Anzahl der Publikationen: 107
Zeitschriftenartikel
Scotto Rosato, Anna; Krogsaeter, Einar K; Jaślan, Dawid; Abrahamian, Carla; Montefusco, Sandro; Soldati, Chiara; Spix, Barbara; Pizzo, Maria Teresa; Grieco, Giuseppina; Böck, Julia; Wyatt, Amanda; Wünkhaus, Daniela; Passon, Marcel; Stieglitz, Marc; Keller, Marco; Hermey, Guido; Markmann, Sandra; Gruber‐Schoffnegger, Doris; Cotman, Susan; Johannes, Ludger; Crusius, Dennis; Boehm, Ulrich; Wahl-Schott, Christian; Biel, Martin; Bracher, Franz; De Leonibus, Elvira; Polishchuk, Elena; Medina, Diego L; Paquet, Dominik und Grimm, Christian
(5. August 2022):
TPC2 rescues lysosomal storage in mucolipidosis type IV , Niemann–Pick type C1, and Batten disease.
In: EMBO Molecular Medicine, Bd. 14, Nr. 9
[PDF, 27MB]
Spix, Barbara; Butz, Elisabeth S.; Chen, Cheng-Chang; Rosato, Anna Scotto; Tang, Rachel; Jeridi, Aicha; Kudrina, Veronika; Plesch, Eva; Wartenberg, Philipp; Arlt, Elisabeth; Briukhovetska, Daria; Ansari, Meshal; Günsel, Gizem Günes; Conlon, Thomas M.; Wyatt, Amanda; Wetzel, Sandra; Teupser, Daniel; Holdt, Lesca M.; Ectors, Fabien; Boekhoff, Ingrid; Boehm, Ulrich; García-Añoveros, Jaime; Saftig, Paul; Giera, Martin; Kobold, Sebastian; Schiller, Herbert B.; Zierler, Susanna; Gudermann, Thomas; Wahl-Schott, Christian; Bracher, Franz; Yildirim, Ali Önder; Biel, Martin und Grimm, Christian
(2022):
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice.
In: Nature Communications, Bd. 13, 318
[PDF, 3MB]
Schanzer, Sonja; Koch, Martin; Kiefer, Andreas; Jentke, Thalia; Veith, Michael; Bracher, Franz; Bracher, Johannes und Mueller, Christoph
(2022):
Analysis of pesticide and persistent organic pollutant residues in German bats.
In: Chemosphere, Bd. 305, 135342
Fernandez, Belen; Olmedo, Pablo; Gil, Fernando; Fdez, Elena; Naaldijk, Yahaira; Rivero-Rios, Pilar; Bracher, Franz; Grimm, Christian; Churchill, Grant C. und Hilfiker, Sabine
(2022):
Iron-induced cytotoxicity mediated by endolysosomal TRPML1 channels is reverted by TFEB.
In: Cell Death & Disease, Bd. 13, Nr. 12, 1047
Jimenez, Lucia; Silva, Andreia; Calissi, Giampaolo; Grenho, Ines; Monteiro, Rita; Mayoral-Varo, Victor; Blanco-Aparicio, Carmen; Pastor, Joaquin; Bustos, Victor; Bracher, Franz; Megias, Diego; Ferreira, Bibiana I. und Link, Wolfgang
(2022):
Screening Health-Promoting Compounds for Their Capacity to Induce the Activity of FOXO3.
In: Journals of Gerontology Series A: Biological Sciences and Medical Sciences, Bd. 77, Nr. 8: S. 1485-1493
Siow, Wei Xiong; Kabiri, Yaschar; Tang, Rachel; Chao, Yu-Kai; Plesch, Eva; Eberhagen, Carola; Flenkenthaler, Florian; Froehlich, Thomas; Bracher, Franz; Grimm, Christian; Biel, Martin; Zischka, Hans; Vollmar, Angelika M. und Bartel, Karin
(2022):
Lysosomal TRPML1 regulates mitochondrial function in hepatocellular carcinoma cells.
