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Anzahl der Publikationen: 175

2023

Thalmayr, Sophie; Grau, Melina; Peng, Lun; Pöhmerer, Jana; Wilk, Ulrich; Folda, Paul; Yazdi, Mina; Weidinger, Eric; Burghardt, Tobias; Höhn, Miriam; Wagner, Ernst ORCID logoORCID: https://orcid.org/0000-0001-8413-0934 und Berger, Simone ORCID logoORCID: https://orcid.org/0000-0002-3572-7205 (2023): Molecular Chameleon Carriers for Nucleic Acid Delivery: The Sweet Spot between Lipoplexes and Polyplexes. In: Advanced Materials, Bd. 35, Nr. 25 [PDF, 6MB]

2022

Kitzberger, Carolin; Spellerberg, Rebekka; Morath, Volker; Schwenk, Nathalie; Schmohl, Kathrin A.; Schug, Christina; Urnauer, Sarah; Tutter, Mariella; Eiber, Matthias; Schilling, Franz; Weber, Wolfgang A.; Ziegler, Sibylle; Bartenstein, Peter; Wagner, Ernst; Nelson, Peter J. und Spitzweg, Christine (3. Mai 2022): The sodium iodide symporter (NIS) as theranostic gene: its emerging role in new imaging modalities and non-viral gene therapy. In: EJNMMI Research, Bd. 12 [PDF, 3MB]

Köhler, Bianca; Dubovik, Sviatlana; Hörterer, Elisa; Wilk, Ulrich; Stöckl, Jan Bernd; Tekarslan-Sahin, Hande; Ljepoja, Bojan; Paulitschke, Philipp; Fröhlich, Thomas; Wagner, Ernst und Roidl, Andreas (2022): Combating Drug Resistance by Exploiting miRNA-200c-Controlled Phase II Detoxification. In: Cancers, Bd. 14, Nr. 22 [PDF, 4MB]

Steffens, Ricarda Carolin und Wagner, Ernst (2022): Directing the Way-Receptor and Chemical Targeting Strategies for Nucleic Acid Delivery. In: Pharmaceutical Research, Bd. 40, Nr. 1: S. 47-76 [PDF, 2MB]

Spellerberg, Rebekka; Benli-Hoppe, Teoman; Kitzberger, Carolin; Hageneier, Mara; Schwenk, Nathalie; Öztürk, Özguer; Steiger, Katja; Multhoff, Gabriele; Eiber, Matthias; Schilling, Franz; Weber, Wolfgang A.; Kälin, Roland E.; Glass, Rainer; Nelson, Peter J.; Wagner, Ernst und Spitzweg, Christine (2022): Dual EGFR- and TfR-targeted gene transfer for sodium iodide symporter gene therapy of glioblastoma. In: Molecular Therapy-Oncolytics, Bd. 27: S. 272-287 [PDF, 3MB]

Berger, Simone ORCID logoORCID: https://orcid.org/0000-0002-3572-7205; Berger, Martin ORCID logoORCID: https://orcid.org/0000-0002-0926-653X; Bantz, Christoph; Maskos, Michael und Wagner, Ernst ORCID logoORCID: https://orcid.org/0000-0001-8413-0934 (2022): Performance of nanoparticles for biomedical applications: The in vitro/in vivo discrepancy. In: Biophysics Reviews, Bd. 3, Nr. 1, 011303

2021

Freitag, Franziska und Wagner, Ernst (2021): Optimizing synthetic nucleic acid and protein nanocarriers: The chemical evolution approach. In: Advanced Drug Delivery Reviews, Bd. 168: S. 30-54

Büning, Hildegard; Fehse, Boris; Ivics, Zoltán; Kochanek, Stefan; Koehl, Ulrike; Kupatt, Christian; Mussolino, Claudio; Nettelbeck, Dirk M.; Schambach, Axel; Uckert, Wolfgang; Wagner, Ernst und Cathomen, Toni (2021): Gene Therapy “Made in Germany”: A Historical Perspective, Analysis of the Status Quo, and Recommendations for Action by the German Society for Gene Therapy. In: Human Gene Therapy, Bd. 32, Nr. 19-20: S. 987-996

Bashiri Dezfouli, Ali; Yazdi, Mina; Pockley, Alan Graham; Khosravi, Mohammad; Kobold, Sebastian; Wagner, Ernst und Multhoff, Gabriele (2021): NK Cells Armed with Chimeric Antigen Receptors (CAR): Roadblocks to Successful Development. In: Cells, Bd. 10, Nr. 12, 3390

Benli-Hoppe, Teoman; Ozturk, Surhan Gol; Ozturk, Ozgur; Berger, Simone; Wagner, Ernst und Yazdi, Mina (2021): Transferrin Receptor Targeted Polyplexes Completely Comprised of Sequence-Defined Components. In: Macromolecular Rapid Communications, Bd. 43, Nr. 12, 2100602

Berger, Simone; Levacic, Ana Krhac; Hörterer, Elisa; Wilk, Ulrich; Benli-Hoppe, Teoman; Wang, Yanfang; Öztürk, Özgür; Luo, Jie und Wagner, Ernst (2021): Optimizing pDNA Lipo-polyplexes: A Balancing Act between Stability and Cargo Release. In: Biomacromolecules, Bd. 22, Nr. 3: S. 1282-1296

Kamenac, Andrej; Schilberth, Felix L.; Wagner, Ernst; Wixforth, Achim; Lächelt, Ulrich und Westerhausen, Christoph (2021): Transient Permeabilization of Living Cells: Combining Shear Flow and Acoustofluidic Trapping for the Facilitated Uptake of Molecules. In: Processes, Bd. 9, Nr. 6, 913

Krhač Levačić, Ana; Berger, Simone; Mueller, Judith; Wegner, Andrea; Lächelt, Ulrich; Dohmen, Christian; Rudolph, Carsten und Wagner, Ernst (2021): Dynamic mRNA polyplexes benefit from bioreducible cleavage sites for in vitro and in vivo transfer. In: Journal of Controlled Release, Bd. 339: S. 27-40

Loy, Dominik M.; Krzyszton, Rafal; Lächelt, Ulrich; Rädler, Joachim O. und Wagner, Ernst (2021): Controlling Nanoparticle Formulation: A Low-Budget Prototype for the Automation of a Microfluidic Platform. In: Processes, Bd. 9, Nr. 1, 129

Luo, Jie; Schmaus, Johannes; Cui, Mochen; Hörterer, Elisa; Wilk, Ulrich; Höhn, Miriam; Daether, Maike; Berger, Simone; Benli-Hoppe, Teoman; Peng, Lun und Wagner, Ernst (2021): Hyaluronate siRNA nanoparticles with positive charge display rapid attachment to tumor endothelium and penetration into tumors. In: Journal of Controlled Release, Bd. 329: S. 919-933

Schirnding, Constantin von; Giopanou, Ioanna; Hermawan, Adam; Wehl, Lisa; Ntaliarda, Giannoula; Illes, Bernhard; Datz, Stefan; Geisslinger, Franz; Bartel, Karin; Sommer, Ann-Katrin; Lianou, Marina; Weiss, Veronika; Feckl, Johann; Vollmar, Angelika M.; Brauchle, Christoph; Stathopoulos, Georgios T.; Wagner, Ernst; Roidl, Andreas; Bein, Thomas und Engelke, Hanna (2021): Synergistic Combination of Calcium and Citrate in Mesoporous Nanoparticles Targets Pleural Tumors. In: Chem, Bd. 7, Nr. 2: S. 480-494

Spellerberg, Rebekka; Benli-Hoppe, Teoman; Kitzberger, Carolin; Berger, Simone; Schmohl, Kathrin A.; Schwenk, Nathalie; Yen, Hsi-Yu; Zach, Christian; Schilling, Franz; Weber, Wolfgang A.; Kalin, Roland E.; Glass, Rainer; Nelson, Peter J.; Wagner, Ernst und Spitzweg, Christine (2021): Selective sodium iodide symporter (NIS) gene therapy of glioblastoma mediated by EGFR-targeted lipopolyplexes. In: Molecular Therapy-Oncolytics, Bd. 23: S. 432-446

Tutter, Mariella; Schug, Christina; Schmohl, Kathrin A.; Urnauer, Sarah; Kitzberger, Carolin; Schwenk, Nathalie; Petrini, Matteo; Zach, Christian; Ziegler, Sibylle; Bartenstein, Peter; Weber, Wolfgang A.; Multhoff, Gabriele; Wagner, Ernst; Lindner, Lars H.; Nelson, Peter J. und Spitzweg, Christine (2021): Regional Hyperthermia Enhances Mesenchymal Stem Cell Recruitment to Tumor Stroma: Implications for Mesenchymal Stem Cell-Based Tumor Therapy. In: Molecular Therapy, Bd. 29, Nr. 2: S. 788-803

