Anzahl der Publikationen: 243
Zeitschriftenartikel
Michl, Marlies; Taverna, Francesco; Woischke, Christine; Li, Pan; Klauschen, Frederick; Kirchner, Thomas; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Stahler, Arndt; Herold, Tobias Marcus; Jurinovic, Vindi; Engel, Jutta; Kumbrink, Jörg ORCID: https://orcid.org/0000-0003-4633-4105 und Neumann, Jens
(2024):
Identification of a gene expression signature associated with brain metastasis in colorectal cancer.
In: Clinical and Translational Oncology, Bd. 26: S. 1886-1895
[PDF, 848kB]
Zhang, Danmei ORCID: https://orcid.org/0000-0001-6048-4711; Westphalen, Christoph Benedikt; Quante, Michael; Waldschmidt, Dirk T.; Held, Swantje ORCID: https://orcid.org/0000-0002-1344-9056; Kütting, Fabian; Dorman, Klara; Heinrich, Kathrin ORCID: https://orcid.org/0000-0003-3580-2313; Weiss, Lena; Boukovala, Myrto; Haas, Michael; Boeck, Stefan; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321 und Probst, Victoria
(2024):
Gemcitabine and nab-paclitaxel combined with afatinib in metastatic pancreatic cancer. Results of a phase 1b clinical trial.
In: European Journal of Cancer, Bd. 201, 113926
[PDF, 1MB]
Boukovala, Myrto; Modest, Dominik Paul; Ricard, Ingrid; Fischer von Weikersthal, Ludwig; Decker, Thomas; Vehling-Kaiser, Ursula; Uhlig, Jens; Schenk, Michael; Freiberg-Richter, Jens; Peuser, Bettina; Denzlinger, Claudio; Peveling Genannt Reddemann, C.; Graeven, Ullrich ORCID: https://orcid.org/0000-0001-6082-7710; Schuch, Gunter ORCID: https://orcid.org/0000-0001-7503-457X; Schwaner, Ingo ORCID: https://orcid.org/0000-0001-8865-7282; Heinrich, Kathrin ORCID: https://orcid.org/0000-0003-3580-2313; Neumann, Jens; Jung, Andreas; Held, Swantje ORCID: https://orcid.org/0000-0002-1344-9056; Stintzing, Sebastian ORCID: https://orcid.org/0000-0002-3297-5801; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321 und Michl, Marlies ORCID: https://orcid.org/0000-0002-4198-3627
(2024):
Evaluation of the inflammation-based modified Glasgow Prognostic Score (mGPS) as a prognostic and predictive biomarker in patients with metastatic colorectal cancer receiving first-line chemotherapy: a post hoc analysis of the randomized phase III XELAVIRI trial (AIO KRK0110).
In: ESMO Open, Bd. 9, Nr. 5, 103374
[PDF, 725kB]
Zhang, Danmei ORCID: https://orcid.org/0000-0001-6048-4711; Dorman, Klara; Westphalen, Christoph Benedikt ORCID: https://orcid.org/0000-0002-5310-3754; Haas, Michael; Ormanns, Steffen ORCID: https://orcid.org/0000-0002-0754-9034; Neumann, Jens; Seidensticker, Max ORCID: https://orcid.org/0000-0002-2481-5410; Ricke, Jens; De Toni, Enrico N. ORCID: https://orcid.org/0000-0002-8101-8207; Klauschen, Frederick; Algül, Hana; Reisländer, Timo; Boeck, Stefan und Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321
(2024):
Unresectable biliary tract cancer: Current and future systemic therapy.
In: European Journal of Cancer, Bd. 203, 114046
[PDF, 8MB]
Issels, Rolf D. ORCID: https://orcid.org/0000-0002-3494-6561; Böck, Stefan; Pelzer, Uwe; Mansmann, Ulrich ORCID: https://orcid.org/0000-0002-9955-8906; Ghadjar, Pirus; Lindner, Lars H. ORCID: https://orcid.org/0000-0003-3708-8264; Albertsmeier, Markus ORCID: https://orcid.org/0000-0002-5028-5062; Angele, Martin K.; Schmidt, Michael ORCID: https://orcid.org/0000-0001-5898-9323; Xu, Yujun ORCID: https://orcid.org/0000-0002-8487-7584; Bahra, Marcus; Pratschke, Johann; Schoenberg, Michael; Thasler, Wolfgang E.; Salat, Christoph; Stoetzer, Oliver J.; Knoefel, Wolfram T.; Graf, Dirk; Wessalowski, Rüdiger; Keitel-Anselmino, Verena; Koenigsrainer, Alfred; Bitzer, Michael ORCID: https://orcid.org/0000-0002-4463-8263; Zips, Daniel; Bamberg, Michael; Fietkau, Rainer; Ott, Oliver; Kawecki, Maciej ORCID: https://orcid.org/0000-0001-7858-6214; Wyrwicz, Lucjan; Rutkowski, Piotr; Rentsch, Markus; Ababei, Juliana; Reichardt, Peter; Rigamonti, Marco; Weber, Bernhard; Abdel-Rahman, Sultan; Tschoep–Lechner, Katharina; Jauch, Karl-Walter; Bruns, Christiane J.; Oettle, Helmut; Bergwelt-Baildon, Michael von; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321 und Werner, Jens
(2023):
Regional hyperthermia with cisplatin added to gemcitabine versus gemcitabine in patients with resected pancreatic ductal adenocarcinoma: The HEAT randomised clinical trial.
In: European Journal of Cancer (EJC), Bd. 181: S. 155-165
Guenther, Michael; Surendran, Sai Agash; Haas, Michael; Heinemann, Volker; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Engel, Jutta; Werner, Jens; Boeck, Stefan ORCID: https://orcid.org/0000-0002-1922-2127 und Ormanns, Steffen ORCID: https://orcid.org/0000-0002-0754-9034
(2023):
TPX2 expression as a negative predictor of gemcitabine efficacy in pancreatic cancer.
In: British Journal of Cancer, Bd. 129: S. 175-182
[PDF, 1MB]
Weiss, L.; Heinrich, K.; Zhang, D.; Dorman, K.; Rühlmann, K.; Hasselmann, K.; Klauschen, F.; Kumbrink, J.; Jung, A.; Rudelius, M.; Mock, A.; Ormanns, Steffen ORCID: https://orcid.org/0000-0002-0754-9034; Kunz, W. G.; Roessler, D.; Beyer, G.; Corradini, S.; Heinzerling, L.; Haas, M.; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Boeck, S.; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321 und Westphalen, C. B. ORCID: https://orcid.org/0000-0002-5310-3754
(2023):
Cancer of unknown primary (CUP) through the lens of precision oncology: a single institution perspective.
In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 11: S. 8225-8234
[PDF, 623kB]
Zhang, Danmei; Dorman, Klara; Heinrich, Kathrin; Weiss, Lena; Boukovala, Myrto; Haas, Michael; Greif, Philipp A.; Ziemann, Frank; Beyer, Georg; Roessler, Daniel; Goni, Elisabetta; Renz, Bernhard; D’Haese, Jan G.; Kunz, Wolfgang G.; Seidensticker, Max ORCID: https://orcid.org/0000-0002-2481-5410; Corradini, Stefanie ORCID: https://orcid.org/0000-0001-8709-7252; Niyazi, Maximilian; Ormanns, Steffen ORCID: https://orcid.org/0000-0002-0754-9034; Kumbrink, Jörg; Jung, Andreas; Mock, Andreas; Rudelius, Martina; Klauschen, Frederick; Werner, Jens; Mayerle, Julia ORCID: https://orcid.org/0000-0002-3666-6459; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Boeck, Stefan; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321 und Westphalen, C. Benedikt ORCID: https://orcid.org/0000-0002-5310-3754
(2023):
A Retrospective Analysis of Biliary Tract Cancer Patients Presented to the Molecular Tumor Board at the Comprehensive Cancer Center Munich.
In: Targeted Oncology, Bd. 18, Nr. 5: S. 767-776
[PDF, 864kB]
Berclaz, Luc M.; Burkhard-Meier, Anton; Lange, Philipp; Di Gioia, Dorit; Schmidt, Michael; Knösel, Thomas ORCID: https://orcid.org/0000-0002-1822-0197; Klauschen, Frederick; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321; Greif, Philipp A.; Westphalen, C. Benedikt ORCID: https://orcid.org/0000-0002-5310-3754; Heinrich, Kathrin und Lindner, Lars H.
(2023):
Implementing precision oncology for sarcoma patients: the CCCLMUmolecular tumor board experience.
In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 15: S. 13973-13983
[PDF, 823kB]
Weiss, Lena; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321; Fischer, Laura E.; Gieseler, Frank; Hoehler, Thomas; Mayerle, Julia ORCID: https://orcid.org/0000-0002-3666-6459; Quietzsch, Detlef; Reinacher-Schick, Anke; Schenk, Michael; Seipelt, Gernot; Siveke, Jens T.; Stahl, Michael; Vehling-Kaiser, Ursula; Waldschmidt, Dirk T.; Dorman, Klara; Zhang, Danmei; Westphalen, C. Benedikt ORCID: https://orcid.org/0000-0002-5310-3754; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Boeck, Stefan und Haas, Michael ORCID: https://orcid.org/0000-0001-6745-7177
(2023):
Three-month life expectancy as inclusion criterion for clinical trials in advanced pancreatic cancer: is it really a valid tool for patient selection?
In: Clinical and Translational Oncology, Bd. 26, Nr. 5: S. 1268-1272
[PDF, 430kB]
Dorman, Klara; Zhang, Danmei; Heinrich, Kathrin; Reeh, Laurens; Weiss, Lena; Haas, Michael; Beyer, Georg; Rössler, Daniel; Goni, Elisabetta; Renz, Bernhard W.; D’Haese, Jan G.; Kunz, Wolfgang G.; Seidensticker, Max ORCID: https://orcid.org/0000-0002-2481-5410; Corradini, Stefanie; Niyazi, Maximilian; Ormanns, Steffen ORCID: https://orcid.org/0000-0002-0754-9034; Kumbrink, Jörg ORCID: https://orcid.org/0000-0003-4633-4105; Jung, Andreas; Klauschen, Frederick; Werner, Jens; Mayerle, Julia ORCID: https://orcid.org/0000-0002-3666-6459; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Boeck, Stefan; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321 und Westphalen, C. Benedikt ORCID: https://orcid.org/0000-0002-5310-3754
(2023):
Precision Oncology in Pancreatic Cancer: Experiences and Challenges of the CCCMunichLMU Molecular Tumor Board.
In: Targeted Oncology, Bd. 18, Nr. 2: S. 257-267
[PDF, 1MB]
Tufman, Amanda; Schneiderbauer, Sophie; Walter, Julia; Resuli, Blerina; Kauffmann-Guerrero, Diego; Mümmler, Carlo; Mertsch, Pontus; Götschke, Jeremias; Kovács, Julia; Manapov, Farkhad; Schneider, Christian; Sellmer, Laura; Arnold, Paola; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321; Behr, Jürgen ORCID: https://orcid.org/0000-0002-9151-4829 und Nasseh, Daniel
(2023):
Early mortality in German patients with lung cancer: risk factors associated with 30-and 60-day mortality.
In: Clinical and Experimental Medicine, Bd. 23, Nr. 8: S. 5183-5190
[PDF, 744kB]
Pretzsch, Elise; Heinemann, Volker; Stintzing, Sebastian; Bender, Andreas; Chen, Shuo; Holch, Julian Walter; Hofmann, Felix Oliver; Ren, Haoyu; Bösch, Florian; Küchenhoff, Helmut; Werner, Jens und Angele, Martin Konrad
(14. November 2022):
EMT-Related Genes Have No Prognostic Relevance in Metastatic Colorectal Cancer as Opposed to Stage II/III: Analysis of the Randomised, Phase III Trial FIRE-3 (AIO KRK 0306; FIRE-3).
In: Cancers, Bd. 14, Nr. 22
[PDF, 650kB]
Guenther, Michael; Gil, Lina; Surendran, Sai Agash; Palm, Melanie Alexandra; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Mayerle, Julia; Engel, Jutta; Werner, Jens; Boeck, Stefan und Ormanns, Steffen ORCID: https://orcid.org/0000-0002-0754-9034
(2022):
Bacterial Lipopolysaccharide as a Negative Predictor of Adjuvant Gemcitabine Efficacy in Pancreatic Cancer.
In: JNCI Cancer Spectrum, Bd. 6, Nr. 3, pkac039
[PDF, 555kB]
Hofmann, Felix O. ORCID: https://orcid.org/0000-0002-6913-2429; Heinemann, Volker; D'Anastasi, Melvin; Gesenhues, Alena B.; Hesse, Nina; Weikersthal, Ludwig Fischer von; Decker, Thomas; Kiani, Alexander; Moehler, Markus; Kaiser, Florian; Heintges, Tobias; Kahl, Christoph; Kullmann, Frank; Scheithauer, Werner; Link, Hartmut; Modest, Dominik P.; Stintzing, Sebastian und Holch, Julian W.
(2022):
Standard diametric versus volumetric early tumor shrinkage as a predictor of survival in metastatic colorectal cancer: subgroup findings of the randomized, open-label phase III trial FIRE-3/AIO KRK-0306.
In: European Radiology, Bd. 33, Nr. 2: S. 1174-1184
[PDF, 2MB]
Dorman, Klara; Gerckens, Miriam; Kruger, Stephan; Krueger, Kimberly; Mayer, Zsuzsanna; Rupp, Alexander; Zhang, Danmei; Weiss, Lena; Westphalen, C. Benedikt; Haas, Michael; Guenther, Michael; Ormanns, Steffen; Klawonn, Frank; Werner, Jens; Bergwelt-Baildon, Michael von; Heinemann, Volker; Böck, Stefan und Holdenrieder, Stefan
(2022):
Serum biomarker panel diagnostics in pancreatic ductal adenocarcinoma: the clinical utility of soluble interleukins, IFN-gamma, TNF-alpha and PD-1/PD-L1 in comparison to established serum tumor markers.
In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 6: S. 2463-2474
[PDF, 1MB]
Heinrich, Kathrin; Miller-Phillips, Lisa; Ziemann, Frank; Hasselmann, Korbinian; Rühlmann, Katharina; Flach, Madeleine; Biro, Dorottya; Bergwelt-Baildon, Michael von; Holch, Julian; Herold, Tobias; Baumgarten, Louisa von; Greif, Philip A. ORCID: https://orcid.org/0000-0002-3744-7936; Jeremias, Irmela; Wuerstlein, Rachel; Casuscelli, Jozefina; Spitzweg, Christine; Seidensticker, Max; Renz, Bernhard; Corradini, Stefanie; Baumeister, Philipp; Goni, Elisabetta; Tufman, Amanda; Jung, Andreas; Kumbrink, Jörg; Kirchner, Thomas; Klauschen, Frederick; Metzeler, Klaus H.; Heinemann, Volker und Westphalen, C. Benedikt ORCID: https://orcid.org/0000-0002-5310-3754
(2022):
Lessons learned: the first consecutive 1000 patients of the CCCMunich(LMU) Molecular Tumor Board.
In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 5: S. 1905-1915
[PDF, 728kB]
Torlot, Lucien; Jarzab, Anna; Albert, Johanna; Pok-Udvari, Agnes; Stahler, Arndt; Holch, Julian Walter; Gerlinger, Marco; Heinemann, Volker; Klauschen, Frederick; Kirchner, Thomas; Kumbrink, Jörg; Küster, Bernhard und Jung, Andreas ORCID: https://orcid.org/0000-0001-5270-9108
(2022):
Proteomics uncover EPHA2 as a potential novel therapeutic target in colorectal cancer cell lines with acquired cetuximab resistance.
In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 2: S. 669-682
[PDF, 2MB]
Fey, Theres; Erickson, Nicole ORCID: https://orcid.org/0000-0002-0473-7689; Stahler, Arndt; Muenchhoff, Maximilian; Keppler, Oliver T.; Rühlmann, Katharina; Krauss-Pfeiffer, Gabriele; Steinberg, Hannah; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Khatamzas, Elham; Seynstahl, Sarah; Casuscelli, Jozefina; Markwardt, Daniel; Forstpointner, Roswitha; Schinkoethe, Timo; Bergwelt-Baildon, Michael von und Heinemann, Volker
(2022):
Should routine risk reduction procedures for the prevention and control of pandemics become a standard in all oncological outpatient clinics? The prospective COVID-19 cohort study: protect-CoV.
In: Medical Oncology, Bd. 39, Nr. 6
[PDF, 678kB]
Tamalunas, Alexander ORCID: https://orcid.org/0000-0002-4659-2262; Schott, Melanie ORCID: https://orcid.org/0000-0002-6477-5636; Ivanova, Troya ORCID: https://orcid.org/0000-0002-1073-4150; Rodler, Severin ORCID: https://orcid.org/0000-0002-7600-6535; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321; Stief, Christian G. ORCID: https://orcid.org/0000-0003-3291-9460 und Casuscelli, Jozefina ORCID: https://orcid.org/0000-0002-9899-1986
(2022):
Strategies to successfully prevent COVID-19 outbreak in vulnerable uro-oncology patient population.
In: Infection, Bd. 50, Nr. 5: S. 1131-1137
[PDF, 909kB]
Fischer, Laura E. ORCID: https://orcid.org/0000-0001-8752-5827; Stintzing, Sebastian; Weikersthal, Ludwig Fischer von; Modest, Dominik P.; Decker, Thomas; Kiani, Alexander ORCID: https://orcid.org/0000-0002-2494-4087; Kaiser, Florian; Al-Batran, Salah-Eddin; Heintges, Tobias; Lerchenmüller, Christian; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Stauch, Martina; Scheithauer, Werner; Giessen-Jung, Clemens; Uhlig, Jens; Peuser, Bettina; Denzlinger, Claudio; Stahler, Arndt; Weiss, Lena; Heinrich, Kathrin; Held, Swantje; Jung, Andreas; Kirchner, Thomas und Heinemann, Volker
(2022):
Efficacy of FOLFIRI plus cetuximab vs FOLFIRI plus bevacizumab in 1st-line treatment of older patients with RAS wild-type metastatic colorectal cancer: an analysis of the randomised trial FIRE-3.