In: Journal of Cell Science, Bd. 135, Nr. 6, jcs259455
Glas, Carina; Naydenova, Eli; Lechner, Severin; Woessner, Nathalie; Yang, Liu; Dietschreit, Johannes C. B.; Sun, Hongyan; Jung, Manfred; Kuster, Bernhard; Ochsenfeld, Christian und Bracher, Franz
(2022):
Development of hetero-triaryls as a new chemotype for subtype-selective and potent Sirt5 inhibition.
In: European Journal of Medicinal Chemistry, Bd. 240, 114594
Wang, Pengyu; Klassmueller, Thomas; Karg, Cornelia A.; Kretschmer, Maibritt; Zahler, Stefan; Braig, Simone; Bracher, Franz; Vollmar, Angelika M. und Moser, Simone
(2022):
Using the yeast three-hybrid system for the identification of small molecule-protein interactions with the example of ethinylestradiol.
In: Biological Chemistry, Bd. 403, Nr. 4: S. 421-431
Yuan, Yu; Jaslan, Dawid; Rahman, Taufiq; Bolsover, Stephen R.; Arige, Vikas; Wagner, Larry E.; Abrahamian, Carla; Tang, Rachel; Keller, Marco; Hartmann, Jonas; Rosato, Anna S.; Weiden, Eva-Maria; Bracher, Franz; Yule, David I.; Grimm, Christian und Patel, Sandip
(2022):
Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes.
In: Nature Communications, Bd. 13, Nr. 1, 4481
Rühl, Philipp; Rosato, Anna Scotto; Urban, Nicole; Gerndt, Susanne; Tang, Rachel; Abrahamian, Carla; Leser, Charlotte; Sheng, Jiansong; Jha, Archana; Vollmer, Günter; Schaefer, Michael; Bracher, Franz
ORCID: https://orcid.org/0000-0003-0009-8629 und Grimm, Christian
(2021):
Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors.
In: Scientific reports, Bd. 11, Nr. 1, 8313
[PDF, 7MB]
Krauß, Jürgen; Müller, Christoph; Klimt, Monika; Valero, Leandro Jorquera; Martinez, Jose Francisco; Müller, Martin; Bartel, Karin; Binder, Ulrike und Bracher, Franz
(2021):
Synthesis, Biological Evaluation, and Structure-Activity Relationships of 4-Aminopiperidines as Novel Antifungal Agents Targeting Ergosterol Biosynthesis.
In: Molecules, Bd. 26, Nr. 23, 7208
Krishnathas, G. Melissa; Strödke, Benjamin; Mittmann, Laura; Zech, Thomas; Berger, Lena M.; Reichel, Christoph A.; Rösser, Silvia; Schmid, Tobias; Knapp, Stefan; Müller, Susanne; Bracher, Franz; Fürst, Robert und Bischoff-Kont, Iris
(2021):
C81-evoked inhibition of the TNFR1-NF kappa B pathway during inflammatory processes for stabilization of the impaired vascular endothelial barrier for leukocytes.
In: Faseb Journal, Bd. 35, Nr. 6, e21656
Leser, Charlotte; Keller, Marco; Gerndt, Susanne; Urban, Nicole; Chen, Cheng-Chang; Schaefer, Michael; Grimm, Christian und Bracher, Franz
(2021):
Chemical and pharmacological characterization of the TRPML calcium channel blockers ML-SI1 and ML-SI3.
In: European Journal of Medicinal Chemistry, Bd. 210, 112966
Müller, Martin; Gerndt, Susanne; Chao, Yu-Kai; Zisis, Themistoklis; Ong, Nam Phuong Nguyen; Gerwien, Aaron; Urban, Nicole; Müller, Christoph; Gegenfurtner, Florian A.; Geisslinger, Franz; Ortler, Carina; Chen, Cheng-Chang; Zahler, Stefan; Biel, Martin; Schäfer, Michael; Grimm, Christian; Bracher, Franz; Vollmar, Angelika M. und Bartel, Karin
(2021):
Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth.
In: Cell Chemical Biology, Bd. 28, Nr. 8:
1119-
Ruehl, Philipp; Rosato, Anna Scotto; Urban, Nicole; Gerndt, Susanne; Tang, Rachel; Abrahamian, Carla; Leser, Charlotte; Sheng, Jiansong; Jha, Archana; Vollmer, Guenter; Schaefer, Michael; Bracher, Franz und Grimm, Christian
(2021):
Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors.