2020

Wang, Yanfang und Wagner, Ernst (2020): Non-Viral Targeted Nucleic Acid Delivery: Apply Sequences for Optimization. In: Pharmaceutics, Bd. 12, Nr. 9, 888

Zhang, Peng; Zhang, Yu; Ding, Xiaoya; Shen, Wei; Li, Mingqian; Wagner, Ernst; Xiao, Chunsheng und Chen, Xuesi (2020): A Multistage Cooperative Nanoplatform Enables Intracellular Co-Delivery of Proteins and Chemotherapeutics for Cancer Therapy. In: Advanced Materials, Bd. 32, Nr. 46, 2000013

Wang, Yanfang; Luo, Jie; Truebenbach, Ines; Reinhard, Soeren; Klein, Philipp Michael; Hoehn, Miriam; Kern, Sarah; Morys, Stephan; Loy, Dominik M.; Wagner, Ernst und Zhang, Wei (2020): Double Click-Functionalized siRNA Polyplexes for Gene Silencing in Epidermal Growth Factor Receptor-Positive Tumor Cells. In: ACS Biomaterials Science & Engineering, Bd. 6, Nr. 2: S. 1074-1089

Luo, Jie; Wagner, Ernst und Wang, Yanfang (2020): Artificial peptides for antitumoral siRNA delivery. In: Journal of Materials Chemistry B, Bd. 8, Nr. 10: S. 2020-2031

Haddick, Lisa; Zhang, Wei; Reinhard, Soeren; Moeller, Karin; Engelke, Hanna; Wagner, Ernst und Bein, Thomas (2020): Particle-Size-Dependent Delivery of Antitumoral miRNA Using Targeted Mesoporous Silica Nanoparticles. In: Pharmaceutics, Bd. 12, Nr. 6, 505

Hager, Simone; Fittler, Frederic Julien; Wagner, Ernst und Bros, Matthias (2020): Nucleic Acid-Based Approaches for Tumor Therapy. In: Cells, Bd. 9, Nr. 9, 2061

Hirschle, Patrick; Hirschle, Christian; Böll, Konstantin; Döblinger, Markus; Höhn, Miriam; Tuffnell, Joshua M.; Ashling, Christopher W.; Keen, David A.; Bennett, Thomas D.; Rädler, Joachim O.; Wagner, Ernst; Peller, Michael ORCID logoORCID: https://orcid.org/0000-0002-9333-2156; Laechelt, Ulrich und Wuttke, Stefan ORCID logoORCID: https://orcid.org/0000-0002-6344-5782 (2020): Tuning the Morphological Appearance of Iron(III) Fumarate: Impact on Material Characteristics and Biocompatibility. In: Chemistry of Materials, Bd. 32, Nr. 6: S. 2253-2263

Ritt, Nicolas; Berger, Simone; Wagner, Ernst und Zentel, Rudolf (2020): Versatile, Multifunctional Block Copolymers for the Self-Assembly of Well-Defined, Nontoxic pDNA Polyplexes. In: ACS Applied Polymer Materials, Bd. 2, Nr. 12: S. 5469-5481

Kuhn, Jasmin; Lin, Yi; Levacic, Ana Krhac; Al Danaf, Nader; Peng, Lun; Hoehn, Miriam; Lamb, Don C.; Wagner, Ernst und Laechelt, Ulrich (2020): Delivery of Cas9/sgRNA Ribonucleoprotein Complexes via Hydroxystearyl Oligoamino Amides. In: Bioconjugate Chemistry, Bd. 31, Nr. 3: S. 729-742

Tutter, Mariella; Schug, Christina; Schmohl, Kathrin A.; Urnauer, Sarah; Schwenk, Nathalie; Petrini, Matteo; Lokerse, Wouter J. M.; Zach, Christian; Ziegler, Sibylle; Bartenstein, Peter; Weber, Wolfgang A.; Wagner, Ernst; Lindner, Lars H.; Nelson, Peter J. und Spitzweg, Christine (2020): Effective control of tumor growth through spatial and temporal control of theranostic sodium iodide symporter (NIS) gene expression using a heat-inducible gene promoter in engineered mesenchymal stem cells. In: Theranostics, Bd. 10, Nr. 10: S. 4490-4506

2019

Ljepoja, Bojan; Schreiber, Christoph; Gegenfurtner, Florian A.; Garcia-Roman, Jonathan; Köhler, Bianca; Zahler, Stefan; Rädler, Joachim O.; Wagner, Ernst und Roidl, Andreas (2019): Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A.
In: PLOS One 14(11), e0224314 [PDF, 2MB]

Steinborn, Benjamin; Hirschle, Patrick; Höhn, Miriam; Bauer, Tobias; Barz, Matthias; Wuttke, Stefan; Wagner, Ernst und Lächelt, Ulrich (2019): Core‐Shell Functionalized Zirconium‐Pemetrexed Coordination Nanoparticles as Carriers with a High Drug Content. In: Advanced Therapeutics, Bd. 2, Nr. 11 [PDF, 7MB]

Kuhn, Jasmin; Klein, Philipp M.; Danaf, Nader al; Nordin, Joel Z.; Reinhard, Sören; Loy, Dominik M.; Höhn, Miriam; Andaloussi, Samir el; Lamb, Don C.; Wagner, Ernst; Aoki, Yoshitsugu; Lehto, Taavi und Lächelt, Ulrich (2019): Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles. In: Advanced Functional Materials, Bd. 29, Nr. 48, 1906432 [PDF, 1MB]

Schug, Christina; Kitzberger, Carolin; Sievert, Wolfgang; Spellerberg, Rebekka; Tutter, Mariella; Schmohl, Kathrin A.; Eberlein, Bernadette; Biedermann, Tilo; Steiger, Katja; Zach, Christian; Schwaiger, Markus; Multhoff, Gabriele; Wagner, Ernst; Nelson, Peter J. und Spitzweg, Christine (2019): Radiation-Induced Amplification of TGFB1-Induced Mesenchymal Stem Cell-Mediated Sodium Iodide Symporter (NIS) Gene I-131 Therapy. In: Clinical Cancer Research, Bd. 25, Nr. 19: S. 5997-6008

Mastrella, Giorgia; Hou, Mengzhuo; Li, Min; Stöcklein, Veit M.; Zdouc, Nina; Vomar, Marie N. M.; Miletic, Hrvoje; Reinhard, Soeren; Herold-Mende, Christel C.; Kleber, Susanne; Eisenhut, Katharina; Gargiulo, Gaetano; Synowitz, Michael; Vescovi, Angelo L.; Harter, Patrick N.; Penninger, Josef M.; Wagner, Ernst; Mittelbronn, Michel; Bjerkvig, Rolf; Hambardzumyan, Dolores; Schueller, Ulrich; Tonn, Jörg-Christian; Radke, Josefine; Glass, Rainer und Kaelin, Roland E. (2019): Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma. In: Cancer Research, Bd. 79, Nr. 9: S. 2298-2313

Urnauer, Sarah; Schmohl, Kathrin A.; Tutter, Mariella; Schug, Christina; Schwenk, Nathalie; Morys, Stephan; Ziegler, Sibylle; Bartenstein, Peter; Clevert, Dirk-Andre; Wagner, Ernst und Spitzweg, Christine (2019): Dual-targeted NIS polyplexes-a theranostic strategy toward tumors with heterogeneous receptor expression. In: Gene Therapy, Bd. 26, Nr. 3-4: S. 93-108

Schug, Christina; Urnauer, Sarah; Jaeckel, Carsten; Schmohl, Kathrin A.; Tutter, Mariella; Steiger, Katja; Schwenk, Nathalie; Schwaiger, Markus; Wagner, Ernst; Nelson, Peter J. und Spitzweg, Christine (2019): TGFB1-driven mesenchymal stem cell-mediated NIS gene transfer. In: Endocrine-Related Cancer, Bd. 26, Nr. 1: S. 89-101

Zimpel, Andreas; Al Danaf, Nader; Steinborn, Benjamin; Kuhn, Jasmin; Hoehn, Miriam; Bauer, Tobias; Hirschle, Patrick; Schrimpf, Waldemar; Engelke, Hanna; Wagner, Ernst; Barz, Matthias; Lamb, Don C.; Laechelt, Ulrich und Wuttke, Stefan (2019): Coordinative Binding of Polymers to Metal-Organic Framework Nanoparticles for Control of Interactions at the Biointerface. In: ACS Nano, Bd. 13, Nr. 4: S. 3884-3895