In: British Journal of Cancer, Bd. 127, Nr. 5: S. 836-843
[PDF, 788kB]
Kumbrink, Jorg; Bohlmann, Lisa; Mamlouk, Soulafa; Redmer, Torben; Peilstocker, Daniela; Li, Pan; Lorenzen, Sylvie; Alguel, Hana; Kasper, Stefan; Hempel, Dirk; Kaiser, Florian; Michl, Marlies; Bartsch, Harald; Neumann, Jens; Klauschen, Frederick; Bergwelt-Baildon, Michael von; Modest, Dominik Paul; Stahler, Arndt; Stintzing, Sebastian; Jung, Andreas; Kirchner, Thomas; Schäfer, Reinhold; Heinemann, Volker und Holch, Julian W.
(2022):
Serial Analysis of Gene Mutations and Gene Expression during First-Line Chemotherapy against Metastatic Colorectal Cancer: Identification of Potentially Actionable Targets within the Multicenter Prospective Biomarker Study REVEAL.
In: Cancers, Bd. 14, Nr. 15
[PDF, 4MB]
Arndt, Volker; Doege, Daniela; Froehling, Stefan; Albers, Peter; Alguel, Hana; Bargou, Ralf; Bokemeyer, Carsten; Bornhaeuser, Martin; Brandts, Christian H.; Brossart, Peter; Brucker, Sara Yvonne; Bruemmendorf, Tim H.; Doehner, Hartmut; Gattermann, Norbert; Hallek, Michael; Heinemann, Volker; Keilholz, Ulrich; Kindler, Thomas; Levetzow, Cornelia von; Lordick, Florian; Neumann, Ulf Peter; Peters, Christoph; Schadendorf, Dirk; Stilgenbauer, Stephan; Zander, Thomas; Zips, Daniel; Braun, Delia; Seufferlein, Thomas; Nettekoven, Gerd und Baumann, Michael
(2022):
Cancer care in German centers of excellence during the first 2 years of the COVID-19 pandemic.
In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 2: S. 913-919
Hofheinz, Ralf; Arnold, Dirk; Fichtner-Feigl, Stefan; Fokas, Emmanouil; Folprecht, Gunnar; Geissler, Michael; Ghadimi, Michael; Hegewisch-Becker, Susanne; Heinemann, Volker; Kasper-Virchow, Stefan; Kubicka, Stefan; Modest, Dominik Paul; Piso, Pompilio; Reinacher-Schick, Anke; Rodel, Claus-Michael; Seufferlein, Thomas; Stein, Alexander und Stintzing, Sebastian
(2022):
Arbeitsgruppen zu kolorektalen Tumoren der AIO, der ACO und der ARO – „past, present, and future“.
In: Onkologe, Bd. 28, Nr. SUPPL 1: S. 44-49
Arai, Hiroyuki; Millstein, Joshua; Yang, Yan; Stintzing, Sebastian; Wang, Jingyuan; Battaglin, Francesca; Kawanishi, Natsuko; Jayachandran, Priya; Soni, Shivani; Zhang, Wu; Heinemann, Volker und Lenz, Heinz-Josef
(2022):
Germline Polymorphisms in Genes Involved in the Antioxidant System Predict the Efficacy of Cetuximab in Metastatic Colorectal Cancer Patients Enrolled in FIRE-3 Trial.
In: Clinical Colorectal Cancer, Bd. 21, Nr. 3: S. 259-266
Papamichael, Demetris; Lopes, Guilherme S.; Olswold, Curt L.; Douillard, Jean-Yves; Adams, Richard A.; Maughan, Timothy S.; Cutsem, Eric van; Venook, Alan P.; Lenz, Heinz-Josef; Heinemann, Volker; Kaplan, Richard; Bokemeyer, Carsten; Chibaudel, Benoist; Grothey, Axel; Yoshino, Takayuki; Zalcberg, John; De Gramont, Aimery und Shi, Qian
(2022):
Efficacy of anti-epidermal growth factor receptor agents in patients with RAS wild-type metastatic colorectal cancer = 70 years.
In: European Journal of Cancer, Bd. 163: S. 1-15
Wang, Jingyuan; Xiao, Yi; Loupakis, Fotios; Stintzing, Sebastian; Yang, Yan; Arai, Hiroyuki; Battaglin, Francesca; Kawanishi, Natsuko; Jayachandran, Priya; Soni, Shivani; Zhang, Wu; Mancao, Christoph; Cremolini, Chiara; Liu, Tianshu; Heinemann, Volker; Falcone, Alfredo; Shen, Lin; Millstein, Joshua und Lenz, Heinz-Josef
(2022):
Genetic variants involved in the cGAS-STING pathway predict outcome in patients with metastatic colorectal cancer: Data from FIRE-3 and TRIBE trials.
In: European Journal of Cancer, Bd. 172: S. 22-30
Stahler, Arndt; Modest, Dominik P.; Fischer von Weikersthal, Ludwig; Kaiser, Florian; Decker, Thomas; Held, Swantje; Graeven, Ullrich; Schwaner, Ingo; Denzlinger, Claudio; Schenk, Michael; Kurreck, Annika; Heinrich, Kathrin; Giessen-Jung, Clemens; Neumann, Jens; Kirchner, Thomas; Jung, Andreas; Stintzing, Sebastian und Heinemann, Volker
(2022):
First-line fluoropyrimidine plus bevacizumab followed by irinotecan-escalation versus initial fluoropyrimidine, irinotecan and bevacizumab in patients with metastatic colorectal cancer - Final survival and per-protocol analysis of the randomised XELAVIRI trial (AIO KRK 0110).
In: European Journal of Cancer, Bd. 173: S. 194-203
Sommerhauser, Greta; Kurreck, Annika; Beck, Alexander; Fehrenbach, Uli; Karthaus, Meinolf; Fruehauf, Stefan; Graeven, Ullrich; Mueller, Lothar; Koenig, Alexander O.; Weikersthal, Ludwig F. v.; Goekkurt, Eray; Haas, Siegfried; Stahler, Arndt; Heinemann, Volker; Held, Swantje; Alig, Annabel H. S.; Kasper, Stefan; Stintzing, Sebastian; Trarbach, Tanja und Modest, Dominik P.
(2022):
Depth of response of induction therapy and consecutive maintenance treatment in patients with RAS wild-type metastatic colorectal cancer: An analysis of the PanaMa trial (AIO KRK 0212).
In: European Journal of Cancer, Bd. 178: S. 37-48
Unterrainer, Marcus; Deroose, Christophe M.; Herrmann, Ken; Moehler, Markus; Blomqvist, Lennart; Cannella, Roberto; Caramella, Caroline; Caruso, Damiano; Chouhan, Manil D.; Denecke, Timm; De la Pinta, Carolina; De Geus-Oei, Lioe-Fee; Dulskas, Audrius; Eisenblatter, Michel; Foley, Kieran G.; Gourtsoyianni, Sofia; Lecouvet, Frederic E.; Lopci, Egesta; Maas, Monique; Obmann, Markus M.; Oprea-Lager, Daniela E.; Verhoeff, Joost J. C.; Santiago, Ines; Terraz, Sylvain; D'Anastasi, Melvin; Regge, Daniele; Laghi, Andrea; Beets-Tan, Regina G. H.; Heinemann, Volker; Lordick, Florian; Smyth, Elizabeth C.; Ricke, Jens und Kunz, Wolfgang G.
(2022):
Imaging standardisation in metastatic colorectal cancer: A joint EORTC-ESOI-ESGAR expert consensus recommendation.
In: European Journal of Cancer, Bd. 176: S. 193-206
Fakih, Marwan G.; Kopetz, Scott; Kuboki, Yasutoshi; Kim, Tae Won; Munster, Pamela N.; Krauss, John C.; Falchook, Gerald S.; Han, Sae-Won; Heinemann, Volker; Muro, Kei; Strickler, John H.; Hong, David S.; Denlinger, Crystal S.; Girotto, Gustavo; Lee, Myung-Ah; Henary, Haby; Tran, Qui; Park, Joseph K.; Ngarmchamnanrith, Gataree; Prenen, Hans und Price, Timothy J.
(2022):
Sotorasib for previously treated colorectal cancers with KRAS(G12C) mutation (CodeBreaK100): a prespecified analysis of a single-arm, phase 2 trial.
In: Lancet Oncology, Bd. 23, Nr. 1: S. 115-124
Pichler, Theresia; Frank, Tamara; Maier, Sabrina; Batenhorst, Ineke; Albawi-Daltrozzo, Tanja; Harbeck, Nadia; Algul, Hana; Heinemann, Volker; Hermelink, Kerstin; Mumm, Friederike und Dinkel, Andreas
(2022):
Die Auswirkungen der COVID-19-Pandemie aus der Sicht ambulanter Krebspatienten.
In: Deutsche Medizinische Wochenschrift, Bd. 147, Nr. 10, E41-E49
Seufferlein, Thomas; Mayerle, Julia; Boeck, Stefan; Brunner, Thomas; Ettrich, Thomas J.; Grenacher, Lars; Gress, Thomas Mathias; Hackert, Thilo; Heinemann, Volker; Kestler, Angelika; Sinn, Marianne; Tannapfel, Andrea; Wedding, Ulrich und Uhl, Waldemar
(2022):
S3-Leitlinie zum exokrinen Pankreaskarzinom – Kurzversion 2.0 – Dezember 2021, AWMF-Registernummer: 032/010OL.
In: Zeitschrift für Gastroenterologie, Bd. 60, Nr. 6: S. 991-1037
Seufferlein, Thomas; Mayerle, Julia; Boeck, Stefan; Brunner, Thomas; Ettrich, Thomas J.; Grenacher, Lars; Gress, Thomas Mathias; Hackert, Thilo; Heinemann, Volker; Kestler, Angelika; Sinn, Marianne; Tannapfel, Andrea; Wedding, Ulrich und Uhl, Waldemar
(2022):
S3-Leitlinie zum exokrinen Pankreaskarzinom – Langversion 2.0 – Dezember 2021 – AWMF-Registernummer: 032/010OL.
In: Zeitschrift für Gastroenterologie, Bd. 60, Nr. 11, E812-E909
McCleary, Nadine J.; Harmsen, William S.; Haakenstad, Ellana; Cleary, James M.; Meyerhardt, Jeffrey A.; Zalcberg, John; Adams, Richard; Grothey, Axel; Sobrero, Alberto F.; Cutsem, Eric van; Goldberg, Richard M.; Peeters, Marc; Tabernero, Josep; Seymour, Matt; Saltz, Leonard B.; Giantonio, Bruce J.; Arnold, Dirk; Rothenberg, Mace L.; Koopman, Miriam; Schmoll, Hans-Joachim; Pitot, Henry C.; Hoff, Paulo M.; Tebbutt, Niall; Masi, Gianluca; Souglakos, John; Bokemeyer, Carsten; Heinemann, Volker; Yoshino, Takayuki; Chibaudel, Benoist; deGramont, Aimery; Shi, Qian und Lichtman, Stuart M.
(2022):
Metastatic Colorectal Cancer Outcomes by Age Among ARCAD First-and Second-Line Clinical Trials.
In: JNCI Cancer Spectrum, Bd. 6, Nr. 2, pkac014
Westphalen, C. Benedikt; Fine, Alexander D.; Andre, Fabrice; Ganesan, Shridar; Heinemann, Volker; Rouleau, Etienne; Turnbull, Clare; Palacios, Luis Garcia; Lopez, Jorge-Antonio; Sokol, Ethan S. und Mateo, Joaquin
(2022):
Pan-cancer Analysis of Homologous Recombination Repair-associated Gene Alterations and Genome-wide Loss-of-Heterozygosity Score.
In: Clinical Cancer Research, Bd. 28, Nr. 7: S. 1412-1421
Zhang, Danmei; Kruger, Stephan; Schirle, Karoline; Heinemann, Volker; Dorman, Klara; Westphalen, Benedikt; Weiss, Lena; Gebauer, Leonie; Gunther, Michael; Ormanns, Steffen; Werner, Jens; Bergwelt-Baildon, Michael von; Boeck, Stefan und Haas, Michael
(2022):
Clinical impact of structured post-operative surveillance in resected pancreatic adenocarcinoma: Results from a retrospective cohort study.
In: Oncology Research and Treatment, Bd. 46, Nr. 3: S. 106-115
Arends, Christopher Maximilian; Dimitriou, Savvina; Stahler, Arndt; Hablesreiter, Raphael; Strzelecka, Paulina M.; Stein, Catarina M.; Tilgner, Marlon; Saiki, Ryunosuke; Ogawa, Seishi; Bullinger, Lars; Modest, Dominik P.; Stintzing, Sebastian; Heinemann, Volker und Damm, Frederik
(2022):
Clonal hematopoiesis is associated with improved survival in patients with metastatic colorectal cancer from the FIRE-3 trial.
In: Blood, Bd. 139, Nr. 10: S. 1593-1597
Modest, Dominik Paul; Karthaus, Meinolf; Fruehauf, Stefan; Graeven, Ullrich; Müller, Lothar; König, Alexander Otto; Fischer von Weikersthal, Ludwig; Caca, Karel; Kretzschmar, Albrecht; Goekkurt, Eray; Haas, Siegfried; Kurreck, Annika; Stahler, Arndt; Held, Swantje; Jarosch, Armin; Horst, David; Reinacher-Schick, Anke; Kasper, Stefan; Heinemann, Volker; Stintzing, Sebastian und Trarbach, Tanja
(2022):
Panitumumab Plus Fluorouracil and Folinic Acid Versus Fluorouracil and Folinic Acid Alone as Maintenance Therapy in RAS Wild-Type Metastatic Colorectal Cancer: The Randomized PANAMA Trial (AIO KRK 0212).
In: Journal of Clinical Oncology, Bd. 40, Nr. 1: S. 72-82
Kurreck, Annika; Heinemann, Volker; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kaiser, Florian; Uhlig, Jens; Schenk, Michael; Freiberg-Richter, Jens; Peuser, Bettina; Denzlinger, Claudio; Graeven, Ullrich; Heinrich, Kathrin; Held, Swantje; Stahler, Arndt; Alig, Annabel Helga Sophie; Jelas, Ivan; Einem, Jobst C. von; Stintzing, Sebastian; Giessen-Jung, Clemens und Modest, Dominik P.
(2022):
Response and Disease Dynamics in Untreated Metastatic Colorectal Cancer With Bevacizumab-Based Sequential vs. Combination Chemotherapy-Analysis of the Phase 3 XELAVIRI Trial.
In: Frontiers in Oncology, Bd. 12, 751453
Fischer, Laura E.; Stintzing, Sebastian; Heinemann, Volker; Keilholz, Ulrich; Keune, Dietmar; Vollbrecht, Claudia; Burmeister, Thomas; Kind, Andreas; Weiss, Lena; Horst, David; Kirchner, Thomas; Klauschen, Frederick; Jung, Andreas; Westphalen, Christoph Benedikt und Jelas, Ivan
(2022):
Liquid Biopsy in Colorectal Cancer: Quo Vadis? Implementation of Liquid Biopsies in Routine Clinical Patient Care in Two German Comprehensive Cancer Centers.
In: Frontiers in Oncology, Bd. 12, 870411
Claass, Luise Victoria; Schultheiss, Christoph; Scholz, Rebekka; Paschold, Lisa; Simnica, Donjete; Heinemann, Volker; Stintzing, Sebastian und Binder, Mascha
(2022):
PD-L1 Amino Acid Position 88 Represents a Hotspot for PD-L1 Stability With Relevance for PD-L1 Inhibition.
In: Frontiers in Oncology, Bd. 12, 941666
Alig, Annabel H. S.; Heinemann, Volker; Geissler, Michael; Fischer von Weikersthal, Ludwig; Decker, Thomas; Heinrich, Kathrin; Held, Swantje; Weiss, Lena; Moosmann, Nicolas; Stahler, Arndt; Jelas, Ivan; Kurreck, Annika; Einem, Jobst C. von; Reinacher-Schick, Anke C.; Tannapfel, Andrea; Giessen-Jung, Clemens; Stintzing, Sebastian und Modest, Dominik P. von
(2022):
Exact Primary Tumor Location in mCRC: Prognostic Value and Predictive Impact on Anti-EGFR mAb Efficacy.
In: Cancers, Bd. 14, Nr. 3, 526
Randeu, Hannah; Bronkhorst, Abel J.; Mayer, Zsuzsanna; Oberhofer, Angela; Polatoglou, Eleni; Heinemann, Volker; Haas, Michael; Böck, Stefan und Holdenrieder, Stefan
(2022):
Preanalytical Variables in the Analysis of Mitochondrial DNA in Whole Blood and Plasma from Pancreatic Cancer Patients.
In: Diagnostics, Bd. 12, Nr. 8, 1905
Raschzok, Nathanael; Stintzing, Sebastian; Heinemann, Volker; Rauch, Geraldine; Ricke, Jens; Guckenberger, Matthias; Kurreck, Annika; Alig, Annabel H. S.; Stahler, Arndt; Bullinger, Lars; Schmelzle, Moritz; Schoening, Wenzel; Lurje, Georg; Krenzien, Felix; Haase, Oliver; Rau, Beate; Gebauer, Bernhard; Sauer, Igor M.; Pratschke, Johann und Modest, Dominik P.
