Anzahl der Publikationen: 186
2024
Yazdi, Mina; Pöhmerer, Jana; Hasanzadeh Kafshgari, Morteza; Seidl, Johanna; Grau, Melina; Höhn, Miriam; Vetter, Victoria; Hoch, Cosima C.; Wollenberg, Barbara; Multhoff, Gabriele; Bashiri Dezfouli, Ali und Wagner, Ernst ORCID: https://orcid.org/0000-0001-8413-0934
(2024):
In Vivo Endothelial Cell Gene Silencing by siRNA‐LNPs Tuned with Lipoamino Bundle Chemical and Ligand Targeting.
In: Small
[PDF, 6MB]
Germer, Janin; Lessl, Anna-Lina; Pöhmerer, Jana; Grau, Melina; Weidinger, Eric; Höhn, Miriam; Yazdi, Mina; Cappelluti, Martino Alfredo; Lombardo, Angelo; Lächelt, Ulrich und Wagner, Ernst ORCID: https://orcid.org/0000-0001-8413-0934
(2024):
Lipo-Xenopeptide Polyplexes for CRISPR/Cas9 based Gene editing at ultra-low dose.
In: Journal of Controlled Release, Bd. 370: S. 239-255
[PDF, 10MB]
2023
Thalmayr, Sophie; Grau, Melina; Peng, Lun; Pöhmerer, Jana; Wilk, Ulrich; Folda, Paul; Yazdi, Mina; Weidinger, Eric; Burghardt, Tobias; Höhn, Miriam; Wagner, Ernst ORCID: https://orcid.org/0000-0001-8413-0934 und Berger, Simone ORCID: https://orcid.org/0000-0002-3572-7205
(2023):
Molecular Chameleon Carriers for Nucleic Acid Delivery: The Sweet Spot between Lipoplexes and Polyplexes.
In: Advanced Materials, Bd. 35, Nr. 25
[PDF, 6MB]
2022
Kitzberger, Carolin; Spellerberg, Rebekka; Morath, Volker; Schwenk, Nathalie; Schmohl, Kathrin A.; Schug, Christina; Urnauer, Sarah; Tutter, Mariella; Eiber, Matthias; Schilling, Franz; Weber, Wolfgang A.; Ziegler, Sibylle; Bartenstein, Peter; Wagner, Ernst; Nelson, Peter J. und Spitzweg, Christine
(3. Mai 2022):
The sodium iodide symporter (NIS) as theranostic gene: its emerging role in new imaging modalities and non-viral gene therapy.
In: EJNMMI Research, Bd. 12
[PDF, 3MB]
Lin, Yi; Wilk, Ulrich; Poehmerer, Jana; Hörterer, Elisa; Höhn, Miriam; Luo, Xianjin; Mai, Hongcheng; Wagner, Ernst und Lächelt, Ulrich
(2022):
Folate Receptor-Mediated Delivery of Cas9 RNP for Enhanced Immune Checkpoint Disruption in Cancer Cells.
In: Small, Bd. 19, Nr. 2, 2205318
Spellerberg, Rebekka; Benli-Hoppe, Teoman; Kitzberger, Carolin; Hageneier, Mara; Schwenk, Nathalie; Öztürk, Özguer; Steiger, Katja; Multhoff, Gabriele; Eiber, Matthias; Schilling, Franz; Weber, Wolfgang A.; Kälin, Roland E.; Glass, Rainer; Nelson, Peter J.; Wagner, Ernst und Spitzweg, Christine
(2022):
Dual EGFR- and TfR-targeted gene transfer for sodium iodide symporter gene therapy of glioblastoma.
In: Molecular Therapy-Oncolytics, Bd. 27: S. 272-287
[PDF, 3MB]
Köhler, Bianca; Dubovik, Sviatlana; Hörterer, Elisa; Wilk, Ulrich; Stöckl, Jan Bernd; Tekarslan-Sahin, Hande; Ljepoja, Bojan; Paulitschke, Philipp; Fröhlich, Thomas; Wagner, Ernst und Roidl, Andreas
(2022):
Combating Drug Resistance by Exploiting miRNA-200c-Controlled Phase II Detoxification.
In: Cancers, Bd. 14, Nr. 22
[PDF, 4MB]
Lee, Myungeun; Rice-Boucher, Paul J.; Collins, Logan Thrasher; Wagner, Ernst; Aulisa, Lorenzo; Hughes, Jeffrey und Curiel, David T.
(2022):
A Novel Piggyback Strategy for mRNA Delivery Exploiting Adenovirus Entry Biology.
In: Viruses, Bd. 14, Nr. 10, 2169
Capeloa, Leon; Yazdi, Mina; Zhang, Heyang; Chen, Xiaobing; Nie, Yu; Wagner, Ernst; Lachelt, Ulrich und Barz, Matthias
(2022):
Cross-Linkable Polyion Complex Micelles from Polypept(o)ide-Based ABC-Triblock Copolymers for siRNA Delivery.
In: Macromolecular Rapid Communications, Bd. 43, Nr. 12, 2100698
Dezfouli, Ali Bashiri; Yazdi, Mina; Benmebarek, Mohamed-Reda; Schwab, Melissa; Michaelides, Stefanos; Micciche, Arianna; Geerts, Dirk; Stangl, Stefan; Klapproth, Sarah; Wagner, Ernst; Kobold, Sebastian und Multhoff, Gabriele
(2022):
CAR T Cells Targeting Membrane-Bound Hsp70 on Tumor Cells Mimic Hsp70-Primed NK Cells.
In: Frontiers in Immunology, Bd. 13, 883694
2021
Tutter, Mariella; Schug, Christina; Schmohl, Kathrin A.; Urnauer, Sarah; Kitzberger, Carolin; Schwenk, Nathalie; Petrini, Matteo; Zach, Christian; Ziegler, Sibylle; Bartenstein, Peter; Weber, Wolfgang A.; Multhoff, Gabriele; Wagner, Ernst; Lindner, Lars H.; Nelson, Peter J. und Spitzweg, Christine
(2021):
Regional Hyperthermia Enhances Mesenchymal Stem Cell Recruitment to Tumor Stroma: Implications for Mesenchymal Stem Cell-Based Tumor Therapy.