Truebenbach, Ines; Zhang, Wei; Wang, Yanfang; Kern, Sarah; Hoehn, Miriam; Reinhard, Soeren; Gorges, Jan; Kazmaier, Uli und Wagner, Ernst (2019): Co-delivery of pretubulysin and siEG5 to EGFR overexpressing carcinoma cells. In: International Journal of Pharmaceutics, Bd. 569, 118570

Peng, Lun und Wagner, Ernst (2019): Polymeric Carriers for Nucleic Acid Delivery: Current Designs and Future Directions. In: Biomacromolecules, Bd. 20, Nr. 10: S. 3613-3626

Schnitzler, Lukas G.; Junger, Stefanie; Loy, Dominik M.; Wagner, Ernst; Wixforth, Achim; Hoerner, Andreas; Laechelt, Ulrich und Westerhausen, Christoph (2019): Size tunable nanoparticle formation employing droplet fusion by acoustic streaming applied to polyplexes. In: Journal of Physics D-Applied Physics, Bd. 52, Nr. 24, 244002

Luo, Jie; Hoehn, Miriam; Reinhard, Soeren; Loy, Dominik M.; Klein, Philipp Michael und Wagner, Ernst (2019): IL4-Receptor-Targeted Dual Antitumoral Apoptotic Peptide-siRNA Conjugate Lipoplexes. In: Advanced Functional Materials, Bd. 29, Nr. 25, 1900697

Truebenbach, Ines; Kern, Sarah; Loy, Dominik M.; Hoehn, Miriam; Gorges, Jan; Kazmaier, Uli und Wagner, Ernst (2019): Combination Chemotherapy of L1210 Tumors in Mice with Pretubulysin and Methotrexate Lipo-Oligomer Nanoparticles. In: Molecular Pharmaceutics, Bd. 16, Nr. 6: S. 2405-2417

Kern, Sarah; Truebenbach, Ines; Hoehn, Miriam; Gorges, Jan; Kazmaier, Uli; Zahler, Stefan; Vollmar, Angelika M. und Wagner, Ernst (2019): Combined antitumoral effects of pretubulysin and methotrexate. In: Pharmacology Research & Perspectives, Bd. 7, Nr. 1, UNSP e00460

Sommer, Ann-Katrin; Falcenberg, Mathias; Ljepoja, Bojan; Fröhlich, Thomas; Arnold, Georg J.; Wagner, Ernst und Roidl, Andreas (2019): Downregulation of GRK5 hampers the migration of breast cancer cells. In: Scientific Reports, Bd. 9, 15548 [PDF, 5MB]

Pfitzer, Lisa; Moser, Christina; Gegenfurtner, Florian; Arner, Anja; Foerster, Florian; Atzberger, Carina; Zisis, Themistoklis; Kubisch-Dohmen, Rebekka; Busse, Johanna; Smith, Rebecca; Timinszky, Gyula; Kalinina, Olga V.; Müller, Rolf; Wagner, Ernst; Vollmar, Angelika M. und Zahler, Stefan (2019): Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy. In: Cell Death & Disease, Bd. 10, UNSP 302

Ljepoja, Bojan; Garcia-Roman, Jonathan; Sommer, Ann-Katrin; Wagner, Ernst und Roidl, Andreas (2019): MiRNA-27a sensitizes breast cancer cells to treatment with Selective Estrogen Receptor Modulators. In: Breast, Bd. 43: S. 31-38

2018

Hirschberger, Kristin; Jarzebinska, Anita; Kessel, Eva; Kretzschmann, Verena; Aneja, Manish K.; Dohmen, Christian; Herrmann-Janson, Annika; Wagner, Ernst; Plank, Christian und Rudolph, Carsten (2018): Exploring Cytotoxic mRNAs as a Novel Class of Anti-cancer Biotherapeutics. In: Molecular Therapy-Methods & Clinical Development, Bd. 8: S. 141-151 [PDF, 1MB]

Urbiola, Koldo; Blanco-Fernandez, Laura; Ogris, Manfred; Rodl, Wolfgang; Wagner, Ernst und Ilarduya, Conchita Tros de (2018): Novel PAMAM-PEG-Peptide Conjugates for siRNA Delivery Targeted to the Transferrin and Epidermal Growth Factor Receptors. In: Journal of Personalized Medicine, Bd. 8, Nr. 1 [PDF, 1MB]

Qian, Min; Du, Yilin; Wang, Shanshan; Li, Chengyi; Jiang, Huiling; Shi, Wei; Chen, Jian; Wang, Yi; Wagner, Ernst und Huang, Rongqin (2018): Highly Crystalline Multicolor Carbon Nanodots for Dual-Modal Imaging-Guided Photothermal Therapy of Glioma. In: ACS Applied Materials & Interfaces, Bd. 10, Nr. 4: S. 4031-4040

Reinhard, Sören; Wang, Yanfang; Dengler, Sebastian und Wagner, Ernst (2018): Precise Enzymatic Cleavage Sites for Improved Bioactivity of siRNA Lipo-Polyplexes. In: Bioconjugate Chemistry, Bd. 29, Nr. 11: S. 3649-3657

Deglmann, Claus J.; Blazkow-Schmalzbauer, Katarzyna; Moorkamp, Sarah; Wallmichrath, Jens; Giunta, Riccardo E.; Rogach, Andrey L.; Wagner, Ernst; Baumeister, Rüdiger G. und Ogris, Manfred (2018): In vivo tracking of adipose tissue grafts with cadmium-tel-luride quantum dots. In: Archives of Plastic Surgery-Aps, Bd. 45, Nr. 2: S. 111-117 [PDF, 1MB]

Morys, Stephan; Urnauer, Sarah; Spitzweg, Christine und Wagner, Ernst (2018): EGFR Targeting and Shielding of pDNA Lipopolyplexes via Bivalent Attachment of a Sequence-Defined PEG Agent. In: Macromolecular Bioscience, Bd. 18, Nr. 1, 1700203

Schug, Christina; Sievert, Wolfgang; Urnauer, Sarah; Müller, Andrea M.; Schmohl, Kathrin A.; Wechselberger, Alexandra; Schwenk, Nathalie; Lauber, Kirsten; Schwaiger, Markus; Multhoff, Gabriele; Wagner, Ernst; Nelson, Peter J. und Spitzweg, Christine (2018): External Beam Radiation Therapy Enhances Mesenchymal Stem Cell-Mediated Sodium-Iodide Symporter Gene Delivery. In: Human Gene Therapy, Bd. 29, Nr. 11: S. 1287-1300

Klein, Philipp Michael; Klinker, Kristina; Zhang, Wei; Kern, Sarah; Kessel, Eva; Wagner, Ernst und Barz, Matthias (2018): Efficient Shielding of Polyplexes Using Heterotelechelic Polysarcosines. In: Polymers, Bd. 10, Nr. 6, 689 [PDF, 2MB]

Ljepoja, Bojan; Garcia-Roman, Jonathan; Sommer, Ann-Katrin; Frohlich, Thomas; Arnold, Georg J.; Wagner, Ernst und Roidl, Andreas (2018): A proteomic analysis of an in vitro knock-out of miR-200c. In: Scientific Reports, Bd. 8, 6927 [PDF, 3MB]

Klein, Philipp Michael; Kern, Sarah; Lee, Dian-Jang; Schmaus, Johannes; Hoehn, Miriam; Gorges, Jan; Kazmaier, Uli und Wagner, Ernst (2018): Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo. In: Biomaterials, Bd. 178: S. 630-642

Sommer, Ann-Katrin; Hermawan, Adam; Ljepoja, Bojan; Fröhlich, Thomas; Arnold, Georg J.; Wagner, Ernst und Roidl, Andreas (2018): A proteomic analysis of chemoresistance development via sequential treatment with doxorubicin reveals novel players in MCF-7 breast cancer cells. In: International Journal of Molecular Medicine, Bd. 42, Nr. 4: S. 1987-1997

Hager, Simone und Wagner, Ernst (2018): Bioresponsive polyplexes - chemically programmed for nucleic acid delivery. In: Expert Opinion on Drug Delivery, Bd. 15, Nr. 11: S. 1067-1083

Steinborn, Benjamin; Truebenbach, Ines; Morys, Stephan; Laechelt, Ulrich; Wagner, Ernst und Zhang, Wei (2018): Epidermal growth factor receptor targeted methotrexate and small interfering RNA co-delivery. In: Journal of Gene Medicine, Bd. 20, Nr. 7-8, e3041

2017

Tippelt, Rudolf (2017): Soziokulturelle Milieus. In: Wagner, Ernst; Wenrich, Rainer und Ratzel, Ann-Jasmin (Hrsg.): Diversity im Kunstunterricht ; Modelle inter- und transkultureller Vermittlungspraxis. München: kopaed. S. 210-218