(2022):
FIRE-9-PORT/AIO-KRK-0418: a prospective, randomized, open, multicenter Phase III trial to investigate the efficacy of adjuvant/additive chemotherapy in patients with definitely-treated metastatic colorectal cancer.
In: BMC Cancer, Bd. 22, Nr. 1, 359
Bilic, Patrick; Christ, Patrick; Li, Hongwei Bran; Vorontsov, Eugene; Ben-Cohen, Avi; Kaissis, Georgios; Szeskin, Adi; Jacobs, Colin; Mamani, Gabriel Efrain Humpire; Chartrand, Gabriel; Lohoefer, Fabian; Holch, Julian Walter; Sommer, Wieland; Hofmann, Felix; Hostettler, Alexandre; Lev-Cohain, Naama; Drozdzal, Michal; Amitai, Michal Marianne; Vivanti, Refael; Sosna, Jacob; Ezhov, Ivan; Sekuboyina, Anjany; Navarro, Fernando; Kofler, Florian; Paetzold, Johannes C.; Shit, Suprosanna; Hu, Xiaobin; Lipkova, Jana; Rempfler, Markus; Piraud, Marie; Kirschke, Jan; Wiestler, Benedikt; Zhang, Zhiheng; Huelsemeyer, Christian; Beetz, Marcel; Ettlinger, Florian; Antonelli, Michela; Bae, Woong; Bellver, Miriam; Bi, Lei; Chen, Hao; Chlebus, Grzegorz; Dam, Erik B.; Dou, Qi; Fu, Chi-Wing; Georgescu, Bogdan; Giro-I-Nieto, Xavier; Gruen, Felix; Han, Xu; Heng, Pheng-Ann; Hesser, Jürgen; Moltz, Jan Hendrik; Igel, Christian; Isensee, Fabian; Jaeger, Paul; Jia, Fucang; Kaluva, Krishna Chaitanya; Khened, Mahendra; Kim, Ildoo; Kim, Jae-Hun; Kim, Sungwoong; Kohl, Simon; Konopczynski, Tomasz; Kori, Avinash; Krishnamurthi, Ganapathy; Li, Fan; Li, Hongchao; Li, Junbo; Li, Xiaomeng; Lowengrub, John; Ma, Jun; Maier-Hein, Klaus; Maninis, Kevis-Kokitsi; Meine, Hans; Merhof, Dorit; Pai, Akshay; Perslev, Mathias; Petersen, Jens; Pont-Tuset, Jordi; Qi, Jin; Qi, Xiaojuan; Rippel, Oliver; Roth, Karsten; Sarasua, Ignacio; Schenk, Andrea; Shen, Zengming; Torres, Jordi; Wachinger, Christian; Wang, Chunliang; Weninger, Leon; Wu, Jianrong; Xu, Daguang; Yang, Xiaoping; Yu, Simon Chun-Ho; Yuan, Yading; Yue, Miao; Zhang, Liping; Cardoso, Jorge; Bakas, Spyridon; Braren, Rickmer; Heinemann, Volker; Pal, Christopher; Tang, An; Kadoury, Samuel; Soler, Luc; Ginneken, Bram van; Greenspan, Hayit; Joskowicz, Leo und Menze, Bjoern
(2022):
The Liver Tumor Segmentation Benchmark (LiTS).
In: Medical Image Analysis, Bd. 84, 102680
Sultova, Elena; Westphalen, C. Benedikt; Jung, Andreas; Kumbrink, Joerg; Kirchner, Thomas; Mayr, Doris; Rudelius, Martina; Ormanns, Steffen; Heinemann, Volker; Metzeler, Klaus H.; Greif, Philipp A.; Burges, Alexander; Trillsch, Fabian; Mahner, Sven; Harbeck, Nadia und Wuerstlein, Rachel
(2021):
NGS-guided precision oncology in metastatic breast and gynecological cancer: first experiences at the CCC Munich LMU.
In: Archives of gynecology and obstetrics, Bd. 303, Nr. 5: S. 1331-1345
[PDF, 1MB]
Vangala, Deepak; Ladigan, Swetlana; Liffers, Sven-Thorsten; Noseir, Soha; Maghnouj, Abdelouahid; Götze, Tina-Maria; Verdoodt, Berlinda; Klein-Scory, Susanne; Godfrey, Laura; Zowada, Martina K.; Huerta, Mario; Edelstein, Daniel L.; Villarreal, Jaime Martinez de; Marqués, Miriam; Kumbrink, Jörg; Jung, Andreas; Schiergens, Tobias S.; Werner, Jens; Heinemann, Volker; Stintzing, Sebastian; Lindoerfer, Doris ORCID: https://orcid.org/0000-0003-3078-0856; Mansmann, Ulrich; Pohl, Michael; Teschendorf, Christian; Bernhardt, Christiane; Wolters, Heiner; Stern, Josef; Usta, Selami; Viebahn, Richard; Admard, Jacob; Casadei, Nicolas; Fröhling, Stefan; Ball, Claudia R.; Siveke, Jens T.; Glimm, Hanno; Tannapfel, Andrea; Schmiegel, Wolff und Hahn, Stephan A.
(2021):
Secondary resistance to anti-EGFR therapy by transcriptional reprogramming in patient-derived colorectal cancer models.
In: Genome Medicine, Bd. 13, Nr. 116
[PDF, 4MB]
Arai, Hiroyuki; Cao, Shu; Battaglin, Francesca; Wang, Jingyuan; Kawanishi, Natsuko; Tokunaga, Ryuma; Loupakis, Fotios; Stintzing, Sebastian; Soni, Shivani; Zhang, Wu; Mancao, Christoph; Salhia, Bodour; Mumenthaler, Shannon M.; Cremolini, Chiara; Heinemann, Volker; Falcone, Alfredo; Millstein, Joshua und Lenz, Heinz-Josef
(2021):
RNA-Binding Protein Polymorphisms as Novel Biomarkers to Predict Outcomes of Metastatic Colorectal Cancer: A Meta-analysis from TRIBE, FIRE-3, and MAVERICC.
In: Molecular Cancer Therapeutics, Bd. 20, Nr. 6: S. 1153-1160
Arai, Hiroyuki; Millstein, Joshua; Loupakis, Fotios; Stintzing, Sebastian; Wang, Jingyuan; Battaglin, Francesca; Kawanishi, Natsuko; Jayachandran, Priya; Soni, Shivani; Zhang, Wu; Mumenthaler, Shannon M.; Cremolini, Chiara; Heinemann, Volker; Falcone, Alfredo und Lenz, Heinz-Josef
(2021):
Germ line polymorphisms of genes involved in pluripotency transcription factors predict efficacy of cetuximab in metastatic colorectal cancer.
In: European Journal of Cancer, Bd. 150: S. 133-142
Cohen, Romain; Liu, Heshan; Fiskum, Jack; Adams, Richard; Chibaudel, Benoist; Maughan, Timothy S.; Cutsem, Eric van; Venook, Alan; Douillard, Jean-Yves; Heinemann, Volker; Punt, Cornelis Ja; Falcone, Alfredo; Bokemeyer, Carsten; Kaplan, Richard; Lenz, Heinz-Josef; Koopman, Miriam; Yoshino, Takayuki; Zalcberg, John; Grothey, Alex; Gramont, Aimery de; Shi, Qian und Andre, Thierry
(2021):
BRAF(V600E) Mutation in First-Line Metastatic Colorectal Cancer: An Analysis of Individual Patient Data From the ARCAD Database.
In: Jnci-Journal of the National Cancer Institute, Bd. 113, Nr. 10, djab042: S. 1386-1395
Gebauer, Leonie; Moltz, Jan H.; Mühlberg, Alexander; Holch, Julian W.; Huber, Thomas; Enke, Johanna; Jäger, Nils; Haas, Michael; Kruger, Stephan; Boeck, Stefan; Sühling, Michael; Katzmann, Alexander; Hahn, Horst; Kunz, Wolfgang G.; Heinemann, Volker; Noerenberg, Dominik und Maurus, Stefan
(2021):
Quantitative Imaging Biomarkers of the Whole Liver Tumor Burden Improve Survival Prediction in Metastatic Pancreatic Cancer.
In: Cancers, Bd. 13, Nr. 22, 5732
Heinrich, Kathrin; Modest, Dominik P.; Ricard, Ingrid; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kaiser, Florian; Graeven, Ullrich; Uhlig, Jens; Schenk, Michael; Freiberg-Richter, Jens; Peuser, Bettina; Denzlinger, Claudio; Giessen-Jung, Clemens; Stahler, Arndt; Michl, Marlies; Held, Swantje; Jung, Andreas; Kirchner, Thomas; Stintzing, Sebastian und Heinemann, Volker
(2021):
Gender-dependent survival benefit from first-line irinotecan in metastatic colorectal cancer. Subgroup analysis of a phase III trial (XELAVIRI-study, AIO-KRK-0110).
In: European Journal of Cancer, Bd. 147: S. 128-139
Kunzmann, Volker; Siveke, Jens T.; Alguel, Hana; Goekkurt, Eray; Siegler, Gabriele; Martens, Uwe; Waldschmidt, Dirk; Pelzer, Uwe; Fuchs, Martin; Kullmann, Frank; Boeck, Stefan; Ettrich, Thomas J.; Held, Swantje; Keller, Ralph; Klein, Ingo; Germer, Christoph-Thomas; Stein, Hubert; Friess, Helmut; Bahra, Marcus; Jakobs, Ralf; Hartlapp, Ingo und Heinemann, Volker
(2021):
Nab-paclitaxel plus gemcitabine versus nab-paclitaxel plus gemcitabine followed by FOLFIRINOX induction chemotherapy in locally advanced pancreatic cancer (NEOLAP-AIO-PAK-0113): a multicentre, randomised, phase 2 trial.
In: Lancet Gastroenterology & Hepatology, Bd. 6, Nr. 2: S. 128-138
Liu, Lian; Erickson, Nicole Tonya; Ricard, Ingrid; Weikersthal, Ludwig Fischer von; Lerch, Markus M.; Decker, Thomas; Kiani, Alexander; Kaiser, Florian; Heintges, Tobias; Kahl, Christoph; Kullmann, Frank; Scheithauer, Werner; Link, Hartmut; Hoeffkes, Heinz-Gert; Moehler, Markus; Gesenhues, Alena Britta; Theurich, Sebastian; Michl, Marlies; Modest, Dominik P.; Alguel, Hana; Stintzing, Sebastian; Heinemann, Volker und Holch, Julian W.
(2021):
Early weight loss is an independent risk factor for shorter survival and increased side effects in patients with metastatic colorectal cancer undergoing first-line treatment within the randomized Phase III trial FIRE-3 (AIO KRK-0306).
In: International Journal of Cancer, Bd. 150, Nr. 1: S. 112-123
Moehler, Markus; Folprecht, Gunnar; Heinemann, Volker; Holch, Julian Walter; Maderer, Annett; Kasper, Stefan; Hegewisch-Becker, Susanna; Schroeder, Jan; Overkamp, Friedrich; Kullmann, Frank; Bechstein, Wolf Otto; Voehringer, Matthias; Oellinger, Robert; Lordick, Florian; Geissler, Michael; Schulz-Abelius, Armin; Linz, Bernhard; Bernhard, Helga; Paul, Andreas; Schmidtmann, Irene; Potthoff, Karin und Schimanski, Carl Christoph
(2021):
Survival after secondary liver resection in metastatic colorectal cancer: Comparing data of three prospective randomized European trials (LICC, CELIM, FIRE-3).
In: International Journal of Cancer, Bd. 150, Nr. 8: S. 1341-1349
Naseem, Madiha; Cao, Shu; Yang, Dongyun; Millstein, Joshua; Puccini, Alberto; Loupakis, Fotios; Stintzing, Sebastian; Cremolini, Chiara; Tokunaga, Ryuma; Battaglin, Francesca; Soni, Shivani; Berger, Martin D.; Barzi, Afsaneh; Zhang, Wu; Falcone, Alfredo; Heinemann, Volker und Lenz, Heinz-Josef
(2021):
Random survival forests identify pathways with polymorphisms predictive of survival in KRAS mutant and KRAS wild-type metastatic colorectal cancer patients.
In: Scientific Reports, Bd. 11, Nr. 1, 12191
Pichler, Theresia; Marten-Mittag, Birgitt; Hermelink, Kerstin; Telzerow, Eva; Frank, Tamara; Ackermann, Ulrike; Belka, Claus; Combs, Stephanie E.; Gratzke, Christian; Gschwend, Jürgen; Harbeck, Nadia; Heinemann, Volker; Herkommer, Kathleen; Kiechle, Marion; Mahner, Sven; Pigorsch, Steffi; Rauch, Josefine; Stief, Christian; Mumm, Friederike; Heussner, Pia; Herschbach, Peter und Dinkel, Andreas
(2021):
Distress in hospitalized cancer patients: Associations with personality traits, clinical and psychosocial characteristics.
In: Psycho-Oncology, Bd. 31, Nr. 5: S. 770-778
Rodler, Severin; Jung, Andreas; Greif, Philipp A.; Ruehlmann, Katharina; Apfelbeck, Maria; Tamalunas, Alexander; Kretschmer, Alexander; Schulz, Gerald B.; Szabados, Bernadett; Stief, Christian; Heinemann, Volker; Westphalen, Christoph B. und Casuscelli, Jozefina
(2021):
Routine application of next-generation sequencing testing in uro-oncology-Are we ready for the next step of personalised medicine?
In: European Journal of Cancer, Bd. 146: S. 1-10
Stahler, Arndt; Heinemann, Volker; Schuster, Veronika; Heinrich, Kathrin; Kurreck, Annika; Giessen-Jung, Clemens; Weikersthal, Ludwig Fischer von; Kaiser, Florian; Decker, Thomas; Held, Swantje; Graeven, Ullrich; Schwaner, Ingo; Denzlinger, Claudio; Schenk, Michael; Neumann, Jens; Kirchner, Thomas; Jung, Andreas; Kumbrink, Jorg; Stintzing, Sebastian und Modest, Dominik P.
(2021):
Consensus molecular subtypes in metastatic colorectal cancer treated with sequential versus combined fluoropyrimidine, bevacizumab and irinotecan (XELAVIRI trial).
In: European Journal of Cancer, Bd. 157: S. 71-80
Sultova, Elena; Westphalen, C. Benedikt; Jung, Andreas; Kumbrink, Jörg; Kirchner, Thomas; Mayr, Doris; Rudelius, Martina; Ormanns, Steffen; Heinemann, Volker; Metzeler, Klaus H.; Greif, Philipp A.; Hester, Anna; Mahner, Sven; Harbeck, Nadia und Würstlein, Rachel
(2021):
Implementation of Precision Oncology for Patients with Metastatic Breast Cancer in an Interdisciplinary MTB Setting.
In: Diagnostics, Bd. 11, Nr. 4, 733
Vangala, Deepak; Ladigan, Swetlana; Liffers, Sven T.; Noseir, Soha; Maghnouj, Abdelouahid; Gotze, Tina-Maria; Verdoodt, Berlinda; Klein-Scory, Susanne; Godfrey, Laura; Zowada, Martina K.; Huerta, Mario; Edelstein, Daniel L.; de Villarreal, Jaime Martinez; Marques, Miriam; Kumbrink, Jorg; Jung, Andreas; Schiergens, Tobias; Werner, Jens; Heinemann, Volker; Stintzing, Sebastian; Lindoerfer, Doris; Mansmann, Ulrich; Pohl, Michael; Teschendorf, Christian; Bernhardt, Christiane; Wolters, Heiner; Stern, Josef; Usta, Selami; Viebahn, Richard; Admard, Jacob; Casadei, Nicolas; Frohling, Stefan; Ball, Claudia R.; Siveke, Jens T.; Glimm, Hanno; Tannapfel, Andrea; Schmiegel, Wolff und Hahn, Stephan A.
(2021):
Secondary resistance to anti-EGFR therapy by transcriptional reprogramming in patient-derived colorectal cancer models.
In: Genome Medicine, Bd. 13, Nr. 1, 116
Wick, Antje; Baehr, Oliver; Schuler, Martin; Rohrberg, Kristoffer; Chawla, Sant P.; Janku, Filip; Schiff, David; Heinemann, Volker; Narita, Yoshitaka; Lenz, Heinz-Josef; Ikeda, Masafumi; Ando, Yuichi; Wick, Wolfgang; Steinbach, Joachim P.; Burger, Michael C.; Wenger, Katharina; Lassen, Ulrik; Sankhala, Kamalesh K.; Roggia, Cristiana; Genvresse, Isabelle; Munhoz, Catya; Rentzsch, Christine; Reschke, Susanne; Langer, Simon; Wagner, Markus; Kaulfuss, Stefan; Cai, Charles; Lagkadinou, Eleni; Jeffers, Michael; Pena, Carol und Tabatabai, Ghazaleh
(2021):
Phase I Assessment of Safety and Therapeutic Activity of BAY1436032 in Patients with IDH1-Mutant Solid Tumors.
In: Clinical Cancer Research, Bd. 27, Nr. 10: S. 2723-2733
Yin, Jun; Cohen, Romain; Jin, Zhaohui; Liu, Heshan; Pederson, Levi; Adams, Richard; Grothey, Axel; Maughan, Timothy S.; Venook, Alan; Cutsem, Eric van; Punt, Cornelis; Koopman, Miriam; Falcone, Alfredo; Tebbutt, Niall C.; Seymour, Matthew T.; Bokemeyer, Carsten; Rubio, Eduardo Diaz; Kaplan, Richard; Heinemann, Volker; Chibaudel, Benoist; Yoshino, Takayuki; Zalcberg, John; Andre, Thierry; Gramont, Aimery de; Shi, Qian und Lenz, Heinz-Josef
(2021):
Prognostic and Predictive Impact of Primary Tumor Sidedness for Previously Untreated Advanced Colorectal Cancer.
