000-0001-5822-1744; Preis, Lukas; Priller, Josef; Spruth, Eike J.; Altenstein, Slawek; Schneider, Anja ORCID: https://orcid.org/0000-0001-9540-8700; Fliessbach, Klaus; Wiltfang, Jens ORCID: https://orcid.org/0000-0003-1492-5330; Hansen, Niels ORCID: https://orcid.org/0000-0001-5785-9594; Rostamzadeh, Ayda; Düzel, Emrah; Glanz, Wenzel; Incesoy, Enise I. ORCID: https://orcid.org/0000-0003-2014-4098; Buerger, Katharina ORCID: https://orcid.org/0000-0002-5898-9953; Janowitz, Daniel ORCID: https://orcid.org/0009-0003-4090-547X; Ewers, Michael; Perneczky, Robert ORCID: https://orcid.org/0000-0003-1981-7435; Rauchmann, Boris-Stephan ORCID: https://orcid.org/0000-0003-4547-6240; Teipel, Stefan; Kilimann, Ingo; Laske, Christoph; Munk, Matthias H.; Spottke, Annika; Roy, Nina; Heneka, Michael T. ORCID: https://orcid.org/0000-0003-4996-1630; Brosseron, Frederic ORCID: https://orcid.org/0000-0003-3137-7516; Wagner, Michael ORCID: https://orcid.org/0000-0003-2589-6440; Roeske, Sandra; Ramirez, Alfredo ORCID: https://orcid.org/0000-0003-4991-763X; Schmid, Matthias; Jessen, Frank; Bannach, Oliver; Peters, Oliver und Willbold, Dieter ORCID: https://orcid.org/0000-0002-0065-7366
(2024):
Blood-based quantification of Aβ oligomers indicates impaired clearance from brain in ApoE ε4 positive subjects.
In: Communications Medicine, Bd. 4, 262
[PDF, 2MB]
Bonelli, Simone ORCID: https://orcid.org/0009-0003-7789-2502; Pinto, Margot Lo ORCID: https://orcid.org/0009-0003-0394-9414; Ye, Yihong; Müller, Stephan A. ORCID: https://orcid.org/0000-0003-3414-307X; Lichtenthaler, Stefan F. ORCID: https://orcid.org/0000-0003-2211-2575 und Scilabra, Simone Dario ORCID: https://orcid.org/0000-0001-7300-6153
(2024):
Proteomic Characterization of Ubiquitin Carboxyl-Terminal Hydrolase 19 Deficient Cells Reveals a Role for USP19 in the Secretion of Lysosomal Proteins.
In: Molecular & Cellular Proteomics, Bd. 23, Nr. 11, 100854
[PDF, 3MB]
Boni, Laura de ORCID: https://orcid.org/0000-0001-7785-482X; Wallis, Amber; Hays Watson, Aurelia; Ruiz-Riquelme, Alejandro ORCID: https://orcid.org/0000-0001-6581-7132; Leyland, Louise-Ann; Bourinaris, Thomas; Hannaway, Naomi; Wüllner, Ullrich; Peters, Oliver; Priller, Josef ORCID: https://orcid.org/0000-0001-7596-0979; Falkenburger, Björn H; Wiltfang, Jens ORCID: https://orcid.org/0000-0003-1492-5330; Bähr, Mathias; Zerr, Inga; Bürger, Katharina; Perneczky, Robert ORCID: https://orcid.org/0000-0003-1981-7435; Teipel, Stefan; Löhle, Matthias; Hermann, Wiebke; Schott, Björn-Hendrik ORCID: https://orcid.org/0000-0002-8237-4481; Brockmann, Kathrin; Spottke, Annika; Haustein, Katrin; Breuer, Peter; Houlden, Henry; Weil, Rimona S ORCID: https://orcid.org/0000-0002-5092-6325 und Bartels, Tim ORCID: https://orcid.org/0000-0002-4071-5612
(2024):
Aggregation-resistant alpha-synuclein tetramers are reduced in the blood of Parkinson’s patients.