In: Scientific Reports, Bd. 11, Nr. 1, 8313
Yuan, Yu; Kilpatrick, Bethan S.; Gerndt, Susanne; Bracher, Franz; Grimm, Christian; Schapira, Anthony H. und Patel, Sandip
(2021):
The lysosomotrope GPN mobilises Ca2+ from acidic organelles.
In: Journal of Cell Science, Bd. 134, Nr. 6, jcs256578
Gerndt, Susanne; Chen, Cheng-Chang; Chao, Yu-Kai; Yuan, Yu; Burgstaller, Sandra; Rosato, Anna Scotto; Krogsaeter, Einar; Urban, Nicole; Jacob, Katharina; Ong, Nam Phuong Nguyen; Miller, Meghan T.; Keller, Marco; Vollmar, Angelika M.; Gudermann, Thomas; Zierler, Susanna; Schredelseker, Johann; Schaefer, Michael; Biel, Martin; Malli, Roland; Wahl-Schott, Christian; Bracher, Franz; Patel, Sandip und Grimm, Christian
(2020):
Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function.
In: eLife, Bd. 9, e54712
[PDF, 4MB]
Guenther, Ilka; Rimbach, Gerald; Mack, Carina; Weinert, Christoph H.; Danylec, Nicolas; Lueersen, Kai; Birringer, Marc; Bracher, Franz; Soukup, Sebastian T.; Kulling, Sabine E. und Pallauf, Kathrin
(2020):
The Putative Caloric Restriction Mimetic Resveratrol has Moderate Impact on Insulin Sensitivity, Body Composition, and the Metabolome in Mice.
In: Molecular Nutrition & Food Research, Bd. 64, Nr. 6, 1901116
Kraus, Yvonne; Glas, Carina; Melzer, Benedikt; Gao, Li; Heise, Constanze; Preusse, Monique; Ahlfeld, Julia; Bracher, Franz und Thorn-Seshold, Oliver
(2020):
Isoquinoline-based biaryls as a robust scaffold for microtubule inhibitors.
In: European Journal of Medicinal Chemistry, Bd. 186, 111865
Dekel, Noa; Eisenberg-Domovich, Yael; Karlas, Alexander; Meyer, Thomas F.; Bracher, Franz; Lebendiker, Mario; Danieli, Tsafi und Livnah, Oded
(2020):
Expression, purification and crystallization of CLK1 kinase - A potential target for antiviral therapy.
In: Protein Expression and Purification, Bd. 176, 105742
Woortman, Dirk Volker; Jürgens, Sophie; Untergehrer, Martin; Rechenberger, Julia; Fuchs, Monika; Mehlmer, Norbert; Qoura, Farah; Eckel, Georg; Stoehr, Michael; Osswald, Patrick; Le Clercq, Patrick; Hintermann, Lukas; Weuster-Botz, Dirk; Bracher, Franz und Brueck, Thomas
(2020):
Greener aromatic antioxidants for aviation and beyond.
In: Sustainable Energy & Fuels, Bd. 4, Nr. 5: S. 2153-2163
Wurzlbauer, Anne; Rueben, Katharina; Guerdal, Ece; Chaikuad, Apirat; Knapp, Stefan; Sippl, Wolfgang; Becker, Walter und Bracher, Franz
(2020):
How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine.
In: Molecules, Bd. 25, Nr. 24, 5962
Glas, Carina; Dietschreit, Johannes C. B.; Woessner, Nathalie; Urban, Lars; Ghazy, Ehab; Sippl, Wolfgang; Jung, Manfred; Ochsenfeld, Christian und Bracher, Franz
(2020):
Identification of the subtype-selective Sirt5 inhibitor balsalazide through systematic SAR analysis and rationalization via theoretical investigations.
In: European Journal of Medicinal Chemistry, Bd. 206, 112676
Schuetz, Ramona; Schmidt, Sandra und Bracher, Franz
(2020):
A versatile approach to 1-oxo-, 1-oxo-3,4-dihydro- and 1,3,4-trioxo isoquinoline alkaloids and first total synthesis of the dimeric 1-oxoisoquinoline alkaloids berbanine and berbidine.