In: Jnci-Journal of the National Cancer Institute, Bd. 113, Nr. 12: S. 1705-1713
Yin, Jun; Dawood, Shaheenah; Cohen, Romain; Meyers, Jeff; Zalcberg, John; Yoshino, Takayuki; Seymour, Matthew; Maughan, Tim; Saltz, Leonard; Cutsem, Eric van; Venook, Alan; Schmoll, Hans-Joachim; Goldberg, Richard; Hoff, Paulo; Hecht, J. Randolph; Hurwitz, Herbert; Punt, Cornelis; Diaz Rubio, Eduard; Koopman, Miriam; Cremolini, Chiara; Heinemann, Volker; Tournigard, Christophe; Bokemeyer, Carsten; Fuchs, Charles; Tebbutt, Niall; Souglakos, John; Doulliard, Jean-Yves; Kabbinavar, Fairooz; Chibaudel, Benoist; Gramont, Aimery de; Shi, Qian; Grothey, Axel und Adams, Richard
(2021):
Impact of geography on prognostic outcomes of 21,509 patients with metastatic colorectal cancer enrolled in clinical trials: an ARCAD database analysis.
In: Therapeutic Advances in Medical Oncology, Bd. 13, 17588359211020547
Michl, Marlies; Taverna, F.; Kumbrink, Jörg; Schiergens, Tobias S.; Heinemann, Volker; Engel, Jutta; Kirchner, Thomas und Neumann, Jens
(9. Dezember 2020):
Biomarker alterations associated with distinct patterns of metastatic spread in colorectal cancer.
In: Virchows Archiv, Bd. 478: S. 695-705
[PDF, 1MB]
Thurmaier, Johannes; Heinemann, Volker; Engel, Jutta; Schubert‐Fritschle, Gabriele; Wiedemann, Max; Nüssler, Natascha C.; Ruppert, Reinhard; Kleeff, Jörg; Schepp, Wolfgang; Löhe, Florian; Karthaus, Meinolf; Neumann, Jens; Kumbrink, Jörg; Taverna, Francesco; Stahler, Arndt ORCID: https://orcid.org/0000-0003-1041-0137; Heinrich, Kathrin; Westphalen, Christoph Benedikt; Holch, Julian W.; Kirchner, Thomas und Michl, Marlies
(28. Oktober 2020):
Patients with colorectal cancer and brain metastasis: The relevance of extracranial metastatic patterns predicting time intervals to first occurrence of intracranial metastasis and survival.
In: International Journal of Cancer, Bd. 148, Nr. 8: S. 1919-1927
[PDF, 619kB]
Kruger, Stephan; Schirle, Karoline; Haas, Michael; Crispin, Alexander; Schirra, Jörg; Mayerle, Julia; D'Haese, Jan G.; Kunz, Wolfgang G.; Ricke, Jens; Ormanns, Steffen; Kirchner, Thomas; Kobold, Sebastian; Ilmer, Matthias; Gebauer, Leonie; Westphalen, Christoph B.; Bergwelt-Baildon, Michael von; Werner, Jens; Heinemann, Volker und Boeck, Stefan
(2020):
Prolonged time to treatment initiation in advanced pancreatic cancer patients has no major effect on treatment outcome: a retrospective cohort study controlled for lead time bias and waiting time paradox.
In: Journal of Cancer Research and Clinical Oncology, Bd. 146, Nr. 2: S. 391-399
Stahler, Arndt ORCID: https://orcid.org/0000-0003-1041-0137; Heinemann, Volker; Ricard, Ingrid; Einem, Jobst C. von; Giessen-Jung, Clemens; Westphalen, Christoph Benedikt; Michl, Marlies; Heinrich, Kathrin; Miller-Phillips, Lisa; Jelas, Ivan; Stintzing, Sebastian und Modest, Dominik Paul
(2020):
Current treatment options in RAS mutant metastatic colorectal cancer patients: a meta-analysis of 14 randomized phase III trials.
In: Journal of cancer research and clinical oncology, Bd. 146, Nr. 8: S. 2077-2087
[PDF, 1MB]
Ettrich, Thomas J.; Perkhofer, Lukas; Decker, Thomas; Hofheinz, Ralf-Dieter; Heinemann, Volker; Hoffmann, Thomas; Hebart, Holger F.; Herrmann, Thomas; Hannig, Carla V.; Buechner-Steudel, Petra; Guthle, Melanie; Hermann, Patrick C.; Berger, Andreas W. und Seufferlein, Thomas
(2020):
Nintedanib plusmFOLFOX6as second-line treatment of metastatic, chemorefractory colorectal cancer: The randomised, placebo-controlled, phaseII TRICC-Cstudy (AIO-KRK-0111).
In: International Journal of Cancer, Bd. 148, Nr. 6: S. 1428-1437
Muehlberg, Alexander; Holch, Julian W.; Heinemann, Volker; Huber, Thomas; Moltz, Jan; Maurus, Stefan; Jaeger, Nils; Liu, Lian; Froelich, Matthias F.; Katzmann, Alexander; Gresser, Eva; Taubmann, Oliver; Suehling, Michael und Noerenberg, Dominik
(2020):
The relevance of CT-based geometric and radiomics analysis of whole liver tumor burden to predict survival of patients with metastatic colorectal cancer.
In: European Radiology, Bd. 31, Nr. 2: S. 834-846
Pichler, Theresia; Rohrmoser, Amy; Letsch, Anne; Westphalen, C. Benedikt; Keilholz, Ulrich; Heinemann, Volker; Lamping, Mario; Jost, Philipp J.; Riedmann, Kristina; Herschbach, Peter und Goerling, Ute
(2020):
Information, communication, and cancer patients' trust in the physician: what challenges do we have to face in an era of precision cancer medicine?
In: Supportive Care in Cancer, Bd. 29, Nr. 4: S. 2171-2178
Froelich, Matthias F.; Petersen, Elina L.; Heinemann, Volker; Noerenberg, Dominik; Hesse, Nina; Gesenhues, Alena B.; Modest, Dominik P.; Sommer, Wieland H.; Hofmann, Felix O.; Stintzing, Sebastian und Holch, Julian W.
(2020):
Impact of Size and Location of Metastases on Early Tumor Shrinkage and Depth of Response in Patients With Metastatic Colorectal Cancer: Subgroup Findings of the Randomized, Open-Label Phase 3 Trial FIRE-3/AIO KRK-0306.
In: Clinical Colorectal Cancer, Bd. 19, Nr. 4: S. 291-300
Berger, Martin D.; Ning, Yan; Stintzing, Sebastian; Heinemann, Volker; Cao, Shu; Zhang, Wu; Yang, Dongyun; Miyamoto, Yuji; Suenaga, Mitsukuni; Schirripa, Marta; Hanna, Diana L.; Soni, Shivani; Puccini, Alberto; Tokunaga, Ryuma; Naseem, Madiha; Battaglin, Francesca; Cremolini, Chiara; Falcone, Alfredo; Loupakis, Fotios und Lenz, Heinz-Josef
(2020):
A polymorphism within the R-spondin 2 gene predicts outcome in metastatic colorectal cancer patients treated with FOLFIRI/bevacizumab: data from FIRE-3 and TRIBE trials.
In: European Journal of Cancer, Bd. 131: S. 89-97
Kurreck, Annika; Heinemann, Volker; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kaiser, Florian; Uhlig, Jens; Schenk, Michael; Freiberg-Richter, Jens; Peuser, Bettina; Denzlinger, Claudio; Graeven, Ullrich; Schwaner, Ingo; Stahler, Arndt; Heinrich, Kathrin; Jung, Andreas; Held, Swantje; von Einem, Jobst C.; Stintzing, Sebastian; Giessen-Jung, Clemens und Modest, Dominik P.
(2020):
Impact of age on efficacy and early mortality of initial sequential treatment versus upfront combination chemotherapy in patients with metastatic colorectal cancer: a subgroup analysis of a phase III trial (AIO KRK0110, XELAVIRI study).
In: European Journal of Cancer, Bd. 137: S. 81-92
Stahler, Arndt; Stintzing, Sebastian; Einem, Jobst C. von; Westphalen, Christoph B.; Heinrich, Kathrin; Kraemer, Nicole; Michl, Marlies; Modest, Dominik P.; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Heintges, Tobias; Kahl, Christoph; Kullmann, Frank; Scheithauer, Werner; Moehler, Markus; Kaiser, Florian; Kirchner, Thomas; Jung, Andreas und Heinemann, Volker
(2020):
Single-nucleotide variants, tumour mutational burden and microsatellite instability in patients with metastatic colorectal cancer: Next-generation sequencing results of the FIRE-3 trial.
In: European Journal of Cancer, Bd. 137: S. 250-259
Rodler, Severin; Apfelbeck, Maria; Schulz, Gerald Bastian; Ivanova, Troya; Buchner, Alexander; Staehler, Michael; Heinemann, Volker; Stief, Christian und Casuscelli, Jozefina
(2020):
Telehealth in Uro-oncology Beyond the Pandemic: Toll or Lifesaver?
In: European Urology Focus, Bd. 6, Nr. 5: S. 1097-1103
Guenther, Michael; Haas, Michael; Heinemann, Volker; Kruger, Stephan; Westphalen, Christoph Benedikt; Bergwelt-Baildon, Michael von; Mayerle, Julia; Werner, Jens; Kirchner, Thomas; Boeck, Stefan und Ormanns, Steffen
(2020):
Bacterial lipopolysaccharide as negative predictor of gemcitabine efficacy in advanced pancreatic cancer - translational results from the AIO-PK0104 Phase 3 study.
In: British Journal of Cancer, Bd. 123, Nr. 9: S. 1370-1376
Heinemann, Volker; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Kaiser, Florian; Al-Batran, Salah-Edin; Heintges, Tobias; Lerchenmüller, Christoph; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Moehler, Markus; Scheithauer, Werner; Held, Swantje; Miller-Phillips, Lisa; Modest, Dominik Paul; Jung, Andreas; Kirchner, Thomas und Stintzing, Sebastian
(2020):
FOLFIRI plus cetuximab or bevacizumab for advanced colorectal cancer: final survival and per-protocol analysis of FIRE-3, a randomised clinical trial.
In: British Journal of Cancer, Bd. 124, Nr. 3: S. 587-594
Mühlberg, Alexander; Katzmann, Alexander; Heinemann, Volker; Kärgel, Rainer; Wels, Michael; Taubmann, Oliver; Lades, Felix; Huber, Thomas; Maurus, Stefan; Holch, Julian; Faivre, Jean-Baptiste; Sühling, Michael; Nörenberg, Dominik und Remy-Jardin, Martine
(2020):
The Technome - A Predictive Internal Calibration Approach for Quantitative Imaging Biomarker Research.
In: Scientific Reports, Bd. 10, Nr. 1, 1103
[PDF, 3MB]
Westphalen, C. Benedikt; Heinemann, Volker; Tessen, Hans Werner; Groschek, Matthias; Hoeffkes, Heinz-Gert; Marschner, Norbert; Schulze, Mathias; Beringer, Andreas und Waldschmidt, Dirk
(2020):
Erlotinib plus Gemcitabin als Therapie bei Patienten mit metastasiertem Pankreaskarzinom: Ergebnisse einer nicht-interventionellen Studie.
In: Zeitschrift für Gastroenterologie, Bd. 58, Nr. 4: S. 332-340
Schimanski, Carl Christoph; Kasper, Stefan; Hegewisch-Becker, Susanna; Schroeder, Jan; Overkamp, Friedrich; Kullmann, Frank; Bechstein, Wolf Otto; Voehringer, Matthias; Oellinger, Robert; Lordick, Florian; Heinemann, Volker; Geissler, Michael; Schulz-Abelius, Armin; Bernhard, Helga; Schoen, Michael R.; Greil, Richard; Galle, Peter; Lang, Hauke; Schmidtmann, Irene und Moehler, Markus
(2020):
Adjuvant MUC vaccination with tecemotide after resection of colorectal liver metastases: a randomized, double-blind, placebo-controlled, multicenter AIO phase II trial (LICC).
In: Oncoimmunology, Bd. 9, Nr. 1, 1806680
Millstein, Joshua; Battaglin, Francesca; Barrett, Malcolm; Cao, Shu; Zhang, Wu; Stintzing, Sebastian; Heinemann, Volker und Lenz, Heinz-Josef
(2020):
Partition: a surjective mapping approach for dimensionality reduction.
In: Bioinformatics, Bd. 36, Nr. 3: S. 676-681
Mahajan, Ujjwal M.; Goni, Elisabetta; Langhoff, Enno; Li, Qi; Costello, Eithne; Greenhalf, William; Kruger, Stephan; Ormanns, Steffen; Halloran, Christopher; Ganeh, Paula; Marron, Manuela; Laemmerhirt, Felix; Zhao, Yue; Beyer, Georg; Weiss, Frank-Ulrich; Sendler, Matthias; Bruns, Christiane J.; Kohlmann, Thomas; Kirchner, Thomas; Werner, Jens; D'Haese, Jan G.; Bergwelt, Michael von; Heinemann, Volker; Neoptolemos, John P.; Buechler, Markus W.; Belka, Claus; Boeck, Stefan; Lerch, Markus M. und Mayerle, Julia
(2020):
Cathepsin D Expression and Gemcitabine Resistance in Pancreatic Cancer.
In: Jnci Cancer Spectrum, Bd. 4, Nr. 1, pkz060
Schulz, Christoph; Heinemann, Volker; Heinrich, Kathrin; Haas, Michael; Holch, Julian W.; Fraccaroli, Alessia; Held, Swantje; Einem, Jobst C.von; Modest, Dominik P.; Fischer von Weikersthal, Ludwig; Kullmann, Frank; Moehler, Markus; Scheithauer, Werner; Jung, Andreas und Stintzing, Sebastian
(2020):
Predictive and prognostic value of magnesium serum level in FOLFIRI plus cetuximab or bevacizumab treated patients with stage IV colorectal cancer: results from the FIRE-3 (AIO KRK-0306) study.
In: Anti-Cancer Drugs, Bd. 31, Nr. 8: S. 856-865
Stahler, Arndt; Stintzing, Sebastian; Modest, Dominik P.; Ricard, Ingrid; Giessen-Jung, Clemens; Kapaun, Christine; Ivanova, Boryana; Kaiser, Florian; Fischer von Weikersthal, Ludwig; Moosmann, Nicolas; Schalhorn, Andreas; Stauch, Martina; Kiani, Alexander; Held, Swantje; Decker, Thomas; Moehler, Markus; Neumann, Jens; Kirchner, Thomas; Jung, Andreas und Heinemann, Volker
(2020):
Amphiregulin Expression Is a Predictive Biomarker for EGFR Inhibition in Metastatic Colorectal Cancer: Combined Analysis of Three Randomized Trials.
In: Clinical Cancer Research, Bd. 26, Nr. 24: S. 6559-6567
Westphalen, C. Benedikt; Kukiolka, Tobias; Garlipp, Benjamin; Hahn, Lars; Fuchs, Martin; Malfertheiner, Peter; Reiser, Marcel; Kuetting, Fabian; Heinemann, Volker; Beringer, Andreas und Waldschmidt, Dirk T.
(2020):
Correlation of skin rash and overall survival in patients with pancreatic cancer treated with gemcitabine and erlotinib - results from a non-interventional multi-center study.
In: BMC Cancer, Bd. 20, Nr. 1
Cutsem, Eric van; Tempero, Margaret A.; Sigal, Darren; Oh, Do-Youn; Fazio, Nicola; Macarulla, Teresa; Hitre, Erika; Hammel, Pascal; Hendifar, Andrew E.; Bates, Susan E.; Li, Chung-Pin; Hingorani, Sunil R.; de la Fouchardiere, Christelle; Kasi, Anup; Heinemann, Volker; Maraveyas, Anthony; Bahary, Nathan; Layos, Laura; Sahai, Vaibhav; Zheng, Lei; Lacy, Jill; Park, Joon Oh; Portales, Fabienne; Oberstein, Paul; Wu, Wilson; Chondros, Dimitrios und Bullock, Andrea J.
(2020):
Randomized Phase III Trial of Pegvorhyaluronidase Alfa With Nab-Paclitaxel Plus Gemcitabine for Patients With Hyaluronan-High Metastatic Pancreatic Adenocarcinoma.
In: Journal of Clinical Oncology, Bd. 38, Nr. 27: S. 3185-3196
Modest, Dominik Paul; Heinemann, Volker; Folprecht, Gunnar; Denecke, Timm; Pratschke, Johann; Lang, Hauke; Bemelmans, Marc; Becker, Thomas; Rentsch, Markus; Seehofer, Daniel; Bruns, Christiane J.; Gebauer, Bernhard; Held, Swantje; Stahler, Arndt; Heinrich, Kathrin; Einem, Jobst C. von; Stintzing, Sebastian; Neumann, Ulf P. und Ricard, Ingrid
(2020):
Factors That Influence Conversion to Resectability and Survival After Resection of Metastases in RAS WT Metastatic Colorectal Cancer (mCRC): Analysis of FIRE-3-AIOKRK0306.
In: Annals of Surgical Oncology, Bd. 27, Nr. 7: S. 2389-2401
Nasseh, Daniel; Schneiderbauer, Sophie; Lange, Michael; Schweizer, Diana; Heinemann, Volker; Belka, Claus; Cadenovic, Ranko; Buysse, Laurence; Erickson, Nicole; Müller, Michael; Kortuem, Karsten; Niyazi, Maximilian; Marschner, Sebastian und Fey, Theres
(2020):
Optimizing the Analytical Value of Oncology-Related Data Based on an In-Memory Analysis Layer: Development and Assessment of the Munich Online Comprehensive Cancer Analysis Platform.