In: EMBO Molecular Medicine, Bd. 16, Nr. 7: S. 1657-1674
[PDF, 3MB]
Borrego-Ecija, Sergi ORCID: https://orcid.org/0000-0003-2557-0010; Juncà-Parella, Jordi; Vandebergh, Marijne ORCID: https://orcid.org/0000-0001-9645-2615; Pérez Millan, Agnès; Balasa, Mircea; Llado, Albert; Bouzigues, Arabella ORCID: https://orcid.org/0000-0002-0267-8590; Russell, Lucy Louise ORCID: https://orcid.org/0000-0001-5023-5893; Foster, Phoebe H. ORCID: https://orcid.org/0000-0001-6300-6598; Ferry-Bolder, Eve ORCID: https://orcid.org/0009-0006-5083-0901; Swieten, John C. Van ORCID: https://orcid.org/0000-0001-6278-6844; Jiskoot, Lize Corrine ORCID: https://orcid.org/0000-0002-1120-1858; Seelaar, Harro ORCID: https://orcid.org/0000-0003-1989-7527; Laforce, Robert ORCID: https://orcid.org/0000-0002-2031-490X; Graff, Caroline ORCID: https://orcid.org/0000-0002-9949-2951; Galimberti, Daniela ORCID: https://orcid.org/0000-0002-9284-5953; Vandenberghe, Rik ORCID: https://orcid.org/0000-0001-6237-2502; Mendonça, Alexandre de ORCID: https://orcid.org/0000-0002-0488-1453; Tiraboschi, Pietro ORCID: https://orcid.org/0000-0002-2171-1720; Santana, Isabel ORCID: https://orcid.org/0000-0002-8114-9434; Gerhard, Alexander ORCID: https://orcid.org/0000-0002-8071-6062; Levin, Johannes ORCID: https://orcid.org/0000-0001-5092-4306; Sorbi, Sandro ORCID: https://orcid.org/0000-0002-0380-6670; Otto, Markus ORCID: https://orcid.org/0000-0003-4273-4267; Pasquier, Florence ORCID: https://orcid.org/0000-0001-9880-9788; Ducharme, Simon ORCID: https://orcid.org/0000-0002-7309-1113; Butler, Christopher ORCID: https://orcid.org/0000-0002-7502-9284; Ber, Isabelle Le ORCID: https://orcid.org/0000-0002-2508-5181; Finger, Elizabeth ORCID: https://orcid.org/0000-0003-4461-7427; Tartaglia, Maria Carmela ORCID: https://orcid.org/0000-0002-5944-8497; Masellis, Mario ORCID: https://orcid.org/0000-0002-6244-2096; Rowe, James B. ORCID: https://orcid.org/0000-0001-7216-8679; Synofzik, Matthis ORCID: https://orcid.org/0000-0002-2280-7273; Moreno, Fermin ORCID: https://orcid.org/0000-0001-5200-3164; Borroni, Barbara ORCID: https://orcid.org/0000-0001-9340-9814; Rademakers, Rosa ORCID: https://orcid.org/0000-0002-4049-0863; Rohrer, Jonathan Daniel ORCID: https://orcid.org/0000-0002-6155-8417 und Sánchez-Valle, Raquel ORCID: https://orcid.org/0000-0001-7750-896X
(2024):
Association of Initial Side of Brain Atrophy With Clinical Features and Disease Progression in Patients With GRN Frontotemporal Dementia.
In: Neurology, Bd. 103, Nr. 11, e209944
[PDF, 828kB]
Brendel, Matthias ORCID: https://orcid.org/0000-0002-9247-2843; Parvizi, Tandis; Gnörich, Johannes ORCID: https://orcid.org/0000-0003-1554-7765; Topfstedt, Christof Elias; Buerger, Katharina ORCID: https://orcid.org/0000-0002-5898-9953; Janowitz, Daniel ORCID: https://orcid.org/0009-0003-4090-547X; Rauchmann, Boris‐Stephan; Perneczky, Robert ORCID: https://orcid.org/0000-0003-1981-7435; Kurz, Carolin; Mehrens, Dirk ORCID: https://orcid.org/0000-0001-5114-8935; Kunz, Wolfgang G. ORCID: https://orcid.org/0000-0002-5021-1952; Kusche‐Palenga, Julia; Kling, Agnes Bernadette; Buchal, Antonia; Nestorova, Elizabet; Silvaieh, Sara; Wurm, Raphael; Traub‐Weidinger, Tatjana; Klotz, Sigrid; Regelsberger, Günther; Rominger, Axel; Drzezga, Alexander; Levin, Johannes ORCID: https://orcid.org/0000-0001-5092-4306; Stögmann, Elisabeth; Franzmeier, Nicolai ORCID: https://orcid.org/0000-0001-9736-2283 und Höglinger, Günter U. ORCID: https://orcid.org/0000-0001-7587-6187
(2024):
Aβ status assessment in a hypothetical scenario prior to treatment with disease‐modifying therapies: Evidence from 10‐year real‐world experience at university memory clinics.