In: Molecular Therapy, Bd. 29, Nr. 2: S. 788-803
Spellerberg, Rebekka; Benli-Hoppe, Teoman; Kitzberger, Carolin; Berger, Simone; Schmohl, Kathrin A.; Schwenk, Nathalie; Yen, Hsi-Yu; Zach, Christian; Schilling, Franz; Weber, Wolfgang A.; Kalin, Roland E.; Glass, Rainer; Nelson, Peter J.; Wagner, Ernst und Spitzweg, Christine
(2021):
Selective sodium iodide symporter (NIS) gene therapy of glioblastoma mediated by EGFR-targeted lipopolyplexes.
In: Molecular Therapy-Oncolytics, Bd. 23: S. 432-446
Schirnding, Constantin von; Giopanou, Ioanna; Hermawan, Adam; Wehl, Lisa; Ntaliarda, Giannoula; Illes, Bernhard; Datz, Stefan; Geisslinger, Franz; Bartel, Karin; Sommer, Ann-Katrin; Lianou, Marina; Weiss, Veronika; Feckl, Johann; Vollmar, Angelika M.; Brauchle, Christoph; Stathopoulos, Georgios T.; Wagner, Ernst; Roidl, Andreas; Bein, Thomas und Engelke, Hanna
(2021):
Synergistic Combination of Calcium and Citrate in Mesoporous Nanoparticles Targets Pleural Tumors.
In: Chem, Bd. 7, Nr. 2: S. 480-494
Luo, Jie; Schmaus, Johannes; Cui, Mochen; Hörterer, Elisa; Wilk, Ulrich; Höhn, Miriam; Daether, Maike; Berger, Simone; Benli-Hoppe, Teoman; Peng, Lun und Wagner, Ernst
(2021):
Hyaluronate siRNA nanoparticles with positive charge display rapid attachment to tumor endothelium and penetration into tumors.
In: Journal of Controlled Release, Bd. 329: S. 919-933
Berger, Simone; Levacic, Ana Krhac; Hörterer, Elisa; Wilk, Ulrich; Benli-Hoppe, Teoman; Wang, Yanfang; Öztürk, Özgür; Luo, Jie und Wagner, Ernst
(2021):
Optimizing pDNA Lipo-polyplexes: A Balancing Act between Stability and Cargo Release.
In: Biomacromolecules, Bd. 22, Nr. 3: S. 1282-1296
Bashiri Dezfouli, Ali; Yazdi, Mina; Pockley, Alan Graham; Khosravi, Mohammad; Kobold, Sebastian; Wagner, Ernst und Multhoff, Gabriele
(2021):
NK Cells Armed with Chimeric Antigen Receptors (CAR): Roadblocks to Successful Development.
In: Cells, Bd. 10, Nr. 12, 3390
Büning, Hildegard; Fehse, Boris; Ivics, Zoltán; Kochanek, Stefan; Koehl, Ulrike; Kupatt, Christian; Mussolino, Claudio; Nettelbeck, Dirk M.; Schambach, Axel; Uckert, Wolfgang; Wagner, Ernst und Cathomen, Toni
(2021):
Gene Therapy “Made in Germany”: A Historical Perspective, Analysis of the Status Quo, and Recommendations for Action by the German Society for Gene Therapy.
In: Human Gene Therapy, Bd. 32, Nr. 19-20: S. 987-996
2020
Zhang, Peng; Zhang, Yu; Ding, Xiaoya; Shen, Wei; Li, Mingqian; Wagner, Ernst; Xiao, Chunsheng und Chen, Xuesi
(2020):
A Multistage Cooperative Nanoplatform Enables Intracellular Co-Delivery of Proteins and Chemotherapeutics for Cancer Therapy.
In: Advanced Materials, Bd. 32, Nr. 46, 2000013
Wang, Yanfang; Luo, Jie; Truebenbach, Ines; Reinhard, Soeren; Klein, Philipp Michael; Hoehn, Miriam; Kern, Sarah; Morys, Stephan; Loy, Dominik M.; Wagner, Ernst und Zhang, Wei
(2020):
Double Click-Functionalized siRNA Polyplexes for Gene Silencing in Epidermal Growth Factor Receptor-Positive Tumor Cells.
In: ACS Biomaterials Science & Engineering, Bd. 6, Nr. 2: S. 1074-1089
Haddick, Lisa; Zhang, Wei; Reinhard, Soeren; Moeller, Karin; Engelke, Hanna; Wagner, Ernst und Bein, Thomas
(2020):
Particle-Size-Dependent Delivery of Antitumoral miRNA Using Targeted Mesoporous Silica Nanoparticles.
In: Pharmaceutics, Bd. 12, Nr. 6, 505
Hirschle, Patrick; Hirschle, Christian; Böll, Konstantin; Döblinger, Markus; Höhn, Miriam; Tuffnell, Joshua M.; Ashling, Christopher W.; Keen, David A.; Bennett, Thomas D.; Rädler, Joachim O.; Wagner, Ernst; Peller, Michael ORCID: https://orcid.org/0000-0002-9333-2156; Laechelt, Ulrich und Wuttke, Stefan ORCID: https://orcid.org/0000-0002-6344-5782
(2020):
Tuning the Morphological Appearance of Iron(III) Fumarate: Impact on Material Characteristics and Biocompatibility.
In: Chemistry of Materials, Bd. 32, Nr. 6: S. 2253-2263
Kuhn, Jasmin; Lin, Yi; Levacic, Ana Krhac; Al Danaf, Nader; Peng, Lun; Hoehn, Miriam; Lamb, Don C.; Wagner, Ernst und Laechelt, Ulrich
(2020):
Delivery of Cas9/sgRNA Ribonucleoprotein Complexes via Hydroxystearyl Oligoamino Amides.