In: Journal of Medical Internet Research, Bd. 22, Nr. 4, e16533
Baumgarten, Louisa von; Kumbrink, Jörg; Jung, Andreas; Reischer, Anna; Flach, Madeleine; Liebmann, Sibylle; Metzeler, Klaus H.; Holch, Julian W.; Niyazi, Maximilian; Thon, Niklas; Straube, Andreas; Bergwelt-Baildon, Michael von; Heinemann, Volker; Kirchner, Thomas und Westphalen, Christoph Benedikt
(2020):
Therapeutic management of neuro-oncologic patients - potential relevance of CSF liquid biopsy.
In: Theranostics, Bd. 10, Nr. 2: S. 856-866
Westphalen, Benedikt C.; Bokemeyer, Carsten; Buettner, Reinhard; Froehling, Stefan; Gaidzik, Verena I.; Glimm, Hanno; Hacker, Ulrich T.; Heinemann, Volker; Illert, Anna L.; Keilholz, Ulrich; Kindler, Thomas; Kirschner, Martin; Schilling, Bastian; Siveke, Jens T.; Schroeder, Thomas; Tischler, Verena; Wagner, Sebastian; Weichert, Wilko; Zips, Daniel und Loges, Sonja
(2020):
Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group 'Molecular Diagnostics and Therapy'.
In: European Journal of Cancer, Bd. 135: S. 1-7
Attenberger, Ulrike; Rödel, Claus; Ghadimi, Michael; Piso, Pompilio; Arnold, Dirk; Folprecht, Gunnar; Geissler, Michael; Hegewisch-Becker, Susanna; Heinemann, Volker; Kasper, Stefan; Modest, Dominik; Reinacher-Schick, Anke; Seufferlein, Thomas; Stein, Alexander; Stintzin, Sebastian und Hofhein, Ralf-Dieter
(2020):
Stellenwert und qualitative Voraussetzungen der Magnetresonanztomografie für die Therapieplanung beim lokal fortgeschrittenen Rektumkarzinom – Interdisziplinäre Empfehlungen.
In: Zeitschrift für Gastroenterologie, Bd. 58, Nr. 6: S. 577-582
Modest, Dominik P.; Martens, Uwe M.; Riera-Knorrenschild, Jörge; Greeve, Jobst; Florschuetz, Axel; Wessendorf, Swen; Ettrich, Thomas; Kanzler, Stephan; Noerenberg, Dominik; Ricke, Jens; Seidensticker, Max; Held, Swantje; Buechner-Steudel, Petra; Atzpodien, Jens; Heinemann, Volker; Seufferlein, Thomas; Tannapfel, Andrea; Reinacher-Schick, Anke C. und Geissler, Michael
(2019):
FOLFOXIRI Plus Panitumumab As First-Line Treatment of RAS Wild-Type Metastatic Colorectal Cancer: The Randomized, Open-Label, Phase II VOLFI Study (AIO KRK0109).
In: Journal of Clinical Oncology, Bd. 37, Nr. 35
Rohrmoser, Amy; Pichler, Theresia; Letsch, Anne; Westphalen, C. Benedikt; Keilholz, Ulrich; Heinemann, Volker; Goerling, Ute und Herschbach, Peter
(2019):
Cancer patients' expectations when undergoing extensive molecular diagnostics-A qualitative study.
In: Psycho-Oncology, Bd. 29, Nr. 2: S. 423-429
Boesch, Florian; Todorova, Rumyana; Link, Helena; Westphalen, C. Benedikt; Böck, Stefan; Heinemann, Volker; Werner, Jens; Kirchner, Thomas; Angele, Martin K. und Neumann, Jens
(2019):
Molecular subtyping of gastric cancer with respect to the growth pattern of lymph-node metastases.
In: Journal of Cancer Research and Clinical Oncology, Bd. 145, Nr. 11: S. 2689-2697
Einem, Jobst Christian von; Guenther, Christine; Volk, Hans-Dieter; Gruetz, Gerald; Hirsch, Daniela; Salat, Christoph; Stoetzer, Oliver; Nelson, Peter J.; Michl, Marlies; Modest, Dominik P.; Holch, Julian W.; Angele, Martin; Bruns, Christiane; Niess, Hanno und Heinemann, Volker
(2019):
Treatment of advanced gastrointestinal cancer with genetically modified autologous mesenchymal stem cells: Results from the phase 1/2 TREAT-ME-1 trial.
In: International Journal of Cancer, Bd. 145, Nr. 6: S. 1538-1546
Burzykowski, Tomasz; Coart, Elisabeth; Saad, Everardo D.; Shi, Qian; Sommeijer, Dirkje W.; Bokemeyer, Carsten; Diaz-Rubio, Eduardo; Douillard, Jean-Yves; Falcone, Alfredo; Fuchs, Charles S.; Goldberg, Richard M.; Hecht, J. Randolph; Hoff, Paulo M.; Hurwitz, Herbert; Kabbinavar, Fairooz F.; Koopman, Miriam; Maughan, Timothy S.; Punt, Cornelis J. A.; Saltz, Leonard; Schmoll, Hans-Joachim; Seymour, Matthew T.; Tebbutt, Niall C.; Tournigand, Christophe; Van Cutsem, Eric; de Gramont, Aimery; Zalcberg, John R.; Buyse, Marc; Adam, Rene; Adams, Richard; Ajani, Jaffer; Allegra, Carmen Joseph; Andre, Thierry; Arnold, Dirk; Bachet, Jean-Baptiste; Benson, Al Bowen; Berlin, Jordan; Bleiberg, Harry; Bodoky, Gyorgy; Buyse, Marc; Chibaudel, Benoist; Diaz-Rubio, Eduardo; Douillard, Jean-Yves; Ellis, Lee; Eng, Cathy; Falcone, Alfredo; Franko, Jan; Fuchs, Charles S.; Fujii, Masashi; Giantonio, Bruce J.; Goldberg, Richard M.; de Gramont, Aimery; Grothey, Axel; Haller, Daniel; Hamilton, Stan R.; Hausner, Petr F.; Hecht, J. Randolph; Heinemann, Volker; Herrera, Alain; Hochster, Howard S.; Hoff, Paulo M.; Jonker, Derek J.; Kaplan, Rick; Koeberle, Dieter; Kopetz, Scott; Labianca, Roberto F.; Larsen, Annette K.; Lenz, Heinz-Joseph; Lieu, Christopher; Louvet, Christophe; Loupakis, Fotios; Marshall, John; Maughan, Timothy S.; Mayer, Robert J.; Meropol, Neal J.; Mitchell, Edith P.; O'Connell, Michael J.; Peeters, Marc; Porschen, Rainer; Price, Timothy; Punt, Cornelis J. A.; Salem, Mohamed E.; Saltz, Leonard; Schilsky, Richard; Schmoll, Hans-Joachim; Seymour, Matthew T.; Shmueli, Einat Shacham; Shi, Qian; Sobrero, Alberto; Souglakos, John; Tabernero, Josep; Taieb, Julien; Tebbutt, Niall C.; Tejpar, Sabine; Tempero, Margaret; Tournigand, Christophe; Tsuji, Yasushi; Van Cutsem, Eric; Venook, Alan P.; Yoshino, Takayuki; Weinberg, Benjamin A.; Wolmark, Norman und Zalcberg, John R.
(2019):
Evaluation of Continuous Tumor-Size-Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer.
In: Jama Network Open, Bd. 2, Nr. 9, e1911750
Riechelmann, Rachel P.; Srimuninnimit, Vichien; Bordonaro, Roberto; Kavan, Petr; Di Bartolomeo, Maria; Maiello, Evaristo; Cicin, Irfan; Garcia-Alfonso, Pilar; Chau, Ian; Fedyanin, Mikhail Y.; Fernandez Martos, Carlos; Ter-Ovanesov, Mikhail; Peeters, Marc; Ko, Yoo-Joung; Yalcin, Suayib; Karthaus, Meinolf; Aparicio, Jörge; Heinemann, Volker; Picard, Pascaline; Bury, Denise; Drea, Edward und Sobrero, Alberto
(2019):
Aflibercept Plus FOLFIRI for Second-line Treatment of Metastatic Colorectal Cancer: Observations from the Global Aflibercept Safety and Health-Related Quality-of-Life Program (ASQoP).
In: Clinical Colorectal Cancer, Bd. 18, Nr. 3
Krüger, Stephan; Ilmer, Matthias; Kobold, Sebastian; Cadilha, Bruno L.; Endres, Stefan; Ormanns, Steffen; Schuebbe, Gesa; Renz, Bernhard W.; D'Haese, Jan G.; Schloesser, Hans; Heinemann, Volker; Subklewe, Marion; Böck, Stefan; Werner, Jens und Bergwelt-Baildon, Michael von
(2019):
Advances in cancer immunotherapy 2019-latest trends.
In: Journal of Experimental & Clinical Cancer Research, Bd. 38, 268
Al-Batran, Salah-Eddin; Homann, Nils; Pauligk, Claudia; Götze, Thorsten O.; Meiler, Johannes; Kasper, Stefan; Kopp, Hans-Georg; Mayer, Frank; Haag, Georg Martin; Luley, Kim; Lindig, Udo; Schmiegel, Wolff; Pohl, Michael; Stoehlmacher, Jan; Folprecht, Gunnar; Probst, Stephan; Prasnikar, Nicole; Fischbach, Wolfgang; Mahlberg, Rolf; Trojan, Jörg; Königsmann, Michael; Martens, Uwe M.; Thuss-Patience, Peter; Egger, Matthias; Block, Andreas; Heinemann, Volker; Illerhaus, Gerald; Moehler, Markus; Schenk, Michael; Kullmann, Frank; Behringer, Dirk M.; Heike, Michael; Pink, Daniel; Teschendorf, Christian; Loehr, Carmen; Bernhard, Helga; Schuch, Gunter; Rethwisch, Volker; Fischer von Weikersthal, Ludwig; Hartmann, Jörg T.; Kneba, Michael; Daum, Severin; Schulmann, Karsten; Weniger, Jörg; Belle, Sebastian; Gaiser, Timo; Oduncu, Fuat S.; Guentner, Martina; Hozaeel, Wael; Reichart, Alexander; Jaeger, Elke; Kraus, Thomas; Moenig, Stefan; Bechstein, Wolf O.; Schuler, Martin; Schmalenberg, Harald und Hofheinz, Ralf D.
(2019):
Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial.
In: Lancet, Bd. 393, Nr. 10184: S. 1948-1957
Tokunaga, Ryuma; Cao, Shu; Naseem, Madiha; Lo, Jae Ho; Battaglin, Francesca; Puccini, Alberto; Berger, Martin D.; Soni, Shivani; Millstein, Joshua; Zhang, Wu; Stintzing, Sebastian; Loupakis, Fotios; Cremolini, Chiara; Heinemann, Volker; Falcone, Alfredo und Lenz, Heinz-Josef
(2019):
Prognostic Effect of Adenosine-related Genetic Variants in Metastatic Colorectal Cancer Treated With Bevacizumab-based Chemotherapy.
In: Clinical Colorectal Cancer, Bd. 18, Nr. 1, E8-E19
Bormann, Felix; Stinzing, Sebastian; Tierling, Sascha; Morkel, Markus; Markelova, Maria Rivera; Walter, Jorn; Weichert, Wilko; Rossner, Florian; Kuhn, Natalia; Perner, Juliane; Dietz, Johanna; Ispasanie, Sylvia; Dietel, Manfred; Schäfer, Reinhold; Heinemann, Volker und Sers, Christine
(2019):
Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer.
In: International Journal of Cancer, Bd. 144, Nr. 3: S. 569-581
Modest, Dominik Paul; Fischer von Weikersthal, Ludwig; Decker, Thomas; Vehling-Kaiser, Ursula; Uhlig, Jens; Schenk, Michael; Freiberg-Richter, Jens; Peuser, Bettina; Denzlinger, Claudio; Reddemann, Christina Peveling Genannt; Graeven, Ullrich; Schuch, Gunter; Schwaner, Ingo; Stahler, Arndt; Jung, Andreas; Kirchner, Thomas; Held, Swantje; Stintzing, Sebastian; Giessen-Jung, Clemens und Heinemann, Volker
(2019):
Sequential Versus Combination Therapy of Metastatic Colorectal Cancer Using Fluoropyrimidines, Irinotecan, and Bevacizumab: A Randomized, Controlled StudyXELAVIRI (AIO KRK0110).
In: Journal of Clinical Oncology, Bd. 37, Nr. 1
Laurent-Puig, Pierre; Grisoni, Marie-Lise; Heinemann, Volker; Liebaert, Francois; Neureiter, Daniel; Jung, Andreas; Montestruc, Francois; Gaston-Mathe, Yann; Thiebaut, Raphaeele und Stintzing, Sebastian
(2019):
Validation of miR-31-3p Expression to Predict Cetuximab Efficacy When Used as First-Line Treatment in RAS Wild-Type Metastatic Colorectal Cancer.
In: Clinical Cancer Research, Bd. 25, Nr. 1: S. 134-141
Suenaga, Mitsukuni; Stintzing, Sebastian; Cao, Shu; Zhang, Wu; Yang, Dongyun; Ning, Yan; Okazaki, Satoshi; Berger, Martin D.; Miyamoto, Yuji; Schirripa, Marta; Soni, Shivani; Barzi, Afsaneh; Heinemann, Volker und Lenz, Heinz-Josef
(2019):
Role of CCL5 and CCR5 gene polymorphisms in epidermal growth factor receptor signalling blockade in metastatic colorectal cancer: analysis of the FIRE-3 trial.
In: European Journal of Cancer, Bd. 107: S. 100-114
Pichler, Theresia; Dinkel, Andreas; Marten-Mittag, Birgitt; Hermelink, Kerstin; Telzerow, Eva; Ackermann, Ulrike; Belka, Claus; Combs, Stephanie E.; Gratzke, Christian; Gschwend, Jürgen; Harbeck, Nadia; Heinemann, Volker; Herkommer, Kathleen; Kiechle, Marion; Mahner, Sven; Pigorsch, Steffi; Rauch, Josefine; Stief, Christian; Beckmann, Jürgen; Heussner, Pia und Herschbach, Peter
(2019):
Factors associated with the decline of psychological support in hospitalized patients with cancer.
In: Psycho-Oncology, Bd. 28, Nr. 10: S. 2049-2059
Puccini, Alberto; Loupakis, Fotios; Stintzing, Sebastian; Cao, Shu; Battaglin, Francesca; Togunaka, Ryuma; Naseem, Madiha; Berger, Martin D.; Soni, Shivani; Zhang, Wu; Mancao, Christoph; Salhia, Bodour; Mumenthaler, Shannon M.; Weisenberger, Daniel J.; Liang, Gangning; Cremolini, Chiara; Heinemann, Volker; Falcone, Alfredo; Millstein, Joshua und Lenz, Heinz-Josef
(2019):
Impact of polymorphisms within genes involved in regulating DNA methylation in patients with metastatic colorectal cancer enrolled in three independent, randomised, open-label clinical trials: a meta-analysis from TRIBE, MAVERICC and FIRE-3.
In: European Journal of Cancer, Bd. 111: S. 138-147
Bösch, Florian; Brüwer, Katharina; Altendorf-Hofmann, Annelore; Auernhammer, Christoph J.; Spitzweg, Christine; Westphalen, Benedikt; Boeck, Stefan; Schubert-Fritschle, Gabriele; Werner, Jens; Heinemann, Volker; Kirchner, Thomas; Angele, Martin K. und Knösel, Thomas
(2019):
Immune checkpoint markers in gastroenteropancreatic neuroendocrine neoplasia.
In: Endocrine-Related Cancer, Bd. 26, Nr. 3: S. 293-301
Holch, Julian W.; Ricard, Ingrid; Stintzing, Sebastian; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al-Batran, Salah; Heintges, Tobias; Lerchenmüller, Christian; Kahl, Christoph; Kullmann, Frank; Scheithauer, Werner; Scholz, Michael; Müller, Sebastian; Link, Hartmut; Rost, Andreas; Höffkes, Heinz-Gert; Moehler, Markus; Lindig, Reinhard Udo; Miller-Phillips, Lisa; Kirchner, Thomas; Jung, Andreas; Einem, Jobst C. von; Modest, Dominik Paul und Heinemann, Volker
(2018):
Relevance of liver-limited disease in metastatic colorectal cancer: Subgroup findings of the FIRE-3/AIO KRK0306 trial.
In: International Journal of Cancer, Bd. 142, Nr. 5: S. 1047-1055
Modest, Dominik P.; Denecke, Timm; Pratschke, J.; Ricard, Ingrid; Lang, H.; Bemelmans, M.; Becker, T.; Rentsch, Markus; Seehofer, Daniel; Bruns, Christiane J.; Gebauer, B.; Modest, H. I.; Held, S.; Folprecht, Gunnar; Heinemann, Volker und Neumann, Ulf Peter
(2018):
Surgical treatment options following chemotherapy plus cetuximab or bevacizumab in metastatic colorectal cancer-central evaluation of FIRE-3.
In: European Journal of Cancer (EJC), Bd. 88: S. 77-86
Bokemeyer, Carsten; Busse, Reinhard; Engel, Jutta; Gebauer, Alexander; Hallek, Michael; Heinemann, Volker; Lüftner, Diana und Wörmann, Bernhard
(2018):
Der ältere Krebspatient - Herausforderungen im Krankenhaus und in der Praxis.
In: Oncology Research and Treatment, Bd. 41, Nr. Suppl 3: S. 2-26
[PDF, 569kB]
Froelich, Matthias F.; Stintzing, Sebastian; Kumbrink, Jörg; Grünewald, Thomas G. P.; Mansmann, Ulrich; Heinemann, Volker; Kirchner, Thomas und Jung, Andreas
(2018):
The DNA-polymorphism rs849142 is associated with skin toxicity induced by targeted anti-EGFR therapy using cetuximab.