In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Bd. 16, Nr. 4, e70031
[PDF, 586kB]
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Association of Body Mass Index and Parkinson Disease.
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Prediction of dementia using diffusion tensor MRI measures: the OPTIMAL collaboration.
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Determining the OPTIMAL DTI analysis method for application in cerebral small vessel disease.
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No substantial neurocognitive impact of COVID-19 across ages and disease severity. A multicenter biomarker study of SARS-CoV-2 positive and negative adult and pediatric patients with acute respiratory tract infections.
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Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease.
In: Science Translational Medicine, Bd. 11, Nr. 507, eaav6221
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Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease.
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Circulating biomarkers of immunity and inflammation, risk of Alzheimer’s disease, and hippocampal volume: a Mendelian randomization study.
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Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes.
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What Is the Best Mix of Population-Wide and High-Risk Targeted Strategies of Primary Stroke and Cardiovascular Disease Prevention?
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The global burden of neurological disorders: translating evidence into policy.
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Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies.
In: Molecular Psychiatry, Bd. 28, Nr. 10: S. 4438-4450
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(2020):
Patient-centered connectivity-based prediction of tau pathology spread in Alzheimer's disease.
In: Science Advances, Bd. 6, Nr. 48, abd1327
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(2018):
Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer’s disease.
In: Brain, Bd. 141: S. 1186-1200
Franzmeier, Nicolai; Hartmann, Julia; Taylor, Alexander N. W.; Araque-Caballero, Miguel A.; Simon-Vermot, Lee; Kambeitz-Ilankovic, Lana; Bürger, Katharina; Catak, Cihan; Janowitz, Daniel; Müller, Claudia; Ertl-Wagner, Birgit; Stahl, Robert; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Duering, Marco und Ewers, Michael
(2018):
The left frontal cortex supports reserve in aging by enhancing functional network efficiency.
In: Alzheimers Research & Therapy
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Franzmeier, Nicolai; Koutsouleris, Nikolaos; Benzinger, Tammie; Goate, Alison; Karch, Celeste M.; Fagan, Anne M.; McDade, Eric; Duering, Marco; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Levin, Johannes; Gordon, Brian A.; Lim, Yen Ying; Masters, Colin L.; Rossor, Martin; Fox, Nick C.; O'Connor, Antoinette; Chhatwal, Jasmeer; Salloway, Stephen; Danek, Adrian; Hassenstab, Jason; Schofield, Peter R.; Morris, John C.; Bateman, Randall J. und Ewers, Michael
(2020):
Predicting sporadic Alzheimer's disease progression via inherited Alzheimer's disease-informed machine-learning.
In: Alzheimer's and Dementia, Bd. 16, Nr. 3: S. 501-511
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(2021):
The BIN1 rs744373 Alzheimer's disease risk SNP is associated with faster A beta-associated tau accumulation and cognitive decline.
In: Alzheimers & Dementia, Bd. 18, Nr. 1: S. 103-115
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(2021):
The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.
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Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration.
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(2020):
Predicting sporadic Alzheimer's disease progression via inherited Alzheimer's disease‐informed machine‐learning.
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(20. August 2022):
Earlier Alzheimer’s disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading.
In: Nature Communications, Bd. 13
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(2022):
Cerebral small vessel disease burden and cognitive and functional outcomes after stroke: A multicenter prospective cohort study.
In: Alzheimer's & Dementia, Bd. 19, Nr. 4: S. 1152-1163
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Georgakis, Marios K.; Gill, Dipender; Webb, Alastair J. S.; Evangelou, Evangelos; Elliott, Paul; Sudlow, Cathie L. M.; Dehghan, Abbas; Malik, Rainer; Tzoulaki, Ioanna und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
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Genetically determined blood pressure, antihypertensive drug classes, and risk of stroke subtypes.
In: Neurology, Bd. 95, Nr. 4, E353-E361
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(2021):
Diabetes Mellitus, Glycemic Traits, and Cerebrovascular Disease A Mendelian Randomization Study.