In: Bioconjugate Chemistry, Bd. 31, Nr. 3: S. 729-742
Tutter, Mariella; Schug, Christina; Schmohl, Kathrin A.; Urnauer, Sarah; Schwenk, Nathalie; Petrini, Matteo; Lokerse, Wouter J. M.; Zach, Christian; Ziegler, Sibylle; Bartenstein, Peter; Weber, Wolfgang A.; Wagner, Ernst; Lindner, Lars H.; Nelson, Peter J. und Spitzweg, Christine
(2020):
Effective control of tumor growth through spatial and temporal control of theranostic sodium iodide symporter (NIS) gene expression using a heat-inducible gene promoter in engineered mesenchymal stem cells.
In: Theranostics, Bd. 10, Nr. 10: S. 4490-4506
2019
Mastrella, Giorgia; Hou, Mengzhuo; Li, Min; Stöcklein, Veit M.; Zdouc, Nina; Vomar, Marie N. M.; Miletic, Hrvoje; Reinhard, Soeren; Herold-Mende, Christel C.; Kleber, Susanne; Eisenhut, Katharina; Gargiulo, Gaetano; Synowitz, Michael; Vescovi, Angelo L.; Harter, Patrick N.; Penninger, Josef M.; Wagner, Ernst; Mittelbronn, Michel; Bjerkvig, Rolf; Hambardzumyan, Dolores; Schueller, Ulrich; Tonn, Jörg-Christian; Radke, Josefine; Glass, Rainer und Kaelin, Roland E.
(2019):
Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma.
In: Cancer Research, Bd. 79, Nr. 9: S. 2298-2313
Urnauer, Sarah; Schmohl, Kathrin A.; Tutter, Mariella; Schug, Christina; Schwenk, Nathalie; Morys, Stephan; Ziegler, Sibylle; Bartenstein, Peter; Clevert, Dirk-Andre; Wagner, Ernst und Spitzweg, Christine
(2019):
Dual-targeted NIS polyplexes-a theranostic strategy toward tumors with heterogeneous receptor expression.
In: Gene Therapy, Bd. 26, Nr. 3-4: S. 93-108
Schug, Christina; Urnauer, Sarah; Jaeckel, Carsten; Schmohl, Kathrin A.; Tutter, Mariella; Steiger, Katja; Schwenk, Nathalie; Schwaiger, Markus; Wagner, Ernst; Nelson, Peter J. und Spitzweg, Christine
(2019):
TGFB1-driven mesenchymal stem cell-mediated NIS gene transfer.
In: Endocrine-Related Cancer, Bd. 26, Nr. 1: S. 89-101
Zimpel, Andreas; Al Danaf, Nader; Steinborn, Benjamin; Kuhn, Jasmin; Hoehn, Miriam; Bauer, Tobias; Hirschle, Patrick; Schrimpf, Waldemar; Engelke, Hanna; Wagner, Ernst; Barz, Matthias; Lamb, Don C.; Laechelt, Ulrich und Wuttke, Stefan
(2019):
Coordinative Binding of Polymers to Metal-Organic Framework Nanoparticles for Control of Interactions at the Biointerface.
In: ACS Nano, Bd. 13, Nr. 4: S. 3884-3895
Ljepoja, Bojan; Schreiber, Christoph; Gegenfurtner, Florian A.; Garcia-Roman, Jonathan; Köhler, Bianca; Zahler, Stefan; Rädler, Joachim O.; Wagner, Ernst und Roidl, Andreas
(2019):
Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A.
In: PLOS One
14(11), e0224314
[PDF, 2MB]
Sommer, Ann-Katrin; Falcenberg, Mathias; Ljepoja, Bojan; Fröhlich, Thomas; Arnold, Georg J.; Wagner, Ernst und Roidl, Andreas
(2019):
Downregulation of GRK5 hampers the migration of breast cancer cells.
In: Scientific Reports, Bd. 9, 15548
[PDF, 5MB]
Schug, Christina; Kitzberger, Carolin; Sievert, Wolfgang; Spellerberg, Rebekka; Tutter, Mariella; Schmohl, Kathrin A.; Eberlein, Bernadette; Biedermann, Tilo; Steiger, Katja; Zach, Christian; Schwaiger, Markus; Multhoff, Gabriele; Wagner, Ernst; Nelson, Peter J. und Spitzweg, Christine
(2019):
Radiation-Induced Amplification of TGFB1-Induced Mesenchymal Stem Cell-Mediated Sodium Iodide Symporter (NIS) Gene I-131 Therapy.
In: Clinical Cancer Research, Bd. 25, Nr. 19: S. 5997-6008
Kuhn, Jasmin; Klein, Philipp M.; Danaf, Nader al; Nordin, Joel Z.; Reinhard, Sören; Loy, Dominik M.; Höhn, Miriam; Andaloussi, Samir el; Lamb, Don C.; Wagner, Ernst; Aoki, Yoshitsugu; Lehto, Taavi und Lächelt, Ulrich
(2019):
Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles.
In: Advanced Functional Materials, Bd. 29, Nr. 48, 1906432
[PDF, 1MB]
Steinborn, Benjamin; Hirschle, Patrick; Höhn, Miriam; Bauer, Tobias; Barz, Matthias; Wuttke, Stefan; Wagner, Ernst und Lächelt, Ulrich
(2019):
Core‐Shell Functionalized Zirconium‐Pemetrexed Coordination Nanoparticles as Carriers with a High Drug Content.
In: Advanced Therapeutics, Bd. 2, Nr. 11
[PDF, 7MB]
Truebenbach, Ines; Zhang, Wei; Wang, Yanfang; Kern, Sarah; Hoehn, Miriam; Reinhard, Soeren; Gorges, Jan; Kazmaier, Uli und Wagner, Ernst
(2019):
Co-delivery of pretubulysin and siEG5 to EGFR overexpressing carcinoma cells.
In: International Journal of Pharmaceutics, Bd. 569, 118570
Schnitzler, Lukas G.; Junger, Stefanie; Loy, Dominik M.; Wagner, Ernst; Wixforth, Achim; Hoerner, Andreas; Laechelt, Ulrich und Westerhausen, Christoph
(2019):
Size tunable nanoparticle formation employing droplet fusion by acoustic streaming applied to polyplexes.