In: OncoTarget, Bd. 9, Nr. 54: S. 30279-30288
[PDF, 3MB]
Hofmann, Felix O.; Holch, Julian W.; Heinemann, Volker; Ricard, Ingrid; Reiser, Maximilian F.; Baumann, Alena B.; Hesse, Nina; D'Anastasi, Melvin; Modest, Dominik P.; Stintzing, Sebastian und Sommer, Wieland H.
(2018):
Prognostic value of radiologically enlarged lymph nodes in patients with metastatic colorectal cancer: Subgroup findings of the randomized, open-label FIRE-3/AIO KRK0306 trial.
In: European Journal of Radiology, Bd. 100: S. 124-129
Salem, Mohamed E.; Yin, Jun; Weinberg, Benjamin A.; Renfro, Lindsay A.; Pederson, Levi D.; Maughan, Timothy S.; Adams, Richard A.; Cutsem, Eric van; Falcone, Alfredo; Tebbutt, Niall C.; Seymour, Matthew T.; Diaz-Rubio, Eduardo; Aranda, Enrique; Bokemeyer, Carsten; Heinemann, Volker; Wasan, Harpreet; Gramont, Aimery de; Grothey, Axel; Shi, Qian; Sargent, Daniel J. und Marshall, John L.
(2018):
Clinicopathological differences and survival outcomes with first-line therapy in patients with left-sided colon cancer and rectal cancer: Pooled analysis of 2879 patients from AGITG (MAX), COIN, FOCUS2, OPUS, CRYSTAL and COIN-B trials in the ARCAD database.
In: European Journal of Cancer, Bd. 103: S. 205-213
Suenaga, Mitsukuni; Schirripa, Marta; Cao, Shu; Zhang, Wu; Yang, Dongyun; Cremolini, Chiara; Lonardi, Sara; Bergamo, Francesca; Ning, Yang; Yamamoto, Noriko; Okazaki, Satoshi; Berger, Martin D.; Miyamoto, Yuji; Gopez, Roel; Barzi, Afsaneh; Yamaguchi, Toshiharu; Stintzing, Sebastian; Heinemann, Volker; Loupakis, Fotios; Falcone, Alfredo und Lenz, Heinz-Josef
(2018):
Potential role of PIN1 genotypes in predicting benefit from oxaliplatin-based and irinotecan-based treatment in patients with metastatic colorectal cancer.
In: Pharmacogenomics Journal, Bd. 18, Nr. 5: S. 623-632
Schulz, Christoph; Zhang, Wu; Lenz, Heinz-Josef; Neumann, Jens; Kullmann, Frank; Kunzmann, Volker; Fuchs, Martin; Heinemann, Volker; Holch, Julian Walter und Stintzing, Sebastian
(2018):
Germline polymorphisms (SNPs) to predict toxicity and efficacy in FLOT-treated patients with locally advanced gastroesophageal junction or gastric adenocarcinoma-data from the NeoFLOT study.
In: Translational Cancer Research, Bd. 7, Nr. 6: S. 1393-1405
Günther, Michael; Veninga, Vivien; Kumbrink, Jörg; Haas, Michael; Westphalen, C. Benedikt; Kruger, Stephan; Heinemann, Volker; Kirchner, Thomas; Böck, Stefan; Jung, Andreas und Ormanns, Steffen
(2018):
POLE gene hotspot mutations in advanced pancreatic cancer.
In: Journal of Cancer Research and Clinical Oncology, Bd. 144, Nr. 11: S. 2161-2166
Winter, Katharina S.; Hofmann, Felix O.; Thierfelder, Kolja M.; Holch, Julian W.; Hesse, Nina; Baumann, Alena B.; Modest, Dominik P.; Stintzing, Sebastian; Heinemann, Volker; Ricke, Jens; Sommer, Wieland H. und D'Anastasi, Melvin
(2018):
Towards volumetric thresholds in RECIST 1.1: Therapeutic response assessment in hepatic metastases.
In: European Radiology, Bd. 28, Nr. 11: S. 4839-4848
Berger, Martin D.; Stintzing, Sebastian; Heinemann, Volker; Cao, Shu; Yang, Dongyun; Sunakawa, Yu; Matsusaka, Satoshi; Ning, Yan; Okazaki, Satoshi; Miyamoto, Yuji; Suenaga, Mitsukuni; Schirripa, Marta; Hanna, Diana L.; Soni, Shivani; Puccini, Alberto; Zhang, Wu; Cremolini, Chiara; Falcone, Alfredo; Loupakis, Fotios und Lenz, Heinz-Josef
(2018):
A Polymorphism within the Vitamin D Transporter Gene Predicts Outcome in Metastatic Colorectal Cancer Patients Treated with FOLFIRI/Bevacizumab or FOLFIRI/Cetuximab.
In: Clinical Cancer Research, Bd. 24, Nr. 4: S. 784-793
Froelich, Matthias F.; Heinemann, Volker; Sommer, Wieland H.; Holch, Julian W.; Schöppe, Franziska; Hesse, Nina; Baumann, Alena B.; Kunz, Wolfgang G.; Reiser, Maximilian F.; Ricke, Jens; D'Anastasi, Melvin; Stintzing, Sebastian; Modest, Dominik P.; Kazmierczak, Philipp M. und Hofmann, Felix O.
(2018):
CT attenuation of liver metastases before targeted therapy is a prognostic factor of overall survival in colorectal cancer patients. Results from the randomised, open-label FIRE-3/AIO KRK0306 trial.
In: European Radiology, Bd. 28, Nr. 12: S. 5284-5292
McSkane, Michelle; Stintzing, Sebastian; Heinemann, Volker; Puccini, Alberto; Naseem, Madiha; Cao, Shu; Lenz, Heinz-Josef und Jelas, Ivan
(2018):
Association Between Height and Clinical Outcome in Metastatic Colorectal Cancer Patients Enrolled Onto a Randomized Phase 3 Clinical Trial: Data From the FIRE-3 Study.
In: Clinical Colorectal Cancer, Bd. 17, Nr. 3: S. 215-222
Gibbs, Peter; Heinemann, Volker; Sharma, Navesh K.; Taieb, Julien; Ricke, Jens; Peeters, Marc; Findlay, Michael; Robinson, Bridget; Jackson, Christopher; Strickland, Andrew; Gebski, Val; Buskirk, Mark van; Zhao, Huaqing und Hazel, Guy van
(2018):
Effect of Primary Tumor Side on Survival Outcomes in Untreated Patients With Metastatic Colorectal Cancer When Selective Internal Radiation Therapy Is Added to Chemotherapy: Combined Analysis of Two Randomized Controlled Studies.
In: Clinical Colorectal Cancer, Bd. 17, Nr. 4, E617-E629
Sjoquist, Katrin M.; Renfro, Lindsay A.; Simes, R. John; Tebbutt, Niall C.; Clarke, Stephen; Seymour, Matthew T.; Adams, Richard; Maughan, Timothy S.; Saltz, Leonard; Goldberg, Richard M.; Schmoll, Hans-Joachim; Cutsem, Eric van; Douillard, Jean-Yves; Hoff, Paulo M.; Hecht, Joel Randolph; Tournigand, Christophe; Punt, Cornelis J. A.; Koopman, Miriam; Hurwitz, Herbert; Heinemann, Volker und Zalcberg, John R.
(2018):
Personalizing Survival Predictions in Advanced Colorectal Cancer: The ARCAD Nomogram Project.
In: Jnci-Journal of the National Cancer Institute, Bd. 110, Nr. 6, djx253: S. 638-648
Schirripa, Marta; Zhang, Wu; Yang, Dongyun; Cao, Shu; Okazaki, Satoshi; Loupakis, Fotios; Berger, Martin D.; Ning, Yan; Miyamoto, Yuji; Suenaga, Mitsukuni; Alberti, Giulia; West, Jordan D.; Lonardi, Sara; Khoukaz, Taline; Bergamo, Francesca; Battaglin, Francesca; Antoniotti, Carlotta; Falcone, Alfredo; Stintzing, Sebastian; Heinemann, Volker und Lenz, Heinz-Josef
(2018):
NOS2 polymorphisms in prediction of benefit from first-line chemotherapy in metastatic colorectal cancer patients.
In: PLOS One
13(3), e0193640
[PDF, 2MB]
Herbst, Andreas; Vdovin, Nikolay; Gacesa, Sanja; Philipp, Alexander; Nagel, Dorothea; Holdt, Lesca M.; Winkel, Mark op den; Heinemann, Volker; Stieber, Petra; Graeven, Ullrich; Reinacher-Schick, Anke; Arnold, Dirk; Ricard, Ingrid; Mansmann, Ulrich; Hegewisch-Becker, Susanna und Kolligs, Frank T.
(2017):
Methylated free-circulating HPP1 DNA is an early response marker in patients with metastatic colorectal cancer.
In: International Journal of Cancer, Bd. 140, Nr. 9: S. 2134-2144
Stahler, Arndt; Heinemann, Volker; Neumann, Jens; Crispin, Alexander; Schalhorn, Andreas; Stintzing, Sebastian; Giessen-Jung, Clemens; Fischer von Weikersthal, Ludwig; Vehling-Kaiser, Ursula; Stauch, Martina; Quietzsch, Detlef; Holch, Julian W.; Kruger, Stephan; Haas, Michael; Michl, Marlies; Einem, Jobst von; Kirchner, Thomas; Jung, Andreas und Modest, Dominik P.
(2017):
Prevalence and influence on outcome of HER2/neu, HER3 and NRG1 expression in patients with metastatic colorectal cancer.
In: Anti-cancer drugs, Bd. 28, Nr. 7: S. 717-722
[PDF, 422kB]
Modest, Dominik P.; Ricard, Ingrid; Stintzing, Sebastian; Fischer von Weikersthal, L.; Decker, T.; Kiani, A.; Vehling-Kaiser, U.; Al-Batran, S.-E.; Heintges, T.; Kahl, C.; Seipelt, G.; Kullmann, F.; Scheithauer, W.; Moehler, M.; Westphalen, C. B.; Holch, Julian W.; Einem, J. C. von; Held, S. und Heinemann, Volker
(2017):
Evaluation of survival across several treatment lines in
metastatic colorectal cancer: analysis of the FIRE-3 trial (AIO KRK0306).
In: European Journal of Cancer, Bd. 84: S. 262-269
Modest, Dominik P.; Denecke, Timm; Pratschke, J.; Ricard, Ingrid; Lang, H.; Bemelmans, M.; Becker, T.; Rentsch, M.; Seehofer, D.; Bruns, C. J.; Gebauer, B.; Modest, H. I.; Held, S.; Folprecht, Gunnar; Heinemann, Volker und Neumann, Ulf Peter
(2017):
Surgical treatment options following chemotherapy plus cetuximab or bevacizumab in metastatic colorectal cancer-central evaluation of FIRE-3.
In: European Journal of Cancer, Bd. 88: S. 77-86
Paprottka, Karolin J.; Todica, Andrei; Ilhan, Harun; Rübenthaler, Johannes; Schoeppe, Franziska; Michl, Marlies; Heinemann, Volker; Bartenstein, Peter; Reiser, Maximilian F. und Paprottka, Philipp M.
(2017):
Evaluation of Visualization Using a 50/50 (Contrast Media/Glucose 5% Solution) Technique for Radioembolization as an Alternative to a Standard Sandwich Technique.
In: Cardiovascular and interventional Radiology, Bd. 40, Nr. 11: S. 1740-1747
Kruger, Stephan; Haas, Michael; Burkl, Carolin; Goehring, Peter; Kleespies, Axel; Röder, Falk; Gallmeier, Eike; Ormanns, Steffen; Westphalen, Christoph Benedikt; Heinemann, Volker; Rank, Andreas und Boeck, Stefan
(2017):
Incidence, outcome and risk stratification tools for venous thromboembolism in advanced pancreatic cancer - A retrospective cohort study.
In: Thrombosis Research, Bd. 157: S. 9-15
Holch, Julian Walter; Metzeler, Klaus Hans; Jung, Andreas; Riedmann, Kristina; Jost, Philipp Jakob; Weichert, Wilko; Kirchner, Thomas; Heinemann, Volker und Westphalen, Christoph Benedikt
(2017):
Universal Genomic Testing: The next step in oncological decision-making or a dead end street?
In: European Journal of Cancer, Bd. 82: S. 72-79
Bächmann, Sibylle; Ormanns, Steffen; Haas, Michael; Krüger, Stephan; Remold, Anna; Modest, Dominik Paul; Kirchner, Thomas; Jung, Andreas; Werner, Jens; Heinemann, Volker und Böck, Stefan
(2017):
Switch in KRAS mutational status during an unusual course of disease in a patient with advanced pancreatic adenocarcinoma: implications for translational research.
In: BMC Cancer
17:374
[PDF, 614kB]
Haas, Michael; Ormanns, Steffen; Bächmann, Sibylle; Remold, Anna; Krüger, Stephan; Westphalen, Christoph B.; Siveke, Jens T.; Wenzel, Patrick; Schlitter, Anna Melissa; Esposito, Irene; Quietzsch, Detlef; Clemens, Michael R.; Kettner, Erika; Laubender, Rüdiger P.; Jung, Andreas; Kirchner, Thomas; Böck, Stefan und Heinemann, Volker
(2017):
Extended RAS analysis and correlation with overall survival in advanced pancreatic cancer.
In: British Journal of Cancer, Bd. 116, Nr. 11: S. 1462-1469
Ormanns, Steffen; Haas, Michael; Remold, Anna; Kruger, Stephan; Holdenrieder, Stefan; Kirchner, Thomas; Heinemann, Volker und Boeck, Stefan
(2017):
The Impact of SMAD4 Loss on Outcome in Patients with Advanced Pancreatic Cancer Treated with Systemic Chemotherapy.
In: International Journal of Molecular Sciences, Bd. 18, Nr. 5, 1094
[PDF, 1MB]
Berger, Martin D.; Yamauchi, Shinichi; Cao, Shu; Hanna, Diana L.; Sunakawa, Yu; Schirripa, Marta; Matsusaka, Satoshi; Yang, Dongyun; Groshen, Susan; Zhang, Wu; Ning, Yan; Okazaki, Satoshi; Miyamoto, Yuji; Suenaga, Mitsukuni; Lonardi, Sara; Cremolini, Chiara; Falcone, Alfredo; Heinemann, Volker; Loupakis, Fotios; Stintzing, Sebastian und Lenz, Heinz-Josef
(2017):
Autophagy-related polymorphisms predict hypertension in patients with metastatic colorectal cancer treated with FOLFIRI and bevacizumab: Results from TRIBE and FIRE-3 trials.
In: European Journal of Cancer, Bd. 77: S. 13-20
Kruger, Stephan; Legenstein, Marie-Louise; Rösgen, Verena; Haas, Michael; Modest, Dominik Paul; Westphalen, Christoph Benedikt; Ormanns, Steffen; Kirchner, Thomas; Heinemann, Volker; Holdenrieder, Stefan und Boeck, Stefan
(2017):
Serum levels of soluble programmed death protein 1 (sPD-1) and soluble programmed death ligand 1 (sPD-L1) in advanced pancreatic cancer.
In: Oncoimmunology, Bd. 6, Nr. 5, e1310358
Einem, Jobst C. von; Peter, Sylvia; Günther, Christine; Volk, Hans-Dieter; Gürtz, Gerald; Salat, Christoph; Stötzer, Oliver; Nelson, Peter J.; Michl, Marlies; Modest, Dominik P.; Holch, Julian W.; Angele, Martin; Bruns, Christiane; Niess, Hanno und Heinemann, Volker
(2017):
Treatment of advanced gastrointestinal cancer with genetically modified autologous mesenchymal stem cells - TREAT-ME-1-a phase I, first in human, first in class trial.
In: Oncotarget, Bd. 8, Nr. 46: S. 80156-80166
Modest, Dominik P.; Stintzing, Sebastian; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al-Batran, Salah-Eddin; Heintges, Tobias; Lerchenmüller, Christian; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Scheithauer, Werner; Kirchner, Thomas; Jung, Andreas; Stauch, Martina; Einem, Jobst Christian von; Möhler, Markus; Held, Swantje und Heinemann, Volker
(2017):
Relation of early tumor shrinkage (ETS) observed in first-line treatment to efficacy parameters of subsequent treatment in FIRE-3 (AIOKRK0306).
In: International Journal of Cancer, Bd. 140, Nr. 8: S. 1918-1925
Holch, Julian Walter; Demmer, Maximilian; Lamersdorf, Charlotte; Michl, Marlies; Schulz, Christoph; Einem, Jobst Christian von; Modest, Dominik Paul und Heinemann, Volker
(2017):
Pattern and Dynamics of Distant Metastases in Metastatic Colorectal Cancer.
In: Visceral Medicine, Bd. 33, Nr. 1: S. 70-75
Cohn, Allen Lee; Yoshino, Takayuki; Heinemann, Volker; Obermannova, Radka; Bodoky, Gyorgy; Prausova, Jana; Garcia-Carbonero, Rocio; Ciuleanu, Tudor; Garcia-Alfonso, Pilar; Portnoy, David C.; Cutsem, Eric van; Yamazaki, Kentaro; Clingan, Philip R.; Polikoff, Jonathon; Lonardi, Sara; O'Brien, Lisa M.; Gao, Ling; Yang, Ling; Ferry, David; Nasroulah, Federico und Tabernero, Josep
(2017):
Exposure-response relationship of ramucirumab in patients with advanced second-line colorectal cancer: exploratory analysis of the RAISE trial.