In: Tetrahedron, Bd. 76, Nr. 19, 131150
Artarini, Anita; Meyer, Michael; Shin, Yu Jin; Huber, Kilian; Hilz, Nikolaus; Bracher, Franz; Eros, Daniel; Orfi, Laszlo; Keri, Gyorgy; Goedert, Sigrid; Neuenschwander, Martin; Kries, Jens von; Domovich-Eisenberg, Yael; Dekel, Noa; Szabadkai, Istvan; Lebendiker, Mario; Horvath, Zoltan; Danielie, Tsafi; Livnahe, Oded; Moncorge, Olivier; Frise, Rebecca; Barclay, Wendy; Meyer, Thomas F. und Karlas, Alexander
(2019):
Regulation of influenza A virus mRNA splicing by CLK1.
In: Antiviral Research, Bd. 168: S. 187-196
Schepmann, Dirk; Neue, Christina; Westphaelinger, Stefanie; Müller, Christoph; Bracher, Franz; Lange, Carsten; Bednarski, Patrick; Almansa, Carmen; Friedland, Kristina; Raebiger, Vivien; Duefer, Martina und Wuensch, Bernhard
(2019):
Pharmacological characterization of high-affinity sigma(1) receptor ligands with spirocyclic thienopyran and thienofuran scaffold.
In: Journal of Pharmacy and Pharmacology, Bd. 72, Nr. 2: S. 236-248
Koerner, Andreas; Zhou, Enchen; Muller, Christoph; Mohammed, Yassene; Herceg, Sandra; Bracher, Franz; Rensen, Patrick C. N.; Wang, Yanan; Mirakaj, Valbona und Giera, Martin
(2019):
Inhibition of Delta 24-dehydrocholesterol reductase activates pro-resolving lipid mediator biosynthesis and inflammation resolution.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 116, Nr. 41: S. 20623-20634
Junker, Julia; Chong, Isabelle; Kamp, Frits; Steiner, Harald; Giera, Martin; Müller, Christoph und Bracher, Franz
(2019):
Comparison of Strategies for the Determination of Sterol Sulfates via GC-MS Leading to a Novel Deconjugation-Derivatization Protocol.
In: Molecules, Bd. 24, Nr. 13, 2353
Gadelha, Ana Paula R.; Bravim, Barbara; Vidal, Juliana; Reignault, Lissa Catherine; Cosme, Bruno; Huber, Kilian; Bracher, Franz und de Souza, Wanderley
(2019):
Alterations on growth and cell organization of Giardia intestinalis trophozoites after treatment with KH-TFMDI, a novel class III histone deacetylase inhibitor.
In: International Journal of Medical Microbiology, Bd. 309, Nr. 2: S. 130-142
Voegerl, Katharina; Ong, Nghia; Senger, Johanna; Herp, Daniel; Schmidtkunz, Karin; Marek, Martin; Müller, Martin; Bartel, Karin; Shaik, Tajith B.; Porter, Nicholas J.; Robaa, Dina; Christianson, David W.; Romier, Christophe; Sippl, Wolfgang; Jung, Manfred und Bracher, Franz
(2019):
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors.
In: Journal of Medicinal Chemistry, Bd. 62, Nr. 3: S. 1138-1166
Pallauf, Kathrin; Chin, Dawn; Guenther, Ilka; Birringer, Marc; Lueerseni, Kai; Schultheiss, Gerald; Vieten, Sarah; Krauss, Jürgen; Bracher, Franz; Danylec, Nicolas; Soukup, Sebastian T.; Kulling, Sabine E. und Rimbach, Gerald
(2019):
Resveratrol, lunularin and dihydroresveratrol do not act as caloric restriction mimetics when administered intraperitoneally in mice.
In: Scientific Reports, Bd. 9, 4445
[PDF, 1MB]
Plesch, Eva; Chen, Cheng-Chang; Butz, Elisabeth; Rosato, Anna Scotto; Krogsaeter, Einar K.; Yinan, Hua; Bartel, Karin; Keller, Marco; Robaa, Dina; Teupser, Daniel; Holdt, Lesca M.; Vollmar, Angelika M.; Sippl, Wolfgang; Puertollano, Rosa; Medina, Diego; Biel, Martin; Wahl-Schott, Christian; Bracher, Franz und Grimm, Christian
(2018):
Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells.