In: Journal of Physics D-Applied Physics, Bd. 52, Nr. 24, 244002
Pfitzer, Lisa; Moser, Christina; Gegenfurtner, Florian; Arner, Anja; Foerster, Florian; Atzberger, Carina; Zisis, Themistoklis; Kubisch-Dohmen, Rebekka; Busse, Johanna; Smith, Rebecca; Timinszky, Gyula; Kalinina, Olga V.; Müller, Rolf; Wagner, Ernst; Vollmar, Angelika M. und Zahler, Stefan
(2019):
Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy.
In: Cell Death & Disease, Bd. 10, UNSP 302
Kern, Sarah; Truebenbach, Ines; Hoehn, Miriam; Gorges, Jan; Kazmaier, Uli; Zahler, Stefan; Vollmar, Angelika M. und Wagner, Ernst
(2019):
Combined antitumoral effects of pretubulysin and methotrexate.
In: Pharmacology Research & Perspectives, Bd. 7, Nr. 1, UNSP e00460
2018
Qian, Min; Du, Yilin; Wang, Shanshan; Li, Chengyi; Jiang, Huiling; Shi, Wei; Chen, Jian; Wang, Yi; Wagner, Ernst und Huang, Rongqin
(2018):
Highly Crystalline Multicolor Carbon Nanodots for Dual-Modal Imaging-Guided Photothermal Therapy of Glioma.
In: ACS Applied Materials & Interfaces, Bd. 10, Nr. 4: S. 4031-4040
Deglmann, Claus J.; Blazkow-Schmalzbauer, Katarzyna; Moorkamp, Sarah; Wallmichrath, Jens; Giunta, Riccardo E.; Rogach, Andrey L.; Wagner, Ernst; Baumeister, Rüdiger G. und Ogris, Manfred
(2018):
In vivo tracking of adipose tissue grafts with cadmium-tel-luride quantum dots.
In: Archives of Plastic Surgery-Aps, Bd. 45, Nr. 2: S. 111-117
[PDF, 1MB]
Schug, Christina; Sievert, Wolfgang; Urnauer, Sarah; Müller, Andrea M.; Schmohl, Kathrin A.; Wechselberger, Alexandra; Schwenk, Nathalie; Lauber, Kirsten; Schwaiger, Markus; Multhoff, Gabriele; Wagner, Ernst; Nelson, Peter J. und Spitzweg, Christine
(2018):
External Beam Radiation Therapy Enhances Mesenchymal Stem Cell-Mediated Sodium-Iodide Symporter Gene Delivery.
In: Human Gene Therapy, Bd. 29, Nr. 11: S. 1287-1300
Klein, Philipp Michael; Klinker, Kristina; Zhang, Wei; Kern, Sarah; Kessel, Eva; Wagner, Ernst und Barz, Matthias
(2018):
Efficient Shielding of Polyplexes Using Heterotelechelic Polysarcosines.
In: Polymers, Bd. 10, Nr. 6, 689
[PDF, 2MB]
Ljepoja, Bojan; Garcia-Roman, Jonathan; Sommer, Ann-Katrin; Frohlich, Thomas; Arnold, Georg J.; Wagner, Ernst und Roidl, Andreas
(2018):
A proteomic analysis of an in vitro knock-out of miR-200c.
In: Scientific Reports, Bd. 8, 6927
[PDF, 3MB]
Hirschberger, Kristin; Jarzebinska, Anita; Kessel, Eva; Kretzschmann, Verena; Aneja, Manish K.; Dohmen, Christian; Herrmann-Janson, Annika; Wagner, Ernst; Plank, Christian und Rudolph, Carsten
(2018):
Exploring Cytotoxic mRNAs as a Novel Class of Anti-cancer Biotherapeutics.
In: Molecular Therapy-Methods & Clinical Development, Bd. 8: S. 141-151
[PDF, 1MB]
2017
Urnauer, Sarah; Klutz, Kathrin; Grünwald, Geoffrey K.; Morys, Stephan; Schwenk, Nathalie; Zach, Christian; Gildehaus, Franz-Josef; Rödl, Wolfgang; Ogris, Manfred; Wagner, Ernst und Spitzweg, Christine
(2017):
Systemic tumor-targeted sodium iodide symporter (NIS) gene therapy of hepatocellular carcinoma mediated by B6 peptide polyplexes.
In: Journal of Gene Medicine, Bd. 19, Nr. 5, e2957
Urnauer, Sarah; Müller, Andrea M.; Schug, Christina; Schmohl, Kathrin A.; Tutter, Mariella; Schwenk, Nathalie; Rödl, Wolfgang; Morys, Stephan; Ingrisch, Michäl; Bertram, Jens; Bartenstein, Peter; Clevert, Dirk-André; Wagner, Ernst und Spitzweg, Christine
(2017):
EGFR-targeted nonviral NIS gene transfer for bioimaging and therapy of disseminated colon cancer metastases.
In: Oncotarget, Bd. 8, Nr. 54: S. 92195-92208
Schmohl, Kathrin A.; Dolp, Patrick; Schug, Christina; Knoop, Kerstin; Klutz, Kathrin; Schwenk, Nathalie; Bartenstein, Peter; Nelson, Peter J.; Ogris, Manfred; Wagner, Ernst und Spitzweg, Christine
(2017):
Reintroducing the Sodium-Iodide Symporter to Anaplastic Thyroid Carcinoma.
In: Thyroid, Bd. 27, Nr. 12: S. 1534-1543
Morys, Stephan; Levacic, Ana Krhac; Urnauer, Sarah; Kempter, Susanne; Kern, Sarah; Rädler, Joachim O.; Spitzweg, Christine; Lächelt, Ulrich und Wagner, Ernst
(2017):
Influence of Defined Hydrophilic Blocks within Oligoaminoamide Copolymers: Compaction versus Shielding of pDNA Nanoparticles.