In: Neurology, Bd. 96, Nr. 13, E1732-E1742
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Georgakis, Marios K.; Laan, Sander W. van der; Asare, Yaw; Mekke, Joost M.; Haitjema, Saskia; Schoneveld, Arjan H.; de Jager, Saskia C. A.; Nurmohamed, Nick S.; Kroon, Jeffrey; Stroes, Erik S. G.; Kleijn, Dominique P. V. de; Borst, Gert J. de; Maegdefessel, Lars; Soehnlein, Oliver; Pasterkamp, Gerard und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2021):
Monocyte-Chemoattractant Protein-1 Levels in Human Atherosclerotic Lesions Associate With Plaque Vulnerability.
In: Arteriosclerosis Thrombosis and Vascular Biology, Bd. 41, Nr. 6: S. 2038-2048
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Genetic Architecture of Stroke of Undetermined Source: Overlap with Known Stroke Etiologies and Associations with Modifiable Risk Factors.
In: Annals of Neurology, Bd. 91, Nr. 5: S. 640-651
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Association of Circulating Monocyte Chemoattractant Protein-1 Levels With Cardiovascular Mortality A Meta-analysis of Population-Based Studies.
In: Jama Cardiology, Bd. 6, Nr. 5: S. 587-592
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(Januar 2019):
Genetically Determined Levels of Circulating Cytokines and Risk of Stroke. Role of Monocyte Chemoattractant Protein-1.
In: Circulation, Bd. 139, Nr. 2
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Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects.
In: Circulation, Bd. 140, Nr. 4: S. 270-279
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Towards multicenter β-amyloid PET imaging in mouse models. A triple scanner head-to-head comparison.
In: NeuroImage, Bd. 297, 120748
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Population impact of different hypertension management guidelines based on the prospective population-based Heinz Nixdorf Recall study.
In: BMJ Open, Bd. 11, Nr. 2, e039597
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(2019):
Cardiovascular Risk and Atherosclerosis Progression in Hypertensive Persons Treated to Blood Pressure Targets.
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Probing intracellular potassium dynamics in neurons with the genetically encoded sensor lc-LysM GEPII 1.0 in vitro and in vivo.
In: Scientific Reports, Bd. 14, 13753
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(2019):
Preventing dementia by preventing stroke: The Berlin Manifesto.
In: Alzheimer's & Dementia, Bd. 15, Nr. 7: S. 961-984
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Special topic section: linkages among cerebrovascular, cardiovascular, and cognitive disorders: Preventing dementia by preventing stroke: The Berlin Manifesto.
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Software-assisted structured reporting and semi-automated TNM classification for NSCLC staging in a multicenter proof of concept study.
In: Insights into Imaging, Bd. 15, 258
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(26. Mai 2021):
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
In: Journal of Experimental Medicine, Bd. 218, Nr. 8, e20202411
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A novel prediction score determining individual clinical outcome 3 months after juvenile stroke. (PREDICT-score).
In: Journal of Neurology, Bd. 271, Nr. 9: S. 6238-6246
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Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer’s disease.
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Definition and diagnosis of Parkinson’s disease. Guideline “Parkinson’s disease” of the German Society of Neurology.
In: Journal of Neurology, Bd. 271: S. 7102-7119
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Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits.
In: Molecular Neurodegeneration, Bd. 19, 50
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Pharmacotherapy of motor symptoms in early and mid-stage Parkinson’s disease. Guideline “Parkinson’s disease” of the German Society of Neurology.
In: Journal of Neurology, Bd. 271, Nr. 11: S. 7071-7101
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Alzheimer-Demenz bei Menschen mit einem Down-Syndrom. Ergebnisse leitfadengestützter Expert :inneninterviews zu Versorgungsdefiziten in Diagnostik und Therapie sowie Lösungsansätzen.
In: Zeitschrift für Gerontologie und Geriatrie [Forthcoming]
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(2024):
Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis.
In: Immunity, Bd. 57, Nr. 11: S. 2651-2668
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(2024):
Genotype-specific effects of elamipretide in patients with primary mitochondrial myopathy: a post hoc analysis of the MMPOWER-3 trial.
In: Orphanet Journal of Rare Diseases, Bd. 19, 431
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GFAP and NfL as fluid biomarkers for clinical disease severity and disease progression in multiple system atrophy (MSA).