In: eLife, Bd. 7, e39720
[PDF, 4MB]
Vlugt, Lucien E. P. M. van der; Eger, Katrien; Müller, Christoph; Ninaber, Dennis K.; Zarcone, Maria C.; Amatngalim, Gimano D.; Bracher, Franz; Mutius, Erika von; Smits, Hermelijn H. und Hiemstra, Pieter S.
(2018):
Farm dust reduces viral load in human bronchial epithelial cells by increasing barrier function and antiviral responses.
In: Journal of Allergy and Clinical Immunology, Bd. 141, Nr. 5: S. 1949-1952
Hubler, Zita; Allimuthu, Dharmaraja; Bederman, Ilya; Elitt, Matthew S.; Madhavan, Mayur; Allan, Kevin C.; Shick, H. Elizabeth; Garrison, Eric; Karl, Molly T.; Factor, Daniel C.; Nevin, Zachary S.; Sax, Joel L.; Thompson, Matthew A.; Fedorov, Yuriy; Jin, Jing; Wilson, William K.; Giera, Martin; Bracher, Franz; Miller, Robert H.; Tesar, Paul J. und Adams, Drew J.
(2018):
Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination.
In: Nature, Bd. 560, Nr. 7718: S. 372-376
Moustakim, Moses; Riedel, Kerstin; Schuller, Marion; Gehring, Andre P.; Monteiro, Octovia P.; Martin, Sarah P.; Fedorov, Oleg; Heer, Jag; Dixon, Darren J.; Elkins, Jonathan M.; Knapp, Stefan; Bracher, Franz und Brennan, Paul E.
(2018):
Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2.
In: Bioorganic & Medicinal Chemistry, Bd. 26, Nr. 11: S. 2965-2972
Müller, Christoph; Neugebauer, Thomas; Zill, Patrizia; Lass-Floerl, Cornelia; Bracher, Franz und Binder, Ulrike
(2018):
Sterol Composition of Clinically Relevant Mucorales and Changes Resulting from Posaconazole Treatment.
In: Molecules, Bd. 23, Nr. 5, 1218
[PDF, 1MB]
Schuller, Marion; Riede, Kerstin; Gibbs-Seymour, Ian; Uth, Kristin; Sieg, Christian; Gehring, Andre P.; Ahel, Ivan; Bracher, Franz; Kessler, Benedikt M.; Elkins, Jonathan M. und Knapp, Stefan
(2017):
Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of Polyadenosine-Diphosphate-Ribose Polymerase 14.
In: ACS Chemical Biology, Bd. 12, Nr. 11: S. 2866-2874
Mailaender-Sanchez, Daniela; Braunsdorf, Christina; Grumaz, Christian; Müller, Christoph; Lorenz, Stefan; Stevens, Philip; Wagener, Jeanette; Hebecker, Betty; Hube, Bernhard; Bracher, Franz; Sohn, Kai und Schaller, Martin
(2017):
Antifungal defense of probiotic Lactobacillus rhamnosus GG is mediated by blocking adhesion and nutrient depletion.
In: PLOS One
12(10), e0184438
[PDF, 5MB]
Farias Vercoza, Brunno Renato; Prado Godinho, Joseane Lima; Teixeira de Macedo-Silva, Sara; Huber, Kilian; Bracher, Franz; Souza, Wanderley de und Fernandes Rodrigues, Juliany Cola
(2017):
KH-TFMDI, a novel sirtuin inhibitor, alters the cytoskeleton and mitochondrial metabolism promoting cell death in Leishmania amazonensis.
In: Apoptosis, Bd. 22, Nr. 9: S. 1169-1188
Fanter, Lena; Müller, Christoph; Schepmann, Dirk; Bracher, Franz und Wünsch, Bernhard
(2017):
Chiral-pool synthesis of 1,2,4-trisubstituted 1,4-diazepanes as novel sigma(1) receptor ligands.
In: Bioorganic & Medicinal Chemistry, Bd. 25, Nr. 17: S. 4778-4799
Gsaller, Fabio; Hortschansky, Peter; Furukawa, Takanori; Carr, Paul D.; Rash, Bharat; Capilla, Javier; Müller, Christoph; Bracher, Franz; Bowyer, Paul; Haas, Hubertus; Brakhage, Axel A. und Bromley, Michael J.