In: Cancer Chemotherapy and Pharmacology, Bd. 80, Nr. 3: S. 599-608
[PDF, 1MB]
Strobl, Frederik Franz; Schwarz, Jens Benjamin; Häussler, Sophia Marie; Paprottka, Philipp Marius; Rist, Carsten; Thierfelder, Kolja Martin; Böck, Stefan; Heinemann, Volker; Reiser, Maximilian Ferdinand und Trumm, Christoph Gregor
(2017):
Percutaneous CT fluoroscopy-guided core biopsy of pancreatic lesions: technical and clinical outcome of 104 procedures during a 10-year period.
In: Acta Radiologica, Bd. 58, Nr. 8: S. 906-913
[PDF, 341kB]
Okazaki, Satoshi; Stintzing, Sebastian; Sunakawa, Yu; Cao, Shu; Zhang, Wu; Yang, Dongyun; Ning, Yan; Matsusaka, Satoshi; Berger, Martin D.; Miyamoto, Yuji; Suenaga, Mitsukuni; Schirripa, Marta; West, Jordan D.; Gopez, Roel; Akihito, Tsuji; Ichikawa, Wataru; Heinemann, Volker; DePaolo, R. William und Lenz, Heinz-Josef
(2017):
Predictive value of TLR7 polymorphism for cetuximab-based chemotherapy in patients with metastatic colorectal cancer.
In: International Journal of Cancer, Bd. 141, Nr. 6: S. 1222-1230
Schmiegel, Wolff; Buchberger, Barbara; Follmann, Markus; Graeven, Ullrich; Heinemann, Volker; Langer, Thomas; Nothacker, Monika; Porschen, Rainer; Rödel, Claus; Rösch, Thomas; Schmitt, Wolfgang; Wesselmann, Simone und Pox, Christian
(2017):
S3-Leitlinie – Kolorektales Karzinom.
In: Zeitschrift für Gastroenterologie, Bd. 55, Nr. 12: S. 1344-1498
Wasan, Harpreet S.; Gibbs, Peter; Sharma, Navesh K.; Taieb, Julien; Heinemann, Volker; Ricke, Jens; Peeters, Marc; Findlay, Michael; Weaver, Andrew; Mills, Jamie; Wilson, Charles; Adams, Richard; Francis, Anne; Moschandreas, Joanna; Virdee, Pradeep S.; Dutton, Peter; Love, Sharon; Gebski, Val; Gray, Alastair; Hazel, Guy van und Sharma, Ricky A.
(2017):
First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials.
In: Lancet Oncology, Bd. 18, Nr. 9: S. 1159-1171
Schirripa, Marta; Zhang, Wu; Heinemann, Volker; Cao, Shu; Okazaki, Satoshi; Yang, Dongyun; Loupakis, Fotios; Berger, Martin D.; Ning, Yan; Miyamoto, Yuji; Suenaga, Mitsukuni; Gopez, Roel F.; West, Jordan D.; Hanna, Diana; Barzi, Afsaneh; Falcone, Alfredo; Stintzing, Sebastian und Lenz, Heinz-Josef
(2017):
Single nucleotide polymorphisms in the IGF-IRS pathway are associated with outcome in mCRC patients enrolled in the FIRE-3 trial.
In: International Journal of Cancer, Bd. 141, Nr. 2: S. 383-392
Schiergens, Tobias S.; Renz, Bernhard W.; Reu, Simone; Neumann, Jens; Al-Sayegh, Rami; Niess, Hanno; Ilmer, Matthias; Kruger, Stephan; Böck, Stefan; Heinemann, Volker; Werner, Jens und Kleespies, Axel
(2017):
Prognostic Value of Preoperative Serum Carcinoembryonic Antigen and Carbohydrate Antigen 19-9 After Resection of Ampullary Cancer.
In: Journal of Gastrointestinal Surgery, Bd. 21, Nr. 11: S. 1775-1783
Wasan, Harpreet; Hazel, Guy van; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321; Sharma, Navesh; Taieb, Julien; Ricke, Jens; Peeters, Marc; Findlay, Michael; Pradeep, Virdee S.; Sharon, Love; Moschandreas, Joanna; Dutton, Peter; Gebski, Val; Gray, Alastair; Price, Dave; Bower, Geoff; Montazeri, Amir; Swinson, Daniel; Brown, Ewan; Wilson, Gregory; Lowndes, Sarah; Ricky A., Sharma und Gibbs, Peter
(2017):
Overall survival analysis of the FOXFIRE-SIRFLOX-FOXFIRE global prospective randomized studies of first-line selective internal radiotherapy (SIRT) in patients with liver metastases from colorectal cancer.
In: Annals of Oncology, Bd. 28
Hichert, Vivien; Scholl, Catharina; Steffens, Michael; Paul, Tanusree; Schumann, Christian; Rüdiger, Stefan; Böck, Stefan; Heinemann, Volker; Kächele, Volker; Seufferlein, Thomas und Stingl, Julia
(2017):
Predictive blood plasma biomarkers for EGFR inhibitor-induced skin rash.
In: Oncotarget, Bd. 8, Nr. 21: S. 35193-35204
Renfro, Lindsay A.; Goldberg, Richard M.; Grothey, Axel; Sobrero, Alberto; Adams, Richard; Seymour, Matthew T.; Heinemann, Volker; Schmoll, Hans-Joachim; Douillard, Jean-Yves; Hurwitz, Herbert; Fuchs, Charles S.; Diaz-Rubio, Eduardo; Porschen, Rainer; Tournigand, Christophe; Chibaudel, Benoist; Hoff, Paulo M.; Kabbinavar, Fairooz F.; Falcone, Alfredo; Tebbutt, Niall C.; Punt, Cornelis J. A.; Hecht, J. Randolph; Souglakos, John; Bokemeyer, Carsten; Cutsem, Eric van; Saltz, Leonard; Gramont, Aimery de und Sargent, Daniel J.
(2017):
Clinical Calculator for Early Mortality in Metastatic Colorectal Cancer: An Analysis of Patients From 28 Clinical Trials in the Aide et Recherche en Cancerologie Digestive Database.
In: Journal of Clinical Oncology, Bd. 35, Nr. 17: S. 1929-1937
Moehler, Markus; Mahlberg, Rolf; Heinemann, Volker; Obermannová, Radka; Kubala, Eugen; Melichar, Bohuslav; Weinmann, Arndt; Scigalla, Paul; Tesařová, Marietta; Janda, Petr; Hédouin-Biville, Fabienne und Mansoor, Wasat
(2017):
Phase I study of orally administered S-1 in combination with epirubicin and oxaliplatin in patients with advanced solid tumors and chemotherapy-naive advanced or metastatic esophagogastric cancer.
In: Gastric Cancer, Bd. 20, Nr. 2: S. 358-367
Tejpar, Sabine; Stintzing, Sebastian; Ciardiello, Fortunato; Tabernero, Josep; Cutsem, Eric van; Beier, Frank; Esser, Regina; Lenz, Heinz-Josef und Heinemann, Volker
(2017):
Prognostic and Predictive Relevance of Primary Tumor Location in Patients With RAS Wild-Type Metastatic Colorectal Cancer Retrospective Analyses of the CRYSTAL and FIRE-3 Trials.
In: Jama Oncology, Bd. 3, Nr. 2: S. 194-201
Modest, Dominik P.; Ricard, Ingrid; Heinemann, Volker; Hegewisch-Becker, S.; Schmiegel, W.; Porschen, R.; Stintzing, Sebastian; Graeven, U.; Arnold, D.; Fischer von Weikersthal, L.; Giessen-Jung, Clemens; Stahler, A.; Schmoll, H. J.; Jung, A.; Kirchner, T.; Tannapfel, A. und Reinacher-Schick, A.
(September 2016):
Outcome according to KRAS-, NRAS- and BRAF-mutation as well as KRAS mutation variants: pooled analysis of five randomized trials in metastatic colorectal cancer by the AIO colorectal cancer study group.
In: Annals of Oncology, Bd. 27, Nr. 9: S. 1746-1753
[PDF, 410kB]
Okazaki, Satoshi; Loupakis, Fotios; Stintzing, Sebastian; Cao, Shu; Zhang, Wu; Yang, Dongyun; Ning, Yan; Sunakawa, Yu; Stremitzer, Stefan; Matsusaka, Satoshi; Berger, Martin D.; Parekh, Anish; West, Jordan D.; Miyamoto, Yuji; Suenaga, Mitsukuni; Schirripa, Marta; Cremolini, Chiara; Falcone, Alfredo; Heinemann, Volker; DePaolo, R. William und Lenz, Heinz-Josef
(2016):
Clinical Significance of TLR1 I602S Polymorphism for Patients with Metastatic Colorectal Cancer Treated with FOLFIRI plus Bevacizumab.
In: Molecular Cancer therapeutics, Bd. 15, Nr. 7: S. 1740-1745
Renfro, Lindsay A.; Loupakis, Fotios; Adams, Richard A.; Seymour, Matthew T.; Heinemann, Volker; Schmoll, Hans-Joachim; Douillard, Jean-Yves; Hurwitz, Herbert; Fuchs, Charles S.; Diaz-Rubio, Eduardo; Porschen, Rainer; Tournigand, Christophe; Chibaudel, Benoist; Falcone, Alfredo; Tebbutt, Niall C.; Punt, Cornelis J. A.; Hecht, J. Randolph; Bokemeyer, Carsten; Cutsem, Eric van; Goldberg, Richard M.; Saltz, Leonard B.; Gramont, Aimery de; Sargent, Daniel J. und Lenz, Heinz-Josef
(2016):
Body Mass Index Is Prognostic in Metastatic Colorectal Cancer: Pooled Analysis of Patients From First-Line Clinical Trials in the ARCAD Database.
In: Journal of Clinical Oncology, Bd. 34, Nr. 2: S. 144-150
Hazel, Guy A. van; Heinemann, Volker; Sharma, Navesh K.; Findlay, Michael P. N.; Ricke, Jens; Peeters, Marc; Perez, David; Robinson, Bridget A.; Strickland, Andrew H.; Ferguson, Tom; Rodríguez, Javier; Kröning, Hendrik; Wolf, Ido; Ganju, Vinod; Walpole, Euan; Boucher, Eveline; Tichler, Thomas; Shacham-Shmueli, Einat; Powell, Alex; Eliadis, Paul; Isaacs, Richard; Price, David; Moeslein, Fred; Taieb, Julien; Bower, Geoff; Gebski, Val; Buskirk, Mark van; Cade, David N.; Thurston, Kenneth und Gibbs, Peter
(2016):
SIRFLOX: Randomized Phase III Trial Comparing First-Line mFOLFOX6 (Plus or Minus Bevacizumab) Versus mFOLFOX6 (Plus or Minus Bevacizumab) Plus Selective Internal Radiation Therapy in Patients With Metastatic Colorectal Cancer.
In: Journal of Clinical Oncology, Bd. 34, Nr. 15: S. 1723-1731
Cutsem, Eric van; Lenz, Heinz-Josef; Furuse, Junji; Tabernero, Josep; Heinemann, Volker; Ioka, Tatsuya; Bazin, Igor; Ueno, Makoto; Csõszi, Tibor; Wasan, Harpreet; Melichar, Bohuslav; Karasek, Petr; Macarulla, Teresa; Ponce, Carmen Guillen; Kalinka-Warzocha, Ewa; Horvath, Zsolt; Prenen, Hans; Schlichting, Michael; Mehdi, Fazal und Bendell, Johanna C.
(2016):
Evofosfamide (TH-302) in combination with gemcitabine in previously untreated patients with metastatic or locally advanced unresectable pancreatic ductal adenocarcinoma: Primary analysis of the randomized, double-blind phase III MAESTRO study.
In: Journal of Clinical Oncology, Bd. 34, Nr. 4
Okazaki, Satoshi; Stintzing, Sebastian; Heinemann, Volker; Cao, Shu; Zhang, Wu; Yang, Dongyun; Ning, Yan; Matsusaka, Satoshi; Berger, Martin D.; West, Jordan D.; Miyamoto, Yuji; Suenaga, Mitsukuni und Lenz, Heinz-Josef
(2016):
Association of TLR9 polymorphism with overall survival in metastatic colorectal cancer patients treated with FOLFIRI plus bevacizumab enrolled in FIRE3.
In: Journal of Clinical Oncology, Bd. 34, Nr. 4
Stintzing, Sebastian; Modest, Dominik Paul; Jung, Andreas; Kirchner, Thomas; Schäfer, Reinhold; Sers, Christine; Hildebrandt, Bert; Daum, Severin; Folprecht, Gunnar; Schuler, Martin H.; Kasper, Stefan; Trojan, Jorg; Jaeger, Dirk; Schulze-Bergkamen, Henning; Fischer von Weikersthal, Ludwig; Schalhorn, Alexander und Heinemann, Volker
(2016):
Differences in gene-expression in mCRC tissue samples with regard to tumor location and used chemotherapeutic substances: Data of the FIRE-1 study.
In: Journal of Clinical Oncology, Bd. 34, Nr. 4
Berger, Martin D.; Stintzing, Sebastian; Heinemann, Volker; Yang, Dongyun; Sunakawa, Yu; Ning, Yan; Matsusaka, Satoshi; Okazaki, Satoshi; Miyamoto, Yuji; Suenaga, Mitsukuni; West, Jordan David; Zhang, Wu; Petasis, Nicos und Lenz, Heinz-Josef
(2016):
Serum amyloid a (SAA-1) SNP rs12218 to predict outcome for mCRC patients treated with FOLFIRI and bevacizumab: Data from FIRE-3 trial.
In: Journal of Clinical Oncology, Bd. 34, Nr. 4
Modest, Dominik Paul; Stintzing, Sebastian; Fischer von Weikersthal, Ludwig; Sobrero, Alberto F.; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al-Batran, Salah-Eddin; Heintges, Tobias; Seipelt, Gernot; Lerchenmüller, Christian A.; Kahl, Christoph; Kullmann, Frank; Stauch, Martina; Scheithauer, Werner; Held, Swantje; Moehler, Markus H.; Jung, Andreas; Kirchner, Thomas und Heinemann, Volker
(2016):
Time-course evaluation of survival and treatment in FIRE-3 (AIO KRK0306, first-line therapy of KRAS wild-type metastatic colorectal cancer with FOLFIRI plus cetuximab or bevacizumab).
In: Journal of Clinical Oncology, Bd. 34, Nr. 4
Gibbs, Peter; Heinemann, Volker; Sharma, Navesh K.; Findlay, Michael P. N.; Ricke, Jens; Peeters, Marc; Perez, David; Robinson, Bridget Anne; Strickland, Andrew; Ferguson, Tom; Rodriguez, Javier; Kroening, Hendrik; Wolf, Ido; Ganju, Vinod; Walpole, Euan Thomas; Boucher, Eveline; Tichler, Thomas E.; Gebski, Val; Buskirk, Mark van und Hazel, Guy A. van
(2016):
SIRFLOX: Differences in site of first progression between mFOLFOX6 +/- bevacizumab (bev) versus mFOLFOX6 +/- bev plus selective internal radiation therapy (SIRT) in first-line patients (pts) with metastatic colorectal cancer (mCRC).
In: Journal of Clinical Oncology, Bd. 34, Nr. 4
Franko, Jan; Shi, Qian; Meyers, Jeffrey P.; Heinemann, Volker; Falcone, Alfredo; Tebbutt, Niall C.; Maughan, Tim; Seymour, Matthew; Saltz, Leonard; Tournigand, Christophe; Diaz-Rubio, Eduardo; Sougklakos, Ioannis; Chibaudel, Benoist; Moen, Joseph; Gramont, Aimery de; Adams, Richard A.; Sargent, Daniel J. und Grothey, Axel
(2016):
Prognostic value of isolated peritoneal versus other metastatic sites in colorectal cancer (CRC) patients treated by systemic chemotherapy: Findings from 9,265 pts in the ARCAD database.
In: Journal of Clinical Oncology, Bd. 34, Nr. 4
Koopman, Miriam; Shi, Qian; Goey, Kaitlyn K. H.; Green, Erin; Heinemann, Volker; Diaz-Rubio, Eduardo; Aranda, Enrique; Falcone, Alfredo; Gramont, Aimery de; Sargent, Daniel J. und Punt, Cornelis J. A.
(2016):
Prognostic value of primary tumor resection in synchronous metastatic colorectal cancer (mCRC): Individual patient data (IPD) analysis of first-line randomized trials from the ARCAD database.
In: Journal of Clinical Oncology, Bd. 34, Nr. 4
Steffens, Michael; Paul, Tanusree; Hichert, Vivien; Scholl, Catharina; Mallek, Dirk von; Stelzer, Christoph; Sörgel, Fritz; Reiser, Bärbel; Schumann, Christian; Rüdiger, Stefan; Boeck, Stefan; Heinemann, Volker; Kächele, Volker; Seufferlein, Thomas und Stingl, Julia
(2016):
Dosing to rash? - The role of erlotinib metabolic ratio from patient serum in the search of predictive biomarkers for EGFR inhibitor-mediated skin rash.
In: European Journal of Cancer, Bd. 55: S. 131-139
Kruger, Stephan; Haas, Michael; Burger, Philipp Johannes; Ormanns, Steffen; Modest, Dominik Paul; Westphalen, Christoph Benedikt; Michl, Marlies; Kleespies, Axel; Angele, Martin Kurt; Hartwig, Werner; Bruns, Christiane Josephine; Niyazi, Maximilian; Roeder, Falk; Kirchner, Thomas; Werner, Jens; Heinemann, Volker und Boeck, Stefan
(2016):
Isolated pulmonary metastases define a favorable subgroup in metastatic pancreatic cancer.