Kiel, Ewald (2017): Der Umgang mit Kultur im Unterricht. In: Wagner, Ernst; Wenrich, Rainer und Ratzel, Ann-Jasmin (Hrsg.): Diversity im Kunstunterricht ; Modelle inter- und transkultureller Vermittlungspraxis. München: kopaed. S. 240-248

Urnauer, Sarah; Klutz, Kathrin; Grünwald, Geoffrey K.; Morys, Stephan; Schwenk, Nathalie; Zach, Christian; Gildehaus, Franz-Josef; Rödl, Wolfgang; Ogris, Manfred; Wagner, Ernst und Spitzweg, Christine (2017): Systemic tumor-targeted sodium iodide symporter (NIS) gene therapy of hepatocellular carcinoma mediated by B6 peptide polyplexes. In: Journal of Gene Medicine, Bd. 19, Nr. 5, e2957

Urnauer, Sarah; Müller, Andrea M.; Schug, Christina; Schmohl, Kathrin A.; Tutter, Mariella; Schwenk, Nathalie; Rödl, Wolfgang; Morys, Stephan; Ingrisch, Michäl; Bertram, Jens; Bartenstein, Peter; Clevert, Dirk-André; Wagner, Ernst und Spitzweg, Christine (2017): EGFR-targeted nonviral NIS gene transfer for bioimaging and therapy of disseminated colon cancer metastases. In: Oncotarget, Bd. 8, Nr. 54: S. 92195-92208

Schmohl, Kathrin A.; Dolp, Patrick; Schug, Christina; Knoop, Kerstin; Klutz, Kathrin; Schwenk, Nathalie; Bartenstein, Peter; Nelson, Peter J.; Ogris, Manfred; Wagner, Ernst und Spitzweg, Christine (2017): Reintroducing the Sodium-Iodide Symporter to Anaplastic Thyroid Carcinoma. In: Thyroid, Bd. 27, Nr. 12: S. 1534-1543

Morys, Stephan; Levacic, Ana Krhac; Urnauer, Sarah; Kempter, Susanne; Kern, Sarah; Rädler, Joachim O.; Spitzweg, Christine; Lächelt, Ulrich und Wagner, Ernst (2017): Influence of Defined Hydrophilic Blocks within Oligoaminoamide Copolymers: Compaction versus Shielding of pDNA Nanoparticles. In: Polymers, Bd. 9, Nr. 4, 142 [PDF, 2MB]

Schmohl, Kathrin A.; Gupta, Aayush; Grünwald, Geoffrey K.; Trajkovic-Arsic, Marija; Klutz, Kathrin; Braren, Rickmer; Schwaiger, Markus; Nelson, Peter J.; Ogris, Manfred; Wagner, Ernst; Siveke, Jens T. und Spitzweg, Christine (2017): Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the theranostic sodium iodide symporter (NIS) gene. In: Oncotarget, Bd. 8, Nr. 20: S. 33393-33404 [PDF, 5MB]

Lee, Dian-Jang; Kessel, Eva; Lehto, Taavi; Liu, Xueying; Yoshinaga, Naoto; Padari, Kart; Chen, Ying-Chen; Kempter, Susanne; Uchida, Satoshi; Rädler, Joachim O.; Pooga, Margus; Sheu, Ming-Thau; Kataoka, Kazunori und Wagner, Ernst (2017): Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia. In: Bioconjugate Chemistry, Bd. 28, Nr. 9: S. 2393-2409

Nino-Pariente, Amaya; Arminan, Ana; Reinhard, Sören; Scholz, Claudia; Wagner, Ernst und Vicent, Maria J. (2017): Design of Poly-l-Glutamate-Based Complexes for pDNA Delivery. In: Macromolecular Bioscience, Bd. 17, Nr. 10, 1700029

Nino-Pariente, Amaya; Arminan, Ana; Reinhard, Sören; Scholz, Claudia; Kos, Petra; Wagner, Ernst und Vicent, Maria J. (2017): Design of Poly-l-Glutamate-Based Complexes for pDNA Delivery (vol 10, 1700029, 2017). In: Macromolecular Bioscience, Bd. 17, Nr. 10, 1700245

Heller, Philipp; Hobernik, Dominika; Lächelt, Ulrich; Schinnerer, Meike; Weber, Benjamin; Schmidt, Manfred; Wagner, Ernst; Bros, Matthias und Barz, Matthias (2017): Combining reactive triblock copolymers with functional cross-linkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines. In: Journal of Controlled Release, Bd. 258: S. 146-160

Moghimi, S. Moein und Wagner, Ernst (2017): Nanoparticle Technology: Having Impact, but Needing Further Optimization. In: Molecular therapy, Bd. 25, Nr. 7: S. 1461-1463

Hall, Arnaldur; Lächelt, Ulrich; Bartek, Jiri; Wagner, Ernst und Moghimi, Seyed Moein (2017): Polyplex Evolution: Understanding Biology, Optimizing Performance. In: Molecular therapy, Bd. 25, Nr. 7: S. 1476-1490

Klein, Philipp M.; Reinhard, Sören; Zhang, Wei; Klinker, Kristina; Kern, Sarah; Kessel, Eva; Barz, Matthias und Wagner, Ernst (2017): Novel Poly(Sarcosine) Click Shielding Agents Improve Circulation of Redox-Sensitive siRNA Lipo-Polyplexes In Vivo. In: Molecular therapy, Bd. 25, Nr. 5: S. 144

Röder, Ruth; Helma, Jonas; Prei, Tobias; Rädler, Joachim O.; Leonhardt, Heinrich und Wagner, Ernst (2017): Intracellular Delivery of Nanobodies for Imaging of Target Proteins in Live Cells. In: Pharmaceutical Research, Bd. 34, Nr. 1: S. 161-174

Trübenbach, Ines; Gorges, Jan; Kuhn, Jasmin; Kern, Sarah; Baratti, Emanuele; Kazmaier, Uli; Wagner, Ernst und Lächelt, Ulrich (2017): Sequence-Defined Oligoamide Drug Conjugates of Pretubulysin and Methotrexate for Folate Receptor Targeted Cancer Therapy. In: Macromolecular Bioscience, Bd. 17, Nr. 10, 1600520

Levacic, Ana Krhac; Morys, Stephan; Kempter, Susanne; Lächelt, Ulrich und Wagner, Ernst (2017): Minicircle Versus Plasmid DNA Delivery by Receptor-Targeted Polyplexes. In: Human Gene therapy, Bd. 28, Nr. 10: S. 862-874

Wang, Shanshan; Li, Chengyi; Qian, Min; Jiang, Huiling; Shi, Wei; Chen, Jian; Lächelt, Ulrich; Wagner, Ernst; Lu, Weiyue; Wang, Yi und Huang, Rongqin (2017): Augmented glioma-targeted theranostics using multifunctional polymer-coated carbon nanodots. In: Biomaterials, Bd. 141: S. 29-39

Liu, Xiaowen; Zhang, Peng; Rodl, Wolfgang; Maier, Kevin; Lächelt, Ulrich und Wagner, Ernst (2017): Toward Artificial Immunotoxins: Traceless Reversible Conjugation of RNase A with Receptor Targeting and Endosomal Escape Domains. In: Molecular Pharmaceutics, Bd. 14, Nr. 5: S. 1439-1449

Zhang, Peng und Wagner, Ernst (2017): History of Polymeric Gene Delivery Systems. In: Topics in Current Chemistry, Bd. 375, Nr. 2, 26

Heissig, Philipp; Schrimpf, Waldemar; Hadwiger, Philipp; Wagner, Ernst und Lamb, Don C. (2017): Monitoring integrity and localization of modified single-stranded RNA oligonucleotides using ultrasensitive fluorescence methods.
In: PLOS One 12(3), e0173401 [PDF, 3MB]

Reinhard, Sören; Zhang, Wei und Wagner, Ernst (2017): Optimized Solid-Phase-Assisted Synthesis of Oleic Acid Containing siRNA Nanocarriers. In: ChemMedChem, Bd. 12, Nr. 17: S. 1464-1470

Zhang, Peng; Steinborn, Benjamin; Lächelt, Ulrich; Zahler, Stefan und Wagner, Ernst (2017): Lipo-Oligomer Nanoformulations for Targeted Intracellular Protein Delivery. In: Biomacromolecules, Bd. 18, Nr. 8: S. 2509-2520