(2016):
Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex.
In: PLOS Pathogens
12(7), e1005775
[PDF, 4MB]
Karlas, Alexander; Berre, Stefano; Couderc, Therese; Varjak, Margus; Braun, Peter; Meyer, Michael; Gangneux, Nicolas; Karo-Astover, Liis; Weege, Friderike; Raftery, Martin; Schönrich, Günther; Klemm, Uwe; Wurzlbauer, Anne; Bracher, Franz; Merits, Andres; Meyer, Thomas F. und Lecuit, Marc
(2016):
A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs.
In: Nature Communications, Bd. 7, 11320
[PDF, 2MB]
Popp, Tobias A.; Tallant, Cynthia; Rogers, Catherine; Fedorov, Oleg; Brennan, Paul E.; Müller, Susanne; Knapp, Stefan und Bracher, Franz
(2016):
Development of Selective CBP/P300 Benzoxazepine Bromodomain Inhibitors.
In: Journal of Medicinal Chemistry, Bd. 59, Nr. 19: S. 8889-8912
Keller, Marco; Wolfgardt, Annette; Müller, Christoph; Wilcken, Rainer; Böckler, Frank M.; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Balliano, Gianni und Bracher, Franz
(2016):
Arylpiperidines as a new class of oxidosqualene cyclase inhibitors.
In: European Journal of Medicinal Chemistry, Bd. 109: S. 13-22
Funke, Stefanie; Matilainen, Julia; Nalenz, Heiko; Bechtold-Peters, Karoline; Mahler, Hanns-Christian; Vetter, Florian; Müller, Christoph; Bracher, Franz und Friess, Wolfgang
(2016):
Optimization of the bake-on siliconization of cartridges. Part II: Investigations into burn-in time and temperature.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 105: S. 209-222
Merk, Henriette; Zhang, Siwei; Lehr, Thorsten; Müller, Christoph; Ulrich, Melanie; Bibb, James A.; Adams, Ralf H.; Bracher, Franz; Zahler, Stefan; Vollmar, Angelika M. und Liebl, Johanna
(2016):
Inhibition of endothelial Cdk5 reduces tumor growth by promoting non-productive angiogenesis.
In: Oncotarget, Bd. 7, Nr. 5: S. 6088-6104
Kern, Selina; Agarwal, Shruti; Huber, Kilian; Gehring, André P.; Strödke, Benjamin; Wirth, Christine C.; Brügl, Thomas; Abodo, Liliane Onambele; Dandekar, Thomas; Doerig, Christian; Fischer, Rainer; Tobin, Andrew B.; Alam, Mahmood M.; Bracher, Franz und Pradel, Gabriele
(2014):
Inhibition of the SR Protein-Phosphorylating CLK Kinases of Plasmodium falciparum Impairs Blood Stage Replication and Malaria Transmission.
In: PLOS ONE
9(9), e105732
[PDF, 3MB]
Chen, Cheng-Chang; Keller, Marco; Hess, Martin; Schiffmann, Raphael; Urban, Nicole; Wolfgardt, Annette; Schaefer, Michael; Bracher, Franz; Biel, Martin; Wahl-Schott, Christian und Grimm, Christian
(2014):
A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV.
In: Nature Communications, Bd. 5, 4681
[PDF, 1MB]
Grimm, Christian; Holdt, Lesca M.; Chen, Cheng-Chang; Hassan, Sami; Müller, Christoph; Jörs, Simone; Cuny, Hartmut; Kissing, Sandra; Schröder, Bernd; Butz, Elisabeth; Northoff, Bernd; Castonguay, Jan; Luber, Christian A.; Moser, Markus; Spahn, Saskia; Luellmann-Rauch, Renate; Fendel, Christina; Klugbauer, Norbert; Griesbeck, Oliver; Haas, Albert; Mann, Matthias; Bracher, Franz; Teupser, Daniel; Saftig, Paul; Biel, Martin und Wahl-Schott, Christian
(2014):
High susceptibility to fatty liver disease in two-pore channel 2-deficient mice.
In: Nature Communications, Bd. 5, 4699
[PDF, 3MB]
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