In: Polymers, Bd. 9, Nr. 4, 142
[PDF, 2MB]
Schmohl, Kathrin A.; Gupta, Aayush; Grünwald, Geoffrey K.; Trajkovic-Arsic, Marija; Klutz, Kathrin; Braren, Rickmer; Schwaiger, Markus; Nelson, Peter J.; Ogris, Manfred; Wagner, Ernst; Siveke, Jens T. und Spitzweg, Christine
(2017):
Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the theranostic sodium iodide symporter (NIS) gene.
In: Oncotarget, Bd. 8, Nr. 20: S. 33393-33404
[PDF, 5MB]
Lee, Dian-Jang; Kessel, Eva; Lehto, Taavi; Liu, Xueying; Yoshinaga, Naoto; Padari, Kart; Chen, Ying-Chen; Kempter, Susanne; Uchida, Satoshi; Rädler, Joachim O.; Pooga, Margus; Sheu, Ming-Thau; Kataoka, Kazunori und Wagner, Ernst
(2017):
Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia.
In: Bioconjugate Chemistry, Bd. 28, Nr. 9: S. 2393-2409
Nino-Pariente, Amaya; Arminan, Ana; Reinhard, Sören; Scholz, Claudia; Kos, Petra; Wagner, Ernst und Vicent, Maria J.
(2017):
Design of Poly-l-Glutamate-Based Complexes for pDNA Delivery (vol 10, 1700029, 2017).
In: Macromolecular Bioscience, Bd. 17, Nr. 10, 1700245
Heller, Philipp; Hobernik, Dominika; Lächelt, Ulrich; Schinnerer, Meike; Weber, Benjamin; Schmidt, Manfred; Wagner, Ernst; Bros, Matthias und Barz, Matthias
(2017):
Combining reactive triblock copolymers with functional cross-linkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines.
In: Journal of Controlled Release, Bd. 258: S. 146-160
Klein, Philipp M.; Reinhard, Sören; Zhang, Wei; Klinker, Kristina; Kern, Sarah; Kessel, Eva; Barz, Matthias und Wagner, Ernst
(2017):
Novel Poly(Sarcosine) Click Shielding Agents Improve Circulation of Redox-Sensitive siRNA Lipo-Polyplexes In Vivo.
In: Molecular therapy, Bd. 25, Nr. 5: S. 144
Trübenbach, Ines; Gorges, Jan; Kuhn, Jasmin; Kern, Sarah; Baratti, Emanuele; Kazmaier, Uli; Wagner, Ernst und Lächelt, Ulrich
(2017):
Sequence-Defined Oligoamide Drug Conjugates of Pretubulysin and Methotrexate for Folate Receptor Targeted Cancer Therapy.
In: Macromolecular Bioscience, Bd. 17, Nr. 10, 1600520
Wang, Shanshan; Li, Chengyi; Qian, Min; Jiang, Huiling; Shi, Wei; Chen, Jian; Lächelt, Ulrich; Wagner, Ernst; Lu, Weiyue; Wang, Yi und Huang, Rongqin
(2017):
Augmented glioma-targeted theranostics using multifunctional polymer-coated carbon nanodots.
In: Biomaterials, Bd. 141: S. 29-39
Wang, Shanshan; Reinhard, Sören; Li, Chengyi; Qian, Min; Jiang, Huiling; Du, Yilin; Lächelt, Ulrich; Lu, Weiyue; Wagner, Ernst und Huang, Rongqin
(2017):
Antitumoral Cascade-Targeting Ligand for IL-6 Receptor-Mediated Gene Delivery to Glioma.
In: Molecular therapy, Bd. 25, Nr. 7: S. 1556-1566
Deglmann, Claus J.; Błażków-Schmalzbauer, Katarzyna; Moorkamp, Sarah; Susha, Andrei S.; Herrler, Tanja; Giunta, Riccardo E.; Wagner, Ernst; Rogach, Andrey L.; Baumeister, Ruediger G. und Ogris, Manfred
(2017):
Cadmium Telluride Quantum Dots as a Fluorescence Marker for Adipose Tissue Grafts.
In: Annals of Plastic Surgery, Bd. 78, Nr. 2: S. 217-222
[PDF, 586kB]
Röder, Ruth; Preiß, Tobias; Hirschle, Patrick; Steinborn, Benjamin; Zimpel, Andreas; Höhn, Miriam; Rädler, Joachim O.; Bein, Thomas; Wagner, Ernst; Wuttke, Stefan und Lächelt, Ulrich
(2017):
Multifunctional Nanoparticles by Coordinative Self-Assembly of His Tagged Units with Metal Organic Frameworks.
In: Journal of the American Chemical Society, Bd. 139, Nr. 6: S. 2359-2368
Tippelt, Rudolf
(2017):
Soziokulturelle Milieus.
In: Wagner, Ernst; Wenrich, Rainer und Ratzel, Ann-Jasmin (Hrsg.):
Diversity im Kunstunterricht ; Modelle inter- und transkultureller Vermittlungspraxis. München: kopaed. S. 210-218
Kiel, Ewald
(2017):
Der Umgang mit Kultur im Unterricht.
In: Wagner, Ernst; Wenrich, Rainer und Ratzel, Ann-Jasmin (Hrsg.):
Diversity im Kunstunterricht ; Modelle inter- und transkultureller Vermittlungspraxis. München: kopaed. S. 240-248
2016
Möller, Karin; Müller, Katharina; Engelke, Hanna; Bräuchle, Christoph; Wagner, Ernst und Bein, Thomas
(2016):
Highly efficient siRNA delivery from core – shell mesoporous silica nanoparticles with
multifunctional polymer caps.
In: Nanoscale, Bd. 8, Nr. 7, 4007
[PDF, 4MB]
Klein, Philipp M.; Reinhard, Sören; Lee, Dian-Jang; Müller, Katharina; Ponader, Daniela; Hartmann, Laura und Wagner, Ernst
(2016):
Precise redox-sensitive cleavage sites for improved bioactivity of siRNA lipopolyplexes.