Wang, Shanshan; Reinhard, Sören; Li, Chengyi; Qian, Min; Jiang, Huiling; Du, Yilin; Lächelt, Ulrich; Lu, Weiyue; Wagner, Ernst und Huang, Rongqin (2017): Antitumoral Cascade-Targeting Ligand for IL-6 Receptor-Mediated Gene Delivery to Glioma. In: Molecular therapy, Bd. 25, Nr. 7: S. 1556-1566

Deglmann, Claus J.; Błażków-Schmalzbauer, Katarzyna; Moorkamp, Sarah; Susha, Andrei S.; Herrler, Tanja; Giunta, Riccardo E.; Wagner, Ernst; Rogach, Andrey L.; Baumeister, Ruediger G. und Ogris, Manfred (2017): Cadmium Telluride Quantum Dots as a Fluorescence Marker for Adipose Tissue Grafts. In: Annals of Plastic Surgery, Bd. 78, Nr. 2: S. 217-222 [PDF, 586kB]

Röder, Ruth; Preiß, Tobias; Hirschle, Patrick; Steinborn, Benjamin; Zimpel, Andreas; Höhn, Miriam; Rädler, Joachim O.; Bein, Thomas; Wagner, Ernst; Wuttke, Stefan und Lächelt, Ulrich (2017): Multifunctional Nanoparticles by Coordinative Self-Assembly of His Tagged Units with Metal Organic Frameworks. In: Journal of the American Chemical Society, Bd. 139, Nr. 6: S. 2359-2368

Reinhard, Sören und Wagner, Ernst (2017): How to Tackle the Challenge of siRNA Delivery with Sequence-Defined Oligoamino Amides. In: Macromolecular Bioscience, Bd. 17, Nr. 1, 1600152

2016

Möller, Karin; Müller, Katharina; Engelke, Hanna; Bräuchle, Christoph; Wagner, Ernst und Bein, Thomas (2016): Highly efficient siRNA delivery from core – shell mesoporous silica nanoparticles with multifunctional polymer caps. In: Nanoscale, Bd. 8, Nr. 7, 4007 [PDF, 4MB]

Klein, Philipp M.; Reinhard, Sören; Lee, Dian-Jang; Müller, Katharina; Ponader, Daniela; Hartmann, Laura und Wagner, Ernst (2016): Precise redox-sensitive cleavage sites for improved bioactivity of siRNA lipopolyplexes. In: Nanoscale, Bd. 8, Nr. 42: S. 18098-18104 [PDF, 1MB]

Westerhausen, Christoph; Schnitzler, Lukas G.; Wendel, Dominik; Krzyszton, Rafal; Lächelt, Ulrich; Wagner, Ernst; Rädler, Joachim O. und Wixforth, Achim (2016): Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles. In: Micromachines, Bd. 7, Nr. 9, 150 [PDF, 4MB]

Schreiber, Christoph; Segerer, Felix J.; Wagner, Ernst; Roidl, Andreas und Rädler, Joachim O. (2016): Ring-Shaped Microlanes and Chemical Barriers as a Platform for Probing Single-Cell Migration. In: Scientific Reports, Bd. 6, 26858 [PDF, 811kB]

Heissig, Philipp; Klein, Philipp M.; Hadwiger, Philipp und Wagner, Ernst (2016): DNA as Tunable Adaptor for siRNA Polyplex Stabilization and Functionalization. In: Molecular Therapy - Nucleic Acids, Bd. 5, e288 [PDF, 1MB]

Urnauer, Sarah; Morys, Stephan; Levacic, Ana Krhac; Müller, Andrea M.; Schug, Christina; Schmohl, Kathrin A.; Schwenk, Nathalie; Zach, Christian; Carlsen, Janette; Bartenstein, Peter; Wagner, Ernst und Spitzweg, Christine (2016): Sequence-defined cMET/HGFR-targeted Polymers as Gene Delivery Vehicles for the Theranostic Sodium Iodide Symporter (NIS) Gene. In: Molecular therapy, Bd. 24, Nr. 8: S. 1395-1404

Müller, Andrea M.; Schmohl, Kathrin A.; Knoop, Kerstin; Schug, Christina; Urnauer, Sarah; Hagenhoff, Anna; Clevert, Dirk-André; Ingrisch, Michael; Niess, Hanno; Carlsen, Janette; Zach, Christian; Wagner, Ernst; Bartenstein, Peter; Nelson, Peter J. und Spitzweg, Christine (2016): Hypoxia-targeted I-131 therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated sodium iodide symporter gene delivery. In: Oncotarget, Bd. 7, Nr. 34: S. 54795-54810

He, Dongsheng; Müller, Katharina; Levacic, Ana Krhac; Kos, Petra; Lächelt, Ulrich und Wagner, Ernst (2016): Combinatorial Optimization of Sequence-Defined Oligo(ethanamino)amides for Folate Receptor-Targeted pDNA and siRNA Delivery. In: Bioconjugate Chemistry, Bd. 27, Nr. 3: S. 647-659

Liu, Xiaowen; Zhang, Peng; He, Dongsheng; Rödl, Wolfgang; Preiß, Tobias; Rädler, Joachim O.; Wagner, Ernst und Lächelt, Ulrich (2016): pH-Reversible Cationic RNase A Conjugates for Enhanced Cellular Delivery and Tumor Cell Killing. In: Biomacromolecules, Bd. 17, Nr. 1: S. 173-182

Zimpel, Andreas; Preiß, Tobias; Röder, Ruth; Engelke, Hanna; Ingrisch, Michael; Peller, Michael; Rädler, Joachim O.; Wagner, Ernst; Bein, Thomas; Lächelt, Ulrich und Wuttke, Stefan (2016): Imparting Functionality to MOF Nanoparticles by External Surface Selective Covalent Attachment of Polymers. In: Chemistry of Materials, Bd. 28, Nr. 10: S. 3318-3326

Jiang, Qian; Yue, Dong; Nie, Yu; Xu, Xianghui; He, Yiyan; Zhang, Shiyong; Wagner, Ernst und Gu, Zhongwei (2016): Specially-Made Lipid-Based Assemblies for Improving Transmembrane Gene Delivery: Comparison of Basic Amino Acid Residue Rich Periphery. In: Molecular Pharmaceutics, Bd. 13, Nr. 6: S. 1809-1821

Müller, Katherina; Kessel, Eva; Klein, Philipp M.; Höhn, Miriam und Wagner, Ernst (2016): Post-PEGylation of siRNA Lipo-oligoamino Amide Polyplexes Using Tetra-glutamylated Folic Acid as Ligand for Receptor-Targeted Delivery. In: Molecular Pharmaceutics, Bd. 13, Nr. 7: S. 2332-2345

Zhang, Wei; Müller, Katharina; Kessel, Eva; Reinhard, Sören; He, Dongsheng; Klein, Philipp M.; Höhn, Miriam; Rödl, Wolfgang; Kempter, Susanne und Wagner, Ernst (2016): Targeted siRNA Delivery Using a Lipo-Oligoaminoamide Nanocore with an Influenza Peptide and Transferrin Shell. In: Advanced Healthcare Materials, Bd. 5, Nr. 12: S. 1493-1504

Lee, Dian-Jang; Kessel, Eva; Edinger, Daniel; He, Dongsheng; Klein, Philipp M.; Voith von Voithenberg, Lena; Lamb, Don C.; Lächelt, Ulrich; Lehto, Taavi und Wagner, Ernst (2016): Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand. In: Biomaterials, Bd. 77: S. 98-110

Lee, Dian-Jang; He, Dongsheng; Kessel, Eva; Padari, Kärt; Kempter, Susanne; Lächelt, Ulrich; Rädler, Joachim O.; Pooga, Margus und Wagner, Ernst (2016): Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes. In: Journal of Controlled Release, Bd. 244: S. 280-291

Sommer, Ann-Katrin; Hermawan, Adam; Mickler, Frauke Martina; Ljepoja, Bojan; Knyazev, Pjotr; Bräuchle, Christoph; Ullrich, Axel; Wagner, Ernst und Roidl, Andreas (2016): Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases. In: Oncotarget, Bd. 7, Nr. 31: S. 50461-50476

Müller, Katharina; Klein, Philipp M.; Heissig, Philipp; Roidl, Andreas und Wagner, Ernst (2016): EGF receptor targeted lipo-oligocation polyplexes for antitumoral siRNA and miRNA delivery. In: Nanotechnology, Bd. 27, Nr. 46, 464001

Lächelt, Ulrich; Levacic, Ana Krhac; Wendel, Dominik und Wagner, Ernst (2016): Nonviral Gene Transfer by Sequence-Defined Proton-Sponges with Combined Nucleic Acid Binding and Endosomal Buffering: Balancing Basicities. In: Molecular therapy, Bd. 24: S195-S195