In: Journal of Neurology, Bd. 271: S. 6991-6999
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T cell-mediated microglial activation triggers myelin pathology in a mouse model of amyloidosis.
In: Nature Neuroscience, Bd. 27, Nr. 8: S. 1468-1474
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(2020):
Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke.
In: Stroke, Bd. 51, Nr. 8: S. 2454-2463
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(2024):
Panel stacking is a threat to consensus statement validity.
In: Journal of Clinical Epidemiology, Bd. 173, 111428
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Combining array tomography with electron tomography provides insights into leakiness of the blood-brain barrier in mouse cortex.
In: eLife, Bd. 12, RP90565
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Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting.
In: Nature Communications, Bd. 11, Nr. 1, 5981
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Complicated Carotid Artery Plaques as a Cause of Cryptogenic Stroke.
In: Journal of the American College of Cardiology, Bd. 76, Nr. 19: S. 2212-2222
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The EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases (TREAT-SVDs) trial: Study protocol for a randomised crossover trial.
In: European Stroke Journal, Bd. 8, Nr. 1: S. 387-397
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(2023):
Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial.
In: Lancet Neurology, Bd. 22, Nr. 11: S. 991-1004
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Pathways linking aging and atheroprotection in Mif‐deficient atherosclerotic mice.
In: The FASEB Journal, Bd. 37, Nr. 3
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Inferring histology-associated gene expression gradients in spatial transcriptomic studies.
In: Nature Communications, Bd. 15, 7280
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PET/CT imaging of differentiated and medullary thyroid carcinoma using the novel SSTR-targeting peptide [18F]SiTATE – first clinical experiences.
In: European Journal of Nuclear Medicine and Molecular Imaging [Forthcoming]
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Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Atherosclerotic Plaques.
In: Circulation-Genomic and Precision Medicine, Bd. 11, Nr. 9, e002115
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PET imaging of microglia in Alzheimer's disease using copper-64 labeled TREM2 antibodies.
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European Stroke Organisation (ESO) standard operating procedure for the preparation and publishing of guidelines.
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Stroke Etiology Modifies the Effect of Endovascular Treatment in Acute Stroke.
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(2024):
Soluble form of Lingo2, an autism spectrum disorder-associated molecule, functions as an excitatory synapse organizer in neurons.
In: Translational Psychiatry, Bd. 14, 448
[PDF, 2MB]
Yousefi, Elham; Gewily, Mohamed; König, Franz; Höglinger, Günter ORCID: https://orcid.org/0000-0001-7587-6187; Hopfner, Franziska ORCID: https://orcid.org/0000-0001-6524-0281; Karlsson, Mats O.; Ristl, Robin; Zehetmayer, Sonja und Posch, Martin
(2024):
Efficiency of multivariate tests in trials in progressive supranuclear palsy.
In: Scientific Reports, Bd. 14, 25581
[PDF, 2MB]
Yuan, Shuai; Burgess, Stephen; Laffan, Mike; Mason, Amy M.; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Gill, Dipender und Larsson, Susanna C.
(2021):
Genetically Proxied Inhibition of Coagulation Factors and Risk of Cardiovascular Disease: A Mendelian Randomization Study.
In: Gesundheitswesen, Bd. 10, Nr. 8, e019644
[PDF, 933kB]
Zatcepin, Artem ORCID: https://orcid.org/0000-0002-0224-088X; Gnörich, Johannes ORCID: https://orcid.org/0000-0003-1554-7765; Rauchmann, Boris-Stephan ORCID: https://orcid.org/0000-0003-4547-6240; Bartos, Laura M.; Wagner, Stephan; Franzmeier, Nicolai ORCID: https://orcid.org/0000-0001-9736-2283; Malpetti, Maura ORCID: https://orcid.org/0000-0001-8923-9656; Xiang, Xianyuan; Shi, Yuan; Parhizkar, Samira; Grosch, Maximilian; Wind-Mark, Karin; Kunte, Sebastian T.; Beyer, Leonie; Meyer, Carolin; Brösamle, Desirée; Wendeln, Ann-Christin; Osei-Sarpong, Collins; Heindl, Steffanie; Liesz, Arthur ORCID: https://orcid.org/0000-0002-9069-2594; Stoecklein, Sophia; Biechele, Gloria; Finze, Anika; Eckenweber, Florian; Lindner, Simon ORCID: https://orcid.org/0009-0007-4379-4436; Rominger, Axel ORCID: https://orcid.org/0000-0002-1954-736X; Bartenstein, Peter ORCID: https://orcid.org/0009-0005-0734-4994; Willem, Michael; Tahirovic, Sabina ORCID: https://orcid.org/0000-0003-4403-9559; Herms, Jochen; Buerger, Katharina; Simons, Mikael ORCID: https://orcid.org/0000-0001-5329-192X; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Rupprecht, Rainer ORCID: https://orcid.org/0000-0003-2939-9062; Riemenschneider, Markus J.; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Beyer, Marc; Neher, Jonas J.; Paeger, Lars; Levin, Johannes ORCID: https://orcid.org/0000-0001-5092-4306; Höglinger, Günter U. ORCID: https://orcid.org/0000-0001-7587-6187; Perneczky, Robert ORCID: https://orcid.org/0000-0003-1981-7435; Ziegler, Sibylle I. ORCID: https://orcid.org/0000-0002-5321-4817 und Brendel, Matthias ORCID: https://orcid.org/0000-0002-9247-2843
(2024):
Regional desynchronization of microglial activity is associated with cognitive decline in Alzheimer’s disease.