In: Nanoscale, Bd. 8, Nr. 42: S. 18098-18104
[PDF, 1MB]
Westerhausen, Christoph; Schnitzler, Lukas G.; Wendel, Dominik; Krzyszton, Rafal; Lächelt, Ulrich; Wagner, Ernst; Rädler, Joachim O. und Wixforth, Achim
(2016):
Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles.
In: Micromachines, Bd. 7, Nr. 9, 150
[PDF, 4MB]
Urnauer, Sarah; Morys, Stephan; Levacic, Ana Krhac; Müller, Andrea M.; Schug, Christina; Schmohl, Kathrin A.; Schwenk, Nathalie; Zach, Christian; Carlsen, Janette; Bartenstein, Peter; Wagner, Ernst und Spitzweg, Christine
(2016):
Sequence-defined cMET/HGFR-targeted Polymers as Gene Delivery Vehicles for the Theranostic Sodium Iodide Symporter (NIS) Gene.
In: Molecular therapy, Bd. 24, Nr. 8: S. 1395-1404
Müller, Andrea M.; Schmohl, Kathrin A.; Knoop, Kerstin; Schug, Christina; Urnauer, Sarah; Hagenhoff, Anna; Clevert, Dirk-André; Ingrisch, Michael; Niess, Hanno; Carlsen, Janette; Zach, Christian; Wagner, Ernst; Bartenstein, Peter; Nelson, Peter J. und Spitzweg, Christine
(2016):
Hypoxia-targeted I-131 therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated sodium iodide symporter gene delivery.
In: Oncotarget, Bd. 7, Nr. 34: S. 54795-54810
Liu, Xiaowen; Zhang, Peng; He, Dongsheng; Rödl, Wolfgang; Preiß, Tobias; Rädler, Joachim O.; Wagner, Ernst und Lächelt, Ulrich
(2016):
pH-Reversible Cationic RNase A Conjugates for Enhanced Cellular Delivery and Tumor Cell Killing.
In: Biomacromolecules, Bd. 17, Nr. 1: S. 173-182
Zimpel, Andreas; Preiß, Tobias; Röder, Ruth; Engelke, Hanna; Ingrisch, Michael; Peller, Michael; Rädler, Joachim O.; Wagner, Ernst; Bein, Thomas; Lächelt, Ulrich und Wuttke, Stefan
(2016):
Imparting Functionality to MOF Nanoparticles by External Surface Selective Covalent Attachment of Polymers.
In: Chemistry of Materials, Bd. 28, Nr. 10: S. 3318-3326
Jiang, Qian; Yue, Dong; Nie, Yu; Xu, Xianghui; He, Yiyan; Zhang, Shiyong; Wagner, Ernst und Gu, Zhongwei
(2016):
Specially-Made Lipid-Based Assemblies for Improving Transmembrane Gene Delivery: Comparison of Basic Amino Acid Residue Rich Periphery.
In: Molecular Pharmaceutics, Bd. 13, Nr. 6: S. 1809-1821
Zhang, Wei; Müller, Katharina; Kessel, Eva; Reinhard, Sören; He, Dongsheng; Klein, Philipp M.; Höhn, Miriam; Rödl, Wolfgang; Kempter, Susanne und Wagner, Ernst
(2016):
Targeted siRNA Delivery Using a Lipo-Oligoaminoamide Nanocore with an Influenza Peptide and Transferrin Shell.
In: Advanced Healthcare Materials, Bd. 5, Nr. 12: S. 1493-1504
Lee, Dian-Jang; Kessel, Eva; Edinger, Daniel; He, Dongsheng; Klein, Philipp M.; Voith von Voithenberg, Lena; Lamb, Don C.; Lächelt, Ulrich; Lehto, Taavi und Wagner, Ernst
(2016):
Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand.
In: Biomaterials, Bd. 77: S. 98-110
Lee, Dian-Jang; He, Dongsheng; Kessel, Eva; Padari, Kärt; Kempter, Susanne; Lächelt, Ulrich; Rädler, Joachim O.; Pooga, Margus und Wagner, Ernst
(2016):
Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes.
In: Journal of Controlled Release, Bd. 244: S. 280-291
Sommer, Ann-Katrin; Hermawan, Adam; Mickler, Frauke Martina; Ljepoja, Bojan; Knyazev, Pjotr; Bräuchle, Christoph; Ullrich, Axel; Wagner, Ernst und Roidl, Andreas
(2016):
Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases.
In: Oncotarget, Bd. 7, Nr. 31: S. 50461-50476
2015
Niedermayer, Stefan; Weiss, Veronika; Herrmann, Annika; Schmidt, Alexandra; Datz, Stefan; Müller, Katharina; Wagner, Ernst; Bein, Thomas und Bräuchle, Christoph
(2015):
Multifunctional polymer-capped mesoporous silica nanoparticles for pH-responsive targeted drug delivery.
In: Nanoscale, Bd. 7, Nr. 17: S. 7953-7964
[PDF, 2MB]
2014
Kopp, Florian; Hermawan, Adam; Oak, Prajakta Shirish; Ulaganathan, Vijay Kumar; Herrmann, Annika; Elnikhely, Nefertiti; Thakur, Chitra; Xiao, Zhiguang; Knyazev, Pjotr; Ataseven, Beyhan; Savai, Rajkumar; Wagner, Ernst und Roidl, Andreas
(2014):
Sequential Salinomycin Treatment Results in Resistance Formation through Clonal Selection of Epithelial-Like Tumor Cells.
In: Translational Oncology, Bd. 7, Nr. 6: S. 702-711
[PDF, 1MB]
Menhofer, Magdalena H.; Kubisch, Rebekka; Schreiner, Laura; Zorn, Matthias; Foerster, Florian; Mueller, Rolf; Rädler, Joachim O.; Wagner, Ernst; Vollmar, Angelika M. und Zahler, Stefan
(2014):
The Actin Targeting Compound Chondramide Inhibits Breast Cancer Metastasis via Reduction of Cellular Contractility.