Hermawan, Adam; Wagner, Ernst und Roidl, Andreas (2016): Consecutive salinomycin treatment reduces doxorubicin resistance of breast tumor cells by diminishing drug efflux pump expression and activity. In: Oncology Reports, Bd. 35, Nr. 3: S. 1732-1740

2015

Niedermayer, Stefan; Weiss, Veronika; Herrmann, Annika; Schmidt, Alexandra; Datz, Stefan; Müller, Katharina; Wagner, Ernst; Bein, Thomas und Bräuchle, Christoph (2015): Multifunctional polymer-capped mesoporous silica nanoparticles for pH-responsive targeted drug delivery. In: Nanoscale, Bd. 7, Nr. 17: S. 7953-7964 [PDF, 2MB]

2014

Kopp, Florian; Hermawan, Adam; Oak, Prajakta Shirish; Herrmann, Annika; Wagner, Ernst und Roidl, Andreas (2014): Salinomycin treatment reduces metastatic tumor burden by hampering cancer cell migration. In: Molecular Cancer 13:16 [PDF, 1MB]

Kopp, Florian; Hermawan, Adam; Oak, Prajakta Shirish; Ulaganathan, Vijay Kumar; Herrmann, Annika; Elnikhely, Nefertiti; Thakur, Chitra; Xiao, Zhiguang; Knyazev, Pjotr; Ataseven, Beyhan; Savai, Rajkumar; Wagner, Ernst und Roidl, Andreas (2014): Sequential Salinomycin Treatment Results in Resistance Formation through Clonal Selection of Epithelial-Like Tumor Cells. In: Translational Oncology, Bd. 7, Nr. 6: S. 702-711 [PDF, 1MB]

Menhofer, Magdalena H.; Kubisch, Rebekka; Schreiner, Laura; Zorn, Matthias; Foerster, Florian; Mueller, Rolf; Rädler, Joachim O.; Wagner, Ernst; Vollmar, Angelika M. und Zahler, Stefan (2014): The Actin Targeting Compound Chondramide Inhibits Breast Cancer Metastasis via Reduction of Cellular Contractility.
In: PLOS ONE 9(11), e112542 [PDF, 1MB]

Kos, Petra; Lächelt, Ulrich; Herrmann, Annika; Mickler, Frauke M.; Krhač Levačić, Ana; Morys, Stephan; Bräuchle, Christoph und Wagner, Ernst (2014): Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer. In: Nanoscale, Bd. 7, Nr. 12: S. 5350-5362 [PDF, 0B]

2013

Wagner, Ernst (10. Mai 2013): Biomaterials in RNAi therapeutics: quo vadis? In: Biomaterials Science, Bd. 1, Nr. 8: S. 804-809 [PDF, 1MB]

Haase, Rudolf; Magnusson, Terese; Su, Baowei; Kopp, Florian; Wagner, Ernst; Lipps, Hans; Baiker, Armin und Ogris, Manfred (2013): Generation of a tumor- and tissue-specific episomal non-viral vector system. In: BMC Biotechnology 13:49 [PDF, 485kB]

Marfels, Christian; Hoehn, Miriam; Wagner, Ernst und Guenther, Michael (2013): Characterization of in vivo chemoresistant human hepatocellular carcinoma cells with transendothelial differentiation capacities. In: BMC Cancer 13:176 [PDF, 3MB]

2012

Maier, Kevin; Martin, Irene und Wagner, Ernst (9. November 2012): Sequence Defined Disulfide-Linked Shuttle for Strongly Enhanced Intracellular Protein Delivery. In: Molecular pharmaceutics, Bd. 9, Nr. 12: S. 3560-3568 [PDF, 467kB]

Maier, Kevin und Wagner, Ernst (22. Mai 2012): Acid-Labile Traceless Click Linker for Protein Transduction. In: Journal of the American Chemical Society, Bd. 134, Nr. 24: S. 10169-10173 [PDF, 310kB]

Schaffert, David; Troiber, Christina und Wagner, Ernst (2. Mai 2012): New Sequence-Defined Polyaminoamides with Tailored Endosomolytic Properties for Plasmid DNA Delivery. In: Bioconjugate chemistry, Bd. 23, Nr. 6: S. 1157-1165 [PDF, 440kB]

Dohmen, Christian; Edinger, Daniel; Fröhlich, Thomas; Schreiner, Laura; Lächelt, Ulrich; Troiber, Christina; Rädler, Joachim O.; Hadwiger, Philipp; Vornlocher, Hans-Peter und Wagner, Ernst (2012): Nanosized Multifunctional Polyplexes for Receptor-Mediated SiRNA Delivery. In: ACS Nano, Bd. 6, Nr. 6: S. 5198-5208 [PDF, 660kB]

Terziyska, Nadia; Castro Alves, Catarina; Groiss, Volker; Schneider, Katja; Farkasova, Katarina; Ogris, Manfred; Wagner, Ernst; Ehrhardt, Harald; Brentjens, Renier J.; zur Stadt, Udo; Horstmann, Martin; Quintanilla-Martinez, Leticia und Jeremias, Irmela (2012): In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice.
In: PLOS ONE 7(12), e52798 [PDF, 1MB]

Kopp, Florian; Oak, Prajakta S.; Wagner, Ernst und Roidl, Andreas (2012): miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression.
In: PLOS ONE 7(11), e50469 [PDF, 700kB]

Martin, Irene; Dohmen, Christian; Mas-Moruno, Carlos; Troiber, Christina; Kos, Petra; Schaffert, David; Lächelt, Ulrich; Teixido, Meritxell; Günther, Michael; Kessler, Horst; Giralt, Ernest und Wagner, Ernst (2012): Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery. In: Organic and Biomolecular Chemistry, Bd. 10, Nr. 16: S. 3258-3268 [PDF, 1MB]

2011

Wagner, Ernst (22. Dezember 2011): Polymers for siRNA Delivery. Inspired by Viruses to be Targeted, Dynamic, and Precise. In: Accounts of chemical research, Bd. 45, Nr. 7: S. 1005-1013 [PDF, 462kB]

Troiber, Christina und Wagner, Ernst (2011): Nucleic Acid Carriers Based on Precise Polymer Conjugates. In: Bioconjugate chemistry, Bd. 22, Nr. 9: S. 1737-1752 [PDF, 1MB]

Yu, Haijun; Nie, Yu; Dohmen, Christian; Li, Yunqiu und Wagner, Ernst (2011): Epidermal Growth Factor–PEG Functionalized PAMAM-Pentaethylenehexamine Dendron for Targeted Gene Delivery Produced by Click Chemistry. In: iomacromolecules, Bd. 12, Nr. 6: S. 2039-2047 [PDF, 1MB]

Schaffert, David; Badgujar, Naresh und Wagner, Ernst (2011): Novel Fmoc-Polyamino Acids for Solid-Phase Synthesis of Defined Polyamidoamines. In: Organic letters, Bd. 13, Nr. 7: S. 1586-1589 [PDF, 738kB]

Dussmann, Philipp; Pagel, Judith I.; Vogel, Sabina; Magnusson, Terese; Zimmermann, Rene; Wagner, Ernst; Schaper, Wolfgang; Ogris, Manfred und Deindl, Elisabeth (2011): Live in vivo imaging of Egr-1 promoter activity during neonatal development, liver regeneration and wound healing. In: BMC Developmental Biology 11:28 [PDF, 2MB]

2008

Zintchenko, Arkadi; Philipp, Alexander; Dehshahri, Ali und Wagner, Ernst (2008): Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity. In: Bioconjugate chemistry, Bd. 19, Nr. 7: S. 1448-1455 [PDF, 217kB]

Meyer, Martin; Philipp, Alexander; Oskuee, Reza; Schmidt, Claudia und Wagner, Ernst (2008): Breathing Life into Polycations. Functionalization with pH-Responsive Endosomolytic Peptides and Polyethylene Glycol Enables siRNA Delivery. In: Journal of the American Chemical Society, Bd. 130, Nr. 11: S. 3272-3273 [PDF, 135kB]

2006

Shir, Alexei; Ogris, Manfred; Wagner, Ernst und Levitzki, Alexander (2006): EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice.
In: PLOS Medicine 3(1), e6 , S. 125-135 [PDF, 868kB]

1994

Curiel, Tyler J.; Cook, Deborah R.; Bogedain, Christoph; Jilg, Wolfgang; Harrison, Gail S.; Cotten, Matt; Curiel, David T. und Wagner, Ernst (1994): Efficient Foreign Gene Expression in Epstein-Barr Virus-Transformed Human B-Cells. In: Virology, Bd. 198, Nr. 2: S. 577-585 [PDF, 561kB]