In: Molecular Neurodegeneration, Bd. 19, 64
[PDF, 6MB]
Zellner, Andreas; Müller, Stephan A.; Lindner, Barbara; Beaufort, Nathalie; Rozemuller, Annemieke J. M.; Arzberger, Thomas; Gassen, Nils C.; Lichtenthaler, Stefan F.; Kuster, Bernhard; Haffner, Christof und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2022):
Proteomic profiling in cerebral amyloid angiopathy reveals an overlap with CADASIL highlighting accumulation of HTRA1 and its substrates.
In: Acta neuropathologica communications, Bd. 10, 6
[PDF, 37MB]
Zellner, Andreas; Scharrer, Eva; Arzberger, Thomas; Oka, Chio; Domenga-Denier, Valerie; Joutel, Anne; Lichtenthaler, Stefan F.; Müller, Stephan A.; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X und Haffner, Christof
(2018):
CADASIL brain vessels show a HTRA1 loss-of-function profile.
In: Acta Neuropathologica, Bd. 136, Nr. 1: S. 111-125
Zheng, Lukai ORCID: https://orcid.org/0000-0003-1328-2791; Rubinski, Anna; Denecke, Jannis ORCID: https://orcid.org/0000-0003-4777-2238; Luan, Ying; Smith, Ruben; Strandberg, Olof; Stomrud, Erik; Ossenkoppele, Rik; Svaldi, Diana Otero; Higgins, Ixavier Alonzo; Shcherbinin, Sergey; Pontecorvo, Michael J.; Hansson, Oskar ORCID: https://orcid.org/0000-0001-8467-7286; Franzmeier, Nicolai ORCID: https://orcid.org/0000-0001-9736-2283 und Ewers, Michael ORCID: https://orcid.org/0000-0001-5231-1714
(2023):
Combined Connectomics, MAPT Gene Expression, and Amyloid Deposition to Explain Regional Tau Deposition in Alzheimer Disease.
In: Annals of Neurology
[PDF, 2MB]
Zhou, Yuxi ORCID: https://orcid.org/0009-0001-5641-235X; Wang, Xin; Yin, Wen; Li, Yan; Guo, Yunlu ORCID: https://orcid.org/0000-0001-6073-5947; Chen, Chen; Boltze, Johannes; Liesz, Arthur ORCID: https://orcid.org/0000-0002-9069-2594; Sparwasser, Tim; Wen, Daxiang; Yu, Weifeng und Li, Peiying ORCID: https://orcid.org/0000-0002-5721-9914
(2024):
Perioperative stroke deteriorates white matter integrity by enhancing cytotoxic CD8+ T‐cell activation.
In: CNS Neuroscience & Therapeutics, Bd. 30, Nr. 7, e14747
[PDF, 36MB]
Zietemann, Vera; Georgakis, Marios K.; Dondaine, Thibaut; Müller, Claudia; Mendyk, Anne-Marie; Kopczak, Anna; Henon, Hilde; Bombois, Stephanie; Wollenweber, Frank Arne; Bordet, Regis und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2018):
Early MoCA predicts long-term cognitive and functional outcome and mortality after stroke.
In: Neurology, Bd. 91, Nr. 20, E1838-E1850
[PDF, 738kB]
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