In: PLOS ONE
9(11), e112542
[PDF, 1MB]
Kos, Petra; Lächelt, Ulrich; Herrmann, Annika; Mickler, Frauke M.; Krhač Levačić, Ana; Morys, Stephan; Bräuchle, Christoph und Wagner, Ernst
(2014):
Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer.
In: Nanoscale, Bd. 7, Nr. 12: S. 5350-5362
[PDF, 0B]
2013
2012
Dohmen, Christian; Edinger, Daniel; Fröhlich, Thomas; Schreiner, Laura; Lächelt, Ulrich; Troiber, Christina; Rädler, Joachim O.; Hadwiger, Philipp; Vornlocher, Hans-Peter und Wagner, Ernst
(2012):
Nanosized Multifunctional Polyplexes for Receptor-Mediated SiRNA Delivery.
In: ACS Nano, Bd. 6, Nr. 6: S. 5198-5208
[PDF, 660kB]
Terziyska, Nadia; Castro Alves, Catarina; Groiss, Volker; Schneider, Katja; Farkasova, Katarina; Ogris, Manfred; Wagner, Ernst; Ehrhardt, Harald; Brentjens, Renier J.; zur Stadt, Udo; Horstmann, Martin; Quintanilla-Martinez, Leticia und Jeremias, Irmela
(2012):
In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice.
In: PLOS ONE
7(12), e52798
[PDF, 1MB]
Martin, Irene; Dohmen, Christian; Mas-Moruno, Carlos; Troiber, Christina; Kos, Petra; Schaffert, David; Lächelt, Ulrich; Teixido, Meritxell; Günther, Michael; Kessler, Horst; Giralt, Ernest und Wagner, Ernst
(2012):
Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery.
In: Organic and Biomolecular Chemistry, Bd. 10, Nr. 16: S. 3258-3268
[PDF, 1MB]
2011
Dussmann, Philipp; Pagel, Judith I.; Vogel, Sabina; Magnusson, Terese; Zimmermann, Rene; Wagner, Ernst; Schaper, Wolfgang; Ogris, Manfred und Deindl, Elisabeth
(2011):
Live in vivo imaging of Egr-1 promoter activity during neonatal development, liver regeneration and wound healing.
In: BMC Developmental Biology
11:28
[PDF, 2MB]
2008
2006
1994
Curiel, Tyler J.; Cook, Deborah R.; Bogedain, Christoph; Jilg, Wolfgang; Harrison, Gail S.; Cotten, Matt; Curiel, David T. und Wagner, Ernst
(1994):
Efficient Foreign Gene Expression in Epstein-Barr Virus-Transformed Human B-Cells.
In: Virology, Bd. 198, Nr. 2: S. 577-585
[PDF, 561kB]
Noe, Christian R.; Knollmüller, Max; Miculka, Christian; Dungler, Karin; Wagner, Ernst und Ettmayer, Peter
(1994):
Chirale Lactole, XI. Eine Methode zur Bestimmung der Absolutkonfiguration chiraler Alkanole.
In: Chemische Berichte, Bd. 127, Nr. 5: S. 887-892
[PDF, 1MB]
Zatloukal, Kurt; Cotten, Matt; Berger, Manfred; Schmidt, Walter; Wagner, Ernst und Birnstiel, Max L.
(1994):
In vivo production of human factor VII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery.
In: Proceedings of the National Academy of Science of the U S A, Bd. 91, Nr. 11: S. 5148-5152
[PDF, 1MB]
Cheng, Qi; Cant, Charles; Moll, Thomas; Hofer-Warbinek, Renate; Wagner, Ernst; Birnstiel, Max L.; Bach, Fritz H. und Martin, Rainer de
(1994):
NK-kappa B subunit-specific regulation of the I kappa B alpha promoter.
In: Journal of Biological Chemistry, Bd. 269: S. 13551-13557
[PDF, 2MB]
Wagner, Ernst; Cotten, Matt; Plank, Christian; Mechtler, Karl; Zatloukal, Kurt und Birnstiel, Max L.
(1994):
Receptor-mediated gene delivery into mammalian cells.
In: Spier, R. E. (Hrsg.):
Animal cell technology: Products of today, prospects for tomorrow. Oxford: Butterworth Heinemann. S. 30-34
[PDF, 1MB]
Wagner, Ernst; Buschle, M.; Cotten, Matt; Plank, Christian; Zauner, W. und Birnstiel, Max L.
(1994):
Synthetic virus-like gene delivery systems.
21. International Symposium on controlled release of bioactive materials, Nizza, 27-30 Juni 1994.
Guy, Richard H. (Hrsg.):
In: Proceedings of the 21. International Symposium on controlled release of bioactive materials,
Deerfield, Ill.: Controlled Release Society. S. 3-4
[PDF, 432kB]
Thurnher, Martin; Wagner, Ernst; Clausen, Henrik; Mechtler, Karl; Rusconi, Sandro; Dinter, André; Birnstiel, Max L.; Berger, Eric G. und Cotten, Matt
(1994):
Carbohydrate receptor-mediated gene transfer to human T leukaemic cells.
In: Glycobiology, Bd. 4: S. 429-435
[PDF, 3MB]
Maass, Gerd; Zatloukal, Kurt; Schmidt, Walter; Berger, M.; Cotten, Matt; Wagner, Ernst; Birnstiel, Max L. und Buschle, M.
(1994):
The generation of tumor vaccines by adenovirus-enhanced transfection of cytokine genes into tumor cells.
In: Skouteris, George G. (Hrsg.):
Liver carcinogenesis. Berlin u.a.: Springer. S. 467-479
[PDF, 1MB]
Frank, Sasa; Krasznai, Krisztina; Durovic, Srdan; Lobentanz, Eva-Maria; Dieplinger, Hans; Wagner, Ernst; Zatloukal, Kurt; Cotten, Matt; Utermann, Gerd; Kostner, Gerd M. und Zechner, Rudolf
(1994):
High-Level Expression of Various Apolipoprotein (a) Isoforms by "Transferrinfection". The Role of Kringle IV Sequences in the Extracellular Association with Low-Density Lipoprotein.