Noe, Christian R.; Knollmüller, Max; Miculka, Christian; Dungler, Karin; Wagner, Ernst und Ettmayer, Peter (1994): Chirale Lactole, XI. Eine Methode zur Bestimmung der Absolutkonfiguration chiraler Alkanole. In: Chemische Berichte, Bd. 127, Nr. 5: S. 887-892 [PDF, 1MB]

Zatloukal, Kurt; Cotten, Matt; Berger, Manfred; Schmidt, Walter; Wagner, Ernst und Birnstiel, Max L. (1994): In vivo production of human factor VII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery. In: Proceedings of the National Academy of Science of the U S A, Bd. 91, Nr. 11: S. 5148-5152 [PDF, 1MB]

Plank, Christian; Oberhauser, Berndt; Mechtler, Karl; Koch, Christian und Wagner, Ernst (1994): The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. In: Journal of Biological Chemistry, Bd. 269: S. 12918-12924 [PDF, 2MB]

Cheng, Qi; Cant, Charles; Moll, Thomas; Hofer-Warbinek, Renate; Wagner, Ernst; Birnstiel, Max L.; Bach, Fritz H. und Martin, Rainer de (1994): NK-kappa B subunit-specific regulation of the I kappa B alpha promoter. In: Journal of Biological Chemistry, Bd. 269: S. 13551-13557 [PDF, 2MB]

Wagner, Ernst; Cotten, Matt; Plank, Christian; Mechtler, Karl; Zatloukal, Kurt und Birnstiel, Max L. (1994): Receptor-mediated gene delivery into mammalian cells. In: Spier, R. E. (Hrsg.): Animal cell technology: Products of today, prospects for tomorrow. Oxford: Butterworth Heinemann. S. 30-34 [PDF, 1MB]

Wagner, Ernst; Curiel, David T. und Cotten, Matt (1994): Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis. In: Advanced Drug Delivery Reviews, Bd. 14, Nr. 1: S. 113-135 [PDF, 1MB]

Wagner, Ernst; Buschle, M.; Cotten, Matt; Plank, Christian; Zauner, W. und Birnstiel, Max L. (1994): Synthetic virus-like gene delivery systems. 21. International Symposium on controlled release of bioactive materials, Nizza, 27-30 Juni 1994. Guy, Richard H. (Hrsg.): In: Proceedings of the 21. International Symposium on controlled release of bioactive materials, Deerfield, Ill.: Controlled Release Society. S. 3-4 [PDF, 432kB]

Thurnher, Martin; Wagner, Ernst; Clausen, Henrik; Mechtler, Karl; Rusconi, Sandro; Dinter, André; Birnstiel, Max L.; Berger, Eric G. und Cotten, Matt (1994): Carbohydrate receptor-mediated gene transfer to human T leukaemic cells. In: Glycobiology, Bd. 4: S. 429-435 [PDF, 3MB]

Cotten, Matt; Baker, A.; Saltik, Mediyha; Wagner, Ernst und Buschle, M. (1994): Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary cells in the presence of adenovirus. In: Gene Therapy, Bd. 1: S. 239-246 [PDF, 6MB]

Zelphati, Olivier; Wagner, Ernst und Leserman, Lee (1994): Synthesis and anti-HIV activity of thiocholesteryl-coupled phosphodiester antisense oligonucleotides incorporated into immunoliposomes. In: Antiviral Research, Bd. 25, Nr. 1: S. 13-25 [PDF, 814kB]

Maass, Gerd; Zatloukal, Kurt; Schmidt, Walter; Berger, M.; Cotten, Matt; Wagner, Ernst; Birnstiel, Max L. und Buschle, M. (1994): The generation of tumor vaccines by adenovirus-enhanced transfection of cytokine genes into tumor cells. In: Skouteris, George G. (Hrsg.): Liver carcinogenesis. Berlin u.a.: Springer. S. 467-479 [PDF, 1MB]

Batra, R. K.; Wang-Johanning, F.; Wagner, Ernst; Garver, R. I. und Curiel, David T. (1994): Receptor-mediated gene delivery employing lectin-binding specificity. In: Gene Therapy, Bd. 1: S. 255-260 [PDF, 1MB]

Cotten, Matt; Saltik, Mediyha; Kursa, Malgorzata; Wagner, Ernst; Maass, Gerd und Birnstiel, Max L. (1994): Psoralen Treatment of Adenovirus Particles Eliminates Virus Replication and Transcription While Maintaining the Endosomolytic Activity of the Virus Capsid. In: Virology, Bd. 205, Nr. 1: S. 254-261 [PDF, 545kB]

Frank, Sasa; Krasznai, Krisztina; Durovic, Srdan; Lobentanz, Eva-Maria; Dieplinger, Hans; Wagner, Ernst; Zatloukal, Kurt; Cotten, Matt; Utermann, Gerd; Kostner, Gerd M. und Zechner, Rudolf (1994): High-Level Expression of Various Apolipoprotein (a) Isoforms by "Transferrinfection". The Role of Kringle IV Sequences in the Extracellular Association with Low-Density Lipoprotein. In: Biochemistry, Bd. 33, Nr. 40: S. 12329-12339 [PDF, 3MB]

Zatloukal, Kurt; Schneeberger, A.; Berger, M.; Koszik, F.; Schmidt, Walter; Wagner, Ernst; Cotten, Matt; Buschle, M.; Maass, Gerd; Stingl, Georg und Birnstiel, Max L. (1994): Genetic modification of cells by receptor-mediated adenovirus-augmented gene delivery. A new approach for immunotherapy of cancer. In: Verhandlungen der Deutschen Gesellschaft für Pathologie, Bd. 78: S. 171-176 [PDF, 3MB]

Cook, Deborah R.; Maxwell, I. H.; Glode, L. M.; Maxwell, F.; Stevens, J. O.; Purner, M. B.; Wagner, Ernst; Curiel, David T. und Curiel, Tyler J. (1994): Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate. In: Cancer Biotherapy, Bd. 9: S. 131-141 [PDF, 1MB]

1993

Cotten, Matt; Wagner, Ernst und Birnstiel, Max L. (1993): Receptor mediated transport of DNA into eukariotic cells. In: Methods in Enzymology, Bd. 217: S. 618-644 [PDF, 3MB]

Gao, L.; Wagner, Ernst; Cotten, Matt; Agarwal, Santosh; Harris, C. E.; Romer, M.; Miller, L.; Hu, P.-C. und Curiel, David T. (1993): Direct in vivo gene transfer to the airway epithelium employing adenovirus-polylysine-DNA complexes. In: Human Gene Therapy, Bd. 4: S. 17-24 [PDF, 6MB]

Michael, S. I.; Huang, C. H.; Romer, M.; Wagner, Ernst; Hu, P.-C. und Curiel, David T. (1993): Binding-incompetent adenovirus facilitates molecular conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway. In: Journal of Biological Chemistry, Bd. 268: S. 6866-6869 [PDF, 588kB]

Cotten, Matt; Wagner, Ernst; Zatloukal, Kurt und Birnstiel, Max L. (1993): Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants. In: Journal of Virology, Bd. 67, Nr. 7: S. 3777-3785 [PDF, 3MB]

Wagner, Ernst (1993): Gentherapie. Neue Wege in der Krebsbehandlung. In: Gerbel, K. (Hrsg.): Genetische Kunst - Künstliches Leben. Wien: PVS Verleger. S. 151-154 [PDF, 880kB]

Cotten, Matt und Wagner, Ernst (1993): Non-viral approaches to gene therapy. In: Current Opinion in Biotechnology, Bd. 4, Nr. 6: S. 705-710 [PDF, 527kB]

Zatloukal, Kurt; Schmidt, Walter; Cotten, Matt; Wagner, Ernst; Stingl, Georg und Birnstiel, Max L. (1993): Somatic gene therapy for cancer. The utility of transferrinfection in generating ‘tumor vaccines’. In: Gene, Bd. 135, Nr. 1-2: S. 199-207 [PDF, 1MB]

Harris, C. E.; Agarwal, Santosh; Hu, P.-C.; Wagner, Ernst und Curiel, David T. (1993): Receptor-mediated gene transfer to airway epithelial cells in primary culture. In: American journal of respiratory cell and molecular biology, Bd. 9: S. 441-447 [PDF, 1MB]

1992

Plank, Christian; Zatloukal, Kurt; Cotten, Matt; Mechtler, Karl und Wagner, Ernst (1992): Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand. In: Bioconjugate Chemistry, Bd. 3, Nr. 6: S. 533-539 [PDF, 905kB]