In: Pancreatology, Bd. 16, Nr. 4: S. 593-598
Stintzing, Sebastian; Modest, Dominik P.; Rossius, Lisa; Lerch, Markus M.; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al-Batran, Salah-Eddin; Heintges, Tobias; Lerchenmüller, Christian; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Stauch, Martina; Scheithauer, Werner; Held, Swantje; Giessen-Jung, Clemens; Moehler, Markus; Jagenburg, Andreas; Kirchner, Thomas; Jung, Andreas und Heinemann, Volker
(2016):
FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab for metastatic colorectal cancer (FIRE-3): a post-hoc analysis of tumour dynamics in the final RAS wild-type subgroup of this randomised open-label phase 3 trial.
In: Lancet Oncology, Bd. 17, Nr. 10: S. 1426-1434
Franko, Jan; Shi, Qian; Meyers, Jeffrey P.; Maughan, Timothy S.; Adams, Richard A.; Seymour, Matthew T.; Saltz, Leonard; Punt, Cornelis J. A.; Koopman, Miriam; Tournigand, Christophe; Tebbutt, Niall C.; Diaz-Rubio, Eduardo; Souglakos, John; Falcone, Alfredo; Chibaudel, Benoist; Heinemann, Volker; Moen, Joseph; Gramont, Aimery de; Sargent, Daniel J. und Grothey, Axel
(2016):
Prognosis of patients with peritoneal metastatic colorectal cancer given systemic therapy: an analysis of individual patient data from prospective randomised trials from the Analysis and Research in Cancers of the Digestive System (ARCAD) database.
In: Lancet Oncology, Bd. 17, Nr. 12: S. 1709-1719
Renz, Bernhard W.; Khalil, Philippe N.; Mikhailov, Michael; Graf, Sandra; Schiergens, Tobias S.; Niess, Hanno; Boeck, Stefan; Heinemann, Volker; Hartwig, Werner; Werner, Jens; Bruns, Christiane J. und Kleespies, Axel
(2016):
Pancreaticoduodenectomy for adenocarcinoma of the pancreatic head is justified in elderly patients: A Retrospective Cohort Study.
In: International Journal of Surgery, Bd. 28: S. 118-125
Kruger, Stephan; Haas, Michael; Burger, Philipp Johannes; Ormanns, Steffen; Modest, Dominik Paul; Westphalen, Christoph Benedikt; Kleespies, Axel; Angele, Martin Kurt; Hartwig, Werner; Bruns, Christiane Josephine; Kirchner, Thomas; Werner, Jens; Heinemann, Volker und Boeck, Stefan
(2016):
Acinar cell carcinoma of the pancreas: a rare disease with different diagnostic and therapeutic implications than ductal adenocarcinoma.
In: Journal of Cancer Research and Clinical Oncology, Bd. 142, Nr. 12: S. 2585-2591
Ormanns, Steffen; Haas, Michael; Baechmann, Sibylle; Altendorf-Hofmann, Annelore; Remold, Anna; Quietzsch, Detlef; Clemens, Michael R.; Bentz, Martin; Geissler, Michael; Lambertz, Helmut; Kruger, Stephan; Kirchner, Thomas; Heinemann, Volker und Boeck, Stefan
(2016):
Impact of SPARC expression on outcome in patients with advanced pancreatic cancer not receiving nab-paclitaxel: a pooled analysis from prospective clinical and translational trials.
In: British Journal of Cancer, Bd. 115, Nr. 12: S. 1520-1529
Butzke, Bettina; Oduncu, Fuat S.; Severin, Franziska; Pfeufer, Arne; Heinemann, Volker; Giessen-Jung, Clemens; Stollenwerk, Björn und Rogowski, Wolf H.
(2016):
The cost-effectiveness of UGT1A1 genotyping before colorectal cancer treatment with irinotecan from the perspective of the German statutory health insurance.
In: Acta Oncologica, Bd. 55, Nr. 3: S. 318-328
Mich, Marlies; Lehner, Sebastian; Paprottka, Philipp M.; Ilhan, Harun; Bartenstein, Peter; Heinemann, Volker; Boeck, Stefan; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624 und Fendler, Wolfgang P.
(2016):
Use of PERCIST for Prediction of Progression-Free and Overall Survival After Radioembolization for Liver Metastases from Pancreatic Cancer.
In: Journal of Nuclear Medicine, Bd. 57, Nr. 3: S. 355-360
Paprottka, Karolin Johanna; Lehner, Sebastian; Fendler, Wolfgang P.; Ilhan, Harun; Rominger, Axel; Sommer, Wieland; Clevert, Dirk-André; Winkel, Mark op den; Heinemann, Volker und Paprottka, Philipp Marius
(2016):
Reduced Periprocedural Analgesia After Replacement of Water for Injection with Glucose 5% Solution as the Infusion Medium for Y-90-Resin Microspheres.
In: Journal of Nuclear Medicine, Bd. 57, Nr. 11: S. 1679-1684
Niess, Hanno; Einem, Jobst C. von; Thomas, Michael N.; Michl, Marlies; Angele, Martin K.; Huss, Ralf; Günther, Christine; Nelson, Peter J.; Bruns, Christiane J. und Heinemann, Volker
(2015):
Treatment of advanced gastrointestinal tumors with genetically modified autologous mesenchymal stromal cells (TREAT-ME1): study protocol of a phase I/II clinical trial.
In: BMC Cancer
15:237
[PDF, 1MB]
Gamba, Sebastian; Camaj, Peter; Heinemann, Volker; Laubender, Rüdiger P.; Wang, Yan; Zhao, Yue; Stintzing, Sebastian; Giessen, Clemens; Boeck, Stefan; Haertl, Christoph; Bruns, Christiane J. und Modest, Dominik P.
(2015):
Effect of KRAS exon 2 mutations on antitumor activity of afatinib and gefitinib.
In: Anti-Cancer Drugs, Bd. 26, Nr. 4: S. 371-378
[PDF, 251kB]
Ormanns, Steffen; Siveke, Jens T.; Heinemann, Volker; Haas, Michael; Sipos, Bence; Schlitter, Anna Melissa; Esposito, Irene; Jung, Andreas; Laubender, Rüdiger P.; Kruger, Stephan; Vehling-Kaiser, Ursula; Winkelmann, Cornelia; Fischer von Weikersthal, Ludwig; Clemens, Michael R.; Gauler, Thomas C.; Märten, Angela; Geissler, Michael; Greten, Tim F.; Kirchner, Thomas und Boeck, Stefan
(2014):
pERK, pAKT and p53 as tissue biomarkers in erlotinib-treated patients with advanced pancreatic cancer: a translational subgroup analysis from AIO-PK0104.
In: BMC Cancer
14:624
[PDF, 408kB]
Modest, Dominik P.; Schulz, Christoph; Fischer von Weikersthal, Ludwig; Quietzsch, Detlef; Einem, J. C. von; Schalhorn, Andreas; Vehling-Kaiser, Ursula; Laubender, Rüdiger P.; Giessen, Clemens; Stintzing, Sebastian und Heinemann, Volker
(2014):
Outcome of patients with metastatic colorectal cancer depends on the primary tumor site (midgut vs. hindgut): analysis of the FIRE1-trial (FuFIRI or mIROX as first-line treatment).
In: Anticancer Drugs, Bd. 25, Nr. 2: S. 212-218
[PDF, 442kB]
Joka, Mareile; Boeck, Stefan; Zech, Christoph J.; Seufferlein, Thomas; Wichert, Götz von; Licht, Thomas; Krause, Annekatrin; Jauch, Karl-Walter; Heinemann, Volker und Bruns, Christiane J.
(2014):
Combination of antiangiogenic therapy using the mTOR-inhibitor everolimus and low-dose chemotherapy for locally advanced and/or metastatic pancreatic cancer: a dose-finding study.
In: Anti-Cancer Drugs, Bd. 25, Nr. 9: S. 1095-1101
[PDF, 364kB]
Kruger, Stephan; Angele, Martin K.; Reu, Simone; Sotlar, Karl; Graser, Anno; Haas, Michael; Albertsmeier, Markus; Stemmler, Hans-Joachim; Heinemann, Volker; Lindner, Lars H. und Böck, Stefan
(2014):
Complete pathological response to neoadjuvant pemetrexed/cisplatin in combination with regional hyperthermia in a patient with sarcomatoid peritoneal mesothelioma.
In: Anti-Cancer Drugs, Bd. 25, Nr. 7: S. 854-856
[PDF, 248kB]
Stintzing, Sebastian; Fischhaber, Doris; Mook, Charlotte; Modest, Dominik P.; Giessen, Clemens; Schulz, Christoph; Haas, Michael; Böck, Stefan; Michl, Marlies; Stemmler, Joachim; Laubender, Ruediger P. und Heinemann, Volker
(Oktober 2013):
Clinical relevance and utility of cetuximab-related changes in magnesium and calcium serum levels.
In: Anti-Cancer Drugs, Bd. 24, Nr. 9: S. 969-974
[PDF, 372kB]
Heinemann, Volker; Vehling-Kaiser, Ursula; Waldschmidt, Dirk; Kettner, Erika; Märten, Angela; Winkelmann, Cornelia; Klein, Stefan; Kojouharoff, Georgi; Gauler, Thomas C.; Fischer von Weikersthal, Ludwig; Clemens, Michael R.; Geissler, Michael; Greten, Tim F.; Hegewisch-Becker, Susanna; Rubanov, Oleg; Baake, Gerold; Höhler, Thomas; Ko, Yon D.; Jung, Andreas; Neugebauer, Sascha und Böck, Stefan
(Mai 2013):
Gemcitabine plus erlotinib followed by capecitabine versus capecitabine plus erlotinib followed by gemcitabine in advanced pancreatic cancer: final results of a randomised phase 3 trial of the `Arbeitsgemeinschaft Internistische Onkologie' (AIO-PK0104).
In: Gut, Bd. 62, Nr. 5: S. 751-759
[PDF, 468kB]
Holdenrieder, Stefan; Spelsberg, Fritz; Hatz, Rudolf; Waidelich, Raphaela; Untch, Michael; Hofmann, Karin; Wehnl, Birgit; Heinemann, Volker und Stieber, Petra
(2013):
Pattern of S100-release in benign and malignant diseases beside malignant melanoma/Freisetzung von S100 bei benignen und malignen Erkrankungen jenseits des malignen Melanoms.
In: Laboratoriumsmedizin - Journal of Laboratory Medicine, Bd. 37, Nr. 1: S. 21-28
[PDF, 521kB]
Giessen, Clemens; Di Gioia, Dorit; Huber, Bruno; Seppi, Bettina; Graser, Anno; Duerr, Hans Roland; Mayr, Doris; Kirchner, Thomas; Rosenwald, Andreas; Forstpointner, Roswitha; Heinemann, Volker; Bogner, Johannes R. und Ostermann, Helmut
(Februar 2012):
Primary effusion lymphoma (PEL) without effusion: a patient case report of a PEL solid variant.
In: Journal of clinical pathology, Bd. 65, Nr. 2: S. 189-90
[PDF, 530kB]
Modest, Dominik P.; Brodowicz, Thomas; Stintzing, Sebastian; Jung, Andreas; Neumann, Jens; Laubender, Ruediger P.; Ocvirk, Janja; Kurteva, Galina; Papai, Zsuzsanna; Knittelfelder, Regina; Kirchner, Thomas; Heinemann, Volker und Zielinski, Christoph C.
(2012):
Impact of the Specific Mutation in KRAS Codon 12 Mutated Tumors on Treatment Efficacy in Patients with Metastatic Colorectal Cancer Receiving Cetuximab-Based First-Line Therapy: A Pooled Analysis of Three Trials.
In: Oncology, Nr. 5: S. 241-247
[PDF, 200kB]
Schimanski, Carl Christoph; Möhler, Markus; Schön, Michael; Cutsem, Eric van; Greil, Richard; Bechstein, Wolf Otto; Hegewisch-Becker, Susanna; Wichert, Götz von; Vöhringer, Matthias; Heike, Michael; Heinemann, Volker; Peeters, Marc; Kanzler, Stephan; Kasper, Stefan; Overkamp, Friedrich; Schröder, Jan; Seehofer, Daniel; Kullmann, Frank; Linz, Bernhard; Schmidtmann, Irene; Smith-Machnow, Victoria; Gockel, Ines; Lang, Hauke und Galle, Peter R.
(2012):
LICC: L-BLP25 in patients with colorectal carcinoma after curative resection of hepatic metastases-a randomized, placebo-controlled, multicenter, multinational, double-blinded phase II trial.
In: BMC Cancer
12:144
[PDF, 1MB]
Giessen, Clemens; Fischer von Weikersthal, Ludwig; Hinke, Axel; Stintzing, Sebastian; Kullmann, Frank; Vehling-Kaiser, Ursula; Mayerle, Julia; Bangerter, Markus; Denzlinger, Claudio; Sieber, Markus; Teschendorf, Christian; Freiberg-Richter, Jens; Schulz, Christoph; Modest, Dominik Paul; Moosmann, Nicolas; Aubele, Philipp und Heinemann, Volker
(2011):
A randomized, phase III trial of capecitabine plus bevacizumab (Cape-Bev) versus capecitabine plus irinotecan plus bevacizumab (CAPIRI-Bev) in first-line treatment of metastatic colorectal cancer: The AIO KRK 0110 Trial/ML22011 Trial.
In: BMC Cancer
11:367
[PDF, 533kB]
Fietkau, Rainer; Heinemann, Volker; Oettle, Helmut; Knoefel, Wolfram Trudo und Tannapfel, Andrea
(2010):
Neue Daten zum Pankreaskarzinom.
In: Onkologie, Nr. 4: S. 31-35
[PDF, 378kB]
Stemmler, Hans-Joachim; Harbeck, Nadia; de Rivera, Isolde Groell; Kaiser, Ursula Vehling; Rauthe, Gerhard; Abenhardt, Wolfgang; Artmann, Almut; Sommer, Harald; Meerpohl, Hans-Gerd; Kiechle, Marion und Heinemann, Volker
(2010):
Prospective Multicenter Randomized Phase III Study of Weekly versus Standard Docetaxel (D2) for First-Line Treatment of Metastatic Breast Cancer.
In: Oncology, Nr. 3-4: S. 197-203
[PDF, 209kB]
Stemmler, Hans-Joachim; Harbeck, Nadia; de Rivera, Isolde Groell; Kaiser, Ursula Vehling; Rauthe, Gerhard; Abenhardt, Wolfgang; Artmann, Almut; Sommer, Harald; Meerpohl, Hans-Gerd; Kiechle, Marion und Heinemann, Volker
(2010):
Prospective Multicenter Randomized Phase III Study of Weekly versus Standard Docetaxel plus Doxorubicin (D4) for First-Line Treatment of Metastatic Breast Cancer.
In: Oncology, Nr. 3-4: S. 204-210
[PDF, 215kB]
Mihaljevic, Andre; Buechler, Peter; Harder, Jan; Hofheinz, Ralf; Gregor, Michael; Kanzler, Stephan; Schmiegel, Wolff; Heinemann, Volker; Endlicher, Esther; Kloeppel, Guenter; Seufferlein, Thomas und Geissler, Michael
(2009):
A prospective, non-randomized phase II trial of Trastuzumab and Capecitabine in patients with HER2 expressing metastasized pancreatic cancer.
In: BMC Surgery
9:1
[PDF, 284kB]
Boeck, Stefan; Wilkowski, Ralf; Bruns, Christiane J.; Issels, Rolf-Dieter; Schulz, Christoph; Moosmann, Nicolas; Laessig, Dorit; Haas, Michael; Golf, Alexander und Heinemann, Volker
(2007):
Oral capecitabine in gemcitabine-pretreated patients with advanced pancreatic cancer.
In: Oncology, Nr. 3-4: S. 221-227
[PDF, 330kB]
Laessig, D.; Stemmler, H. J.; Vehling-Kaiser, U.; Fasching, P. A.; Melchert, F.; Koelbl, H.; Stauch, M.; Maubach, P.; Scharl, A.; Morack, G.; Meerpohl, H.; Weber, B.; Kalischefski, B. und Heinemann, Volker
(2007):
Gemcitabine and carboplatin in intensively pretreated patients with metastatic breast cancer.
In: Oncology, Nr. 5-6: S. 407-414
[PDF, 150kB]
Stemmler, Hans-Joachim; Stieber, Petra; Laessig, Dorit; Bauerfeind, Ingo; Fasching, Peter; Beckmann, Matthias W.; Glattes, Margrit; Goldmann-Posch, Ursula; Hoffmann, Verena und Heinemann, Volker
(2006):
Follow-up for breast cancer - the patients' view.
In: Breast Care, Nr. 5: S. 316-319
[PDF, 74kB]
Stemmler, J.; Mair, W.; Stauch, M.; Papke, J.; Deutsch, G.; Abenhardt, Wolfgang; Dorn, B.; Kentenich, C.; Malekmohammadi, M.; Jackisch, C.; Leinung, S.; Brudler, O.; Vehling-Kaiser, U.; Stamp, J. und Heinemann, Volker
(2005):
High efficacy and low toxicity of weekly docetaxel given as first-line treatment for metastatic breast cancer.
In: Oncology, Nr. 1: S. 71-78
[PDF, 158kB]
Stemmler, J.; Stieber, P.; Szymala, A. M.; Schalhorn, A.; Schermuly, M. M.; Wilkowski, R.; Helmberger, T.; Lamerz, Rolf; Stoffregen, C.; Niebler, K.; Garbrecht, M. und Heinemann, Volker
(2003):
Are serial CA 19-9 kinetics helpful in predicting survival in patients with advanced or metastatic pancreatic cancer treated with gemcitabine and cisplatin?
In: Onkologie, Nr. 5: S. 462-467
[PDF, 115kB]
Diese Liste wurde am
Sat Dec 21 23:46:08 2024 CET
erstellt.