In: Biochemistry, Bd. 33, Nr. 40: S. 12329-12339
[PDF, 3MB]
Zatloukal, Kurt; Schneeberger, A.; Berger, M.; Koszik, F.; Schmidt, Walter; Wagner, Ernst; Cotten, Matt; Buschle, M.; Maass, Gerd; Stingl, Georg und Birnstiel, Max L.
(1994):
Genetic modification of cells by receptor-mediated adenovirus-augmented gene delivery. A new approach for immunotherapy of cancer.
In: Verhandlungen der Deutschen Gesellschaft für Pathologie, Bd. 78: S. 171-176
[PDF, 3MB]
Cook, Deborah R.; Maxwell, I. H.; Glode, L. M.; Maxwell, F.; Stevens, J. O.; Purner, M. B.; Wagner, Ernst; Curiel, David T. und Curiel, Tyler J.
(1994):
Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate.
In: Cancer Biotherapy, Bd. 9: S. 131-141
[PDF, 1MB]
1993
Gao, L.; Wagner, Ernst; Cotten, Matt; Agarwal, Santosh; Harris, C. E.; Romer, M.; Miller, L.; Hu, P.-C. und Curiel, David T.
(1993):
Direct in vivo gene transfer to the airway epithelium employing adenovirus-polylysine-DNA complexes.
In: Human Gene Therapy, Bd. 4: S. 17-24
[PDF, 6MB]
1992
Curiel, David T.; Wagner, Ernst; Cotten, Matt; Birnstiel, Max L.; Agarwal, Santosh; Li, C.-M.; Loechel, S. und Hu, P.-C.
(1992):
High-efficiency gene transfer by adenovirus coupled to DNA-polylysine complexes.
In: Human Gene Therapy, Bd. 3, Nr. 2: S. 147-154
[PDF, 1MB]
Wagner, Ernst; Zatloukal, Kurt; Cotten, Matt; Kirlappos, Helen; Mechtler, Karl; Curiel, David T. und Birnstiel, Max L.
(1992):
Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.
In: Proceedings of the National Academy of Science of the U S A, Bd. 89, Nr. 13: S. 6099-6103
[PDF, 1MB]
Zatloukal, Kurt; Wagner, Ernst; Cotten, Matt; Phillips, Stephen; Plank, Christian; Steinlein, Peter; Curiel, David T. und Birnstiel, Max L.
(1992):
Transferrinfection. A Highly Efficient Way to Express Gene Constructs in Eukaryotic Cells.
In: Annals of the New York Academy of Sciences, Bd. 660, Nr. 1: S. 136-153
[PDF, 2MB]
1991
Cotten, Matt; Oberhauser, Berndt; Brunar, Helmut; Holzner, Armin; Issakides, Georg; Noe, Christian R.; Schaffner, Gotthold; Wagner, Ernst und Birnstiel, Max L.
(1991):
2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event.
In: Nucleic Acids Research, Bd. 19: S. 2629-2635
[PDF, 6MB]
Wagner, Ernst; Oberhauser, Berndt; Holzner, Armin; Brunar, Helmut; Issakides, Georg; Schaffner, Gotthold; Cotten, Matt; Knollmüller, Max und Noe, Christian R.
(1991):
A simple procedure for the preparation of protected 2'-O-methyl or 2'-O-ethyl ribonucleoside-3'-O-phosphoramidites.
In: Nucleic Acids Research, Bd. 19: S. 5965-5971
[PDF, 752kB]
Noe, Christian R.; Knollmüller, Max; Steinbauer, Gerhard; Wagner, Ernst; Kürner, H.; Ettmayer, Peter und Völlenkle, Horst
(1991):
Eine einfache Methode zur Steuerung der Reduktion von α-Alkoxy-carbonylverbindungen.
In: Monatshefte für Chemie / Chemical Monthly, Bd. 122, Nr. 4: S. 299-317
[PDF, 1MB]
1990
Müller, Daniel; Pitsch, Stefan; Kittaka, Atsushi; Wagner, Ernst; Wintner, Claude E. und Eschenmoser, Albert
(1990):
Chemie von a-Aminonitrilen. Aldomerisierung von Glycolaldehyd-phosphat zu racemischen Hexose-2,4,6-triphosphaten und (in Gegenwart von Formaldehyd) racemischen Pentose-2,4-diphosphaten: rac-Allose-2,4,6-triphosphat und rac-Ribose-2,4-diphosphat sind die Reaktionshauptprodukte.
In: Helvetica Chimica Acta, Bd. 73, Nr. 5: S. 1410-1468
[PDF, 3MB]
Cotten, Matt; Längle-Rouault, Francoise; Kirlappos, Helen; Wagner, Ernst; Mechtler, Karl; Zenke, Martin; Beug, Hartmut und Birnstiel, Max L.
(1990):
Transferrin-polycation-mediated introduction of DNA into human leukemic cells. Stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.
In: Proceedings of the National Academy of Science of the U S A, Bd. 87, Nr. 11: S. 4033-4037
[PDF, 1MB]
1986
Noe, Christian R.; Knollmüller, Max; Oberhauser, Berndt; Steinbauer, Gerhard und Wagner, Ernst
(1986):
Chirale Lactole, VI. Eine Methode zur Bestimmung der Absolutkonfiguration chiraler alpha-hydroxysubstituierter Nitrile, Alkine und Aldehyde.
In: Chemische Berichte, Bd. 119, Nr. 2: S. 729-743
[PDF, 39MB]
1985
Noe, Christian R.; Knollmüller, Max; Wagner, Ernst und Völlenkle, Horst
(1985):
Chirale Lactole, IV. Selektivitäten bei Acetalisierungsreaktionen enantiomerenreiner Lactole am Beispiel von Octahydro-8,9,9-trimethyl-5,8-methano-2H-1-benzopyran-2-ol.
In: Chemische Berichte, Bd. 118, Nr. 5: S. 1733-1745
[PDF, 2MB]
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