Oberhauser, Berndt und Wagner, Ernst (1992): Effective incorporation of 2'-O-methyl-oligoribonucleotides into liposomes and enhanced cell association through modification with thiocholesterol. In: Nucleic Acids Resarch, Bd. 20: S. 533-538 [PDF, 696kB]

Curiel, David T.; Wagner, Ernst; Cotten, Matt; Birnstiel, Max L.; Agarwal, Santosh; Li, C.-M.; Loechel, S. und Hu, P.-C. (1992): High-efficiency gene transfer by adenovirus coupled to DNA-polylysine complexes. In: Human Gene Therapy, Bd. 3, Nr. 2: S. 147-154 [PDF, 1MB]

Wagner, Ernst; Zatloukal, Kurt; Cotten, Matt; Kirlappos, Helen; Mechtler, Karl; Curiel, David T. und Birnstiel, Max L. (1992): Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes. In: Proceedings of the National Academy of Science of the U S A, Bd. 89, Nr. 13: S. 6099-6103 [PDF, 1MB]

Curiel, David T.; Agarwal, Santosh; Romer, M.; Wagner, Ernst; Cotten, Matt; Birnstiel, Max L. und Boucher, R. C. (1992): Gene transfer to respiratory epithelial cells via the receptor-mediated endocytosis pathway. In: American Journal of Respiratory Cell and Molecular Biology, Bd. 6: S. 247-252 [PDF, 1MB]

Cotten, Matt; Wagner, Ernst; Zatloukal, Kurt; Phillips, Stephen; Curiel, David T. und Birnstiel, Max L. (1992): High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles. In: Proceedings of the National Academy of Science of the U S A, Bd. 89, Nr. 13: S. 6094-6098 [PDF, 1MB]

Wagner, Ernst; Plank, Christian; Zatloukal, Kurt; Cotten, Matt und Birnstiel, Max L. (1992): Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes. Toward a synthetic virus-like gene-transfer vehicle. In: Proceedings of the National Academy of Science of the U S A, Bd. 89, Nr. 17: S. 7934-7938 [PDF, 1MB]

Zatloukal, Kurt; Wagner, Ernst; Cotten, Matt; Phillips, Stephen; Plank, Christian; Steinlein, Peter; Curiel, David T. und Birnstiel, Max L. (1992): Transferrinfection. A Highly Efficient Way to Express Gene Constructs in Eukaryotic Cells. In: Annals of the New York Academy of Sciences, Bd. 660, Nr. 1: S. 136-153 [PDF, 2MB]

1991

Wagner, Ernst; Cotten, Matt; Foisner, Roland und Birnstiel, Max L. (1991): Transferrin-polycation-DNA complexes. The effect of polycations on the structure of the complex and DNA delivery to cells. In: Proceedings of the National Academy of Science of the U S A, Bd. 88, Nr. 10: S. 4255-4259 [PDF, 1MB]

Curiel, David T.; Agarwal, Santosh; Wagner, Ernst und Cotten, Matt (1991): Adenovirus enhancement of transferrin-polylysine-mediated gene delivery. In: Proceedings of the National Academy of Science of the U S A, Bd. 88, Nr. 19: S. 8850-8854 [PDF, 1MB]

Wagner, Ernst; Cotten, Matt; Mechtler, Karl; Kirlappos, Helen und Birnstiel, Max L. (1991): DNA-binding transferrin conjugates as functional gene-delivery agents: synthesis by linkage of polylysine or ethidium homodimer to the transferrin carbohydrate moiety. In: Bioconjugate Chemistry, Bd. 2, Nr. 4: S. 226-231 [PDF, 793kB]

Cotten, Matt; Oberhauser, Berndt; Brunar, Helmut; Holzner, Armin; Issakides, Georg; Noe, Christian R.; Schaffner, Gotthold; Wagner, Ernst und Birnstiel, Max L. (1991): 2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event. In: Nucleic Acids Research, Bd. 19: S. 2629-2635 [PDF, 6MB]

Wagner, Ernst; Oberhauser, Berndt; Holzner, Armin; Brunar, Helmut; Issakides, Georg; Schaffner, Gotthold; Cotten, Matt; Knollmüller, Max und Noe, Christian R. (1991): A simple procedure for the preparation of protected 2'-O-methyl or 2'-O-ethyl ribonucleoside-3'-O-phosphoramidites. In: Nucleic Acids Research, Bd. 19: S. 5965-5971 [PDF, 752kB]

Noe, Christian R.; Knollmüller, Max; Steinbauer, Gerhard; Wagner, Ernst; Kürner, H.; Ettmayer, Peter und Völlenkle, Horst (1991): Eine einfache Methode zur Steuerung der Reduktion von α-Alkoxy-carbonylverbindungen. In: Monatshefte für Chemie / Chemical Monthly, Bd. 122, Nr. 4: S. 299-317 [PDF, 1MB]

1990

Wagner, Ernst; Xiang, Yi-Bin; Baumann, Karl; Gück, Jürgen und Eschenmoser, Albert (1990): Chemie von alpha-Aminonitrilen. Aziridin-2-carbonitril, ein Vorläufer von rca-O3-Phosphoserinnitril und Glycolaldehyd-phosphat. In: Helvetica Chimica Acta, Bd. 73, Nr. 5: S. 1391-1409 [PDF, 1MB]

Müller, Daniel; Pitsch, Stefan; Kittaka, Atsushi; Wagner, Ernst; Wintner, Claude E. und Eschenmoser, Albert (1990): Chemie von a-Aminonitrilen. Aldomerisierung von Glycolaldehyd-phosphat zu racemischen Hexose-2,4,6-triphosphaten und (in Gegenwart von Formaldehyd) racemischen Pentose-2,4-diphosphaten: rac-Allose-2,4,6-triphosphat und rac-Ribose-2,4-diphosphat sind die Reaktionshauptprodukte. In: Helvetica Chimica Acta, Bd. 73, Nr. 5: S. 1410-1468 [PDF, 3MB]

Wagner, Ernst; Zenke, Martin; Cotten, Matt; Beug, Hartmut und Birnstiel, Max L. (1990): Transferrin-polycation conjugates as carriers for DNA uptake into cells. In: Proceedings of the National Academy of Science of the U S A, Bd. 87, Nr. 9: S. 3410-3414 [PDF, 1MB]

Zenke, Martin; Steinlein, Peter; Wagner, Ernst; Cotten, Matt; Beug, Hartmut und Birnstiel, Max L. (1990): Receptor-mediated endocytosis of transferrin-polycation conjugates. An efficient way to introduce DNA into hematopoietic cells. In: Proceedings of the National Academy of Science of the U S A, Bd. 87, Nr. 10: S. 3655-3659 [PDF, 1MB]

Cotten, Matt; Längle-Rouault, Francoise; Kirlappos, Helen; Wagner, Ernst; Mechtler, Karl; Zenke, Martin; Beug, Hartmut und Birnstiel, Max L. (1990): Transferrin-polycation-mediated introduction of DNA into human leukemic cells. Stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels. In: Proceedings of the National Academy of Science of the U S A, Bd. 87, Nr. 11: S. 4033-4037 [PDF, 1MB]

1986

Noe, Christian R.; Knollmüller, Max; Oberhauser, Berndt; Steinbauer, Gerhard und Wagner, Ernst (1986): Chirale Lactole, VI. Eine Methode zur Bestimmung der Absolutkonfiguration chiraler alpha-hydroxysubstituierter Nitrile, Alkine und Aldehyde. In: Chemische Berichte, Bd. 119, Nr. 2: S. 729-743 [PDF, 39MB]

Noe, Christian R.; Knollmüller, Max und Wagner, Ernst (1986): Ein einfaches Verfahren zur Herstellung anellierter Thiophene. In: Monatshefte für Chemie / Chemical Monthly, Bd. 117, Nr. 5: S. 621-629 [PDF, 465kB]

1985

Noe, Christian R.; Knollmüller, Max; Wagner, Ernst und Völlenkle, Horst (1985): Chirale Lactole, IV. Selektivitäten bei Acetalisierungsreaktionen enantiomerenreiner Lactole am Beispiel von Octahydro-8,9,9-trimethyl-5,8-methano-2H-1-benzopyran-2-ol. In: Chemische Berichte, Bd. 118, Nr. 5: S. 1733-1745 [PDF, 2MB]

Noe, Christian R.; Knollmüller, Max; Wagner, Ernst und Völlenkle, Horst (1985): Kohlenhydrat-Modelle, I. Kinetische und thermodynamische Effekte bei Acetalisierungsreaktionen enantiomerenreiner Thiolactole. In: Chemische Berichte, Bd. 118, Nr. 8: S. 3299-3310 [PDF, 2MB]

Diese Liste wurde am Sat Mar 23 22:55:38 2024 CET erstellt.